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Conserved domains on  [gi|767979714|ref|XP_011534731|]
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NADP-dependent oxidoreductase domain-containing protein 1 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ProC super family cl33843
Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; ...
 30-99 3.73e-07

Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Pyrroline-5-carboxylate reductase is part of the Pathway/BioSystem: Proline biosynthesis


The actual alignment was detected with superfamily member COG0345:

Pssm-ID: 440114 [Multi-domain]  Cd Length: 267  Bit Score: 50.06  E-value: 3.73e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767979714  30 QKLGIKCFYHNADLVSWADVIFLCCLPSQLPNICVEIYTSLEKASIVYSFVAAIPLPRL-KLLLNHTNILR 99
Cdd:COG0345   46 ERYGVRVTTDNAEAAAQADVVVLAVKPQDLAEVLEELAPLLDPDKLVISIAAGVTLATLeEALGGGAPVVR 116
 
Name Accession Description Interval E-value
ProC COG0345
Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; ...
 30-99 3.73e-07

Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Pyrroline-5-carboxylate reductase is part of the Pathway/BioSystem: Proline biosynthesis


Pssm-ID: 440114 [Multi-domain]  Cd Length: 267  Bit Score: 50.06  E-value: 3.73e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767979714  30 QKLGIKCFYHNADLVSWADVIFLCCLPSQLPNICVEIYTSLEKASIVYSFVAAIPLPRL-KLLLNHTNILR 99
Cdd:COG0345   46 ERYGVRVTTDNAEAAAQADVVVLAVKPQDLAEVLEELAPLLDPDKLVISIAAGVTLATLeEALGGGAPVVR 116
PRK11880 PRK11880
pyrroline-5-carboxylate reductase; Reviewed
 29-99 7.47e-07

pyrroline-5-carboxylate reductase; Reviewed


Pssm-ID: 237008 [Multi-domain]  Cd Length: 267  Bit Score: 48.99  E-value: 7.47e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767979714  29 LQKLGIKCFYHNADLVSWADVIFLCCLPSQLPNICVEIYTSLEKasIVYSFVAAIPLPRLKLLLN-HTNILR 99
Cdd:PRK11880  45 AEEYGVRAATDNQEAAQEADVVVLAVKPQVMEEVLSELKGQLDK--LVVSIAAGVTLARLERLLGaDLPVVR 114
 
Name Accession Description Interval E-value
ProC COG0345
Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; ...
 30-99 3.73e-07

Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Pyrroline-5-carboxylate reductase is part of the Pathway/BioSystem: Proline biosynthesis


Pssm-ID: 440114 [Multi-domain]  Cd Length: 267  Bit Score: 50.06  E-value: 3.73e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767979714  30 QKLGIKCFYHNADLVSWADVIFLCCLPSQLPNICVEIYTSLEKASIVYSFVAAIPLPRL-KLLLNHTNILR 99
Cdd:COG0345   46 ERYGVRVTTDNAEAAAQADVVVLAVKPQDLAEVLEELAPLLDPDKLVISIAAGVTLATLeEALGGGAPVVR 116
PRK11880 PRK11880
pyrroline-5-carboxylate reductase; Reviewed
 29-99 7.47e-07

pyrroline-5-carboxylate reductase; Reviewed


Pssm-ID: 237008 [Multi-domain]  Cd Length: 267  Bit Score: 48.99  E-value: 7.47e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767979714  29 LQKLGIKCFYHNADLVSWADVIFLCCLPSQLPNICVEIYTSLEKasIVYSFVAAIPLPRLKLLLN-HTNILR 99
Cdd:PRK11880  45 AEEYGVRAATDNQEAAQEADVVVLAVKPQVMEEVLSELKGQLDK--LVVSIAAGVTLARLERLLGaDLPVVR 114
PLN02688 PLN02688
pyrroline-5-carboxylate reductase
 29-99 7.24e-05

pyrroline-5-carboxylate reductase


Pssm-ID: 178291 [Multi-domain]  Cd Length: 266  Bit Score: 43.02  E-value: 7.24e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767979714  29 LQKLGIKCFYHNADLVSWADVIFLCCLPSQLPNICVEIYTSLEKASIVYSFVAAIPLPRLKLLLNHTNILR 99
Cdd:PLN02688  44 FQSLGVKTAASNTEVVKSSDVIILAVKPQVVKDVLTELRPLLSKDKLLVSVAAGITLADLQEWAGGRRVVR 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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