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Conserved domains on  [gi|805752155|ref|XP_012140561|]
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PREDICTED: pyruvate kinase-like isoform X1 [Megachile rotundata]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pyruvate_Kinase cd00288
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ...
 287-774 0e+00

Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.


:

Pssm-ID: 238178 [Multi-domain]  Cd Length: 480  Bit Score: 739.90  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 287 RLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLSarnglnVPVAIALDTKGPEIRTG 366
Cdd:cd00288    2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTG------GPVAIALDTKGPEIRTG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 367 LLEGGgsAEVELQKGQTFKLSTDKAhAEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEV-ITTTIENGG 445
Cdd:cd00288   76 LFKGG--KDISLKAGDKFLVTTDPA-AKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 446 MLGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLD 525
Cdd:cd00288  153 VLGSRKGVNLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFD 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 526 EIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVML 605
Cdd:cd00288  233 EILEASDGIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVML 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 606 SGETAKGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLI 685
Cdd:cd00288  313 SGETAKGKYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLV 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 686 AKYRPRCPIIAVTRFHQVARQAHLHRGILPLYYEDAPlADWVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTGWRQGSGF 765
Cdd:cd00288  393 SKYRPNAPIIAVTRNEQTARQLHLYRGVYPVLFEEPK-PGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGSGS 471


                 ....*....
gi 805752155 766 TNTLRVVTV 774
Cdd:cd00288  472 TNTMRILTV 480
Mito_carr pfam00153
Mitochondrial carrier protein;
14-90 3.25e-17

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 77.31  E-value: 3.25e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155   14 GGLSSAGAACVTHPLDLLKVHLQTQQEGKLS----VVRLTTSIVKNQGILALYNGLSASLLRQLTYSTTRFGAYEVGKQT 89
Cdd:pfam00153  12 GGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSkgrgILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTYETLKRL 91


                  .
gi 805752155   90 F 90
Cdd:pfam00153  92 L 92
Mito_carr pfam00153
Mitochondrial carrier protein;
99-193 5.79e-16

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 73.84  E-value: 5.79e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155   99 FYQKLLLAGFSGAVGGVLGTPGDVINVRMQNDIKLAPELRRNykhALDGIVCIVQQEGFSKLFSGCTTATLRAALMTIGQ 178
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRG---ILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIY 81

                          90
                  ....*....|....*
gi 805752155  179 LSFYDQIKITMIESG 193
Cdd:pfam00153  82 FGTYETLKRLLLKKL 96
Mito_carr super family cl37969
Mitochondrial carrier protein;
195-255 5.10e-08

Mitochondrial carrier protein;


The actual alignment was detected with superfamily member pfam00153:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 51.12  E-value: 5.10e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 805752155  195 FEDNPVTHVLSSVCAGAVATTLTQPLDVLKTRAMNA---KPGEFKSLMDLFLYTAKL-GPLAFFK 255
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQggsGKSKGRGILDCFKKIYKEeGIRGLYK 65
 
Name Accession Description Interval E-value
Pyruvate_Kinase cd00288
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ...
 287-774 0e+00

Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.


Pssm-ID: 238178 [Multi-domain]  Cd Length: 480  Bit Score: 739.90  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 287 RLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLSarnglnVPVAIALDTKGPEIRTG 366
Cdd:cd00288    2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTG------GPVAIALDTKGPEIRTG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 367 LLEGGgsAEVELQKGQTFKLSTDKAhAEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEV-ITTTIENGG 445
Cdd:cd00288   76 LFKGG--KDISLKAGDKFLVTTDPA-AKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 446 MLGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLD 525
Cdd:cd00288  153 VLGSRKGVNLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFD 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 526 EIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVML 605
Cdd:cd00288  233 EILEASDGIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVML 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 606 SGETAKGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLI 685
Cdd:cd00288  313 SGETAKGKYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLV 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 686 AKYRPRCPIIAVTRFHQVARQAHLHRGILPLYYEDAPlADWVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTGWRQGSGF 765
Cdd:cd00288  393 SKYRPNAPIIAVTRNEQTARQLHLYRGVYPVLFEEPK-PGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGSGS 471


                 ....*....
gi 805752155 766 TNTLRVVTV 774
Cdd:cd00288  472 TNTMRILTV 480
pyruv_kin TIGR01064
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ...
 287-771 0e+00

pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 273424 [Multi-domain]  Cd Length: 472  Bit Score: 663.21  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  287 RLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLsarnglNVPVAIALDTKGPEIRTG 366
Cdd:TIGR01064   1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKL------GRPVAILLDTKGPEIRTG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  367 LLEGGgsaEVELQKGQTFKLSTDKAhAEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGM 446
Cdd:TIGR01064  75 EIKGG---EVKLKKGDKVIITTDDI-KGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGT 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  447 LGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKG-KNIKIISKIENQQGMTNLD 525
Cdd:TIGR01064 151 LKSKKGVNLPGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNID 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  526 EIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVML 605
Cdd:TIGR01064 231 EIAEASDGIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVML 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  606 SGETAKGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLI 685
Cdd:TIGR01064 311 SGETAKGKYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLL 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  686 AKYRPRCPIIAVTRFHQVARQAHLHRGILPLYYEdaplaDWVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTG-WRQGSG 764
Cdd:TIGR01064 391 SKYRPNAPIIAVTPNERVARQLALYWGVFPFLVD-----EEPSDTDARVNKALELLKEKGIVKKGDLVVVIQGgPIGGEG 465


                  ....*..
gi 805752155  765 FTNTLRV 771
Cdd:TIGR01064 466 GTNTIRV 472
PykF COG0469
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ...
 291-774 0e+00

Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440237 [Multi-domain]  Cd Length: 471  Bit Score: 654.03  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 291 IICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAqknlSARngLNVPVAIALDTKGPEIRTGLLEG 370
Cdd:COG0469    7 IVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREA----AKE--LGRPVAILLDLQGPKIRTGKFKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 371 GGsaeVELQKGQTFKLSTDKahaEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGMLGSR 450
Cdd:COG0469   81 GP---VELKKGDTFTLTTDD---VEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 451 KGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLDEIIEA 530
Cdd:COG0469  155 KGVNLPGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEA 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 531 SDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGETA 610
Cdd:COG0469  235 SDGIMVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETA 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 611 KGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKclASAIIVITTTGRSAHLIAKYRP 690
Cdd:COG0469  315 VGKYPVEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLG--AKAIVAFTESGSTARRISRYRP 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 691 RCPIIAVTRFHQVARQAHLHRGILPLYYEDapladwVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTGWRQG-SGFTNTL 769
Cdd:COG0469  393 KVPILALTPNERTARRLALVWGVYPVLVDD------VESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGvPGTTNTL 466


                 ....*
gi 805752155 770 RVVTV 774
Cdd:COG0469  467 KVHRV 471
PK pfam00224
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ...
 287-639 0e+00

Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.


Pssm-ID: 395168 [Multi-domain]  Cd Length: 348  Bit Score: 565.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  287 RLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLSARnglnvpVAIALDTKGPEIRTG 366
Cdd:pfam00224   2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGT------VAIALDTKGPEIRTG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  367 LLEGGgSAEVELQKGQTFKLSTDKAHAEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPE-VITTTIENGG 445
Cdd:pfam00224  76 NTKDG-KKDIELKAGDEMIVSTDAKYKGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGG 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  446 MLGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLD 525
Cdd:pfam00224 155 VIGSRKGVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFD 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  526 EIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVML 605
Cdd:pfam00224 235 EILEATDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVML 314

                         330       340       350
                  ....*....|....*....|....*....|....
gi 805752155  606 SGETAKGEYPLECVRTMANICKEAEAAIWQIQIF 639
Cdd:pfam00224 315 SGETAKGNYPVEAVRMMHEICLEAEKALPHRNLF 348
PRK05826 PRK05826
pyruvate kinase; Provisional
 291-758 0e+00

pyruvate kinase; Provisional


Pssm-ID: 235619 [Multi-domain]  Cd Length: 465  Bit Score: 552.45  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 291 IICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAqknlSARngLNVPVAIALDTKGPEIRTGLLEG 370
Cdd:PRK05826   8 IVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREI----AAK--LGRPVAILLDLKGPKIRVGKFKE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 371 GgsaEVELQKGQTFKLSTDKAhaEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGMLGSR 450
Cdd:PRK05826  82 G---KITLKTGDKFTLDTDQK--EEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 451 KGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKG-KNIKIISKIENQQGMTNLDEIIE 529
Cdd:PRK05826 157 KGINIPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGcPHAKIIAKIERAEAVDNIDEIIE 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 530 ASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGET 609
Cdd:PRK05826 237 ASDGIMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGET 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 610 AKGEYPLECVRTMANICKEAEaAIWQIQIFHDLANKALpPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLIAKYR 689
Cdd:PRK05826 317 AAGKYPVEAVEAMARICKGAE-KEFSINLSKHRLDRQF-DRIDEAIAMSAMYAANHLKGVKAIVALTESGRTARLISRFR 394

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 805752155 690 PRCPIIAVTRFHQVARQAHLHRGILPLYYEDApladwvKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTG 758
Cdd:PRK05826 395 PGAPIFAVTRDEKTQRRLALYRGVYPVLFDSA------ADTDDAAEEALRLLLEKGLVESGDLVVVTSG 457
Mito_carr pfam00153
Mitochondrial carrier protein;
14-90 3.25e-17

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 77.31  E-value: 3.25e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155   14 GGLSSAGAACVTHPLDLLKVHLQTQQEGKLS----VVRLTTSIVKNQGILALYNGLSASLLRQLTYSTTRFGAYEVGKQT 89
Cdd:pfam00153  12 GGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSkgrgILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTYETLKRL 91


                  .
gi 805752155   90 F 90
Cdd:pfam00153  92 L 92
Mito_carr pfam00153
Mitochondrial carrier protein;
99-193 5.79e-16

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 73.84  E-value: 5.79e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155   99 FYQKLLLAGFSGAVGGVLGTPGDVINVRMQNDIKLAPELRRNykhALDGIVCIVQQEGFSKLFSGCTTATLRAALMTIGQ 178
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRG---ILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIY 81

                          90
                  ....*....|....*
gi 805752155  179 LSFYDQIKITMIESG 193
Cdd:pfam00153  82 FGTYETLKRLLLKKL 96
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 14-186 1.84e-09

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 59.78  E-value: 1.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  14 GGLSSAGAACVTHPLDLLKVHLQT------QQEGKlSVVRLTTSIVKNQGILALYNGLSASLLRQLTYSTTRFGAYEVGK 87
Cdd:PTZ00169 120 GGLAGASSLLIVYPLDFARTRLASdigkggDREFT-GLFDCLMKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAK 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  88 QTFEKPGHSLLFYQKLLLAGFSGAVGGVLGTPGDVINVR--MQNDIKLAPELRrnYKHALDGIVCIVQQEGFSKLFSGCT 165
Cdd:PTZ00169 199 ALLFGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRmmMMSGRKAKSEIQ--YTGTLDCWKKILKNEGLGGFFKGAW 276

                        170       180
                 ....*....|....*....|....
gi 805752155 166 TATLR---AALMtigqLSFYDQIK 186
Cdd:PTZ00169 277 ANVLRgagGALV----LVFYDELQ 296
Mito_carr pfam00153
Mitochondrial carrier protein;
195-255 5.10e-08

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 51.12  E-value: 5.10e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 805752155  195 FEDNPVTHVLSSVCAGAVATTLTQPLDVLKTRAMNA---KPGEFKSLMDLFLYTAKL-GPLAFFK 255
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQggsGKSKGRGILDCFKKIYKEeGIRGLYK 65
 
Name Accession Description Interval E-value
Pyruvate_Kinase cd00288
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ...
 287-774 0e+00

Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.


Pssm-ID: 238178 [Multi-domain]  Cd Length: 480  Bit Score: 739.90  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 287 RLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLSarnglnVPVAIALDTKGPEIRTG 366
Cdd:cd00288    2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTG------GPVAIALDTKGPEIRTG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 367 LLEGGgsAEVELQKGQTFKLSTDKAhAEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEV-ITTTIENGG 445
Cdd:cd00288   76 LFKGG--KDISLKAGDKFLVTTDPA-AKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 446 MLGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLD 525
Cdd:cd00288  153 VLGSRKGVNLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFD 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 526 EIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVML 605
Cdd:cd00288  233 EILEASDGIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVML 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 606 SGETAKGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLI 685
Cdd:cd00288  313 SGETAKGKYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLV 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 686 AKYRPRCPIIAVTRFHQVARQAHLHRGILPLYYEDAPlADWVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTGWRQGSGF 765
Cdd:cd00288  393 SKYRPNAPIIAVTRNEQTARQLHLYRGVYPVLFEEPK-PGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGSGS 471


                 ....*....
gi 805752155 766 TNTLRVVTV 774
Cdd:cd00288  472 TNTMRILTV 480
pyruv_kin TIGR01064
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ...
 287-771 0e+00

pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 273424 [Multi-domain]  Cd Length: 472  Bit Score: 663.21  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  287 RLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLsarnglNVPVAIALDTKGPEIRTG 366
Cdd:TIGR01064   1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKL------GRPVAILLDTKGPEIRTG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  367 LLEGGgsaEVELQKGQTFKLSTDKAhAEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGM 446
Cdd:TIGR01064  75 EIKGG---EVKLKKGDKVIITTDDI-KGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGT 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  447 LGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKG-KNIKIISKIENQQGMTNLD 525
Cdd:TIGR01064 151 LKSKKGVNLPGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNID 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  526 EIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVML 605
Cdd:TIGR01064 231 EIAEASDGIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVML 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  606 SGETAKGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLI 685
Cdd:TIGR01064 311 SGETAKGKYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLL 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  686 AKYRPRCPIIAVTRFHQVARQAHLHRGILPLYYEdaplaDWVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTG-WRQGSG 764
Cdd:TIGR01064 391 SKYRPNAPIIAVTPNERVARQLALYWGVFPFLVD-----EEPSDTDARVNKALELLKEKGIVKKGDLVVVIQGgPIGGEG 465


                  ....*..
gi 805752155  765 FTNTLRV 771
Cdd:TIGR01064 466 GTNTIRV 472
PykF COG0469
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ...
 291-774 0e+00

Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440237 [Multi-domain]  Cd Length: 471  Bit Score: 654.03  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 291 IICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAqknlSARngLNVPVAIALDTKGPEIRTGLLEG 370
Cdd:COG0469    7 IVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREA----AKE--LGRPVAILLDLQGPKIRTGKFKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 371 GGsaeVELQKGQTFKLSTDKahaEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGMLGSR 450
Cdd:COG0469   81 GP---VELKKGDTFTLTTDD---VEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 451 KGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLDEIIEA 530
Cdd:COG0469  155 KGVNLPGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEA 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 531 SDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGETA 610
Cdd:COG0469  235 SDGIMVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETA 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 611 KGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKclASAIIVITTTGRSAHLIAKYRP 690
Cdd:COG0469  315 VGKYPVEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLG--AKAIVAFTESGSTARRISRYRP 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 691 RCPIIAVTRFHQVARQAHLHRGILPLYYEDapladwVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTGWRQG-SGFTNTL 769
Cdd:COG0469  393 KVPILALTPNERTARRLALVWGVYPVLVDD------VESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGvPGTTNTL 466


                 ....*
gi 805752155 770 RVVTV 774
Cdd:COG0469  467 KVHRV 471
PK pfam00224
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ...
 287-639 0e+00

Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.


Pssm-ID: 395168 [Multi-domain]  Cd Length: 348  Bit Score: 565.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  287 RLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLSARnglnvpVAIALDTKGPEIRTG 366
Cdd:pfam00224   2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGT------VAIALDTKGPEIRTG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  367 LLEGGgSAEVELQKGQTFKLSTDKAHAEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPE-VITTTIENGG 445
Cdd:pfam00224  76 NTKDG-KKDIELKAGDEMIVSTDAKYKGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGG 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  446 MLGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLD 525
Cdd:pfam00224 155 VIGSRKGVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFD 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  526 EIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVML 605
Cdd:pfam00224 235 EILEATDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVML 314

                         330       340       350
                  ....*....|....*....|....*....|....
gi 805752155  606 SGETAKGEYPLECVRTMANICKEAEAAIWQIQIF 639
Cdd:pfam00224 315 SGETAKGNYPVEAVRMMHEICLEAEKALPHRNLF 348
PRK05826 PRK05826
pyruvate kinase; Provisional
 291-758 0e+00

pyruvate kinase; Provisional


Pssm-ID: 235619 [Multi-domain]  Cd Length: 465  Bit Score: 552.45  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 291 IICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAqknlSARngLNVPVAIALDTKGPEIRTGLLEG 370
Cdd:PRK05826   8 IVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREI----AAK--LGRPVAILLDLKGPKIRVGKFKE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 371 GgsaEVELQKGQTFKLSTDKAhaEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGMLGSR 450
Cdd:PRK05826  82 G---KITLKTGDKFTLDTDQK--EEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 451 KGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKG-KNIKIISKIENQQGMTNLDEIIE 529
Cdd:PRK05826 157 KGINIPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGcPHAKIIAKIERAEAVDNIDEIIE 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 530 ASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGET 609
Cdd:PRK05826 237 ASDGIMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGET 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 610 AKGEYPLECVRTMANICKEAEaAIWQIQIFHDLANKALpPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLIAKYR 689
Cdd:PRK05826 317 AAGKYPVEAVEAMARICKGAE-KEFSINLSKHRLDRQF-DRIDEAIAMSAMYAANHLKGVKAIVALTESGRTARLISRFR 394

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 805752155 690 PRCPIIAVTRFHQVARQAHLHRGILPLYYEDApladwvKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTG 758
Cdd:PRK05826 395 PGAPIFAVTRDEKTQRRLALYRGVYPVLFDSA------ADTDDAAEEALRLLLEKGLVESGDLVVVTSG 457
PLN02461 PLN02461
Probable pyruvate kinase
 291-756 0e+00

Probable pyruvate kinase


Pssm-ID: 215255 [Multi-domain]  Cd Length: 511  Bit Score: 545.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 291 IICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLsarnglNVPVAIALDTKGPEIRTGLLEG 370
Cdd:PLN02461  25 IVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANT------GILCAVMLDTKGPEIRTGFLKD 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 371 GGSaeVELQKGQTFKLSTDKAHaeKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPE--VITTTIENGGMLG 448
Cdd:PLN02461  99 GKP--VQLKQGQEITITTDYSI--KGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVEagTVRCRCENSAMLG 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 449 SRKGVNLPGVPVDLPAVSEKDKSD-LQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLDEI 527
Cdd:PLN02461 175 ERKNVNLPGVVVDLPTLTEKDKEDiLQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLDNFDDI 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 528 IEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSG 607
Cdd:PLN02461 255 LAESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSG 334

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 608 ETAKGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLIAK 687
Cdd:PLN02461 335 ETAAGAYPELAVKTMARICREAEASLDYGALFKEIMRSAPLPMSPLESLASSAVRTANKVKASLIVVLTRGGTTARLVAK 414

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 688 YRPRCPIIAV------TRFHQ-------VARQAHLHRGILPLYYEDAPLADWVKDVDVRVQTGLNFGKSRGFVKTGDSVV 754
Cdd:PLN02461 415 YRPAVPILSVvvpeitTDSFDwscsdeaPARHSLIYRGLIPVLAEGSAKATDSESTEEILEAAIEHAKKKGLCKPGDSVV 494


                 ..
gi 805752155 755 VV 756
Cdd:PLN02461 495 AL 496
PRK09206 PRK09206
pyruvate kinase PykF;
291-771 2.87e-178

pyruvate kinase PykF;


Pssm-ID: 181699 [Multi-domain]  Cd Length: 470  Bit Score: 519.23  E-value: 2.87e-178
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 291 IICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLsarnglNVPVAIALDTKGPEIRTGLLEG 370
Cdd:PRK09206   6 IVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKT------GKKAAILLDTKGPEIRTMKLEG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 371 GgsAEVELQKGQTFKLSTDKAhaEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGMLGSR 450
Cdd:PRK09206  80 G--NDVSLKAGQTFTFTTDKS--VVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGEN 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 451 KGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGE-KGKNIKIISKIENQQGMTNLDEIIE 529
Cdd:PRK09206 156 KGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAhGGENIQIISKIENQEGLNNFDEILE 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 530 ASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGET 609
Cdd:PRK09206 236 ASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGES 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 610 AKGEYPLECVRTMANICKEAEAAIwQIQIFHDLANKALppvDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLIAKYR 689
Cdd:PRK09206 316 AKGKYPLEAVSIMATICERTDRVM-NSRLESNNDNRKL---RITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYF 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 690 PRCPIIAVTRFHQVARQAHLHRGILPLyyedapLADWVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTGWRQGSGFTNTL 769
Cdd:PRK09206 392 PDATILALTTNEKTARQLVLSKGVVPQ------LVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSGALVPSGTTNTA 465


                 ..
gi 805752155 770 RV 771
Cdd:PRK09206 466 SV 467
PTZ00300 PTZ00300
pyruvate kinase; Provisional
 313-774 9.64e-177

pyruvate kinase; Provisional


Pssm-ID: 140321 [Multi-domain]  Cd Length: 454  Bit Score: 514.60  E-value: 9.64e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 313 MNIARLNFSHGSHEYHAETISNVRQAQKNLsarnGLNVpvAIALDTKGPEIRTGLLEGGGSAeveLQKGQTFKLSTDKAH 392
Cdd:PTZ00300   1 MSVARMNFSHGSHEYHQTTINNVRQAAAEL----GVNI--AIALDTKGPEIRTGLFVGGEAV---MERGATCYVTTDPAF 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 393 AEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPE-VITTTIENGGMLGSRKGVNLPGVPVDLPAVSEKDKS 471
Cdd:PTZ00300  72 ADKGTKDKFYIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEqTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCA 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 472 DLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLDEIIEASDGIMVARGDLGIEIPPEKVF 551
Cdd:PTZ00300 152 DLQFGVEQGVDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVV 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 552 LAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGETAKGEYPLECVRTMANICKEAEA 631
Cdd:PTZ00300 232 VAQKILISKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQS 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 632 AIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLIAKYRPRCPIIAVTRFHQVARQAHLHR 711
Cdd:PTZ00300 312 AVNEYVFFNSIKKLQPIPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQ 391

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 805752155 712 GILPLYYeDAPLADWVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTGWRQGSGFTNTLRVVTV 774
Cdd:PTZ00300 392 GVESVFF-DAERLGHDEGKEQRVAMGVGFAKSKGYVQSGDLMVVVHADHKVKGYANQTRIILV 453
PTZ00066 PTZ00066
pyruvate kinase; Provisional
 291-774 2.20e-172

pyruvate kinase; Provisional


Pssm-ID: 173361 [Multi-domain]  Cd Length: 513  Bit Score: 505.84  E-value: 2.20e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 291 IICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLSarnglNVPVAIALDTKGPEIRTGLLEG 370
Cdd:PTZ00066  42 IVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKARP-----NANLGILLDTKGPEIRTGFLKN 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 371 GgsAEVELQKGQTFKLSTDkaHAEKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGMLGSR 450
Cdd:PTZ00066 117 H--KPITLKEGQTLKITTD--YTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGER 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 451 KGVNLPGVPVDLPAVSEKDKSD-LQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNIKIISKIENQQGMTNLDEIIE 529
Cdd:PTZ00066 193 KNMNLPGVKVELPVIGEKDKNDiLNFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIPKIENIEGLINFDEILA 272

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 530 ASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGET 609
Cdd:PTZ00066 273 ESDGIMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGET 352

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 610 AKGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLIAKYR 689
Cdd:PTZ00066 353 ANGKFPVEAVNIMAKICFEAETCIDYRVLYHAIHLAVPTPVSVQEAVARSAVETAEDINAKLIIALTETGNTARLISKYR 432

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 690 PRCPIIAVTRFHQVARQAHLHRGILplyyedAPLADWVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTGWRQG-SGFTNT 768
Cdd:PTZ00066 433 PSCTILALSASPSVVKSLSVARGVT------TYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEvAGSSNL 506


                 ....*.
gi 805752155 769 LRVVTV 774
Cdd:PTZ00066 507 MKVVKI 512
PRK06354 PRK06354
pyruvate kinase; Provisional
 281-774 9.13e-167

pyruvate kinase; Provisional


Pssm-ID: 235784 [Multi-domain]  Cd Length: 590  Bit Score: 494.06  E-value: 9.13e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 281 SRASFVRLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLsarnglNVPVAIALDTKG 360
Cdd:PRK06354   2 SLRDLMRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKL------GKTVGILQDLQG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 361 PEIRTGLLEGGGsaeVELQKGQTFKLSTDKAhaeKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEV--IT 438
Cdd:PRK06354  76 PKIRLGRFEDGP---IELKTGDEFILTSREV---LGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKADgeLH 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 439 TTIENGGMLGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEK-GKNIKIISKIEN 517
Cdd:PRK06354 150 CKVLVGGVLSNKKGVNFPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHnGKHIPIIAKIEK 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 518 QQGMTNLDEIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAIL 597
Cdd:PRK06354 230 QEAIDNIDAILELCDGLMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAIL 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 598 DGADCVMLSGETAKGEYPLECVRTMANICKEAEAAIWQIQIF-HDLANKALPPVDATHAVAVAAVEASvkclASAIIVIT 676
Cdd:PRK06354 310 DGTDAVMLSNETAAGDYPVEAVQTMATIAVRIEKDLPYRDILsKRPEFTTTITNAISQAVSHIALQLD----AAAIVTLT 385

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 677 TTGRSAHLIAKYRPRCPIIAVTRFHQVARQAHLHRGILPLYYEDAPLADWVkdvdvrVQTGLNFGKSRGFVKTGDSVVVV 756
Cdd:PRK06354 386 KSGATARNVSKYRPKTPILAVTPNESVARRLQLVWGVTPLLVLDAPSTDET------FDAAINVAQESGLLKQGDLVVIT 459

                        490
                 ....*....|....*....
gi 805752155 757 TGWRQG-SGFTNTLRVVTV 774
Cdd:PRK06354 460 AGTLVGeSGSTDLMKVHVV 478
PRK06247 PRK06247
pyruvate kinase; Provisional
 291-774 4.93e-143

pyruvate kinase; Provisional


Pssm-ID: 180487 [Multi-domain]  Cd Length: 476  Bit Score: 428.96  E-value: 4.93e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 291 IICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLsarnglNVPVAIALDTKGPEIRTGLLEG 370
Cdd:PRK06247   9 ILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDET------GRPIGILADLQGPKLRLGRFAD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 371 GgsaEVELQKGQTFKLSTDKAHaekGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGMLGSR 450
Cdd:PRK06247  83 G---KVQLANGQTFRLDVDDAP---GDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDR 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 451 KGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKgknIKIISKIENQQGMTNLDEIIEA 530
Cdd:PRK06247 157 KGVSLPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKIIGGR---VPVMAKIEKPQAIDRLEAIVEA 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 531 SDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGETA 610
Cdd:PRK06247 234 SDAIMVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETA 313

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 611 KGEYPLECVRTMANICKEAEAAiwqiQIFHDL--ANKALPPVDATHAVAVAAVEASVKCLASAIIVITTTGRSAHLIAKY 688
Cdd:PRK06247 314 SGKYPVEAVRTMARIIRQVERD----PTYPPLihAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARE 389

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 689 RPRCPIIAVTRFHQVARQAHLHRGIlplyyeDAPLADWVKDVDVRVQTGLNFGKSRGFVKTGDSVVVVTGWRQG-SGFTN 767
Cdd:PRK06247 390 RPPLPILALTPNPETARRLALTWGV------HCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGtPGSTN 463


                 ....*..
gi 805752155 768 TLRVVTV 774
Cdd:PRK06247 464 MLRIAYI 470
PLN02765 PLN02765
pyruvate kinase
 280-775 5.23e-117

pyruvate kinase


Pssm-ID: 215409 [Multi-domain]  Cd Length: 526  Bit Score: 363.61  E-value: 5.23e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 280 ESRASFV-RLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLsarnglNVPVAIALDT 358
Cdd:PLN02765  20 PSKPSFFpALTKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNT------KKLCAVMLDT 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 359 KGPEIrtGLLEGGGSAeVELQKGQTFKLSTDKAhaEKGNANLVYVDYDNISKVLKVGNRVFVDDGLIS--------LIVT 430
Cdd:PLN02765  94 VGPEL--QVINKTEKP-ISLKAGNTVTLTPDQS--KEASSEVLPINFPGLAKAVKPGDTIFVGQYLFTgsettsvwLEVD 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 431 AVSPEVITTTIENGGML-GSRKGVNLPGVPVDLPAVSEKDKSDL-QFGVEQEVDMIFASFIRNAAALTEIRSILGEKG-K 507
Cdd:PLN02765 169 EVKGDDVVCTVKNSATLaGSLFTLHVSQVRIDLPTLSEKDKEVIsTWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGlS 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 508 NIKIISKIENQQGMTNLDEIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVIcATQMLESMVKKPRATRA 587
Cdd:PLN02765 249 QTQIFAKIENVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAV-VTRVVDSMTDNLRPTRA 327

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 588 ETSDVANAILDGADCVMLSGETAKGEYPLECVRTMANICKEAEAAIWQIQIFHDLANKALPPVDATHAVAVAAVEASVKC 667
Cdd:PLN02765 328 EATDVANAVLDGADAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKKTVKYVGEPMSHLESIASSAVRAAIKV 407

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 668 LASAIIVITTTGRSAHLIAKYRPRCPIIAVT-----------RFH--QVARQAHLHRGILPLyyedapLADWVKDVDVRV 734
Cdd:PLN02765 408 KASVIIVFTSSGRAARLIAKYRPTMPVLSVViprlktnqlkwSFTgaFQARQCLIVRGLFPM------LADPRHSAESTS 481

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 805752155 735 QTG-------LNFGKSRGFVKTGDSVVVVtgwrQGSGFTNTLRVVTVD 775
Cdd:PLN02765 482 ATNesvlkvaLDHGKAAGVIKSHDRVVVC----QKVGDSSVVKIIELD 525
PLN02623 PLN02623
pyruvate kinase
 260-763 3.60e-109

pyruvate kinase


Pssm-ID: 215334 [Multi-domain]  Cd Length: 581  Bit Score: 344.99  E-value: 3.60e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 260 PNTQALYAQSQLDHMCALDIESRASFVRLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVrqaq 339
Cdd:PLN02623  83 EDNEEVLLEIQQLGETAVGMWSKPSVRRKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLV---- 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 340 KNLSARNGLNVpVAIALDTKGPEIRTGLLegggSAEVELQKGQTFKLSTDKAhaeKGNANLVYVDYDNISKVLKVGNRVF 419
Cdd:PLN02623 159 KEYNAQSKDNV-IAIMLDTKGPEVRSGDL----PQPIMLEEGQEFTFTIKRG---VSTEDCVSVNYDDFVNDVEVGDMLL 230

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 420 VDDGLISLIVTAVSPEVITTTIENGGMLGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIR 499
Cdd:PLN02623 231 VDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELK 310

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 500 SILGEKGKNIKIISKIENQQGMTNLDEIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMV 579
Cdd:PLN02623 311 DYLKSCNADIHVIVKIESADSIPNLHSIITASDGAMVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMI 390

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 580 KKPRATRAETSDVANAILDGADCVMLSGETAKGEYPLECVRTMANICKEAEAAiwqiqifhdLANKALPPVDATHAVAVA 659
Cdd:PLN02623 391 VHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPLKAVKVMHTVALRTEAT---------LPEGTTPPNLGQAFKNHM 461

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 660 A------VEASVKCLASAIIVITTTGRSAHLIAKYRPRCPIIAVTRFHQVARQAHLHRGILPLYYEdapladWVKDVDVR 733
Cdd:PLN02623 462 SemfafhATMMANTLGTSIIVFTRTGFMAILLSHYRPSGTIFAFTNEKRIQQRLALYQGVCPIYMQ------FSDDAEET 535

                        490       500       510
                 ....*....|....*....|....*....|....*
gi 805752155 734 VQTGLNFGKSRGFVKTGDSVVVVTG-----WRQGS 763
Cdd:PLN02623 536 FARALSLLLNKGMVKEGEEVALVQSgrqpiWRSES 570
PRK06739 PRK06739
pyruvate kinase; Validated
 292-630 4.21e-103

pyruvate kinase; Validated


Pssm-ID: 180676 [Multi-domain]  Cd Length: 352  Bit Score: 321.12  E-value: 4.21e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 292 ICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQaqknlsarngLNVPVAIALDTKGPEIRTGLLEGg 371
Cdd:PRK06739   6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKS----------LDDSIKILGDVQGPKIRLGEIKG- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 372 gsAEVELQKGQTFKLSTDKAhaeKGNANLVYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPEVITTTIENGGMLGSRK 451
Cdd:PRK06739  75 --EQITLQAGDSFILHTQPV---TGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHK 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 452 GVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKNI-KIISKIENQQGMTNLDEIIEA 530
Cdd:PRK06739 150 GVNLPGAIVRLPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSpNLIAKIETMEAIENFQDICKE 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 531 SDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGETA 610
Cdd:PRK06739 230 ADGIMIARGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESA 309

                        330       340
                 ....*....|....*....|
gi 805752155 611 KGEYPLECVRTMANICKEAE 630
Cdd:PRK06739 310 SGEHPIESVSTLRLVSEFAE 329
PLN02762 PLN02762
pyruvate kinase complex alpha subunit
 286-757 1.07e-90

pyruvate kinase complex alpha subunit


Pssm-ID: 215407 [Multi-domain]  Cd Length: 509  Bit Score: 293.96  E-value: 1.07e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 286 VRLSGIICTIGPASRSVETLEKMIETGMNIARLNFSHGSHEYHAETISNVRQaqknLSARNGLNVpvAIALDTKGPEIRT 365
Cdd:PLN02762  24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRR----LNEEKGFAV--AVMMDTEGSEIHM 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 366 GLLEGGGSAEVELQKGQTFKL-STDKAHAEKgnanLVYVDYDNISKVLKVGNRVFVDDGLISL-IVTAVSPEVITTTIEN 443
Cdd:PLN02762  98 GDLGGASSAKAEDGEEWTFTVrKFDGSRPEF----TIQVNYDGFAEDVKVGDELVVDGGMVRFeVIEKIGPDVKCKCTDP 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 444 GGMLGS------RKGVNLPGVPVDLPAVSEKDKSDLQFGVEQEVDMIFASFIRNAAALTEIRSILGEKGKN--IKIISKI 515
Cdd:PLN02762 174 GLLLPRanltfwRDGSLVRERNAMLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSRDsdIGVIAKI 253

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 516 ENQQGMTNLDEIIEASDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANA 595
Cdd:PLN02762 254 ESLDSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEA 333

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 596 ILDGADCVMLSGETAKGEYP---LECVRT----MANICKEA--EAAIWQIQIFHDLANKalppvdATHAVAVAAVEASVK 666
Cdd:PLN02762 334 VRQRADALMLSGESAMGLYPekaLSVLRSvslrMELWSREEkrHEALELPQLSSSLSDR------ISEEICNSAAKMANN 407

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 667 CLASAIIVITTTGRSAHLIAKYRPRCPIIAVTRFHQVARQAHLHRGILPLyyedapLADWVKDVDVRVQTGLNFGKSRGF 746
Cdd:PLN02762 408 LGVDAIFVYTKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPF------RLDFSDDMESNLNKTFSLLKARGM 481

                        490
                 ....*....|.
gi 805752155 747 VKTGDSVVVVT 757
Cdd:PLN02762 482 IKSGDLVIAVS 492
PRK08187 PRK08187
pyruvate kinase; Validated
 308-625 7.72e-50

pyruvate kinase; Validated


Pssm-ID: 236178  Cd Length: 493  Bit Score: 182.52  E-value: 7.72e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 308 MIETGMNIARLNFSHGSHEYHAETISNVRQAQKNLSARnglnvpVAIALDTKGPEIRTGLLeGGGSAEVELQKGQTFKLS 387
Cdd:PRK08187 155 LAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRR------CKILMDLAGPKIRTGAV-AGPLGKTRLYTGDRLALV 227

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 388 TDKAHAEKGNANL-VYVDYDNISKVLKVGNRVFVDDGLISLIVTAVSPE----VITTTIENGGMLGSRKGVNLPGVPVDL 462
Cdd:PRK08187 228 AQGPPRRIDEEHFqVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGgallEVTHARPKGLKLKPEKGLNFPDTALDL 307

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 463 PAVSEKDKSDLQFgVEQEVDMIFASFIRNAAALTEIRSILGEKGKN----IKIISKIENQQGMTNLDEIIEASDG----- 533
Cdd:PRK08187 308 PALTEKDRADLDF-VARHADLVGYSFVQSPGDVEALQAALAARRPDdwrkLGLVLKIETPRAVANLPELIVQAAGrqpfg 386

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 534 IMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAilDGADCVMLSgetaKGE 613
Cdd:PRK08187 387 VMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAMA--ARAECVMLN----KGP 460

                        330
                 ....*....|..
gi 805752155 614 YPLECVRTMANI 625
Cdd:PRK08187 461 YLVEAVTFLDDL 472
PRK14725 PRK14725
pyruvate kinase; Provisional
 305-625 3.47e-40

pyruvate kinase; Provisional


Pssm-ID: 237804  Cd Length: 608  Bit Score: 157.03  E-value: 3.47e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 305 LEKMIETGMNIARLNFSHGSHEYHAETISNVRQAqknlSARNGLnvPVAIALDTKGPEIRTGLLEGGG------------ 372
Cdd:PRK14725 158 VRRLLAAGMDIARINCAHDDPEAWRAMIANVRTA----EEELGR--RCRIAMDLAGPKLRTGPIAPGPrviklrptrdal 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 373 ---------------SAEVE-----------------LQKGQTFKLsTDKAHAEK--------GNANLVYVD---Y---- 405
Cdd:PRK14725 232 grvltparlwltaseSPPPSpppgpvglpvdpewlarLEPGDELRF-TDARGKKRkltvtevdDEGVLAEGSqtaYlang 310

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 406 ----------------------------------------------DNISKV----------LKVGNRVFVDDGLISLIV 429
Cdd:PRK14725 311 tllrlgrhdstrvgglppveqklrlkvgdrlvltrddapgdpaqgdAPPARIsctlpeafraARVGERVWFDDGKIGAVV 390

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 430 TAVSPEVITTTIENGGMLGSR----KGVNLPGVPVDLPAVSEKDKSDLQFgVEQEVDMIFASFIRNAAALTEIRSILGE- 504
Cdd:PRK14725 391 VKVEADEVELRITHARPGGSKlkagKGINLPDSHLPLPALTDKDLEDLAF-VAKHADIVALSFVRSPEDVRLLLDALEKl 469

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 505 KGKNIKIISKIENQQGMTNLDEII-EA----SDGIMVARGDLGIEIPPEKVFLAQKCMISRCNKVGKPVICATQMLESMV 579
Cdd:PRK14725 470 GADDLGVVLKIETRRAFENLPRILlEAmrhpRFGVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVLESLA 549

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*.
gi 805752155 580 KKPRATRAETSDVANAILdgADCVMLSgetaKGEYPLECVRTMANI 625
Cdd:PRK14725 550 KKGLPSRAEITDAAMALR--AECVMLN----KGPHIVEAVRVLDDI 589
PykA2 COG3848
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
560-775 1.98e-39

Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];


Pssm-ID: 443058  Cd Length: 321  Bit Score: 148.51  E-value: 1.98e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 560 RCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGETAKGEYPLECVRTMANICKEAEAAIwqiqif 639
Cdd:COG3848    1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDL------ 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 640 hdLANKALPPVDATHAVAVAAVEASVKC------LASAIIVITTTGRSAHLIAKYRPRCPIIAVTRFHQVARQAHLHRGI 713
Cdd:COG3848   75 --EYREQRVPRAKESSTTITDAISHAVAttaadlGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGV 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 805752155 714 LPLYYEDAPLADWVKDVDVRVQTGlnfgksRGFVKTGDSVVVVTGWRQG-SGFTNTLRVVTVD 775
Cdd:COG3848  153 YPLLVEESASTDEMFAVAVALALE------AGLVKDGDLVVITAGVPVGvSGTTNLLKVHVVG 209
PK_C pfam02887
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ...
 669-772 2.21e-34

Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.


Pssm-ID: 460738 [Multi-domain]  Cd Length: 114  Bit Score: 126.83  E-value: 2.21e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  669 ASAIIVITTTGRSAHLIAKYRPRCPIIAVTRFHQVARQAHLHRGILPLYYEDApladwvKDVDVRVQTGLNFGKSRGFVK 748
Cdd:pfam02887  16 AKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEA------ETTDEMLRRAVKVAKEAGLVK 89

                          90       100
                  ....*....|....*....|....*
gi 805752155  749 TGDSVVVVTGWRQG-SGFTNTLRVV 772
Cdd:pfam02887  90 KGDLVVITAGVPFGvSGTTNTLKVI 114
Mito_carr pfam00153
Mitochondrial carrier protein;
14-90 3.25e-17

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 77.31  E-value: 3.25e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155   14 GGLSSAGAACVTHPLDLLKVHLQTQQEGKLS----VVRLTTSIVKNQGILALYNGLSASLLRQLTYSTTRFGAYEVGKQT 89
Cdd:pfam00153  12 GGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSkgrgILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTYETLKRL 91


                  .
gi 805752155   90 F 90
Cdd:pfam00153  92 L 92
Mito_carr pfam00153
Mitochondrial carrier protein;
99-193 5.79e-16

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 73.84  E-value: 5.79e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155   99 FYQKLLLAGFSGAVGGVLGTPGDVINVRMQNDIKLAPELRRNykhALDGIVCIVQQEGFSKLFSGCTTATLRAALMTIGQ 178
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRG---ILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIY 81

                          90
                  ....*....|....*
gi 805752155  179 LSFYDQIKITMIESG 193
Cdd:pfam00153  82 FGTYETLKRLLLKKL 96
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 14-186 1.84e-09

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 59.78  E-value: 1.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  14 GGLSSAGAACVTHPLDLLKVHLQT------QQEGKlSVVRLTTSIVKNQGILALYNGLSASLLRQLTYSTTRFGAYEVGK 87
Cdd:PTZ00169 120 GGLAGASSLLIVYPLDFARTRLASdigkggDREFT-GLFDCLMKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAK 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  88 QTFEKPGHSLLFYQKLLLAGFSGAVGGVLGTPGDVINVR--MQNDIKLAPELRrnYKHALDGIVCIVQQEGFSKLFSGCT 165
Cdd:PTZ00169 199 ALLFGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRmmMMSGRKAKSEIQ--YTGTLDCWKKILKNEGLGGFFKGAW 276

                        170       180
                 ....*....|....*....|....
gi 805752155 166 TATLR---AALMtigqLSFYDQIK 186
Cdd:PTZ00169 277 ANVLRgagGALV----LVFYDELQ 296
Mito_carr pfam00153
Mitochondrial carrier protein;
195-255 5.10e-08

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 51.12  E-value: 5.10e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 805752155  195 FEDNPVTHVLSSVCAGAVATTLTQPLDVLKTRAMNA---KPGEFKSLMDLFLYTAKL-GPLAFFK 255
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQggsGKSKGRGILDCFKKIYKEeGIRGLYK 65
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 1-257 1.90e-06

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 50.54  E-value: 1.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155   1 MEDKTKKLARWYFGGLSSAGAACVTHPLDLLKVHLQTQ------QEGKL----SVVRLTTSIVKNQGILALYNGLSASLL 70
Cdd:PTZ00169   1 MDKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTQdsipeiKSGKVprysGIVNCFRRVSKEQGVLSLWRGNTANVI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  71 RQLTYSTTRFGAYEVGKQTFEKPGHSLLFYQ----KLLLAGFSGAVGGVLGTPGDVINVRMQNDIklAPELRRNYKHALD 146
Cdd:PTZ00169  81 RYFPTQAFNFAFKDYFKNMFPKYNQKTDFWKffgvNILSGGLAGASSLLIVYPLDFARTRLASDI--GKGGDREFTGLFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155 147 GIVCIVQQEGFSKLFSGCTTATLRAALMTIGQLSFYDQIKITMiesgyFEDNPVTHVLSSvcaGAVATTLT-------QP 219
Cdd:PTZ00169 159 CLMKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALL-----FGNDKNTNILYK---WAVAQTVTilaglisYP 230

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 805752155 220 LDVLKTRAM---NAKPGE---FKSLMDLFL-YTAKLGPLAFFKMA 257
Cdd:PTZ00169 231 FDTVRRRMMmmsGRKAKSeiqYTGTLDCWKkILKNEGLGGFFKGA 275
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 21-186 4.03e-04

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 42.99  E-value: 4.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  21 AACVTH-PLDLLKVHLQTQqeGKLSVVRLTTSIVKNQGILA-LYNGLSASLLRQLTYSTTRFGAYEV----GKQTFEKPG 94
Cdd:PTZ00168  97 TACIVRlPFEIVKQNMQVS--GNISVLKTIYEITQREGLPSfLGKSYFVMIVREIPFDCIQYFLWETlkekAKKDFGKFS 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805752155  95 HSLLFYQKLLLAGFSGAVGGVLGTPGDVINVRmqndiklapelRRNYKHALDGIVCIVQQEGFSKLFSGCttaTLRAALM 174
Cdd:PTZ00168 175 KKYPSITSAICGGLAGGIAGFLTTPVDVIKSR-----------QIIYGKSYIETVTEIAEEGYLTFYKGC---CFRSSYL 240

                        170
                 ....*....|..
gi 805752155 175 TIGQLSFYDQIK 186
Cdd:PTZ00168 241 FFGGLIFFGSLR 252
PRK10558 PRK10558
alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional
 507-568 1.89e-03

alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional


Pssm-ID: 182547  Cd Length: 256  Bit Score: 40.88  E-value: 1.89e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 805752155 507 KNIKIISKIENQQGMTNLDEI--IEASDGIMVARGDL-------GIEIPPEkVFLAQKCMISRCNKVGKPV 568
Cdd:PRK10558 144 KNITVLVQIESQQGVDNVDAIaaTEGVDGIFVGPSDLaaalghlGNASHPD-VQKAIQHIFARAKAHGKPS 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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