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Conserved domains on  [gi|470239423|ref|XP_004351477|]
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bystin [Cavenderia fasciculata]

Protein Classification

bystin family protein( domain architecture ID 10526307)

bystin family protein similar to human bystin that is required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bystin pfam05291
Bystin; Trophinin and tastin form a cell adhesion molecule complex that potentially mediates ...
 206-484 8.52e-154

Bystin; Trophinin and tastin form a cell adhesion molecule complex that potentially mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of implantation. Trophinin and tastin bind to an intermediary cytoplasmic protein called bystin. Bystin may be involved in implantation and trophoblast invasion because bystin is found with trophinin and tastin in the cells at human implantation sites and also in the intermediate trophoblasts at invasion front in the placenta from early pregnancy. This family also includes the yeast protein ENP1. ENP1 is an essential protein in Saccharomyces cerevisiae and is localized in the nucleus. It is thought that ENP1 plays a direct role in the early steps of rRNA processing as enp1 defective yeast cannot synthesize 20S pre-rRNA and hence 18S rRNA, which leads to reduced formation of 40S ribosomal subunits.


:

Pssm-ID: 461612  Cd Length: 290  Bit Score: 439.25  E-value: 8.52e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470239423  206 RFTLGQLIEAKLKEQEEKESMV------KEPRQKMNPKVLEVYKKVGQMLAHYRSGKVPRAFCILPNFTNWEDLIYLTRP 279
Cdd:pfam05291   1 RRTLADLILEKIAEKEAEQSSQlsdggpPEEPVELDPKVVEVYTKVGELLSRYKSGKLPKAFKIIPSLPNWEDLLYLTEP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470239423  280 DLWTPHAVREATKIFVMSSNARQTQRFLSLVLLPRVRDNIAEFRKLNFHLYMALKKSLYRPQAFYKAIFLPLAEEGDATL 359
Cdd:pfam05291  81 ENWTPHAMYEATRIFVSNLKAKQAQRFYELVLLPRVRDDIRENKKLNVHLYNALKKALYKPAAFFKGILFPLCESGTCTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470239423  360 LEAKIIASVVKKVSVPVIHSSVALLKLAQIPkYNGATSLFIMTLCDKKYSLPLRVVDSLYQHFISFV-DERRDLPVLWHQ 438
Cdd:pfam05291 161 REAVIIGSVLAKVSIPVLHSAAALLKLAEME-YSGATSIFIRVLLDKKYALPYRVVDALVFHFLRFRnDTPRELPVLWHQ 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 470239423  439 SLLMFVQRYKNDIKPQHKENLKILLRNQFHHQITNEIRRELFNNQS 484
Cdd:pfam05291 240 SLLVFAQRYKNDITEDQKEALLDLLRVQGHHQITPEIRRELLASRG 285
 
Name Accession Description Interval E-value
Bystin pfam05291
Bystin; Trophinin and tastin form a cell adhesion molecule complex that potentially mediates ...
 206-484 8.52e-154

Bystin; Trophinin and tastin form a cell adhesion molecule complex that potentially mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of implantation. Trophinin and tastin bind to an intermediary cytoplasmic protein called bystin. Bystin may be involved in implantation and trophoblast invasion because bystin is found with trophinin and tastin in the cells at human implantation sites and also in the intermediate trophoblasts at invasion front in the placenta from early pregnancy. This family also includes the yeast protein ENP1. ENP1 is an essential protein in Saccharomyces cerevisiae and is localized in the nucleus. It is thought that ENP1 plays a direct role in the early steps of rRNA processing as enp1 defective yeast cannot synthesize 20S pre-rRNA and hence 18S rRNA, which leads to reduced formation of 40S ribosomal subunits.


Pssm-ID: 461612  Cd Length: 290  Bit Score: 439.25  E-value: 8.52e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470239423  206 RFTLGQLIEAKLKEQEEKESMV------KEPRQKMNPKVLEVYKKVGQMLAHYRSGKVPRAFCILPNFTNWEDLIYLTRP 279
Cdd:pfam05291   1 RRTLADLILEKIAEKEAEQSSQlsdggpPEEPVELDPKVVEVYTKVGELLSRYKSGKLPKAFKIIPSLPNWEDLLYLTEP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470239423  280 DLWTPHAVREATKIFVMSSNARQTQRFLSLVLLPRVRDNIAEFRKLNFHLYMALKKSLYRPQAFYKAIFLPLAEEGDATL 359
Cdd:pfam05291  81 ENWTPHAMYEATRIFVSNLKAKQAQRFYELVLLPRVRDDIRENKKLNVHLYNALKKALYKPAAFFKGILFPLCESGTCTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470239423  360 LEAKIIASVVKKVSVPVIHSSVALLKLAQIPkYNGATSLFIMTLCDKKYSLPLRVVDSLYQHFISFV-DERRDLPVLWHQ 438
Cdd:pfam05291 161 REAVIIGSVLAKVSIPVLHSAAALLKLAEME-YSGATSIFIRVLLDKKYALPYRVVDALVFHFLRFRnDTPRELPVLWHQ 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 470239423  439 SLLMFVQRYKNDIKPQHKENLKILLRNQFHHQITNEIRRELFNNQS 484
Cdd:pfam05291 240 SLLVFAQRYKNDITEDQKEALLDLLRVQGHHQITPEIRRELLASRG 285
 
Name Accession Description Interval E-value
Bystin pfam05291
Bystin; Trophinin and tastin form a cell adhesion molecule complex that potentially mediates ...
 206-484 8.52e-154

Bystin; Trophinin and tastin form a cell adhesion molecule complex that potentially mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of implantation. Trophinin and tastin bind to an intermediary cytoplasmic protein called bystin. Bystin may be involved in implantation and trophoblast invasion because bystin is found with trophinin and tastin in the cells at human implantation sites and also in the intermediate trophoblasts at invasion front in the placenta from early pregnancy. This family also includes the yeast protein ENP1. ENP1 is an essential protein in Saccharomyces cerevisiae and is localized in the nucleus. It is thought that ENP1 plays a direct role in the early steps of rRNA processing as enp1 defective yeast cannot synthesize 20S pre-rRNA and hence 18S rRNA, which leads to reduced formation of 40S ribosomal subunits.


Pssm-ID: 461612  Cd Length: 290  Bit Score: 439.25  E-value: 8.52e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470239423  206 RFTLGQLIEAKLKEQEEKESMV------KEPRQKMNPKVLEVYKKVGQMLAHYRSGKVPRAFCILPNFTNWEDLIYLTRP 279
Cdd:pfam05291   1 RRTLADLILEKIAEKEAEQSSQlsdggpPEEPVELDPKVVEVYTKVGELLSRYKSGKLPKAFKIIPSLPNWEDLLYLTEP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470239423  280 DLWTPHAVREATKIFVMSSNARQTQRFLSLVLLPRVRDNIAEFRKLNFHLYMALKKSLYRPQAFYKAIFLPLAEEGDATL 359
Cdd:pfam05291  81 ENWTPHAMYEATRIFVSNLKAKQAQRFYELVLLPRVRDDIRENKKLNVHLYNALKKALYKPAAFFKGILFPLCESGTCTL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470239423  360 LEAKIIASVVKKVSVPVIHSSVALLKLAQIPkYNGATSLFIMTLCDKKYSLPLRVVDSLYQHFISFV-DERRDLPVLWHQ 438
Cdd:pfam05291 161 REAVIIGSVLAKVSIPVLHSAAALLKLAEME-YSGATSIFIRVLLDKKYALPYRVVDALVFHFLRFRnDTPRELPVLWHQ 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 470239423  439 SLLMFVQRYKNDIKPQHKENLKILLRNQFHHQITNEIRRELFNNQS 484
Cdd:pfam05291 240 SLLVFAQRYKNDITEDQKEALLDLLRVQGHHQITPEIRRELLASRG 285
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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