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Conserved domains on  [gi|672056299|ref|XP_008762931|]
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ninein isoform X8 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
403-1056 1.77e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.68  E-value: 1.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  403 LERVDQVVREKEK----LRSDLDKAEKLKSLMASEVD-DHHAAIERRNEYNLRKldEEYKERIAALKNELRQEREQI--- 474
Cdd:COG1196   188 LERLEDILGELERqlepLERQAEKAERYRELKEELKElEAELLLLKLRELEAEL--EELEAELEELEAELEELEAELael 265
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  475 ---LQQVGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLENV---LAEKFGD 548
Cdd:COG1196   266 eaeLEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELeeeLEELEEE 345
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  549 LDPSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLpcQNALSEELDGHGDGIEQDQEpgsgec 628
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE--LAAQLEELEEAEEALLERLE------ 417
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  629 nplnmSIEAELVIEQLKEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEIAD 708
Cdd:COG1196   418 -----RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  709 LQGQAAVLKEAHHK-ASCRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEEKAR 787
Cdd:COG1196   493 LLLLLEAEADYEGFlEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  788 SLTRdleqshqeQLLSLMEKHALEKEELRKELSEYHQRELQEGREEMETEcnRRVSQIEAQFQADCEKVTERCEQTLQSL 867
Cdd:COG1196   573 RATF--------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR--YYVLGDTLLGRTLVAARLEAALRRAVTL 642
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  868 EGRYRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKTHKERLAILSMEREQLL 947
Cdd:COG1196   643 AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  948 QDLKDLQNTSERQHSLLSDQMLELKRSQERELREPEhvlcqtGVSEQLGSQQLARLqvehEQERREMaGKI--AALESAh 1025
Cdd:COG1196   723 EEALEEQLEAEREELLEELLEEEELLEEEALEELPE------PPDLEELERELERL----EREIEAL-GPVnlLAIEEY- 790
                         650       660       670
                  ....*....|....*....|....*....|.
gi 672056299 1026 rvscERADQEKAEMSAEIRRLQSTVKDLQQA 1056
Cdd:COG1196   791 ----EELEERYDFLSEQREDLEEARETLEEA 817
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1454-1773 2.57e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 2.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1454 VILEESAALLGLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKqkdapsqgeEEEELKAVMHDLQITCGEMQRK 1533
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK---------ELEELSRQISALRKDLARLEAE 741
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1534 VELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQ 1613
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1614 LDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDPGTCTSEKWEQENESLKE--ELDRYKVQTSTLVSSLEAELSEVKL 1691
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEleALLNERASLEEALALLRSELEELSE 901
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1692 QTHIVEQENLLLKDELERLKQLhrcpdLSDFQQKMCS----ILSYNENLLKEKEVLSEELKSCADKL-AESSLLEHRIAT 1766
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREK-----LAQLELRLEGlevrIDNLQERLSEEYSLTLEEAEALENKIeDDEEEARRRLKR 976

                   ....*..
gi 672056299  1767 IKEEREA 1773
Cdd:TIGR02168  977 LENKIKE 983
CCDC158 super family cl37899
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1045-1982 4.13e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


The actual alignment was detected with superfamily member pfam15921:

Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 4.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1045 RLQSTVKDLQQATSLLVLQGGCRATAGEEAEgngalSLLQQGEQLLEENGDVLISLQKAHERAVKENAKMATEISRlqqr 1124
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLR-----KMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---- 216
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1125 lkklEPGSAISSCLEERMTEISgssrehaepvmkrgtatkhFLSD---PGDHEAQGLGSTGTSSV----QRQECRTEE-- 1195
Cdd:pfam15921  217 ----SLGSAISKILRELDTEIS-------------------YLKGrifPVEDQLEALKSESQNKIelllQQHQDRIEQli 273
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1196 SEASLECFSELENSEDTRTESWDLKSQIIQLQEQLtvlRADCDRASERKRDLLFDISVLKKKLKMLERLpeasskykvlY 1275
Cdd:pfam15921  274 SEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA---RNQNSMYMRQLSDLESTVSQLRSELREAKRM----------Y 340
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1276 EDAAREnacLQEELRLMEMRYADSLDSNKELTAEVYRLQDEMKKM----------------------EEVTGTFLS---L 1330
Cdd:pfam15921  341 EDKIEE---LEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladlhkrekelslekeqnkrlwDRDTGNSITidhL 417
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1331 ENSYDEVKLENEKLSALVLRLQGKMEEVLER--AALQGDSYSLWEGPSENLEVTSDEKMLElhQTEEECTPEVMSRHHii 1408
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLKAMKSECQGQMERqmAAIQGKNESLEKVSSLTAQLESTKEMLR--KVVEELTAKKMTLES-- 493
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1409 eecrqetrcCEQGSTQLLAGIKAHEiawfrRKIE-THQEKPSVQNRVILE-ESAALLGLQGTHLQHEATIAE-LEL---E 1482
Cdd:pfam15921  494 ---------SERTVSDLTASLQEKE-----RAIEaTNAEITKLRSRVDLKlQELQHLKNEGDHLRNVQTECEaLKLqmaE 559
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1483 KQKLQELTRNLRERVTTLAKQ--KDAPSQGEEEEELKAVMHDlqitcgemqRKVELLRYESEKLQEENSILRneittlnE 1560
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQhgRTAGAMQVEKAQLEKEIND---------RRLELQEFKILKDKKDAKIRE-------L 623
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1561 EDSISNLKLEEL---NGSQEELwQKIETIEQEKASIQKMVEKLKKQVSDLklknqqldSENKELSQKNSQNK-EELKTln 1636
Cdd:pfam15921  624 EARVSDLELEKVklvNAGSERL-RAVKDIKQERDQLLNEVKTSRNELNSL--------SEDYEVLKRNFRNKsEEMET-- 692
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1637 qrlaemlcqkedpgtcTSEKWEQENESLKEELDrykvQTSTLVSSLEAElsevklQTHIVEQENLLLKDELERLKQLhrc 1716
Cdd:pfam15921  693 ----------------TTNKLKMQLKSAQSELE----QTRNTLKSMEGS------DGHAMKVAMGMQKQITAKRGQI--- 743
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1717 pdlSDFQQKMCSILSYNENLLKEKEVLSEElkscadklaeSSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLE 1796
Cdd:pfam15921  744 ---DALQSKIQFLEEAMTNANKEKHFLKEE----------KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1797 DILKNVNLQMAQIESDLQvtRQEKEalkqevmSLHLQLQNAIDkdwvsetathLSGLQGQQKRLSWNKLDHLMseEPELL 1876
Cdd:pfam15921  811 VALDKASLQFAECQDIIQ--RQEQE-------SVRLKLQHTLD----------VKELQGPGYTSNSSMKPRLL--QPASF 869
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1877 CQESKRLQTvVQNTQADLTHSREKIRQLESNllPTKHQKQLNQSCTVKPIEQEKLALKRECEQSRKERSPTSRKVSQMSS 1956
Cdd:pfam15921  870 TRTHSNVPS-SQSTASFLSHHSRKTNALKED--PTRDLKQLLQELRSVINEEPTVQLSKAEDKGRAPSLGALDDRVRDCI 946
                          970       980
                   ....*....|....*....|....*...
gi 672056299  1957 LEREL--ETIHLENEGLKKKQVRLDEKL 1982
Cdd:pfam15921  947 IESSLrsDICHSSSNSLQTEGSKSSETC 974
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
403-1056 1.77e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.68  E-value: 1.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  403 LERVDQVVREKEK----LRSDLDKAEKLKSLMASEVD-DHHAAIERRNEYNLRKldEEYKERIAALKNELRQEREQI--- 474
Cdd:COG1196   188 LERLEDILGELERqlepLERQAEKAERYRELKEELKElEAELLLLKLRELEAEL--EELEAELEELEAELEELEAELael 265
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  475 ---LQQVGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLENV---LAEKFGD 548
Cdd:COG1196   266 eaeLEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELeeeLEELEEE 345
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  549 LDPSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLpcQNALSEELDGHGDGIEQDQEpgsgec 628
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE--LAAQLEELEEAEEALLERLE------ 417
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  629 nplnmSIEAELVIEQLKEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEIAD 708
Cdd:COG1196   418 -----RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  709 LQGQAAVLKEAHHK-ASCRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEEKAR 787
Cdd:COG1196   493 LLLLLEAEADYEGFlEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  788 SLTRdleqshqeQLLSLMEKHALEKEELRKELSEYHQRELQEGREEMETEcnRRVSQIEAQFQADCEKVTERCEQTLQSL 867
Cdd:COG1196   573 RATF--------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR--YYVLGDTLLGRTLVAARLEAALRRAVTL 642
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  868 EGRYRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKTHKERLAILSMEREQLL 947
Cdd:COG1196   643 AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  948 QDLKDLQNTSERQHSLLSDQMLELKRSQERELREPEhvlcqtGVSEQLGSQQLARLqvehEQERREMaGKI--AALESAh 1025
Cdd:COG1196   723 EEALEEQLEAEREELLEELLEEEELLEEEALEELPE------PPDLEELERELERL----EREIEAL-GPVnlLAIEEY- 790
                         650       660       670
                  ....*....|....*....|....*....|.
gi 672056299 1026 rvscERADQEKAEMSAEIRRLQSTVKDLQQA 1056
Cdd:COG1196   791 ----EELEERYDFLSEQREDLEEARETLEEA 817
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
388-981 1.20e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.47  E-value: 1.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   388 HQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIER-RNEYN-LRKLDEEYKERIAALKN 465
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEElKEELEsLEAELEELEAELEELES 372
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   466 ELRQEREQILQQVGKqRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRS-LENVLAE 544
Cdd:TIGR02168  373 RLEELEEQLETLRSK-VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEeLEEELEE 451
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   545 KFGDLDPSSAEFFLQEERLAQMRNE---YEQQCRLLQDQVDELQSELEEYQAQGR------------------------- 596
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQAldaAERELAQLQARLDSLERLQENLEGFSEgvkallknqsglsgilgvlselisv 531
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   597 ----------VLRLPCQNALSEELDGHGDGIEQDQEPGSGECNPLNMSIEAELVIEQLKE---QHHRDLCHLRLELEDKV 663
Cdd:TIGR02168  532 degyeaaieaALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDReilKNIEGFLGVAKDLVKFD 611
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   664 RHYEKQ----LDHTRVACEKEQ-VAMKQKYEQGMR----------------------------------TLEKQISELQS 704
Cdd:TIGR02168  612 PKLRKAlsylLGGVLVVDDLDNaLELAKKLRPGYRivtldgdlvrpggvitggsaktnssilerrreieELEEKIEELEE 691
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   705 EIADLQGQAAVLKEAH--------------HKASCRHEEEKKQLQMvfdEEKTQLQEELRLEHEQELKARLQQAEESFRQ 770
Cdd:TIGR02168  692 KIAELEKALAELRKELeeleeeleqlrkelEELSRQISALRKDLAR---LEAEVEQLEERIAQLSKELTELEAEIEELEE 768
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   771 EREGLAQAAAWTEEKARSLTRDLEQsHQEQLLSLMEKHalekEELRKELSEyHQRELQEGREEMEtECNRRVSQIEAQFQ 850
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQ-LKEELKALREAL----DELRAELTL-LNEEAANLRERLE-SLERRIAATERRLE 841
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   851 aDCEKVTERCEQTLQSLEGRYRQ------ELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKAtALARSQE 924
Cdd:TIGR02168  842 -DLEEQIEELSEDIESLAAEIEEleelieELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE-LRRELEE 919
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 672056299   925 QETLEKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQERELRE 981
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1454-1773 2.57e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 2.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1454 VILEESAALLGLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKqkdapsqgeEEEELKAVMHDLQITCGEMQRK 1533
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK---------ELEELSRQISALRKDLARLEAE 741
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1534 VELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQ 1613
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1614 LDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDPGTCTSEKWEQENESLKE--ELDRYKVQTSTLVSSLEAELSEVKL 1691
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEleALLNERASLEEALALLRSELEELSE 901
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1692 QTHIVEQENLLLKDELERLKQLhrcpdLSDFQQKMCS----ILSYNENLLKEKEVLSEELKSCADKL-AESSLLEHRIAT 1766
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREK-----LAQLELRLEGlevrIDNLQERLSEEYSLTLEEAEALENKIeDDEEEARRRLKR 976

                   ....*..
gi 672056299  1767 IKEEREA 1773
Cdd:TIGR02168  977 LENKIKE 983
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1045-1982 4.13e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 4.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1045 RLQSTVKDLQQATSLLVLQGGCRATAGEEAEgngalSLLQQGEQLLEENGDVLISLQKAHERAVKENAKMATEISRlqqr 1124
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLR-----KMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---- 216
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1125 lkklEPGSAISSCLEERMTEISgssrehaepvmkrgtatkhFLSD---PGDHEAQGLGSTGTSSV----QRQECRTEE-- 1195
Cdd:pfam15921  217 ----SLGSAISKILRELDTEIS-------------------YLKGrifPVEDQLEALKSESQNKIelllQQHQDRIEQli 273
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1196 SEASLECFSELENSEDTRTESWDLKSQIIQLQEQLtvlRADCDRASERKRDLLFDISVLKKKLKMLERLpeasskykvlY 1275
Cdd:pfam15921  274 SEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA---RNQNSMYMRQLSDLESTVSQLRSELREAKRM----------Y 340
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1276 EDAAREnacLQEELRLMEMRYADSLDSNKELTAEVYRLQDEMKKM----------------------EEVTGTFLS---L 1330
Cdd:pfam15921  341 EDKIEE---LEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladlhkrekelslekeqnkrlwDRDTGNSITidhL 417
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1331 ENSYDEVKLENEKLSALVLRLQGKMEEVLER--AALQGDSYSLWEGPSENLEVTSDEKMLElhQTEEECTPEVMSRHHii 1408
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLKAMKSECQGQMERqmAAIQGKNESLEKVSSLTAQLESTKEMLR--KVVEELTAKKMTLES-- 493
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1409 eecrqetrcCEQGSTQLLAGIKAHEiawfrRKIE-THQEKPSVQNRVILE-ESAALLGLQGTHLQHEATIAE-LEL---E 1482
Cdd:pfam15921  494 ---------SERTVSDLTASLQEKE-----RAIEaTNAEITKLRSRVDLKlQELQHLKNEGDHLRNVQTECEaLKLqmaE 559
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1483 KQKLQELTRNLRERVTTLAKQ--KDAPSQGEEEEELKAVMHDlqitcgemqRKVELLRYESEKLQEENSILRneittlnE 1560
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQhgRTAGAMQVEKAQLEKEIND---------RRLELQEFKILKDKKDAKIRE-------L 623
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1561 EDSISNLKLEEL---NGSQEELwQKIETIEQEKASIQKMVEKLKKQVSDLklknqqldSENKELSQKNSQNK-EELKTln 1636
Cdd:pfam15921  624 EARVSDLELEKVklvNAGSERL-RAVKDIKQERDQLLNEVKTSRNELNSL--------SEDYEVLKRNFRNKsEEMET-- 692
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1637 qrlaemlcqkedpgtcTSEKWEQENESLKEELDrykvQTSTLVSSLEAElsevklQTHIVEQENLLLKDELERLKQLhrc 1716
Cdd:pfam15921  693 ----------------TTNKLKMQLKSAQSELE----QTRNTLKSMEGS------DGHAMKVAMGMQKQITAKRGQI--- 743
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1717 pdlSDFQQKMCSILSYNENLLKEKEVLSEElkscadklaeSSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLE 1796
Cdd:pfam15921  744 ---DALQSKIQFLEEAMTNANKEKHFLKEE----------KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1797 DILKNVNLQMAQIESDLQvtRQEKEalkqevmSLHLQLQNAIDkdwvsetathLSGLQGQQKRLSWNKLDHLMseEPELL 1876
Cdd:pfam15921  811 VALDKASLQFAECQDIIQ--RQEQE-------SVRLKLQHTLD----------VKELQGPGYTSNSSMKPRLL--QPASF 869
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1877 CQESKRLQTvVQNTQADLTHSREKIRQLESNllPTKHQKQLNQSCTVKPIEQEKLALKRECEQSRKERSPTSRKVSQMSS 1956
Cdd:pfam15921  870 TRTHSNVPS-SQSTASFLSHHSRKTNALKED--PTRDLKQLLQELRSVINEEPTVQLSKAEDKGRAPSLGALDDRVRDCI 946
                          970       980
                   ....*....|....*....|....*...
gi 672056299  1957 LEREL--ETIHLENEGLKKKQVRLDEKL 1982
Cdd:pfam15921  947 IESSLrsDICHSSSNSLQTEGSKSSETC 974
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1477-1801 4.59e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 4.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1477 AELELEK-----QKLQELTRNLRERVTTLAKQKDAPSQ----GEEEEELKAV-----MHDLQITCGEMQRKVELLRYESE 1542
Cdd:COG1196   177 AERKLEAteenlERLEDILGELERQLEPLERQAEKAERyrelKEELKELEAEllllkLRELEAELEELEAELEELEAELE 256
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1543 KLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELS 1622
Cdd:COG1196   257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1623 QKNSQNKEELKTLNQRLAEMLCQKEDpgtcTSEKWEQENESLKEELDRYKVQTSTLVSSLEAELSEVKLQTHIVEQENLL 1702
Cdd:COG1196   337 EELEELEEELEEAEEELEEAEAELAE----AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1703 LKDELERLKQLHRCPDlsdfqqkmcSILSYNENLLKEKEVLSEELKSCADKLAESSLLEHRIATIKEEREAWEEQSQDLK 1782
Cdd:COG1196   413 LERLERLEEELEELEE---------ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483
                         330
                  ....*....|....*....
gi 672056299 1783 SQLALSQEKVQNLEDILKN 1801
Cdd:COG1196   484 EELAEAAARLLLLLEAEAD 502
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
657-1600 2.07e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.15  E-value: 2.07e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   657 LELEDKVRHYEKQLdhtrvacekeQVAMKQKYEQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQM 736
Cdd:TIGR02168  216 KELKAELRELELAL----------LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE 285
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   737 VFDEEKTQLQEELRLEHE-QELKARLQQAEESFRQEREGLAQAAAWTEEKARSLTRdleqsHQEQLLSLMEKHALEKEEL 815
Cdd:TIGR02168  286 LQKELYALANEISRLEQQkQILRERLANLERQLEELEAQLEELESKLDELAEELAE-----LEEKLEELKEELESLEAEL 360
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   816 RKELSEYHQRE--LQEGREEMETEcNRRVSQIEAQfQADCEKVTERCEQTLQSLEGRyRQELKDLLDQHLEERSqwEFEK 893
Cdd:TIGR02168  361 EELEAELEELEsrLEELEEQLETL-RSKVAQLELQ-IASLNNEIERLEARLERLEDR-RERLQQEIEELLKKLE--EAEL 435
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   894 DELTQECTEAQEQLEEVLQREKAtalarsqeqetlektHKERLAILSMEREQLLQDLKDLqntsERQHSLLSDQMLELKR 973
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELER---------------LEEALEELREELEEAEQALDAA----ERELAQLQARLDSLER 496
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   974 SQERELREPEHVLCQTGVSEQLGSQQLARLQVEHEQERREMAGKIAALESAHRVSCERADQEKaemsaeirrlqstvkdl 1053
Cdd:TIGR02168  497 LQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAK----------------- 559
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1054 qQATSLLVLQGGCRATAGEEAEGNGALSLLQQGEQLLEENG--DVLISLQKAHERAVK------ENAKMATEISRLQQRL 1125
Cdd:TIGR02168  560 -KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGflGVAKDLVKFDPKLRKalsyllGGVLVVDDLDNALELA 638
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1126 KKLEPGSAISScleermteisgssrEHAEPVMKRGTATKhflsdpgdheaqglGSTGTSSVqRQECRTEESEASlECFSE 1205
Cdd:TIGR02168  639 KKLRPGYRIVT--------------LDGDLVRPGGVITG--------------GSAKTNSS-ILERRREIEELE-EKIEE 688
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1206 LENSEDtrteswDLKSQIIQLQEQLTVLRADCDRASERKRDLLFDISVLKKKLKMLERLPEASSKykvLYEDAARENACL 1285
Cdd:TIGR02168  689 LEEKIA------ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE---RIAQLSKELTEL 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1286 QEELRLMEMRYADSLDSNKELTAEVYRLQDEMKKMEEvtgTFLSLENSYDEVKLENEKLSALVLRLQGKMEEVLERAALQ 1365
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE---ELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1366 GDSyslwegpsenlevtsdekMLELHQTEEECTPEVMSRHHIIEECRQetrcceqgstqllagikahEIAWFRRKIETHQ 1445
Cdd:TIGR02168  837 ERR------------------LEDLEEQIEELSEDIESLAAEIEELEE-------------------LIEELESELEALL 879
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1446 EKPSVQNRVILEESAALLGLqgthlqhEATIAELELEKQKLQELTRNLRERVTTLAKQKDApSQGEEEEELKAVMHDLQI 1525
Cdd:TIGR02168  880 NERASLEEALALLRSELEEL-------SEELRELESKRSELRRELEELREKLAQLELRLEG-LEVRIDNLQERLSEEYSL 951
                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672056299  1526 TCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKL 1600
Cdd:TIGR02168  952 TLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
433-1232 4.56e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 4.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   433 EVDDHHAAIERRNEYNLRKLDEEYKERIAALK------NELRQEREQILQQVGKQRVELEQEIEKAKTEENYIRDRLALS 506
Cdd:pfam15921   60 ELDSPRKIIAYPGKEHIERVLEEYSHQVKDLQrrlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQS 139
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   507 LKE-NNRLENEL--LENAEKLAE--YENLTSKLQR------SLENVLAEKFG---DLDPSSAEFFLQEERLAQMR----- 567
Cdd:pfam15921  140 QEDlRNQLQNTVheLEAAKCLKEdmLEDSNTQIEQlrkmmlSHEGVLQEIRSilvDFEEASGKKIYEHDSMSTMHfrslg 219
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   568 NEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNALSEELDGHGDGIEQ------------DQEPGSGECNPLNMSI 635
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQliseheveitglTEKASSARSQANSIQS 299
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   636 EAELVIEQLKEQHHRDLCHLRlELEDKVRHYEKQLDHTrvacekeqvamKQKYEQGMRTLEKQISELQSEIADlqgqaav 715
Cdd:pfam15921  300 QLEIIQEQARNQNSMYMRQLS-DLESTVSQLRSELREA-----------KRMYEDKIEELEKQLVLANSELTE------- 360
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   716 lkeahhkasCRHEEEKkqlqmvFDEEKTQLQEELrleheQELKARLQQAEESFRQEREglAQAAAWTEEKARSLTRD-LE 794
Cdd:pfam15921  361 ---------ARTERDQ------FSQESGNLDDQL-----QKLLADLHKREKELSLEKE--QNKRLWDRDTGNSITIDhLR 418
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   795 QSHQEQLLSLMEKHALEKeELRKELSeyHQRELQEGREEMETECNRRVSQIEAQFQADCE---KVTERCEQTLQSLEGRY 871
Cdd:pfam15921  419 RELDDRNMEVQRLEALLK-AMKSECQ--GQMERQMAAIQGKNESLEKVSSLTAQLESTKEmlrKVVEELTAKKMTLESSE 495
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   872 RQeLKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEV--LQREKATALARSQEQETLEKTHKERLAILSMEREQlLQD 949
Cdd:pfam15921  496 RT-VSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELqhLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQ-IEN 573
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   950 LKDLQNtserQHSLLSDQMLELKRSQERELREpehvlcqtgvsEQLGSQQLARLQVEHEQERREMAGKIAALE------- 1022
Cdd:pfam15921  574 MTQLVG----QHGRTAGAMQVEKAQLEKEIND-----------RRLELQEFKILKDKKDAKIRELEARVSDLElekvklv 638
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1023 ---SAHRVSCERADQEKAEMSAEIRRLQSTVKDLQQATSllVLQGGCRATAGE-EAEGNGALSLLQQGEQLLEENGDVLI 1098
Cdd:pfam15921  639 nagSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE--VLKRNFRNKSEEmETTTNKLKMQLKSAQSELEQTRNTLK 716
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1099 SLQKAHERAVKENAKMATEISRLQQRLKKLEpgsaisscleermteisgSSREHAEPVMKRGTATKHFLSDPGDHEAQGL 1178
Cdd:pfam15921  717 SMEGSDGHAMKVAMGMQKQITAKRGQIDALQ------------------SKIQFLEEAMTNANKEKHFLKEEKNKLSQEL 778
                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672056299  1179 GSTGTSS---------VQRQECRTEESEASLECfsELENSEDTRTESWDlksqIIQLQEQLTV 1232
Cdd:pfam15921  779 STVATEKnkmagelevLRSQERRLKEKVANMEV--ALDKASLQFAECQD----IIQRQEQESV 835
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
398-611 1.75e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 53.01  E-value: 1.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  398 EIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALkNELRQEREQILQQ 477
Cdd:PRK05771   44 RLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEI-SELENEIKELEQE 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  478 vgKQRVE----LEQEIEKAKTEENYIrdRLALSLKENNRLENELLENAEKLAEYENLTSKL------QRSLENVLAEKFG 547
Cdd:PRK05771  123 --IERLEpwgnFDLDLSLLLGFKYVS--VFVGTVPEDKLEELKLESDVENVEYISTDKGYVyvvvvvLKELSDEVEEELK 198
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672056299  548 DLDPSSAEFFlQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNALSEELD 611
Cdd:PRK05771  199 KLGFERLELE-EEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELE 261
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
1532-1811 3.28e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 52.24  E-value: 3.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1532 RKVELL---RYES---EKLQEENSIlrnEITTLNEEdsISNLKLEELNGSQEELWQKIETIEQ-------EKASIQKM-V 1597
Cdd:PRK05771    7 KKVLIVtlkSYKDevlEALHELGVV---HIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSylpklnpLREEKKKVsV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1598 EKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQK---EDP-------------GTCTSEKWE--- 1658
Cdd:PRK05771   82 KSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGnfdLDLslllgfkyvsvfvGTVPEDKLEelk 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1659 QENESLKEELDRYKVQTSTLVSSLEAELSEvklqthivEQENLLLKDELERLKqlhrCPDLSDFQQKMCSILSYNENLLK 1738
Cdd:PRK05771  162 LESDVENVEYISTDKGYVYVVVVVLKELSD--------EVEEELKKLGFERLE----LEEEGTPSELIREIKEELEEIEK 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1739 EKEVLSEELKSCADKLAEssllehRIATIKEEREAwEEQSQDLKSQLALSQ-----------EKVQNLEDILKNVNLQMA 1807
Cdd:PRK05771  230 ERESLLEELKELAKKYLE------ELLALYEYLEI-ELERAEALSKFLKTDktfaiegwvpeDRVKKLKELIDKATGGSA 302

                  ....
gi 672056299 1808 QIES 1811
Cdd:PRK05771  303 YVEF 306
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1760-1982 4.55e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 4.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1760 LEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQLQNAID 1839
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1840 KDWVSETATHLSGLqgqqkrlswnkldhLMSEEPELLCQESKRLQTVVQNTQADLTHSREKIRQLEsnllpTKHQKQLNQ 1919
Cdd:COG4942   112 ALYRLGRQPPLALL--------------LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA-----ALRAELEAE 172
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672056299 1920 SCTVKPIEQEKLALKRECEQSRKERSptsrkvSQMSSLERELETIHLENEGLKKKQVRLDEKL 1982
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQ------KLLARLEKELAELAAELAELQQEAEELEALI 229
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
1444-1974 5.14e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.56  E-value: 5.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1444 HQEKPSVQNRVILEesAALLGLQGTHLQHEATIAELELEKQKLQELTR--NLRERVTTLAKQKDAPSQGE------EEEE 1515
Cdd:pfam05483  103 QKENKLQENRKIIE--AQRKAIQELQFENEKVSLKLEEEIQENKDLIKenNATRHLCNLLKETCARSAEKtkkyeyEREE 180
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1516 LKAVMHDLQITCGEMqrkveLLRYESEKLQEENSILRNEITTLNEEDSISNLKLE---ELNGSQEE---LWQKIETIEQE 1589
Cdd:pfam05483  181 TRQVYMDLNNNIEKM-----ILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEykkEINDKEKQvslLLIQITEKENK 255
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1590 KASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKE------DPGTCTSEKWEQENES 1663
Cdd:pfam05483  256 MKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKaleedlQIATKTICQLTEEKEA 335
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1664 LKEELDRYKVQTSTLVSSLEAELSEVKLqthiveqenlLLKDELERLKQLHRCPDLSDFQ-QKMCSILSYNENLLKEKEV 1742
Cdd:pfam05483  336 QMEELNKAKAAHSFVVTEFEATTCSLEE----------LLRTEQQRLEKNEDQLKIITMElQKKSSELEEMTKFKNNKEV 405
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1743 LSEELKSCadkLAESSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQ--VTRQEK 1820
Cdd:pfam05483  406 ELEELKKI---LAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEdlKTELEK 482
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1821 EALKQEVMSLHLQLQNAIDKDWVSETATHLSGLQGQQKRLSWNKldhlmsEEPELLCQESKRLQTVVQNTQADLTHSREK 1900
Cdd:pfam05483  483 EKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCK------KQEERMLKQIENLEEKEMNLRDELESVREE 556
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672056299  1901 IRQLESNL---LPTKHQKQLNQSCTVKPIEQEKLALKRECEQSRKersptsrkvsQMSSLERELETIHLENEGLKKK 1974
Cdd:pfam05483  557 FIQKGDEVkckLDKSEENARSIEYEVLKKEKQMKILENKCNNLKK----------QIENKNKNIEELHQENKALKKK 623
PTZ00121 PTZ00121
MAEBL; Provisional
884-1710 2.49e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 2.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  884 EERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKTHKERlailsmeREQLLQDLKDLQNTSERQHSL 963
Cdd:PTZ00121 1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAK-------RVEIARKAEDARKAEEARKAE 1173
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  964 LSDQMLELKRSQEreLREPEHVLCQTGVSEQLGSQQLARLQVEHEQERREMAGKIAALESAHRVsceRADQEKAEMSAEI 1043
Cdd:PTZ00121 1174 DAKKAEAARKAEE--VRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEA---KKDAEEAKKAEEE 1248
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1044 RRLQSTVKDLQQATSLLVlqggcRATAGEEAEGNGALSLLQQGEQLLEENgdvliSLQKAHE-RAVKENAKMATEISRLQ 1122
Cdd:PTZ00121 1249 RNNEEIRKFEEARMAHFA-----RRQAAIKAEEARKADELKKAEEKKKAD-----EAKKAEEkKKADEAKKKAEEAKKAD 1318
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1123 QRLKKLEPGSAISSCLEERMTEisgsSREHAEPVMKRGTATKHflsdpgdhEAQGLGSTGTSSVQRQECRTEESEASLEC 1202
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEE----AKKAAEAAKAEAEAAAD--------EAEAAEEKAEAAEKKKEEAKKKADAAKKK 1386
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1203 FSELENSEDTRTESWDLKSQIIQLQ----EQLTVLRADCDRASERKRDLLFDISVLKKKLKMLERLPEASSKYKVLYEDA 1278
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEEDKKKADELKkaaaAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKA 1466
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1279 ARENACLQEELRLMEMRYADSLDSNKEltaEVYRLQDEMKKMEEVTGTFLSLENS-----YDEVKLENEKLSALVLRlqg 1353
Cdd:PTZ00121 1467 EEAKKADEAKKKAEEAKKADEAKKKAE---EAKKKADEAKKAAEAKKKADEAKKAeeakkADEAKKAEEAKKADEAK--- 1540
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1354 KMEEVLERAALQgdsyslwegPSENLEVTSDEKMLELHQTEEECTPEVMSRHHI---IEECRQETRC----------CEQ 1420
Cdd:PTZ00121 1541 KAEEKKKADELK---------KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakkAEEARIEEVMklyeeekkmkAEE 1611
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1421 GSTQLLAGIKAHEIawfrRKIETHQEKPSVQNRVILEESAALLGLQGthlQHEATIAELELEKQKLQELTRNLRERVTTL 1500
Cdd:PTZ00121 1612 AKKAEEAKIKAEEL----KKAEEEKKKVEQLKKKEAEEKKKAEELKK---AEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1501 AKQKDAPSQGEEEEELKAVMHDLQITCGEMQRKVELLRyeseKLQEENSILRNEITTLNEEDsisNLKLEELNGSQEELw 1580
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELK----KAEEENKIKAEEAKKEAEED---KKKAEEAKKDEEEK- 1756
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1581 QKIETIEQEKASIQKMVEKLKKQV--SDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEML-CQKEDPGTCTSEKW 1657
Cdd:PTZ00121 1757 KKIAHLKKEEEKKAEEIRKEKEAVieEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVInDSKEMEDSAIKEVA 1836
                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 672056299 1658 EQENESLKE--ELDRYKVQTSTLVSSLEAELSEVKLQTHIVE--QENLLLKDELERL 1710
Cdd:PTZ00121 1837 DSKNMQLEEadAFEKHKFNKNNENGEDGNKEADFNKEKDLKEddEEEIEEADEIEKI 1893
GBP_C cd16269
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...
739-851 5.12e-03

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.


Pssm-ID: 293879 [Multi-domain]  Cd Length: 291  Bit Score: 41.02  E-value: 5.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  739 DEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEEKarslTRDLEQSHQEQLLSLMEKHALEKEELRKE 818
Cdd:cd16269   181 AEAEAILQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQRELEQK----LEDQERSYEEHLRQLKEKMEEERENLLKE 256
                          90       100       110
                  ....*....|....*....|....*....|...
gi 672056299  819 LSEYHQRELQEGREEMETECNRRVSQIEAQFQA 851
Cdd:cd16269   257 QERALESKLKEQEALLEEGFKEQAELLQEEIRS 289
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
403-1056 1.77e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.68  E-value: 1.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  403 LERVDQVVREKEK----LRSDLDKAEKLKSLMASEVD-DHHAAIERRNEYNLRKldEEYKERIAALKNELRQEREQI--- 474
Cdd:COG1196   188 LERLEDILGELERqlepLERQAEKAERYRELKEELKElEAELLLLKLRELEAEL--EELEAELEELEAELEELEAELael 265
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  475 ---LQQVGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLENV---LAEKFGD 548
Cdd:COG1196   266 eaeLEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELeeeLEELEEE 345
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  549 LDPSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLpcQNALSEELDGHGDGIEQDQEpgsgec 628
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE--LAAQLEELEEAEEALLERLE------ 417
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  629 nplnmSIEAELVIEQLKEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEIAD 708
Cdd:COG1196   418 -----RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  709 LQGQAAVLKEAHHK-ASCRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEEKAR 787
Cdd:COG1196   493 LLLLLEAEADYEGFlEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  788 SLTRdleqshqeQLLSLMEKHALEKEELRKELSEYHQRELQEGREEMETEcnRRVSQIEAQFQADCEKVTERCEQTLQSL 867
Cdd:COG1196   573 RATF--------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR--YYVLGDTLLGRTLVAARLEAALRRAVTL 642
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  868 EGRYRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKTHKERLAILSMEREQLL 947
Cdd:COG1196   643 AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  948 QDLKDLQNTSERQHSLLSDQMLELKRSQERELREPEhvlcqtGVSEQLGSQQLARLqvehEQERREMaGKI--AALESAh 1025
Cdd:COG1196   723 EEALEEQLEAEREELLEELLEEEELLEEEALEELPE------PPDLEELERELERL----EREIEAL-GPVnlLAIEEY- 790
                         650       660       670
                  ....*....|....*....|....*....|.
gi 672056299 1026 rvscERADQEKAEMSAEIRRLQSTVKDLQQA 1056
Cdd:COG1196   791 ----EELEERYDFLSEQREDLEEARETLEEA 817
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
455-1130 2.66e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 2.66e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  455 EYKERIAALKNELRQEREQ------ILQQVGKQRVELEQEIEKAKTeenyirdrlALSLKEnnrlENELLENAEKLAEYE 528
Cdd:COG1196   169 KYKERKEEAERKLEATEENlerledILGELERQLEPLERQAEKAER---------YRELKE----ELKELEAELLLLKLR 235
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  529 NLTSKLQRSLENVLAEKfgdldpssaeffLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQgrvlrlpcQNALSE 608
Cdd:COG1196   236 ELEAELEELEAELEELE------------AELEELEAELAELEAELEELRLELEELELELEEAQAE--------EYELLA 295
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  609 ELDGHGDGIEQDQEpgsgecnplnMSIEAELVIEQLKEQhhrdlchlRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKy 688
Cdd:COG1196   296 ELARLEQDIARLEE----------RRRELEERLEELEEE--------LAELEEELEELEEELEELEEELEEAEEELEEA- 356
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  689 EQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEESF 768
Cdd:COG1196   357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  769 RQEREGLAQAAAWTEEKARSLTRDLEQSHQEQLLSLMEKHALEKEELRKELSEYHQRELQegrEEMETECNRRVSQIEAQ 848
Cdd:COG1196   437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL---LEAEADYEGFLEGVKAA 513
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  849 FQADCEKVTERCEQTLQSLEGRYRQELKDLLDQHLEERsqwefekdeLTQECTEAQEQLEEVLQR--EKATALARSQEQE 926
Cdd:COG1196   514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI---------VVEDDEVAAAAIEYLKAAkaGRATFLPLDKIRA 584
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  927 TLEKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQERELREPEHVlcQTGVSEQLGSQQLARLQVE 1006
Cdd:COG1196   585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLA--GRLREVTLEGEGGSAGGSL 662
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1007 HEQERREMAGKIAALESAHRVSCERADQEKAEMSAEIRRLQSTVKDLQQATSLLVlqggcRATAGEEAEGNGALSLLQQG 1086
Cdd:COG1196   663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL-----EEELEEEALEEQLEAEREEL 737
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....
gi 672056299 1087 EQLLEENGDVLISLQKAHERAVKENAKMATEISRLQQRLKKLEP 1130
Cdd:COG1196   738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
686-1263 5.92e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 5.92e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  686 QKYEQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQmvfdeektQLQEELRLEHEQelKARLQQAE 765
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE--------EAQAEEYELLAE--LARLEQDI 304
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  766 ESFRQEREGLAQAAAWTEEKARSLTRDLEQSHQEQLLSLMEKHALEKEELRKELSEYHQRELQEGREEMETECNRRVSQI 845
Cdd:COG1196   305 ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  846 EAQfQADCEKVTERCEQTLQSLEGRyRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQ 925
Cdd:COG1196   385 AEE-LLEALRAAAELAAQLEELEEA-EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  926 ETLEKTHKERLailsmEREQLLQDLKDLQNTSERQHSLLSdQMLELKRSQERELREPEHVLCQTGVSEQLGsqqlARLQV 1005
Cdd:COG1196   463 ELLAELLEEAA-----LLEAALAELLEELAEAAARLLLLL-EAEADYEGFLEGVKAALLLAGLRGLAGAVA----VLIGV 532
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1006 EHEQERremAGKIAALESAHRVSCERADQEKAEMSAEIRRLQSTVKDLQQATSLLVLQGGCRATAGEEAEG-NGALSLLQ 1084
Cdd:COG1196   533 EAAYEA---ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAvDLVASDLR 609
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1085 QGEQLLEENGDVLISLQKAHERAVKENAKMATEISRLQQRLKKLEPGSAISSCLEERMTEISGSSREHAEpvmkrgtatk 1164
Cdd:COG1196   610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA---------- 679
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1165 hFLSDPGDHEAQGLGSTGTSSVQRQECRTEESEASLECFSELENSEDTRTESWDLKSQIIQLQEQLTVLRADcdrASERK 1244
Cdd:COG1196   680 -ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE---EALEE 755
                         570
                  ....*....|....*....
gi 672056299 1245 RDLLFDISVLKKKLKMLER 1263
Cdd:COG1196   756 LPEPPDLEELERELERLER 774
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
374-956 7.44e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 7.44e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  374 LALENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRN--EYNLRK 451
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQaeEYELLA 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  452 LDEEYKERIAALKnELRQEREQILQQVGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLT 531
Cdd:COG1196   296 ELARLEQDIARLE-ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  532 SKLQRSLENVLAEKFGDLDpssaefflQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNALSEELD 611
Cdd:COG1196   375 AEAEEELEELAEELLEALR--------AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  612 GHGDGIEQDQEpgsgecnpLNMSIEAELVIEQLKEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQG 691
Cdd:COG1196   447 AAEEEAELEEE--------EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  692 MRTLEKQISELQS-EIADLQGQAAVLKEAHHKASCRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEESFRQ 770
Cdd:COG1196   519 LRGLAGAVAVLIGvEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  771 E-REGLAQAAAWTEEKAR-----SLTRDLEQSHQEQLLSLMEKHALEKEELRKEL-------SEYHQRELQEGREEMETE 837
Cdd:COG1196   599 AaVDLVASDLREADARYYvlgdtLLGRTLVAARLEAALRRAVTLAGRLREVTLEGeggsaggSLTGGSRRELLAALLEAE 678
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  838 CNRRVSQIEAQFQADCEKVTERCEQTLQSLEGRYRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKAT 917
Cdd:COG1196   679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPE 758
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 672056299  918 ALARSQEQETLEKTH--------------------KERLAILSMEREQLLQDLKDLQNT 956
Cdd:COG1196   759 PPDLEELERELERLEreiealgpvnllaieeyeelEERYDFLSEQREDLEEARETLEEA 817
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
388-981 1.20e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.47  E-value: 1.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   388 HQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIER-RNEYN-LRKLDEEYKERIAALKN 465
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEElKEELEsLEAELEELEAELEELES 372
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   466 ELRQEREQILQQVGKqRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRS-LENVLAE 544
Cdd:TIGR02168  373 RLEELEEQLETLRSK-VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEeLEEELEE 451
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   545 KFGDLDPSSAEFFLQEERLAQMRNE---YEQQCRLLQDQVDELQSELEEYQAQGR------------------------- 596
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQAldaAERELAQLQARLDSLERLQENLEGFSEgvkallknqsglsgilgvlselisv 531
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   597 ----------VLRLPCQNALSEELDGHGDGIEQDQEPGSGECNPLNMSIEAELVIEQLKE---QHHRDLCHLRLELEDKV 663
Cdd:TIGR02168  532 degyeaaieaALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDReilKNIEGFLGVAKDLVKFD 611
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   664 RHYEKQ----LDHTRVACEKEQ-VAMKQKYEQGMR----------------------------------TLEKQISELQS 704
Cdd:TIGR02168  612 PKLRKAlsylLGGVLVVDDLDNaLELAKKLRPGYRivtldgdlvrpggvitggsaktnssilerrreieELEEKIEELEE 691
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   705 EIADLQGQAAVLKEAH--------------HKASCRHEEEKKQLQMvfdEEKTQLQEELRLEHEQELKARLQQAEESFRQ 770
Cdd:TIGR02168  692 KIAELEKALAELRKELeeleeeleqlrkelEELSRQISALRKDLAR---LEAEVEQLEERIAQLSKELTELEAEIEELEE 768
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   771 EREGLAQAAAWTEEKARSLTRDLEQsHQEQLLSLMEKHalekEELRKELSEyHQRELQEGREEMEtECNRRVSQIEAQFQ 850
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQ-LKEELKALREAL----DELRAELTL-LNEEAANLRERLE-SLERRIAATERRLE 841
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   851 aDCEKVTERCEQTLQSLEGRYRQ------ELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKAtALARSQE 924
Cdd:TIGR02168  842 -DLEEQIEELSEDIESLAAEIEEleelieELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE-LRRELEE 919
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 672056299   925 QETLEKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQERELRE 981
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
384-1130 3.22e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 3.22e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   384 KNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAI-ERRNEYN-LRKLDEEYKERIA 461
Cdd:TIGR02168  219 KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVsELEEEIEeLQKELYALANEIS 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   462 ALKNELRQEREQiLQQVGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYEnltsKLQRSLENV 541
Cdd:TIGR02168  299 RLEQQKQILRER-LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE----AELEELESR 373
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   542 LAEKFGDLDPSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNALSEELDGHGDGIEQDQ 621
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQ 453
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   622 EpgsgecnplnmsiEAELVIEQLKEQHHRdlchlRLELEDKVRHYEKQLDH--TRVACEKEQVAMKQKYEQGMRTLEKQi 699
Cdd:TIGR02168  454 E-------------ELERLEEALEELREE-----LEEAEQALDAAERELAQlqARLDSLERLQENLEGFSEGVKALLKN- 514
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   700 selQSEIADLQGQ---------------AAVLKEAHHKASCRHEEEKKQLqmVFDEEKTQLQEELRLEHEQELKARLQQA 764
Cdd:TIGR02168  515 ---QSGLSGILGVlselisvdegyeaaiEAALGGRLQAVVVENLNAAKKA--IAFLKQNELGRVTFLPLDSIKGTEIQGN 589
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   765 EESFRQEREGLAQAAAWTEEKARSLTRDLE------------QSHQEQLLSLMEKHA---LEKEELRKELSEYHQRELQE 829
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddlDNALELAKKLRPGYRivtLDGDLVRPGGVITGGSAKTN 669
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   830 G-----REEMEtECNRRVSQIEAQFqADCEKVTERCEQTLQSLEgryrQELKDLLDQHLEERSQWEFEKDELTQECTEAQ 904
Cdd:TIGR02168  670 SsilerRREIE-ELEEKIEELEEKI-AELEKALAELRKELEELE----EELEQLRKELEELSRQISALRKDLARLEAEVE 743
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   905 EQLEEVLQREKATALARSQEQETLEKTHKERLAILSMER-----EQLLQDLKDLQNTSERQHSLLSDQMLELKRS----- 974
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAeieelEAQIEQLKEELKALREALDELRAELTLLNEEaanlr 823
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   975 QERELREPEHVLCQ---TGVSEQLG--SQQLARLQVEHEQERREMAGKIAALESA------HRVSCERADQEKAEMSAEI 1043
Cdd:TIGR02168  824 ERLESLERRIAATErrlEDLEEQIEelSEDIESLAAEIEELEELIEELESELEALlnerasLEEALALLRSELEELSEEL 903
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1044 RRLQSTVKDLQQATSLLVLQGGCRATAGEEAEGNgalsLLQQGEQLLEENGDVLISLQKAHERAVKENAKMATEISRLQQ 1123
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVR----IDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979

                   ....*..
gi 672056299  1124 RLKKLEP 1130
Cdd:TIGR02168  980 KIKELGP 986
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1454-1773 2.57e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 2.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1454 VILEESAALLGLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKqkdapsqgeEEEELKAVMHDLQITCGEMQRK 1533
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK---------ELEELSRQISALRKDLARLEAE 741
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1534 VELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQ 1613
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1614 LDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDPGTCTSEKWEQENESLKE--ELDRYKVQTSTLVSSLEAELSEVKL 1691
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEleALLNERASLEEALALLRSELEELSE 901
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1692 QTHIVEQENLLLKDELERLKQLhrcpdLSDFQQKMCS----ILSYNENLLKEKEVLSEELKSCADKL-AESSLLEHRIAT 1766
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREK-----LAQLELRLEGlevrIDNLQERLSEEYSLTLEEAEALENKIeDDEEEARRRLKR 976

                   ....*..
gi 672056299  1767 IKEEREA 1773
Cdd:TIGR02168  977 LENKIKE 983
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1045-1982 4.13e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 4.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1045 RLQSTVKDLQQATSLLVLQGGCRATAGEEAEgngalSLLQQGEQLLEENGDVLISLQKAHERAVKENAKMATEISRlqqr 1124
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLR-----KMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---- 216
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1125 lkklEPGSAISSCLEERMTEISgssrehaepvmkrgtatkhFLSD---PGDHEAQGLGSTGTSSV----QRQECRTEE-- 1195
Cdd:pfam15921  217 ----SLGSAISKILRELDTEIS-------------------YLKGrifPVEDQLEALKSESQNKIelllQQHQDRIEQli 273
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1196 SEASLECFSELENSEDTRTESWDLKSQIIQLQEQLtvlRADCDRASERKRDLLFDISVLKKKLKMLERLpeasskykvlY 1275
Cdd:pfam15921  274 SEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA---RNQNSMYMRQLSDLESTVSQLRSELREAKRM----------Y 340
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1276 EDAAREnacLQEELRLMEMRYADSLDSNKELTAEVYRLQDEMKKM----------------------EEVTGTFLS---L 1330
Cdd:pfam15921  341 EDKIEE---LEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladlhkrekelslekeqnkrlwDRDTGNSITidhL 417
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1331 ENSYDEVKLENEKLSALVLRLQGKMEEVLER--AALQGDSYSLWEGPSENLEVTSDEKMLElhQTEEECTPEVMSRHHii 1408
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLKAMKSECQGQMERqmAAIQGKNESLEKVSSLTAQLESTKEMLR--KVVEELTAKKMTLES-- 493
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1409 eecrqetrcCEQGSTQLLAGIKAHEiawfrRKIE-THQEKPSVQNRVILE-ESAALLGLQGTHLQHEATIAE-LEL---E 1482
Cdd:pfam15921  494 ---------SERTVSDLTASLQEKE-----RAIEaTNAEITKLRSRVDLKlQELQHLKNEGDHLRNVQTECEaLKLqmaE 559
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1483 KQKLQELTRNLRERVTTLAKQ--KDAPSQGEEEEELKAVMHDlqitcgemqRKVELLRYESEKLQEENSILRneittlnE 1560
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQhgRTAGAMQVEKAQLEKEIND---------RRLELQEFKILKDKKDAKIRE-------L 623
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1561 EDSISNLKLEEL---NGSQEELwQKIETIEQEKASIQKMVEKLKKQVSDLklknqqldSENKELSQKNSQNK-EELKTln 1636
Cdd:pfam15921  624 EARVSDLELEKVklvNAGSERL-RAVKDIKQERDQLLNEVKTSRNELNSL--------SEDYEVLKRNFRNKsEEMET-- 692
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1637 qrlaemlcqkedpgtcTSEKWEQENESLKEELDrykvQTSTLVSSLEAElsevklQTHIVEQENLLLKDELERLKQLhrc 1716
Cdd:pfam15921  693 ----------------TTNKLKMQLKSAQSELE----QTRNTLKSMEGS------DGHAMKVAMGMQKQITAKRGQI--- 743
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1717 pdlSDFQQKMCSILSYNENLLKEKEVLSEElkscadklaeSSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLE 1796
Cdd:pfam15921  744 ---DALQSKIQFLEEAMTNANKEKHFLKEE----------KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1797 DILKNVNLQMAQIESDLQvtRQEKEalkqevmSLHLQLQNAIDkdwvsetathLSGLQGQQKRLSWNKLDHLMseEPELL 1876
Cdd:pfam15921  811 VALDKASLQFAECQDIIQ--RQEQE-------SVRLKLQHTLD----------VKELQGPGYTSNSSMKPRLL--QPASF 869
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1877 CQESKRLQTvVQNTQADLTHSREKIRQLESNllPTKHQKQLNQSCTVKPIEQEKLALKRECEQSRKERSPTSRKVSQMSS 1956
Cdd:pfam15921  870 TRTHSNVPS-SQSTASFLSHHSRKTNALKED--PTRDLKQLLQELRSVINEEPTVQLSKAEDKGRAPSLGALDDRVRDCI 946
                          970       980
                   ....*....|....*....|....*...
gi 672056299  1957 LEREL--ETIHLENEGLKKKQVRLDEKL 1982
Cdd:pfam15921  947 IESSLrsDICHSSSNSLQTEGSKSSETC 974
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1477-1801 4.59e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 4.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1477 AELELEK-----QKLQELTRNLRERVTTLAKQKDAPSQ----GEEEEELKAV-----MHDLQITCGEMQRKVELLRYESE 1542
Cdd:COG1196   177 AERKLEAteenlERLEDILGELERQLEPLERQAEKAERyrelKEELKELEAEllllkLRELEAELEELEAELEELEAELE 256
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1543 KLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELS 1622
Cdd:COG1196   257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1623 QKNSQNKEELKTLNQRLAEMLCQKEDpgtcTSEKWEQENESLKEELDRYKVQTSTLVSSLEAELSEVKLQTHIVEQENLL 1702
Cdd:COG1196   337 EELEELEEELEEAEEELEEAEAELAE----AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1703 LKDELERLKQLHRCPDlsdfqqkmcSILSYNENLLKEKEVLSEELKSCADKLAESSLLEHRIATIKEEREAWEEQSQDLK 1782
Cdd:COG1196   413 LERLERLEEELEELEE---------ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483
                         330
                  ....*....|....*....
gi 672056299 1783 SQLALSQEKVQNLEDILKN 1801
Cdd:COG1196   484 EELAEAAARLLLLLEAEAD 502
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
870-1642 8.24e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 8.24e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   870 RYRQELKDL--------LDQHLEERSQWEFEKDELTQECTEAQEQLEEV-------------LQREKATALARSQEQETL 928
Cdd:TIGR02168  217 ELKAELRELelallvlrLEELREELEELQEELKEAEEELEELTAELQELeekleelrlevseLEEEIEELQKELYALANE 296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   929 EKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQER-ELREPEHVLCQTGVSEQLG-SQQLARLQVE 1006
Cdd:TIGR02168  297 ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKlEELKEELESLEAELEELEAeLEELESRLEE 376
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1007 HEQERREMAGKIAALEsahrvsceradQEKAEMSAEIRRLQSTVKDLQQATSLLVLQGGCRATAGEEAEGNGALSLLQQG 1086
Cdd:TIGR02168  377 LEEQLETLRSKVAQLE-----------LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL 445
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1087 EQLLEEngdvlisLQKAHERAVKENAKMATEISRLQQRLKKLEPGSAISS----CLEERMTEISGSSREHAEPVMKR--- 1159
Cdd:TIGR02168  446 EEELEE-------LQEELERLEEALEELREELEEAEQALDAAERELAQLQarldSLERLQENLEGFSEGVKALLKNQsgl 518
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1160 ----GTATKHFLSDPGDHEA--QGLGSTGTSSVqrqecrTEESEASLECFSELENSEDTRteswdlksqiiqlqeqLTVL 1233
Cdd:TIGR02168  519 sgilGVLSELISVDEGYEAAieAALGGRLQAVV------VENLNAAKKAIAFLKQNELGR----------------VTFL 576
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1234 RADCDRASERKRDLLFDISVLKKKLKMLERLPEASSKYKVLYEDaarenaclqeelRLMEMRYADSLDSNKELTAEVYRL 1313
Cdd:TIGR02168  577 PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSY------------LLGGVLVVDDLDNALELAKKLRPG 644
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1314 Q-------DEMKKMEEVTGTFLSLENSYDEVKLENEKLSALVLRLQGKMEEvleraalqgdsyslwegpsenLEVTSDEK 1386
Cdd:TIGR02168  645 YrivtldgDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE---------------------LEKALAEL 703
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1387 MLELHQTEEEctpevmsrhhiIEECRQETRCCEQGSTQLLAGIKAHEiawfrRKIETHQEKPSVQNRVILEESAALLGLQ 1466
Cdd:TIGR02168  704 RKELEELEEE-----------LEQLRKELEELSRQISALRKDLARLE-----AEVEQLEERIAQLSKELTELEAEIEELE 767
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1467 GTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKQKDapsqgeeeeELKAVMHDLQITCGEMQRKVELLRYESEKLQE 1546
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD---------ELRAELTLLNEEAANLRERLESLERRIAATER 838
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1547 ENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNS 1626
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE 918
                          810
                   ....*....|....*.
gi 672056299  1627 QNKEELKTLNQRLAEM 1642
Cdd:TIGR02168  919 ELREKLAQLELRLEGL 934
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
636-963 8.29e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 8.29e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   636 EAELVIEQLKEQHHRdlchLRLELEDKVRhYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEIADLQGQAAV 715
Cdd:TIGR02169  188 RLDLIIDEKRQQLER----LRREREKAER-YQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   716 LKEAHHKASCRHEEEKKQLQMVFDEEKTQLQEELRleheqELKARLQQAEESFRQEREGLAQAAAwteekarsltrdleq 795
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIG-----ELEAEIASLERSIAEKERELEDAEE--------------- 322
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   796 sHQEQLLSLMEKHALEKEELRKELSEYHQR------ELQEGREEMEtECNRRVSQIEAQFQADCEKVTERcEQTLQSLeG 869
Cdd:TIGR02169  323 -RLAKLEAEIDKLLAEIEELEREIEEERKRrdklteEYAELKEELE-DLRAELEEVDKEFAETRDELKDY-REKLEKL-K 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   870 RYRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKThkerLAILSMEREQLLQD 949
Cdd:TIGR02169  399 REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL----AADLSKYEQELYDL 474
                          330
                   ....*....|....
gi 672056299   950 LKDLQNTSERQHSL 963
Cdd:TIGR02169  475 KEEYDRVEKELSKL 488
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1551-1840 1.26e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.54  E-value: 1.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1551 LRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKE 1630
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1631 ELKTLNQRLAEMLCQKEDpgtcTSEKWEQENESLKEELDRYKVQTSTLvSSLEAELSEVKLQTHIVEQENLLLKDELERL 1710
Cdd:TIGR02168  762 EIEELEERLEEAEEELAE----AEAEIEELEAQIEQLKEELKALREAL-DELRAELTLLNEEAANLRERLESLERRIAAT 836
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1711 KQLhrcpdlsdfqqkmcsilsyNENLLKEKEVLSEELKSCADKLAEsslLEHRIATIKEEREAWEEQSQDLKSQLALSQE 1790
Cdd:TIGR02168  837 ERR-------------------LEDLEEQIEELSEDIESLAAEIEE---LEELIEELESELEALLNERASLEEALALLRS 894
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 672056299  1791 KVQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQLQNAIDK 1840
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
1533-1984 1.75e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.12  E-value: 1.75e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1533 KVELLRYESEKLQEENSI--LRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQ------- 1603
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIdkFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKllklell 202
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1604 VSDLKLKNQ---QLDSENKELSQKNSQNKEELKTLNQRLAEM---LCQKEDPGTCTSEKWEQENESLKEELDRYKvQTST 1677
Cdd:TIGR04523  203 LSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKtteISNTQTQLNQLKDEQNKIKKQLSEKQKELE-QNNK 281
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1678 LVSSLEAELSEVKLQTHIVEQE-----NLLLKDELERLKQLHRC--PDLSDFQQKMCSILSYNENLLKEKEVLSEELKSC 1750
Cdd:TIGR04523  282 KIKELEKQLNQLKSEISDLNNQkeqdwNKELKSELKNQEKKLEEiqNQISQNNKIISQLNEQISQLKKELTNSESENSEK 361
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1751 ADKLAESsllEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSL 1830
Cdd:TIGR04523  362 QRELEEK---QNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1831 HLQLQNAIDKDWVsetathlsglqgqqKRLSWNKLDHLMSEEP---ELLCQESKRLQTVVQNTQADLTHSREKIRQLesn 1907
Cdd:TIGR04523  439 NSEIKDLTNQDSV--------------KELIIKNLDNTRESLEtqlKVLSRSINKIKQNLEQKQKELKSKEKELKKL--- 501
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672056299  1908 llpTKHQKQLNQscTVKPIEQEKLALKRECEQSRKERsptSRKVSQMSSLERELETIH--LENEGLKKKQVRLDEKLME 1984
Cdd:TIGR04523  502 ---NEEKKELEE--KVKDLTKKISSLKEKIEKLESEK---KEKESKISDLEDELNKDDfeLKKENLEKEIDEKNKEIEE 572
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1538-1860 1.98e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 1.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1538 RYESEKLQEensiLRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSE 1617
Cdd:TIGR02169  670 RSEPAELQR----LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED 745
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1618 NKELSQKNSQNKEELKTLNQRLAEMlcqkedpgTCTSEKWEQENESLKEELDRYKVQTST-LVSSLEAELSEVKLQTHIV 1696
Cdd:TIGR02169  746 LSSLEQEIENVKSELKELEARIEEL--------EEDLHKLEEALNDLEARLSHSRIPEIQaELSKLEEEVSRIEARLREI 817
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1697 EQE--NLLLKDELERLKQLHRCPDLSDFQQKMCSILSYNENLLKEKEVLSEELKSCADKLAEsslLEHRIATIKEEREAW 1774
Cdd:TIGR02169  818 EQKlnRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD---LESRLGDLKKERDEL 894
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1775 EEQ--------------SQDLKSQLALSQEKVQNLEDILKNVNLQMAQIES------DLQVTRQEKEALKQEVMSLHLQL 1834
Cdd:TIGR02169  895 EAQlrelerkieeleaqIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEipeeelSLEDVQAELQRVEEEIRALEPVN 974
                          330       340
                   ....*....|....*....|....*.
gi 672056299  1835 QNAIDKdwVSETATHLSGLQGQQKRL 1860
Cdd:TIGR02169  975 MLAIQE--YEEVLKRLDELKEKRAKL 998
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
657-1600 2.07e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.15  E-value: 2.07e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   657 LELEDKVRHYEKQLdhtrvacekeQVAMKQKYEQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQM 736
Cdd:TIGR02168  216 KELKAELRELELAL----------LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE 285
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   737 VFDEEKTQLQEELRLEHE-QELKARLQQAEESFRQEREGLAQAAAWTEEKARSLTRdleqsHQEQLLSLMEKHALEKEEL 815
Cdd:TIGR02168  286 LQKELYALANEISRLEQQkQILRERLANLERQLEELEAQLEELESKLDELAEELAE-----LEEKLEELKEELESLEAEL 360
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   816 RKELSEYHQRE--LQEGREEMETEcNRRVSQIEAQfQADCEKVTERCEQTLQSLEGRyRQELKDLLDQHLEERSqwEFEK 893
Cdd:TIGR02168  361 EELEAELEELEsrLEELEEQLETL-RSKVAQLELQ-IASLNNEIERLEARLERLEDR-RERLQQEIEELLKKLE--EAEL 435
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   894 DELTQECTEAQEQLEEVLQREKAtalarsqeqetlektHKERLAILSMEREQLLQDLKDLqntsERQHSLLSDQMLELKR 973
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELER---------------LEEALEELREELEEAEQALDAA----ERELAQLQARLDSLER 496
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   974 SQERELREPEHVLCQTGVSEQLGSQQLARLQVEHEQERREMAGKIAALESAHRVSCERADQEKaemsaeirrlqstvkdl 1053
Cdd:TIGR02168  497 LQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAK----------------- 559
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1054 qQATSLLVLQGGCRATAGEEAEGNGALSLLQQGEQLLEENG--DVLISLQKAHERAVK------ENAKMATEISRLQQRL 1125
Cdd:TIGR02168  560 -KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGflGVAKDLVKFDPKLRKalsyllGGVLVVDDLDNALELA 638
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1126 KKLEPGSAISScleermteisgssrEHAEPVMKRGTATKhflsdpgdheaqglGSTGTSSVqRQECRTEESEASlECFSE 1205
Cdd:TIGR02168  639 KKLRPGYRIVT--------------LDGDLVRPGGVITG--------------GSAKTNSS-ILERRREIEELE-EKIEE 688
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1206 LENSEDtrteswDLKSQIIQLQEQLTVLRADCDRASERKRDLLFDISVLKKKLKMLERLPEASSKykvLYEDAARENACL 1285
Cdd:TIGR02168  689 LEEKIA------ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE---RIAQLSKELTEL 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1286 QEELRLMEMRYADSLDSNKELTAEVYRLQDEMKKMEEvtgTFLSLENSYDEVKLENEKLSALVLRLQGKMEEVLERAALQ 1365
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE---ELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1366 GDSyslwegpsenlevtsdekMLELHQTEEECTPEVMSRHHIIEECRQetrcceqgstqllagikahEIAWFRRKIETHQ 1445
Cdd:TIGR02168  837 ERR------------------LEDLEEQIEELSEDIESLAAEIEELEE-------------------LIEELESELEALL 879
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1446 EKPSVQNRVILEESAALLGLqgthlqhEATIAELELEKQKLQELTRNLRERVTTLAKQKDApSQGEEEEELKAVMHDLQI 1525
Cdd:TIGR02168  880 NERASLEEALALLRSELEEL-------SEELRELESKRSELRRELEELREKLAQLELRLEG-LEVRIDNLQERLSEEYSL 951
                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672056299  1526 TCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKL 1600
Cdd:TIGR02168  952 TLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1437-1713 2.83e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 2.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1437 FRRKIETHQEKPSVQNRVILEESAALLGLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKQKDAPSQGEEEEEL 1516
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1517 KAVMHDLQITcgEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKM 1596
Cdd:TIGR02168  317 QLEELEAQLE--ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1597 VEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDPGTCTSEKWEQENESLKEELDRYKVQTS 1676
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474
                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 672056299  1677 TLVSSLEAELSEVKLQTHIVEQENLLLKDELERLKQL 1713
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKAL 511
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
390-1156 4.09e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 4.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   390 AALASFKAEIRHLLERVDQVVREKEKLRSDLDkaEKLKSLMASEVDDHHAaiERRNEYNLRKLDEEYKERIAAlKNELRQ 469
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIID--EKRQQLERLRREREKA--ERYQALLKEKREYEGYELLKE-KEALER 237
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   470 EREQILQQVGKQRVELEQ---EIEKAKTEENYIRDRLA-LSLKENNRLENELLENAEKLAEYENLTSKLQRSLEnVLAEK 545
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKlteEISELEKRLEEIEQLLEeLNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIA-EKERE 316
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   546 FGDLDPSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQnALSEELDGHGDGIEQDQEPGS 625
Cdd:TIGR02169  317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELE-EVDKEFAETRDELKDYREKLE 395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   626 GECNPLNMSIEAELVIEQLKEQHHRDLCHLRLELED-KVRHYEKQLDHTRVACE--------KEQVAMKQKYEQGMRTLE 696
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGiEAKINELEEEKEDKALEikkqewklEQLAADLSKYEQELYDLK 475
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   697 KQISELQSEIADLQGQAAVLkEAHHKASCRHEEEKKQLQMVFDE----------EKTQLQEELRLEHEQELKARLQ---- 762
Cdd:TIGR02169  476 EEYDRVEKELSKLQRELAEA-EAQARASEERVRGGRAVEEVLKAsiqgvhgtvaQLGSVGERYATAIEVAAGNRLNnvvv 554
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   763 -------QAEESFRQEREGLAQAAAWTeeKARSLTRDLEQSHQEQLLSLMEKHALEKEELRKELSEYHQ-----RELQEG 830
Cdd:TIGR02169  555 eddavakEAIELLKRRKAGRATFLPLN--KMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGdtlvvEDIEAA 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   831 REEM--------ETECNRRVSQIEAQFQADCEKVTERCEQTLQSLEGRYR-QELKDLLDQHLEERSQWEFEKDELTQECT 901
Cdd:TIGR02169  633 RRLMgkyrmvtlEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERlEGLKRELSSLQSELRRIENRLDELSQELS 712
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   902 EAQEQLEEVLQREKATALARSQEQETLEKThKERLAILSMEREQLLQDLKDLQntserqhSLLSDQMLELKRSQErELRE 981
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQEEEKLKERLEEL-EEDLSSLEQEIENVKSELKELE-------ARIEELEEDLHKLEE-ALND 783
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   982 PEHVLCQTGVseqlgsQQLARLQVEHEQERREMAGKIAALESA-HRVSCER--ADQEKAEMSAEIRRLQSTVKDLQQATS 1058
Cdd:TIGR02169  784 LEARLSHSRI------PEIQAELSKLEEEVSRIEARLREIEQKlNRLTLEKeyLEKEIQELQEQRIDLKEQIKSIEKEIE 857
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1059 LlvLQGGCRATAGEEAEGNGALSLLQQGEQLLEENGDVLISLQKAHERAVKEnakMATEISRLQQRLKKLEpgsAISSCL 1138
Cdd:TIGR02169  858 N--LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE---LEAQIEKKRKRLSELK---AKLEAL 929
                          810
                   ....*....|....*...
gi 672056299  1139 EERMTEISGSSREHAEPV 1156
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIP 947
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
385-926 5.19e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.85  E-value: 5.19e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  385 NGIHQAALasfKA-EIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMAS-----EVDDHHAAIERRNEyNLRKLDEEY-- 456
Cdd:COG4913   238 ERAHEALE---DArEQIELLEPIRELAERYAAARERLAELEYLRAALRLwfaqrRLELLEAELEELRA-ELARLEAELer 313
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  457 -KERIAALKNELRQEREQILQQVGKQRVELEQEIEKAKTEenyiRDRLALSLKENNRLENEL-LENAEKLAEYENLTSKL 534
Cdd:COG4913   314 lEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERE----LEERERRRARLEALLAALgLPLPASAEEFAALRAEA 389
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  535 QRSLENVlaekfgdldpsSAEFFLQEERLAQMRNEYEQqcrlLQDQVDELQSELEEYQAQG-----RVLRLpcQNALSEE 609
Cdd:COG4913   390 AALLEAL-----------EEELEALEEALAEAEAALRD----LRRELRELEAEIASLERRKsnipaRLLAL--RDALAEA 452
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  610 LdghgdGIEQDQEPgsgecnplnmsIEAELVieQLKEQHH-------RDLCHLRLEL------EDKVRHYEKQLdHTRVA 676
Cdd:COG4913   453 L-----GLDEAELP-----------FVGELI--EVRPEEErwrgaieRVLGGFALTLlvppehYAAALRWVNRL-HLRGR 513
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  677 CEKEQVAMKQKYEQGMRTLEKQISE------------LQSEIADLQGQAAVLKEA----HHKA----------SCRHE-- 728
Cdd:COG4913   514 LVYERVRTGLPDPERPRLDPDSLAGkldfkphpfrawLEAELGRRFDYVCVDSPEelrrHPRAitragqvkgnGTRHEkd 593
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  729 ---EEKKQLQMVFD-----EEKTQLQEELRLEHE--QELKARLQQAEESFRQEREGLAQAA--AWTEEKARSLTRDLEQs 796
Cdd:COG4913   594 drrRIRSRYVLGFDnraklAALEAELAELEEELAeaEERLEALEAELDALQERREALQRLAeySWDEIDVASAEREIAE- 672
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  797 hQEQLLSLMEKHALEKEELRKELSEyHQRELQEGREEMEtECNRRVSQIEAQfQADCEKVTERCEQTLQSLEGRYRQELK 876
Cdd:COG4913   673 -LEAELERLDASSDDLAALEEQLEE-LEAELEELEEELD-ELKGEIGRLEKE-LEQAEEELDELQDRLEAAEDLARLELR 748
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|
gi 672056299  877 DLLDQHLEERSQWEFEKdeltqectEAQEQLEEvlQREKATALARSQEQE 926
Cdd:COG4913   749 ALLEERFAAALGDAVER--------ELRENLEE--RIDALRARLNRAEEE 788
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
389-986 6.08e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.62  E-value: 6.08e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   389 QAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEyNLRKLDEEYKERIAALkNELR 468
Cdd:TIGR02169  293 KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERK-RRDKLTEEYAELKEEL-EDLR 370
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   469 QEREQILQQVGKQRVEL---EQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLENV---L 542
Cdd:TIGR02169  371 AELEEVDKEFAETRDELkdyREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKaleI 450
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   543 AEKFGDLDPSSAEFFLQEERLAQMRNEYEQqcrlLQDQVDELQSELEEYQAQGRVLR--LPCQNALSEELDGHGDGI--- 617
Cdd:TIGR02169  451 KKQEWKLEQLAADLSKYEQELYDLKEEYDR----VEKELSKLQRELAEAEAQARASEerVRGGRAVEEVLKASIQGVhgt 526
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   618 --------EQDQEP----GSGECNplNMSIEAELV----IEQLKE---------------QHHRDLCHLRL--------- 657
Cdd:TIGR02169  527 vaqlgsvgERYATAievaAGNRLN--NVVVEDDAVakeaIELLKRrkagratflplnkmrDERRDLSILSEdgvigfavd 604
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   658 --ELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEI-------ADLQGQAAVLKEAHHKASCRHE 728
Cdd:TIGR02169  605 lvEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGELFEKSGAMtggsrapRGGILFSRSEPAELQRLRERLE 684
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   729 EEKKQLQMVFDE------EKTQLQEELRLEHEQ--ELKARLQQAEESFRQEREGLAQAAAWTEEKARSLTRDleQSHQEQ 800
Cdd:TIGR02169  685 GLKRELSSLQSElrrienRLDELSQELSDASRKigEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV--KSELKE 762
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   801 LLSLMEKHALEKEELRKELSEYHQRELQEGREEMETEcnrrVSQIEAQFQaDCEKVTERCEQTLQSLEGRyRQELKDLLD 880
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAE----LSKLEEEVS-RIEARLREIEQKLNRLTLE-KEYLEKEIQ 836
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   881 QHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKTHKER------LAILSMEREQL---LQDLK 951
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERdeleaqLRELERKIEELeaqIEKKR 916
                          650       660       670
                   ....*....|....*....|....*....|....*
gi 672056299   952 DLQNTSERQHSLLSDQMLELKRSQERELREPEHVL 986
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEEIPEEEL 951
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1424-1709 1.08e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 1.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1424 QLLAGIKAHEIAWFRRKIETHQEKPSVQNRVILEESAALLGLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKQ 1503
Cdd:COG1196   224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQD 303
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1504 KD-----APSQGEEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEE 1578
Cdd:COG1196   304 IArleerRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1579 LWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMlcqkedpgtctsEKWE 1658
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA------------AEEE 451
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 672056299 1659 QENESLKEELDRYKVQTSTLVSSLEAELSEVKLQTHIVEQENLLLKDELER 1709
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1453-1802 2.72e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 2.72e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1453 RVILEESAALLGLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKQKdapSQGEEEEELKAVMHDLQITC----- 1527
Cdd:TIGR02168  158 RAIFEEAAGISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQA---EKAERYKELKAELRELELALlvlrl 234
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1528 GEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDL 1607
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1608 KLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDpgtctSEKWEQENESLKEELDRYKVQTSTLVSSLEAELS 1687
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES-----LEAELEELEAELEELESRLEELEEQLETLRSKVA 389
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1688 EVKLQTHIVEQENLLLKDELERLKqlHRCPDLSDFQQKMCSILSYNEnLLKEKEVLSEELKSCADKLAESSLLEHRIATI 1767
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLE--DRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEELQEELERLEEALEEL 466
                          330       340       350
                   ....*....|....*....|....*....|....*
gi 672056299  1768 KEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNV 1802
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSLERLQENL 501
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
433-1232 4.56e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 4.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   433 EVDDHHAAIERRNEYNLRKLDEEYKERIAALK------NELRQEREQILQQVGKQRVELEQEIEKAKTEENYIRDRLALS 506
Cdd:pfam15921   60 ELDSPRKIIAYPGKEHIERVLEEYSHQVKDLQrrlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQS 139
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   507 LKE-NNRLENEL--LENAEKLAE--YENLTSKLQR------SLENVLAEKFG---DLDPSSAEFFLQEERLAQMR----- 567
Cdd:pfam15921  140 QEDlRNQLQNTVheLEAAKCLKEdmLEDSNTQIEQlrkmmlSHEGVLQEIRSilvDFEEASGKKIYEHDSMSTMHfrslg 219
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   568 NEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNALSEELDGHGDGIEQ------------DQEPGSGECNPLNMSI 635
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQliseheveitglTEKASSARSQANSIQS 299
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   636 EAELVIEQLKEQHHRDLCHLRlELEDKVRHYEKQLDHTrvacekeqvamKQKYEQGMRTLEKQISELQSEIADlqgqaav 715
Cdd:pfam15921  300 QLEIIQEQARNQNSMYMRQLS-DLESTVSQLRSELREA-----------KRMYEDKIEELEKQLVLANSELTE------- 360
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   716 lkeahhkasCRHEEEKkqlqmvFDEEKTQLQEELrleheQELKARLQQAEESFRQEREglAQAAAWTEEKARSLTRD-LE 794
Cdd:pfam15921  361 ---------ARTERDQ------FSQESGNLDDQL-----QKLLADLHKREKELSLEKE--QNKRLWDRDTGNSITIDhLR 418
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   795 QSHQEQLLSLMEKHALEKeELRKELSeyHQRELQEGREEMETECNRRVSQIEAQFQADCE---KVTERCEQTLQSLEGRY 871
Cdd:pfam15921  419 RELDDRNMEVQRLEALLK-AMKSECQ--GQMERQMAAIQGKNESLEKVSSLTAQLESTKEmlrKVVEELTAKKMTLESSE 495
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   872 RQeLKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEV--LQREKATALARSQEQETLEKTHKERLAILSMEREQlLQD 949
Cdd:pfam15921  496 RT-VSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELqhLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQ-IEN 573
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   950 LKDLQNtserQHSLLSDQMLELKRSQERELREpehvlcqtgvsEQLGSQQLARLQVEHEQERREMAGKIAALE------- 1022
Cdd:pfam15921  574 MTQLVG----QHGRTAGAMQVEKAQLEKEIND-----------RRLELQEFKILKDKKDAKIRELEARVSDLElekvklv 638
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1023 ---SAHRVSCERADQEKAEMSAEIRRLQSTVKDLQQATSllVLQGGCRATAGE-EAEGNGALSLLQQGEQLLEENGDVLI 1098
Cdd:pfam15921  639 nagSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE--VLKRNFRNKSEEmETTTNKLKMQLKSAQSELEQTRNTLK 716
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1099 SLQKAHERAVKENAKMATEISRLQQRLKKLEpgsaisscleermteisgSSREHAEPVMKRGTATKHFLSDPGDHEAQGL 1178
Cdd:pfam15921  717 SMEGSDGHAMKVAMGMQKQITAKRGQIDALQ------------------SKIQFLEEAMTNANKEKHFLKEEKNKLSQEL 778
                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672056299  1179 GSTGTSS---------VQRQECRTEESEASLECfsELENSEDTRTESWDlksqIIQLQEQLTV 1232
Cdd:pfam15921  779 STVATEKnkmagelevLRSQERRLKEKVANMEV--ALDKASLQFAECQD----IIQRQEQESV 835
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
689-1129 6.01e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 6.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  689 EQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQMVFDEEKTQLQEEL---------RLEHEQELKA 759
Cdd:COG4913   287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIerlereleeRERRRARLEA 366
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  760 RLQQAEESFRQEREGLAQAAAWTEEKARSLTRDLEQSHQEQLLSLMEKHALEKE--ELRKELSEYHQR------ELQEGR 831
Cdd:COG4913   367 LLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRElrELEAEIASLERRksnipaRLLALR 446
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  832 EEMETECNrrVSQIEAQFQADCEKVTERCEQTLQSLEG-------------RYRQELKDLLDQ-HLEERSQWEFEK---- 893
Cdd:COG4913   447 DALAEALG--LDEAELPFVGELIEVRPEEERWRGAIERvlggfaltllvppEHYAAALRWVNRlHLRGRLVYERVRtglp 524
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  894 -------------DELTQECTEAQEQLEEVLQREKATALARSQEQetLEKTHK--------------------------- 933
Cdd:COG4913   525 dperprldpdslaGKLDFKPHPFRAWLEAELGRRFDYVCVDSPEE--LRRHPRaitragqvkgngtrhekddrrrirsry 602
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  934 -------ERLAILSMEREQL---LQDLKDLQNTSERQHSLLSDQMLELKRSQERELREPEHVLCQTGVSEQlgSQQLARL 1003
Cdd:COG4913   603 vlgfdnrAKLAALEAELAELeeeLAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAEL--EAELERL 680
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1004 QVEHeQERREMAGKIAALESAHrvscERADQEKAEMSAEIRRLQSTVKDLQQatsllvLQGGCRATAgEEAEGNGALSLL 1083
Cdd:COG4913   681 DASS-DDLAALEEQLEELEAEL----EELEEELDELKGEIGRLEKELEQAEE------ELDELQDRL-EAAEDLARLELR 748
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 672056299 1084 QQGEQLLEENgdvlisLQKAHERAVKENakMATEISRLQQRLKKLE 1129
Cdd:COG4913   749 ALLEERFAAA------LGDAVERELREN--LEERIDALRARLNRAE 786
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
903-1641 9.85e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 9.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   903 AQEQLEEVLQREKatalarsqEQETLEKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQERELRep 982
Cdd:TIGR02169  175 ALEELEEVEENIE--------RLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIER-- 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   983 ehvlcqtgvseqlgsqQLARLQVEHEQERREMAGKIAALESAHRVSCERADQEKAEMSAEIRRLQSTVKDLQQATSLLVl 1062
Cdd:TIGR02169  245 ----------------QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLE- 307
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1063 qggcRATAGEEAEGNGALSLLQQGEQLLEENGDVLISLQKAHERAVKENAKMATEISRLQQRLKKlepgsaisscLEERM 1142
Cdd:TIGR02169  308 ----RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELED----------LRAEL 373
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1143 TEISGSSREHAEPVMKRGTATKHFLSDPGDHeaQGLGSTGTSSVQRQECRTEESEASLECFSELENSEDTRTEswDLKSQ 1222
Cdd:TIGR02169  374 EEVDKEFAETRDELKDYREKLEKLKREINEL--KRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKE--DKALE 449
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1223 IIQLQEQLTVLRADCDRASERKRDLLFDISVLKKKLKMLERLPEASSKYKVLYEDAARENACLQEELRL----------- 1291
Cdd:TIGR02169  450 IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAsiqgvhgtvaq 529
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1292 ---MEMRYADSLDSNKELTAEVYRLQDE---------MKKMEEVTGTFLSL-----ENSYDEVKLEN------------- 1341
Cdd:TIGR02169  530 lgsVGERYATAIEVAAGNRLNNVVVEDDavakeaielLKRRKAGRATFLPLnkmrdERRDLSILSEDgvigfavdlvefd 609
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1342 ---EKLSALVLRLQGKME-------------------EVLERA-ALQGDSYSLWEGPSENLEVTSDEKML-----ELHQT 1393
Cdd:TIGR02169  610 pkyEPAFKYVFGDTLVVEdieaarrlmgkyrmvtlegELFEKSgAMTGGSRAPRGGILFSRSEPAELQRLrerleGLKRE 689
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1394 EEECTPEVMSRHHIIEECRQETRCCEQ--GSTQLLAGIKAHEIAWFRRKIETHQEKPSVQNRVILEESAALLGLQGTHLQ 1471
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSDASRkiGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEE 769
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1472 HEATIAELELEKQKLQEltRNLRERVTTLAKQKDapSQGEEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQEENSIL 1551
Cdd:TIGR02169  770 LEEDLHKLEEALNDLEA--RLSHSRIPEIQAELS--KLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1552 RNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEE 1631
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925
                          810
                   ....*....|
gi 672056299  1632 LKTLNQRLAE 1641
Cdd:TIGR02169  926 LEALEEELSE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1476-1835 1.15e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.15e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1476 IAELELEKQKLQELTRNLRERVTTLAKQKDapsQGEEEEELKAVMHDLQITcgEMQRKVELLRYESEKLQEENSILRNEI 1555
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLRRERE---KAERYQALLKEKREYEGY--ELLKEKEALERQKEAIERQLASLEEEL 253
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1556 TTLNEEDSISNLKLEELNGSQEELWQKIETI-EQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELkt 1634
Cdd:TIGR02169  254 EKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI-- 331
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1635 lnqrlaemlcqkedpgtctsEKWEQENESLKEELDRYKVQTSTL---VSSLEAELSEVKLQTHIVEQENLLLKDELERLK 1711
Cdd:TIGR02169  332 --------------------DKLLAEIEELEREIEEERKRRDKLteeYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1712 QlhrcpDLSDFQQKMCSILSYNENLLKEKEVLSEELkscadklaesSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEK 1791
Cdd:TIGR02169  392 E-----KLEKLKREINELKRELDRLQEELQRLSEEL----------ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK 456
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 672056299  1792 VQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQLQ 1835
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
1531-1802 1.86e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.57  E-value: 1.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1531 QRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQvsdLKLK 1610
Cdd:TIGR04523  418 QQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKE---LKSK 494
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1611 NQQLD---SENKELSQKNSQNKEELKTLNQRLAEMlcqkedpgtcTSEKWEQENE--SLKEELDrykvqtstlvsSLEAE 1685
Cdd:TIGR04523  495 EKELKklnEEKKELEEKVKDLTKKISSLKEKIEKL----------ESEKKEKESKisDLEDELN-----------KDDFE 553
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1686 LSEVKLQTHIVEQENlllkdELERLKQLHRCPDLSDFQQkmcsilsynENLLKEKEVLSEELKS-CADKLAESSLLEHRI 1764
Cdd:TIGR04523  554 LKKENLEKEIDEKNK-----EIEELKQTQKSLKKKQEEK---------QELIDQKEKEKKDLIKeIEEKEKKISSLEKEL 619
                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 672056299  1765 ATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNV 1802
Cdd:TIGR04523  620 EKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEI 657
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
720-1026 5.22e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 54.74  E-value: 5.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   720 HHKASCRHEEEKKQLQMvfdEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEEKARSLTRDLEQSHQE 799
Cdd:pfam17380  280 HQKAVSERQQQEKFEKM---EQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQE 356
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   800 QLLSLMEKhaLEKEELRKELSEYH-------QRELQEGREEMETECNRRVSQIEAQFQADCEKVTERCEQTLQSLEGRYR 872
Cdd:pfam17380  357 ERKRELER--IRQEEIAMEISRMRelerlqmERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ 434
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   873 QELkdlldQHLEERSQWEFEKdeLTQECTEAQEQLEEVLQRE---KATALARSQEQETLEKTHKERLAILSMEREQLLQD 949
Cdd:pfam17380  435 REV-----RRLEEERAREMER--VRLEEQERQQQVERLRQQEeerKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA 507
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   950 LKDLQN--------TSERQHSLLSDQMlelKRSQERELREPEHVLCQTGVSEQLGSQQLARLQVEHEQERREMAGKIAAL 1021
Cdd:pfam17380  508 MIEEERkrkllekeMEERQKAIYEEER---RREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVES 584

                   ....*
gi 672056299  1022 ESAHR 1026
Cdd:pfam17380  585 EKARA 589
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
389-594 5.58e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 5.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  389 QAALASFKAEIRHLLERVDQVVREKEKLRSDLDkaeklkslmasEVDDHHAAIERRNEYNLRKLD-EEYKERIAALKNEL 467
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELD-----------ALQERREALQRLAEYSWDEIDvASAEREIAELEAEL 677
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  468 RQERE--QILQQVGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLenvLAEK 545
Cdd:COG4913   678 ERLDAssDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL---LEER 754
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 672056299  546 FGDLdpssaeffLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQ 594
Cdd:COG4913   755 FAAA--------LGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1242-1985 7.74e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.68  E-value: 7.74e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1242 ERKRDLLFDisvLKKKLKMLERLPEASSKYKVLYED--------AARENACLQEELRLMEMRYADSLDSNKELTAEVYRL 1313
Cdd:TIGR02168  189 DRLEDILNE---LERQLKSLERQAEKAERYKELKAElrelelalLVLRLEELREELEELQEELKEAEEELEELTAELQEL 265
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1314 QdemKKMEEVTGTFLSLENSYDEVKLENEKLSALVLRLQGKMEEVLERAALQGDSYSLWEGPSENLEVTSDEKMLELHQT 1393
Cdd:TIGR02168  266 E---EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1394 EEEctpevmsrhhiIEECRQEtrcceqgstqlLAGIKAhEIAWFRRKIETHQEKPSVQNRVILEESAALLGLQGTHLQHE 1473
Cdd:TIGR02168  343 EEK-----------LEELKEE-----------LESLEA-ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1474 ATIAELELEKQKLQELTRNLRERVTTLAKQKDAPS---QGEEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQEENSI 1550
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkeLQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1551 LRNEITTLNEE---------------DSISNLKL--EELNGSQEELWQKIETIEQ-EKA-------SIQKMV----EKLK 1601
Cdd:TIGR02168  480 AERELAQLQARldslerlqenlegfsEGVKALLKnqSGLSGILGVLSELISVDEGyEAAieaalggRLQAVVvenlNAAK 559
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1602 KQVSDLKLKNQQ------LDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDP----------GTCTSEKWEQENESLK 1665
Cdd:TIGR02168  560 KAIAFLKQNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllgGVLVVDDLDNALELAK 639
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1666 EELDRYK-------------------VQTSTLVSSLEAELSEVKLQTHIVEQENLLLKDELERLKQlhrcpDLSDFQQKM 1726
Cdd:TIGR02168  640 KLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK-----ELEELEEEL 714
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1727 CSILSYNENLLKEkevLSEELKSCADKLAESSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQM 1806
Cdd:TIGR02168  715 EQLRKELEELSRQ---ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI 791
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1807 AQIESDLQVTRQEKEALKQEVMSLHLQLQNAidkdwvsetathLSGLQGQQKRLswnkldHLMSEEPELLCQESKRLQTV 1886
Cdd:TIGR02168  792 EQLKEELKALREALDELRAELTLLNEEAANL------------RERLESLERRI------AATERRLEDLEEQIEELSED 853
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1887 VQNTQADLTHSREKIRQLESNLlpTKHQKQLNQsctvkpIEQEKLALKRECEQSRKERSPTSRKVS----QMSSLERELE 1962
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESEL--EALLNERAS------LEEALALLRSELEELSEELRELESKRSelrrELEELREKLA 925
                          810       820
                   ....*....|....*....|...
gi 672056299  1963 TIHLENEGLKKKQVRLDEKLMEN 1985
Cdd:TIGR02168  926 QLELRLEGLEVRIDNLQERLSEE 948
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
695-925 1.08e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.87  E-value: 1.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  695 LEKQISELQSEIADLQGQAAVLKEAHhkascrheeekkqLQMVFDEEKTQLQEELrleheQELKARLQQAEESFRQEREG 774
Cdd:COG3206   180 LEEQLPELRKELEEAEAALEEFRQKN-------------GLVDLSEEAKLLLQQL-----SELESQLAEARAELAEAEAR 241
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  775 LAQAAAWTEEKARSLTRDLEQSHQEQLLSLMEKHALEKEELRKELSEYH------QRELQEGREEMETECNRRVSQIEAQ 848
Cdd:COG3206   242 LAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHpdvialRAQIAALRAQLQQEAQRILASLEAE 321
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672056299  849 FQAdcekvTERCEQTLQSLEGRYRQELKDLldqhleerSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQ 925
Cdd:COG3206   322 LEA-----LQAREASLQAQLAQLEARLAEL--------PELEAELRRLEREVEVARELYESLLQRLEEARLAEALTV 385
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
1531-1840 1.33e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1531 QRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQ---------------------- 1588
Cdd:TIGR04523  292 QLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKeltnsesensekqreleekqne 371
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1589 ------EKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDPGTCTSEKWEQEN- 1661
Cdd:TIGR04523  372 ieklkkENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSv 451
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1662 -ESLKEELDRYKVQTSTLVSSLEAELSEVKLQTHIVEQENLLLKDELERLKQLHRCPD--LSDFQQKMCSILSYNENLLK 1738
Cdd:TIGR04523  452 kELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEekVKDLTKKISSLKEKIEKLES 531
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1739 EKEVLSEELKSCADKLAE------SSLLEHRIATIKEEREAW---------------------EEQSQDLKSQLALSQEK 1791
Cdd:TIGR04523  532 EKKEKESKISDLEDELNKddfelkKENLEKEIDEKNKEIEELkqtqkslkkkqeekqelidqkEKEKKDLIKEIEEKEKK 611
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 672056299  1792 VQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQLQNAIDK 1840
Cdd:TIGR04523  612 ISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1575-1862 1.37e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 1.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1575 SQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMlcqkedpgtcts 1654
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAEL------------ 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1655 ekwEQENESLKEELDRYKVQTSTLVSSLEaelsevklQTHIVEQENLLLKDElerlkqlhrcpDLSDFQQKMCSILSYNE 1734
Cdd:COG4942    89 ---EKEIAELRAELEAQKEELAELLRALY--------RLGRQPPLALLLSPE-----------DFLDAVRRLQYLKYLAP 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1735 NLLKEKEVLSEELkscadklaessllehriATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQ 1814
Cdd:COG4942   147 ARREQAEELRADL-----------------AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELA 209
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 672056299 1815 VTRQEKEALKQEVMSLHLQLQNAIDKDWVSETATHLSGLQGQQKRLSW 1862
Cdd:COG4942   210 ELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKLPW 257
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
398-611 1.75e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 53.01  E-value: 1.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  398 EIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALkNELRQEREQILQQ 477
Cdd:PRK05771   44 RLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEI-SELENEIKELEQE 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  478 vgKQRVE----LEQEIEKAKTEENYIrdRLALSLKENNRLENELLENAEKLAEYENLTSKL------QRSLENVLAEKFG 547
Cdd:PRK05771  123 --IERLEpwgnFDLDLSLLLGFKYVS--VFVGTVPEDKLEELKLESDVENVEYISTDKGYVyvvvvvLKELSDEVEEELK 198
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672056299  548 DLDPSSAEFFlQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNALSEELD 611
Cdd:PRK05771  199 KLGFERLELE-EEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELE 261
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
766-1646 2.26e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.05  E-value: 2.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   766 ESFRQEREGLAQAAAWTEEKARSLTRDLEQSHQEQLLSLMEKHALEKEELRKELSEYHQRELQEGREEMETECNRRVSQI 845
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   846 EAqfqadcekvTERCEQTLQSLEGRYRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQ 925
Cdd:pfam02463  246 LR---------DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKL 316
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   926 ETLEKTHKERLAILSMEREQLLQDLKDLQNtSERQHSLLSDQMLELKRSQERELREPEHVLcqtgVSEQLGSQQLARLQV 1005
Cdd:pfam02463  317 KESEKEKKKAEKELKKEKEEIEELEKELKE-LEIKREAEEEEEEELEKLQEKLEQLEEELL----AKKKLESERLSSAAK 391
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1006 EHEQERREMAGKIAALESAHRVSCERADQEKAEMSAEIRRLQSTVKDLqqatsllvlqggcratagEEAEGNGALSLLQQ 1085
Cdd:pfam02463  392 LKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI------------------ELKQGKLTEEKEEL 453
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1086 GEQLLEENGDVLISLQKAHERAVKENAKMATEISRLQQRLKKLEPGSAISSCLEERMTEISGSSRehaePVMKRGTATKH 1165
Cdd:pfam02463  454 EKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKD----GVGGRIISAHG 529
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1166 FLSDPGDHEAQGLGSTGTSSVQRQECRTEESEASLECFSELENSED----TRTESWDLKSQIIQLQEQLTVLRADCDRAS 1241
Cdd:pfam02463  530 RLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLgarkLRLLIPKLKLPLKSIAVLEIDPILNLAQLD 609
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1242 ERKRDLLFDISVLKKKLKMLERLPEASSKYKVLYEDAARENACLQEELRLMEMRYadsldsNKELTAEVYRLQDEMKKME 1321
Cdd:pfam02463  610 KATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV------KASLSELTKELLEIQELQE 683
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1322 EVTGTFLSLENSYDEVKLENEKLSALVLRLQGKMEEVLERAALQGDSYSLWEGPSENLEVTSDEKMLELHQTEEECTPEV 1401
Cdd:pfam02463  684 KAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKE 763
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1402 MSRHHIIEecrQETRCCEQGSTQLLAGIKAHEIAWFRRKIETHQEKPSVQNRVILEESAALLGLQGTHLQHEATIAELEL 1481
Cdd:pfam02463  764 EEKSELSL---KEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELAL 840
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1482 EKQKLQELTRNLRERVTTLAK--QKDAPSQGEEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLN 1559
Cdd:pfam02463  841 ELKEEQKLEKLAEEELERLEEeiTKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIE 920
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1560 EEDSISNLKLEELNGSQEELW-----------QKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQN 1628
Cdd:pfam02463  921 ERIKEEAEILLKYEEEPEELLleeadekekeeNNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERL 1000
                          890
                   ....*....|....*...
gi 672056299  1629 KEELKTLNQRLAEMLCQK 1646
Cdd:pfam02463 1001 EEEKKKLIRAIIEETCQR 1018
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
468-912 2.29e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.03  E-value: 2.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  468 RQEREQILQQVGKQRVELeQEIEKAKTEENYIRDRLALSLKENNRLENELLenaeklAEYENLTSKLQRSLENV-LAEKF 546
Cdd:COG3096   277 ANERRELSERALELRREL-FGARRQLAEEQYRLVEMARELEELSARESDLE------QDYQAASDHLNLVQTALrQQEKI 349
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  547 G--DLDPSSAEFFLQE-----ERLAQMRNEYEQQCRLLQDQVDELQSELEEYQA-----QGRVLRLpcQNALseeldghg 614
Cdd:COG3096   350 EryQEDLEELTERLEEqeevvEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQaldvqQTRAIQY--QQAV-------- 419
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  615 dgieQDQEPGSGECNplnmsiEAELVIEQLKEQHHRDLCHLRlELEDKVRHYEKQLDHTRVAcekeqvamKQKYEQGMRT 694
Cdd:COG3096   420 ----QALEKARALCG------LPDLTPENAEDYLAAFRAKEQ-QATEEVLELEQKLSVADAA--------RRQFEKAYEL 480
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  695 LEKQISELQSEIADLQGQAAVlkeahhkasCRHEEEKKQLQMVfdeektqlqeelrleheQELKARLQQAEESFRQEREg 774
Cdd:COG3096   481 VCKIAGEVERSQAWQTARELL---------RRYRSQQALAQRL-----------------QQLRAQLAELEQRLRQQQN- 533
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  775 laqaaawteekARSLTRDLEQSHQEQLLS--LMEKHALEKEELRKELSEYhQRELQEGREEMETE---CNRRVSQIEAQ- 848
Cdd:COG3096   534 -----------AERLLEEFCQRIGQQLDAaeELEELLAELEAQLEELEEQ-AAEAVEQRSELRQQleqLRARIKELAARa 601
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672056299  849 ---FQADcEKVTERCEQTLQSLEGryRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQ 912
Cdd:COG3096   602 pawLAAQ-DALERLREQSGEALAD--SQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQ 665
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
701-930 2.41e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  701 ELQSEIADLQGQAAVLKEAHHKAscrhEEEKKQLQmvfdeektqlqeelRLEHEQELKARLQQAEESFRQEREGLAQAAA 780
Cdd:COG4913   222 DTFEAADALVEHFDDLERAHEAL----EDAREQIE--------------LLEPIRELAERYAAARERLAELEYLRAALRL 283
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  781 WTEEKARSLTRDLEQSHQEQLLSLMEKHAL---EKEELRKELSEYHQRELQEGREEMEtECNRRVSQIEAQfQADCEKVT 857
Cdd:COG4913   284 WFAQRRLELLEAELEELRAELARLEAELERleaRLDALREELDELEAQIRGNGGDRLE-QLEREIERLERE-LEERERRR 361
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672056299  858 ERCEQTLQSLEGRY---RQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEvLQREKATAlarSQEQETLEK 930
Cdd:COG4913   362 ARLEALLAALGLPLpasAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRD-LRRELREL---EAEIASLER 433
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
434-930 2.72e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 2.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   434 VDDHHAAIERRNEYNlrkldeeYKERIAALKNEL----------RQEREQILQQVGKQRVELEQEIEKAKTEEnyirdrl 503
Cdd:TIGR02168  628 VDDLDNALELAKKLR-------PGYRIVTLDGDLvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKI------- 693
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   504 alslkenNRLENELLENAEKLAEYENLTSKLQRslenvlaekfgDLDPSSAEFFLQEERLAQMRNEYEQqcrlLQDQVDE 583
Cdd:TIGR02168  694 -------AELEKALAELRKELEELEEELEQLRK-----------ELEELSRQISALRKDLARLEAEVEQ----LEERIAQ 751
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   584 LQSELEEYQAQgRVLRLPCQNALSEELDGHGDGIEQDQEPgsgecnPLNMSIEAELVIEQLKEQhHRDLCHLRLELEDKV 663
Cdd:TIGR02168  752 LSKELTELEAE-IEELEERLEEAEEELAEAEAEIEELEAQ------IEQLKEELKALREALDEL-RAELTLLNEEAANLR 823
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   664 RHYEkQLDHTRVACEKEQVAMKQKYEQgmrtLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQMVFDEEKT 743
Cdd:TIGR02168  824 ERLE-SLERRIAATERRLEDLEEQIEE----LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE 898
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   744 QLQEELRLEHE-QELKARLQQAEESFRQEREGLAQaaawteekarsltrdLEQSHQEQLLSLMEKHALEKEELrkelsey 822
Cdd:TIGR02168  899 LSEELRELESKrSELRRELEELREKLAQLELRLEG---------------LEVRIDNLQERLSEEYSLTLEEA------- 956
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   823 hqRELQEGREEMETECNRRVSQIEAQFQADCEkVTERCEQTLQSLEGRYrqelkdlldQHLEErsqwefEKDELtqecTE 902
Cdd:TIGR02168  957 --EALENKIEDDEEEARRRLKRLENKIKELGP-VNLAAIEEYEELKERY---------DFLTA------QKEDL----TE 1014
                          490       500
                   ....*....|....*....|....*...
gi 672056299   903 AQEQLEEVLqrEKATALARSQEQETLEK 930
Cdd:TIGR02168 1015 AKETLEEAI--EEIDREARERFKDTFDQ 1040
mukB PRK04863
chromosome partition protein MukB;
444-914 2.90e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 52.65  E-value: 2.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  444 RNEYNLRKLDEEykerIAALKNELRQEREQI-------------LQQVGKQRVELEQEIEKAkteenyiRDRLALSlken 510
Cdd:PRK04863  276 RHANERRVHLEE----ALELRRELYTSRRQLaaeqyrlvemareLAELNEAESDLEQDYQAA-------SDHLNLV---- 340
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  511 nrleNELLENAEKLAEYENLTSKLQRSLEnvlaekfgdldpsSAEFFLQEerLAQMRNEYEQQCRLLQDQVDELQSELEE 590
Cdd:PRK04863  341 ----QTALRQQEKIERYQADLEELEERLE-------------EQNEVVEE--ADEQQEENEARAEAAEEEVDELKSQLAD 401
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  591 YQ-----AQGRVLRLpcQNALseeldghgdgieQDQEPGSGECNPLNMSIE-AELVIEQLKEQHHrdlchlrlELEDKVR 664
Cdd:PRK04863  402 YQqaldvQQTRAIQY--QQAV------------QALERAKQLCGLPDLTADnAEDWLEEFQAKEQ--------EATEELL 459
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  665 HYEKQLDHTRVAcekeqvamKQKYEQGMRTLEKQISELQSEIADLQGQAAVLkeahhkascRHEEEKKQLQMVfdeektq 744
Cdd:PRK04863  460 SLEQKLSVAQAA--------HSQFEQAYQLVRKIAGEVSRSEAWDVARELLR---------RLREQRHLAEQL------- 515
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  745 lqeelrleheQELKARLQQAEESFRQEREglaqaaawteekARSLTRDLEQSHQEQLLS--LMEKHALEKEELRKELSEY 822
Cdd:PRK04863  516 ----------QQLRMRLSELEQRLRQQQR------------AERLLAEFCKRLGKNLDDedELEQLQEELEARLESLSES 573
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  823 hQRELQEGREEMETECN------RRVSQIEAQFQADCEKVTERCEQTLQSLEGRyrQELKDLLDQHLEERSQWEFEKDEL 896
Cdd:PRK04863  574 -VSEARERRMALRQQLEqlqariQRLAARAPAWLAAQDALARLREQSGEEFEDS--QDVTEYMQQLLERERELTVERDEL 650
                         490
                  ....*....|....*...
gi 672056299  897 TQECTEAQEQLEEVLQRE 914
Cdd:PRK04863  651 AARKQALDEEIERLSQPG 668
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
1532-1811 3.28e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 52.24  E-value: 3.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1532 RKVELL---RYES---EKLQEENSIlrnEITTLNEEdsISNLKLEELNGSQEELWQKIETIEQ-------EKASIQKM-V 1597
Cdd:PRK05771    7 KKVLIVtlkSYKDevlEALHELGVV---HIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSylpklnpLREEKKKVsV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1598 EKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQK---EDP-------------GTCTSEKWE--- 1658
Cdd:PRK05771   82 KSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGnfdLDLslllgfkyvsvfvGTVPEDKLEelk 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1659 QENESLKEELDRYKVQTSTLVSSLEAELSEvklqthivEQENLLLKDELERLKqlhrCPDLSDFQQKMCSILSYNENLLK 1738
Cdd:PRK05771  162 LESDVENVEYISTDKGYVYVVVVVLKELSD--------EVEEELKKLGFERLE----LEEEGTPSELIREIKEELEEIEK 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1739 EKEVLSEELKSCADKLAEssllehRIATIKEEREAwEEQSQDLKSQLALSQ-----------EKVQNLEDILKNVNLQMA 1807
Cdd:PRK05771  230 ERESLLEELKELAKKYLE------ELLALYEYLEI-ELERAEALSKFLKTDktfaiegwvpeDRVKKLKELIDKATGGSA 302

                  ....
gi 672056299 1808 QIES 1811
Cdd:PRK05771  303 YVEF 306
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
741-1060 3.32e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.43  E-value: 3.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   741 EKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAaawTEEKARSLTR--DLEQSHQEQLLSLMEKHALEKEELRke 818
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQE---KEEKAREVERrrKLEEAEKARQAEMDRQAAIYAEQER-- 341
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   819 LSEYHQRELQEGREEMETECNRRVSQIEAQFQADCEKVTERCEQTLQSLEGRYRQELKDLLDQHLEER------SQWEFE 892
Cdd:pfam17380  342 MAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEerqrkiQQQKVE 421
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   893 KDELTQECTEAQEQLEEVLQREKATALARSQEQEtlekthkerlailsMEREQLLQDLKDLQNTSERQHSLLSDQMLELK 972
Cdd:pfam17380  422 MEQIRAEQEEARQREVRRLEEERAREMERVRLEE--------------QERQQQVERLRQQEEERKRKKLELEKEKRDRK 487
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   973 RSQERELREPEHVLCQTgvSEQLGSQQLARLQVEHEQERREMAgkIAALESAHRVSCERADQEKAEmsaEIRRLQSTVKD 1052
Cdd:pfam17380  488 RAEEQRRKILEKELEER--KQAMIEEERKRKLLEKEMEERQKA--IYEEERRREAEEERRKQQEME---ERRRIQEQMRK 560

                   ....*...
gi 672056299  1053 LQQATSLL 1060
Cdd:pfam17380  561 ATEERSRL 568
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1204-1712 4.27e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.99  E-value: 4.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1204 SELENSEDTRTESWDLKSQIIQLQEQLTVLRADCDRASERKRDLLFDISVLKKKLKMLE----RLPEAsSKYKVLYEDAA 1279
Cdd:PRK03918  221 EELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEekvkELKEL-KEKAEEYIKLS 299
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1280 RENACLQEELRLMEMRYADSLDSNKELTAEVYRLQDEMKKMEEVTGTFLSLENSYDEVKlENEKLSALVLRLQGKMEEVL 1359
Cdd:PRK03918  300 EFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLK 378
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1360 ERAAlqgdsyslwegpseNLEVTSDEKMLELHQTEEEctpEVMSRhhiIEECRQETRCCEQGSTQLLAGIKAHEIAwfrr 1439
Cdd:PRK03918  379 KRLT--------------GLTPEKLEKELEELEKAKE---EIEEE---ISKITARIGELKKEIKELKKAIEELKKA---- 434
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1440 kiethQEKPSVQNRVILEESAALLgLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKQKDAPSQGEEEEELKAV 1519
Cdd:PRK03918  435 -----KGKCPVCGRELTEEHRKEL-LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKEL 508
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1520 MHDLQ-ITCGEMQRKVEllryESEKLQEENSILRNEITTLNEEDSisnlKLEELNGSQEELWQKIETIEQEKASIQKMVE 1598
Cdd:PRK03918  509 EEKLKkYNLEELEKKAE----EYEKLKEKLIKLKGEIKSLKKELE----KLEELKKKLAELEKKLDELEEELAELLKELE 580
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1599 KLK-KQVSDLKLKNQQLDSENKE-LSQKNS-QNKEELKTLNQRLAEMLCQKEDPGTCTSEKWEQENESLKEELDRYKVQT 1675
Cdd:PRK03918  581 ELGfESVEELEERLKELEPFYNEyLELKDAeKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE 660
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 672056299 1676 -----------STLVSSLEAELSEVKLQTHIVEQENLLLKDELERLKQ 1712
Cdd:PRK03918  661 yeelreeylelSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
559-1012 4.32e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 4.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  559 QEERLAQMRNEYEQqCRLLQDQVDELQSELEEYQAQGRVLRLPcQNALSEELDGHGDGIEQDQepgsgecnplnmsIEAE 638
Cdd:COG4717    76 LEEELKEAEEKEEE-YAELQEELEELEEELEELEAELEELREE-LEKLEKLLQLLPLYQELEA-------------LEAE 140
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  639 LVIEQLKEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEIADLQGQAAVLKE 718
Cdd:COG4717   141 LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQE 220
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  719 AHHKASCRHEEEKKQLQMVFDEEK-TQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAA---WTEEKARSLTRDLE 794
Cdd:COG4717   221 ELEELEEELEQLENELEAAALEERlKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLgllALLFLLLAREKASL 300
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  795 QSHQEQLLSLMEKHALEKEELRKELSEYH-QRELQEGREEMETECNRRVSQIEAQFQADCEKVT-ERCEQTLQSLEGRYR 872
Cdd:COG4717   301 GKEAEELQALPALEELEEEELEELLAALGlPPDLSPEELLELLDRIEELQELLREAEELEEELQlEELEQEIAALLAEAG 380
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  873 QELKDLLDQHLEERSQWEfekdELTQECTEAQEQLEEvlQREKATALARSQEQETLEKTHKERLAILSMEREQLLQDLKD 952
Cdd:COG4717   381 VEDEEELRAALEQAEEYQ----ELKEELEELEEQLEE--LLGELEELLEALDEEELEEELEELEEELEELEEELEELREE 454
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  953 LQNTSERQHSLLSDQMLELKRSQERELREPEHVLCQTGVSEQLGSQQLARLQVEHEQERR 1012
Cdd:COG4717   455 LAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1473-1697 5.95e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 5.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1473 EATIAELELEKQKLQELTRNLRERVTTLAKQKDA------PSQGEEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQE 1546
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEE 322
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1547 ENSILRNEITTLNEEDSISNLKLEELNGSQ--------------EELWQKIETIE-------QEKASIQKMVEKLKKQVS 1605
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEELEREIEEERKRRdklteeyaelkeelEDLRAELEEVDkefaetrDELKDYREKLEKLKREIN 402
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1606 DLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDPGTCTSEKwEQENESLKEELDRYKVQ---TSTLVSSL 1682
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ-EWKLEQLAADLSKYEQElydLKEEYDRV 481
                          250
                   ....*....|....*
gi 672056299  1683 EAELSEVKLQTHIVE 1697
Cdd:TIGR02169  482 EKELSKLQRELAEAE 496
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1457-1827 5.97e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.31  E-value: 5.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1457 EESAALLGLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKQKDAPSQGEEEEELKAVMHDLQITCGEMQRKVEL 1536
Cdd:COG4717    78 EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEE 157
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1537 ---LRYESEKLQEENSILRNEITTLNEEDSISNLK-LEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLklknq 1612
Cdd:COG4717   158 lreLEEELEELEAELAELQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL----- 232
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1613 QLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDPGTCTS-------------------EKWEQENESLKEELDRYKV 1673
Cdd:COG4717   233 ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTiagvlflvlgllallflllAREKASLGKEAEELQALPA 312
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1674 QTSTLVSSLEAELSEVKLQTHIVEQENLLLKDELERLKQLHRcpDLSDFQQKM--CSILSYNENLLKEKEVLSEE----- 1746
Cdd:COG4717   313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR--EAEELEEELqlEELEQEIAALLAEAGVEDEEelraa 390
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1747 ---LKSCADKLAESSLLEHRIATIKEER---------EAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESD-- 1812
Cdd:COG4717   391 leqAEEYQELKEELEELEEQLEELLGELeellealdeEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDge 470
                         410
                  ....*....|....*
gi 672056299 1813 LQVTRQEKEALKQEV 1827
Cdd:COG4717   471 LAELLQELEELKAEL 485
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
1532-1982 7.09e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.17  E-value: 7.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1532 RKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDlklKN 1611
Cdd:TIGR04523  197 LKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSE---KQ 273
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1612 QQLDSENKELSQKNSQNKE---ELKTLNQ--------RLAEMLCQKEDPGTCTSEKWEQENE---SLKEELDRYKVQTST 1677
Cdd:TIGR04523  274 KELEQNNKKIKELEKQLNQlksEISDLNNqkeqdwnkELKSELKNQEKKLEEIQNQISQNNKiisQLNEQISQLKKELTN 353
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1678 LVS---SLEAELSEVKLQTHIVEQENLLLKDELERLKQlhrcpDLSDFQQKmcsiLSYNENLLKEKEVLSEELKScadkl 1754
Cdd:TIGR04523  354 SESensEKQRELEEKQNEIEKLKKENQSYKQEIKNLES-----QINDLESK----IQNQEKLNQQKDEQIKKLQQ----- 419
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1755 aESSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQL 1834
Cdd:TIGR04523  420 -EKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKEL 498
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1835 QNAIDKdwVSETATHLSGLQGQQKRLSwNKLDHLMSEEPELLcQESKRLQTVVQNTQADLTHSREKIRQLESNlLPTKHQ 1914
Cdd:TIGR04523  499 KKLNEE--KKELEEKVKDLTKKISSLK-EKIEKLESEKKEKE-SKISDLEDELNKDDFELKKENLEKEIDEKN-KEIEEL 573
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672056299  1915 KQLNQSCTVKPIEQEKLALKRECEQSrKERSPTSRKVSQMSSLERELETIHLENEGLKKKQVRLDEKL 1982
Cdd:TIGR04523  574 KQTQKSLKKKQEEKQELIDQKEKEKK-DLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKK 640
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
461-939 7.45e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 7.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  461 AALKNELRQEREQILQQVGKQRVELEQEIEKAKTEenyiRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLEN 540
Cdd:COG4717    45 AMLLERLEKEADELFKPQGRKPELNLKELKELEEE----LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  541 VlaekfgdldpssaEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRlpcqnALSEELDGHGDGIEQD 620
Cdd:COG4717   121 L-------------EKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELE-----ELEAELAELQEELEEL 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  621 QEPGSGEC-NPLNMSIEAELVIEQLKEQHHRDLCHLRLELEDKvrhyEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQI 699
Cdd:COG4717   183 LEQLSLATeEELQDLAEELEELQQRLAELEEELEEAQEELEEL----EEELEQLENELEAAALEERLKEARLLLLIAAAL 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  700 SELQSEIADLQGQA----------------AVLKEAHHKASCRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQ 763
Cdd:COG4717   259 LALLGLGGSLLSLIltiagvlflvlgllalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEE 338
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  764 AEESFRQEREGLAQAAAWTEEKARsltRDLEQSHQEQLLSLMEKHALEKEELRKELSEYhqRELQEGREEMEtECNRRVS 843
Cdd:COG4717   339 LLELLDRIEELQELLREAEELEEE---LQLEELEQEIAALLAEAGVEDEEELRAALEQA--EEYQELKEELE-ELEEQLE 412
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  844 QIEAQFQADCEKVT-ERCEQTLQSLEGRyRQELKDLLDQHLEERSQWEFEK---------DELTQECTEAQEQLEEVLQR 913
Cdd:COG4717   413 ELLGELEELLEALDeEELEEELEELEEE-LEELEEELEELREELAELEAELeqleedgelAELLQELEELKAELRELAEE 491
                         490       500
                  ....*....|....*....|....*.
gi 672056299  914 EKATALARSQEQETLEKTHKERLAIL 939
Cdd:COG4717   492 WAALKLALELLEEAREEYREERLPPV 517
PTZ00121 PTZ00121
MAEBL; Provisional
1480-1802 8.19e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 8.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1480 ELEKQKLQELTRNLRERVTTLAKQkdapSQGEEEEELKAvmhdlqitcgEMQRKVELLRYESEKLQEENSILRNEITTLN 1559
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAEE----AKKAEEAKIKA----------EELKKAEEEKKKVEQLKKKEAEEKKKAEELK 1653
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1560 EEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKlKNQQLDSENKELSQKNSQNKEElKTLNQRL 1639
Cdd:PTZ00121 1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK-KAEELKKKEAEEKKKAEELKKA-EEENKIK 1731
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1640 AEMLCQKEDpgtctsEKWEQENESLKEELDRYKVQtsTLVSSLEAELSEVKLQTHIVEQENLLLKDELERLKQLHRCPDL 1719
Cdd:PTZ00121 1732 AEEAKKEAE------EDKKKAEEAKKDEEEKKKIA--HLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDI 1803
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1720 SDFQQKMcsILSYNENLL---KEKEVLSEELKSCADklAESSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKvQNLE 1796
Cdd:PTZ00121 1804 FDNFANI--IEGGKEGNLvinDSKEMEDSAIKEVAD--SKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEK-DLKE 1878

                  ....*.
gi 672056299 1797 DILKNV 1802
Cdd:PTZ00121 1879 DDEEEI 1884
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
391-876 9.38e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 9.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  391 ALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLR-----KLDEEYKERIAALKN 465
Cdd:PRK02224  238 EADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDllaeaGLDDADAEAVEARRE 317
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  466 ELRQEREQILQQVGKQRV---ELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLENvL 542
Cdd:PRK02224  318 ELEDRDEELRDRLEECRVaaqAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEE-L 396
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  543 AEKFGDL--DPSSAEFFLQE-----ERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQgrvlrlPCQNALSEEldGHGD 615
Cdd:PRK02224  397 RERFGDApvDLGNAEDFLEElreerDELREREAELEATLRTARERVEEAEALLEAGKCP------ECGQPVEGS--PHVE 468
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  616 GIEQDQEPGSgecnplnmSIEAELviEQLKEQhhRDLCHLRLELEDKVRHYEKQLDHTRvacEKEQVAMKQKYEQGMRTL 695
Cdd:PRK02224  469 TIEEDRERVE--------ELEAEL--EDLEEE--VEEVEERLERAEDLVEAEDRIERLE---ERREDLEELIAERRETIE 533
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  696 EK--QISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQmVFDEEKTQLQEEL----RLEHEQELKARLQQAEESFR 769
Cdd:PRK02224  534 EKreRAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVA-ELNSKLAELKERIesleRIRTLLAAIADAEDEIERLR 612
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  770 QEREGLAQAAAWTEEK---ARSLTRDLEQSHQEQLLSLMEKHALEKEELRKELSEYhQRELQEGREEMETECNRRVSQIE 846
Cdd:PRK02224  613 EKREALAELNDERRERlaeKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEK-LDELREERDDLQAEIGAVENELE 691
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 672056299  847 --AQFQADCEKVTERCE---------QTLQSLEGRYRQELK 876
Cdd:PRK02224  692 elEELRERREALENRVEalealydeaEELESMYGDLRAELR 732
PTZ00121 PTZ00121
MAEBL; Provisional
407-1052 9.53e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 9.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  407 DQVVREKEKLRSDLDKAEKLKSLMASEV--DDHHAAIERRNEYNLRK-------LDEEYKERIAALKNELRQEREQILQQ 477
Cdd:PTZ00121 1039 DDVLKEKDIIDEDIDGNHEGKAEAKAHVgqDEGLKPSYKDFDFDAKEdnradeaTEEAFGKAEEAKKTETGKAEEARKAE 1118
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  478 VGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLEnvlAEKFGDLDPSSAEFF 557
Cdd:PTZ00121 1119 EAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEA---ARKAEEVRKAEELRK 1195
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  558 LQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVlRLPCQNALSEELDGHGDGIEQDQEPGSGECNPLNMSIEA 637
Cdd:PTZ00121 1196 AEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEA-KKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  638 ElviEQLKEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVA--MKQKYEQGMRTLEKqiSELQSEIADLQGQAAV 715
Cdd:PTZ00121 1275 E---EARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEAKKKADA--AKKKAEEAKKAAEAAK 1349
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  716 LKEAHHKASCRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKA-RLQQAEESFRQEREGLAQAAAwTEEKARSLTRDLE 794
Cdd:PTZ00121 1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdEAKKKAEEDKKKADELKKAAA-AKKKADEAKKKAE 1428
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  795 QSHQEQLLSLMEKHALEKEELRKELSEYHQRELQEGREEMETECNRRVSQIEAQFQADcEKVTERCEQTLQSLEGRYRQE 874
Cdd:PTZ00121 1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKAD-EAKKKAEEAKKKADEAKKAAE 1507
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  875 LK---DLLDQHLEERSQWEFEKDELTQECTEAQ--EQLEEVLQREKATALARSQEQETLEKTHKERlailsMEREQLLQD 949
Cdd:PTZ00121 1508 AKkkaDEAKKAEEAKKADEAKKAEEAKKADEAKkaEEKKKADELKKAEELKKAEEKKKAEEAKKAE-----EDKNMALRK 1582
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  950 LKDLQNTSERQHSLLSDQMLELKRSQERELREPEHVLCQtgvSEQLGSQQLARLQVEHEQERREMAGKIA-ALESAHRVS 1028
Cdd:PTZ00121 1583 AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK---AEELKKAEEEKKKVEQLKKKEAEEKKKAeELKKAEEEN 1659
                         650       660
                  ....*....|....*....|....
gi 672056299 1029 CERADQEKAEMSAEIRRLQSTVKD 1052
Cdd:PTZ00121 1660 KIKAAEEAKKAEEDKKKAEEAKKA 1683
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
377-1060 1.00e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   377 ENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERrneynlrkldeey 456
Cdd:TIGR02169  365 ELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAG------------- 431
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   457 kerIAALKNELRQEREQILQQVGKQRVELEQEIEKAKTEENYIRDRlalslkennrlenellenAEKLAEYENLTSKLQR 536
Cdd:TIGR02169  432 ---IEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL------------------KEEYDRVEKELSKLQR 490
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   537 SLENVLAEKfGDLDPSSAEFFLQEERLaqmrneyEQQCRLLQDQVDELQSELEEYQAQGRVL---RLpcQNALSEELDGH 613
Cdd:TIGR02169  491 ELAEAEAQA-RASEERVRGGRAVEEVL-------KASIQGVHGTVAQLGSVGERYATAIEVAagnRL--NNVVVEDDAVA 560
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   614 GDGIE--QDQEPGSGECNPLNMSIEAELVIEQLKEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQG 691
Cdd:TIGR02169  561 KEAIEllKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYR 640
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   692 MRTLEkqiselqSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQMVFDeektqlqeelRLEHEQELKARLQQAEESFRQE 771
Cdd:TIGR02169  641 MVTLE-------GELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRE----------RLEGLKRELSSLQSELRRIENR 703
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   772 REGLAQAAAWTEEKARSLTRDLEQshqeqllsLMEKHALEKEELrkELSEYHQRELQEGREEMETECNRRVSQIEAQfQA 851
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQ--------LEQEEEKLKERL--EELEEDLSSLEQEIENVKSELKELEARIEEL-EE 772
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   852 DCEKVTERCEQTLQSLEGRYRQELKDLLDQHLEERSQWEFEKDELTQEcTEAQEQLEEVLQREKATALARSQEQETLEKT 931
Cdd:TIGR02169  773 DLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQK-LNRLTLEKEYLEKEIQELQEQRIDLKEQIKS 851
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   932 HKERLAILSMEREQLLQDLKDLQNtSERQhslLSDQMLELKRsqERELREPEHVLCQTGVSEQLGSQQLARLQVEHEQER 1011
Cdd:TIGR02169  852 IEKEIENLNGKKEELEEELEELEA-ALRD---LESRLGDLKK--ERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 672056299  1012 REmagkIAALESAHRVSCERADQEKAEMSAEIRRLQSTVKDLQQATSLL 1060
Cdd:TIGR02169  926 LE----ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
558-981 1.16e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.72  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  558 LQEERLAQMRNEYEQQcrllqdqvDELQSELE-EYQAQGRVLRLpCQNALseeldGHGDGIEQDQEpgsgECNPLNMSI- 635
Cdd:COG3096   303 EEQYRLVEMARELEEL--------SARESDLEqDYQAASDHLNL-VQTAL-----RQQEKIERYQE----DLEELTERLe 364
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  636 EAELVIEQLKEQHHRdlCHLRLEL-EDKVRHYEKQLDHTRVACEKEQVAMKQkYEQGMRTLEKqiSELQSEIADLQGQAA 714
Cdd:COG3096   365 EQEEVVEEAAEQLAE--AEARLEAaEEEVDSLKSQLADYQQALDVQQTRAIQ-YQQAVQALEK--ARALCGLPDLTPENA 439
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  715 VLKEAHHKAscrheEEKKQLQMVFD-EEKTQLQEELRLEHEQELKARLQQAEESFRqereglaqAAAWteEKARSLTRDL 793
Cdd:COG3096   440 EDYLAAFRA-----KEQQATEEVLElEQKLSVADAARRQFEKAYELVCKIAGEVER--------SQAW--QTARELLRRY 504
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  794 -EQSHQEQLLslmekhalekEELRKELSEYHQRELQegreemetecnrrvsQIEAQFQAdcekvTERCEQTLQSLEGRyr 872
Cdd:COG3096   505 rSQQALAQRL----------QQLRAQLAELEQRLRQ---------------QQNAERLL-----EEFCQRIGQQLDAA-- 552
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  873 qelkDLLDQHLEErsqWEFEKDELTQECTEAQEQLEEVLQREKATAlARSQEQETLE---KTHKERLAILSMEREQLLQD 949
Cdd:COG3096   553 ----EELEELLAE---LEAQLEELEEQAAEAVEQRSELRQQLEQLR-ARIKELAARApawLAAQDALERLREQSGEALAD 624
                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 672056299  950 LKDLQNT------SERQHSLLSDQMLELKRSQERELRE 981
Cdd:COG3096   625 SQEVTAAmqqlleREREATVERDELAARKQALESQIER 662
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
878-1715 1.98e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.97  E-value: 1.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   878 LLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKTHKERLAILSMEREQLLQDLKDL--QN 955
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlqEL 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   956 TSERQHSLLSDQMLELKRSQERELREPEHVLCQTgvSEQLGSQQLARLQVEHEQERREMAGKIAALESAHRVScERADQE 1035
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK--EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKL-KESEKE 322
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1036 KAEMSAEIRRLQSTVKDLQQATSLLVLQGGCRATAGEEAEGNGALSLLQQGEQLL------EENGDVLISLQKAHERAVK 1109
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAkkklesERLSSAAKLKEEELELKSE 402
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1110 ENAKMATEISRLQQRLKKLEPGSAISSCLEERMTEISGSSREHAEPV-MKRGTATKHFLSDPGDHEAQGLGSTGTSSVQR 1188
Cdd:pfam02463  403 EEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEkEELEKQELKLLKDELELKKSEDLLKETQLVKL 482
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1189 QECRTEESEASLECFSELENSEDTRTESWDLKSQIIQLQEQLTVLRADCDRASERKRDLLFDISVLKKKLKMLERLPEAS 1268
Cdd:pfam02463  483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1269 SKYKVLYEDAARENAcLQEELRLMEMRYADSLDSNKELTAEVYRLQDEMKKMEEVTGTFLSLENSYDEVKLENEKLSALV 1348
Cdd:pfam02463  563 RQKLVRALTELPLGA-RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1349 LRLQGKMEEVLERAALQGDSYSLWEGPSENLEVTSDEKMLELHQTEEECTPEVMSRHHIIEECRQETRCCEQGSTQLLAG 1428
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1429 IKAHEIAWFRRKIETHQEKpsvQNRVILEESAALLGLQGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKQKDAPS 1508
Cdd:pfam02463  722 LLADRVQEAQDKINEELKL---LKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1509 QGEEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSIsnlKLEELNGSQEELWQKIETIEQ 1588
Cdd:pfam02463  799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE---ELERLEEEITKEELLQELLLK 875
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1589 EKASIQKMVEKLKKQVsdLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDPGTCTSEKWEQENE-----S 1663
Cdd:pfam02463  876 EEELEEQKLKDELESK--EEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEkekeeN 953
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 672056299  1664 LKEELDRYKVQTSTLVSSLEAELSEVKLQTHIVEQENLLLKDELERLKQLHR 1715
Cdd:pfam02463  954 NKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKK 1005
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
337-535 3.11e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.24  E-value: 3.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  337 VERILDTWQEEGIE-NSQEILKALDFsLDGNINLTELTL-ALENELLVTKNgihQAALASFKAEIRHLLERVDQVVREKE 414
Cdd:COG3206   154 ANALAEAYLEQNLElRREEARKALEF-LEEQLPELRKELeEAEAALEEFRQ---KNGLVDLSEEAKLLLQQLSELESQLA 229
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  415 KLRSDLDKAE----------KLKSLMASEVDDHHAAIERRNEYN-----LRKLDEEYKE---RIAALKNELRQEREQILQ 476
Cdd:COG3206   230 EARAELAEAEarlaalraqlGSGPDALPELLQSPVIQQLRAQLAeleaeLAELSARYTPnhpDVIALRAQIAALRAQLQQ 309
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 672056299  477 QVGKQRVELEQEIEKAKTEENYIRDRLAlslkennRLENELLENAEKLAEYENLTSKLQ 535
Cdd:COG3206   310 EAQRILASLEAELEALQAREASLQAQLA-------QLEARLAELPELEAELRRLEREVE 361
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
480-833 3.14e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.28  E-value: 3.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   480 KQRVELEQEIEKakTEENYirDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLENVLAEKFGDLDPSSAEFFLQ 559
Cdd:TIGR02168  172 ERRKETERKLER--TRENL--DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEE 247
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   560 EERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQgrvlrlpcQNALSEELDGHGDGIEqdqepgsgecnplnmsiEAEL 639
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEE--------IEELQKELYALANEIS-----------------RLEQ 302
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   640 VIEQLKEQHHRdlchlrleLEDKVRHYEKQLDHTRvacekeqvAMKQKYEQGMRTLEKQISELQSEIADLQGQAAVLKEA 719
Cdd:TIGR02168  303 QKQILRERLAN--------LERQLEELEAQLEELE--------SKLDELAEELAELEEKLEELKEELESLEAELEELEAE 366
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   720 HHKASCRHEEEKKQLQM----VFDEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEEKARSLTRDLEQ 795
Cdd:TIGR02168  367 LEELESRLEELEEQLETlrskVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELE 446
                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 672056299   796 SHQEQLLSLMEKHALEKEELRKELSEYHQRELQEGREE 833
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAEREL 484
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
553-1050 3.46e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 3.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   553 SAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNALSEELDGHGDGIEQDQEPGSGECNPLN 632
Cdd:TIGR00618  241 SHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKM 320
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   633 MSIEAELVIEQLKEQHHRDLCHLRLELEDKVR-HYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEIADLQG 711
Cdd:TIGR00618  321 RSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSqEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCK 400
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   712 QAAVLKEAHHKASCRHEEEKKQLQMVFDEEKTQLQEELRLEHE--------QELKARLQQAEESFRQEREGLAQaaawtE 783
Cdd:TIGR00618  401 ELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCaaaitctaQCEKLEKIHLQESAQSLKEREQQ-----L 475
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   784 EKARSLTRDLEQSHQEQLLSLMEkHALEKEELRKELSEYHQRELQEGREEMETECNRRVSQIEAQFQADCEKVTERCEQT 863
Cdd:TIGR00618  476 QTKEQIHLQETRKKAVVLARLLE-LQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSE 554
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   864 LQSLEgRYRQELKDLLDQHLEERSQWEFEKDE---LTQECTEAQEQLEEVLQREKATALA-RSQEQETLEKTHKERLAIL 939
Cdd:TIGR00618  555 RKQRA-SLKEQMQEIQQSFSILTQCDNRSKEDipnLQNITVRLQDLTEKLSEAEDMLACEqHALLRKLQPEQDLQDVRLH 633
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   940 SMEREQLLQDLK--------DLQNTSERQHSLLSDQM-LELKRSQERELREPEHVLCQ-TGVSEQLG-SQQLARLQVEHE 1008
Cdd:TIGR00618  634 LQQCSQELALKLtalhalqlTLTQERVREHALSIRVLpKELLASRQLALQKMQSEKEQlTYWKEMLAqCQTLLRELETHI 713
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 672056299  1009 QERREMAGKIAALESAHRVSCERADQEKAEMSAEIRRLQSTV 1050
Cdd:TIGR00618  714 EEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTV 755
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
345-1013 4.19e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.81  E-value: 4.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   345 QEEGIENSQEILKALDFSLDGNINLTELTLALENELLVTKNGIHQAALAsfKAEIRHLLERVDQVVREKEKLRSDLDKAE 424
Cdd:pfam02463  276 EEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK--KAEKELKKEKEEIEELEKELKELEIKREA 353
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   425 KLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRQEREQILQQVGKQRVELEQEIEKAKTEENYIRDRLA 504
Cdd:pfam02463  354 EEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILE 433
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   505 LSLKENNRLENELLENAEKLAEYENLTSKLQRSLENV-----------------LAEKFGDLDPSSAEFFLQEERLAQMR 567
Cdd:pfam02463  434 EEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSedllketqlvklqeqleLLLSRQKLEERSQKESKARSGLKVLL 513
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   568 NEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNALSEELdghGDGIEQDQEPGSGECNPLNMSIEAELVIEQLKEQ 647
Cdd:pfam02463  514 ALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSAT---ADEVEERQKLVRALTELPLGARKLRLLIPKLKLP 590
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   648 HHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRH 727
Cdd:pfam02463  591 LKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSE 670
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   728 EEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEE----SFRQEREGLAQAAAWTEEKARSLTRDLEQSHQEQLLS 803
Cdd:pfam02463  671 LTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKeelkKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEE 750
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   804 LMEKHALEKEELRKELSEYHQRELQEGREEMETECNRRVSQIEAQFQADCEKVTERcEQTLQSLEGRYRQELKDLLDQHL 883
Cdd:pfam02463  751 EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL-EEELKEEAELLEEEQLLIEQEEK 829
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   884 EERSQWEFEKDELtQECTEAQEQLEEVLQREKATALARSQEQETLEKTHK---ERLAILSMEREQLLQDLKDLQNTSERQ 960
Cdd:pfam02463  830 IKEEELEELALEL-KEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEleeQKLKDELESKEEKEKEEKKELEEESQK 908
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 672056299   961 HSLLSDQMLELKRSQERELREPEHVLCQTGVSEQLGSQQLARLQVEHEQERRE 1013
Cdd:pfam02463  909 LNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER 961
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1760-1982 4.55e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 4.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1760 LEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQLQNAID 1839
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1840 KDWVSETATHLSGLqgqqkrlswnkldhLMSEEPELLCQESKRLQTVVQNTQADLTHSREKIRQLEsnllpTKHQKQLNQ 1919
Cdd:COG4942   112 ALYRLGRQPPLALL--------------LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA-----ALRAELEAE 172
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672056299 1920 SCTVKPIEQEKLALKRECEQSRKERSptsrkvSQMSSLERELETIHLENEGLKKKQVRLDEKL 1982
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQ------KLLARLEKELAELAAELAELQQEAEELEALI 229
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
1444-1974 5.14e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.56  E-value: 5.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1444 HQEKPSVQNRVILEesAALLGLQGTHLQHEATIAELELEKQKLQELTR--NLRERVTTLAKQKDAPSQGE------EEEE 1515
Cdd:pfam05483  103 QKENKLQENRKIIE--AQRKAIQELQFENEKVSLKLEEEIQENKDLIKenNATRHLCNLLKETCARSAEKtkkyeyEREE 180
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1516 LKAVMHDLQITCGEMqrkveLLRYESEKLQEENSILRNEITTLNEEDSISNLKLE---ELNGSQEE---LWQKIETIEQE 1589
Cdd:pfam05483  181 TRQVYMDLNNNIEKM-----ILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEykkEINDKEKQvslLLIQITEKENK 255
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1590 KASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKE------DPGTCTSEKWEQENES 1663
Cdd:pfam05483  256 MKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKaleedlQIATKTICQLTEEKEA 335
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1664 LKEELDRYKVQTSTLVSSLEAELSEVKLqthiveqenlLLKDELERLKQLHRCPDLSDFQ-QKMCSILSYNENLLKEKEV 1742
Cdd:pfam05483  336 QMEELNKAKAAHSFVVTEFEATTCSLEE----------LLRTEQQRLEKNEDQLKIITMElQKKSSELEEMTKFKNNKEV 405
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1743 LSEELKSCadkLAESSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQ--VTRQEK 1820
Cdd:pfam05483  406 ELEELKKI---LAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEdlKTELEK 482
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1821 EALKQEVMSLHLQLQNAIDKDWVSETATHLSGLQGQQKRLSWNKldhlmsEEPELLCQESKRLQTVVQNTQADLTHSREK 1900
Cdd:pfam05483  483 EKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCK------KQEERMLKQIENLEEKEMNLRDELESVREE 556
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672056299  1901 IRQLESNL---LPTKHQKQLNQSCTVKPIEQEKLALKRECEQSRKersptsrkvsQMSSLERELETIHLENEGLKKK 1974
Cdd:pfam05483  557 FIQKGDEVkckLDKSEENARSIEYEVLKKEKQMKILENKCNNLKK----------QIENKNKNIEELHQENKALKKK 623
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
426-1126 6.04e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 6.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   426 LKSLMASEVDDHHAAIERRNEYN--LRKLDEEYKERIAALKNEL-------RQEREQILQQVGKQRVELEQEIEKAKTEE 496
Cdd:pfam12128  267 YKSDETLIASRQEERQETSAELNqlLRTLDDQWKEKRDELNGELsaadaavAKDRSELEALEDQHGAFLDADIETAAADQ 346
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   497 NYIrDRLALSLKENNRLENELLENAEKL-AEYENLTSKLQRSLENVLAEKFGDLDPSSAEFFLQeerLAQMRNEYEQQCR 575
Cdd:pfam12128  347 EQL-PSWQSELENLEERLKALTGKHQDVtAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQ---LAVAEDDLQALES 422
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   576 LLQDQVDELQSELEEyQAQGRVLRLpcqnalsEELDGHGDGIEQDQEpgsgecNPLNMSIEAELVIEQLKEQHHRDLCHL 655
Cdd:pfam12128  423 ELREQLEAGKLEFNE-EEYRLKSRL-------GELKLRLNQATATPE------LLLQLENFDERIERAREEQEAANAEVE 488
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   656 RLELEDKV--RHYEKQLDHTRVaCEKEQVAMKQKYEQGMRTLEKQISELqseIADLQGQAAVLKEAHHKASCRHEEEKKQ 733
Cdd:pfam12128  489 RLQSELRQarKRRDQASEALRQ-ASRRLEERQSALDELELQLFPQAGTL---LHFLRKEAPDWEQSIGKVISPELLHRTD 564
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   734 LQMVFDEEKT--------------QLQEELRLEHEQELKARLQQAEESFRQEREGLAQAaawtEEKARSLTRDLEQSHQE 799
Cdd:pfam12128  565 LDPEVWDGSVggelnlygvkldlkRIDVPEWAASEEELRERLDKAEEALQSAREKQAAA----EEQLVQANGELEKASRE 640
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   800 QLLSlmeKHALEKEELR-KELSEYHQRE---LQEGREEMETECNRRVSQIEAQfqadcekvterceqtLQSLEGRYRQEL 875
Cdd:pfam12128  641 ETFA---RTALKNARLDlRRLFDEKQSEkdkKNKALAERKDSANERLNSLEAQ---------------LKQLDKKHQAWL 702
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   876 KDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKTH-------KERLAILSMEREQLLQ 948
Cdd:pfam12128  703 EEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDlaslgvdPDVIAKLKREIRTLER 782
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   949 DLKDLQntSERQHSLLSDQMLELKRSQERELREPEHVLCQTGVSEQlgSQQLARLQVEHEQERREMAGKIAALESAHrvs 1028
Cdd:pfam12128  783 KIERIA--VRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISEL--QQQLARLIADTKLRRAKLEMERKASEKQQ--- 855
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1029 cERADQEKAEMSAEIRRLqSTVKDLQQAtsllvlqggcratagEEAEGNGALSlLQQGEQLLEENGDVLISLQKAHERAV 1108
Cdd:pfam12128  856 -VRLSENLRGLRCEMSKL-ATLKEDANS---------------EQAQGSIGER-LAQLEDLKLKRDYLSESVKKYVEHFK 917
                          730
                   ....*....|....*....
gi 672056299  1109 KE-NAKMATEISRLQQRLK 1126
Cdd:pfam12128  918 NViADHSGSGLAETWESLR 936
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1476-1984 6.14e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 6.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1476 IAELELEKQKLQELTRNLRERVTTLAKQ-KDAPSQGEEEEELKAVMhDLQITCGEMQRKVELLRYESEKLQEENSILRNE 1554
Cdd:PRK03918  247 LESLEGSKRKLEEKIRELEERIEELKKEiEELEEKVKELKELKEKA-EEYIKLSEFYEEYLDELREIEKRLSRLEEEING 325
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1555 ITTLNEEDSISNLKLEELNGSQEELWQKIETIE------QEKASIQKMVEKLKKQVSDLKLknQQLDSENKELSQKNSQN 1628
Cdd:PRK03918  326 IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTP--EKLEKELEELEKAKEEI 403
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1629 KEELKTLNQRLAEMLCQKED-----------PGTCTSEKWEQENESLKEELDRYKVQtstlVSSLEAELSEVKLQTHIVE 1697
Cdd:PRK03918  404 EEEISKITARIGELKKEIKElkkaieelkkaKGKCPVCGRELTEEHRKELLEEYTAE----LKRIEKELKEIEEKERKLR 479
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1698 QENLLLKDELERLKQLHRCPDLSDFQQKMCSILS-YNENLLKEKEVLSEELKSCADKLaessllEHRIATIKEEREAWEE 1776
Cdd:PRK03918  480 KELRELEKVLKKESELIKLKELAEQLKELEEKLKkYNLEELEKKAEEYEKLKEKLIKL------KGEIKSLKKELEKLEE 553
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1777 qsqdLKSQLALSQEKVQNLEDILKNVNLQMAQI----ESDLQVTRQEKEALKQEVMSLhlqlqnaidKDWVSEtathlsg 1852
Cdd:PRK03918  554 ----LKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLEL---------KDAEKE------- 613
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1853 LQGQQKRLSWNKLDHLMSEEPellcqeskrlqtvVQNTQADLTHSREKIRQLESNLLPTKHQKqlnqsctvkpIEQEKLA 1932
Cdd:PRK03918  614 LEREEKELKKLEEELDKAFEE-------------LAETEKRLEELRKELEELEKKYSEEEYEE----------LREEYLE 670
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 672056299 1933 LKREceqsrkerspTSRKVSQMSSLERELETIHLENEGLKKKQVRLDEKLME 1984
Cdd:PRK03918  671 LSRE----------LAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE 712
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
388-913 1.19e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  388 HQAALASFKAEIRHLLERVDQVvrEKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYN--LRKLDEEYKERIAALKn 465
Cdd:COG4913   307 LEAELERLEARLDALREELDEL--EAQIRGNGGDRLEQLEREIERLERELEERERRRARLEalLAALGLPLPASAEEFA- 383
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  466 ELRQEREQILQQVGKQRVELEQEIEKAKTEENYIRDRLAlslkennRLENEL--LENAEKlaeyeNLTSKLQRSLEnVLA 543
Cdd:COG4913   384 ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELR-------ELEAEIasLERRKS-----NIPARLLALRD-ALA 450
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  544 EKFGdLDPSSAEFFLQeerLAQMRNEYE------------QQCRLL--QDQVDELQSELEEYQAQGRVlrlpcqnalsee 609
Cdd:COG4913   451 EALG-LDEAELPFVGE---LIEVRPEEErwrgaiervlggFALTLLvpPEHYAAALRWVNRLHLRGRL------------ 514
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  610 ldgHGDGIEQDQEPGSGECNPLNmSIEAELVIEQ------LKEQHHRDLCHLRLELEDKVRHYEK------QLDHTRVAC 677
Cdd:COG4913   515 ---VYERVRTGLPDPERPRLDPD-SLAGKLDFKPhpfrawLEAELGRRFDYVCVDSPEELRRHPRaitragQVKGNGTRH 590
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  678 EKE-QVAMKQKY------EQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQMVFDEEKT-QLQEEL 749
Cdd:COG4913   591 EKDdRRRIRSRYvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVaSAEREI 670
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  750 -RLEHE-----------QELKARLQQAEESF---RQEREGLAQAAAWTEEKARSLTRDLEQShQEQLLSLMEKHALE--- 811
Cdd:COG4913   671 aELEAElerldassddlAALEEQLEELEAELeelEEELDELKGEIGRLEKELEQAEEELDEL-QDRLEAAEDLARLElra 749
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  812 ------KEELRKELSEYHQRELQEGREEMETECNRRVSQIEAQFQADCEKVTERCEQTLQSLEGR--YRQELKDLLDQHL 883
Cdd:COG4913   750 lleerfAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLpeYLALLDRLEEDGL 829
                         570       580       590
                  ....*....|....*....|....*....|....*.
gi 672056299  884 EE-RSQW-----EFEKDELTQECTEAQEQLEEVLQR 913
Cdd:COG4913   830 PEyEERFkellnENSIEFVADLLSKLRRAIREIKER 865
PLN02939 PLN02939
transferase, transferring glycosyl groups
1497-1794 1.71e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 1.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1497 VTTLAKQKDAPSQGEEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQ 1576
Cdd:PLN02939   33 VSCRARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAID 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1577 EELWQKIETIEQEkASIQ-----KMVEKLKKQVSDL-KLKNQQLDSENKELSQKNSQNKEeLKTLNQRLAE-----MLCQ 1645
Cdd:PLN02939  113 NEQQTNSKDGEQL-SDFQledlvGMIQNAEKNILLLnQARLQALEDLEKILTEKEALQGK-INILEMRLSEtdariKLAA 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1646 KEDPGTctsEKWEQENESLKEELDRYKVQTSTLVSSLEAELSEVKLqthiveqENLLLKDELERLKQlhrcpDLSDFQQK 1725
Cdd:PLN02939  191 QEKIHV---EILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKE-------ENMLLKDDIQFLKA-----ELIEVAET 255
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672056299 1726 MCSILSynenLLKEKEVLSEELKSCADKLAESSLLEHRIATIKEerEAWEEQSQDLKSQLALSQEKVQN 1794
Cdd:PLN02939  256 EERVFK----LEKERSLLDASLRELESKFIVAQEDVSKLSPLQY--DCWWEKVENLQDLLDRATNQVEK 318
COG5022 COG5022
Myosin heavy chain [General function prediction only];
712-1347 1.93e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 46.61  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  712 QAAVLKEAHHKASCRHEEEKKQLQMVFDEEKT--------QLQEELRLEHEQELKARLQQAEES----FRQEREGLAQAA 779
Cdd:COG5022   794 RLFIKLQPLLSLLGSRKEYRSYLACIIKLQKTikrekklrETEEVEFSLKAEVLIQKFGRSLKAkkrfSLLKKETIYLQS 873
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  780 AWTEEKARSLTRDLEQ-----SHQEQLLSLMEKHALEkeeLRKELSEYHQRELQEGREEMeTECNRRVSQIEAQFQADCE 854
Cdd:COG5022   874 AQRVELAERQLQELKIdvksiSSLKLVNLELESEIIE---LKKSLSSDLIENLEFKTELI-ARLKKLLNNIDLEEGPSIE 949
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  855 KVTERCEQTLQSLEGRYRQ---ELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKT 931
Cdd:COG5022   950 YVKLPELNKLHEVESKLKEtseEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQ 1029
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  932 HKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQERELREpEHVLCQTGVSEQLgsqqLARLQVEHEQER 1011
Cdd:COG5022  1030 SASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLD-DKQLYQLESTENL----LKTINVKDLEVT 1104
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1012 REMAGKIAALESAHRVSCERADQEKaEMSAEIRRLQSTVKDLQQATS--LLVLQGGCRATAGEEAEGNGALSLLQQGE-- 1087
Cdd:COG5022  1105 NRNLVKPANVLQFIVAQMIKLNLLQ-EISKFLSQLVNTLEPVFQKLSvlQLELDGLFWEANLEALPSPPPFAALSEKRly 1183
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1088 --QLLEENGDVLISLQKAHERAVKEnakMATEISRLQQRLKKLEPGSAISSCLEERMTEISGSSREHAEPVMKRGTATKH 1165
Cdd:COG5022  1184 qsALYDEKSKLSSSEVNDLKNELIA---LFSKIFSGWPRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEK 1260
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1166 FLSDPGDHEAQGLGSTGTSSVQRQECRTEESEASLECFSEL--------------ENSEDTRTESWDLKSQIIQLQEQLT 1231
Cdd:COG5022  1261 LLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALrtkasslrwksateVNYNSEELDDWCREFEISDVDEELE 1340
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1232 VLRadcdRASERKRDLLFDISVLKKKLKMLERL-PEASSKYKVLYEDAARENACLQEELRLMEMRYADS-LDSNKELTAE 1309
Cdd:COG5022  1341 ELI----QAVKVLQLLKDDLNKLDELLDACYSLnPAEIQNLKSRYDPADKENNLPKEILKKIEALLIKQeLQLSLEGKDE 1416
                         650       660       670
                  ....*....|....*....|....*....|....*...
gi 672056299 1310 VYRLQDEMKKMEEvtgTFLSLENSYDEVKLENEKLSAL 1347
Cdd:COG5022  1417 TEVHLSEIFSEEK---SLISLDRNSIYKEEVLSSLSAL 1451
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
558-807 2.12e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.55  E-value: 2.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  558 LQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQ-NALSEELDghgdgieqdqepgsgecnplnmSIE 636
Cdd:COG3206   168 LRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEaKLLLQQLS----------------------ELE 225
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  637 AELVieQLKEQhhrdlchlRLELEDKVRHYEKQLDhtrvacEKEQVAMKQKYEQGMRTLEKQISELQSEIADLQgqaAVL 716
Cdd:COG3206   226 SQLA--EARAE--------LAEAEARLAALRAQLG------SGPDALPELLQSPVIQQLRAQLAELEAELAELS---ARY 286
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  717 KEAHHKAScRHEEEKKQLQMVFDEEKTQLQEELRLEhEQELKARLQQAEESFRQEREGLAQAAAwTEEKARSLTRDLEqS 796
Cdd:COG3206   287 TPNHPDVI-ALRAQIAALRAQLQQEAQRILASLEAE-LEALQAREASLQAQLAQLEARLAELPE-LEAELRRLEREVE-V 362
                         250
                  ....*....|.
gi 672056299  797 HQEQLLSLMEK 807
Cdd:COG3206   363 ARELYESLLQR 373
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
449-1168 2.24e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.65  E-value: 2.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   449 LRKLDEE----------YKERIAALKNELRQEREQILQQvgkQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELl 518
Cdd:pfam15921  226 LRELDTEisylkgrifpVEDQLEALKSESQNKIELLLQQ---HQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQL- 301
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   519 ENAEKLAEYENltSKLQRSLENVlaekfgdldpssaefflqEERLAQMRNEYEQQCRLLQDQVDELQSELeeyqaqgrVL 598
Cdd:pfam15921  302 EIIQEQARNQN--SMYMRQLSDL------------------ESTVSQLRSELREAKRMYEDKIEELEKQL--------VL 353
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   599 rlpcqnALSEELDGHGDGIEQDQEPGsgecnplNMSIEAELVIEQLkeqhHRDLCHLRLELEDKVRHYEKQLDHTrvace 678
Cdd:pfam15921  354 ------ANSELTEARTERDQFSQESG-------NLDDQLQKLLADL----HKREKELSLEKEQNKRLWDRDTGNS----- 411
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   679 keqvamkqkyeqgmRTLEKQISELQSEIADLQGQAAVLKEAhhKASCRHEEEKkqlQMVFDEEKTQlqeelRLEHEQELK 758
Cdd:pfam15921  412 --------------ITIDHLRRELDDRNMEVQRLEALLKAM--KSECQGQMER---QMAAIQGKNE-----SLEKVSSLT 467
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   759 ARLQQAEESFRQEREGLAQAAAWTEEKARSLTrDLEQSHQEQLLSLMEKHAlEKEELRKELsEYHQRELQEGREE----- 833
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKMTLESSERTVS-DLTASLQEKERAIEATNA-EITKLRSRV-DLKLQELQHLKNEgdhlr 544
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   834 -METECNRRVSQIeaqfqADCEKVTERCEQTLQSlegryrqeLKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEV-L 911
Cdd:pfam15921  545 nVQTECEALKLQM-----AEKDKVIEILRQQIEN--------MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFkI 611
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   912 QREKATALARSQEQET----LEKTH-----KERLAI---LSMEREQLLQDLKdlqnTSERQHSLLSDQMLELKRSQEREL 979
Cdd:pfam15921  612 LKDKKDAKIRELEARVsdleLEKVKlvnagSERLRAvkdIKQERDQLLNEVK----TSRNELNSLSEDYEVLKRNFRNKS 687
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   980 REPEhvlcqtgVSEQLGSQQLARLQVEHEQERREMAGKIAALESAHRVSCERADQEKAEmSAEIRRLQSTVKDLQQATSL 1059
Cdd:pfam15921  688 EEME-------TTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAK-RGQIDALQSKIQFLEEAMTN 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1060 L------------VLQGGCRATAGEEAEGNGALSLLQQGEQLLEE---NGDVLI---SLQKAHERAVKENAKMATEISRL 1121
Cdd:pfam15921  760 AnkekhflkeeknKLSQELSTVATEKNKMAGELEVLRSQERRLKEkvaNMEVALdkaSLQFAECQDIIQRQEQESVRLKL 839
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 672056299  1122 QQRL--KKLE-PGSAISSCLEERMTEISGSSREHAEpvMKRGTATKHFLS 1168
Cdd:pfam15921  840 QHTLdvKELQgPGYTSNSSMKPRLLQPASFTRTHSN--VPSSQSTASFLS 887
PTZ00121 PTZ00121
MAEBL; Provisional
656-1395 2.39e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 2.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  656 RLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISELQSEIADlqgqAAVLKEAHHKASCRHEEEKKQLQ 735
Cdd:PTZ00121 1110 KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAED----ARKAEEARKAEDAKKAEAARKAE 1185
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  736 MVFDEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEE---KARSLTRDLEQSHQEQLLSLME------ 806
Cdd:PTZ00121 1186 EVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEakkDAEEAKKAEEERNNEEIRKFEEarmahf 1265
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  807 ---KHALEKEELRKELSEYHQRELQEGREEMETECNRRVsqieaqfqadcEKVTERCEQTLQSLEGRYRQELKDLLDQHL 883
Cdd:PTZ00121 1266 arrQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA-----------DEAKKKAEEAKKADEAKKKAEEAKKKADAA 1334
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  884 EERSQWEFEKDELTQ-ECTEAQEQLEEVLQREKATALARSQEQETLEKTHKErlailsMEREQLLQDLKDLQNTSERQHS 962
Cdd:PTZ00121 1335 KKKAEEAKKAAEAAKaEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK------AEEKKKADEAKKKAEEDKKKAD 1408
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  963 LLSDQMLELKRSQERELREPEhvlcqTGVSEQLGSQQLARLQVEHEQERREMAGKIaalESAHRVSCERADQEKAEMSAE 1042
Cdd:PTZ00121 1409 ELKKAAAAKKKADEAKKKAEE-----KKKADEAKKKAEEAKKADEAKKKAEEAKKA---EEAKKKAEEAKKADEAKKKAE 1480
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1043 IRRLQSTVKDLQQATSLLVLQGGCRATAGEEAEGNGALSLLQQGEQLLE-ENGDVLISLQKAHERAVKENAKMATEISRL 1121
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaEEAKKADEAKKAEEKKKADELKKAEELKKA 1560
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1122 QQRLKKLEPGSAissclEERMTEISGSSREHAEPVMKRGTATKHFLSDPGDHEAQGLGSTGTSSVQRQECRTEESEASLE 1201
Cdd:PTZ00121 1561 EEKKKAEEAKKA-----EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV 1635
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1202 CFSELENSEDTRteswdlKSQIIQLQEQLTVLRAD--CDRASERKR---DLLFDISVLKKKLKMLERLPEASSKYKVLYE 1276
Cdd:PTZ00121 1636 EQLKKKEAEEKK------KAEELKKAEEENKIKAAeeAKKAEEDKKkaeEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1277 DAARENAcLQEELRLMEMRYADSLDSNKELTAEVYRLQDEMKKMEEVTGTFLSLENSYDEVKLENEKLSALVLRLQGKME 1356
Cdd:PTZ00121 1710 KEAEEKK-KAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEE 1788
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*.
gi 672056299 1357 EVLERAALQ-------GDSYSLWEGPSENLEVTSDEKMLELHQTEE 1395
Cdd:PTZ00121 1789 DEKRRMEVDkkikdifDNFANIIEGGKEGNLVINDSKEMEDSAIKE 1834
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
857-1048 2.52e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  857 TERCEQTLQSLEGRYRQ-----ELKDLLDQHLEERSQW--EFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLE 929
Cdd:COG4913   247 AREQIELLEPIRELAERyaaarERLAELEYLRAALRLWfaQRRLELLEAELEELRAELARLEAELERLEARLDALREELD 326
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  930 KTHKERLAILSMEREQLLQDLKDLQNTSERqhsllsdqmlelkrsQERELREPEHVLCQTGVSEQLGSQQLARLQVEHEQ 1009
Cdd:COG4913   327 ELEAQIRGNGGDRLEQLEREIERLERELEE---------------RERRRARLEALLAALGLPLPASAEEFAALRAEAAA 391
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 672056299 1010 ERREMAGKIAALESA---HRVSCERADQEKAEMSAEIRRLQS 1048
Cdd:COG4913   392 LLEALEEELEALEEAlaeAEAALRDLRRELRELEAEIASLER 433
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1430-1640 2.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1430 KAHEIAWFRRKIETHQEKPSVQNRVILEESAALLGLQGTHLQHEATIAELELEKQKLQeltRNLRERVTTLAKQKDAPSQ 1509
Cdd:COG4942    39 LEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---AELEAQKEELAELLRALYR 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1510 GEEEEELKAVMHdlQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQE 1589
Cdd:COG4942   116 LGRQPPLALLLS--PEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEAL 193
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 672056299 1590 KASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLA 1640
Cdd:COG4942   194 KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
411-885 2.77e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 2.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  411 REKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYnlrkldEEYKERIAALKNELRQEREQILQQvgKQRVELEQEIE 490
Cdd:COG4717    64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEEL------EEELEELEAELEELREELEKLEKL--LQLLPLYQELE 135
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  491 KAKTEENYIRDRLalslkenNRLENELLENAEKLAEYENLTSKLQRsLENVLAEKFGDLDPSSAEfflQEERLAQMRNEY 570
Cdd:COG4717   136 ALEAELAELPERL-------EELEERLEELRELEEELEELEAELAE-LQEELEELLEQLSLATEE---ELQDLAEELEEL 204
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  571 EQQCRLLQDQVDELQSELEEYQAQGRVLRLPCQNALSEELDGHGD-------GIEQDQEPGSGECNPLNMSIEAELVIEQ 643
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARlllliaaALLALLGLGGSLLSLILTIAGVLFLVLG 284
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  644 LkeqhhrdLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAmKQKYEQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKA 723
Cdd:COG4717   285 L-------LALLFLLLAREKASLGKEAEELQALPALEELE-EEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA 356
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  724 ScrhEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEEsFRQEREGLAQAAAWTEEKARSLTRDLEQSHQEQLLS 803
Cdd:COG4717   357 E---ELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEE-YQELKEELEELEEQLEELLGELEELLEALDEEELEE 432
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  804 LMEKHALEKEELRKELSEYHQR--ELQEGREEMETEcnRRVSQIEAQFqadcekvtERCEQTLQSLEGRYR--QELKDLL 879
Cdd:COG4717   433 ELEELEEELEELEEELEELREElaELEAELEQLEED--GELAELLQEL--------EELKAELRELAEEWAalKLALELL 502

                  ....*.
gi 672056299  880 DQHLEE 885
Cdd:COG4717   503 EEAREE 508
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
765-981 3.05e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  765 EESFRQEREGLAQAAAWTEEKARSLTRDLEQShQEQLLSLMEKHAL-----EKEELRKELSEYhQRELQEGREEMEtECN 839
Cdd:COG3206   163 EQNLELRREEARKALEFLEEQLPELRKELEEA-EAALEEFRQKNGLvdlseEAKLLLQQLSEL-ESQLAEARAELA-EAE 239
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  840 RRVSQIEAQFQADCEKVTE--------RCEQTLQSLEGRYRQELKDLLDQH-----LEErsqwefEKDELTQECTEAQEQ 906
Cdd:COG3206   240 ARLAALRAQLGSGPDALPEllqspviqQLRAQLAELEAELAELSARYTPNHpdviaLRA------QIAALRAQLQQEAQR 313
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672056299  907 LEEVLQREKATALARSQEQETLEKTHKERLAILSmEREQLLQDLKDLQNTSERQHSLLsdqmleLKRSQERELRE 981
Cdd:COG3206   314 ILASLEAELEALQAREASLQAQLAQLEARLAELP-ELEAELRRLEREVEVARELYESL------LQRLEEARLAE 381
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
389-590 3.75e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  389 QAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEyNLRKLdeeyKERIAALKNELR 468
Cdd:COG4942    26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA-ELAEL----EKEIAELRAELE 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  469 QEREQILQQVGKQ-----------------------RVELEQEIEKAKTEEnyiRDRLALSLKENNRLENELLENAEKLA 525
Cdd:COG4942   101 AQKEELAELLRALyrlgrqpplalllspedfldavrRLQYLKYLAPARREQ---AEELRADLAELAALRAELEAERAELE 177
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672056299  526 EYENLTSKLQRSLENVLAEKFGDLDPSSAEFFLQEERLAQMRNEYEQqcrlLQDQVDELQSELEE 590
Cdd:COG4942   178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE----LEALIARLEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
755-959 4.01e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 4.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  755 QELKARLQQAEESFRQEREGLAQaaawTEEKARSLTRDLEQSHQEQLLSLMEKHALEKE--ELRKELSEYHQR--ELQEG 830
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAA----LKKEEKALLKQLAALERRIAALARRIRALEQElaALEAELAELEKEiaELRAE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  831 REEMETECNRRVSQIEAQFQADCEKVTERCEQTLQSLE-----GRYRQELKDLLDQHLEERSQWEFEKDELTQEcTEAQE 905
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRrlqylKYLAPARREQAEELRADLAELAALRAELEAE-RAELE 177
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 672056299  906 QLEEVLQREKATALARSQEQETLEKTHKERLAILSMEREQLLQDLKDLQNTSER 959
Cdd:COG4942   178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
684-1124 4.15e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 4.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   684 MKQKYEQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKkQLQMVFDEEKTQLQEELRLEHEQEL------ 757
Cdd:TIGR00618  213 MPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQ-LLKQLRARIEELRAQEAVLEETQERinrark 291
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   758 KARLQQAEESFRQEREGLAQAAAWTEEKARSLTRDLEQ--SHQEQLLSLMEKHALEKEELRKELSEYHQRELQEGREEM- 834
Cdd:TIGR00618  292 AAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKraAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREIs 371
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   835 --ETECNRRVSQIEAQFQADCEKvtercEQTLQSLEGRYRQELKDLLDQHLEERSqwefEKDELTQecTEAQEQLEEVLQ 912
Cdd:TIGR00618  372 cqQHTLTQHIHTLQQQKTTLTQK-----LQSLCKELDILQREQATIDTRTSAFRD----LQGQLAH--AKKQQELQQRYA 440
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   913 REKATALARSQEQETLEKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQ---ERELREPEHVLCQT 989
Cdd:TIGR00618  441 ELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPcplCGSCIHPNPARQDI 520
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   990 GVSEQLGSQQLARLQ--VEHEQERREMAGK-IAALESAHRVS--CERADQEKAEMSAEIRRLQSTVKDLQQATSLLVLQG 1064
Cdd:TIGR00618  521 DNPGPLTRRMQRGEQtyAQLETSEEDVYHQlTSERKQRASLKeqMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLT 600
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672056299  1065 gcraTAGEEAEGNGALSLLQQGEQLLEENGDVLISL---QKAHERAVKENAKMATEISRLQQR 1124
Cdd:TIGR00618  601 ----EKLSEAEDMLACEQHALLRKLQPEQDLQDVRLhlqQCSQELALKLTALHALQLTLTQER 659
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
686-1125 4.71e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 45.28  E-value: 4.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  686 QKYEQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAE 765
Cdd:COG5278    79 EPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARL 158
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  766 ESFRQEREGLAQAAAWTEEKARSLTRDLEQSHQEQLLSLMEKHALEKEELRKELSEYHQRELQEGREEMETECNRRVSQI 845
Cdd:COG5278   159 LLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAAL 238
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  846 EAQFQADCEKVTERCEQTLQSLEGRYRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQ 925
Cdd:COG5278   239 ALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAA 318
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  926 ETLEKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQERELREPEHVLCQTGVSEQLGSQQLARLQV 1005
Cdd:COG5278   319 AAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAA 398
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1006 EHEQERREMAGKIAALESAHRVSCERADQEKAEMSAEIRRLQSTVKDLQQATSLLVLQGGCRATAGEEAEGNGALSLLQQ 1085
Cdd:COG5278   399 AAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALA 478
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 672056299 1086 GEQLLEENGDVLISLQKAHERAVKENAKMATEISRLQQRL 1125
Cdd:COG5278   479 AAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALA 518
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
681-918 4.73e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 4.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  681 QVAMKQKYEQGMRTLEKQISELQSEIADLQGQAAVLKEAHHKASCRHEEEKKQLQmVFDEEKTQLQEELRleheqELKAR 760
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR-ALEQELAALEAELA-----ELEKE 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  761 LQQAEESFRQEREGLAQ--AAAWTEEKARSLTRDLEQSHQEQLLSLMEKHALEKEELRKELSEY--HQRELQEGREEMET 836
Cdd:COG4942    92 IAELRAELEAQKEELAEllRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELraDLAELAALRAELEA 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  837 ECNRRVSQIEAQfqadcekvtERCEQTLQSLegryRQELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKA 916
Cdd:COG4942   172 ERAELEALLAEL---------EEERAALEAL----KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238

                  ..
gi 672056299  917 TA 918
Cdd:COG4942   239 AA 240
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
496-1045 4.94e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.21  E-value: 4.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   496 ENYIRDRLALSLKENNRLENELLENAEKlaEYENLTSKLQRSlenvlaeKFGDLDPSSAEFFLQEERlAQMRNEYEQQCR 575
Cdd:pfam12128  224 EHWIRDIQAIAGIMKIRPEFTKLQQEFN--TLESAELRLSHL-------HFGYKSDETLIASRQEER-QETSAELNQLLR 293
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   576 LLQDQVDELQSELEE---------YQAQGRVLRLPCQNALSEELDGHGDGIEQDQEPG-SGECNPLNMSIEAEL-VIEQL 644
Cdd:pfam12128  294 TLDDQWKEKRDELNGelsaadaavAKDRSELEALEDQHGAFLDADIETAAADQEQLPSwQSELENLEERLKALTgKHQDV 373
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   645 KEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKqkyeqgmrtlekqiselqseiADLQGQAAVLKEAHHKAS 724
Cdd:pfam12128  374 TAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAE---------------------DDLQALESELREQLEAGK 432
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   725 CRHEEEKKQLQMVFDEEKTQL-------QEELRLEHEQELKARLQQAEESFRQEREGL----AQAAAWTEEKARSLTR-- 791
Cdd:pfam12128  433 LEFNEEEYRLKSRLGELKLRLnqatatpELLLQLENFDERIERAREEQEAANAEVERLqselRQARKRRDQASEALRQas 512
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   792 ----DLEQSHQEQLLSLMEKHALEKEELRKELSEYHQ-------RELQeGREEMETECNR--------------RVSQIE 846
Cdd:pfam12128  513 rrleERQSALDELELQLFPQAGTLLHFLRKEAPDWEQsigkvisPELL-HRTDLDPEVWDgsvggelnlygvklDLKRID 591
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   847 AQFQADCEKVTER----CEQTLQSLEGRYRQELKDL--LDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQREKataLA 920
Cdd:pfam12128  592 VPEWAASEEELRErldkAEEALQSAREKQAAAEEQLvqANGELEKASREETFARTALKNARLDLRRLFDEKQSEK---DK 668
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   921 RSQEQETLEKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQERELREPEHVLCQTGVSEQlgSQQL 1000
Cdd:pfam12128  669 KNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARR--SGAK 746
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 672056299  1001 ARLQVEHEQERREMAGKIAALESAHRVSCERADQEKAEMSAEIRR 1045
Cdd:pfam12128  747 AELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRR 791
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
1544-1835 5.89e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.01  E-value: 5.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1544 LQEENSILRNEITTLNEEDSISNLKLEELNGS----QEELWQKIETI---EQEKASIQKMVEKLKKQVSDLKLKNQQLDS 1616
Cdd:TIGR04523   73 SNNKIKILEQQIKDLNDKLKKNKDKINKLNSDlskiNSEIKNDKEQKnklEVELNKLEKQKKENKKNIDKFLTEIKKKEK 152
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1617 ENKELSQKNSQNKEELKTLNQRLAEMLCQKedpgtctsEKWEQENESLKEELDRYKVQTSTLVS------SLEAELSEVK 1690
Cdd:TIGR04523  153 ELEKLNNKYNDLKKQKEELENELNLLEKEK--------LNIQKNIDKIKNKLLKLELLLSNLKKkiqknkSLESQISELK 224
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1691 LQTHIVEQENLLLKDELERLKQlhrcpDLSDFQQKMCSILSYNENLLKEKEVLSEELKSCADKLAEsslLEHRIATIKEE 1770
Cdd:TIGR04523  225 KQNNQLKDNIEKKQQEINEKTT-----EISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE---LEKQLNQLKSE 296
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1771 REAWEEQSQ-----DLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQLQ 1835
Cdd:TIGR04523  297 ISDLNNQKEqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELE 366
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
1529-1800 5.92e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 45.04  E-value: 5.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1529 EMQRKVELLRYeSEKLQEENSILRNEITTLneEDSISNLkleelngsQEELWQKIETIEQEKASIQKMVEKLKKQVSDL- 1607
Cdd:TIGR01612 1088 EIKEKLKHYNF-DDFGKEENIKYADEINKI--KDDIKNL--------DQKIDHHIKALEEIKKKSENYIDEIKAQINDLe 1156
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1608 KLKNQQLDSENKELSQKNSQN-----------KEELKTLNQRLAEMLCQK---EDPGTCTSEKWEQENESLKEELDRYKV 1673
Cdd:TIGR01612 1157 DVADKAISNDDPEEIEKKIENivtkidkkkniYDEIKKLLNEIAEIEKDKtslEEVKGINLSYGKNLGKLFLEKIDEEKK 1236
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1674 QTSTLVSSLEA---ELSEVKLQTHIVEQENLLLKDELERLKQLhrcpDLSDFQQKMCSILSYNENllkekEVLSEeLKSC 1750
Cdd:TIGR01612 1237 KSEHMIKAMEAyieDLDEIKEKSPEIENEMGIEMDIKAEMETF----NISHDDDKDHHIISKKHD-----ENISD-IREK 1306
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 672056299  1751 ADKLAESSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILK 1800
Cdd:TIGR01612 1307 SLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILK 1356
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1511-1708 8.19e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 8.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1511 EEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEK 1590
Cdd:COG4372    31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1591 ASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEDPGTCTSEKWEQENESLKEELDR 1670
Cdd:COG4372   111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLK 190
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 672056299 1671 YKVQTSTLVSSLEAELSEVKLQTHIVEQENLLLKDELE 1708
Cdd:COG4372   191 EANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLE 228
PTZ00121 PTZ00121
MAEBL; Provisional
410-994 9.55e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 9.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  410 VREKEKLR--SDLDKAEKLKSLMASEVDDHHA--AIERRNEYNLRKLDE----EYKERIAALKNELRQEREQILQQVGKQ 481
Cdd:PTZ00121 1211 ERKAEEARkaEDAKKAEAVKKAEEAKKDAEEAkkAEEERNNEEIRKFEEarmaHFARRQAAIKAEEARKADELKKAEEKK 1290
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  482 RV-ELEQEIEKAKTEENYIR---DRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLENVLAEKFGDLDPSSAEFF 557
Cdd:PTZ00121 1291 KAdEAKKAEEKKKADEAKKKaeeAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  558 LQEERLAQMRNEYEQQCRLLQdQVDELQSELEEYQAQGRVLRLpcqnalSEELDGHGDGIEQDQEPGSgecnplnmsiEA 637
Cdd:PTZ00121 1371 KKKEEAKKKADAAKKKAEEKK-KADEAKKKAEEDKKKADELKK------AAAAKKKADEAKKKAEEKK----------KA 1433
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  638 ELVIEQLKEQHHRDLCHLRLELEDKVRHYEKQLDHTRVACE-KEQVAMKQKYEQGMRTLE--KQISELQSEIADLQGQAA 714
Cdd:PTZ00121 1434 DEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEaKKKAEEAKKADEAKKKAEeaKKKADEAKKAAEAKKKAD 1513
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  715 VLKEAHHKascRHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEEKARSLTRDLE 794
Cdd:PTZ00121 1514 EAKKAEEA---KKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  795 QSHQEQLLSLMEKHALEK-EELRKELSEYHQRElQEGREEMETECNRRVSQIEAQFQADCEKVTERCEQTLQSLEGRYRQ 873
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKaEEAKKAEEAKIKAE-ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK 1669
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  874 ELKDLLDQHlEERSQWEFEKDELTQECTEAQEQLE-EVLQREKATALARSQEQETLEKTHKERLAILSMEREQLLQDLKD 952
Cdd:PTZ00121 1670 AEEDKKKAE-EAKKAEEDEKKAAEALKKEAEEAKKaEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 672056299  953 LQNTSERQHSLLSDQMLELKRSQerELREPEHVLCQTGVSEQ 994
Cdd:PTZ00121 1749 AKKDEEEKKKIAHLKKEEEKKAE--EIRKEKEAVIEEELDEE 1788
PRK00106 PRK00106
ribonuclease Y;
726-874 1.20e-03

ribonuclease Y;


Pssm-ID: 178867 [Multi-domain]  Cd Length: 535  Bit Score: 43.70  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  726 RHEEEKKQLQMVFDEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEEKARSLTRDLEQ--------SH 797
Cdd:PRK00106   50 KAERDAEHIKKTAKRESKALKKELLLEAKEEARKYREEIEQEFKSERQELKQIESRLTERATSLDRKDENlsskektlES 129
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  798 QEQLLSLMEKHALEKEELRKELSEYHQRELQ--------EGREEMETECNRRVSQIEAQFQADCEK-VTERCE------- 861
Cdd:PRK00106  130 KEQSLTDKSKHIDEREEQVEKLEEQKKAELErvaalsqaEAREIILAETENKLTHEIATRIREAEReVKDRSDkmakdll 209
                         170
                  ....*....|....
gi 672056299  862 -QTLQSLEGRYRQE 874
Cdd:PRK00106  210 aQAMQRLAGEYVTE 223
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
434-800 1.27e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.96  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   434 VDDHHAAIERRNEYNLRKLDEEykeriaalknELRQEREQILQQVGKQRveleqEIEKAKTEENYIRDRLALSLKENNRL 513
Cdd:pfam17380  278 VQHQKAVSERQQQEKFEKMEQE----------RLRQEKEEKAREVERRR-----KLEEAEKARQAEMDRQAAIYAEQERM 342
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   514 ENELLENAEKLAEYENltsklQRSLENVLAEKFG-DLDPSSAEFFLQEERlaQMRNEYEQQ----CRLLQDQVDELQSEL 588
Cdd:pfam17380  343 AMERERELERIRQEER-----KRELERIRQEEIAmEISRMRELERLQMER--QQKNERVRQeleaARKVKILEEERQRKI 415
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   589 EEYQAQGRVLRLPCQNALSEELdghgdgieqdqepgsgecnplnmsieaelviEQLKEQHHRDLCHLRLELEDK------ 662
Cdd:pfam17380  416 QQQKVEMEQIRAEQEEARQREV-------------------------------RRLEEERAREMERVRLEEQERqqqver 464
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   663 VRHYEKQLDHTRVACEKEQVAMKQKYEQGMRTLEKQISElqseiadlqGQAAVLKEAHHKASCRHEEEKKQLQMVFDEEK 742
Cdd:pfam17380  465 LRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE---------RKQAMIEEERKRKLLEKEMEERQKAIYEEERR 535
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 672056299   743 TQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAaawteEKARSLTRDLEQSHQEQ 800
Cdd:pfam17380  536 REAEEERRKQQEMEERRRIQEQMRKATEERSRLEAM-----EREREMMRQIVESEKAR 588
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1472-1835 1.54e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.49  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1472 HEATIAELELEKQKLQELTRNLRERVTTLAKQKDAPSQGEEE-EELKAVMHDLQITCGEMQRKVELLRYESEKLQEENSI 1550
Cdd:PRK02224  211 LESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREElETLEAEIEDLRETIAETEREREELAEEVRDLRERLEE 290
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1551 LRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNS---- 1626
Cdd:PRK02224  291 LEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAeles 370
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1627 ----------QNKEELKTLNQRLAEMLCQKEDPGTcTSEKWEQENESLKEELDRYKVQtstlVSSLEAELSEVklqthiv 1696
Cdd:PRK02224  371 eleeareaveDRREEIEELEEEIEELRERFGDAPV-DLGNAEDFLEELREERDELRER----EAELEATLRTA------- 438
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1697 eQENLllkDELERLKQLHRCPD-------------LSDFQQKMCSIlsynENLLKEKEVLSEELKSCADKLAESSLLEHR 1763
Cdd:PRK02224  439 -RERV---EEAEALLEAGKCPEcgqpvegsphvetIEEDRERVEEL----EAELEDLEEEVEEVEERLERAEDLVEAEDR 510
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672056299 1764 IATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQLQ 1835
Cdd:PRK02224  511 IERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA 582
PRK12704 PRK12704
phosphodiesterase; Provisional
803-952 1.74e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 1.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  803 SLMEKHALEKEELRKELSEYHQRELQEGREEMETECNRRVSQIEAQFQADcekVTERcEQTLQSLEGRYRQElKDLLDQH 882
Cdd:PRK12704   27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKE---LRER-RNELQKLEKRLLQK-EENLDRK 101
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672056299  883 LEErsqwefekdeLTQECTEAQEQLEEVLQREKaTALARSQEQETLEKTHKERL---AILSME--REQLLQDLKD 952
Cdd:PRK12704  102 LEL----------LEKREEELEKKEKELEQKQQ-ELEKKEEELEELIEEQLQELeriSGLTAEeaKEILLEKVEE 165
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
454-594 2.29e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  454 EEYKERIAALKNELRQEREQiLQQVGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSK 533
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKE-LAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672056299  534 LQRSLENVL--AEKFGDLDPS----SAEFFLQEERLAQMRNEYEQQcrlLQDQVDELQSELEEYQAQ 594
Cdd:COG4942   102 QKEELAELLraLYRLGRQPPLalllSPEDFLDAVRRLQYLKYLAPA---RREQAEELRADLAELAAL 165
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
661-1026 2.49e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.02  E-value: 2.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  661 DKVRHYEKQLDHTRVACEKEQVAMKQKYEQgmRTLEKQISELQSEIADLQGQAAVLKEAHHKAS---------CRHEEEK 731
Cdd:COG3096   272 DYMRHANERRELSERALELRRELFGARRQL--AEEQYRLVEMARELEELSARESDLEQDYQAASdhlnlvqtaLRQQEKI 349
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  732 KQLQMVFDE--EKTQLQEELRLE-HEQ--ELKARLQQAEESFRQEREGLA----------------QAAAWTEEKARSLT 790
Cdd:COG3096   350 ERYQEDLEEltERLEEQEEVVEEaAEQlaEAEARLEAAEEEVDSLKSQLAdyqqaldvqqtraiqyQQAVQALEKARALC 429
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  791 rDLEQSHQEQLLSLMEKHALEKEELRKELSEYHQReLQEGREEmetecnrrVSQIEAQFQADC----EKVTERCEQTLQS 866
Cdd:COG3096   430 -GLPDLTPENAEDYLAAFRAKEQQATEEVLELEQK-LSVADAA--------RRQFEKAYELVCkiagEVERSQAWQTARE 499
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  867 LEGRYRqELKDLLDQHLEERSQW-EFEKDELTQEctEAQEQLEEVLQR-----EKATALARSQ-EQETLEKTHKERLAIL 939
Cdd:COG3096   500 LLRRYR-SQQALAQRLQQLRAQLaELEQRLRQQQ--NAERLLEEFCQRigqqlDAAEELEELLaELEAQLEELEEQAAEA 576
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  940 SMEREQLLQDLKDLQntseRQHSLLSDQMLELKRSQERELREPEHVLCQTGVSEQLGS--QQLARLQVEHEQERREMAGK 1017
Cdd:COG3096   577 VEQRSELRQQLEQLR----ARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAamQQLLEREREATVERDELAAR 652

                  ....*....
gi 672056299 1018 IAALESAHR 1026
Cdd:COG3096   653 KQALESQIE 661
PTZ00121 PTZ00121
MAEBL; Provisional
884-1710 2.49e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 2.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  884 EERSQWEFEKDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKTHKERlailsmeREQLLQDLKDLQNTSERQHSL 963
Cdd:PTZ00121 1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAK-------RVEIARKAEDARKAEEARKAE 1173
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  964 LSDQMLELKRSQEreLREPEHVLCQTGVSEQLGSQQLARLQVEHEQERREMAGKIAALESAHRVsceRADQEKAEMSAEI 1043
Cdd:PTZ00121 1174 DAKKAEAARKAEE--VRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEA---KKDAEEAKKAEEE 1248
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1044 RRLQSTVKDLQQATSLLVlqggcRATAGEEAEGNGALSLLQQGEQLLEENgdvliSLQKAHE-RAVKENAKMATEISRLQ 1122
Cdd:PTZ00121 1249 RNNEEIRKFEEARMAHFA-----RRQAAIKAEEARKADELKKAEEKKKAD-----EAKKAEEkKKADEAKKKAEEAKKAD 1318
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1123 QRLKKLEPGSAISSCLEERMTEisgsSREHAEPVMKRGTATKHflsdpgdhEAQGLGSTGTSSVQRQECRTEESEASLEC 1202
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEE----AKKAAEAAKAEAEAAAD--------EAEAAEEKAEAAEKKKEEAKKKADAAKKK 1386
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1203 FSELENSEDTRTESWDLKSQIIQLQ----EQLTVLRADCDRASERKRDLLFDISVLKKKLKMLERLPEASSKYKVLYEDA 1278
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEEDKKKADELKkaaaAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKA 1466
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1279 ARENACLQEELRLMEMRYADSLDSNKEltaEVYRLQDEMKKMEEVTGTFLSLENS-----YDEVKLENEKLSALVLRlqg 1353
Cdd:PTZ00121 1467 EEAKKADEAKKKAEEAKKADEAKKKAE---EAKKKADEAKKAAEAKKKADEAKKAeeakkADEAKKAEEAKKADEAK--- 1540
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1354 KMEEVLERAALQgdsyslwegPSENLEVTSDEKMLELHQTEEECTPEVMSRHHI---IEECRQETRC----------CEQ 1420
Cdd:PTZ00121 1541 KAEEKKKADELK---------KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakkAEEARIEEVMklyeeekkmkAEE 1611
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1421 GSTQLLAGIKAHEIawfrRKIETHQEKPSVQNRVILEESAALLGLQGthlQHEATIAELELEKQKLQELTRNLRERVTTL 1500
Cdd:PTZ00121 1612 AKKAEEAKIKAEEL----KKAEEEKKKVEQLKKKEAEEKKKAEELKK---AEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1501 AKQKDAPSQGEEEEELKAVMHDLQITCGEMQRKVELLRyeseKLQEENSILRNEITTLNEEDsisNLKLEELNGSQEELw 1580
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELK----KAEEENKIKAEEAKKEAEED---KKKAEEAKKDEEEK- 1756
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1581 QKIETIEQEKASIQKMVEKLKKQV--SDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEML-CQKEDPGTCTSEKW 1657
Cdd:PTZ00121 1757 KKIAHLKKEEEKKAEEIRKEKEAVieEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVInDSKEMEDSAIKEVA 1836
                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 672056299 1658 EQENESLKE--ELDRYKVQTSTLVSSLEAELSEVKLQTHIVE--QENLLLKDELERL 1710
Cdd:PTZ00121 1837 DSKNMQLEEadAFEKHKFNKNNENGEDGNKEADFNKEKDLKEddEEEIEEADEIEKI 1893
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1664-1944 2.86e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 2.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1664 LKEELDRYKVQTSTL--------VSSLEAELSEVKLQTHIVEQENLLLKDELERLKQlhrcpDLSDFQQKMCSILSYNEN 1735
Cdd:COG1196   218 LKEELKELEAELLLLklreleaeLEELEAELEELEAELEELEAELAELEAELEELRL-----ELEELELELEEAQAEEYE 292
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1736 LLKEKEVLSEELKSCADKLAEsslLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQV 1815
Cdd:COG1196   293 LLAELARLEQDIARLEERRRE---LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1816 TRQEKEALKQEVMSLHLQLQNAIDKdwVSETATHLSGLQGQQKRLSwNKLDHLMSEEPELLcQESKRLQTVVQNTQADLT 1895
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEALRA--AAELAAQLEELEEAEEALL-ERLERLEEELEELE-EALAELEEEEEEEEEALE 445
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 672056299 1896 HSREKIRQLESNLLptKHQKQLNQSCTVKPIEQEKLALKRECEQSRKER 1944
Cdd:COG1196   446 EAAEEEAELEEEEE--ALLELLAELLEEAALLEAALAELLEELAEAAAR 492
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1568-1786 2.99e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 2.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1568 KLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKE 1647
Cdd:COG4942    35 EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALY 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1648 DPGTCTSEKWEQENESLKEELDRYKVqTSTLVSSLEAELSEVKLQTHIVEQENLLLKDELERLKQLHrcpdlsdfqqkmc 1727
Cdd:COG4942   115 RLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAELEAERAELEALL------------- 180
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 672056299 1728 silsynENLLKEKEVLSEELKSCADKLAEsslLEHRIATIKEEREAWEEQSQDLKSQLA 1786
Cdd:COG4942   181 ------AELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIA 230
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
1571-1806 3.03e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 42.71  E-value: 3.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1571 ELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENKELSQKNSQNKEELKTLnqrlaemlcqkedpg 1650
Cdd:pfam05667  311 EAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEEL--------------- 375
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1651 tctsekwEQENESLKEEldrYKVQTSTLVSSLEAELSEVKLQTHIVEQENLLLkdELERLKQLHRCPDLSDFQQkmcsil 1730
Cdd:pfam05667  376 -------KEQNEELEKQ---YKVKKKTLDLLPDAEENIAKLQALVDASAQRLV--ELAGQWEKHRVPLIEEYRA------ 437
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672056299  1731 synenlLKEKevlseelksCADKLAESsllEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQM 1806
Cdd:pfam05667  438 ------LKEA---------KSNKEDES---QRKLEEIKELREKIKEVAEEAKQKEELYKQLVAEYERLPKDVSRSA 495
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
398-1061 3.23e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.63  E-value: 3.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  398 EIRHLLERVDQvvrekekLRSDLDKAEKLkslmaseVDDHHAAIERRNEYNLR-KLDEEYKERIAALKNELRQEREQILQ 476
Cdd:COG3096   506 SQQALAQRLQQ-------LRAQLAELEQR-------LRQQQNAERLLEEFCQRiGQQLDAAEELEELLAELEAQLEELEE 571
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  477 QV---GKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKLQRSLEnvlaekfgdldpss 553
Cdd:COG3096   572 QAaeaVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLE-------------- 637
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  554 aefflQEERLAQMRNEYEQQCRLLQDQVDELQseleeyQAQG----RVLRLpcQNALSEEL--DGHGDGIEQDQEPGSGE 627
Cdd:COG3096   638 -----REREATVERDELAARKQALESQIERLS------QPGGaedpRLLAL--AERLGGVLlsEIYDDVTLEDAPYFSAL 704
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  628 CNPLNMSI---EAELVIEQLkeqHHRDLCHLRLEL--------EDKVRHYEKQLDHTRVACEKEQVamkqKYEQ------ 690
Cdd:COG3096   705 YGPARHAIvvpDLSAVKEQL---AGLEDCPEDLYLiegdpdsfDDSVFDAEELEDAVVVKLSDRQW----RYSRfpevpl 777
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  691 -GMRTLEKQISELQSEiadlqgqAAVLKEAHHKAScrheeekkqlqmvFDEEKTQlqeelRLEH--EQELKARLQQA--- 764
Cdd:COG3096   778 fGRAAREKRLEELRAE-------RDELAEQYAKAS-------------FDVQKLQ-----RLHQafSQFVGGHLAVAfap 832
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  765 --EESFRQEREGLAQAaawteEKARSLTRDLEQSHQEQLLSLMEKHALekeeLRKELS-------EYHQRELQEGREEME 835
Cdd:COG3096   833 dpEAELAALRQRRSEL-----ERELAQHRAQEQQLRQQLDQLKEQLQL----LNKLLPqanlladETLADRLEELREELD 903
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  836 tecnrrvsqiEAQfqaDCEKVTERCEQTLQSLEgryrqELKDLLDQHLEERSQWEFEKDELTQECTEAQEQ---LEEVLQ 912
Cdd:COG3096   904 ----------AAQ---EAQAFIQQHGKALAQLE-----PLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQifaLSEVVQ 965
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  913 REkaTALARSQEQETLEKTH------KERLAILSMEREQLLQDLKDLQNTSERQHSLLSDqmleLKRSQE---RELREPE 983
Cdd:COG3096   966 RR--PHFSYEDAVGLLGENSdlneklRARLEQAEEARREAREQLRQAQAQYSQYNQVLAS----LKSSRDakqQTLQELE 1039
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672056299  984 HVLCQTGVSEQLGSQQLARLQV-EHEQERREMAGKIAALEsAHRVSCEradqekAEMSAEIRRLQSTVKDLQQATSLLV 1061
Cdd:COG3096  1040 QELEELGVQADAEAEERARIRRdELHEELSQNRSRRSQLE-KQLTRCE------AEMDSLQKRLRKAERDYKQEREQVV 1111
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
414-976 3.35e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 3.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   414 EKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEyNLRKLDEEYKERIAALKNELRQErEQILQQVGKQRVELEQEIEKAK 493
Cdd:pfam01576  144 EDQNSKLSKERKLLEERISEFTSNLAEEEEKAK-SLSKLKNKHEAMISDLEERLKKE-EKGRQELEKAKRKLEGESTDLQ 221
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   494 TEENYIRDRLALSLKENNRLENEL---LENAEKLAEYENLTSKLQRSLENVLAEKFGDLdpssaefflqeERLAQMRNEY 570
Cdd:pfam01576  222 EQIAELQAQIAELRAQLAKKEEELqaaLARLEEETAQKNNALKKIRELEAQISELQEDL-----------ESERAARNKA 290
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   571 EQQCRLLQDQVDELQSELEEyqaqgrvlrlpcqnalseeldghgdgieqdqepgsgecnplnmSIEAELVIEQLKEQHHR 650
Cdd:pfam01576  291 EKQRRDLGEELEALKTELED-------------------------------------------TLDTTAAQQELRSKREQ 327
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   651 DLCHLRLELEDKVRHYEKQLDHTRVACEKEQVAMKQKYEQGMR---TLEKQISELQSEIADLQGQAAVLKEAHHKASCRH 727
Cdd:pfam01576  328 EVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRnkaNLEKAKQALESENAELQAELRTLQQAKQDSEHKR 407
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   728 EEEKKQLQmvfdeektqlqeELRLEHEQELKARLQQAEESFR--QEREGLAQAAAWTEEKARSLTRDLEQSHQEqllsLM 805
Cdd:pfam01576  408 KKLEGQLQ------------ELQARLSESERQRAELAEKLSKlqSELESVSSLLNEAEGKNIKLSKDVSSLESQ----LQ 471
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   806 EKHALEKEELRKELSEYHQ-----------RELQEGREEMETECNRRVSQIEAQFqADCEKVTERCEQTLQSLEGRYRQE 874
Cdd:pfam01576  472 DTQELLQEETRQKLNLSTRlrqledernslQEQLEEEEEAKRNVERQLSTLQAQL-SDMKKKLEEDAGTLEALEEGKKRL 550
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   875 LKDL--LDQHLEERSQ----WEFEKDELTQECTEA-----------------QEQLEEVLQREKATALARSQEQETLEKT 931
Cdd:pfam01576  551 QRELeaLTQQLEEKAAaydkLEKTKNRLQQELDDLlvdldhqrqlvsnlekkQKKFDQMLAEEKAISARYAEERDRAEAE 630
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 672056299   932 HKERLA-ILSMEREqlLQDLKDLQNTSERQHSLLSDQMLELKRSQE 976
Cdd:pfam01576  631 AREKETrALSLARA--LEEALEAKEELERTNKQLRAEMEDLVSSKD 674
PTZ00121 PTZ00121
MAEBL; Provisional
1482-1981 3.46e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 3.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1482 EKQKLQELTRNLRERVTTLAKQKdaPSQGEEEEELKAVMHDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEE 1561
Cdd:PTZ00121 1288 EKKKADEAKKAEEKKKADEAKKK--AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1562 DSISNLKLEELNGSQEELWQKIEtiEQEKA-SIQKMVEKLKKQVSDLKLK---NQQLDSENKELSQKNSQNKEELKTLNQ 1637
Cdd:PTZ00121 1366 AEAAEKKKEEAKKKADAAKKKAE--EKKKAdEAKKKAEEDKKKADELKKAaaaKKKADEAKKKAEEKKKADEAKKKAEEA 1443
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1638 RLAEMLCQKEDPGTCTSEKWEQENESLKEELDRYKVQTSTLVSSLEAELSEVKLQTHIVEQENLLLK--DELERLKQLHR 1715
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKkaDEAKKAEEAKK 1523
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1716 CPDLSDFQQKMcsilsynenllKEKEVLSEELKSCADKL--AESSLLEHRIATIKEEREAWEEQSQDLKSQLALSQEKVQ 1793
Cdd:PTZ00121 1524 ADEAKKAEEAK-----------KADEAKKAEEKKKADELkkAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA 1592
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1794 NLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSLHLQLQNAIDKDWVSETATHLSGLQGQQKRLSWNKLDHLMSEEP 1873
Cdd:PTZ00121 1593 RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE 1672
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1874 E-LLCQESKRLQTVVQNTQADLTHSREKIRQLESnlLPTKHQKQLNQSCTVKPIEQEKlalKRECEQSRKERSPTSRKVS 1952
Cdd:PTZ00121 1673 DkKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE--LKKKEAEEKKKAEELKKAEEEN---KIKAEEAKKEAEEDKKKAE 1747
                         490       500       510
                  ....*....|....*....|....*....|
gi 672056299 1953 QMSSLERELETI-HLENEGLKKKQVRLDEK 1981
Cdd:PTZ00121 1748 EAKKDEEEKKKIaHLKKEEEKKAEEIRKEK 1777
PRK11281 PRK11281
mechanosensitive channel MscK;
861-1122 3.78e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  861 EQTLQSLEGRYRQELK-DLLDQHLEErsqwefekdeLTQECTEAQEQLEevlqrekatALARSQEQETLEKTHKERLAIL 939
Cdd:PRK11281   66 EQTLALLDKIDRQKEEtEQLKQQLAQ----------APAKLRQAQAELE---------ALKDDNDEETRETLSTLSLRQL 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  940 SMEREQLLQDLKDLQNT--------------SERQHSLLSDQmleLKRSQE------------RELREPEHVLCQTgvse 993
Cdd:PRK11281  127 ESRLAQTLDQLQNAQNDlaeynsqlvslqtqPERAQAALYAN---SQRLQQirnllkggkvggKALRPSQRVLLQA---- 199
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  994 qlgsqQLARLQVEHEQERREMAG--KIAALESAHRvsceradqekAEMSAEIRRLQSTVKDLQ-------------QATS 1058
Cdd:PRK11281  200 -----EQALLNAQNDLQRKSLEGntQLQDLLQKQR----------DYLTARIQRLEHQLQLLQeainskrltlsekTVQE 264
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672056299 1059 LLVLQGGCRATAG----EEAEGNGALS--LLQQGEQLLEENGD------VLISLQKAhERAVKEnakmatEISRLQ 1122
Cdd:PRK11281  265 AQSQDEAARIQANplvaQELEINLQLSqrLLKATEKLNTLTQQnlrvknWLDRLTQS-ERNIKE------QISVLK 333
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
346-933 4.04e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 4.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  346 EEGIENSQEILKALDFSLDGNINLTELTLALENELlvtknGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEK 425
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELI-----KEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE 235
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  426 LKSLMAsevddhhaaierrneyNLRKLDEEYKERIAALKNELRQEREQIlqqvgkqrVELEQEIEKAKTEENYIRDrLAL 505
Cdd:PRK03918  236 LKEEIE----------------ELEKELESLEGSKRKLEEKIRELEERI--------EELKKEIEELEEKVKELKE-LKE 290
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  506 SLKENNRLENELLENAEKLAEYENLTSKLQRSLENVlAEKFGDLDPSSAEFFLQEERLAQMRNEYE--QQCRLLQDQVDE 583
Cdd:PRK03918  291 KAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI-EERIKELEEKEERLEELKKKLKELEKRLEelEERHELYEEAKA 369
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  584 LQSELEEYQAQGRVLRLPCQNALSEELDGHGDGIEQDQEPGSGECNPLNMSI-EAELVIEQLKEQHHR-DLCHLRLELED 661
Cdd:PRK03918  370 KKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIkELKKAIEELKKAKGKcPVCGRELTEEH 449
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  662 KVRHYEK-QLDHTRVACEKEQVAMK-QKYEQGMRTLEKQISElQSEIADLQGQAAVLKEAhhkascrhEEEKKQLQMVFD 739
Cdd:PRK03918  450 RKELLEEyTAELKRIEKELKEIEEKeRKLRKELRELEKVLKK-ESELIKLKELAEQLKEL--------EEKLKKYNLEEL 520
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  740 EEKTQLQEELRlEHEQELKARLQQAEESFRQErEGLAQAAAWTEEKARSLTRDLEQSHQEqLLSLMEKHALEKEELRKEL 819
Cdd:PRK03918  521 EKKAEEYEKLK-EKLIKLKGEIKSLKKELEKL-EELKKKLAELEKKLDELEEELAELLKE-LEELGFESVEELEERLKEL 597
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  820 SEYHQR--ELQEGREEMETECNRRVS---QIEAQFQ--ADCEKVTERCEQTLQSLEGRYRQELKDLLDQHLEERSQWEFE 892
Cdd:PRK03918  598 EPFYNEylELKDAEKELEREEKELKKleeELDKAFEelAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAG 677
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 672056299  893 KDELTQECTEAQEQLEEVLQREKATALARSQEQETLEKTHK 933
Cdd:PRK03918  678 LRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEK 718
Filament pfam00038
Intermediate filament protein;
1544-1826 4.41e-03

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 41.44  E-value: 4.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1544 LQEENSILRNEITTLNEEDSISNLKLEELNGSQ-EELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQqldsenKELS 1622
Cdd:pfam00038   23 LEQQNKLLETKISELRQKKGAEPSRLYSLYEKEiEDLRRQLDTLTVERARLQLELDNLRLAAEDFRQKYE------DELN 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1623 QKNSQnKEELKTLNQRLAEMLCQKEDpgtctsekWEQENESLKEELDRYKVQTSTLVSSLEAELSEvklQTHIVEQENLL 1702
Cdd:pfam00038   97 LRTSA-ENDLVGLRKDLDEATLARVD--------LEAKIESLKEELAFLKKNHEEEVRELQAQVSD---TQVNVEMDAAR 164
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  1703 ----------LKDELERLKQLHRCPDLSDFQQKMcsilsynENLLKEKEVLSEELKSCADKLAESSL----LEHRIATIK 1768
Cdd:pfam00038  165 kldltsalaeIRAQYEEIAAKNREEAEEWYQSKL-------EELQQAAARNGDALRSAKEEITELRRtiqsLEIELQSLK 237
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 672056299  1769 EEREAWEEQSQDLKSQLALSQEKVQNledilknvnlQMAQIESDLQVTRQEKEALKQE 1826
Cdd:pfam00038  238 KQKASLERQLAETEERYELQLADYQE----------LISELEAELQETRQEMARQLRE 285
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
683-943 4.71e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 41.98  E-value: 4.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  683 AMKQKYEQgMRTLEKQISELQSEIADLQGQAAVLKEAHhkascrheEEKKQLQMVFDEEkTQLQEEL-RLEHEQELKARL 761
Cdd:COG0497   159 EYREAYRA-WRALKKELEELRADEAERARELDLLRFQL--------EELEAAALQPGEE-EELEEERrRLSNAEKLREAL 228
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  762 QQAEESFRQEreglaqaaawteekarsltrdlEQSHQEQLLSLMekHALEK-EELRKELSEYHQReLQEGREEMEtECNR 840
Cdd:COG0497   229 QEALEALSGG----------------------EGGALDLLGQAL--RALERlAEYDPSLAELAER-LESALIELE-EAAS 282
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  841 RVSQIEAQFQAD---CEKVTERCeQTLQSLEGRYRQELKDLLDQH------LEERSQWEFEKDELTQECTEAQEQLeevl 911
Cdd:COG0497   283 ELRRYLDSLEFDperLEEVEERL-ALLRRLARKYGVTVEELLAYAeelraeLAELENSDERLEELEAELAEAEAEL---- 357
                         250       260       270
                  ....*....|....*....|....*....|....
gi 672056299  912 qREKATAL--ARSQEQETLEKTHKERLAILSMER 943
Cdd:COG0497   358 -LEAAEKLsaARKKAAKKLEKAVTAELADLGMPN 390
GBP_C cd16269
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...
739-851 5.12e-03

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.


Pssm-ID: 293879 [Multi-domain]  Cd Length: 291  Bit Score: 41.02  E-value: 5.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299  739 DEEKTQLQEELRLEHEQELKARLQQAEESFRQEREGLAQAAAWTEEKarslTRDLEQSHQEQLLSLMEKHALEKEELRKE 818
Cdd:cd16269   181 AEAEAILQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQRELEQK----LEDQERSYEEHLRQLKEKMEEERENLLKE 256
                          90       100       110
                  ....*....|....*....|....*....|...
gi 672056299  819 LSEYHQRELQEGREEMETECNRRVSQIEAQFQA 851
Cdd:cd16269   257 QERALESKLKEQEALLEEGFKEQAELLQEEIRS 289
PRK01156 PRK01156
chromosome segregation protein; Provisional
1540-1830 6.67e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.43  E-value: 6.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1540 ESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKLKNQQLDSENK 1619
Cdd:PRK01156  160 EINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKS 239
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1620 ELSQKNSQnKEELKTLNQRLAEMLCQKEDPgtctsekwEQENESLKEELDRYKVQTSTLVSSLEAELSE-VKLQTHIVEQ 1698
Cdd:PRK01156  240 ALNELSSL-EDMKNRYESEIKTAESDLSME--------LEKNNYYKELEERHMKIINDPVYKNRNYINDyFKYKNDIENK 310
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1699 ENLL--LKDELERLKQLHRcpDLSDFQQkmcsilSYNENLLKEKEVlsEELKSCADKLAESSL--------LEHRIATIK 1768
Cdd:PRK01156  311 KQILsnIDAEINKYHAIIK--KLSVLQK------DYNDYIKKKSRY--DDLNNQILELEGYEMdynsylksIESLKKKIE 380
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672056299 1769 EEREAWEEQSQDLKSQLALSQEKVQNLEDILKNVNLQMAQIESDLQVTRQEKEALKQEVMSL 1830
Cdd:PRK01156  381 EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDEL 442
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1218-1710 8.10e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 8.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1218 DLKSQIIQLQEQLTVLRADCDRASERKRDLLFDISVLKKKLKMLERLPEASSKYKVLYEDAARENACLQEELRLMEMRY- 1296
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAl 392
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1297 ADSLDSNKELTAEVYRLQDEMKKMEEVTGTFLSLENSYDEVKLENEKLSALVLRLQGKMEEVLERAALQGDSYSLWEGPS 1376
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1377 ENLEVTSDEKMLELHQTEeectpevmSRHHIIEECRqetrccEQGSTQLLAGIKAHEIAWFRRKIETHQEKPSVQNRVIL 1456
Cdd:COG1196   473 ALLEAALAELLEELAEAA--------ARLLLLLEAE------ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1457 EESAALLGlqgthLQHEATIAELELEKQKLQELTRNLRERVTTLAKQKDAPSQGEEEEELKAVMHDLQITCGEMQRKVEL 1536
Cdd:COG1196   539 ALEAALAA-----ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1537 LRYESEKLQEENSIL-------RNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQKMVEKLKKQVSDLKL 1609
Cdd:COG1196   614 RYYVLGDTLLGRTLVaarleaaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1610 KNQQLDSENKELSQKNSQNKEELKTLNQRLAEMLCQKEdpgtctsekwEQENESLKEELDRYKVQTSTLVSSLEAELSEV 1689
Cdd:COG1196   694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE----------AEREELLEELLEEEELLEEEALEELPEPPDLE 763
                         490       500
                  ....*....|....*....|.
gi 672056299 1690 KLQTHIVEqenllLKDELERL 1710
Cdd:COG1196   764 ELERELER-----LEREIEAL 779
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
468-1055 8.40e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.31  E-value: 8.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   468 RQEREqiLQQVGKQRVELEQEIEKAKTEENYIRDRLALSLKENNRLENELLENAEKLAEYENLTSKL---QRSLENVLAE 544
Cdd:pfam01576    2 RQEEE--MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLaarKQELEEILHE 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   545 KFGDLDPssaefflQEERLAQMRNEYEQqcrlLQDQVDELQSELEEYQAQGRVLRLP--CQNALSEELDGHGDGIEQDQE 622
Cdd:pfam01576   80 LESRLEE-------EEERSQQLQNEKKK----MQQHIQDLEEQLDEEEAARQKLQLEkvTTEAKIKKLEEDILLLEDQNS 148
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   623 PGSGECNPLNMSIEAELVIEQLKEQHHRDLCHLRLELEDKVRHYEKQLdhtrvaceKEQVAMKQKYEQGMRTLEKQISEL 702
Cdd:pfam01576  149 KLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERL--------KKEEKGRQELEKAKRKLEGESTDL 220
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   703 QSEIADLQGQAAVLKEAHHKascrHEEEKKQLQMVFDEE---KTQLQEELRleheqELKARLQQAEESFRQEREGLAQAa 779
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAK----KEEELQAALARLEEEtaqKNNALKKIR-----ELEAQISELQEDLESERAARNKA- 290
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   780 awteEKARsltRDLEQshqeqllslmEKHALEKEELRKELSEYHQRELQEGREEMETECNRRVsqieaqfqadcEKVTER 859
Cdd:pfam01576  291 ----EKQR---RDLGE----------ELEALKTELEDTLDTTAAQQELRSKREQEVTELKKAL-----------EEETRS 342
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   860 CEQTLQSLEGRYRQ---ELKDLLDQHLEERSQWEFEKDELTQECTEAQEQLEEVLQ--------REKATA-----LARSQ 923
Cdd:pfam01576  343 HEAQLQEMRQKHTQaleELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQakqdsehkRKKLEGqlqelQARLS 422
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299   924 EQETLEKTHKERLAILSMEREQLLQDLKDLQNTSERQHSLLSDQMLELKRSQERELREPEHVLC-----------QTGVS 992
Cdd:pfam01576  423 ESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNlstrlrqledeRNSLQ 502
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672056299   993 EQLGSQQLARLQVEHE------------QERREMAGKIAALESAHR---VSCERADQEKAEMSAEIRRLQSTVKDLQQ 1055
Cdd:pfam01576  503 EQLEEEEEAKRNVERQlstlqaqlsdmkKKLEEDAGTLEALEEGKKrlqRELEALTQQLEEKAAAYDKLEKTKNRLQQ 580
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1309-1830 9.15e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.22  E-value: 9.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1309 EVYRLQDEMKKMEEVTGTFLSLENSYDEVKLENEKLSALVLRLQGKMEEVLERAALQGD-SYSLWEGP--SENLEVTSDE 1385
Cdd:COG5022   763 RYLQALKRIKKIQVIQHGFRLRRLVDYELKWRLFIKLQPLLSLLGSRKEYRSYLACIIKlQKTIKREKklRETEEVEFSL 842
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1386 KMLELHQTEEEctpEVMSRHHIIEECRQETRccEQGSTQLLagiKAHeiawfRRKIETHQEKPSVQNRVILEESAALLGL 1465
Cdd:COG5022   843 KAEVLIQKFGR---SLKAKKRFSLLKKETIY--LQSAQRVE---LAE-----RQLQELKIDVKSISSLKLVNLELESEII 909
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1466 QGTHLQHEATIAELELEKQKLQELTRNLRERVTTLAKQKDAPSQGEEEE--ELKAVMHDLQITCGEMQRKVELLRYESEK 1543
Cdd:COG5022   910 ELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKlhEVESKLKETSEEYEDLLKKSTILVREGNK 989
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1544 LQEENSILRNEITTLNEE---DSISNLKLEELNGSQEELWQKIETIEQEKASIQKMvEKLKKQVSDLKLKNQQLDSENKE 1620
Cdd:COG5022   990 ANSELKNFKKELAELSKQygaLQESTKQLKELPVEVAELQSASKIISSESTELSIL-KPLQKLKGLLLLENNQLQARYKA 1068
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1621 LSQKNSQNKEELKTLNQRLAemlcqkedpgtcTSEKWEQENESLKEELDRYKVQTSTLVSSLEAELSEVKLQTHIVE--- 1697
Cdd:COG5022  1069 LKLRRENSLLDDKQLYQLES------------TENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKfls 1136
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672056299 1698 QENLLLKDELERLKQLHRCPDLSDFQQKMCSILSYN-ENLLKEKEVLSEELKSCADKLAESSLLEHRIATIKEEREAWEE 1776
Cdd:COG5022  1137 QLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPpFAALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALFSKIFSG 1216
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672056299 1777 QSQDLKSQLALSQEKV-----------QNLEDILKN--------VNLQMAQIESDLQVTRQEKEALKQEVMSL 1830
Cdd:COG5022  1217 WPRGDKLKKLISEGWVpteystslkgfNNLNKKFDTpasmsnekLLSLLNSIDNLLSSYKLEEEVLPATINSL 1289
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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