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Conserved domains on  [gi|2689246662|gb|WWP54673|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Lagopus lagopus alascensis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.28e-56

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 175.32  E-value: 1.28e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662   1 MTYFVIIIGVCFMLGVLAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  81 AWGDWRVVGYGLGFV-SVVCVGAVLGGFVDFWKVGVTTIDGGGVSFVRLDMSGVAVFYSWGVGLFLVAGWGLLLALFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVlVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2689246662 160 ELVRGLSRGAIRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.28e-56

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 175.32  E-value: 1.28e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662   1 MTYFVIIIGVCFMLGVLAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  81 AWGDWRVVGYGLGFV-SVVCVGAVLGGFVDFWKVGVTTIDGGGVSFVRLDMSGVAVFYSWGVGLFLVAGWGLLLALFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVlVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2689246662 160 ELVRGLSRGAIRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 2.20e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.59  E-value: 2.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  17 LAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSL-AADPYPEAWGDWRVVGYGLGFV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2689246662  96 SVVcvgaVLGGFVDFWKVGVTTIDGGGVSFVRLDMSGVAVFYSWGVgLFLVAGWGLLLALFVVLEL 161
Cdd:pfam00499  81 LLL----ALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.28e-56

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 175.32  E-value: 1.28e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662   1 MTYFVIIIGVCFMLGVLAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  81 AWGDWRVVGYGLGFV-SVVCVGAVLGGFVDFWKVGVTTIDGGGVSFVRLDMSGVAVFYSWGVGLFLVAGWGLLLALFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVlVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2689246662 160 ELVRGLSRGAIRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.21e-55

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 173.02  E-value: 1.21e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662   1 MTYFVIIIGVCFMLGVLAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  81 AWGDWRVVGYGLGFVSVVCVGAVL--GGFVDFWKVGVTtiDGGGVSFVRLDMSGVAVFYSWGVGLFLVAGWGLLLALFVV 158
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLfwGGWYEGSWVVVD--ELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVV 158

                         170
                  ....*....|....*
gi 2689246662 159 LELVRGLSRGAIRAV 173
Cdd:MTH00138  159 LELTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 2.38e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 159.63  E-value: 2.38e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662   1 MTYFVIIIGVCFMLGVLAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  81 AWGDWRVVGYGLGFVSVVCVGAVLGGFVDFwKVGVTTIDGGGVSFVRLDMSGVAVFYSWGVGLFLVAGWGLLLALFVVLE 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFS-LEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                         170
                  ....*....|...
gi 2689246662 161 LVRGLSRGAIRAV 173
Cdd:MTH00065  160 VTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-164 2.18e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 103.34  E-value: 2.18e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662   1 MTYFVIIIGVCFMLGVLAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  81 AWGDWRVVGYGL---GFVSVVCVGAVLGGF-----VDFWKVGVTTI-DGGGVSFVRLDMSGVAVFYSWGVGLFLVAGWGL 151
Cdd:MTH00109   82 TWVSNKVVLGALllgLLMELLLVLYVLKDDevevvFNFNGLGDWVIyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 2689246662 152 LLALFVVLELVRG 164
Cdd:MTH00109  162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 2.17e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 95.44  E-value: 2.17e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662   1 MTYFVIIIGVCFMLGVLAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  81 AWGDWRVVGYGLGFVSVVCVGAVLGGFVDFWKVGVttidgGGVSFVRLDMSGVAVFYSWGVGLFLVAGWGLLLALFVVLE 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWM-----GVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                         170
                  ....*....|...
gi 2689246662 161 LVRGLSRGAIRAV 173
Cdd:MTH00214  156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 7-172 2.11e-15

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 69.55  E-value: 2.11e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662   7 IIGVCFMLGVLAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSLAADPYPEAWGDWR 86
Cdd:MTH00045    5 LFLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  87 VVgyGLGFVSVVCVGAVLGGFVDFWKVGVTTIDGggvsfvrLDMSGVAVFYSWGVGLFLVAGWGLLLALFVVLELVRGLS 166
Cdd:MTH00045   85 VL--VLSLLLSLWVFISFDNFLELSNNNWSLVSL-------SDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHE 155


                  ....*.
gi 2689246662 167 RGAIRA 172
Cdd:MTH00045  156 YSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 2.20e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.59  E-value: 2.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2689246662  17 LAVASNPSPYYGVVGLVLASVMGCGWLVNLGVSFISLSLFMIYLGGMLVVFVYSVSL-AADPYPEAWGDWRVVGYGLGFV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2689246662  96 SVVcvgaVLGGFVDFWKVGVTTIDGGGVSFVRLDMSGVAVFYSWGVgLFLVAGWGLLLALFVVLEL 161
Cdd:pfam00499  81 LLL----ALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 49-74 5.74e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 35.55  E-value: 5.74e-03
                          10        20
                  ....*....|....*....|....*.
gi 2689246662  49 SFISLSLFMIYLGGMLVVFVYSVSLA 74
Cdd:MTH00166   46 FWFSYILFLIFLGGMLVLFIYITSLA 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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