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Conserved domains on  [gi|1034578237|ref|XP_016874376|]
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uncharacterized protein C12orf50 isoform X3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF5571 pfam17732
Family of unknown function (DUF5571); This is a family of unknown function found in chordata. ...
120-468 0e+00

Family of unknown function (DUF5571); This is a family of unknown function found in chordata. Family members carry a zinc finger family on the N-terminal pfam15663.


:

Pssm-ID: 465475  Cd Length: 352  Bit Score: 611.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 120 LKPQENISRPIHHPLVLKTNFE---EEEEVDEQNDASSLWTKTPEEIEEKRAIKEMCYKSGEYYRFHTPPDILSSKSMTP 196
Cdd:pfam17732   1 LKPQENISRPIHPPLVININFEeeeEEEEEEKENDASSLWTKTPEDIEEERAIKEMCYKSGEYYRFHTPPDHQSTKSVSP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 197 TAEKQLEKPLENGSELQEGDSLTVPTKLSQYERQGEIKTSLHGKPKTDIAAFENGGGDCYVPQRVIFLGVDESEALTEEK 276
Cdd:pfam17732  81 SVEKELEKPLENGSDLQEGDGLTIPTKLNNFERQGETKISLDGKPRTDLAAFENGGGDCYVPQRIIFLGVDESEALTEEK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 277 EITISKCSNTKDNKDSPHPKHSLTTRLVPTTHVLNATENISMKCREDPSSMNDVQPVKKPHFKGVKKRKWIYDEPQNFPN 356
Cdd:pfam17732 161 EPIMSKYSNVKDIKDSPHPKHSVTTRLVPTTHVLNATENINMKCREDPSSMNDSQPVRKPHFKGVKKKKWIYEEPKNSPN 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 357 SGMQRAVQAPRPQNKMSYHRNNKNRNAENASYIHVQRDAVRTVALNAPSRSRPTHGSYNKVHANREPKPNLSPDKYTSTS 436
Cdd:pfam17732 241 PGTRKATQTPNPKNKMSYQRNDKNRNAENASYIHVVRQAVRNVYLNSPEPRRSANGFYNKVRVNKEPKFNLSPDKYSSTS 320
                         330       340       350
                  ....*....|....*....|....*....|..
gi 1034578237 437 YNDSAWRKRIPFSKTYSKSEKIYPEPRRNGSK 468
Cdd:pfam17732 321 YNAPTWRKRIPFSKTYSKFKKIYSEPRRNGSK 352
zf-CCCH_3 super family cl25863
Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically ...
1-99 4.08e-48

Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically between 155 and 169 amino acids in length.


The actual alignment was detected with superfamily member pfam15663:

Pssm-ID: 464787 [Multi-domain]  Cd Length: 110  Bit Score: 161.09  E-value: 4.08e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237   1 MAEVGNDCYFFFNSTCIKGSQCRFRHCEEALGSDTVCSLWRERKCLDPLCRFRHMEMQQNCS-ISCFWETQPLGCVKISC 79
Cdd:pfam15663   1 MENKGDDCYFFYYSTCTKGDSCPFRHCEAALGNETVCTLWQEGRCFRPVCRFRHMEIDKNRKeIPCYWENQPGGCQKPHC 80
                          90       100
                  ....*....|....*....|
gi 1034578237  80 IFYHSKPRNINGLFLPPSSN 99
Cdd:pfam15663  81 AFHHTKPRYVDGLFLPPSKT 100
 
Name Accession Description Interval E-value
DUF5571 pfam17732
Family of unknown function (DUF5571); This is a family of unknown function found in chordata. ...
120-468 0e+00

Family of unknown function (DUF5571); This is a family of unknown function found in chordata. Family members carry a zinc finger family on the N-terminal pfam15663.


Pssm-ID: 465475  Cd Length: 352  Bit Score: 611.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 120 LKPQENISRPIHHPLVLKTNFE---EEEEVDEQNDASSLWTKTPEEIEEKRAIKEMCYKSGEYYRFHTPPDILSSKSMTP 196
Cdd:pfam17732   1 LKPQENISRPIHPPLVININFEeeeEEEEEEKENDASSLWTKTPEDIEEERAIKEMCYKSGEYYRFHTPPDHQSTKSVSP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 197 TAEKQLEKPLENGSELQEGDSLTVPTKLSQYERQGEIKTSLHGKPKTDIAAFENGGGDCYVPQRVIFLGVDESEALTEEK 276
Cdd:pfam17732  81 SVEKELEKPLENGSDLQEGDGLTIPTKLNNFERQGETKISLDGKPRTDLAAFENGGGDCYVPQRIIFLGVDESEALTEEK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 277 EITISKCSNTKDNKDSPHPKHSLTTRLVPTTHVLNATENISMKCREDPSSMNDVQPVKKPHFKGVKKRKWIYDEPQNFPN 356
Cdd:pfam17732 161 EPIMSKYSNVKDIKDSPHPKHSVTTRLVPTTHVLNATENINMKCREDPSSMNDSQPVRKPHFKGVKKKKWIYEEPKNSPN 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 357 SGMQRAVQAPRPQNKMSYHRNNKNRNAENASYIHVQRDAVRTVALNAPSRSRPTHGSYNKVHANREPKPNLSPDKYTSTS 436
Cdd:pfam17732 241 PGTRKATQTPNPKNKMSYQRNDKNRNAENASYIHVVRQAVRNVYLNSPEPRRSANGFYNKVRVNKEPKFNLSPDKYSSTS 320
                         330       340       350
                  ....*....|....*....|....*....|..
gi 1034578237 437 YNDSAWRKRIPFSKTYSKSEKIYPEPRRNGSK 468
Cdd:pfam17732 321 YNAPTWRKRIPFSKTYSKFKKIYSEPRRNGSK 352
zf-CCCH_3 pfam15663
Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically ...
1-99 4.08e-48

Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically between 155 and 169 amino acids in length.


Pssm-ID: 464787 [Multi-domain]  Cd Length: 110  Bit Score: 161.09  E-value: 4.08e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237   1 MAEVGNDCYFFFNSTCIKGSQCRFRHCEEALGSDTVCSLWRERKCLDPLCRFRHMEMQQNCS-ISCFWETQPLGCVKISC 79
Cdd:pfam15663   1 MENKGDDCYFFYYSTCTKGDSCPFRHCEAALGNETVCTLWQEGRCFRPVCRFRHMEIDKNRKeIPCYWENQPGGCQKPHC 80
                          90       100
                  ....*....|....*....|
gi 1034578237  80 IFYHSKPRNINGLFLPPSSN 99
Cdd:pfam15663  81 AFHHTKPRYVDGLFLPPSKT 100
 
Name Accession Description Interval E-value
DUF5571 pfam17732
Family of unknown function (DUF5571); This is a family of unknown function found in chordata. ...
120-468 0e+00

Family of unknown function (DUF5571); This is a family of unknown function found in chordata. Family members carry a zinc finger family on the N-terminal pfam15663.


Pssm-ID: 465475  Cd Length: 352  Bit Score: 611.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 120 LKPQENISRPIHHPLVLKTNFE---EEEEVDEQNDASSLWTKTPEEIEEKRAIKEMCYKSGEYYRFHTPPDILSSKSMTP 196
Cdd:pfam17732   1 LKPQENISRPIHPPLVININFEeeeEEEEEEKENDASSLWTKTPEDIEEERAIKEMCYKSGEYYRFHTPPDHQSTKSVSP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 197 TAEKQLEKPLENGSELQEGDSLTVPTKLSQYERQGEIKTSLHGKPKTDIAAFENGGGDCYVPQRVIFLGVDESEALTEEK 276
Cdd:pfam17732  81 SVEKELEKPLENGSDLQEGDGLTIPTKLNNFERQGETKISLDGKPRTDLAAFENGGGDCYVPQRIIFLGVDESEALTEEK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 277 EITISKCSNTKDNKDSPHPKHSLTTRLVPTTHVLNATENISMKCREDPSSMNDVQPVKKPHFKGVKKRKWIYDEPQNFPN 356
Cdd:pfam17732 161 EPIMSKYSNVKDIKDSPHPKHSVTTRLVPTTHVLNATENINMKCREDPSSMNDSQPVRKPHFKGVKKKKWIYEEPKNSPN 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237 357 SGMQRAVQAPRPQNKMSYHRNNKNRNAENASYIHVQRDAVRTVALNAPSRSRPTHGSYNKVHANREPKPNLSPDKYTSTS 436
Cdd:pfam17732 241 PGTRKATQTPNPKNKMSYQRNDKNRNAENASYIHVVRQAVRNVYLNSPEPRRSANGFYNKVRVNKEPKFNLSPDKYSSTS 320
                         330       340       350
                  ....*....|....*....|....*....|..
gi 1034578237 437 YNDSAWRKRIPFSKTYSKSEKIYPEPRRNGSK 468
Cdd:pfam17732 321 YNAPTWRKRIPFSKTYSKFKKIYSEPRRNGSK 352
zf-CCCH_3 pfam15663
Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically ...
1-99 4.08e-48

Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically between 155 and 169 amino acids in length.


Pssm-ID: 464787 [Multi-domain]  Cd Length: 110  Bit Score: 161.09  E-value: 4.08e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034578237   1 MAEVGNDCYFFFNSTCIKGSQCRFRHCEEALGSDTVCSLWRERKCLDPLCRFRHMEMQQNCS-ISCFWETQPLGCVKISC 79
Cdd:pfam15663   1 MENKGDDCYFFYYSTCTKGDSCPFRHCEAALGNETVCTLWQEGRCFRPVCRFRHMEIDKNRKeIPCYWENQPGGCQKPHC 80
                          90       100
                  ....*....|....*....|
gi 1034578237  80 IFYHSKPRNINGLFLPPSSN 99
Cdd:pfam15663  81 AFHHTKPRYVDGLFLPPSKT 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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