|
Name |
Accession |
Description |
Interval |
E-value |
| CEP209_CC5 |
pfam16574 |
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ... |
1576-1703 |
1.97e-45 |
|
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.
Pssm-ID: 465184 [Multi-domain] Cd Length: 128 Bit Score: 160.63 E-value: 1.97e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1576 TMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNRELVKD 1655
Cdd:pfam16574 1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 767975378 1656 KEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLER 1703
Cdd:pfam16574 81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1369-2176 |
6.66e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 81.26 E-value: 6.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1369 HLRTSLKQMEERNFELETKFAELTKinldaqkvEQMLRDELADSVSKAVSDADRqriLELEKNEMELKVEV------SKL 1442
Cdd:TIGR02168 226 ELALLVLRLEELREELEELQEELKE--------AEEELEELTAELQELEEKLEE---LRLEVSELEEEIEElqkelyALA 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1443 REISDIaRRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKlhqhnvSLQLSEATALGKLESITSKLQKMEAYN 1522
Cdd:TIGR02168 295 NEISRL-EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA------ELEEKLEELKEELESLEAELEELEAEL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1523 LRLEQKLDEKEQALYYARlegrNRAKHLRQTIQSLRRQFsgalplaQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNME 1602
Cdd:TIGR02168 368 EELESRLEELEEQLETLR----SKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1603 NKTLEMELKLKGLEELISTLKDTkgAQKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQ 1682
Cdd:TIGR02168 437 ELQAELEELEEELEELQEELERL--EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1683 QNKFHEERQMAWDQREVDLERQLDIF----DRQQNEILNAAQKFEEATGSIPDPSLPLPNQLE---IALRKIKENIRIIL 1755
Cdd:TIGR02168 515 QSGLSGILGVLSELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPldsIKGTEIQGNDREIL 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1756 ETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELR--LRLPATAEREKLIAELGRKEMEPKSHHTLKIAhQTIANMQ 1833
Cdd:TIGR02168 595 KNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDnaLELAKKLRPGYRIVTLDGDLVRPGGVITGGSA-KTNSSIL 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1834 ARLNQKEEVLKKYQRLLEKAREEQREIVkkheedlhilhhRLELQADSSLNKFKQTAWDLMKQSPTPVPTNKHFIRLAEM 1913
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALA------------ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1914 EQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEfeniklqlqenHEDEVKKVKAEVEDLKYLLDQSQKESQCLKS 1993
Cdd:TIGR02168 742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE-----------AEAEIEELEAQIEQLKEELKALREALDELRA 810
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1994 ELQAQKEANSRAptttmRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDrhtre 2073
Cdd:TIGR02168 811 ELTLLNEEAANL-----RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN----- 880
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2074 lktQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG--K 2151
Cdd:TIGR02168 881 ---ERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEeaE 957
|
810 820
....*....|....*....|....*
gi 767975378 2152 PLTDNKQSLIEELQRKVKKLENQLE 2176
Cdd:TIGR02168 958 ALENKIEDDEEEARRRLKRLENKIK 982
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
843-1562 |
1.41e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 1.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 843 QINSLENLIEQLRRELVFLRSQNEIIAQEFLIKEAECRNADIELEHHRSQAEQnefLSRELIEKERDLERSRTVIAKFQN 922
Cdd:TIGR02168 226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE---LEEEIEELQKELYALANEISRLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 923 KLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIfdaslHLKAQVDQLTGRNEEL 1002
Cdd:TIGR02168 303 QKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE-----ELEAELEELESRLEEL 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1003 RQELRESRKEAINYSQQLAKANLKIDHLEKEtslLRQSEGSNVVFKGIDLPDGIAPSSASIINSQneylihllQELENKE 1082
Cdd:TIGR02168 378 EEQLETLRSKVAQLELQIASLNNEIERLEAR---LERLEDRRERLQQEIEELLKKLEEAELKELQ--------AELEELE 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1083 KKLKNLEDSLEDYNRkfavirhqqsllykeylsEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEM 1162
Cdd:TIGR02168 447 EELEELQEELERLEE------------------ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1163 KKILAENSRK-------ITVLQVNEK---------SLIRQYTTLVELERQLR-----KENEKQK-----------NELLS 1210
Cdd:TIGR02168 509 KALLKNQSGLsgilgvlSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKaiaflKQNELGRvtflpldsikgTEIQG 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1211 MEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLS----ELELANKQYNELTAKYRDI-----------------LQK 1269
Cdd:TIGR02168 589 NDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvdDLDNALELAKKLRPGYRIVtldgdlvrpggvitggsAKT 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1270 DNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKLGNEssmdkakksitnsdivsISKKITML 1349
Cdd:TIGR02168 669 NSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-----------------LSRQISAL 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1350 EMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKiNLDAQKVEQMLRDELADSVSKAVSdADRQRILELE 1429
Cdd:TIGR02168 732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAEAEIEELEAQIEQLKEELK-ALREALDELR 809
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1430 KNEMELKVEVSKLRE-----ISDIARRQVEILNAQQQSRDK--EVESLRMQLLDYQAQSDEKSLIAKLHQHNV-SLQLSE 1501
Cdd:TIGR02168 810 AELTLLNEEAANLRErleslERRIAATERRLEDLEEQIEELseDIESLAAEIEELEELIEELESELEALLNERaSLEEAL 889
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767975378 1502 ATALGKLESITSKLQKMEAYNLRLEQKLDEKEQAL--YYARLEGrnrakhLRQTIQSLRRQFS 1562
Cdd:TIGR02168 890 ALLRSELEELSEELRELESKRSELRRELEELREKLaqLELRLEG------LEVRIDNLQERLS 946
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1250-2175 |
1.39e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.47 E-value: 1.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1250 ELANKQYNELTAKYRDI--LQKDNM---LVQRTSNLEHLECENISLKE---QVESINKELEITKEKLHTIEQAWEQET-K 1320
Cdd:PTZ00121 1031 ELTEYGNNDDVLKEKDIidEDIDGNhegKAEAKAHVGQDEGLKPSYKDfdfDAKEDNRADEATEEAFGKAEEAKKTETgK 1110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1321 LGNESSMDKAKKSItnSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTS-LKQMEERNFELETKFAELTKINLDAQ 1399
Cdd:PTZ00121 1111 AEEARKAEEAKKKA--EDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEdARKAEEARKAEDAKKAEAARKAEEVR 1188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1400 KVEQMLRDELADSVSKAVSDADRQRILELEKNEMELKVEvsKLREISDIARRQVEilnAQQQSRDKEVESLRMQLLDYQA 1479
Cdd:PTZ00121 1189 KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAE--AVKKAEEAKKDAEE---AKKAEEERNNEEIRKFEEARMA 1263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1480 QSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRR 1559
Cdd:PTZ00121 1264 HFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKK 1343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1560 --QFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGA---QKVINW 1634
Cdd:PTZ00121 1344 aaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAaakKKADEA 1423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1635 HMKIEELR-LQELKLNRELVKDKEEIKYLnniiSEYERTISSLEEEIVQQNKFHEERQMAWDQREVD-LERQLDIFDRQQ 1712
Cdd:PTZ00121 1424 KKKAEEKKkADEAKKKAEEAKKADEAKKK----AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADeAKKKAEEAKKKA 1499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1713 NEilnaAQKFEEATGSIPDPSLPLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINEL 1792
Cdd:PTZ00121 1500 DE----AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED 1575
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1793 RLRLPATAE-----REKLIAELGRKEMEPKSHHTLKIAHQTIANMQA-RLNQKEEVLKKYQRLLEKAREEQR--EIVKKH 1864
Cdd:PTZ00121 1576 KNMALRKAEeakkaEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAeELKKAEEEKKKVEQLKKKEAEEKKkaEELKKA 1655
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1865 EEDLHILHHRLELQADSSLNKFKQtawdlmkqsptpvptnkhfIRLAEMEQTVAEQddslssllvklkKVSQDLERQREI 1944
Cdd:PTZ00121 1656 EEENKIKAAEEAKKAEEDKKKAEE-------------------AKKAEEDEKKAAE------------ALKKEAEEAKKA 1704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1945 TELKVKEFENIKLQLQENHEDEVKKVKaeVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALK 2024
Cdd:PTZ00121 1705 EELKKKEAEEKKKAEELKKAEEENKIK--AEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2025 E--KQQKALSRALLELRAEMTAAAEERIISATSQKEAHLN-VQQIVDRHTRELkTQVEDLNENLLKLKEALKTSKNRENS 2101
Cdd:PTZ00121 1783 EelDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINdSKEMEDSAIKEV-ADSKNMQLEEADAFEKHKFNKNNENG 1861
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767975378 2102 LTDNLN-DLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQL 2175
Cdd:PTZ00121 1862 EDGNKEaDFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEI 1936
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1927-2220 |
8.10e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.11 E-value: 8.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1927 LLVKLKKVSQDLERQREITELKVKEFENIKLQLQEnHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQaqKEANSRAP 2006
Cdd:COG1196 230 LLLKLRELEAELEELEAELEELEAELEELEAELAE-LEAELEELRLELEELELELEEAQAEEYELLAELA--RLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2007 TTTMRN----LVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRhTRELKTQVEDLN 2082
Cdd:COG1196 307 LEERRReleeRLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE-LAEAEEELEELA 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2083 ENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQgkpltdNKQSLIE 2162
Cdd:COG1196 386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA------ELEEEEE 459
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 767975378 2163 ELQRKVKKLENQLEGKVEEV-DLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKE 2220
Cdd:COG1196 460 ALLELLAELLEEAALLEAALaELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
866-1673 |
1.42e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 60.54 E-value: 1.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 866 EIIAQEFLIKEAECRNADIELEHH-----RSQAEQNEFLSRELIEKERDlERSRTVIAKFQNKLKELVEENKQLEEGMKE 940
Cdd:PTZ00121 1034 EYGNNDDVLKEKDIIDEDIDGNHEgkaeaKAHVGQDEGLKPSYKDFDFD-AKEDNRADEATEEAFGKAEEAKKTETGKAE 1112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 941 ILQAIKE-MQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQ 1019
Cdd:PTZ00121 1113 EARKAEEaKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEE 1192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1020 LAKAN--LKIDHLEKETSLLRQSEgsnvVFKGIDLPDGIAPSSASIINSQNEYlIHLLQELENKEKKLKNLEDSLEDYNR 1097
Cdd:PTZ00121 1193 LRKAEdaRKAEAARKAEEERKAEE----ARKAEDAKKAEAVKKAEEAKKDAEE-AKKAEEERNNEEIRKFEEARMAHFAR 1267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1098 KFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLED--QVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITV 1175
Cdd:PTZ00121 1268 RQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEakKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEA 1347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1176 LQVNEKSLIRQYTTLVELER--QLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVvdnsvslselELAN 1253
Cdd:PTZ00121 1348 AKAEAEAAADEAEAAEEKAEaaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKA----------AAAK 1417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1254 KQYNELTAKYRDILQKDnmlvqrtsnlehleceniSLKEQVESINKELEItKEKLHTIEQAWEQETKLGNESSMDKAKKS 1333
Cdd:PTZ00121 1418 KKADEAKKKAEEKKKAD------------------EAKKKAEEAKKADEA-KKKAEEAKKAEEAKKKAEEAKKADEAKKK 1478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1334 ITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSlkqmEERNFELETKFAELTKINLDAQKVEQMLRdelADSV 1413
Cdd:PTZ00121 1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA----EEAKKADEAKKAEEAKKADEAKKAEEKKK---ADEL 1551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1414 SKAVsdadrqrilELEKNEMELKVE-VSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQ 1492
Cdd:PTZ00121 1552 KKAE---------ELKKAEEKKKAEeAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1493 HNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEK 1572
Cdd:PTZ00121 1623 EELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1573 FSKTMIQLQNDKLKIMQEMKNSQQEHRNM--ENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNR 1650
Cdd:PTZ00121 1703 KAEELKKKEAEEKKKAEELKKAEEENKIKaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782
|
810 820
....*....|....*....|...
gi 767975378 1651 ELVKDKEEIKYLnniisEYERTI 1673
Cdd:PTZ00121 1783 EELDEEDEKRRM-----EVDKKI 1800
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
243-563 |
1.91e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.00 E-value: 1.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 243 LEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDpimvAVNAKVEEWKLILSSKDD 322
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEE----KLKERLEELEEDLSSLEQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 323 EIIEYQQMLHNLREKLknAQLDADKSNVMALQQGIQ--ERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGAST 400
Cdd:TIGR02169 752 EIENVKSELKELEARI--EELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 401 LSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDRE-- 478
Cdd:TIGR02169 830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEle 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 479 --IEILTKEINKLELKISDFLDENEALRERVGL---EPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEE---RL 550
Cdd:TIGR02169 910 aqIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVlkrLD 989
|
330
....*....|...
gi 767975378 551 DLKKKIRQMAQER 563
Cdd:TIGR02169 990 ELKEKRAKLEEER 1002
|
|
| DUF1633 |
pfam07794 |
Protein of unknown function (DUF1633); This family contains sequences derived from a group of ... |
2052-2228 |
2.25e-07 |
|
Protein of unknown function (DUF1633); This family contains sequences derived from a group of hypothetical proteins expressed by Arabidopsis thaliana. These sequences are highly similar and the region concerned is about 100 residues long.
Pssm-ID: 116408 [Multi-domain] Cd Length: 698 Bit Score: 56.43 E-value: 2.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2052 SATSQKEAHLNVQQivdrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQ----KKQKAYNKILRek 2127
Cdd:pfam07794 458 RAIREEDPHLGADQ-----DREVRFGAEGIVPGIERLKIELSTSKDLEKGYAEKIGFMEMEFGgleaDKQMARNQIHR-- 530
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2128 eeIDQENDELKRQIKRLTSGLQG--KPLTDNK-------QSLIEELQRK--VKKLENQLEGKVEEVDLK-PMKEKNAKEE 2195
Cdd:pfam07794 531 --LEEKKDELSKKVLDLTSIAQGakKAVHDAKvelaaayLKLLAGIKDKwvAKKEFTVLEGQAAEVESNlALIDQITKAA 608
|
170 180 190
....*....|....*....|....*....|...
gi 767975378 2196 LIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTK 2228
Cdd:pfam07794 609 IDLTLEKPRFQAEIDDLEARCKLKEVSDFTLSK 641
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
837-1214 |
1.59e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.79 E-value: 1.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 837 AQSKLSQ----INSLENLIEQLRRELVFLRSQNEIiAQEFLIKEAECRNADIELehhrsqaeqnefLSRELIEKERDLER 912
Cdd:COG1196 177 AERKLEAteenLERLEDILGELERQLEPLERQAEK-AERYRELKEELKELEAEL------------LLLKLRELEAELEE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 913 SRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIEsknaegifdaslHLKAQV 992
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------------RLEERR 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 993 DQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSegsnvvfkgidlpdgiapssasiinsqneyLI 1072
Cdd:COG1196 312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE------------------------------LA 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1073 HLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKEtwktESKTIKEEKRKLEDQVQQDAIKVKEYNNLL 1152
Cdd:COG1196 362 EAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE----AEEALLERLERLEEELEELEEALAELEEEE 437
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767975378 1153 NALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAE 1214
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
21-563 |
8.27e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.48 E-value: 8.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 21 QEELADNLLISLSKVEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFEnQLKTKVMKLENELEM 100
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE-EAQAEEYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 101 AQQsaggrDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDI 180
Cdd:COG1196 300 LEQ-----DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 181 IDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRM 260
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 261 KAIVHQTDNVIDQLKKENDHYQLQVQELTDLL---KSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEyqQMLHNLREK 337
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELLEELaeaAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA--GAVAVLIGV 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 338 LKNAQLDADKSNVMALQQGIQERDSQIKMLteqveqytkemekntciIEDLKnelQRNKGASTLSQQTHMKIQSTLDILK 417
Cdd:COG1196 533 EAAYEAALEAALAAALQNIVVEDDEVAAAA-----------------IEYLK---AAKAGRATFLPLDKIRARAALAAAL 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 418 EKTKEAERTAELAEadarekdkELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEILTKEINKLELKISDFL 497
Cdd:COG1196 593 ARGAIGAAVDLVAS--------DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975378 498 DENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQER 563
Cdd:COG1196 665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
93-374 |
1.96e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 50.32 E-value: 1.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 93 KLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKK 172
Cdd:COG1196 217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 173 NEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEK 252
Cdd:COG1196 297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 253 MTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDL---LKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQ 329
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERlerLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 767975378 330 MLHNLREKLKNA--QLDADKSNVMALQQGIQERDSQIKMLTEQVEQY 374
Cdd:COG1196 457 EEEALLELLAELleEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
34-428 |
3.12e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 3.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 34 KVEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfl 113
Cdd:PTZ00121 1565 KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE------------- 1631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 114 RNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKqidsqKET 193
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-----AEE 1706
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 194 LLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKievQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQ 273
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK---KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 274 -LKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMlhnLREKLKNAQLDADKSNVMA 352
Cdd:PTZ00121 1784 eLDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM---QLEEADAFEKHKFNKNNEN 1860
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975378 353 LQQGIQERDSQIKmlTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAE 428
Cdd:PTZ00121 1861 GEDGNKEADFNKE--KDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETRE 1934
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
17-277 |
2.14e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.60 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 17 DLPRQEELADNLLISLSKvEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLEN 96
Cdd:TIGR02169 234 ALERQKEAIERQLASLEE-ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 97 ELEMAQQSAGGR-----DTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKK 171
Cdd:TIGR02169 313 KERELEDAEERLakleaEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 172 KNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEME 251
Cdd:TIGR02169 393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELY 472
|
250 260
....*....|....*....|....*.
gi 767975378 252 KMTDEYNRMKAIVHQTDNVIDQLKKE 277
Cdd:TIGR02169 473 DLKEEYDRVEKELSKLQRELAEAEAQ 498
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
87-563 |
4.51e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.88 E-value: 4.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 87 LKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDREL----EDMEKELEKEKKVNEQLALRNEEAENENSKL 162
Cdd:pfam15921 236 LKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEItgltEKASSARSQANSIQSQLEIIQEQARNQNSMY 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 163 RRENKRLKKKNEQLCQDIIDYQKQIDSQKETLlsrrgedsdyRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKN 242
Cdd:pfam15921 316 MRQLSDLESTVSQLRSELREAKRMYEDKIEEL----------EKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 243 LEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMvavnakveewklilsskdd 322
Cdd:pfam15921 386 LHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM------------------- 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 323 eiiEYQqmlhnlreklknaqldadksnvMALQQGIQERDSQIKMLTEQVEQyTKEMEKNtcIIEDLknelqrnkgasTLS 402
Cdd:pfam15921 447 ---ERQ----------------------MAAIQGKNESLEKVSSLTAQLES-TKEMLRK--VVEEL-----------TAK 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 403 QQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEIL 482
Cdd:pfam15921 488 KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEIL 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 483 TKEI-NKLELKISDFLDENEALRERVGLEPKT---MIDLTEFRNSKHLKQQQYRAenqiLLKEIESLEEERLDLK----- 553
Cdd:pfam15921 568 RQQIeNMTQLVGQHGRTAGAMQVEKAQLEKEIndrRLELQEFKILKDKKDAKIRE----LEARVSDLELEKVKLVnagse 643
|
490
....*....|..
gi 767975378 554 --KKIRQMAQER 563
Cdd:pfam15921 644 rlRAVKDIKQER 655
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
2125-2266 |
2.41e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.31 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2125 REKEEIDQENDELKRQIKRLtsglqgkpltdnkQSLIEELQRKVKKLENQLEGKVEEVD-----LKPMKeKNAKEELIRW 2199
Cdd:COG2433 399 REKEHEERELTEEEEEIRRL-------------EEQVERLEAEVEELEAELEEKDERIErlereLSEAR-SEERREIRKD 464
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767975378 2200 EEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKL----KTTGMTVDQVLGIRA 2266
Cdd:COG2433 465 REISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGELVPVKVVekftKEAIRRLEEEYGLKE 535
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
331-1155 |
2.63e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.12 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 331 LHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLK---NELQRNKGASTLSQQTHM 407
Cdd:TIGR02168 215 YKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlevSELEEEIEELQKELYALA 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 408 KIQSTLD----ILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYEsgvYGLEDAVVEIKNCKNQIKIRDREIEILT 483
Cdd:TIGR02168 295 NEISRLEqqkqILRERLANLERQLEELEAQLEELESKLDELAEELAELE---EKLEELKEELESLEAELEELEAELEELE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 484 KEINKLELKISDFLDENEALRERVGLEPKTMIdltefRNSKHLKQQQYRAENqiLLKEIESLEEERLDLKKKIRQMAQER 563
Cdd:TIGR02168 372 SRLEELEEQLETLRSKVAQLELQIASLNNEIE-----RLEARLERLEDRRER--LQQEIEELLKKLEEAELKELQAELEE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 564 GKRSATSGLTTEDLNLTENISQGDRISERKLDLLSLKN-MSEAQSKIRSSDKAELLHRRSSFNTPQSDQNETEENMTIGS 642
Cdd:TIGR02168 445 LEEELEELQEELERLEEALEELREELEEAEQALDAAEReLAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 643 LSRMLSeihhsVESGMHPFVpLTRLSSSMQ--VKENSTP---------ETITIREIFKAPCLQSSRNLESlVSTFSRESH 711
Cdd:TIGR02168 525 LSELIS-----VDEGYEAAI-EAALGGRLQavVVENLNAakkaiaflkQNELGRVTFLPLDSIKGTEIQG-NDREILKNI 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 712 EEINDICLFSDDCMKKVSRSHQALEKTSFVQKSnssfhgLSTASDIMQKLslRQKSAIFCQQIHENRADmdksQVATLEE 791
Cdd:TIGR02168 598 EGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD------LDNALELAKKL--RPGYRIVTLDGDLVRPG----GVITGGS 665
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 792 EQVHSQVKYADINLKEdiiksevpLQTEILKNKLKVNLpdpVSITAQSKLSQINSLENLIEQLRRELVFLRSQNEIIAQE 871
Cdd:TIGR02168 666 AKTNSSILERRREIEE--------LEEKIEELEEKIAE---LEKALAELRKELEELEEELEQLRKELEELSRQISALRKD 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 872 FLIKEAECRNAdielehhrsqAEQNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKD 951
Cdd:TIGR02168 735 LARLEAEVEQL----------EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 952 PDVKGGETSLIIPSLERLVNAIESknaegifdaslhLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLE 1031
Cdd:TIGR02168 805 LDELRAELTLLNEEAANLRERLES------------LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1032 KE-TSLLRQSEGSNVvfkgidlpdgiapsSASIINSQNEYLIHLLQELENK----EKKLKNLEDSLEDYNRKFAVIRhQQ 1106
Cdd:TIGR02168 873 SElEALLNERASLEE--------------ALALLRSELEELSEELRELESKrselRRELEELREKLAQLELRLEGLE-VR 937
|
810 820 830 840
....*....|....*....|....*....|....*....|....*....
gi 767975378 1107 SLLYKEYLSEKetWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNAL 1155
Cdd:TIGR02168 938 IDNLQERLSEE--YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
115-567 |
3.26e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.74 E-value: 3.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 115 NEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLK---------KKNEQLCQDIIDYQK 185
Cdd:PRK03918 207 REINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIReleerieelKKEIEELEEKVKELK 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 186 QIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMR------KNLEESVQEMEKMTDEYNR 259
Cdd:PRK03918 287 ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEelkkklKELEKRLEELEERHELYEE 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 260 MKAIVHQTDNV---------------IDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAK--------------- 309
Cdd:PRK03918 367 AKAKKEELERLkkrltgltpeklekeLEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELkkakgkcpvcgrelt 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 310 -------VEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQErdsQIKMLTEQVEQYTKE-MEKN 381
Cdd:PRK03918 447 eehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAE---QLKELEEKLKKYNLEeLEKK 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 382 TCIIEDLKNELQRNKGastlsqqthmKIQSTLDILKEKtKEAERTAELAEADAREKDKELVEALKRL--------KDYES 453
Cdd:PRK03918 524 AEEYEKLKEKLIKLKG----------EIKSLKKELEKL-EELKKKLAELEKKLDELEEELAELLKELeelgfesvEELEE 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 454 GVYGLEDA---VVEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGlEPKTMIDLTEFRNSKHlKQQQ 530
Cdd:PRK03918 593 RLKELEPFyneYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE-ELEKKYSEEEYEELRE-EYLE 670
|
490 500 510
....*....|....*....|....*....|....*..
gi 767975378 531 YRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRS 567
Cdd:PRK03918 671 LSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
|
|
| SHE3 |
pfam17078 |
SWI5-dependent HO expression protein 3; SWI5-dependent HO expression protein 3 (She3) is an ... |
162-297 |
6.94e-03 |
|
SWI5-dependent HO expression protein 3; SWI5-dependent HO expression protein 3 (She3) is an RNA-binding protein that binds specific mRNAs, including the mRNA of Ash1, which is invalid in cell-fate determination. She3 acts as an adapter protein that docks the myosin motor Myo4p onto an Ash1-She2p ribonucleoprotein complex. She3 seems to bind to Myo4p and Shep2p via different domains.
Pssm-ID: 293683 [Multi-domain] Cd Length: 228 Bit Score: 40.49 E-value: 6.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 162 LRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRK 241
Cdd:pfam17078 15 LTKTNLQLTVQSQNLLSKLEIAQQKESKFLENLASLKHENDNLSSMLNRKERRLKDLEDQLSELKNSYEELTESNKQLKK 94
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 767975378 242 NLEESVQEMEKMTDEYNRMKAivhQTDNVIDQLKKENDHYQLQVQELT---DLLKSKNE 297
Cdd:pfam17078 95 RLENSSASETTLEAELERLQI---QYDALVDSQNEYKDHYQQEINTLQeslEDLKLENE 150
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CEP209_CC5 |
pfam16574 |
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ... |
1576-1703 |
1.97e-45 |
|
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.
Pssm-ID: 465184 [Multi-domain] Cd Length: 128 Bit Score: 160.63 E-value: 1.97e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1576 TMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNRELVKD 1655
Cdd:pfam16574 1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 767975378 1656 KEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLER 1703
Cdd:pfam16574 81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1369-2176 |
6.66e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 81.26 E-value: 6.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1369 HLRTSLKQMEERNFELETKFAELTKinldaqkvEQMLRDELADSVSKAVSDADRqriLELEKNEMELKVEV------SKL 1442
Cdd:TIGR02168 226 ELALLVLRLEELREELEELQEELKE--------AEEELEELTAELQELEEKLEE---LRLEVSELEEEIEElqkelyALA 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1443 REISDIaRRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKlhqhnvSLQLSEATALGKLESITSKLQKMEAYN 1522
Cdd:TIGR02168 295 NEISRL-EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA------ELEEKLEELKEELESLEAELEELEAEL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1523 LRLEQKLDEKEQALYYARlegrNRAKHLRQTIQSLRRQFsgalplaQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNME 1602
Cdd:TIGR02168 368 EELESRLEELEEQLETLR----SKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1603 NKTLEMELKLKGLEELISTLKDTkgAQKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQ 1682
Cdd:TIGR02168 437 ELQAELEELEEELEELQEELERL--EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1683 QNKFHEERQMAWDQREVDLERQLDIF----DRQQNEILNAAQKFEEATGSIPDPSLPLPNQLE---IALRKIKENIRIIL 1755
Cdd:TIGR02168 515 QSGLSGILGVLSELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPldsIKGTEIQGNDREIL 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1756 ETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELR--LRLPATAEREKLIAELGRKEMEPKSHHTLKIAhQTIANMQ 1833
Cdd:TIGR02168 595 KNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDnaLELAKKLRPGYRIVTLDGDLVRPGGVITGGSA-KTNSSIL 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1834 ARLNQKEEVLKKYQRLLEKAREEQREIVkkheedlhilhhRLELQADSSLNKFKQTAWDLMKQSPTPVPTNKHFIRLAEM 1913
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALA------------ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1914 EQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEfeniklqlqenHEDEVKKVKAEVEDLKYLLDQSQKESQCLKS 1993
Cdd:TIGR02168 742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE-----------AEAEIEELEAQIEQLKEELKALREALDELRA 810
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1994 ELQAQKEANSRAptttmRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDrhtre 2073
Cdd:TIGR02168 811 ELTLLNEEAANL-----RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN----- 880
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2074 lktQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG--K 2151
Cdd:TIGR02168 881 ---ERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEeaE 957
|
810 820
....*....|....*....|....*
gi 767975378 2152 PLTDNKQSLIEELQRKVKKLENQLE 2176
Cdd:TIGR02168 958 ALENKIEDDEEEARRRLKRLENKIK 982
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
843-1562 |
1.41e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 1.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 843 QINSLENLIEQLRRELVFLRSQNEIIAQEFLIKEAECRNADIELEHHRSQAEQnefLSRELIEKERDLERSRTVIAKFQN 922
Cdd:TIGR02168 226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE---LEEEIEELQKELYALANEISRLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 923 KLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIfdaslHLKAQVDQLTGRNEEL 1002
Cdd:TIGR02168 303 QKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE-----ELEAELEELESRLEEL 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1003 RQELRESRKEAINYSQQLAKANLKIDHLEKEtslLRQSEGSNVVFKGIDLPDGIAPSSASIINSQneylihllQELENKE 1082
Cdd:TIGR02168 378 EEQLETLRSKVAQLELQIASLNNEIERLEAR---LERLEDRRERLQQEIEELLKKLEEAELKELQ--------AELEELE 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1083 KKLKNLEDSLEDYNRkfavirhqqsllykeylsEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEM 1162
Cdd:TIGR02168 447 EELEELQEELERLEE------------------ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1163 KKILAENSRK-------ITVLQVNEK---------SLIRQYTTLVELERQLR-----KENEKQK-----------NELLS 1210
Cdd:TIGR02168 509 KALLKNQSGLsgilgvlSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKaiaflKQNELGRvtflpldsikgTEIQG 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1211 MEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLS----ELELANKQYNELTAKYRDI-----------------LQK 1269
Cdd:TIGR02168 589 NDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvdDLDNALELAKKLRPGYRIVtldgdlvrpggvitggsAKT 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1270 DNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKLGNEssmdkakksitnsdivsISKKITML 1349
Cdd:TIGR02168 669 NSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-----------------LSRQISAL 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1350 EMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKiNLDAQKVEQMLRDELADSVSKAVSdADRQRILELE 1429
Cdd:TIGR02168 732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAEAEIEELEAQIEQLKEELK-ALREALDELR 809
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1430 KNEMELKVEVSKLRE-----ISDIARRQVEILNAQQQSRDK--EVESLRMQLLDYQAQSDEKSLIAKLHQHNV-SLQLSE 1501
Cdd:TIGR02168 810 AELTLLNEEAANLRErleslERRIAATERRLEDLEEQIEELseDIESLAAEIEELEELIEELESELEALLNERaSLEEAL 889
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767975378 1502 ATALGKLESITSKLQKMEAYNLRLEQKLDEKEQAL--YYARLEGrnrakhLRQTIQSLRRQFS 1562
Cdd:TIGR02168 890 ALLRSELEELSEELRELESKRSELRRELEELREKLaqLELRLEG------LEVRIDNLQERLS 946
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1250-2175 |
1.39e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.47 E-value: 1.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1250 ELANKQYNELTAKYRDI--LQKDNM---LVQRTSNLEHLECENISLKE---QVESINKELEITKEKLHTIEQAWEQET-K 1320
Cdd:PTZ00121 1031 ELTEYGNNDDVLKEKDIidEDIDGNhegKAEAKAHVGQDEGLKPSYKDfdfDAKEDNRADEATEEAFGKAEEAKKTETgK 1110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1321 LGNESSMDKAKKSItnSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTS-LKQMEERNFELETKFAELTKINLDAQ 1399
Cdd:PTZ00121 1111 AEEARKAEEAKKKA--EDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEdARKAEEARKAEDAKKAEAARKAEEVR 1188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1400 KVEQMLRDELADSVSKAVSDADRQRILELEKNEMELKVEvsKLREISDIARRQVEilnAQQQSRDKEVESLRMQLLDYQA 1479
Cdd:PTZ00121 1189 KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAE--AVKKAEEAKKDAEE---AKKAEEERNNEEIRKFEEARMA 1263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1480 QSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRR 1559
Cdd:PTZ00121 1264 HFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKK 1343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1560 --QFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGA---QKVINW 1634
Cdd:PTZ00121 1344 aaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAaakKKADEA 1423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1635 HMKIEELR-LQELKLNRELVKDKEEIKYLnniiSEYERTISSLEEEIVQQNKFHEERQMAWDQREVD-LERQLDIFDRQQ 1712
Cdd:PTZ00121 1424 KKKAEEKKkADEAKKKAEEAKKADEAKKK----AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADeAKKKAEEAKKKA 1499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1713 NEilnaAQKFEEATGSIPDPSLPLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINEL 1792
Cdd:PTZ00121 1500 DE----AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED 1575
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1793 RLRLPATAE-----REKLIAELGRKEMEPKSHHTLKIAHQTIANMQA-RLNQKEEVLKKYQRLLEKAREEQR--EIVKKH 1864
Cdd:PTZ00121 1576 KNMALRKAEeakkaEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAeELKKAEEEKKKVEQLKKKEAEEKKkaEELKKA 1655
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1865 EEDLHILHHRLELQADSSLNKFKQtawdlmkqsptpvptnkhfIRLAEMEQTVAEQddslssllvklkKVSQDLERQREI 1944
Cdd:PTZ00121 1656 EEENKIKAAEEAKKAEEDKKKAEE-------------------AKKAEEDEKKAAE------------ALKKEAEEAKKA 1704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1945 TELKVKEFENIKLQLQENHEDEVKKVKaeVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALK 2024
Cdd:PTZ00121 1705 EELKKKEAEEKKKAEELKKAEEENKIK--AEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2025 E--KQQKALSRALLELRAEMTAAAEERIISATSQKEAHLN-VQQIVDRHTRELkTQVEDLNENLLKLKEALKTSKNRENS 2101
Cdd:PTZ00121 1783 EelDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINdSKEMEDSAIKEV-ADSKNMQLEEADAFEKHKFNKNNENG 1861
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767975378 2102 LTDNLN-DLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQL 2175
Cdd:PTZ00121 1862 EDGNKEaDFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEI 1936
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1749-2138 |
3.51e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.85 E-value: 3.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1749 ENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPaTAEREKLIAELGRKEMEPKSHHTLKIAHQT 1828
Cdd:TIGR02168 155 EERRAIFEEAAGISKYKERRKETERKLERTRENLDRLEDILNELERQLK-SLERQAEKAERYKELKAELRELELALLVLR 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1829 IANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEdlhilhHRLELQADSSLNKFKQTAWDLMKQsptpvptnkhfi 1908
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEE------LRLEVSELEEEIEELQKELYALAN------------ 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1909 RLAEMEQTVAEQDDSLSSLLVKLKKVS---QDLERQREITELKVKEFENIKLQLQENHE---DEVKKVKAEVEDLKYLLD 1982
Cdd:TIGR02168 296 EISRLEQQKQILRERLANLERQLEELEaqlEELESKLDELAEELAELEEKLEELKEELEsleAELEELEAELEELESRLE 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1983 QSQKESQCLKSEL-QAQKEANSraptttMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHL 2061
Cdd:TIGR02168 376 ELEEQLETLRSKVaQLELQIAS------LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767975378 2062 NvqqivdrhtrELKTQVEDLNENLLKLKEALKTSKNRensltdnLNDLNNELQKKQKAYNKILREKEEIDQENDELK 2138
Cdd:TIGR02168 450 E----------ELQEELERLEEALEELREELEEAEQA-------LDAAERELAQLQARLDSLERLQENLEGFSEGVK 509
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1927-2220 |
8.10e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.11 E-value: 8.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1927 LLVKLKKVSQDLERQREITELKVKEFENIKLQLQEnHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQaqKEANSRAP 2006
Cdd:COG1196 230 LLLKLRELEAELEELEAELEELEAELEELEAELAE-LEAELEELRLELEELELELEEAQAEEYELLAELA--RLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2007 TTTMRN----LVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRhTRELKTQVEDLN 2082
Cdd:COG1196 307 LEERRReleeRLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE-LAEAEEELEELA 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2083 ENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQgkpltdNKQSLIE 2162
Cdd:COG1196 386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA------ELEEEEE 459
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 767975378 2163 ELQRKVKKLENQLEGKVEEV-DLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKE 2220
Cdd:COG1196 460 ALLELLAELLEEAALLEAALaELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1634-2218 |
1.22e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.72 E-value: 1.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1634 WHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQN 1713
Cdd:COG1196 230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1714 EILNAAQKFEEATgsipdpslplpNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELR 1793
Cdd:COG1196 310 RRRELEERLEELE-----------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1794 LRLpATAEREKLIAELGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEDLHILHH 1873
Cdd:COG1196 379 EEL-EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1874 RLELQADSSLNKFKQTAWDlmkqsptpvptnkhfirlAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFE 1953
Cdd:COG1196 458 EEALLELLAELLEEAALLE------------------AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1954 N-IKLQLQENHEDEVKKVKAEVEDL-----KYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQ 2027
Cdd:COG1196 520 RgLAGAVAVLIGVEAAYEAALEAALaaalqNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2028 QKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLN 2107
Cdd:COG1196 600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2108 DLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLtsglqgkpltdnKQSLIEELQRKVKKLENQLEGKVEEVDLKPM 2187
Cdd:COG1196 680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEER------------LEEELEEEALEEQLEAEREELLEELLEEEEL 747
|
570 580 590
....*....|....*....|....*....|.
gi 767975378 2188 KEKNAKEELIRWEEGKKWQAKIEGIRNKLKE 2218
Cdd:COG1196 748 LEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
866-1673 |
1.42e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 60.54 E-value: 1.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 866 EIIAQEFLIKEAECRNADIELEHH-----RSQAEQNEFLSRELIEKERDlERSRTVIAKFQNKLKELVEENKQLEEGMKE 940
Cdd:PTZ00121 1034 EYGNNDDVLKEKDIIDEDIDGNHEgkaeaKAHVGQDEGLKPSYKDFDFD-AKEDNRADEATEEAFGKAEEAKKTETGKAE 1112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 941 ILQAIKE-MQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQ 1019
Cdd:PTZ00121 1113 EARKAEEaKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEE 1192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1020 LAKAN--LKIDHLEKETSLLRQSEgsnvVFKGIDLPDGIAPSSASIINSQNEYlIHLLQELENKEKKLKNLEDSLEDYNR 1097
Cdd:PTZ00121 1193 LRKAEdaRKAEAARKAEEERKAEE----ARKAEDAKKAEAVKKAEEAKKDAEE-AKKAEEERNNEEIRKFEEARMAHFAR 1267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1098 KFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLED--QVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITV 1175
Cdd:PTZ00121 1268 RQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEakKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEA 1347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1176 LQVNEKSLIRQYTTLVELER--QLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVvdnsvslselELAN 1253
Cdd:PTZ00121 1348 AKAEAEAAADEAEAAEEKAEaaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKA----------AAAK 1417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1254 KQYNELTAKYRDILQKDnmlvqrtsnlehleceniSLKEQVESINKELEItKEKLHTIEQAWEQETKLGNESSMDKAKKS 1333
Cdd:PTZ00121 1418 KKADEAKKKAEEKKKAD------------------EAKKKAEEAKKADEA-KKKAEEAKKAEEAKKKAEEAKKADEAKKK 1478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1334 ITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSlkqmEERNFELETKFAELTKINLDAQKVEQMLRdelADSV 1413
Cdd:PTZ00121 1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA----EEAKKADEAKKAEEAKKADEAKKAEEKKK---ADEL 1551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1414 SKAVsdadrqrilELEKNEMELKVE-VSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQ 1492
Cdd:PTZ00121 1552 KKAE---------ELKKAEEKKKAEeAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1493 HNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEK 1572
Cdd:PTZ00121 1623 EELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1573 FSKTMIQLQNDKLKIMQEMKNSQQEHRNM--ENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNR 1650
Cdd:PTZ00121 1703 KAEELKKKEAEEKKKAEELKKAEEENKIKaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782
|
810 820
....*....|....*....|...
gi 767975378 1651 ELVKDKEEIKYLnniisEYERTI 1673
Cdd:PTZ00121 1783 EELDEEDEKRRM-----EVDKKI 1800
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1526-2231 |
1.45e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.46 E-value: 1.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1526 EQKLDEKEQALyyARLEGRnrAKHLRQTIQSLRRQFSGAlplaqqEKFSKTMIQLQNDKLKIM-QEMKNSQQEHRNMENK 1604
Cdd:TIGR02168 178 ERKLERTRENL--DRLEDI--LNELERQLKSLERQAEKA------ERYKELKAELRELELALLvLRLEELREELEELQEE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1605 TLEMELKLKGLEELISTLkdtkgaqkvinwHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQN 1684
Cdd:TIGR02168 248 LKEAEEELEELTAELQEL------------EEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1685 KFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLPN----------QLEIALRKIKENIRII 1754
Cdd:TIGR02168 316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEElesrleeleeQLETLRSKVAQLELQI 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1755 LETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPAT------AEREKLIAELGRKEMEPKS-HHTLKIAHQ 1827
Cdd:TIGR02168 396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAeleeleEELEELQEELERLEEALEElREELEEAEQ 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1828 TIANMQARLNQKEEVLKKYQRLLEKAREEQREI--VKKHEEDLHILHHRL--------------------ELQA--DSSL 1883
Cdd:TIGR02168 476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVkaLLKNQSGLSGILGVLselisvdegyeaaieaalggRLQAvvVENL 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1884 NKFKQtAWDLMKQSPT------PVPTNKHFIRLAEMEQTVAEQDDSLSSLL------VKLKKVSQDL------------- 1938
Cdd:TIGR02168 556 NAAKK-AIAFLKQNELgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdPKLRKALSYLlggvlvvddldna 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1939 -ERQREITE----------------LKVKEFENIKLQLQENhEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQA--QK 1999
Cdd:TIGR02168 635 lELAKKLRPgyrivtldgdlvrpggVITGGSAKTNSSILER-RREIEELEEKIEELEEKIAELEKALAELRKELEEleEE 713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2000 EANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQqivdrhtrELKTQVE 2079
Cdd:TIGR02168 714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA--------EAEAEIE 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2080 DLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG-KPLTDNKQ 2158
Cdd:TIGR02168 786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESlAAEIEELE 865
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2159 SLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKK--------WQAKIEGIRNKLKEKEGEVFTLTKQL 2230
Cdd:TIGR02168 866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSelrreleeLREKLAQLELRLEGLEVRIDNLQERL 945
|
.
gi 767975378 2231 N 2231
Cdd:TIGR02168 946 S 946
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1571-2176 |
4.62e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.54 E-value: 4.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1571 EKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGaqkvinwhmKIEELRLQELKLNR 1650
Cdd:PRK03918 182 EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE---------EIEELEKELESLEG 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1651 ELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQmawdqREVDLERQLDIFDRQQNEILNAAQKFEEatgsip 1730
Cdd:PRK03918 253 SKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAE-----EYIKLSEFYEEYLDELREIEKRLSRLEE------ 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1731 dpslpLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQnILSRDKVINELRLRLpATAEREKLIAELG 1810
Cdd:PRK03918 322 -----EINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEE-AKAKKEELERLKKRL-TGLTPEKLEKELE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1811 RKEmepKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREE----QREIVKKHEEDLhilhhrlelqadsslnkf 1886
Cdd:PRK03918 395 ELE---KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcGRELTEEHRKEL------------------ 453
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1887 kqtawdlmkqsptpvpTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELK--VKEFENIKLQLQENHE 1964
Cdd:PRK03918 454 ----------------LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKelAEQLKELEEKLKKYNL 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1965 DEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRaptttmrnlVERLKSQLALKEKQQKALSRALLELRAEMTA 2044
Cdd:PRK03918 518 EELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKK---------LAELEKKLDELEEELAELLKELEELGFESVE 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2045 AAEERIISATSQKEAHLNVQQIVDRHTRELK------TQVEDLNENLLKLKEALKTSKNRENSLTDNLND-----LNNEL 2113
Cdd:PRK03918 589 ELEERLKELEPFYNEYLELKDAEKELEREEKelkkleEELDKAFEELAETEKRLEELRKELEELEKKYSEeeyeeLREEY 668
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2114 QKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG-----KPLTDNKQSL--IEELQRKVKKLENQLE 2176
Cdd:PRK03918 669 LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEErekakKELEKLEKALerVEELREKVKKYKALLK 738
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1506-2279 |
6.66e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.14 E-value: 6.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1506 GKLESITSKLQKMEAYnLRLEQKLDEKEQALYYARLEGRNraKHLRQTIQSLRRQfsgalplaqQEKFSKTMIQLQNDKL 1585
Cdd:TIGR02168 200 RQLKSLERQAEKAERY-KELKAELRELELALLVLRLEELR--EELEELQEELKEA---------EEELEELTAELQELEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1586 KIMQEMKnsqqEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKV--INWHMKIEELRLQELKLNRELVKDKEEIKYLN 1663
Cdd:TIGR02168 268 KLEELRL----EVSELEEEIEELQKELYALANEISRLEQQKQILRErlANLERQLEELEAQLEELESKLDELAEELAELE 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1664 NIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFD-------RQQNEILNAAQKFEEATGSIPD----- 1731
Cdd:TIGR02168 344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAqlelqiaSLNNEIERLEARLERLEDRRERlqqei 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1732 ---PSLPLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPAtaerekLIAE 1808
Cdd:TIGR02168 424 eelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS------LERL 497
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1809 LGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQRE-IVKKHEEDLhilhhRLELQADSSLNKFK 1887
Cdd:TIGR02168 498 QENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQaVVVENLNAA-----KKAIAFLKQNELGR 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1888 QTAWDLMKQSPTPVPTNKHFIR---------LAEMEQTVAEQDDSLSSLLVKL--------------------------- 1931
Cdd:TIGR02168 573 VTFLPLDSIKGTEIQGNDREILkniegflgvAKDLVKFDPKLRKALSYLLGGVlvvddldnalelakklrpgyrivtldg 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1932 --------------KKVSQDLERQREITELKvkefENIKLQLQENHE--DEVKKVKAEVEDLKYLLDQSQKESQCLKSEL 1995
Cdd:TIGR02168 653 dlvrpggvitggsaKTNSSILERRREIEELE----EKIEELEEKIAEleKALAELRKELEELEEELEQLRKELEELSRQI 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1996 QAQKEansraptttmrnLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAhlnvqqivdrhtrelK 2075
Cdd:TIGR02168 729 SALRK------------DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA---------------E 781
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2076 TQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG-KPLT 2154
Cdd:TIGR02168 782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESlAAEI 861
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2155 DNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKK--------WQAKIEGIRNKLKEKEGEVFTL 2226
Cdd:TIGR02168 862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSelrreleeLREKLAQLELRLEGLEVRIDNL 941
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767975378 2227 TKQLN--------TLKDLFAKADKEKLTLQRKLKTTGMTVDQvLGIRALESEKELEELKKR 2279
Cdd:TIGR02168 942 QERLSeeysltleEAEALENKIEDDEEEARRRLKRLENKIKE-LGPVNLAAIEEYEELKER 1001
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1523-2144 |
9.16e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 57.64 E-value: 9.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1523 LRLEQKLDEKEQALYYARLEG-RNRAKHLRQTIQSLRRQFSGALplAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNM 1601
Cdd:COG1196 216 RELKEELKELEAELLLLKLRElEAELEELEAELEELEAELEELE--AELAELEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1602 ENKTLEMELKLKGLEELISTLKDTKGAQKVinwhmKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIV 1681
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEE-----ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1682 QQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATgsipdpslplpNQLEIALRKIKENIRIILETRATC 1761
Cdd:COG1196 369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL-----------ERLERLEEELEELEEALAELEEEE 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1762 KSLEEKLKEKESALRLAEQNILSRDKVINELRLRLpatAEREKLIAELGRKEMEPKSHHTLKIAHQtiANMQARLNQ-KE 1840
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEA---ALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGvKA 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1841 EVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSPTPVPTnkhFIRLAEMEQTVAEQ 1920
Cdd:COG1196 513 ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT---FLPLDKIRARAALA 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1921 DDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQcLKSELQAQKE 2000
Cdd:COG1196 590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA-GGSLTGGSRR 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2001 ANSRAptttmRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVED 2080
Cdd:COG1196 669 ELLAA-----LLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767975378 2081 LNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQK-------AYNKILREKEEIDQENDELKRQIKRL 2144
Cdd:COG1196 744 EEELLEEEALEELPEPPDLEELERELERLEREIEALGPvnllaieEYEELEERYDFLSEQREDLEEARETL 814
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
243-563 |
1.91e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.00 E-value: 1.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 243 LEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDpimvAVNAKVEEWKLILSSKDD 322
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEE----KLKERLEELEEDLSSLEQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 323 EIIEYQQMLHNLREKLknAQLDADKSNVMALQQGIQ--ERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGAST 400
Cdd:TIGR02169 752 EIENVKSELKELEARI--EELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 401 LSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDRE-- 478
Cdd:TIGR02169 830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEle 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 479 --IEILTKEINKLELKISDFLDENEALRERVGL---EPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEE---RL 550
Cdd:TIGR02169 910 aqIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVlkrLD 989
|
330
....*....|...
gi 767975378 551 DLKKKIRQMAQER 563
Cdd:TIGR02169 990 ELKEKRAKLEEER 1002
|
|
| DUF1633 |
pfam07794 |
Protein of unknown function (DUF1633); This family contains sequences derived from a group of ... |
2052-2228 |
2.25e-07 |
|
Protein of unknown function (DUF1633); This family contains sequences derived from a group of hypothetical proteins expressed by Arabidopsis thaliana. These sequences are highly similar and the region concerned is about 100 residues long.
Pssm-ID: 116408 [Multi-domain] Cd Length: 698 Bit Score: 56.43 E-value: 2.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2052 SATSQKEAHLNVQQivdrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQ----KKQKAYNKILRek 2127
Cdd:pfam07794 458 RAIREEDPHLGADQ-----DREVRFGAEGIVPGIERLKIELSTSKDLEKGYAEKIGFMEMEFGgleaDKQMARNQIHR-- 530
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2128 eeIDQENDELKRQIKRLTSGLQG--KPLTDNK-------QSLIEELQRK--VKKLENQLEGKVEEVDLK-PMKEKNAKEE 2195
Cdd:pfam07794 531 --LEEKKDELSKKVLDLTSIAQGakKAVHDAKvelaaayLKLLAGIKDKwvAKKEFTVLEGQAAEVESNlALIDQITKAA 608
|
170 180 190
....*....|....*....|....*....|...
gi 767975378 2196 LIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTK 2228
Cdd:pfam07794 609 IDLTLEKPRFQAEIDDLEARCKLKEVSDFTLSK 641
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1250-1559 |
9.28e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.56 E-value: 9.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1250 ELANKQYNELTAKYRDILQKdnmLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQEtklgnessmdK 1329
Cdd:COG1196 221 ELKELEAELLLLKLRELEAE---LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA----------Q 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1330 AKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDEL 1409
Cdd:COG1196 288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1410 ADSVSKAVS-----DADRQRILELEKNEMELKVEVSKL-REISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDE 1483
Cdd:COG1196 368 LEAEAELAEaeeelEELAEELLEALRAAAELAAQLEELeEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975378 1484 KSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALyyARLEGRNRAKHLRQTIQSLRR 1559
Cdd:COG1196 448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGVKAALLLAGLRG 521
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
27-633 |
1.05e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.29 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 27 NLLISLSKVEVNELKSEKQEN------VIHLFRITQSLMKMK----AQEVELALEEVEKAGEEQAKFeNQLKTKVMKLEN 96
Cdd:TIGR02168 224 ELELALLVLRLEELREELEELqeelkeAEEELEELTAELQELeeklEELRLEVSELEEEIEELQKEL-YALANEISRLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 97 ELEMAQQSAggrdtRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQL 176
Cdd:TIGR02168 303 QKQILRERL-----ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 177 CQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEanEKIEVQNQEMRKNLEESVQEMEKMTDE 256
Cdd:TIGR02168 378 EEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQEE 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 257 YNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKS-----KNEEDDPIMVAVNAKVEEWKLILSSKDDEIIE----Y 327
Cdd:TIGR02168 456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSlerlqENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegY 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 328 QQMLHN-LREKLKN----------------AQLDADKSNVMALQ----QGIQERDSQIKMLTEQVEQYTKEMEK------ 380
Cdd:TIGR02168 536 EAAIEAaLGGRLQAvvvenlnaakkaiaflKQNELGRVTFLPLDsikgTEIQGNDREILKNIEGFLGVAKDLVKfdpklr 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 381 --------NTCIIEDLKN--ELQRNKGASTL------------------SQQTHMKIQSTldilKEKTKEAERTAELAEA 432
Cdd:TIGR02168 616 kalsyllgGVLVVDDLDNalELAKKLRPGYRivtldgdlvrpggvitggSAKTNSSILER----RREIEELEEKIEELEE 691
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 433 DAREKDKELVEALKRLKDYEsgvygledavveiknckNQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGLEPK 512
Cdd:TIGR02168 692 KIAELEKALAELRKELEELE-----------------EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 513 TMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQmaQERGKRSATSGLTTEDLNLTENISQGDRISER 592
Cdd:TIGR02168 755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA--LREALDELRAELTLLNEEAANLRERLESLERR 832
|
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 767975378 593 KLDLLSLKNMSEAQSKIRSSDKAELLHRRSSFNTPQSDQNE 633
Cdd:TIGR02168 833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES 873
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
93-404 |
1.59e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.91 E-value: 1.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 93 KLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKK 172
Cdd:TIGR02168 217 ELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 173 NEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEK 252
Cdd:TIGR02168 297 ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 253 MTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTD-LLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQML 331
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDrRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEEL 456
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767975378 332 HNLREKLKNA--QLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKntcIIEDLKNELQRNKGASTLSQQ 404
Cdd:TIGR02168 457 ERLEEALEELreELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG---VKALLKNQSGLSGILGVLSEL 528
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
837-1214 |
1.59e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.79 E-value: 1.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 837 AQSKLSQ----INSLENLIEQLRRELVFLRSQNEIiAQEFLIKEAECRNADIELehhrsqaeqnefLSRELIEKERDLER 912
Cdd:COG1196 177 AERKLEAteenLERLEDILGELERQLEPLERQAEK-AERYRELKEELKELEAEL------------LLLKLRELEAELEE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 913 SRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIEsknaegifdaslHLKAQV 992
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------------RLEERR 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 993 DQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSegsnvvfkgidlpdgiapssasiinsqneyLI 1072
Cdd:COG1196 312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE------------------------------LA 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1073 HLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKEtwktESKTIKEEKRKLEDQVQQDAIKVKEYNNLL 1152
Cdd:COG1196 362 EAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE----AEEALLERLERLEEELEELEEALAELEEEE 437
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767975378 1153 NALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAE 1214
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1871-2143 |
2.47e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.00 E-value: 2.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1871 LHHRLELQADSSLNKFKQTawdlmkQSPTPVPTNKHFIRlAEM--EQTVAEQDDSLSSLLVKLKKVSQDLERQREitelK 1948
Cdd:COG4913 182 LRRRLGIGSEKALRLLHKT------QSFKPIGDLDDFVR-EYMleEPDTFEAADALVEHFDDLERAHEALEDARE----Q 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1949 VKEFEniklQLQENHEdEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAptttmrnLVERLKSQLALKEKQQ 2028
Cdd:COG4913 251 IELLE----PIRELAE-RYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRA-------ELARLEAELERLEARL 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2029 KALSRALLELRAEMT-------AAAEERIISATSQKEAHLNVQQIVDRHTRELKTQV----EDLNENLLKLKEALKTSKN 2097
Cdd:COG4913 319 DALREELDELEAQIRgnggdrlEQLEREIERLERELEERERRRARLEALLAALGLPLpasaEEFAALRAEAAALLEALEE 398
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 767975378 2098 RENSLTDNLNDLNNELQKKQKAYNKILREKEE-------IDQENDELKRQIKR 2143
Cdd:COG4913 399 ELEALEEALAEAEAALRDLRRELRELEAEIASlerrksnIPARLLALRDALAE 451
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1740-2245 |
3.18e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 52.76 E-value: 3.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1740 LEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATA-EREKLIAELGRKEMEPKS 1818
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELReELEKLEKEVKELEELKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1819 HHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEdlhilhhrLELQAD--SSLNKFKqtawdlmkq 1896
Cdd:PRK03918 240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE--------LKEKAEeyIKLSEFY--------- 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1897 sptpvptNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITElKVKEFENIKLQLQENHE--DEVKKVKAEV 1974
Cdd:PRK03918 303 -------EEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKK-KLKELEKRLEELEERHElyEEAKAKKEEL 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1975 EDLKYLLDQSQKESqcLKSELQAQKEANsraptTTMRNLVERLKSQLALKEKQQKALSRALLELR-AEMTAAAEERIISA 2053
Cdd:PRK03918 375 ERLKKRLTGLTPEK--LEKELEELEKAK-----EEIEEEISKITARIGELKKEIKELKKAIEELKkAKGKCPVCGRELTE 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2054 TSQKEahlnvqqIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDN--------LNDLNNELQKKQKAYN---- 2121
Cdd:PRK03918 448 EHRKE-------LLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKEseliklkeLAEQLKELEEKLKKYNleel 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2122 -KILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKE----------- 2189
Cdd:PRK03918 521 eKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEEleerlkelepf 600
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767975378 2190 -------KNAKEEL-IRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKL 2245
Cdd:PRK03918 601 yneylelKDAEKELeREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEEL 664
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1841-2150 |
3.55e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 52.63 E-value: 3.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1841 EVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSptpvptnkhfIRLAEMEQTVAEQ 1920
Cdd:COG1196 210 EKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE----------AELEELRLELEEL 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1921 DDSLSSLLVKLKKVSQD---LERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQA 1997
Cdd:COG1196 280 ELELEEAQAEEYELLAElarLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1998 QKEANSRAPTTTmRNLVERLKSQLALKEKQQKALSRALLELRAEmtAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQ 2077
Cdd:COG1196 360 LAEAEEALLEAE-AELAEAEEELEELAEELLEALRAAAELAAQL--EELEEAEEALLERLERLEEELEELEEALAELEEE 436
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767975378 2078 VEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG 2150
Cdd:COG1196 437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
113-448 |
3.92e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 3.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 113 LRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLcqdiidyQKQIDSQKE 192
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-------EERIAQLSK 754
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 193 TLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEEsvqemekMTDEYNRMKAIVHQTDNVID 272
Cdd:TIGR02168 755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE-------LRAELTLLNEEAANLRERLE 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 273 QLKKENDHYQLQVQELTDLLKSKNEEddpiMVAVNAKVEEwkliLSSKDDEIIEYQQMLHNLREKLkNAQLDADKSNVMA 352
Cdd:TIGR02168 828 SLERRIAATERRLEDLEEQIEELSED----IESLAAEIEE----LEELIEELESELEALLNERASL-EEALALLRSELEE 898
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 353 LQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQThmkiqsTLDILKEKtkeaERTAELAEA 432
Cdd:TIGR02168 899 LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL------TLEEAEAL----ENKIEDDEE 968
|
330
....*....|....*.
gi 767975378 433 DAREKDKELVEALKRL 448
Cdd:TIGR02168 969 EARRRLKRLENKIKEL 984
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1434-2234 |
6.76e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 6.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1434 ELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESL---RMQLLDYQAQSDEKSLI-AKLHQHNV-SLQLSEATALGKL 1508
Cdd:TIGR02169 167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLrreREKAERYQALLKEKREYeGYELLKEKeALERQKEAIERQL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1509 ESITSKLQK----MEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSL---RRQFSGALPLAQQEkfsktMIQLQ 1581
Cdd:TIGR02169 247 ASLEEELEKlteeISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELeaeIASLERSIAEKERE-----LEDAE 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1582 NDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVinwhmKIEELRLQELKLNRELVKDKEEIKY 1661
Cdd:TIGR02169 322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-----ELEEVDKEFAETRDELKDYREKLEK 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1662 LNNIISEYERTISSLEEEIVQqnkfheeRQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLpNQLE 1741
Cdd:TIGR02169 397 LKREINELKRELDRLQEELQR-------LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADL-SKYE 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1742 IALRKIKENIRIILETRatcKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAereKLIAELGRKEMEpkshHT 1821
Cdd:TIGR02169 469 QELYDLKEEYDRVEKEL---SKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVH---GTVAQLGSVGER----YA 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1822 LKIAHQTIANMQARLNQKEEVLKKYQRLLeKAREEQREI------VKKHEEDLHILHhrlelqadssLNKFKQTAWDLMK 1895
Cdd:TIGR02169 539 TAIEVAAGNRLNNVVVEDDAVAKEAIELL-KRRKAGRATflplnkMRDERRDLSILS----------EDGVIGFAVDLVE 607
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1896 QSPTPVPTNKHFIRlaemEQTVAEQDDSLSSLLVKLKKVSQD---LERQREITELKVKEFENIKLQLQEnhEDEVKKVKA 1972
Cdd:TIGR02169 608 FDPKYEPAFKYVFG----DTLVVEDIEAARRLMGKYRMVTLEgelFEKSGAMTGGSRAPRGGILFSRSE--PAELQRLRE 681
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1973 EVEDLKYLLDQSQKESQCLKSELQAQKEANSRAP--TTTMRNLVERL-------KSQLALKEKQQKALSRALLELRAEMT 2043
Cdd:TIGR02169 682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASrkIGEIEKEIEQLeqeeeklKERLEELEEDLSSLEQEIENVKSELK 761
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2044 AAAEEriisaTSQKEAHLNVQQ--IVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYN 2121
Cdd:TIGR02169 762 ELEAR-----IEELEEDLHKLEeaLNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ 836
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2122 KILREKEEIDQENDELKRQIKRLTSGLQgkpltdNKQSLIEELQRKVKKLENQLEGKVEEVDlkpmkeknakeelirwee 2201
Cdd:TIGR02169 837 ELQEQRIDLKEQIKSIEKEIENLNGKKE------ELEEELEELEAALRDLESRLGDLKKERD------------------ 892
|
810 820 830
....*....|....*....|....*....|...
gi 767975378 2202 gkKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLK 2234
Cdd:TIGR02169 893 --ELEAQLRELERKIEELEAQIEKKRKRLSELK 923
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1352-2182 |
7.48e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.66 E-value: 7.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1352 KELNERQRAEHCQKMYehLRTSLkqmeernFELETKFAELtkinldaqkveQMLRDELADsVSKAVSDADRQRILELEKN 1431
Cdd:pfam15921 92 RRLNESNELHEKQKFY--LRQSV-------IDLQTKLQEM-----------QMERDAMAD-IRRRESQSQEDLRNQLQNT 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1432 EMELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKsliakLHQHNvSLQLSEATALGKleSI 1511
Cdd:pfam15921 151 VHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKK-----IYEHD-SMSTMHFRSLGS--AI 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1512 TSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPL---AQQEKFSKTMIQLQNdklkIM 1588
Cdd:pfam15921 223 SKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVeitGLTEKASSARSQANS----IQ 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1589 QEMKNSQQEHRNMENKTLEmelKLKGLEELISTLKDTKGAQKVInWHMKIEELRLQELKLNRELVKDKEEIKYLN----N 1664
Cdd:pfam15921 299 SQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRM-YEDKIEELEKQLVLANSELTEARTERDQFSqesgN 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1665 IISEYERTISSLEEEIVQQNKFHEERQMAWDqREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLPNQLEIAL 1744
Cdd:pfam15921 375 LDDQLQKLLADLHKREKELSLEKEQNKRLWD-RDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI 453
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1745 RKIKENIRIILETRATCKSLEEKLKekesalrlaeqnilsrdkvinelrlrlpataereKLIAELGRKEMepkshhTLKI 1824
Cdd:pfam15921 454 QGKNESLEKVSSLTAQLESTKEMLR----------------------------------KVVEELTAKKM------TLES 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1825 AHQTIANMQARLNQKEEVLKKYQRLLEKARE----EQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQsptp 1900
Cdd:pfam15921 494 SERTVSDLTASLQEKERAIEATNAEITKLRSrvdlKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ---- 569
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1901 vptnkhfiRLAEMEQTVAEQDDSLSSLLVKLKKVSQDL-ERQREITELKV------KEFENIKLQLQENHEDEVKKVKAE 1973
Cdd:pfam15921 570 --------QIENMTQLVGQHGRTAGAMQVEKAQLEKEInDRRLELQEFKIlkdkkdAKIRELEARVSDLELEKVKLVNAG 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1974 VEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSqlalkEKQQKALSRALLELRAEMTAAAEER-IIS 2052
Cdd:pfam15921 642 SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKS-----EEMETTTNKLKMQLKSAQSELEQTRnTLK 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2053 ATSQKEAH-LNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEID 2131
Cdd:pfam15921 717 SMEGSDGHaMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLR 796
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|..
gi 767975378 2132 QENDELKRQIKRLTSGLQGKPLTDNK-QSLIEELQRKVKKLENQLEGKVEEV 2182
Cdd:pfam15921 797 SQERRLKEKVANMEVALDKASLQFAEcQDIIQRQEQESVRLKLQHTLDVKEL 848
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1254-1983 |
8.15e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.60 E-value: 8.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1254 KQYNELTAKYRDiLQKDNMLVQRTSNLEHLEceniSLKEQVESINKELEITKEKLHTIEQAWEQetkLGNESSMDKAKKS 1333
Cdd:TIGR02168 213 ERYKELKAELRE-LELALLVLRLEELREELE----ELQEELKEAEEELEELTAELQELEEKLEE---LRLEVSELEEEIE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1334 ITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELADSV 1413
Cdd:TIGR02168 285 ELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1414 SKAV-----SDADRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQ------SD 1482
Cdd:TIGR02168 365 AELEelesrLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaelEE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1483 EKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALyyARLEGRNRAkhLRQTIQSlRRQFS 1562
Cdd:TIGR02168 445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ--ENLEGFSEG--VKALLKN-QSGLS 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1563 GALPLAQQ-----EKFSKTM-------IQL-----QNDKLKIMQEMKN-----------SQQEHRNMENKTLEMELKLKG 1614
Cdd:TIGR02168 520 GILGVLSElisvdEGYEAAIeaalggrLQAvvvenLNAAKKAIAFLKQnelgrvtflplDSIKGTEIQGNDREILKNIEG 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1615 LEELISTL-KDTKGAQKVIN---WHMKI-------EELRLQELKLNRELVKD------------------------KEEI 1659
Cdd:TIGR02168 600 FLGVAKDLvKFDPKLRKALSyllGGVLVvddldnaLELAKKLRPGYRIVTLDgdlvrpggvitggsaktnssilerRREI 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1660 KYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQ---REVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPL 1736
Cdd:TIGR02168 680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQlrkELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1737 PNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAER-EKLIAELGRKEME 1815
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERlESLERRIAATERR 839
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1816 pkshhtLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVK---KHEEDLHILHHRLElQADSSLNKFKQtawd 1892
Cdd:TIGR02168 840 ------LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNeraSLEEALALLRSELE-ELSEELRELES---- 908
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1893 lmkqsptpvptnkhfiRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQRE-ITELKVKEFENIkLQLQENHEDEVKKVK 1971
Cdd:TIGR02168 909 ----------------KRSELRRELEELREKLAQLELRLEGLEVRIDNLQErLSEEYSLTLEEA-EALENKIEDDEEEAR 971
|
810
....*....|..
gi 767975378 1972 AEVEDLKYLLDQ 1983
Cdd:TIGR02168 972 RRLKRLENKIKE 983
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
21-563 |
8.27e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.48 E-value: 8.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 21 QEELADNLLISLSKVEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFEnQLKTKVMKLENELEM 100
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE-EAQAEEYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 101 AQQsaggrDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDI 180
Cdd:COG1196 300 LEQ-----DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 181 IDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRM 260
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 261 KAIVHQTDNVIDQLKKENDHYQLQVQELTDLL---KSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEyqQMLHNLREK 337
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELLEELaeaAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA--GAVAVLIGV 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 338 LKNAQLDADKSNVMALQQGIQERDSQIKMLteqveqytkemekntciIEDLKnelQRNKGASTLSQQTHMKIQSTLDILK 417
Cdd:COG1196 533 EAAYEAALEAALAAALQNIVVEDDEVAAAA-----------------IEYLK---AAKAGRATFLPLDKIRARAALAAAL 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 418 EKTKEAERTAELAEadarekdkELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEILTKEINKLELKISDFL 497
Cdd:COG1196 593 ARGAIGAAVDLVAS--------DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975378 498 DENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQER 563
Cdd:COG1196 665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1924-2250 |
9.47e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.27 E-value: 9.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1924 LSSLLVKLKKVSQ-DLERQREITELKVKEFENIK-LQLQ-ENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKE 2000
Cdd:pfam15921 431 LEALLKAMKSECQgQMERQMAAIQGKNESLEKVSsLTAQlESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2001 A--NSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRA-EMTAAAEERIISATSQKEAhlNVQQIVDRHTREL--- 2074
Cdd:pfam15921 511 AieATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEAlKLQMAEKDKVIEILRQQIE--NMTQLVGQHGRTAgam 588
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2075 ---KTQVE-DLNENLLKLKEaLKTSKNRENS----LTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTS 2146
Cdd:pfam15921 589 qveKAQLEkEINDRRLELQE-FKILKDKKDAkireLEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRN 667
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2147 GLQG-----KPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDlkpmkekNAKEELIRWEEGKKWQAKIE-GIRNKLKEKE 2220
Cdd:pfam15921 668 ELNSlsedyEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELE-------QTRNTLKSMEGSDGHAMKVAmGMQKQITAKR 740
|
330 340 350
....*....|....*....|....*....|
gi 767975378 2221 GEVFTLTKQLNTLKDLFAKADKEKLTLQRK 2250
Cdd:pfam15921 741 GQIDALQSKIQFLEEAMTNANKEKHFLKEE 770
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
75-486 |
1.13e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 75 KAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEE 154
Cdd:TIGR02168 684 EKIEELEEKIAELEKALAELRKELEE------------LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 155 AENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEV 234
Cdd:TIGR02168 752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 235 QNQEMRKNLEESVQEMEKMTDEynrMKAIVHQtdnvIDQLKKENDHYQLQVQELTDLLKSKNEEddpiMVAVNAKVEEWK 314
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELSED---IESLAAE----IEELEELIEELESELEALLNERASLEEA----LALLRSELEELS 900
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 315 LILSSKDDEIIEYQQMLHNLREKLKNAQLDadksnvmaLQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQR 394
Cdd:TIGR02168 901 EELRELESKRSELRRELEELREKLAQLELR--------LEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 395 NkgastlsqqthmkiqstLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIkncknqiki 474
Cdd:TIGR02168 973 R-----------------LKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI--------- 1026
|
410
....*....|..
gi 767975378 475 rDREIEILTKEI 486
Cdd:TIGR02168 1027 -DREARERFKDT 1037
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1350-2141 |
1.27e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 50.74 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1350 EMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELE 1429
Cdd:pfam02463 202 LKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEK 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1430 KNEMELKVEVSKLREIS----DIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATAL 1505
Cdd:pfam02463 282 KLQEEELKLLAKEEEELkselLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEEL 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1506 GKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQL--QND 1583
Cdd:pfam02463 362 EKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEesIEL 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1584 KLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNRELVKDKEEIKYLN 1663
Cdd:pfam02463 442 KQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1664 NIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPL-PNQLEI 1742
Cdd:pfam02463 522 GRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIaVLEIDP 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1743 ALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKEMEPKSHHTL 1822
Cdd:pfam02463 602 ILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQEL 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1823 KIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSPTPVP 1902
Cdd:pfam02463 682 QEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEE 761
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1903 TNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLD 1982
Cdd:pfam02463 762 KEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALE 841
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1983 QSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRA-------LLELRAEMTAAAEERIISATS 2055
Cdd:pfam02463 842 LKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEkekeekkELEEESQKLNLLEEKENEIEE 921
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2056 QKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNN----ELQKKQKAYNKILREKEEID 2131
Cdd:pfam02463 922 RIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLmaieEFEEKEERYNKDELEKERLE 1001
|
810
....*....|
gi 767975378 2132 QENDELKRQI 2141
Cdd:pfam02463 1002 EEKKKLIRAI 1011
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1075-1812 |
1.35e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1075 LQELENKEKKLKNLEDSLEDYNRKFAVIRHQ--QSLLYKEYLSEKET-----WKTESKTIKEEKRKLEDQVQQDAIKVKE 1147
Cdd:TIGR02168 178 ERKLERTRENLDRLEDILNELERQLKSLERQaeKAERYKELKAELRElelalLVLRLEELREELEELQEELKEAEEELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1148 YNNLLNALQMDSDEMKKILAENSRKITVLQvneKSLIRQYTTLVELERQLRKENEKQKNeLLSMEAEVCEKIGCLQRFKE 1227
Cdd:TIGR02168 258 LTAELQELEEKLEELRLEVSELEEEIEELQ---KELYALANEISRLEQQKQILRERLAN-LERQLEELEAQLEELESKLD 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1228 MAIFKIAALQKVVDnsVSLSELELANKQYNELTAKYRDILQKdnmLVQRTSNLEHLECENISLKEQVESINKELEITKEK 1307
Cdd:TIGR02168 334 ELAEELAELEEKLE--ELKEELESLEAELEELEAELEELESR---LEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1308 LHTIEQAWE--QETKLGNESSMDKAKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQME------- 1378
Cdd:TIGR02168 409 LERLEDRRErlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAErelaqlq 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1379 ------ERNFELETKFAELTKINLDAQKVEQMLRDELADSVS------KAVSDADRQRILELE-KNEMELKVEVSKLRE- 1444
Cdd:TIGR02168 489 arldslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyeAAIEAALGGRLQAVVvENLNAAKKAIAFLKQn 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1445 ---------ISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSdEKSLIAKLHQHNVSLQLSEATALGK-------- 1507
Cdd:TIGR02168 569 elgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL-RKALSYLLGGVLVVDDLDNALELAKklrpgyri 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1508 -------------------------------LESITSKLQKMEAYNLRLEQKLDEKEQALYyarlEGRNRAKHLRQTIQS 1556
Cdd:TIGR02168 648 vtldgdlvrpggvitggsaktnssilerrreIEELEEKIEELEEKIAELEKALAELRKELE----ELEEELEQLRKELEE 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1557 LRRQFSGALP-----LAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKV 1631
Cdd:TIGR02168 724 LSRQISALRKdlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1632 I--NWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFD 1709
Cdd:TIGR02168 804 AldELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1710 RQQNEILNAAQKFEEATGSIpdpslplpNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESAL--RLAEQNILSRDK 1787
Cdd:TIGR02168 884 SLEEALALLRSELEELSEEL--------RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLqeRLSEEYSLTLEE 955
|
810 820
....*....|....*....|....*
gi 767975378 1788 VINELRLRLPATAEREKLIAELGRK 1812
Cdd:TIGR02168 956 AEALENKIEDDEEEARRRLKRLENK 980
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
119-458 |
1.54e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.45 E-value: 1.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 119 QLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLlsrr 198
Cdd:TIGR02169 199 QLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLL---- 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 199 gedsdyrSQLSKKNYELIQylDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKEN 278
Cdd:TIGR02169 275 -------EELNKKIKDLGE--EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREI 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 279 DHYQLQVQELTDLLKSKNEEDDPIMV---AVNAKVEEWKlilsskdDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQ 355
Cdd:TIGR02169 346 EEERKRRDKLTEEYAELKEELEDLRAeleEVDKEFAETR-------DELKDYREKLEKLKREINELKRELDRLQEELQRL 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 356 GIQERD--SQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEAD 433
Cdd:TIGR02169 419 SEELADlnAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
|
330 340
....*....|....*....|....*...
gi 767975378 434 AR---EKDKELVEALKRLKDYESGVYGL 458
Cdd:TIGR02169 499 ARaseERVRGGRAVEEVLKASIQGVHGT 526
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1637-2254 |
1.61e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 1.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1637 KIEELRLQELKLNRELVKDKEEIKylnniiSEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEIL 1716
Cdd:PTZ00121 1213 KAEEARKAEDAKKAEAVKKAEEAK------KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKA 1286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1717 NAAQKFEEATGSIPDPSLPLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRL 1796
Cdd:PTZ00121 1287 EEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKA 1366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1797 PA----TAEREKLIAELGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQR--EIVKKHEEdlhi 1870
Cdd:PTZ00121 1367 EAaekkKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKadEAKKKAEE---- 1442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1871 lhhrlelqadsslnkfKQTAWDLMKQSPTPvptnkhfiRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVK 1950
Cdd:PTZ00121 1443 ----------------AKKADEAKKKAEEA--------KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKK 1498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1951 EFENIKLQLQENHEDEVKKVKAevedlKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKA 2030
Cdd:PTZ00121 1499 ADEAKKAAEAKKKADEAKKAEE-----AKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAE 1573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2031 LSRALLELRAEMTAAAEE-RIISATSQKEAHLNVQQIVDRHTRELKTQVEDLNE--------NLLKLKEALKTSKNRENS 2101
Cdd:PTZ00121 1574 EDKNMALRKAEEAKKAEEaRIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKaeeekkkvEQLKKKEAEEKKKAEELK 1653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2102 LTDNLNDLNNELQKKQKAYNKilREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRK---VKKLENQLEGK 2178
Cdd:PTZ00121 1654 KAEEENKIKAAEEAKKAEEDK--KKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKaeeLKKAEEENKIK 1731
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975378 2179 VEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEgirnKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKLKTT 2254
Cdd:PTZ00121 1732 AEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLK----KEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDI 1803
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
93-374 |
1.96e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 50.32 E-value: 1.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 93 KLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKK 172
Cdd:COG1196 217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 173 NEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEK 252
Cdd:COG1196 297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 253 MTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDL---LKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQ 329
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERlerLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 767975378 330 MLHNLREKLKNA--QLDADKSNVMALQQGIQERDSQIKMLTEQVEQY 374
Cdd:COG1196 457 EEEALLELLAELleEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
34-428 |
3.12e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 3.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 34 KVEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfl 113
Cdd:PTZ00121 1565 KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE------------- 1631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 114 RNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKqidsqKET 193
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-----AEE 1706
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 194 LLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKievQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQ 273
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK---KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 274 -LKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMlhnLREKLKNAQLDADKSNVMA 352
Cdd:PTZ00121 1784 eLDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM---QLEEADAFEKHKFNKNNEN 1860
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975378 353 LQQGIQERDSQIKmlTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAE 428
Cdd:PTZ00121 1861 GEDGNKEADFNKE--KDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETRE 1934
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1909-2234 |
3.38e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 3.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1909 RLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEvKKVKAEVEDLKYLLDQSQKES 1988
Cdd:TIGR02169 675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE-EKLKERLEELEEDLSSLEQEI 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1989 QCLKSELQ--AQKEANSRAPTTTMRNLVERLKSQLALKEKQQK-ALSRALLELRAEMTAAAE--ERIISATSQKEAHLN- 2062
Cdd:TIGR02169 754 ENVKSELKelEARIEELEEDLHKLEEALNDLEARLSHSRIPEIqAELSKLEEEVSRIEARLReiEQKLNRLTLEKEYLEk 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2063 -----VQQIVDRHTR--ELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQEND 2135
Cdd:TIGR02169 834 eiqelQEQRIDLKEQikSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIE 913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2136 ELKRQIKRLTSGLQG-----KPLTDNKQSLIEE---------LQRKVKKLENQLEgKVEEVDLKPMKEknakeelirWEE 2201
Cdd:TIGR02169 914 KKRKRLSELKAKLEAleeelSEIEDPKGEDEEIpeeelsledVQAELQRVEEEIR-ALEPVNMLAIQE---------YEE 983
|
330 340 350
....*....|....*....|....*....|...
gi 767975378 2202 GKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLK 2234
Cdd:TIGR02169 984 VLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
153-508 |
3.56e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 3.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 153 EEAENENSKLRRENKRLKKKNEQLcQDIIDYQKQidsQKETLLSRRGEDSDYRSQLSKK-NYELIQYLDEIQTLTEANEK 231
Cdd:TIGR02169 166 AEFDRKKEKALEELEEVEENIERL-DLIIDEKRQ---QLERLRREREKAERYQALLKEKrEYEGYELLKEKEALERQKEA 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 232 IEVQNQEMRKNLEESVQEMEKMTDEYNRMkaivhqtdnvidqlkkendhyqlqVQELTDLLKSKNEEDDPIMVAVNAKVE 311
Cdd:TIGR02169 242 IERQLASLEEELEKLTEEISELEKRLEEI------------------------EQLLEELNKKIKDLGEEEQLRVKEKIG 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 312 EWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKsnvmaLQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNE 391
Cdd:TIGR02169 298 ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK-----LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 392 LQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEI------ 465
Cdd:TIGR02169 373 LEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKaleikk 452
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 767975378 466 ------KNCKNQIKIRDR------EIEILTKEINKLELKISDFLDENEALRERVG 508
Cdd:TIGR02169 453 qewkleQLAADLSKYEQElydlkeEYDRVEKELSKLQRELAEAEAQARASEERVR 507
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1910-2266 |
5.80e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.53 E-value: 5.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1910 LAEMEQTVAEQD---DSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQK 1986
Cdd:TIGR02169 179 LEEVEENIERLDliiDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1987 ESQCLKSELqAQKEANSRAPTTTMRNLVE----RLKSQLALKEKQQKALSRALLELRAEMTAAAEERiisatSQKEAHLN 2062
Cdd:TIGR02169 259 EISELEKRL-EEIEQLLEELNKKIKDLGEeeqlRVKEKIGELEAEIASLERSIAEKERELEDAEERL-----AKLEAEID 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2063 VQQivdRHTRELKTQVEDLNENLLKLKEALKTSKnrensltDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIk 2142
Cdd:TIGR02169 333 KLL---AEIEELEREIEEERKRRDKLTEEYAELK-------EELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI- 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2143 rltsglqgKPLTDNKQSLIEELQRKVKKLEnQLEGKVEEVDLKPMKEKNAKEELIrwEEGKKWQAKIEGIRNKLKEKEGE 2222
Cdd:TIGR02169 402 --------NELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELEEEKEDKA--LEIKKQEWKLEQLAADLSKYEQE 470
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 767975378 2223 VFTLTKQLNTLKDLFAKADKEkltLQRKLKTTGMTVDQVLGIRA 2266
Cdd:TIGR02169 471 LYDLKEEYDRVEKELSKLQRE---LAEAEAQARASEERVRGGRA 511
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
1932-2248 |
8.61e-05 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 47.83 E-value: 8.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1932 KKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQS----QKESQCLKSELQAQKEANSRAPT 2007
Cdd:pfam09731 121 KSEQEKEKALEEVLKEAISKAESATAVAKEAKDDAIQAVKAHTDSLKEASDTAeisrEKATDSALQKAEALAEKLKEVIN 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2008 TTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVdrhtRELKTQVEDLNENLlk 2087
Cdd:pfam09731 201 LAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASERIVFQ----QELVSIFPDIIPVL-- 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2088 lKEALKTSKNRENSLTD----NLNDLNNELQKKQKAYNKilREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQsLIEE 2163
Cdd:pfam09731 275 -KEDNLLSNDDLNSLIAhahrEIDQLSKKLAELKKREEK--HIERALEKQKEELDKLAEELSARLEEVRAADEAQ-LRLE 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2164 LQRKV--------KKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKD 2235
Cdd:pfam09731 351 FEREReeiresyeEKLRTELERQAEAHEEHLKDVLVEQEIELQREFLQDIKEKVEEERAGRLLKLNELLANLKGLEKATS 430
|
330
....*....|...
gi 767975378 2236 LFAKADKEKLTLQ 2248
Cdd:pfam09731 431 SHSEVEDENRKAQ 443
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
990-1868 |
1.20e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.74 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 990 AQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRqsegsnvvfkgidlpdgiapssaSIINSQNE 1069
Cdd:TIGR02168 225 LELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR-----------------------LEVSELEE 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1070 YLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQsllyKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYN 1149
Cdd:TIGR02168 282 EIEELQKELYALANEISRLEQQKQILRERLANLERQL----EELEAQLEELESKLDELAEELAELEEKLEELKEELESLE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1150 NLLNALQMDSDEMKKILAEnsrkitvlqvneksLIRQYTTLVELERQLRKENEKQKNELLSMEAEvcekigclqrfkema 1229
Cdd:TIGR02168 358 AELEELEAELEELESRLEE--------------LEEQLETLRSKVAQLELQIASLNNEIERLEAR--------------- 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1230 ifkIAALQKVVDNSVSLSELELANKQYNELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLH 1309
Cdd:TIGR02168 409 ---LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1310 TIEQAWEQ-ETKLGNESSMDKAKKSITN------------SDIVSISKK------------ITMLEMKELNERQRAEHCQ 1364
Cdd:TIGR02168 486 QLQARLDSlERLQENLEGFSEGVKALLKnqsglsgilgvlSELISVDEGyeaaieaalggrLQAVVVENLNAAKKAIAFL 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1365 KMYEHLRTSlkqmeernfeletkFAELTKINLDAQKVEQMLRDELADSVskavsdadRQRILELEKNEMELKVEVSKLRE 1444
Cdd:TIGR02168 566 KQNELGRVT--------------FLPLDSIKGTEIQGNDREILKNIEGF--------LGVAKDLVKFDPKLRKALSYLLG 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1445 ISDIARRqveILNAQQQSRDKEVESLRMQLLDYQAQSDekSLIAKLHQHNVSLQLSEATALGKLEsitSKLQKMEAYNLR 1524
Cdd:TIGR02168 624 GVLVVDD---LDNALELAKKLRPGYRIVTLDGDLVRPG--GVITGGSAKTNSSILERRREIEELE---EKIEELEEKIAE 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1525 LEQKLDEKEQALYyarlEGRNRAKHLRQTIQSLRRQFSGALplaqqekfsktmIQLQNDKLKIMQEMKNSQQEHRNMENK 1604
Cdd:TIGR02168 696 LEKALAELRKELE----ELEEELEQLRKELEELSRQISALR------------KDLARLEAEVEQLEERIAQLSKELTEL 759
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1605 TLEMELKLKGLEELISTLKDTKGaqkvinwhmKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQqn 1684
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEA---------EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES-- 828
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1685 kfHEERQMAWDQREVDLERQLDifdrqqneilNAAQKFEEATGSIpdpslplpNQLEIALRKIKENIRIILETRAtckSL 1764
Cdd:TIGR02168 829 --LERRIAATERRLEDLEEQIE----------ELSEDIESLAAEI--------EELEELIEELESELEALLNERA---SL 885
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1765 EEKLKEKESALRLAEQNILSRDKVINELRlrlpatAEREKLIAELGRKEMEpkshhtLKIAHQTIANMQARLNQK----E 1840
Cdd:TIGR02168 886 EEALALLRSELEELSEELRELESKRSELR------RELEELREKLAQLELR------LEGLEVRIDNLQERLSEEysltL 953
|
890 900
....*....|....*....|....*...
gi 767975378 1841 EVLKKYQRLLEKAREEQREIVKKHEEDL 1868
Cdd:TIGR02168 954 EEAEALENKIEDDEEEARRRLKRLENKI 981
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1656-2204 |
1.38e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.44 E-value: 1.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1656 KEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQRevdLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLP 1735
Cdd:PTZ00121 1030 EELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEG---LKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKT 1106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1736 LPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKEME 1815
Cdd:PTZ00121 1107 ETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE 1186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1816 PKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQT--AWDL 1893
Cdd:PTZ00121 1187 VRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEArmAHFA 1266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1894 MKQSPTPVPTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAE 1973
Cdd:PTZ00121 1267 RRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE 1346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1974 VedlkylldqSQKESQCLKSELQAQKEansRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISA 2053
Cdd:PTZ00121 1347 A---------AKAEAEAAADEAEAAEE---KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAA 1414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2054 TSQKEAHlnvqqivdrhtrELKTQVEDLNenllKLKEALKTSKNRENSltdnlNDLNNELQKKQKAYNkiLREKEEIDQE 2133
Cdd:PTZ00121 1415 AAKKKAD------------EAKKKAEEKK----KADEAKKKAEEAKKA-----DEAKKKAEEAKKAEE--AKKKAEEAKK 1471
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767975378 2134 NDELKRQIKRltsglqgKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKK 2204
Cdd:PTZ00121 1472 ADEAKKKAEE-------AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK 1535
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1958-2150 |
1.69e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1958 QLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRApTTTMRNL---VERLKSQLALKEKQQKALSRA 2034
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL-ARRIRALeqeLAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2035 LLELR---AEMTAAAEER--------IISATSQKEAhLNVQQIVDRHTRELKTQVEDLNEN---LLKLKEALKTSKNREN 2100
Cdd:COG4942 99 LEAQKeelAELLRALYRLgrqpplalLLSPEDFLDA-VRRLQYLKYLAPARREQAEELRADlaeLAALRAELEAERAELE 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 767975378 2101 SLTDNLNDLNNELQKKQKAYNKIL----REKEEIDQENDELKRQIKRLTSGLQG 2150
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLarleKELAELAAELAELQQEAEELEALIAR 231
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
848-1208 |
1.83e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.97 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 848 ENLIEQLRRELVFLRSQNEIIAQEFLIKEAECRNADIELEHHRSQAEQnefLSRELIEKERDLERSRTVIAKFQNKLKEL 927
Cdd:TIGR02168 669 NSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQ---LRKELEELSRQISALRKDLARLEAEVEQL 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 928 VEENKQLEegmKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNaiesknaegifdaslhLKAQVDQLTGRNEELRQELR 1007
Cdd:TIGR02168 746 EERIAQLS---KELTELEAEIEELEERLEEAEEELAEAEAEIEE----------------LEAQIEQLKEELKALREALD 806
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1008 ESRKEAINYSQQLAKANLKIDHLEKETSLLRQSegsnvvfkgidlpdgiAPSSASIINSQNEYLIHLLQELENKEKKLKN 1087
Cdd:TIGR02168 807 ELRAELTLLNEEAANLRERLESLERRIAATERR----------------LEDLEEQIEELSEDIESLAAEIEELEELIEE 870
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1088 LEDSLEdynrKFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILA 1167
Cdd:TIGR02168 871 LESELE----ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 767975378 1168 ENsrkitvLQVNEKSLIRQYTTLVELERQLRKENEKQKNEL 1208
Cdd:TIGR02168 947 EE------YSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
17-277 |
2.14e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.60 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 17 DLPRQEELADNLLISLSKvEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLEN 96
Cdd:TIGR02169 234 ALERQKEAIERQLASLEE-ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 97 ELEMAQQSAGGR-----DTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKK 171
Cdd:TIGR02169 313 KERELEDAEERLakleaEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 172 KNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEME 251
Cdd:TIGR02169 393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELY 472
|
250 260
....*....|....*....|....*.
gi 767975378 252 KMTDEYNRMKAIVHQTDNVIDQLKKE 277
Cdd:TIGR02169 473 DLKEEYDRVEKELSKLQRELAEAEAQ 498
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1257-1597 |
2.19e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 46.66 E-value: 2.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1257 NELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEiTKEKLHTIEQAWEQEtklgnessMDKakksitN 1336
Cdd:pfam17380 268 NEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVE-RRRKLEEAEKARQAE--------MDR------Q 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1337 SDIVSISKKITMLEMKELnERQRAEHCQKMYEHLRtslkqMEERNFELEtKFAELTKINLDAQKVEQMLRDELADSVSKA 1416
Cdd:pfam17380 333 AAIYAEQERMAMEREREL-ERIRQEERKRELERIR-----QEEIAMEIS-RMRELERLQMERQQKNERVRQELEAARKVK 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1417 VSDADRQRILELEKNEMEL------KVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQlldyQAQSDEKSLIAKL 1490
Cdd:pfam17380 406 ILEEERQRKIQQQKVEMEQiraeqeEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQ----EEERKRKKLELEK 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1491 HQHNVSLQLSEATALGKLESITSKLQKMEAYNLR--LEQKLDEKEQALYYArlEGRNRAKHLRQTIQSL--RRQFSGALP 1566
Cdd:pfam17380 482 EKRDRKRAEEQRRKILEKELEERKQAMIEEERKRklLEKEMEERQKAIYEE--ERRREAEEERRKQQEMeeRRRIQEQMR 559
|
330 340 350
....*....|....*....|....*....|.
gi 767975378 1567 LAQQEKFSKTMIQLQNDKLKIMQEMKNSQQE 1597
Cdd:pfam17380 560 KATEERSRLEAMEREREMMRQIVESEKARAE 590
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1965-2174 |
2.21e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 46.83 E-value: 2.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1965 DEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNL-VERLKSQLALKEKQQKALSRALLELRAEMT 2043
Cdd:PRK11281 73 DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLsLRQLESRLAQTLDQLQNAQNDLAEYNSQLV 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2044 AA--AEERIISATSQkeahlNVQQivdrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTdnlnDLNNELQKKQKAYN 2121
Cdd:PRK11281 153 SLqtQPERAQAALYA-----NSQR-----LQQIRNLLKGGKVGGKALRPSQRVLLQAEQALL----NAQNDLQRKSLEGN 218
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 767975378 2122 KILREKEEidQENDELKRQIKRLTSGLQgkpltdNKQSLI-----EELQRKVKKLENQ 2174
Cdd:PRK11281 219 TQLQDLLQ--KQRDYLTARIQRLEHQLQ------LLQEAInskrlTLSEKTVQEAQSQ 268
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1660-2178 |
2.40e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 46.65 E-value: 2.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1660 KYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKfeeatgsipdpslplPNQ 1739
Cdd:pfam15921 74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR---------------ESQ 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1740 LEIALRKIKENIRIILETRATCKslEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAE-------REKLIAELGRK 1812
Cdd:pfam15921 139 SQEDLRNQLQNTVHELEAAKCLK--EDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEasgkkiyEHDSMSTMHFR 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1813 EMEPKSHHTLKIAHQTIANMQARLNQKEEVLK--------KYQRLLEKAREEQREIVKKHEEDLHILHHRLElQADSSLN 1884
Cdd:pfam15921 217 SLGSAISKILRELDTEISYLKGRIFPVEDQLEalksesqnKIELLLQQHQDRIEQLISEHEVEITGLTEKAS-SARSQAN 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1885 KFKQTAWDLMKQSPTpvpTNKHFIR-LAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQE-- 1961
Cdd:pfam15921 296 SIQSQLEIIQEQARN---QNSMYMRqLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQes 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1962 -NHEDEVKKVkaevedlkyLLDQSQKEsqclkSELQAQKEANSRAPTTTMRN--LVERLKSQLALKEKQQKALSRALLEL 2038
Cdd:pfam15921 373 gNLDDQLQKL---------LADLHKRE-----KELSLEKEQNKRLWDRDTGNsiTIDHLRRELDDRNMEVQRLEALLKAM 438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2039 RAEMTAAAEERIISATSQKEAHLNVQQivdrhtreLKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQK 2118
Cdd:pfam15921 439 KSECQGQMERQMAAIQGKNESLEKVSS--------LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2119 AynkilrekeeIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGK 2178
Cdd:pfam15921 511 A----------IEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEK 560
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
106-373 |
3.05e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 3.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 106 GGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEK-EKKVNEQLALRNE------EAENENSKLRRENKRLKKKNEQLCQ 178
Cdd:TIGR02169 658 GSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSlQSELRRIENRLDElsqelsDASRKIGEIEKEIEQLEQEEEKLKE 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 179 DIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTL--TEANEKIEVQNQEMRKnLEESVQEMEKMTDE 256
Cdd:TIGR02169 738 RLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLeaRLSHSRIPEIQAELSK-LEEEVSRIEARLRE 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 257 YNRMKAIVHQTDNVIDQLKKEndhyqlqVQELTDLLKSKNEEddpimvaVNAKVEEWKLILSSKDDEIIEYQQMLHNLRE 336
Cdd:TIGR02169 817 IEQKLNRLTLEKEYLEKEIQE-------LQEQRIDLKEQIKS-------IEKEIENLNGKKEELEEELEELEAALRDLES 882
|
250 260 270
....*....|....*....|....*....|....*....
gi 767975378 337 KLKNAQLDAD--KSNVMALQQGIQERDSQIKMLTEQVEQ 373
Cdd:TIGR02169 883 RLGDLKKERDelEAQLRELERKIEELEAQIEKKRKRLSE 921
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1161-1689 |
4.22e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.83 E-value: 4.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1161 EMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRK------ENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIA 1234
Cdd:PRK03918 197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEElkeeieELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1235 ALQKVVDNsvsLSELELANKQYNELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQA 1314
Cdd:PRK03918 277 ELEEKVKE---LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKR 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1315 WEQETKLGNESSMDKAKKsitnSDIVSISKKITMLEMKELNE-----RQRAEHCQKMYEHLRTSLKQMEERNFELETKFA 1389
Cdd:PRK03918 354 LEELEERHELYEEAKAKK----EELERLKKRLTGLTPEKLEKeleelEKAKEEIEEEISKITARIGELKKEIKELKKAIE 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1390 ELTKIN----LDAQKVEQMLRDELADSVSKAVSDAdRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDK 1465
Cdd:PRK03918 430 ELKKAKgkcpVCGRELTEEHRKELLEEYTAELKRI-EKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKEL 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1466 EVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALyyaRLEGRN 1545
Cdd:PRK03918 509 EEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL---EELGFE 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1546 RAKHLRQTIQSLrrqfsgalplaqqEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDT 1625
Cdd:PRK03918 586 SVEELEERLKEL-------------EPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEL 652
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767975378 1626 kgaqKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEE 1689
Cdd:PRK03918 653 ----EKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE 712
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
87-563 |
4.51e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.88 E-value: 4.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 87 LKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDREL----EDMEKELEKEKKVNEQLALRNEEAENENSKL 162
Cdd:pfam15921 236 LKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEItgltEKASSARSQANSIQSQLEIIQEQARNQNSMY 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 163 RRENKRLKKKNEQLCQDIIDYQKQIDSQKETLlsrrgedsdyRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKN 242
Cdd:pfam15921 316 MRQLSDLESTVSQLRSELREAKRMYEDKIEEL----------EKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 243 LEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMvavnakveewklilsskdd 322
Cdd:pfam15921 386 LHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM------------------- 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 323 eiiEYQqmlhnlreklknaqldadksnvMALQQGIQERDSQIKMLTEQVEQyTKEMEKNtcIIEDLknelqrnkgasTLS 402
Cdd:pfam15921 447 ---ERQ----------------------MAAIQGKNESLEKVSSLTAQLES-TKEMLRK--VVEEL-----------TAK 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 403 QQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEIL 482
Cdd:pfam15921 488 KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEIL 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 483 TKEI-NKLELKISDFLDENEALRERVGLEPKT---MIDLTEFRNSKHLKQQQYRAenqiLLKEIESLEEERLDLK----- 553
Cdd:pfam15921 568 RQQIeNMTQLVGQHGRTAGAMQVEKAQLEKEIndrRLELQEFKILKDKKDAKIRE----LEARVSDLELEKVKLVnagse 643
|
490
....*....|..
gi 767975378 554 --KKIRQMAQER 563
Cdd:pfam15921 644 rlRAVKDIKQER 655
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1517-2243 |
4.99e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.73 E-value: 4.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1517 KMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQ 1596
Cdd:pfam02463 207 KKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEE 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1597 EHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSL 1676
Cdd:pfam02463 287 ELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQE 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1677 EEEIVQQN---KFHEERQMAwDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLPNQLEIALRKIKENIRI 1753
Cdd:pfam02463 367 KLEQLEEEllaKKKLESERL-SSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGK 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1754 ILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKEMEPKSHHTLKIAHQT---IA 1830
Cdd:pfam02463 446 LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVggrII 525
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1831 NMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADS-----SLNKFKQTAWDLMKQSPTPVPTNK 1905
Cdd:pfam02463 526 SAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGarklrLLIPKLKLPLKSIAVLEIDPILNL 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1906 HFIRLAEMEQTVAEQDDSLSSLLVKLKkvsqdlERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQ 1985
Cdd:pfam02463 606 AQLDKATLEADEDDKRAKVVEGILKDT------ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1986 KESQCLKSELQA---------QKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERI------ 2050
Cdd:pfam02463 680 ELQEKAESELAKeeilrrqleIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEksrlkk 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2051 ------ISATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKnRENSLTDNLNDLNNELQKKQKAYNKIL 2124
Cdd:pfam02463 760 eekeeeKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK-EEAELLEEEQLLIEQEEKIKEEELEEL 838
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2125 REKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKK 2204
Cdd:pfam02463 839 ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENE 918
|
730 740 750
....*....|....*....|....*....|....*....
gi 767975378 2205 WQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKE 2243
Cdd:pfam02463 919 IEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEE 957
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
885-1679 |
6.47e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 6.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 885 ELEHHRSQAEQNEFLSRELIEKERDLERSRTVIAKFQNKLKELVE--------ENKQLEEGMKEI---LQAIKEMQKDPD 953
Cdd:TIGR02169 178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREyegyellkEKEALERQKEAIerqLASLEEELEKLT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 954 VKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKE 1033
Cdd:TIGR02169 258 EEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1034 TSLLRQSEGSNVVFKgidlpdgiAPSSASIINSQNEYLIhLLQELENKEKKLKNLEDSLEDYNRKFavirhqqsllyKEY 1113
Cdd:TIGR02169 338 IEELEREIEEERKRR--------DKLTEEYAELKEELED-LRAELEEVDKEFAETRDELKDYREKL-----------EKL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1114 LSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVEL 1193
Cdd:TIGR02169 398 KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1194 ERQLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSELELANKQYNELTAKYR--DILQKDN 1271
Cdd:TIGR02169 478 YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRlnNVVVEDD 557
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1272 MLVQRTsnLEHLECENISLK-----EQVESINKELEITKEK--------LHTIEQAWEQETK--LGNE---SSMDKAKKS 1333
Cdd:TIGR02169 558 AVAKEA--IELLKRRKAGRAtflplNKMRDERRDLSILSEDgvigfavdLVEFDPKYEPAFKyvFGDTlvvEDIEAARRL 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1334 ITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELetkfaeltKINLDAQKVEQMLRDELADSV 1413
Cdd:TIGR02169 636 MGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGL--------KRELSSLQSELRRIENRLDEL 707
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1414 SKAVSDADRQrILELEKNEMELKVEVSKLREisdiarrQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSliAKLHQH 1493
Cdd:TIGR02169 708 SQELSDASRK-IGEIEKEIEQLEQEEEKLKE-------RLEELEEDLSSLEQEIENVKSELKELEARIEELE--EDLHKL 777
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1494 NVSLQLSEATALG-KLESITSKLQKMEAYNLRLEQKLDEKEQALyYARLEGRNRAKHLRQTIQSLRRQFSgalplAQQEK 1572
Cdd:TIGR02169 778 EEALNDLEARLSHsRIPEIQAELSKLEEEVSRIEARLREIEQKL-NRLTLEKEYLEKEIQELQEQRIDLK-----EQIKS 851
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1573 FSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMElklKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNREL 1652
Cdd:TIGR02169 852 IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928
|
810 820
....*....|....*....|....*..
gi 767975378 1653 VKDKeeikylnniISEYERTISSLEEE 1679
Cdd:TIGR02169 929 LEEE---------LSEIEDPKGEDEEI 946
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
217-570 |
1.00e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.67 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 217 QYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEynRMKAIVHQtdnvidQLKKEndhyqLQVQELTDLLKSKN 296
Cdd:TIGR02169 167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE--REKAERYQ------ALLKE-----KREYEGYELLKEKE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 297 EEDDPImVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLK--NAQLDADKSNVM-ALQQGIQERDSQIKMLTEQVEQ 373
Cdd:TIGR02169 234 ALERQK-EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEelNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIAE 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 374 YTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYES 453
Cdd:TIGR02169 313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 454 GVYGLEDAVVEIKNCKNQIKIRDREIEI----LTKEINKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQ 529
Cdd:TIGR02169 393 KLEKLKREINELKRELDRLQEELQRLSEeladLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELY 472
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 767975378 530 QYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATS 570
Cdd:TIGR02169 473 DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE 513
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1289-1856 |
1.02e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.54 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1289 SLKEQVE------SINKELEITK--EKLHTIEQAWEQETKLGNESSMDKAKKSITNSDIVSISKKITMLEMKELNERQRA 1360
Cdd:COG1196 204 PLERQAEkaeryrELKEELKELEaeLLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1361 EHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELADsvskavsdaDRQRILELEKNEMELKVEVS 1440
Cdd:COG1196 284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE---------LEEELEELEEELEEAEEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1441 KLRE-ISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKME 1519
Cdd:COG1196 355 EAEAeLAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1520 AYNLRLEQKLDE-KEqalyyARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEmknsQQEH 1598
Cdd:COG1196 435 EEEEEEEEALEEaAE-----EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA----DYEG 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1599 RNMENKTLEMELKLKGLEELISTL------------------------KDTKGAQKVINWHMKIEELRLQELKLNRElvk 1654
Cdd:COG1196 506 FLEGVKAALLLAGLRGLAGAVAVLigveaayeaaleaalaaalqnivvEDDEVAAAAIEYLKAAKAGRATFLPLDKI--- 582
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1655 DKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSl 1734
Cdd:COG1196 583 RARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS- 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1735 plpnqleIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKEM 1814
Cdd:COG1196 662 -------LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 767975378 1815 EPKSHHTLKIAHQTIANMQARL--NQKEEVLKKYQRLLEKAREE 1856
Cdd:COG1196 735 EELLEELLEEEELLEEEALEELpePPDLEELERELERLEREIEA 778
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1580-1987 |
1.05e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.67 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1580 LQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDtkgaqkvinwhmKIEELRLQELKLNRELVKDKEEI 1659
Cdd:TIGR02169 693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE------------RLEELEEDLSSLEQEIENVKSEL 760
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1660 KYLNNIISEYERTISSLEEEIvqqnkfheerqmawdqreVDLERQLDifDRQQNEILNAAQKFEEATGSIpdpslplpnq 1739
Cdd:TIGR02169 761 KELEARIEELEEDLHKLEEAL------------------NDLEARLS--HSRIPEIQAELSKLEEEVSRI---------- 810
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1740 leialRKIKENIRIILETRATCK-SLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAERekliaelgrkemepks 1818
Cdd:TIGR02169 811 -----EARLREIEQKLNRLTLEKeYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE---------------- 869
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1819 hhtlkiahqtIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEdlhilhhrlelqADSSLNKFKQTAWDLMKQSP 1898
Cdd:TIGR02169 870 ----------LEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE------------LEAQIEKKRKRLSELKAKLE 927
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1899 TPVPTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEnHEDEVKKVKAEVEDLK 1978
Cdd:TIGR02169 928 ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE-LKEKRAKLEEERKAIL 1006
|
....*....
gi 767975378 1979 YLLDQSQKE 1987
Cdd:TIGR02169 1007 ERIEEYEKK 1015
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
113-488 |
1.13e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 44.24 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 113 LRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKE 192
Cdd:TIGR04523 354 SESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKE 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 193 TLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVID 272
Cdd:TIGR04523 434 TIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVK 513
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 273 QLKKENDHYQLQVQELTDLLKSKNE-----EDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADK 347
Cdd:TIGR04523 514 DLTKKISSLKEKIEKLESEKKEKESkisdlEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ 593
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 348 --SNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAER 425
Cdd:TIGR04523 594 keKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKT 673
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767975378 426 TA----ELAEADAREKDKELVEALKRLKDYeSGVYGLEDAVVEIKNCKNQIKIRDREIEILTKEINK 488
Cdd:TIGR04523 674 KIddiiELMKDWLKELSLHYKKYITRMIRI-KDLPKLEEKYKEIEKELKKLDEFSKELENIIKNFNK 739
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
130-176 |
1.31e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 43.67 E-value: 1.31e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 767975378 130 ELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQL 176
Cdd:PRK03992 2 RLEALEERNSELEEQIRQLELKLRDLEAENEKLERELERLKSELEKL 48
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1913-2133 |
1.31e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1913 MEQTVAEQDDSLSSLLVKLKKVSQDLER-QREITELKVK-------EFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQS 1984
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEaEAALEEFRQKnglvdlsEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1985 QKEsqcLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMtAAAEERIISATSQKEAHLNVQ 2064
Cdd:COG3206 246 RAQ---LGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQI-AALRAQLQQEAQRILASLEAE 321
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767975378 2065 QivdrhtRELKTQVEDLNENLLKLKEALKTSKNREnsltDNLNDLNNELQKKQKAYNKILREKEEIDQE 2133
Cdd:COG3206 322 L------EALQAREASLQAQLAQLEARLAELPELE----AELRRLEREVEVARELYESLLQRLEEARLA 380
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
149-394 |
1.40e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 1.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 149 ALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNyeliqylDEIQTLTEA 228
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALE-------AELAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 229 NEKIEVQNQEMRKNLEESVQEMEKMtDEYNRMKAIVHQTDnvidqlkkendhyQLQVQELTDLLKSKNEEDDPIMVAVNA 308
Cdd:COG4942 92 IAELRAELEAQKEELAELLRALYRL-GRQPPLALLLSPED-------------FLDAVRRLQYLKYLAPARREQAEELRA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 309 KVEEwkliLSSKDDEIIEYQQMLHNLREKLKNAQLdadksnvmALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDL 388
Cdd:COG4942 158 DLAE----LAALRAELEAERAELEALLAELEEERA--------ALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225
|
....*.
gi 767975378 389 KNELQR 394
Cdd:COG4942 226 EALIAR 231
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1745-2222 |
1.49e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1745 RKIKENIRIILETRA-TCKSLEEKLKEKESALRLAEQNILSRDKVINELRL-----RLPATAEREKLIAELGRKEMEPKS 1818
Cdd:PTZ00121 1212 RKAEEARKAEDAKKAeAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMahfarRQAAIKAEEARKADELKKAEEKKK 1291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1819 HHTLKIAHQTIANMQARlnQKEEVLKKYQRLLEKAREEQR---EIVKKHEEdlhilhhrlELQADSSLNKFKQTAWDLMK 1895
Cdd:PTZ00121 1292 ADEAKKAEEKKKADEAK--KKAEEAKKADEAKKKAEEAKKkadAAKKKAEE---------AKKAAEAAKAEAEAAADEAE 1360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1896 QSPTPVPTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREitELKVKEFENIKLQLQENHEDEVKK---VKA 1972
Cdd:PTZ00121 1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKAD--ELKKAAAAKKKADEAKKKAEEKKKadeAKK 1438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1973 EVEDLKYLLDQSQKESQCLKSElQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIIS 2052
Cdd:PTZ00121 1439 KAEEAKKADEAKKKAEEAKKAE-EAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKK 1517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2053 ATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSltdnlndlnNELQKKQKAYNKILREKEEIDQ 2132
Cdd:PTZ00121 1518 AEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKA---------EEAKKAEEDKNMALRKAEEAKK 1588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2133 ENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGI 2212
Cdd:PTZ00121 1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668
|
490
....*....|
gi 767975378 2213 RNKLKEKEGE 2222
Cdd:PTZ00121 1669 KAEEDKKKAE 1678
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
2043-2243 |
1.58e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.28 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2043 TAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNK 2122
Cdd:COG3883 11 PAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2123 ILREKEEIDQENDELK-----RQIKRLTSGLQG-KPLTDNKQSLIEELQRKVKKLENQ---LEGKVEEVDLKPMKEKNAK 2193
Cdd:COG3883 91 RARALYRSGGSVSYLDvllgsESFSDFLDRLSAlSKIADADADLLEELKADKAELEAKkaeLEAKLAELEALKAELEAAK 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 767975378 2194 EELirweegkkwQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKE 2243
Cdd:COG3883 171 AEL---------EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
35-200 |
1.90e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.31 E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 35 VEVNELKSEkqenVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfLR 114
Cdd:COG2433 363 VDRDEVKAR----VIRGLSIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVER------------LE 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 115 NEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAenenSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETL 194
Cdd:COG2433 427 AEVEELEAELEEKDERIERLERELSEARSEERREIRKDREI----SRLDREIERLERELEEERERIEELKRKLERLKELW 502
|
....*..
gi 767975378 195 -LSRRGE 200
Cdd:COG2433 503 kLEHSGE 509
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
891-1156 |
1.99e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.83 E-value: 1.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 891 SQAEQNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEilqaikemqkdpdvkggetsliipsLERLV 970
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAA-------------------------LARRI 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 971 NAIESKNAEgifdaslhLKAQVDQLTGRNEELRQELRESRKEainYSQQLAKAnLKIDHLEKETSLLRQSEGSNVVfkgi 1050
Cdd:COG4942 72 RALEQELAA--------LEAELAELEKEIAELRAELEAQKEE---LAELLRAL-YRLGRQPPLALLLSPEDFLDAV---- 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1051 dlpdgiapSSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESKTIKEE 1130
Cdd:COG4942 136 --------RRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKE 207
|
250 260
....*....|....*....|....*.
gi 767975378 1131 KRKLEDQVQQDAIKVKEYNNLLNALQ 1156
Cdd:COG4942 208 LAELAAELAELQQEAEELEALIARLE 233
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
1915-2183 |
2.05e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 43.46 E-value: 2.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1915 QTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKefeniklqLQENHEDEVKKV-KAEVEDLKYLLDQSQKESQCLKS 1993
Cdd:PHA02562 163 SVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIK--------TYNKNIEEQRKKnGENIARKQNKYDELVEEAKTIKA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1994 ELqaqkeansraptttmrnlvERLKSQLALKEKQQKALSRALLELRAEMTAAAEERiisATSQKEAHLN---------VQ 2064
Cdd:PHA02562 235 EI-------------------EELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKI---EQFQKVIKMYekggvcptcTQ 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2065 QIVDrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRL 2144
Cdd:PHA02562 293 QISE--GPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEEL 370
|
250 260 270
....*....|....*....|....*....|....*....
gi 767975378 2145 TSGlqgkplTDNKQSLIEELQRKVKKLENQLEGKVEEVD 2183
Cdd:PHA02562 371 QAE------FVDNAEELAKLQDELDKIVKTKSELVKEKY 403
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1909-2152 |
2.37e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.37 E-value: 2.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1909 RLAEMEQTVAEQDDSLSSLLVKLKKVSQDL----ERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQS 1984
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELdalqERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAAL 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1985 QKESQCLKSELQAQKEANSRApTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIiSATSQKEAHLNVQ 2064
Cdd:COG4913 691 EEQLEELEAELEELEEELDEL-KGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF-AAALGDAVERELR 768
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2065 QIVDRHTRELKTQVEDLNENLLKL-KEALKTSKNRENSLTDNLNDL-----------NNELQKKQKAYNKILREKE---- 2128
Cdd:COG4913 769 ENLEERIDALRARLNRAEEELERAmRAFNREWPAETADLDADLESLpeylalldrleEDGLPEYEERFKELLNENSiefv 848
|
250 260
....*....|....*....|....*....
gi 767975378 2129 -----EIDQENDELKRQIKRLTSGLQGKP 2152
Cdd:COG4913 849 adllsKLRRAIREIKERIDPLNDSLKRIP 877
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
2125-2266 |
2.41e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.31 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2125 REKEEIDQENDELKRQIKRLtsglqgkpltdnkQSLIEELQRKVKKLENQLEGKVEEVD-----LKPMKeKNAKEELIRW 2199
Cdd:COG2433 399 REKEHEERELTEEEEEIRRL-------------EEQVERLEAEVEELEAELEEKDERIErlereLSEAR-SEERREIRKD 464
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767975378 2200 EEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKL----KTTGMTVDQVLGIRA 2266
Cdd:COG2433 465 REISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGELVPVKVVekftKEAIRRLEEEYGLKE 535
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
331-1155 |
2.63e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.12 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 331 LHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLK---NELQRNKGASTLSQQTHM 407
Cdd:TIGR02168 215 YKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlevSELEEEIEELQKELYALA 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 408 KIQSTLD----ILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYEsgvYGLEDAVVEIKNCKNQIKIRDREIEILT 483
Cdd:TIGR02168 295 NEISRLEqqkqILRERLANLERQLEELEAQLEELESKLDELAEELAELE---EKLEELKEELESLEAELEELEAELEELE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 484 KEINKLELKISDFLDENEALRERVGLEPKTMIdltefRNSKHLKQQQYRAENqiLLKEIESLEEERLDLKKKIRQMAQER 563
Cdd:TIGR02168 372 SRLEELEEQLETLRSKVAQLELQIASLNNEIE-----RLEARLERLEDRRER--LQQEIEELLKKLEEAELKELQAELEE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 564 GKRSATSGLTTEDLNLTENISQGDRISERKLDLLSLKN-MSEAQSKIRSSDKAELLHRRSSFNTPQSDQNETEENMTIGS 642
Cdd:TIGR02168 445 LEEELEELQEELERLEEALEELREELEEAEQALDAAEReLAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 643 LSRMLSeihhsVESGMHPFVpLTRLSSSMQ--VKENSTP---------ETITIREIFKAPCLQSSRNLESlVSTFSRESH 711
Cdd:TIGR02168 525 LSELIS-----VDEGYEAAI-EAALGGRLQavVVENLNAakkaiaflkQNELGRVTFLPLDSIKGTEIQG-NDREILKNI 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 712 EEINDICLFSDDCMKKVSRSHQALEKTSFVQKSnssfhgLSTASDIMQKLslRQKSAIFCQQIHENRADmdksQVATLEE 791
Cdd:TIGR02168 598 EGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD------LDNALELAKKL--RPGYRIVTLDGDLVRPG----GVITGGS 665
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 792 EQVHSQVKYADINLKEdiiksevpLQTEILKNKLKVNLpdpVSITAQSKLSQINSLENLIEQLRRELVFLRSQNEIIAQE 871
Cdd:TIGR02168 666 AKTNSSILERRREIEE--------LEEKIEELEEKIAE---LEKALAELRKELEELEEELEQLRKELEELSRQISALRKD 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 872 FLIKEAECRNAdielehhrsqAEQNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKD 951
Cdd:TIGR02168 735 LARLEAEVEQL----------EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 952 PDVKGGETSLIIPSLERLVNAIESknaegifdaslhLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLE 1031
Cdd:TIGR02168 805 LDELRAELTLLNEEAANLRERLES------------LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1032 KE-TSLLRQSEGSNVvfkgidlpdgiapsSASIINSQNEYLIHLLQELENK----EKKLKNLEDSLEDYNRKFAVIRhQQ 1106
Cdd:TIGR02168 873 SElEALLNERASLEE--------------ALALLRSELEELSEELRELESKrselRRELEELREKLAQLELRLEGLE-VR 937
|
810 820 830 840
....*....|....*....|....*....|....*....|....*....
gi 767975378 1107 SLLYKEYLSEKetWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNAL 1155
Cdd:TIGR02168 938 IDNLQERLSEE--YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
851-1690 |
2.67e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 43.13 E-value: 2.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 851 IEQLRRELVFLRSQNEIIAqeflIKEAECRNADIELEHHRSQAEQNEFLSRELIEKErdlersrtviakFQNKLKELVEE 930
Cdd:TIGR02169 172 KEKALEELEEVEENIERLD----LIIDEKRQQLERLRREREKAERYQALLKEKREYE------------GYELLKEKEAL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 931 NKQLEEGMKEIlQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESR 1010
Cdd:TIGR02169 236 ERQKEAIERQL-ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKE 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1011 KEAINYSQQLAKANLKIDHLEKETSLLRQSEGSNVVFKgidlpdgiAPSSASIINSQNEYLIhLLQELENKEKKLKNLED 1090
Cdd:TIGR02169 315 RELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR--------DKLTEEYAELKEELED-LRAELEEVDKEFAETRD 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1091 SLEDYNRKFavirhqqsllyKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENS 1170
Cdd:TIGR02169 386 ELKDYREKL-----------EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1171 RKITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSELE 1250
Cdd:TIGR02169 455 WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVG 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1251 LANKQYNELTAKYR--DILQKDNMLVQRTsnLEHLECENISLK-----EQVESINKELEITKEK--------LHTIEQAW 1315
Cdd:TIGR02169 535 ERYATAIEVAAGNRlnNVVVEDDAVAKEA--IELLKRRKAGRAtflplNKMRDERRDLSILSEDgvigfavdLVEFDPKY 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1316 EQETK--LGNE---SSMDKAKKSITNSDIVSISKKI---------------------TMLEMKELNERQRAEHCQKMYEH 1369
Cdd:TIGR02169 613 EPAFKyvFGDTlvvEDIEAARRLMGKYRMVTLEGELfeksgamtggsraprggilfsRSEPAELQRLRERLEGLKRELSS 692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1370 LRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELEKNEmelkVEVSKLREISDIA 1449
Cdd:TIGR02169 693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN----VKSELKELEARIE 768
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1450 RRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEkslIAKLHQHNVslqlseatalGKLESITSKLQKMEAYNLRLEQKL 1529
Cdd:TIGR02169 769 ELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK---LEEEVSRIE----------ARLREIEQKLNRLTLEKEYLEKEI 835
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1530 DEKEQalyyARLEGRNRAKHLRQTIQSLRRQFsgALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEME 1609
Cdd:TIGR02169 836 QELQE----QRIDLKEQIKSIEKEIENLNGKK--EELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1610 LKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQEL--------KLNRELVKDKEEIKYLNNI----ISEYERTISSLE 1677
Cdd:TIGR02169 910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsleDVQAELQRVEEEIRALEPVnmlaIQEYEEVLKRLD 989
|
890
....*....|...
gi 767975378 1678 EEIVQQNKFHEER 1690
Cdd:TIGR02169 990 ELKEKRAKLEEER 1002
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
880-1486 |
3.13e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.74 E-value: 3.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 880 RNADIELEHHRSQAEQNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEiLQAIKEMQKDPDVKGGET 959
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE-LEELKEEIEELEKELESL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 960 SLIIPSLERLVNAIESKNAEgifdaslhLKAQVDQLTGRNEELrQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQ 1039
Cdd:PRK03918 251 EGSKRKLEEKIRELEERIEE--------LKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1040 SegSNVVFKGIdlpdgiapssaSIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKET 1119
Cdd:PRK03918 322 E--INGIEERI-----------KELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1120 WKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAE---NSRKITvlQVNEKSLIRQYTTLVELERQ 1196
Cdd:PRK03918 389 LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvCGRELT--EEHRKELLEEYTAELKRIEK 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1197 LRKENEKQKNELLSMEAEVCEKIGC---LQRFKEMAIFKIAALQKVvdNSVSLSELELANKQYNELTAKyrdilqkdnml 1273
Cdd:PRK03918 467 ELKEIEEKERKLRKELRELEKVLKKeseLIKLKELAEQLKELEEKL--KKYNLEELEKKAEEYEKLKEK----------- 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1274 vqrtsnLEHLECENISLKEQVESIN---KELEITKEKLHTIEQaweqetklgNESSMDKAKKSITNSDIVSISKKITMLE 1350
Cdd:PRK03918 534 ------LIKLKGEIKSLKKELEKLEelkKKLAELEKKLDELEE---------ELAELLKELEELGFESVEELEERLKELE 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1351 --MKELNERQRAEHcqkmyeHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLrDELADSVSKAVSDADRQRILEL 1428
Cdd:PRK03918 599 pfYNEYLELKDAEK------ELEREEKELKKLEEELDKAFEELAETEKRLEELRKEL-EELEKKYSEEEYEELREEYLEL 671
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767975378 1429 EKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDK-------------EVESLRMQLLDYQAQSDEKSL 1486
Cdd:PRK03918 672 SRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKakkeleklekaleRVEELREKVKKYKALLKERAL 742
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
115-567 |
3.26e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.74 E-value: 3.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 115 NEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLK---------KKNEQLCQDIIDYQK 185
Cdd:PRK03918 207 REINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIReleerieelKKEIEELEEKVKELK 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 186 QIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMR------KNLEESVQEMEKMTDEYNR 259
Cdd:PRK03918 287 ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEelkkklKELEKRLEELEERHELYEE 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 260 MKAIVHQTDNV---------------IDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAK--------------- 309
Cdd:PRK03918 367 AKAKKEELERLkkrltgltpeklekeLEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELkkakgkcpvcgrelt 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 310 -------VEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQErdsQIKMLTEQVEQYTKE-MEKN 381
Cdd:PRK03918 447 eehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAE---QLKELEEKLKKYNLEeLEKK 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 382 TCIIEDLKNELQRNKGastlsqqthmKIQSTLDILKEKtKEAERTAELAEADAREKDKELVEALKRL--------KDYES 453
Cdd:PRK03918 524 AEEYEKLKEKLIKLKG----------EIKSLKKELEKL-EELKKKLAELEKKLDELEEELAELLKELeelgfesvEELEE 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 454 GVYGLEDA---VVEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGlEPKTMIDLTEFRNSKHlKQQQ 530
Cdd:PRK03918 593 RLKELEPFyneYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE-ELEKKYSEEEYEELRE-EYLE 670
|
490 500 510
....*....|....*....|....*....|....*..
gi 767975378 531 YRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRS 567
Cdd:PRK03918 671 LSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
2069-2259 |
3.67e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.51 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2069 RHTRELKTQVEDLNENLLKLKEALKtskNRENSLtdnlndlnneLQKKQKAYNKILRE-KEEIDQENDELKRQIKRLTSG 2147
Cdd:PRK00409 537 EEAEALLKEAEKLKEELEEKKEKLQ---EEEDKL----------LEEAEKEAQQAIKEaKKEADEIIKELRQLQKGGYAS 603
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2148 LQGKPLTDNKQSLIEELQRKVKKL----ENQLEGKV-EEVDLKPMkekNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGE 2222
Cdd:PRK00409 604 VKAHELIEARKRLNKANEKKEKKKkkqkEKQEELKVgDEVKYLSL---GQKGEVLSIPDDKEAIVQAGIMKMKVPLSDLE 680
|
170 180 190
....*....|....*....|....*....|....*..
gi 767975378 2223 VFTLTKqlntlKDLFAKADKEKLtlqrKLKTTGMTVD 2259
Cdd:PRK00409 681 KIQKPK-----KKKKKKPKTVKP----KPRTVSLELD 708
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
1733-2182 |
4.07e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 42.73 E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1733 SLPLPNQLEIALRKIKEN-----IRIILETRATCKSLEEKlkekesalRLAEQNILSRDKVINELrlrlpataerEKLIA 1807
Cdd:PRK10929 21 TAPDEKQITQELEQAKAAktpaqAEIVEALQSALNWLEER--------KGSLERAKQYQQVIDNF----------PKLSA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1808 ELgRKEMEPKSHHTLKI-AHQTIANmqarLNQkeEVLKKYQRLLEKAREEQreivkkHEEDlhilhhRLELQADsSLNKF 1886
Cdd:PRK10929 83 EL-RQQLNNERDEPRSVpPNMSTDA----LEQ--EILQVSSQLLEKSRQAQ------QEQD------RAREISD-SLSQL 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1887 KQTAWDLMKQsptpvptnkhfirLAEMEQTVAEQDDSLSSLlvklkKVSQDLERQREITELKVKEFENIKLQLQENHEDE 1966
Cdd:PRK10929 143 PQQQTEARRQ-------------LNEIERRLQTLGTPNTPL-----AQAQLTALQAESAALKALVDELELAQLSANNRQE 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1967 VKKVKAEVEDLKYllDQSQKESQCLKSEL--QAQKEANSRAPTTTM-----RNLVERLKSQLalkeKQQKALSRALLELR 2039
Cdd:PRK10929 205 LARLRSELAKKRS--QQLDAYLQALRNQLnsQRQREAERALESTELlaeqsGDLPKSIVAQF----KINRELSQALNQQA 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2040 AEMTA-AAEERiiSATSQKeahLNVQQIVDRhTRE--------------LKTQVEDLNE---------NLLKLK-EALKT 2094
Cdd:PRK10929 279 QRMDLiASQQR--QAASQT---LQVRQALNT-LREqsqwlgvsnalgeaLRAQVARLPEmpkpqqldtEMAQLRvQRLRY 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2095 SK--NRENSLTDNLNDLNNELQKKQkayNKILrekeeidqeNDELKRQIKRLTSGLQGkpltdnKQSLIEELQrKVKKLE 2172
Cdd:PRK10929 353 EDllNKQPQLRQIRQADGQPLTAEQ---NRIL---------DAQLRTQRELLNSLLSG------GDTLILELT-KLKVAN 413
|
490
....*....|
gi 767975378 2173 NQLEGKVEEV 2182
Cdd:PRK10929 414 SQLEDALKEV 423
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
308-561 |
5.11e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.35 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 308 AKVEEWKLILSSKDDEIIEYQQMLHNLREKL--KNAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCII 385
Cdd:TIGR02168 691 EKIAELEKALAELRKELEELEEELEQLRKELeeLSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 386 EDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGvygLEDAVVEI 465
Cdd:TIGR02168 771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR---LEDLEEQI 847
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 466 KNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESL 545
Cdd:TIGR02168 848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
|
250
....*....|....*.
gi 767975378 546 EEERLDLKKKIRQMAQ 561
Cdd:TIGR02168 928 ELRLEGLEVRIDNLQE 943
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2018-2181 |
5.11e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2018 KSQLALKEKQQKALSRALLELRAEMTAAAEERIiSATSQKEAHLNVQQI---------VDRHTRELKTQVEDLNENLLKL 2088
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELD-ALQERREALQRLAEYswdeidvasAEREIAELEAELERLDASSDDL 687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 2089 KEalktsknrensLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKP---------------- 2152
Cdd:COG4913 688 AA-----------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdlarlelralleerfa 756
|
170 180 190
....*....|....*....|....*....|....*....
gi 767975378 2153 ----------LTDNKQSLIEELQRKVKKLENQLEGKVEE 2181
Cdd:COG4913 757 aalgdavereLRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| SHE3 |
pfam17078 |
SWI5-dependent HO expression protein 3; SWI5-dependent HO expression protein 3 (She3) is an ... |
162-297 |
6.94e-03 |
|
SWI5-dependent HO expression protein 3; SWI5-dependent HO expression protein 3 (She3) is an RNA-binding protein that binds specific mRNAs, including the mRNA of Ash1, which is invalid in cell-fate determination. She3 acts as an adapter protein that docks the myosin motor Myo4p onto an Ash1-She2p ribonucleoprotein complex. She3 seems to bind to Myo4p and Shep2p via different domains.
Pssm-ID: 293683 [Multi-domain] Cd Length: 228 Bit Score: 40.49 E-value: 6.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 162 LRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRK 241
Cdd:pfam17078 15 LTKTNLQLTVQSQNLLSKLEIAQQKESKFLENLASLKHENDNLSSMLNRKERRLKDLEDQLSELKNSYEELTESNKQLKK 94
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 767975378 242 NLEESVQEMEKMTDEYNRMKAivhQTDNVIDQLKKENDHYQLQVQELT---DLLKSKNE 297
Cdd:pfam17078 95 RLENSSASETTLEAELERLQI---QYDALVDSQNEYKDHYQQEINTLQeslEDLKLENE 150
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
111-258 |
7.53e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 41.23 E-value: 7.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 111 RFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDyqkqIDSQ 190
Cdd:PRK12705 28 RQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEK----LDNL 103
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767975378 191 KETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYN 258
Cdd:PRK12705 104 ENQLEEREKALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEEAD 171
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
30-554 |
7.58e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.54 E-value: 7.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 30 ISLSKVEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEvekagEEQAKFENQLKTKVMKLENELEMAQQSAGGRD 109
Cdd:TIGR04523 234 IEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKEL-----EQNNKKIKELEKQLNQLKSEISDLNNQKEQDW 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 110 TRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRREnkrLKKKNEQlcqdIIDYQKQIDS 189
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRE---LEEKQNE----IEKLKKENQS 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 190 QKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDN 269
Cdd:TIGR04523 382 YKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDN 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 270 VIDQLKKENDHYQLQVQELTDLLKSKNEEddpimvavnakveewkliLSSKDDEIIEYQQMLHNLREKLK--NAQLDADK 347
Cdd:TIGR04523 462 TRESLETQLKVLSRSINKIKQNLEQKQKE------------------LKSKEKELKKLNEEKKELEEKVKdlTKKISSLK 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 348 SNVMALQQGIQERDSQIKMLTEQVEqyTKEMEKNTCIIEDLKNELQRN----KGASTLSQQTHMKIQSTLDILKEKTKEA 423
Cdd:TIGR04523 524 EKIEKLESEKKEKESKISDLEDELN--KDDFELKKENLEKEIDEKNKEieelKQTQKSLKKKQEEKQELIDQKEKEKKDL 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 424 ERTAELAEADAREKDKELVEALKRLKDYESgvygledavvEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEAL 503
Cdd:TIGR04523 602 IKEIEEKEKKISSLEKELEKAKKENEKLSS----------IIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKES 671
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 767975378 504 RERVGlepkTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKK 554
Cdd:TIGR04523 672 KTKID----DIIELMKDWLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEK 718
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
1383-1479 |
7.89e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 41.10 E-value: 7.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 1383 ELETKFAELT-KINLDAQKVEQmLRDELAD-SVSKAVSDADRQRIL-----------ELEKNEMELKVEVSKLREISDIA 1449
Cdd:PRK09039 57 RLNSQIAELAdLLSLERQGNQD-LQDSVANlRASLSAAEAERSRLQallaelagagaAAEGRAGELAQELDSEKQVSARA 135
|
90 100 110
....*....|....*....|....*....|
gi 767975378 1450 RRQVEILNAQqqsrdkeVESLRMQLLDYQA 1479
Cdd:PRK09039 136 LAQVELLNQQ-------IAALRRQLAALEA 158
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
408-556 |
8.21e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 8.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975378 408 KIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYEsgvygleDAVVEIKNCKnQIKIRDREIEILTKEIN 487
Cdd:COG1579 35 ELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYE-------EQLGNVRNNK-EYEALQKEIESLKRRIS 106
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767975378 488 KLELKISDFLDENEALRERVGlepKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKI 556
Cdd:COG1579 107 DLEDEILELMERIEELEEELA---ELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172
|
|
| |
