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Conserved domains on  [gi|330843113|ref|XP_003293507|]
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uncharacterized protein DICPUDRAFT_84058 [Dictyostelium purpureum]

Protein Classification

ribonuclease P Rpr2/Rpp21/SNM1 subunit family protein( domain architecture ID 2956)

ribonuclease P Rpr2/Rpp21/SNM1 subunit family protein such as ribonuclease P protein component 4, which is part of RNAse P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends

EC:  3.1.26.5
Gene Ontology:  GO:0004526|GO:0046872

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rpr2 super family cl00887
RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of ...
 11-37 6.48e-04

RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of humans and yeast. Other members of the family include the probable archaeal homologs. This family includes SNM1. It is a subunit of RNase MRP (mitochondrial RNA processing), a ribonucleoprotein endoribonuclease that has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing. SNM1 is an RNA binding protein that binds the MRP RNA specifically. This subunit possibly binds the precursor tRNA.


The actual alignment was detected with superfamily member COG2023:

Pssm-ID: 469974  Cd Length: 90  Bit Score: 37.12  E-value: 6.48e-04
                         10        20
                 ....*....|....*....|....*..
gi 330843113  11 PTMIESRNCRiNCGTFLIPGINCRVRI 37
Cdd:COG2023   44 PRELKRRFCK-KCDAPLVPGVNARVRL 69
 
Name Accession Description Interval E-value
RPR2 COG2023
Ribonuclease P protein subunit RPR2 [Translation, ribosomal structure and biogenesis];
11-37 6.48e-04

Ribonuclease P protein subunit RPR2 [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441626  Cd Length: 90  Bit Score: 37.12  E-value: 6.48e-04
                         10        20
                 ....*....|....*....|....*..
gi 330843113  11 PTMIESRNCRiNCGTFLIPGINCRVRI 37
Cdd:COG2023   44 PRELKRRFCK-KCDAPLVPGVNARVRL 69
Rpr2 pfam04032
RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of ...
 19-49 5.50e-03

RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of humans and yeast. Other members of the family include the probable archaeal homologs. This family includes SNM1. It is a subunit of RNase MRP (mitochondrial RNA processing), a ribonucleoprotein endoribonuclease that has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing. SNM1 is an RNA binding protein that binds the MRP RNA specifically. This subunit possibly binds the precursor tRNA.


Pssm-ID: 427665  Cd Length: 88  Bit Score: 34.58  E-value: 5.50e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 330843113   19 CRiNCGTFLIPGINCRVRIIKTDQLSNKSRS 49
Cdd:pfam04032  48 CK-KCGTLLIPGVTCTVRIENKSKGGKKPWA 77
 
Name Accession Description Interval E-value
RPR2 COG2023
Ribonuclease P protein subunit RPR2 [Translation, ribosomal structure and biogenesis];
11-37 6.48e-04

Ribonuclease P protein subunit RPR2 [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441626  Cd Length: 90  Bit Score: 37.12  E-value: 6.48e-04
                         10        20
                 ....*....|....*....|....*..
gi 330843113  11 PTMIESRNCRiNCGTFLIPGINCRVRI 37
Cdd:COG2023   44 PRELKRRFCK-KCDAPLVPGVNARVRL 69
Rpr2 pfam04032
RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of ...
 19-49 5.50e-03

RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of humans and yeast. Other members of the family include the probable archaeal homologs. This family includes SNM1. It is a subunit of RNase MRP (mitochondrial RNA processing), a ribonucleoprotein endoribonuclease that has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing. SNM1 is an RNA binding protein that binds the MRP RNA specifically. This subunit possibly binds the precursor tRNA.


Pssm-ID: 427665  Cd Length: 88  Bit Score: 34.58  E-value: 5.50e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 330843113   19 CRiNCGTFLIPGINCRVRIIKTDQLSNKSRS 49
Cdd:pfam04032  48 CK-KCGTLLIPGVTCTVRIENKSKGGKKPWA 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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