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Conserved domains on  [gi|530369823|ref|XP_005246360|]
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spermatogenesis-associated protein 3 isoform X2 [Homo sapiens]

Protein Classification

SPATA3 domain-containing protein( domain architecture ID 12174177)

SPATA3 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SPATA3 pfam15662
Spermatogenesis-associated protein 3 family; The SPATA3 family of proteins is expressed ...
 1-191 6.19e-81

Spermatogenesis-associated protein 3 family; The SPATA3 family of proteins is expressed significantly in testis and faintly in epididymis in the ten tissues of testis, ovary, spleen, kidney, lung, heart, brain, epididymis, liver and skeletal muscle in mouse. Members are not expressed in the eight other tissues. This suggests that SPATA3 plays potential roles in spermatogenesis cell apoptosis or spermatogenesis.


:

Pssm-ID: 434837 [Multi-domain]  Cd Length: 190  Bit Score: 238.72  E-value: 6.19e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823    1 MKKVKKKRSEARRHRDSTSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSlETTSRQPAFQALPAPEIRRS 80
Cdd:pfam15662   1 MKKVKKKKSESRRHRGSTSQHASSESTPQQPSSESAPQQPSPESTPQQPSPSTTPQPSS-ESTPQQPASQALPAPEIRHS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823   81 SCCLLSPDANVKAAPQSRKAGPLIRAGPHSCSCATCPCSSACWRRLGLCHSRIFDVLLPRDWQMAPGRGLPNLLTFYRKS 160
Cdd:pfam15662  80 SRCLLPPDPNTKAAPPSRKAGPLTYAGPRSCSCAACPGSSACWRRLGLCHSRIFDVLLPRDWQLMPGRGIPSLLTFYRKP 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 530369823  161 SRKPSSHRNACPPSPRNCGCGSGGSRSCLLH 191
Cdd:pfam15662 160 SRKHSSHRNSRAPSSRDCCCGSGGPGSCLLH 190
 
Name Accession Description Interval E-value
SPATA3 pfam15662
Spermatogenesis-associated protein 3 family; The SPATA3 family of proteins is expressed ...
 1-191 6.19e-81

Spermatogenesis-associated protein 3 family; The SPATA3 family of proteins is expressed significantly in testis and faintly in epididymis in the ten tissues of testis, ovary, spleen, kidney, lung, heart, brain, epididymis, liver and skeletal muscle in mouse. Members are not expressed in the eight other tissues. This suggests that SPATA3 plays potential roles in spermatogenesis cell apoptosis or spermatogenesis.


Pssm-ID: 434837 [Multi-domain]  Cd Length: 190  Bit Score: 238.72  E-value: 6.19e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823    1 MKKVKKKRSEARRHRDSTSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSlETTSRQPAFQALPAPEIRRS 80
Cdd:pfam15662   1 MKKVKKKKSESRRHRGSTSQHASSESTPQQPSSESAPQQPSPESTPQQPSPSTTPQPSS-ESTPQQPASQALPAPEIRHS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823   81 SCCLLSPDANVKAAPQSRKAGPLIRAGPHSCSCATCPCSSACWRRLGLCHSRIFDVLLPRDWQMAPGRGLPNLLTFYRKS 160
Cdd:pfam15662  80 SRCLLPPDPNTKAAPPSRKAGPLTYAGPRSCSCAACPGSSACWRRLGLCHSRIFDVLLPRDWQLMPGRGIPSLLTFYRKP 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 530369823  161 SRKPSSHRNACPPSPRNCGCGSGGSRSCLLH 191
Cdd:pfam15662 160 SRKHSSHRNSRAPSSRDCCCGSGGPGSCLLH 190
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 3-80 7.76e-05

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 42.69  E-value: 7.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823   3 KVKKKRSEARR------HRDSTSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSLETTSRQPAFQALPAPE 76
Cdd:NF033838 377 KVESKKAEATRlekiktDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAEQPKAEKPADQQAEEDY 456


                 ....
gi 530369823  77 IRRS 80
Cdd:NF033838 457 ARRS 460
PRK08581 PRK08581
amidase domain-containing protein;
16-68 5.84e-04

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 39.77  E-value: 5.84e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 530369823  16 DSTSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSLETTSRQPA 68
Cdd:PRK08581 169 DKADNQKAPSSNNTKPSTSNKQPNSPKPTQPNQSNSQPASDDTANQKSSSKDN 221
 
Name Accession Description Interval E-value
SPATA3 pfam15662
Spermatogenesis-associated protein 3 family; The SPATA3 family of proteins is expressed ...
 1-191 6.19e-81

Spermatogenesis-associated protein 3 family; The SPATA3 family of proteins is expressed significantly in testis and faintly in epididymis in the ten tissues of testis, ovary, spleen, kidney, lung, heart, brain, epididymis, liver and skeletal muscle in mouse. Members are not expressed in the eight other tissues. This suggests that SPATA3 plays potential roles in spermatogenesis cell apoptosis or spermatogenesis.


Pssm-ID: 434837 [Multi-domain]  Cd Length: 190  Bit Score: 238.72  E-value: 6.19e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823    1 MKKVKKKRSEARRHRDSTSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSlETTSRQPAFQALPAPEIRRS 80
Cdd:pfam15662   1 MKKVKKKKSESRRHRGSTSQHASSESTPQQPSSESAPQQPSPESTPQQPSPSTTPQPSS-ESTPQQPASQALPAPEIRHS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823   81 SCCLLSPDANVKAAPQSRKAGPLIRAGPHSCSCATCPCSSACWRRLGLCHSRIFDVLLPRDWQMAPGRGLPNLLTFYRKS 160
Cdd:pfam15662  80 SRCLLPPDPNTKAAPPSRKAGPLTYAGPRSCSCAACPGSSACWRRLGLCHSRIFDVLLPRDWQLMPGRGIPSLLTFYRKP 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 530369823  161 SRKPSSHRNACPPSPRNCGCGSGGSRSCLLH 191
Cdd:pfam15662 160 SRKHSSHRNSRAPSSRDCCCGSGGPGSCLLH 190
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 3-80 7.76e-05

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 42.69  E-value: 7.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823   3 KVKKKRSEARR------HRDSTSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSLETTSRQPAFQALPAPE 76
Cdd:NF033838 377 KVESKKAEATRlekiktDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAEQPKAEKPADQQAEEDY 456


                 ....
gi 530369823  77 IRRS 80
Cdd:NF033838 457 ARRS 460
PRK08581 PRK08581
amidase domain-containing protein;
16-68 5.84e-04

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 39.77  E-value: 5.84e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 530369823  16 DSTSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSLETTSRQPA 68
Cdd:PRK08581 169 DKADNQKAPSSNNTKPSTSNKQPNSPKPTQPNQSNSQPASDDTANQKSSSKDN 221
PLN03029 PLN03029
type-a response regulator protein; Provisional
 1-62 1.19e-03

type-a response regulator protein; Provisional


Pssm-ID: 215544 [Multi-domain]  Cd Length: 222  Bit Score: 38.48  E-value: 1.19e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530369823   1 MKKVKKKRSEARRHRDSTSQHASSNSTSQQPSPESTPQ-QPSPESTPQQP------------SPEST-PQHSSLET 62
Cdd:PLN03029 145 MMKTKSKNQKQENQEKQEKLEESEIQSEKQEQPSQQPQsQPQPQQQPQQPnnnkrkameeglSPDRTrPRYNGITT 220
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 18-94 1.70e-03

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 38.53  E-value: 1.70e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530369823  18 TSQHASSNSTSQQP--SPESTPQQPSPESTPQQPSPESTPQHSSLETTSRQPAFqalPAPEIRRSSCCLLSPDANVKAA 94
Cdd:PLN02217 582 TTFSSDSPSTVVAPstSPPAGHLGSPPATPSKIVSPSTSPPASHLGSPSTTPSS---PESSIKVASTETASPESSIKVA 657
DUF4106 pfam13388
Protein of unknown function (DUF4106); This family of proteins are found in large numbers in ...
 9-67 1.80e-03

Protein of unknown function (DUF4106); This family of proteins are found in large numbers in the Trichomonas vaginalis proteome. The function of this protein is unknown.


Pssm-ID: 404296  Cd Length: 431  Bit Score: 38.34  E-value: 1.80e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530369823    9 SEARRHR-------DSTSQHASSNSTSQQPSPESTPQQPSPESTP-QQPSPESTPQHSSLETTSRQP 67
Cdd:pfam13388 192 SHGHRHRhapkptvQNPAQQPTVQNPAQQPTQQPTVQNPAQQQNPaQQPPPQPAQQPTVQNPAQQQP 258
PHA03247 PHA03247
large tegument protein UL36; Provisional
 17-107 4.15e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 37.61  E-value: 4.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823   17 STSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSLETTSRQPafQALPAPEirrsscclLSPDANVKAAPQ 96
Cdd:PHA03247 2885 RLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--PPRPQPP--------LAPTTDPAGAGE 2954

                          90
                  ....*....|.
gi 530369823   97 SRKAGPLIRAG 107
Cdd:PHA03247 2955 PSGAVPQPWLG 2965
PRK12757 PRK12757
cell division protein FtsN; Provisional
 27-78 4.61e-03

cell division protein FtsN; Provisional


Pssm-ID: 237191 [Multi-domain]  Cd Length: 256  Bit Score: 36.56  E-value: 4.61e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 530369823  27 TSQQPSPESTPQQPSPESTPQQPSPESTPQHSSLETTSRQPAFQALPAPEIR 78
Cdd:PRK12757 133 TTAQPQPVTPPRQTTAPVQPQTPAPVRTQPAAPVTQAVEAPKVEAEKEKEQR 184
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
4-109 5.04e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 37.06  E-value: 5.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369823   4 VKKKRSEARRHRDSTSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSLETTSRQPAFQALPAPEIRRSSCC 83
Cdd:PRK14971 369 ASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAVR 448

                         90       100
                 ....*....|....*....|....*..
gi 530369823  84 LLSPDANVKAAP-QSRKAGPLIRAGPH 109
Cdd:PRK14971 449 PAQFKEEKKIPVsKVSSLGPSTLRPIQ 475
DUF4106 pfam13388
Protein of unknown function (DUF4106); This family of proteins are found in large numbers in ...
 6-70 7.92e-03

Protein of unknown function (DUF4106); This family of proteins are found in large numbers in the Trichomonas vaginalis proteome. The function of this protein is unknown.


Pssm-ID: 404296  Cd Length: 431  Bit Score: 36.41  E-value: 7.92e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530369823    6 KKRSEARRHRDSTSQHASSNSTSQQPSPESTPQQPSPESTPQQPSPESTPQHSSLETTSRQPAFQ 70
Cdd:pfam13388 187 KTFTSSHGHRHRHAPKPTVQNPAQQPTVQNPAQQPTQQPTVQNPAQQQNPAQQPPPQPAQQPTVQ 251
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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