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Conserved domains on  [gi|2747583657|ref|WP_350669763|]
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hypothetical protein, partial [Pseudoalteromonas sp. 43-MNA-CIBAN-0464]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
malate_synt super family cl21481
Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , ...
 1-68 4.02e-26

Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.


The actual alignment was detected with superfamily member PRK02999:

Pssm-ID: 451263 [Multi-domain]  Cd Length: 726  Bit Score: 98.70  E-value: 4.02e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2747583657   1 MSHTLTHSGLSVDKQLAEFVKKQLLPGTHLDEHQFWKNFAHIVQTLTPLNKSLLAKREQLQKQIDDYH 68
Cdd:PRK02999    1 MTERVQVGGLQVAAVLYDFVNNEALPGTGVDADAFWAGFAAIVHDLAPKNRALLAKRDELQAKIDAWH 68
 
Name Accession Description Interval E-value
PRK02999 PRK02999
malate synthase G; Provisional
 1-68 4.02e-26

malate synthase G; Provisional


Pssm-ID: 235097 [Multi-domain]  Cd Length: 726  Bit Score: 98.70  E-value: 4.02e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2747583657   1 MSHTLTHSGLSVDKQLAEFVKKQLLPGTHLDEHQFWKNFAHIVQTLTPLNKSLLAKREQLQKQIDDYH 68
Cdd:PRK02999    1 MTERVQVGGLQVAAVLYDFVNNEALPGTGVDADAFWAGFAAIVHDLAPKNRALLAKRDELQAKIDAWH 68
malate_synt_G cd00728
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
 9-68 1.14e-20

Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.


Pssm-ID: 238370 [Multi-domain]  Cd Length: 712  Bit Score: 83.23  E-value: 1.14e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2747583657   9 GLSVDKQLAEFVKKQLLPGTHLDEHQFWKNFAHIVQTLTPLNKSLLAKREQLQKQIDDYH 68
Cdd:cd00728     1 NLRVAGCLYDFVNEEALPGTGIDADAFWAGFDEIVHDLTPRNRALLAKRDELQAKIDDWH 60
Malate_synthase pfam01274
Malate synthase;
18-68 1.98e-11

Malate synthase;


Pssm-ID: 426172  Cd Length: 523  Bit Score: 57.02  E-value: 1.98e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2747583657  18 EFVKKQLLPGTHLDEHQFWKNFAHIVQTLTPLNKSLLAKREQLQKQIDDYH 68
Cdd:pfam01274   2 DFVGPYVLPGTGILTKEALSFVAELHRDFTPRRRELLARRDERQARIDAGH 52
 
Name Accession Description Interval E-value
PRK02999 PRK02999
malate synthase G; Provisional
 1-68 4.02e-26

malate synthase G; Provisional


Pssm-ID: 235097 [Multi-domain]  Cd Length: 726  Bit Score: 98.70  E-value: 4.02e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2747583657   1 MSHTLTHSGLSVDKQLAEFVKKQLLPGTHLDEHQFWKNFAHIVQTLTPLNKSLLAKREQLQKQIDDYH 68
Cdd:PRK02999    1 MTERVQVGGLQVAAVLYDFVNNEALPGTGVDADAFWAGFAAIVHDLAPKNRALLAKRDELQAKIDAWH 68
malate_synt_G cd00728
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
 9-68 1.14e-20

Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.


Pssm-ID: 238370 [Multi-domain]  Cd Length: 712  Bit Score: 83.23  E-value: 1.14e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2747583657   9 GLSVDKQLAEFVKKQLLPGTHLDEHQFWKNFAHIVQTLTPLNKSLLAKREQLQKQIDDYH 68
Cdd:cd00728     1 NLRVAGCLYDFVNEEALPGTGIDADAFWAGFDEIVHDLTPRNRALLAKRDELQAKIDDWH 60
Malate_synthase pfam01274
Malate synthase;
18-68 1.98e-11

Malate synthase;


Pssm-ID: 426172  Cd Length: 523  Bit Score: 57.02  E-value: 1.98e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2747583657  18 EFVKKQLLPGTHLDEHQFWKNFAHIVQTLTPLNKSLLAKREQLQKQIDDYH 68
Cdd:pfam01274   2 DFVGPYVLPGTGILTKEALSFVAELHRDFTPRRRELLARRDERQARIDAGH 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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