|
Name |
Accession |
Description |
Interval |
E-value |
| COG4646 |
COG4646 |
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair]; |
158-1893 |
0e+00 |
|
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair];
Pssm-ID: 443684 [Multi-domain] Cd Length: 1711 Bit Score: 913.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 158 TGEYRPEASEQILDDFAIPDEPESYDSVRRNELEQYDALENEDILENEITDEELAIEDQMVTMAEYSEELENEKQKDEMD 237
Cdd:COG4646 102 EGEEVEGLSEGLKIAIELSRLGSELEAVLGAEAGDGLAAAIEAPIEIENSEKLKAASTLLETVTEPEVEAELAEVELLSA 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 238 VSyvvPADKSGGPVPEKRNYHYNLWdlpIGGAKTRYKWNIEAIKLLKTLETEGRLAGYEEQKVLSKYAGWGGIPQAFDDK 317
Cdd:COG4646 182 EA---AAADEEVSSESLASTPAAAR---AGAAKILAVLLAEGALALKLARAAERLALAESGGERRNNAKIEELALELDEE 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 318 NSEWEKEYAELHALLNDEEYAAARATVNNAFYTSPVICTCINRALVSFGFHGGNLLEPSMGTGNFFGSLPASMRSANLYG 397
Cdd:COG4646 256 LEADELANAAADAELRDATKAAELATELDARARESDARAAGFRGGEGAILLEGGGLEGLAGGLIGEGGLGIGAEGAGSAG 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 398 VELDSISGRIAKQLYQTANITIGGFEHTEYPDNFFDVAVGNVPFGDYKVFDKKYNKYNFRIHDYFLAKALDQVRPGGIVA 477
Cdd:COG4646 336 ALTAALLNEQLAGAGGAIALLADPLAADLAFGLFPFLFVAANVFGGLKKLFLADLHILFLSAAARLVRGRDALATLGSLK 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 478 FVTTKGTLDKSNPAIRQYLAQRAELIGAVRLPNTAFKDNAGTEVTCDILFLQKRERKMDVEPDWVH-LGYTDDGIPINSY 556
Cdd:COG4646 416 DAFPKARARRAARIAADLAASVAASLAAAARALATAEILEITEIREADRLEAEADEDLKDLEVVFAeLEGEGAIIDVNRY 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 557 YVEHPEMVLghmeydnriygkdsryttcvnldpefnlyealneavqnmhaeliefqrleeaeekgediiPADPDVRNFSF 636
Cdd:COG4646 496 FADHPEVTP------------------------------------------------------------PADPSVKDGSY 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 637 CFVDGKLYYRENSQMYRREVSNTVEERIRAMDEIRAATRHLIDIQTEGcsDKQLEKKQGKLNEKYDRFVEKYGPITSQPN 716
Cdd:COG4646 516 TFEDGVLYVDEAHNFKNLEVPATKMRRVAGLIPLRDAVRELIEAQAED--DGSQKALRMRLNCRYDAFVAKYGPINSRPN 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 717 SRAFRDDSDYPLLCSLEEVDEDGHVK-KADMFYKQTIKAKmVIDHVATAVEALNVSINEFGTVNIPYMlsiyepdltkAK 795
Cdd:COG4646 594 LRAFRDDPDYPLLLSLEEYDEETGTArKADIFTKRVIRPP-TETSVDTAAEALAVSLNERGRVDLDYM----------AE 662
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 796 ASfvkkaGQDIDEItfseeaekelkravmIDELSGLIFLNPSAYNPnnpnsGWETADEYLSGNVRDKLRIARAAVDapdi 875
Cdd:COG4646 663 LT-----GTPISNS---------------LAELYGMIYLDPDTLED-----GWVTFDEYLSGNVREKLAAARAAAE---- 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 876 lpEERELFQKNVSALMQVQPKDLDASEIDVKIGTTWIEPEDYEQFIYELLNTPkraraarsqwyssgIQIHLNKLNMEWF 955
Cdd:COG4646 714 --LDPRTFGENVTALELVQPEDLEPSEIDVRLGATWIPKTRFEAFIRELLGTP--------------ITVSYSPETGEWS 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 956 IENKSMdkrSVAATRTYGTSRMDAYSIFENTLNLRTVTVKDRIDDGdgkyHYEVNKNETMLAREKQNLMKDAFKEWLFSD 1035
Cdd:COG4646 778 VKGKNG---NAAATSTYGTERANAPELLEDALNVADIRIADPVPDE----RRVLNTEETEAAKEKQEAIKEAFAEWVWED 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1036 PDRRAKYVSYYNETFNNVRLREYDGSYLQFPGMNPKIELKPHQKNAVARILMGGNTLLAHCVGAGKSFEMMSACMEQKRL 1115
Cdd:COG4646 851 PERAERLVRLYNDKFNSIVPREYDGSHLKFPGDSRKISLRPHQKNAVARILYGGNTLLAHEVGAGKTFTMVAAAMELRRL 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1116 GLANKTVMVVPKSLIGQTASEFLRLYPSANILVATERDFEKSRRKQFISRIATGDYDCIIMSHSQFEKIPISAERKKAMI 1195
Cdd:COG4646 931 GLANKPMIVVPNHLLEQDAPSKLNLYAAANILIATKTDFEKGTRLVFCADIATGDYDAVIIGHIQFEKIPASGERQEEIL 1010
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1196 DRQIEEISYSITEMKARNGERWTIKQMEAQKKKLEEQIRELTDESRKDDLITFEELGIDSIMVDEAHGFKNLAIFSKMNN 1275
Cdd:COG4646 1011 EEQIAEILKAIKELKAVVRKRFTVKQLESTKKLGAGKLKQLDLLALKDLDVPWEPLDVDQLFGRGSRQGNNNFLVTKMRN 1090
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1276 VAGISSTGSKKATDMQMKCQYISELNGGRGIVFATGTPISNTMCELYVMQLYLQREKLEQMGIYHFDAWAANFGEVTTAL 1355
Cdd:COG4646 1091 VAGLAFSDAAKLSDYFGKQRYRDELTAGKGVVVATGTDESNLMYELYTAQAYLQLLLLGKQGLTNFDTWASTLEELVTAA 1170
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1356 ELTVEGSGFRFKSRFNKFTNLPELMNVFREVADVQTKDMLDLPVPElrdGKYVIVESEPDWYVKQVMEEFVARAERIRGG 1435
Cdd:COG4646 1171 ELAPERTAYRANTREAKAVNLPEEDVMIKEAEDAKTADELLLPTPE---KISGGVATKPSEVQKELLEELEERAAIVRKN 1247
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1436 GVDPSVDNFLKITHEARLLGTDARLleaAAPNNPGGKLNKVADNVFMEYEKAENEGKIGC-QLIFSDIGTPKENwnesml 1514
Cdd:COG4646 1248 DGEPDRDNMLVITDDGRKAALDQRL---DIKTLPDDEGSLVALCVTNIDRIWEDNPESKLtQLVFCDLSTPKGD------ 1318
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1515 tegywkhsgnevrasGEFDVYNYLKTELVRKGIPADEIAFIHDAKSDAQRETLFKDMRTGKKKVLIGSTDKCGTGVNVQT 1594
Cdd:COG4646 1319 ---------------GTFNDLEDIREKLIEEEIAELEIAFIHLALDDQEKAELFARDRLGAVEKLRISTAKMGAGTNVRL 1383
|
1450 1460 1470 1480 1490 1500 1510 1520
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1595 HLVAMHHVDCPWKPSCIEQREGRGLRQGNENESVAVYRYVTKGTFDAYSWSLVENKQRFISQVMTSRAVSRTCEDIDEAT 1674
Cdd:COG4646 1384 LLEATHDLDVPWRPRDAEQRAGRGRRQGNENEEVEEIRYVTENTFDAYLWQAAETKQKFIAQIMTSKSPVRSLEDVDEAA 1463
|
1530 1540 1550 1560 1570 1580 1590 1600
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1675 LSYAEIKAVATGNTMIKEKMEIDNDVQRLKLLKAAYDSQKYGLQDNFIIRFPKLIKAAEEKLACVKQDV--EMRDQAVLA 1752
Cdd:COG4646 1464 LSYAERKALAAGRPKEKEKMDLDIEVLKLKLLDAAALEQLYAEEDKLRKSYLDEEEALEERIEAATKDLrlARAASQEEA 1543
|
1610 1620 1630 1640 1650 1660 1670 1680
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1753 SVDFAIKIGNITFTERADGG--TGMLEAISRCKTGETSSIGTFKGFELLVE-KNFLDINYLVLRGKTDYKTELSTSPVGN 1829
Cdd:COG4646 1544 DEQESASKEAAAGEKKAAAAelLAALQAAGLIVLDGGRTPRGEKGGGLLARaLLEAATLLLPIEEAEGSEGADATGDRRT 1623
|
1690 1700 1710 1720 1730 1740
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2744976818 1830 --MVKLENLFNGIQDNIEflEKKIEQYKGDLEASKTEYEKPFAYEEELRTKLARQEELNAMLDLEN 1893
Cdd:COG4646 1624 gaAAEIELAAEALILNLA--ERLERALRDGAEEEEIAPRELEAALKEEAALLARAGELAELELDKA 1687
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
1072-1177 |
1.19e-10 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 62.89 E-value: 1.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1072 IELKPHQKNAVARILMG-GNTLLAHCVGAGKSFEMMSACMEQKRLGLANKTVMVVP-KSLIGQTASEFLRLYPSANILVA 1149
Cdd:smart00487 7 EPLRPYQKEAIEALLSGlRDVILAAPTGSGKTLAALLPALEALKRGKGGRVLVLVPtRELAEQWAEELKKLGPSLGLKVV 86
|
90 100
....*....|....*....|....*...
gi 2744976818 1150 TErdFEKSRRKQFISRIATGDYDCIIMS 1177
Cdd:smart00487 87 GL--YGGDSKREQLRKLESGKTDILVTT 112
|
|
| SF2_C_SNF |
cd18793 |
C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) ... |
1533-1634 |
1.48e-07 |
|
C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) family includes chromatin-remodeling factors, such as CHD proteins and SMARCA proteins, recombination proteins Rad54, and many others. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350180 [Multi-domain] Cd Length: 135 Bit Score: 52.09 E-value: 1.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1533 DVYNYLKTELVRKGIpadEIAFIHDAKSDAQRETLFKDMRTGKK-KVLIGSTDKCGTGVNVQ--THLVamhHVDCPWKPS 1609
Cdd:cd18793 38 DTLDILEEALRERGI---KYLRLDGSTSSKERQKLVDRFNEDPDiRVFLLSTKAGGVGLNLTaaNRVI---LYDPWWNPA 111
|
90 100
....*....|....*....|....*
gi 2744976818 1610 CIEQREGRGLRQGNENEsVAVYRYV 1634
Cdd:cd18793 112 VEEQAIDRAHRIGQKKP-VVVYRLI 135
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
1542-1622 |
1.24e-06 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 48.75 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1542 LVRKGIPadeIAFIHDAKSDAQRETLFKDMRTGKKKVLIgSTDKCGTGVNVqTHLVAMHHVDCPWKPSCIEQREGRGLRQ 1621
Cdd:pfam00271 34 LEKEGIK---VARLHGDLSQEEREEILEDFRKGKIDVLV-ATDVAERGLDL-PDVDLVINYDLPWNPASYIQRIGRAGRA 108
|
.
gi 2744976818 1622 G 1622
Cdd:pfam00271 109 G 109
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG4646 |
COG4646 |
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair]; |
158-1893 |
0e+00 |
|
Adenine-specific DNA methylase, N12 class [Replication, recombination and repair];
Pssm-ID: 443684 [Multi-domain] Cd Length: 1711 Bit Score: 913.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 158 TGEYRPEASEQILDDFAIPDEPESYDSVRRNELEQYDALENEDILENEITDEELAIEDQMVTMAEYSEELENEKQKDEMD 237
Cdd:COG4646 102 EGEEVEGLSEGLKIAIELSRLGSELEAVLGAEAGDGLAAAIEAPIEIENSEKLKAASTLLETVTEPEVEAELAEVELLSA 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 238 VSyvvPADKSGGPVPEKRNYHYNLWdlpIGGAKTRYKWNIEAIKLLKTLETEGRLAGYEEQKVLSKYAGWGGIPQAFDDK 317
Cdd:COG4646 182 EA---AAADEEVSSESLASTPAAAR---AGAAKILAVLLAEGALALKLARAAERLALAESGGERRNNAKIEELALELDEE 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 318 NSEWEKEYAELHALLNDEEYAAARATVNNAFYTSPVICTCINRALVSFGFHGGNLLEPSMGTGNFFGSLPASMRSANLYG 397
Cdd:COG4646 256 LEADELANAAADAELRDATKAAELATELDARARESDARAAGFRGGEGAILLEGGGLEGLAGGLIGEGGLGIGAEGAGSAG 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 398 VELDSISGRIAKQLYQTANITIGGFEHTEYPDNFFDVAVGNVPFGDYKVFDKKYNKYNFRIHDYFLAKALDQVRPGGIVA 477
Cdd:COG4646 336 ALTAALLNEQLAGAGGAIALLADPLAADLAFGLFPFLFVAANVFGGLKKLFLADLHILFLSAAARLVRGRDALATLGSLK 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 478 FVTTKGTLDKSNPAIRQYLAQRAELIGAVRLPNTAFKDNAGTEVTCDILFLQKRERKMDVEPDWVH-LGYTDDGIPINSY 556
Cdd:COG4646 416 DAFPKARARRAARIAADLAASVAASLAAAARALATAEILEITEIREADRLEAEADEDLKDLEVVFAeLEGEGAIIDVNRY 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 557 YVEHPEMVLghmeydnriygkdsryttcvnldpefnlyealneavqnmhaeliefqrleeaeekgediiPADPDVRNFSF 636
Cdd:COG4646 496 FADHPEVTP------------------------------------------------------------PADPSVKDGSY 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 637 CFVDGKLYYRENSQMYRREVSNTVEERIRAMDEIRAATRHLIDIQTEGcsDKQLEKKQGKLNEKYDRFVEKYGPITSQPN 716
Cdd:COG4646 516 TFEDGVLYVDEAHNFKNLEVPATKMRRVAGLIPLRDAVRELIEAQAED--DGSQKALRMRLNCRYDAFVAKYGPINSRPN 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 717 SRAFRDDSDYPLLCSLEEVDEDGHVK-KADMFYKQTIKAKmVIDHVATAVEALNVSINEFGTVNIPYMlsiyepdltkAK 795
Cdd:COG4646 594 LRAFRDDPDYPLLLSLEEYDEETGTArKADIFTKRVIRPP-TETSVDTAAEALAVSLNERGRVDLDYM----------AE 662
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 796 ASfvkkaGQDIDEItfseeaekelkravmIDELSGLIFLNPSAYNPnnpnsGWETADEYLSGNVRDKLRIARAAVDapdi 875
Cdd:COG4646 663 LT-----GTPISNS---------------LAELYGMIYLDPDTLED-----GWVTFDEYLSGNVREKLAAARAAAE---- 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 876 lpEERELFQKNVSALMQVQPKDLDASEIDVKIGTTWIEPEDYEQFIYELLNTPkraraarsqwyssgIQIHLNKLNMEWF 955
Cdd:COG4646 714 --LDPRTFGENVTALELVQPEDLEPSEIDVRLGATWIPKTRFEAFIRELLGTP--------------ITVSYSPETGEWS 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 956 IENKSMdkrSVAATRTYGTSRMDAYSIFENTLNLRTVTVKDRIDDGdgkyHYEVNKNETMLAREKQNLMKDAFKEWLFSD 1035
Cdd:COG4646 778 VKGKNG---NAAATSTYGTERANAPELLEDALNVADIRIADPVPDE----RRVLNTEETEAAKEKQEAIKEAFAEWVWED 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1036 PDRRAKYVSYYNETFNNVRLREYDGSYLQFPGMNPKIELKPHQKNAVARILMGGNTLLAHCVGAGKSFEMMSACMEQKRL 1115
Cdd:COG4646 851 PERAERLVRLYNDKFNSIVPREYDGSHLKFPGDSRKISLRPHQKNAVARILYGGNTLLAHEVGAGKTFTMVAAAMELRRL 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1116 GLANKTVMVVPKSLIGQTASEFLRLYPSANILVATERDFEKSRRKQFISRIATGDYDCIIMSHSQFEKIPISAERKKAMI 1195
Cdd:COG4646 931 GLANKPMIVVPNHLLEQDAPSKLNLYAAANILIATKTDFEKGTRLVFCADIATGDYDAVIIGHIQFEKIPASGERQEEIL 1010
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1196 DRQIEEISYSITEMKARNGERWTIKQMEAQKKKLEEQIRELTDESRKDDLITFEELGIDSIMVDEAHGFKNLAIFSKMNN 1275
Cdd:COG4646 1011 EEQIAEILKAIKELKAVVRKRFTVKQLESTKKLGAGKLKQLDLLALKDLDVPWEPLDVDQLFGRGSRQGNNNFLVTKMRN 1090
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1276 VAGISSTGSKKATDMQMKCQYISELNGGRGIVFATGTPISNTMCELYVMQLYLQREKLEQMGIYHFDAWAANFGEVTTAL 1355
Cdd:COG4646 1091 VAGLAFSDAAKLSDYFGKQRYRDELTAGKGVVVATGTDESNLMYELYTAQAYLQLLLLGKQGLTNFDTWASTLEELVTAA 1170
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1356 ELTVEGSGFRFKSRFNKFTNLPELMNVFREVADVQTKDMLDLPVPElrdGKYVIVESEPDWYVKQVMEEFVARAERIRGG 1435
Cdd:COG4646 1171 ELAPERTAYRANTREAKAVNLPEEDVMIKEAEDAKTADELLLPTPE---KISGGVATKPSEVQKELLEELEERAAIVRKN 1247
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1436 GVDPSVDNFLKITHEARLLGTDARLleaAAPNNPGGKLNKVADNVFMEYEKAENEGKIGC-QLIFSDIGTPKENwnesml 1514
Cdd:COG4646 1248 DGEPDRDNMLVITDDGRKAALDQRL---DIKTLPDDEGSLVALCVTNIDRIWEDNPESKLtQLVFCDLSTPKGD------ 1318
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1515 tegywkhsgnevrasGEFDVYNYLKTELVRKGIPADEIAFIHDAKSDAQRETLFKDMRTGKKKVLIGSTDKCGTGVNVQT 1594
Cdd:COG4646 1319 ---------------GTFNDLEDIREKLIEEEIAELEIAFIHLALDDQEKAELFARDRLGAVEKLRISTAKMGAGTNVRL 1383
|
1450 1460 1470 1480 1490 1500 1510 1520
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1595 HLVAMHHVDCPWKPSCIEQREGRGLRQGNENESVAVYRYVTKGTFDAYSWSLVENKQRFISQVMTSRAVSRTCEDIDEAT 1674
Cdd:COG4646 1384 LLEATHDLDVPWRPRDAEQRAGRGRRQGNENEEVEEIRYVTENTFDAYLWQAAETKQKFIAQIMTSKSPVRSLEDVDEAA 1463
|
1530 1540 1550 1560 1570 1580 1590 1600
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1675 LSYAEIKAVATGNTMIKEKMEIDNDVQRLKLLKAAYDSQKYGLQDNFIIRFPKLIKAAEEKLACVKQDV--EMRDQAVLA 1752
Cdd:COG4646 1464 LSYAERKALAAGRPKEKEKMDLDIEVLKLKLLDAAALEQLYAEEDKLRKSYLDEEEALEERIEAATKDLrlARAASQEEA 1543
|
1610 1620 1630 1640 1650 1660 1670 1680
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1753 SVDFAIKIGNITFTERADGG--TGMLEAISRCKTGETSSIGTFKGFELLVE-KNFLDINYLVLRGKTDYKTELSTSPVGN 1829
Cdd:COG4646 1544 DEQESASKEAAAGEKKAAAAelLAALQAAGLIVLDGGRTPRGEKGGGLLARaLLEAATLLLPIEEAEGSEGADATGDRRT 1623
|
1690 1700 1710 1720 1730 1740
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2744976818 1830 --MVKLENLFNGIQDNIEflEKKIEQYKGDLEASKTEYEKPFAYEEELRTKLARQEELNAMLDLEN 1893
Cdd:COG4646 1624 gaAAEIELAAEALILNLA--ERLERALRDGAEEEEIAPRELEAALKEEAALLARAGELAELELDKA 1687
|
|
| YtxK |
COG0827 |
Adenine-specific DNA N6-methylase [Replication, recombination and repair]; |
277-545 |
6.49e-35 |
|
Adenine-specific DNA N6-methylase [Replication, recombination and repair];
Pssm-ID: 440589 [Multi-domain] Cd Length: 327 Bit Score: 137.39 E-value: 6.49e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 277 IEAIKLLKTLETEGRLAGYEEQKVLSKYAGWGGipqafddknseWEKEYAELHALLNDEEYAAARATV-NNAFYTSPVIC 355
Cdd:COG0827 33 IETLENLLDGEVEGKPTEEAKKKLKKNYQKLQL-----------ESLSKEEIRKALQLALLKGMKESVqPNHQMTPDAIG 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 356 TCINRALVSFG-FHGGNLLEPSMGTGNFFGSLPASMR-SANLYGVELDSISGRIAKQLY----QTANITIGGFEHTEYPD 429
Cdd:COG0827 102 LLIGYLVEKFTkKEGLRILDPAVGTGNLLTTVLNQLKkKVNAYGVEVDDLLIRLAAVLAnlqgHPVELFHQDALQPLLID 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 430 nFFDVAVGNVPFGDYKVFDKKYN------KYNFRIHDYFLAKALDQVRPGGIVAFVTTKGTLD-KSNPAIRQYLAQRAEL 502
Cdd:COG0827 182 -PVDVVISDLPVGYYPNDERAKRfklkadEGHSYAHHLFIEQSLNYLKPGGYLFFLVPSNLFEsDQAAQLREFLKEKAHI 260
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 2744976818 503 IGAVRLPNTAFKDNAGTEvtcDILFLQKRERKmDVEPDWVHLG 545
Cdd:COG0827 261 QGLIQLPESLFKNEAAAK---SILILQKKGEG-TKQPKEVLLA 299
|
|
| HepA |
COG0553 |
Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination, ... |
1030-1658 |
1.03e-22 |
|
Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination, and repair];
Pssm-ID: 440319 [Multi-domain] Cd Length: 682 Bit Score: 105.69 E-value: 1.03e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1030 EWLFSDPDRRAKYVSYYNETFNNVRLREYDGSYLQFPgMNPKIELKPHQKNAVARIL----MGGNTLLAHCVGAGKSFEM 1105
Cdd:COG0553 199 AELLLLLELLLELELLAEAAVDAFRLRRLREALESLP-AGLKATLRPYQLEGAAWLLflrrLGLGGLLADDMGLGKTIQA 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1106 MSACMEQKRLGLANKTVMVVPKSLIGQTASEFLRLYPSANILVATERDFEKSRRKQFisriatGDYDCIIMSHSQFekip 1185
Cdd:COG0553 278 LALLLELKERGLARPVLIVAPTSLVGNWQRELAKFAPGLRVLVLDGTRERAKGANPF------EDADLVITSYGLL---- 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1186 isaerkkamidrqieeisysitemkarngerwtikqmeaqkkkleeqireltdesrKDDLITFEELGIDSIMVDEAHGFK 1265
Cdd:COG0553 348 --------------------------------------------------------RRDIELLAAVDWDLVILDEAQHIK 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1266 NlaifskmnnvagiSSTGSKKAtdmqmkcqyISELNGgRGIVFATGTPISNTMCELY-VMQLyLQREKLeqmgiyhfdaw 1344
Cdd:COG0553 372 N-------------PATKRAKA---------VRALKA-RHRLALTGTPVENRLEELWsLLDF-LNPGLL----------- 416
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1345 aanfgevttaleltveGSGFRFKSRFNKF------TNLPELMNVFREV------ADVQTkdmlDLPVpelRDGKYVIVES 1412
Cdd:COG0553 417 ----------------GSLKAFRERFARPiekgdeEALERLRRLLRPFllrrtkEDVLK----DLPE---KTEETLYVEL 473
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1413 EPDW------YVKQVMEEFVARAERIRGGGVdpsvdnfLKITHEARLLGTDARLL--EAAAPNNPGGKLNKVA---DNVF 1481
Cdd:COG0553 474 TPEQralyeaVLEYLRRELEGAEGIRRRGLI-------LAALTRLRQICSHPALLleEGAELSGRSAKLEALLellEELL 546
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1482 MEYEKAenegkigcqLIFSdigtpkenWNESMLtegywkhsgnevrasgefdvyNYLKTELVRKGIPAdeiAFIHDAKSD 1561
Cdd:COG0553 547 AEGEKV---------LVFS--------QFTDTL---------------------DLLEERLEERGIEY---AYLHGGTSA 585
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1562 AQRETLFKDMRTGKK-KVLIGSTDKCGTGVNVQ--THLVamhHVDCPWKPSCIEQREGRGLRQGNENeSVAVYRYVTKGT 1638
Cdd:COG0553 586 EERDELVDRFQEGPEaPVFLISLKAGGEGLNLTaaDHVI---HYDLWWNPAVEEQAIDRAHRIGQTR-DVQVYKLVAEGT 661
|
650 660
....*....|....*....|
gi 2744976818 1639 FDAYSWSLVENKQRFISQVM 1658
Cdd:COG0553 662 IEEKILELLEEKRALAESVL 681
|
|
| HsdM |
COG0286 |
Type I restriction-modification system, DNA methylase subunit [Defense mechanisms]; |
348-534 |
2.14e-13 |
|
Type I restriction-modification system, DNA methylase subunit [Defense mechanisms];
Pssm-ID: 440055 [Multi-domain] Cd Length: 243 Bit Score: 71.76 E-value: 2.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 348 FYTSPVICtcinRALVS--FGFHGGNLLEPSMGTGNFF--------GSLPASMRSANLYGVELDSISGRIAK-----QLY 412
Cdd:COG0286 25 FYTPREVV----RLMVEllDPKPGETVYDPACGSGGFLveaaeylkEHGGDERKKLSLYGQEINPTTYRLAKmnlllHGI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 413 QTANITIGG-FEHTEYPDNFFDVAVGNVPFGDYKVFDKKYNKYNFRIH---------DY-FLAKALDQVRPGGIVAFVTT 481
Cdd:COG0286 101 GDPNIELGDtLSNDGDELEKFDVVLANPPFGGKWKKEELKDDLLGRFGyglppksnaDLlFLQHILSLLKPGGRAAVVLP 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2744976818 482 KGTL-DKSNPAIRQYLAQRAELIGAVRLPNTAFKdNAGTEvTCdILFLQKRERK 534
Cdd:COG0286 181 DGVLfRGAEKEIRKKLLENDLLEAIIGLPSNLFY-NTGIP-TC-ILFLTKGKPE 231
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
1072-1177 |
1.19e-10 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 62.89 E-value: 1.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1072 IELKPHQKNAVARILMG-GNTLLAHCVGAGKSFEMMSACMEQKRLGLANKTVMVVP-KSLIGQTASEFLRLYPSANILVA 1149
Cdd:smart00487 7 EPLRPYQKEAIEALLSGlRDVILAAPTGSGKTLAALLPALEALKRGKGGRVLVLVPtRELAEQWAEELKKLGPSLGLKVV 86
|
90 100
....*....|....*....|....*...
gi 2744976818 1150 TErdFEKSRRKQFISRIATGDYDCIIMS 1177
Cdd:smart00487 87 GL--YGGDSKREQLRKLESGKTDILVTT 112
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
1537-1622 |
2.21e-08 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 52.98 E-value: 2.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1537 YLKTELVRKGIPadeIAFIHDAKSDAQRETLFKDMRTGKKKVLIgSTDKCGTGVNVQT-HLVAmhHVDCPWKPSCIEQRE 1615
Cdd:smart00490 2 ELAELLKELGIK---VARLHGGLSQEEREEILDKFNNGKIKVLV-ATDVAERGLDLPGvDLVI--IYDLPWSPASYIQRI 75
|
....*..
gi 2744976818 1616 GRGLRQG 1622
Cdd:smart00490 76 GRAGRAG 82
|
|
| SF2_C_SNF |
cd18793 |
C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) ... |
1533-1634 |
1.48e-07 |
|
C-terminal helicase domain of the SNF family helicases; The Sucrose Non-Fermenting (SNF) family includes chromatin-remodeling factors, such as CHD proteins and SMARCA proteins, recombination proteins Rad54, and many others. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350180 [Multi-domain] Cd Length: 135 Bit Score: 52.09 E-value: 1.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1533 DVYNYLKTELVRKGIpadEIAFIHDAKSDAQRETLFKDMRTGKK-KVLIGSTDKCGTGVNVQ--THLVamhHVDCPWKPS 1609
Cdd:cd18793 38 DTLDILEEALRERGI---KYLRLDGSTSSKERQKLVDRFNEDPDiRVFLLSTKAGGVGLNLTaaNRVI---LYDPWWNPA 111
|
90 100
....*....|....*....|....*
gi 2744976818 1610 CIEQREGRGLRQGNENEsVAVYRYV 1634
Cdd:cd18793 112 VEEQAIDRAHRIGQKKP-VVVYRLI 135
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
1542-1622 |
1.24e-06 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 48.75 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1542 LVRKGIPadeIAFIHDAKSDAQRETLFKDMRTGKKKVLIgSTDKCGTGVNVqTHLVAMHHVDCPWKPSCIEQREGRGLRQ 1621
Cdd:pfam00271 34 LEKEGIK---VARLHGDLSQEEREEILEDFRKGKIDVLV-ATDVAERGLDL-PDVDLVINYDLPWNPASYIQRIGRAGRA 108
|
.
gi 2744976818 1622 G 1622
Cdd:pfam00271 109 G 109
|
|
| DEXHc_Snf |
cd17919 |
DEXH/Q-box helicase domain of DEAD-like helicase Snf family proteins; Sucrose Non-Fermenting ... |
1074-1322 |
2.95e-06 |
|
DEXH/Q-box helicase domain of DEAD-like helicase Snf family proteins; Sucrose Non-Fermenting (SNF) proteins DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350677 [Multi-domain] Cd Length: 182 Bit Score: 49.49 E-value: 2.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1074 LKPHQKNAVARILM----GGNTLLAHCVGAGKSFEMMSACMEQKRLGLANKTVMVV-PKSLIGQTASEFLRLYPSANILV 1148
Cdd:cd17919 1 LRPYQLEGLNFLLElyenGPGGILADEMGLGKTLQAIAFLAYLLKEGKERGPVLVVcPLSVLENWEREFEKWTPDLRVVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1149 ATErdfEKSRRKQFISRIATGDYDCIIMSHSqfekipisaerkkaMIDRQIEEisysitemkarngerwtikqmeaqkkk 1228
Cdd:cd17919 81 YHG---SQRERAQIRAKEKLDKFDVVLTTYE--------------TLRRDKAS--------------------------- 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1229 leeqireltdesrkddlitFEELGIDSIMVDEAHGFKNLAifSKMNNVAgisstgskkatdMQMKCQYiselnggrgIVF 1308
Cdd:cd17919 117 -------------------LRKFRWDLVVVDEAHRLKNPK--SQLSKAL------------KALRAKR---------RLL 154
|
250
....*....|....
gi 2744976818 1309 ATGTPISNTMCELY 1322
Cdd:cd17919 155 LTGTPLQNNLEELW 168
|
|
| ResIII |
pfam04851 |
Type III restriction enzyme, res subunit; |
1071-1168 |
2.15e-05 |
|
Type III restriction enzyme, res subunit;
Pssm-ID: 398492 [Multi-domain] Cd Length: 162 Bit Score: 46.51 E-value: 2.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1071 KIELKPHQKNAVARILMG-----GNTLLAHCVGAGKSFEMMSACMEQKRLGLANKTVMVVP-KSLIGQTASEFLRLYPSA 1144
Cdd:pfam04851 1 KLELRPYQIEAIENLLESikngqKRGLIVMATGSGKTLTAAKLIARLFKKGPIKKVLFLVPrKDLLEQALEEFKKFLPNY 80
|
90 100
....*....|....*....|....*...
gi 2744976818 1145 ----NILVATERDFEKSRRKQFISRIAT 1168
Cdd:pfam04851 81 veigEIISGDKKDESVDDNKIVVTTIQS 108
|
|
| DEXDc_SHPRH-like |
cd18008 |
DEXH-box helicase domain of SHPRH-like proteins; The SHPRH-like subgroup belongs to the ... |
1074-1344 |
6.63e-05 |
|
DEXH-box helicase domain of SHPRH-like proteins; The SHPRH-like subgroup belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350766 [Multi-domain] Cd Length: 241 Bit Score: 46.51 E-value: 6.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1074 LKPHQKNAVARILM-GGntLLAHCVGAGKSFEM------------------MSACMEQKRLGLANKTVMVVPKSLIGQTA 1134
Cdd:cd18008 1 LLPYQKQGLAWMLPrGG--ILADEMGLGKTIQAlalilatrpqdpkipeelEENSSDPKKLYLSKTTLIVVPLSLLSQWK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1135 SEFLR--LYPSANILVaterdFEKSRRKQFISRIAtgDYDCIIMSHSQFEKiPISAERKKAMIDRQIEEIS--YSItemk 1210
Cdd:cd18008 79 DEIEKhtKPGSLKVYV-----YHGSKRIKSIEELS--DYDIVITTYGTLAS-EFPKNKKGGGRDSKEKEASplHRI---- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1211 arngeRWtikqmeaqkkkleeqireltdeSRkddlitfeelgidsIMVDEAHGFKNlaifskmnnvagISSTGSKKATDM 1290
Cdd:cd18008 147 -----RW----------------------YR--------------VILDEAHNIKN------------RSTKTSRAVCAL 173
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 2744976818 1291 QMKCqyiselnggRGIVfaTGTPISNTMCELYVMqlylqrekLEQMGIYHFDAW 1344
Cdd:cd18008 174 KAER---------RWCL--TGTPIQNSLDDLYSL--------LRFLRVEPFGDY 208
|
|
| DEXHc_RAD54 |
cd18004 |
DEXH-box helicase domain of RAD54; RAD54 proteins play a role in recombination. They are ... |
1074-1181 |
6.76e-05 |
|
DEXH-box helicase domain of RAD54; RAD54 proteins play a role in recombination. They are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350762 [Multi-domain] Cd Length: 240 Bit Score: 46.51 E-value: 6.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1074 LKPHQKNAV---------ARILMGGNTLLAHCVGAGKSFE---MMSACMEQKRLG--LANKTVMVVPKSLIGQTASEFLR 1139
Cdd:cd18004 1 LRPHQREGVqflydcltgRRGYGGGGAILADEMGLGKTLQaiaLVWTLLKQGPYGkpTAKKALIVCPSSLVGNWKAEFDK 80
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2744976818 1140 LYPSANILVATERDFEKSRRKQFISRIATGDYDCIIMSHSQF 1181
Cdd:cd18004 81 WLGLRRIKVVTADGNAKDVKASLDFFSSASTYPVLIISYETL 122
|
|
| DEXQc_arch_SWI2_SNF2 |
cd18012 |
DEAQ-box helicase domain of archaeal and bacterial SNF2-related proteins; Proteins belonging ... |
1073-1177 |
1.96e-04 |
|
DEAQ-box helicase domain of archaeal and bacterial SNF2-related proteins; Proteins belonging to SNF2 family of DNA dependent ATPases are important members of the chromatin remodeling complexes that are implicated in epigenetic control of gene expression. The Snf2 family comprises a large group of ATP-hydrolyzing proteins that are ubiquitous in eukaryotes, but also present in eubacteria and archaea. Archaeal SWI2 and SNF2 are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350770 [Multi-domain] Cd Length: 218 Bit Score: 44.86 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1073 ELKPHQKNAV----ARILMGGNTLLAHCVGAGKSFEMMSACMEQKRLGLANKTVMVVPKSLIGQTASEFLRLYPSANILV 1148
Cdd:cd18012 4 TLRPYQKEGFnwlsFLRHYGLGGILADDMGLGKTLQTLALLLSRKEEGRKGPSLVVAPTSLIYNWEEEAAKFAPELKVLV 83
|
90 100
....*....|....*....|....*....
gi 2744976818 1149 aterdFEKSRRKQFISRIAtGDYDCIIMS 1177
Cdd:cd18012 84 -----IHGTKRKREKLRAL-EDYDLVITS 106
|
|
| DEXDc_RapA |
cd18011 |
DEXH-box helicase domain of RapA; In bacteria, RapA is an RNA polymerase (RNAP)-associated ... |
1074-1132 |
4.53e-04 |
|
DEXH-box helicase domain of RapA; In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350769 [Multi-domain] Cd Length: 207 Bit Score: 43.43 E-value: 4.53e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2744976818 1074 LKPHQKNAVARILMGGNT--LLAHCVGAGKSFEMMSACMEQKRLGLANKTVMVVPKSLIGQ 1132
Cdd:cd18011 1 PLPHQIDAVLRALRKPPVrlLLADEVGLGKTIEAGLIIKELLLRGDAKRVLILCPASLVEQ 61
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
1088-1183 |
1.02e-03 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 41.62 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1088 GGNTLLAHCVGAGKSFEMMSAcMEQKRLGLANKTVMVVP-KSLIGQTASEFLRLYpSANILVATERDFEKSRRKqfiSRI 1166
Cdd:cd00046 1 GENVLITAPTGSGKTLAALLA-ALLLLLKKGKKVLVLVPtKALALQTAERLRELF-GPGIRVAVLVGGSSAEER---EKN 75
|
90
....*....|....*..
gi 2744976818 1167 ATGDYDCIIMSHSQFEK 1183
Cdd:cd00046 76 KLGDADIIIATPDMLLN 92
|
|
| SNF2-rel_dom |
pfam00176 |
SNF2-related domain; This domain is found in proteins involved in a variety of processes ... |
1077-1139 |
1.95e-03 |
|
SNF2-related domain; This domain is found in proteins involved in a variety of processes including transcription regulation (e.g., SNF2, STH1, brahma, MOT1), DNA repair (e.g., ERCC6, RAD16, RAD5), DNA recombination (e.g., RAD54), and chromatin unwinding (e.g., ISWI) as well as a variety of other proteins with little functional information (e.g., lodestar, ETL1). SNF2 functions as the ATPase component of the SNF2/SWI multisubunit complex, which utilizes energy derived from ATP hydrolysis to disrupt histone-DNA interactions, resulting in the increased accessibility of DNA to transcription factors.
Pssm-ID: 425504 [Multi-domain] Cd Length: 289 Bit Score: 42.29 E-value: 1.95e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2744976818 1077 HQKNAVARIL-----MGGNTLLAHCVGAGKSFEMMS---ACMEQKRLgLANKTVMVVPKSLIGQTASEFLR 1139
Cdd:pfam00176 1 YQIEGVNWMLslennLGRGGILADEMGLGKTLQTISlllYLKHVDKN-WGGPTLIVVPLSLLHNWMNEFER 70
|
|
| N6_Mtase |
pfam02384 |
N-6 DNA Methylase; Restriction-modification (R-M) systems protect a bacterial cell against ... |
337-537 |
3.81e-03 |
|
N-6 DNA Methylase; Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.
Pssm-ID: 426749 [Multi-domain] Cd Length: 310 Bit Score: 41.54 E-value: 3.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 337 YAAARATVNNAFYT-SPVICTCINRALVSFGFhggNLLEPSMGTGNFF-------GSLPASMRSANLYGVELDSISGRIA 408
Cdd:pfam02384 16 FAPNAGKSGGEFFTpREVSKLIVELLDPKPGE---SIYDPACGSGGFLiqaekfvKEHDGDTNDLSIYGQEKNPTTYRLA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 409 K-QLY----QTANITIGGFEHTEYP----DNFFDVAVGNVPFGDyKVFDKKYNKYNFRIHDY------------FLAKAL 467
Cdd:pfam02384 93 RmNMIlhgiEYDDFHIRHGDTLTSPkfedDKKFDVVVANPPFSD-KWDANDTLENDPRFRPAygvapksnadlaFLQHII 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2744976818 468 DQVRPGGIVAFVTTKGTLDKSNP--AIRQYLAQRAELIGAVRLPNTAFKdnaGTEVTCDILFLQK--RERKMDV 537
Cdd:pfam02384 172 YYLAPGGRAAVVLPNGVLFRGGAegKIRKALVDKDLVETVIALPPNLFY---NTSIPTCILFLTKnkAERKGKV 242
|
|
| DEXHc_SMARCA1_SMARCA5 |
cd17997 |
DEAH-box helicase domain of SMARCA1 and SMARCA5; SWI/SNF related, matrix associated, actin ... |
1054-1178 |
9.50e-03 |
|
DEAH-box helicase domain of SMARCA1 and SMARCA5; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 and 5 (SMARCA1 and SMARCA5) are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350755 [Multi-domain] Cd Length: 222 Bit Score: 39.61 E-value: 9.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1054 RLREYdgsylQFPGMNPKIELkphQKNavarilmGGNTLLAHCVGAGKSFEMMS--ACMEQKRlGLANKTVMVVPKSLIG 1131
Cdd:cd17997 3 TMRDY-----QIRGLNWLISL---FEN-------GINGILADEMGLGKTLQTISllGYLKHYK-NINGPHLIIVPKSTLD 66
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2744976818 1132 QTASEFLRLYPSANILV--ATERDfeksrRKQFI-SRIATGDYDCIIMSH 1178
Cdd:cd17997 67 NWMREFKRWCPSLRVVVliGDKEE-----RADIIrDVLLPGKFDVCITSY 111
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
378-498 |
9.90e-03 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 38.44 E-value: 9.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2744976818 378 GTGNFfgSLPASMRSANLYGVELDSISGRIAKQLYQTANITI----GGFEHTEYPDNFFDVAVGNVPFgdykvfdkkynk 453
Cdd:COG2226 32 GTGRL--ALALAERGARVTGVDISPEMLELARERAAEAGLNVefvvGDAEDLPFPDGSFDLVISSFVL------------ 97
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2744976818 454 YNFRIHDYFLAKALDQVRPGGIVAFVTTKGTldkSNPAIRQYLAQ 498
Cdd:COG2226 98 HHLPDPERALAEIARVLKPGGRLVVVDFSPP---DLAELEELLAE 139
|
|
| |
