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Conserved domains on  [gi|767955214|ref|XP_011516310|]
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excitatory amino acid transporter 3 isoform X2 [Homo sapiens]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
34-471 5.22e-111

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 335.93  E-value: 5.22e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  34 GITTGVLVREHSNLstlekfYFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILG 112
Cdd:COG1301   16 GILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALVIG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 113 IVLVVSIKPGVTqkVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQAcfqqyktkreevkppsdpemnMTEesftavmt 192
Cdd:COG1301   90 LVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA---------------------FAE-------- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 193 taisknktkeykivgmysdgINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGK 272
Cdd:COG1301  139 --------------------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAAT 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 273 IIEVeDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQ 352
Cdd:COG1301  199 VAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLG 277

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 353 VDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLP 432
Cdd:COG1301  278 VSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLP 357

                        410       420       430
                 ....*....|....*....|....*....|....*....
gi 767955214 433 AEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 471
Cdd:COG1301  358 LEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
34-471 5.22e-111

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 335.93  E-value: 5.22e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  34 GITTGVLVREHSNLstlekfYFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILG 112
Cdd:COG1301   16 GILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALVIG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 113 IVLVVSIKPGVTqkVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQAcfqqyktkreevkppsdpemnMTEesftavmt 192
Cdd:COG1301   90 LVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA---------------------FAE-------- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 193 taisknktkeykivgmysdgINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGK 272
Cdd:COG1301  139 --------------------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAAT 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 273 IIEVeDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQ 352
Cdd:COG1301  199 VAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLG 277

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 353 VDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLP 432
Cdd:COG1301  278 VSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLP 357

                        410       420       430
                 ....*....|....*....|....*....|....*....
gi 767955214 433 AEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 471
Cdd:COG1301  358 LEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
SDF pfam00375
Sodium:dicarboxylate symporter family;
54-468 7.92e-108

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 326.79  E-value: 7.92e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214   54 YFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIAR 132
Cdd:pfam00375  25 WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLALIAASL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  133 TGStpEVSTVDAMLDLIRNMFPENLVQACFQQyktkreevkppsdpemnmteesftavmttaisknktkeykivgmysdg 212
Cdd:pfam00375 105 KEA--KAAEAPSLLDFILNIIPSNIFEALAEG------------------------------------------------ 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  213 iNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEvEDWEIFRKLGLYMATV 292
Cdd:pfam00375 135 -NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILSSLAKFLLVV 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  293 LTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDG 372
Cdd:pfam00375 213 YLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDG 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  373 TALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTM 452
Cdd:pfam00375 293 TAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTA 372

                         410
                  ....*....|....*.
gi 767955214  453 VNVLGDAFGTGIVEKL 468
Cdd:pfam00375 373 VNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 91-467 2.80e-34

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 134.26  E-value: 2.80e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  91 GKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVtqkvgeiartGSTPEVSTVDAmldlirnmfpenlvqACFQQYKTKRE 170
Cdd:PRK01663  71 GRVGGKALLYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA---------------KAVAQYAAQAH 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 171 EvkppsdpemnmteESFTAVMTTAISKNktkeykIVGMYSDGiNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDAT 250
Cdd:PRK01663 126 E-------------QGTVDFLMDIIPTT------VVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVL 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 251 MKIVQIIMCYMPLGILFLIA--------GKIIevedweifrKLGLYMATVLTGLAIHSIVILPLIyfivVRKNPF---RF 319
Cdd:PRK01663 186 FGIVNMIMKLAPIGAFGAMAftigkygvGSLV---------QLGQLIGCFYITCILFVFVVLGAI----ARLTGFsifKF 252

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 320 AMGMAQALLTALMISSSSATLPVTFRcAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIIT 399
Cdd:PRK01663 253 IRYIKEELLIVLGTSSSESALPRMME-KMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQIT 331

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767955214 400 ISITATSASIGAAGVPQAGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 467
Cdd:PRK01663 332 LLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGVATVVVAK 400
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
34-471 5.22e-111

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 335.93  E-value: 5.22e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  34 GITTGVLVREHSNLstlekfYFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILG 112
Cdd:COG1301   16 GILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALVIG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 113 IVLVVSIKPGVTqkVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQAcfqqyktkreevkppsdpemnMTEesftavmt 192
Cdd:COG1301   90 LVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA---------------------FAE-------- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 193 taisknktkeykivgmysdgINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGK 272
Cdd:COG1301  139 --------------------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAAT 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 273 IIEVeDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQ 352
Cdd:COG1301  199 VAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLG 277

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 353 VDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLP 432
Cdd:COG1301  278 VSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLP 357

                        410       420       430
                 ....*....|....*....|....*....|....*....
gi 767955214 433 AEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 471
Cdd:COG1301  358 LEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
SDF pfam00375
Sodium:dicarboxylate symporter family;
54-468 7.92e-108

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 326.79  E-value: 7.92e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214   54 YFAFPGEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIAR 132
Cdd:pfam00375  25 WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLALIAASL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  133 TGStpEVSTVDAMLDLIRNMFPENLVQACFQQyktkreevkppsdpemnmteesftavmttaisknktkeykivgmysdg 212
Cdd:pfam00375 105 KEA--KAAEAPSLLDFILNIIPSNIFEALAEG------------------------------------------------ 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  213 iNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEvEDWEIFRKLGLYMATV 292
Cdd:pfam00375 135 -NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILSSLAKFLLVV 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  293 LTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDG 372
Cdd:pfam00375 213 YLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDG 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  373 TALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTM 452
Cdd:pfam00375 293 TAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTA 372

                         410
                  ....*....|....*.
gi 767955214  453 VNVLGDAFGTGIVEKL 468
Cdd:pfam00375 373 VNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 91-467 2.80e-34

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 134.26  E-value: 2.80e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  91 GKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVtqkvgeiartGSTPEVSTVDAmldlirnmfpenlvqACFQQYKTKRE 170
Cdd:PRK01663  71 GRVGGKALLYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA---------------KAVAQYAAQAH 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 171 EvkppsdpemnmteESFTAVMTTAISKNktkeykIVGMYSDGiNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDAT 250
Cdd:PRK01663 126 E-------------QGTVDFLMDIIPTT------VVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVL 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 251 MKIVQIIMCYMPLGILFLIA--------GKIIevedweifrKLGLYMATVLTGLAIHSIVILPLIyfivVRKNPF---RF 319
Cdd:PRK01663 186 FGIVNMIMKLAPIGAFGAMAftigkygvGSLV---------QLGQLIGCFYITCILFVFVVLGAI----ARLTGFsifKF 252

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 320 AMGMAQALLTALMISSSSATLPVTFRcAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIIT 399
Cdd:PRK01663 253 IRYIKEELLIVLGTSSSESALPRMME-KMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQIT 331

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767955214 400 ISITATSASIGAAGVPQAGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 467
Cdd:PRK01663 332 LLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGVATVVVAK 400
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 34-467 3.98e-34

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 133.73  E-value: 3.98e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  34 GITTGVLVREHSNLSTLEKFYFAFP-GEILMRMLKLIILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTLIAVIL 111
Cdd:PRK11283  19 GILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITTVAIIL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 112 GIVLVVSIKPGVTQKVGEIArtgstpevsTVDamldlirnmfpenlvqacFQQYKTKREEVKPPSdpemnmteESFTAVM 191
Cdd:PRK11283  99 GITLANVFQPGAGIDMSQLA---------TVD------------------ISKYQSTTEEVQSHS--------HGLMGTI 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 192 TTAISKNktkeykIVGMYSDGiNVLGLIVFCLVFGLVIGKMGEK-GQILVDFFNALSDATMKIVQIIMCYMPLGILFLIA 270
Cdd:PRK11283 144 LSLIPTN------IFASMAKG-EMLPIIFFSVLFGLGLSSLPAThREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIA 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 271 gkiIEVEDWEIFRKLGLYMATVLTGLAI--HSIVILPLIYFIVvRKNPFRFAMGMAQALLTALMISSSSATLPvtfRCAE 348
Cdd:PRK11283 217 ---VTVANFGFASLWPLAKLVLLVYFAIlfFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLP---RIIE 289

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 349 --ENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVL 426
Cdd:PRK11283 290 kmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATL 369

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|.
gi 767955214 427 SAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 467
Cdd:PRK11283 370 GSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAK 410
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 91-465 1.73e-32

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 129.02  E-value: 1.73e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214  91 GKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQkvgeiartgstpevstvdamldlirNMFPENLVQACFQQYKTKRE 170
Cdd:PRK13027  70 GRVGLKAVIYFEVMTTIALVIGLVLAYLTGPGVGM-------------------------NIDLRSLDAASLAGYAKNAQ 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 171 EVKPPSDPEMNMTEESFtavmttaisknktkeykiVGMYSDGiNVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDAT 250
Cdd:PRK13027 125 SLKGTAGFLLKLIPTTA------------------VDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVL 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 251 MKIVQIIMCYMPLGILFLIAgkiIEVEDWEI--FRKLGLYMATVLTGLAIHSIVILPLiyfiVVRKNPFR---FAMGMAQ 325
Cdd:PRK13027 186 FRIMGFIIKLAPLGVLGAIA---FTTGKYGVgsLKQLGMLVAVFYLTCFVFVVVVLGA----VMRLAGFSvfkLIRYLRE 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 326 ALLTALMISSSSATLPVTFRcAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITAT 405
Cdd:PRK13027 259 ELLIVLGTASSDAVLPQVMR-KLEHMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSL 337

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767955214 406 SASIGAAGVPQAGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIV 465
Cdd:PRK13027 338 VTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 214-472 8.31e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 66.23  E-value: 8.31e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 214 NVLGLIVFCLVFGLVigkMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAgKIIEVEDWEIFRKLGLYMATVL 293
Cdd:PRK14695  60 NYIGILSWAVIFGIA---MREASKNSKELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLANYGILLVLLV 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 294 TGLAIHSIVILPLIYFIVVRKNPFRFAMG-MAQALLTALMISSSSATLPVTFRCAEENNqVDKRITRFVLPVGATINMDG 372
Cdd:PRK14695 136 TTMLFVAPVVNPLIAFFFMRRNPYPLVWNcLRVSGVTAFFTRSSATNIPVNMKLCHDLG-LNPDTYSVSIPLGSTINMAG 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 373 TALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLL----DR 448
Cdd:PRK14695 215 VAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqDS 294

                        250       260
                 ....*....|....*....|....
gi 767955214 449 FRTMVNVLGDAFGTGIVEKLSKKE 472
Cdd:PRK14695 295 CETALNSSTDVLFTAVAEYAATRK 318
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 241-414 6.09e-11

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 64.11  E-value: 6.09e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 241 DFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEvEDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFA 320
Cdd:PRK13628 170 NVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAE-TGFSALAGYAQLLAVLVGCMLFVALVVNPLIVFWKIRRNPYPLV 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 321 MG-MAQALLTALMISSSSATLPVTFRCAEENNqVDKRITRFVLPVGATINMDGTALYEAV---AAVFIaqlndldLGI-- 394
Cdd:PRK13628 249 FTcLRESGVTAFFTRSSAANIPVNMALCEKLG-LDEDTYSVSIPLGATINMAGAAITITVltlAAVHT-------LGIpv 320

                        170       180
                 ....*....|....*....|..
gi 767955214 395 --GQIITISITATSASIGAAGV 414
Cdd:PRK13628 321 dlPTALLLSVVAAISACGASGV 342
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
241-415 1.30e-10

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 63.27  E-value: 1.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 241 DFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVeDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFA 320
Cdd:COG3633  169 TVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATT-GFSALLGYAHLLAVLVGCMLFVALVVNPLIVFLKIRRNPYPLV 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767955214 321 -MGMAQALLTALMISSSSATLPVTFRCAEENNqVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIIT 399
Cdd:COG3633  248 fTCLRESGITAFFTRSSAANIPVNMALCEKLG-LDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEVDLPTALL 326

                        170
                 ....*....|....*.
gi 767955214 400 ISITATSASIGAAGVP 415
Cdd:COG3633  327 LSVVAAVSACGASGVA 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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