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Conserved domains on  [gi|1034634761|ref|XP_016862417|]
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sentrin-specific protease 7 isoform X7 [Homo sapiens]

Protein Classification

C48 family peptidase( domain architecture ID 581147)

C48 family peptidase similar to sentrin-specific proteases (SUMO proteases) that catalyze the processing of small ubiquitin-like modifier (SUMO) propeptides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_C48 super family cl23802
Ulp1 protease family, C-terminal catalytic domain; This domain contains the catalytic triad ...
 775-816 3.93e-05

Ulp1 protease family, C-terminal catalytic domain; This domain contains the catalytic triad Cys-His-Asn.


The actual alignment was detected with superfamily member pfam02902:

Pssm-ID: 420019  Cd Length: 202  Bit Score: 45.52  E-value: 3.93e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1034634761 775 EFLNDVIIDFYLKYLI-LEKASDELVERSHIFSSFFYKCLTRK 816
Cdd:pfam02902   1 EWLNDTVIDFYLKLLAhRLESEDYKNERVHFLNSFFYSKLTSK 43
 
Name Accession Description Interval E-value
Peptidase_C48 pfam02902
Ulp1 protease family, C-terminal catalytic domain; This domain contains the catalytic triad ...
 775-816 3.93e-05

Ulp1 protease family, C-terminal catalytic domain; This domain contains the catalytic triad Cys-His-Asn.


Pssm-ID: 397169  Cd Length: 202  Bit Score: 45.52  E-value: 3.93e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1034634761 775 EFLNDVIIDFYLKYLI-LEKASDELVERSHIFSSFFYKCLTRK 816
Cdd:pfam02902   1 EWLNDTVIDFYLKLLAhRLESEDYKNERVHFLNSFFYSKLTSK 43
PLN03189 PLN03189
Protease specific for SMALL UBIQUITIN-RELATED MODIFIER (SUMO); Provisional
 763-814 5.78e-03

Protease specific for SMALL UBIQUITIN-RELATED MODIFIER (SUMO); Provisional


Pssm-ID: 215622 [Multi-domain]  Cd Length: 490  Bit Score: 40.22  E-value: 5.78e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034634761 763 VTNEDLECLEEGEFLNDVIIDFYLKYLI-LEKASDELVERSHIFSSFFYKCLT 814
Cdd:PLN03189  290 ITGEILRCLKPGAWLNDEVINLYLELLKeREAREPKKFLKCHFFNTFFYKKLV 342
 
Name Accession Description Interval E-value
Peptidase_C48 pfam02902
Ulp1 protease family, C-terminal catalytic domain; This domain contains the catalytic triad ...
 775-816 3.93e-05

Ulp1 protease family, C-terminal catalytic domain; This domain contains the catalytic triad Cys-His-Asn.


Pssm-ID: 397169  Cd Length: 202  Bit Score: 45.52  E-value: 3.93e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1034634761 775 EFLNDVIIDFYLKYLI-LEKASDELVERSHIFSSFFYKCLTRK 816
Cdd:pfam02902   1 EWLNDTVIDFYLKLLAhRLESEDYKNERVHFLNSFFYSKLTSK 43
PLN03189 PLN03189
Protease specific for SMALL UBIQUITIN-RELATED MODIFIER (SUMO); Provisional
 763-814 5.78e-03

Protease specific for SMALL UBIQUITIN-RELATED MODIFIER (SUMO); Provisional


Pssm-ID: 215622 [Multi-domain]  Cd Length: 490  Bit Score: 40.22  E-value: 5.78e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034634761 763 VTNEDLECLEEGEFLNDVIIDFYLKYLI-LEKASDELVERSHIFSSFFYKCLT 814
Cdd:PLN03189  290 ITGEILRCLKPGAWLNDEVINLYLELLKeREAREPKKFLKCHFFNTFFYKKLV 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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