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Conserved domains on  [gi|1034596434|ref|XP_016879308|]
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voltage-dependent T-type calcium channel subunit alpha-1H isoform X3 [Homo sapiens]

Protein Classification

ion transporter( domain architecture ID 11997982)

ion transporter such as a voltage-gated cation channel, which enables the selective translocation of cations such as sodium, calcium, or potassium, across cell membranes

Gene Ontology:  GO:0034220|GO:0005216
PubMed:  15816170
TCDB:  1.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 779-1006 1.38e-65

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 222.91  E-value: 1.38e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  779 SKYFSRGIMMAILVNTLSMGVEYHEQPEE-LTNALEISNIVFTSMFALEMLLKLLACGP-LGYIRNPYNIFDGIIVVISV 856
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  857 WEIV---GQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSlktD 933
Cdd:pfam00520   81 ISLVlssVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLK---T 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034596434  934 TGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSS-WAALYFVALMTFGNYVLFNLLVAILVEGFQ 1006
Cdd:pfam00520  158 WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEfWAYIYFVSFIILGGFLLLNLFIAVIIDNFQ 231
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1280-1552 5.13e-57

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 198.26  E-value: 5.13e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1280 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERvFLSVSNYIFTAIFVAEMMVKVVALGLLsgeHAYLQSSWNLLDGLLV 1359
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTT-VLEILDYVFTGIFTLEMLLKIIAAGFK---KRYFRSPWNILDFVVV 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1360 LVSLVDIVVAMASAGGA-------------KIlgvlrvlrllrtlrplrvISRAPGLKLVVETLISSLRPIGNIVLICCA 1426
Cdd:pfam00520   77 LPSLISLVLSSVGSLSGlrvlrllrllrllRL------------------IRRLEGLRTLVNSLIRSLKSLGNLLLLLLL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1427 FFIIFGILGVQLFKGKFYYCEGPDTRNistkaqcraahyrwvrrkYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGv 1506
Cdd:pfam00520  139 FLFIFAIIGYQLFGGKLKTWENPDNGR------------------TNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG- 199

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1034596434 1507 dqqpvqnhNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1552
Cdd:pfam00520  200 --------EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERT 237
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1608-1839 5.43e-52

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 183.62  E-value: 5.43e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1608 SHYLDLFITFIICVNVITMSMEHYNQPKS-LDEALKYCNYVFTIVFVFEAALKLVAFGF-RRFFKDRWNQLDLAIVLLSL 1685
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1686 MGITLEEIEmsaalpiNPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGR 1765
Cdd:pfam00520   81 ISLVLSSVG-------SLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGG 153

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034596434 1766 LECSEDNPCEGlsrHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSredkhclsylPALSPVYFVTFVLVA 1839
Cdd:pfam00520  154 KLKTWENPDNG---RTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG----------EFWAYIYFVSFIILG 214
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 99-417 3.17e-45

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 164.36  E-value: 3.17e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434   99 NPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNI----------LEMVIKMVALGLFgqKCYLGDTWNRLDFFIVVA 168
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTTVLEIldyvftgiftLEMLLKIIAAGFK--KRYFRSPWNILDFVVVLP 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  169 GMMEYSLDGHN--VSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFfvffifgivgvqlwagllrnr 246
Cdd:pfam00520   79 SLISLVLSSVGslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLL--------------------- 137

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  247 CFLdsafvrnnnltflrpyyqteegeenpFICSSrrdNGMQkcshipgrreLRMPCTLGWEaytqpqaegvgaarnacin 326
Cdd:pfam00520  138 LFL--------------------------FIFAI---IGYQ----------LFGGKLKTWE------------------- 159

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  327 wnqyynvcrsgdsNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA-HSFYNFIYFILLIIVGSFFMINLCLVVI 405
Cdd:pfam00520  160 -------------NPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGkGEFWAYIYFVSFIILGGFLLLNLFIAVI 226

                          330
                   ....*....|..
gi 1034596434  406 ATQFSETKQRES 417
Cdd:pfam00520  227 IDNFQELTERTE 238
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 1877-2344 5.71e-11

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 68.81  E-value: 5.71e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1877 AQGPGSARRVDADRPP---------LPQESPGARDAPNLVARKVSVSRMLSlpNDSYMFRPVVPASAPHPRPLQEVEMET 1947
Cdd:PHA03247  2495 APDPGGGGPPDPDAPPapsrlapaiLPDEPVGEPVHPRMLTWIRGLEELAS--DDAGDPPPPLPPAAPPAAPDRSVPPPR 2572

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1948 YG---AGTPLGSVASVHSPPAEScASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPR 2024
Cdd:PHA03247  2573 PAprpSEPAVTSRARRPDAPPQS-ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPER 2651

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2025 DTLDPAEPGEKTPVRPVTQGGSLQ--SPPRSPRPASVRTrkhTFGQRCVSSRPAAPGGEEAEASDPADEEV--------S 2094
Cdd:PHA03247  2652 PRDDPAPGRVSRPRRARRLGRAAQasSPPQRPRRRAARP---TVGSLTSLADPPPPPPTPEPAPHALVSATplppgpaaA 2728

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2095 HITSSACPWQPtAEPHGPEASPVAGGERDLRRLYSVDAqgfldkPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGAR 2174
Cdd:PHA03247  2729 RQASPALPAAP-APPAVPAGPATPGGPARPARPPTTAG------PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSP 2801

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2175 RKKkmSPPCISVEPPAEDE-GSARPSAAEGGSTTLRRRTPSCEATPHRDSLePTEGSGAGGDPAAKGERWGQASC----- 2248
Cdd:PHA03247  2802 WDP--ADPPAAVLAPAAALpPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRPPSRSPAAkpaap 2878

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2249 ---RAEHLTVPSFAFEPLDLGVPSGDPfldgSHSVTPESRASSsgaivplEPPESEPPMPVGDPPEKRRGLyltvPQCPL 2325
Cdd:PHA03247  2879 arpPVRRLARPAVSRSTESFALPPDQP----ERPPQPQAPPPP-------QPQPQPPPPPQPQPPPPPPPR----PQPPL 2943

                          490
                   ....*....|....*....
gi 1034596434 2326 EKPGSPSATPAPGGGADDP 2344
Cdd:PHA03247  2944 APTTDPAGAGEPSGAVPQP 2962
 
Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 779-1006 1.38e-65

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 222.91  E-value: 1.38e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  779 SKYFSRGIMMAILVNTLSMGVEYHEQPEE-LTNALEISNIVFTSMFALEMLLKLLACGP-LGYIRNPYNIFDGIIVVISV 856
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  857 WEIV---GQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSlktD 933
Cdd:pfam00520   81 ISLVlssVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLK---T 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034596434  934 TGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSS-WAALYFVALMTFGNYVLFNLLVAILVEGFQ 1006
Cdd:pfam00520  158 WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEfWAYIYFVSFIILGGFLLLNLFIAVIIDNFQ 231
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1280-1552 5.13e-57

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 198.26  E-value: 5.13e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1280 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERvFLSVSNYIFTAIFVAEMMVKVVALGLLsgeHAYLQSSWNLLDGLLV 1359
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTT-VLEILDYVFTGIFTLEMLLKIIAAGFK---KRYFRSPWNILDFVVV 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1360 LVSLVDIVVAMASAGGA-------------KIlgvlrvlrllrtlrplrvISRAPGLKLVVETLISSLRPIGNIVLICCA 1426
Cdd:pfam00520   77 LPSLISLVLSSVGSLSGlrvlrllrllrllRL------------------IRRLEGLRTLVNSLIRSLKSLGNLLLLLLL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1427 FFIIFGILGVQLFKGKFYYCEGPDTRNistkaqcraahyrwvrrkYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGv 1506
Cdd:pfam00520  139 FLFIFAIIGYQLFGGKLKTWENPDNGR------------------TNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG- 199

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1034596434 1507 dqqpvqnhNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1552
Cdd:pfam00520  200 --------EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERT 237
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1608-1839 5.43e-52

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 183.62  E-value: 5.43e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1608 SHYLDLFITFIICVNVITMSMEHYNQPKS-LDEALKYCNYVFTIVFVFEAALKLVAFGF-RRFFKDRWNQLDLAIVLLSL 1685
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1686 MGITLEEIEmsaalpiNPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGR 1765
Cdd:pfam00520   81 ISLVLSSVG-------SLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGG 153

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034596434 1766 LECSEDNPCEGlsrHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSredkhclsylPALSPVYFVTFVLVA 1839
Cdd:pfam00520  154 KLKTWENPDNG---RTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG----------EFWAYIYFVSFIILG 214
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 99-417 3.17e-45

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 164.36  E-value: 3.17e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434   99 NPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNI----------LEMVIKMVALGLFgqKCYLGDTWNRLDFFIVVA 168
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTTVLEIldyvftgiftLEMLLKIIAAGFK--KRYFRSPWNILDFVVVLP 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  169 GMMEYSLDGHN--VSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFfvffifgivgvqlwagllrnr 246
Cdd:pfam00520   79 SLISLVLSSVGslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLL--------------------- 137

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  247 CFLdsafvrnnnltflrpyyqteegeenpFICSSrrdNGMQkcshipgrreLRMPCTLGWEaytqpqaegvgaarnacin 326
Cdd:pfam00520  138 LFL--------------------------FIFAI---IGYQ----------LFGGKLKTWE------------------- 159

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  327 wnqyynvcrsgdsNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA-HSFYNFIYFILLIIVGSFFMINLCLVVI 405
Cdd:pfam00520  160 -------------NPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGkGEFWAYIYFVSFIILGGFLLLNLFIAVI 226

                          330
                   ....*....|..
gi 1034596434  406 ATQFSETKQRES 417
Cdd:pfam00520  227 IDNFQELTERTE 238
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1877-2344 5.71e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 68.81  E-value: 5.71e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1877 AQGPGSARRVDADRPP---------LPQESPGARDAPNLVARKVSVSRMLSlpNDSYMFRPVVPASAPHPRPLQEVEMET 1947
Cdd:PHA03247  2495 APDPGGGGPPDPDAPPapsrlapaiLPDEPVGEPVHPRMLTWIRGLEELAS--DDAGDPPPPLPPAAPPAAPDRSVPPPR 2572

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1948 YG---AGTPLGSVASVHSPPAEScASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPR 2024
Cdd:PHA03247  2573 PAprpSEPAVTSRARRPDAPPQS-ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPER 2651

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2025 DTLDPAEPGEKTPVRPVTQGGSLQ--SPPRSPRPASVRTrkhTFGQRCVSSRPAAPGGEEAEASDPADEEV--------S 2094
Cdd:PHA03247  2652 PRDDPAPGRVSRPRRARRLGRAAQasSPPQRPRRRAARP---TVGSLTSLADPPPPPPTPEPAPHALVSATplppgpaaA 2728

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2095 HITSSACPWQPtAEPHGPEASPVAGGERDLRRLYSVDAqgfldkPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGAR 2174
Cdd:PHA03247  2729 RQASPALPAAP-APPAVPAGPATPGGPARPARPPTTAG------PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSP 2801

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2175 RKKkmSPPCISVEPPAEDE-GSARPSAAEGGSTTLRRRTPSCEATPHRDSLePTEGSGAGGDPAAKGERWGQASC----- 2248
Cdd:PHA03247  2802 WDP--ADPPAAVLAPAAALpPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRPPSRSPAAkpaap 2878

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2249 ---RAEHLTVPSFAFEPLDLGVPSGDPfldgSHSVTPESRASSsgaivplEPPESEPPMPVGDPPEKRRGLyltvPQCPL 2325
Cdd:PHA03247  2879 arpPVRRLARPAVSRSTESFALPPDQP----ERPPQPQAPPPP-------QPQPQPPPPPQPQPPPPPPPR----PQPPL 2943

                          490
                   ....*....|....*....
gi 1034596434 2326 EKPGSPSATPAPGGGADDP 2344
Cdd:PHA03247  2944 APTTDPAGAGEPSGAVPQP 2962
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 2022-2178 7.61e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 44.37  E-value: 7.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2022 SPRDtlDPA----EPGEKTPVRPVTQGGSLQSPPRSPRPASVrtrkhtfgqrcvsSRPAAPGGEEAEASDPADEEVSHIT 2097
Cdd:NF040712   178 TALD--DEArwliDPDFGRPLRPLATVPRLAREPADARPEEV-------------EPAPAAEGAPATDSDPAEAGTPDDL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2098 SSA-----CPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQW-RPSAELGSGEPGEAKAWGPEAEPAL 2171
Cdd:NF040712   243 ASArrrraGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPApAPAAPAAPAAPEAEEPARPEPPPAP 322


                   ....*..
gi 1034596434 2172 GARRKKK 2178
Cdd:NF040712   323 KPKRRRR 329
 
Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 779-1006 1.38e-65

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 222.91  E-value: 1.38e-65
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  779 SKYFSRGIMMAILVNTLSMGVEYHEQPEE-LTNALEISNIVFTSMFALEMLLKLLACGP-LGYIRNPYNIFDGIIVVISV 856
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  857 WEIV---GQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSlktD 933
Cdd:pfam00520   81 ISLVlssVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLK---T 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034596434  934 TGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSS-WAALYFVALMTFGNYVLFNLLVAILVEGFQ 1006
Cdd:pfam00520  158 WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEfWAYIYFVSFIILGGFLLLNLFIAVIIDNFQ 231
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1280-1552 5.13e-57

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 198.26  E-value: 5.13e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1280 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERvFLSVSNYIFTAIFVAEMMVKVVALGLLsgeHAYLQSSWNLLDGLLV 1359
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTT-VLEILDYVFTGIFTLEMLLKIIAAGFK---KRYFRSPWNILDFVVV 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1360 LVSLVDIVVAMASAGGA-------------KIlgvlrvlrllrtlrplrvISRAPGLKLVVETLISSLRPIGNIVLICCA 1426
Cdd:pfam00520   77 LPSLISLVLSSVGSLSGlrvlrllrllrllRL------------------IRRLEGLRTLVNSLIRSLKSLGNLLLLLLL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1427 FFIIFGILGVQLFKGKFYYCEGPDTRNistkaqcraahyrwvrrkYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGv 1506
Cdd:pfam00520  139 FLFIFAIIGYQLFGGKLKTWENPDNGR------------------TNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG- 199

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1034596434 1507 dqqpvqnhNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQ 1552
Cdd:pfam00520  200 --------EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERT 237
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 1608-1839 5.43e-52

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 183.62  E-value: 5.43e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1608 SHYLDLFITFIICVNVITMSMEHYNQPKS-LDEALKYCNYVFTIVFVFEAALKLVAFGF-RRFFKDRWNQLDLAIVLLSL 1685
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1686 MGITLEEIEmsaalpiNPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGR 1765
Cdd:pfam00520   81 ISLVLSSVG-------SLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGG 153

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034596434 1766 LECSEDNPCEGlsrHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSredkhclsylPALSPVYFVTFVLVA 1839
Cdd:pfam00520  154 KLKTWENPDNG---RTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG----------EFWAYIYFVSFIILG 214
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 99-417 3.17e-45

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 164.36  E-value: 3.17e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434   99 NPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNI----------LEMVIKMVALGLFgqKCYLGDTWNRLDFFIVVA 168
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTTVLEIldyvftgiftLEMLLKIIAAGFK--KRYFRSPWNILDFVVVLP 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  169 GMMEYSLDGHN--VSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFfvffifgivgvqlwagllrnr 246
Cdd:pfam00520   79 SLISLVLSSVGslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLL--------------------- 137

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  247 CFLdsafvrnnnltflrpyyqteegeenpFICSSrrdNGMQkcshipgrreLRMPCTLGWEaytqpqaegvgaarnacin 326
Cdd:pfam00520  138 LFL--------------------------FIFAI---IGYQ----------LFGGKLKTWE------------------- 159

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  327 wnqyynvcrsgdsNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDA-HSFYNFIYFILLIIVGSFFMINLCLVVI 405
Cdd:pfam00520  160 -------------NPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGkGEFWAYIYFVSFIILGGFLLLNLFIAVI 226

                          330
                   ....*....|..
gi 1034596434  406 ATQFSETKQRES 417
Cdd:pfam00520  227 IDNFQELTERTE 238
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1877-2344 5.71e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 68.81  E-value: 5.71e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1877 AQGPGSARRVDADRPP---------LPQESPGARDAPNLVARKVSVSRMLSlpNDSYMFRPVVPASAPHPRPLQEVEMET 1947
Cdd:PHA03247  2495 APDPGGGGPPDPDAPPapsrlapaiLPDEPVGEPVHPRMLTWIRGLEELAS--DDAGDPPPPLPPAAPPAAPDRSVPPPR 2572

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1948 YG---AGTPLGSVASVHSPPAEScASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPR 2024
Cdd:PHA03247  2573 PAprpSEPAVTSRARRPDAPPQS-ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPER 2651

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2025 DTLDPAEPGEKTPVRPVTQGGSLQ--SPPRSPRPASVRTrkhTFGQRCVSSRPAAPGGEEAEASDPADEEV--------S 2094
Cdd:PHA03247  2652 PRDDPAPGRVSRPRRARRLGRAAQasSPPQRPRRRAARP---TVGSLTSLADPPPPPPTPEPAPHALVSATplppgpaaA 2728

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2095 HITSSACPWQPtAEPHGPEASPVAGGERDLRRLYSVDAqgfldkPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGAR 2174
Cdd:PHA03247  2729 RQASPALPAAP-APPAVPAGPATPGGPARPARPPTTAG------PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSP 2801

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2175 RKKkmSPPCISVEPPAEDE-GSARPSAAEGGSTTLRRRTPSCEATPHRDSLePTEGSGAGGDPAAKGERWGQASC----- 2248
Cdd:PHA03247  2802 WDP--ADPPAAVLAPAAALpPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRPPSRSPAAkpaap 2878

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2249 ---RAEHLTVPSFAFEPLDLGVPSGDPfldgSHSVTPESRASSsgaivplEPPESEPPMPVGDPPEKRRGLyltvPQCPL 2325
Cdd:PHA03247  2879 arpPVRRLARPAVSRSTESFALPPDQP----ERPPQPQAPPPP-------QPQPQPPPPPQPQPPPPPPPR----PQPPL 2943

                          490
                   ....*....|....*....
gi 1034596434 2326 EKPGSPSATPAPGGGADDP 2344
Cdd:PHA03247  2944 APTTDPAGAGEPSGAVPQP 2962
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1875-2272 2.98e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 62.88  E-value: 2.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1875 EMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGtPL 1954
Cdd:PHA03307    49 ELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPAS-PP 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1955 GSVASVHSPPAESCASLQIPLAVSSPArSGEPlHALSPRGTARSPSLSRLLCR-QEAVHTdslegkIDSPRDTLDPAEPG 2033
Cdd:PHA03307   128 PSPAPDLSEMLRPVGSPGPPPAASPPA-AGAS-PAAVASDAASSRQAALPLSSpEETARA------PSSPPAEPPPSTPP 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2034 EKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPG----GEEAEASDPADEEVSHITS--SACPWQPTA 2107
Cdd:PHA03307   200 AAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSgcgwGPENECPLPRPAPITLPTRiwEASGWNGPS 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2108 EPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAELG------SGEPGEAKAWGPEAEPALGARRKKKmSP 2181
Cdd:PHA03307   280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSssstssSSESSRGAAVSPGPSPSRSPSPSRP-PP 358

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2182 PCISVEPPAEDEGSARPS--AAEGGSTTLRRRTPSC-EATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRaehltvpsf 2258
Cdd:PHA03307   359 PADPSSPRKRPRPSRAPSspAASAGRPTRRRARAAVaGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR--------- 429

                          410
                   ....*....|....
gi 1034596434 2259 afEPldLGVPSGDP 2272
Cdd:PHA03307   430 --YP--LLTPSGEP 439
PKD_channel pfam08016
Polycystin cation channel; This family contains the cation channel region from group II of ...
 1646-1838 6.03e-07

Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins.


Pssm-ID: 462341 [Multi-domain]  Cd Length: 225  Bit Score: 52.66  E-value: 6.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1646 YVFTIVFVFEAALKLVAFGfRRFFKDRWNQLDLAIVLLS----------------LMGITLEEIE--------------- 1694
Cdd:pfam08016   18 VVFFLYFVVEEILKIRKHR-PSYLRSVWNLLDLAIVILSvvlivlniyrdfladrLIKSVEASPVtfidfdrvaqldnly 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1695 -MSAALPINPTIIRIMRVLRIARVLKLLKmatgmrallDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGrlecsednp 1773
Cdd:pfam08016   97 rIILAFLVFLTWLKLFKVLRFNKTMSLFT---------KTLSRAWKDLAGFALMFVIFFFAYAQFGYLLFG--------- 158

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034596434 1774 ceglSRHATFSNFGMAFLTLFRVSTGD-NWNGImkdtlRECSRedkhclsylpALSPVYFVTFVLV 1838
Cdd:pfam08016  159 ----TQAPNFSNFVKSILTLFRTILGDfGYNEI-----FSGNR----------VLGPLLFLTFVFL 205
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1957-2343 1.10e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 54.41  E-value: 1.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1957 VASVHSPPAESCASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEPGEKT 2036
Cdd:PHA03307    51 AAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSP 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2037 PVRpvtqggsLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEEVShitSSACPWQPTAEPhgPEASP 2116
Cdd:PHA03307   131 APD-------LSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEE---TARAPSSPPAEP--PPSTP 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2117 VAGGERDLRRLYSVDAQGFLD---KPGRADEQWRP-SAELGSGEPGEAKAWGPEAE-----PALGARRKKKM-------- 2179
Cdd:PHA03307   199 PAAASPRPPRRSSPISASASSpapAPGRSAADDAGaSSSDSSSSESSGCGWGPENEcplprPAPITLPTRIWeasgwngp 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2180 ---SPPCISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGErwGQASCRAehltvp 2256
Cdd:PHA03307   279 ssrPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSP--GPSPSRS------ 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2257 sfafepldlGVPSGDPfldGSHSVTPESRASSSGAIVPLEPPESeppmpvGDPPEKRRGLYLTVPQCPLEKPGS-PSATP 2335
Cdd:PHA03307   351 ---------PSPSRPP---PPADPSSPRKRPRPSRAPSSPAASA------GRPTRRRARAAVAGRARRRDATGRfPAGRP 412


                   ....*...
gi 1034596434 2336 APGGGADD 2343
Cdd:PHA03307   413 RPSPLDAG 420
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1884-2310 3.81e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 3.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1884 RRVDADRPPLPQESPGARDAPNLVARKVSVSRmlslPNDSymfrPVVPASAPHP----RPLQEVEmETYGAGTPLGSVAS 1959
Cdd:PHA03247  2669 RLGRAAQASSPPQRPRRRAARPTVGSLTSLAD----PPPP----PPTPEPAPHAlvsaTPLPPGP-AAARQASPALPAAP 2739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1960 VHSPPAESCASLQIPLAVSSPARSGEPLHALSPRGTARSPSlsRLLCRQEAVHTDSLEGKIDSPRDTLDP--AEPGEKTP 2037
Cdd:PHA03247  2740 APPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPP--RRLTRPAVASLSESRESLPSPWDPADPpaAVLAPAAA 2817

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2038 VRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASdpadeevshiTSSACPWQPTAEPHgPEASPV 2117
Cdd:PHA03247  2818 LPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRP----------PSRSPAAKPAAPAR-PPVRRL 2886

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2118 AggerdlRRLYSVDAQGFLDKPgraDEQWRPSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPcisVEPPAEDEGSAR 2197
Cdd:PHA03247  2887 A------RPAVSRSTESFALPP---DQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP---LAPTTDPAGAGE 2954

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2198 PSAAE-----GGSTTLRRRTPSCEATPHRDSLEPTEGSGAG--GDPAAKGERWgqASCRAEHL-TVPSFAFEPLDLGVPS 2269
Cdd:PHA03247  2955 PSGAVpqpwlGALVPGRVAVPRFRVPQPAPSREAPASSTPPltGHSLSRVSSW--ASSLALHEeTDPPPVSLKQTLWPPD 3032

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1034596434 2270 GDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPP 2310
Cdd:PHA03247  3033 DTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPA 3073
dnaA PRK14086
chromosomal replication initiator protein DnaA;
2026-2231 1.11e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 47.51  E-value: 1.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2026 TLDPA--EPGEKTPVRPVTQGGSLQSPPRSP------RPASVRTRKHTFGQRCVSSRPAAPggEEAEASDPAdeevshit 2097
Cdd:PRK14086    87 TVDPSagEPAPPPPHARRTSEPELPRPGRRPyegyggPRADDRPPGLPRQDQLPTARPAYP--AYQQRPEPG-------- 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2098 ssacPWQPTAEPHGPEASPVAGGERDlrrLYSVDAQgfldkPGRADEQWRPSAelGSGEPGEAKAWGPEAEPALGARRKK 2177
Cdd:PRK14086   157 ----AWPRAADDYGWQQQRLGFPPRA---PYASPAS-----YAPEQERDREPY--DAGRPEYDQRRRDYDHPRPDWDRPR 222

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1034596434 2178 KMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSlEPTEGSG 2231
Cdd:PRK14086   223 RDRTDRPEPPPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQP-APAPGPG 275
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 1927-2345 1.62e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.90  E-value: 1.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1927 RPVVPASAPHPRP-LQEVEMETYGAGTPLGSVASVHSPPAESCASLQIPLAVSSPARSGEPLHALSPR-GTARSPSlsrl 2004
Cdd:PRK07764   361 RMLLPSASDDERGlLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAApQPAPAPA---- 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2005 lcrQEAVHTDSLEGKIDSPRDTLDPAEPGEKTPvRPVTQGGSLQSPPRSPRPASVRTRkhtfgqrcvSSRPAAPGGEEAE 2084
Cdd:PRK07764   437 ---PAPAPPSPAGNAPAGGAPSPPPAAAPSAQP-APAPAAAPEPTAAPAPAPPAAPAP---------AAAPAAPAAPAAP 503

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2085 ASDPADEEV------------SHITSSACPWQPTAEPHGPEaspvaGGERDLRRLYSVDAQGFLDkPGRAD--------- 2143
Cdd:PRK07764   504 AGADDAATLrerwpeilaavpKRSRKTWAILLPEATVLGVR-----GDTLVLGFSTGGLARRFAS-PGNAEvlvtalaee 577

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2144 --EQWRPSAELGsGEPGEAKAWGPEAePALGARRKKKMSPPciSVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHR 2221
Cdd:PRK07764   578 lgGDWQVEAVVG-PAPGAAGGEGPPA-PASSGPPEEAARPA--APAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHH 653

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2222 DSLEPTEGSGAGGDPAAKGERWGQASCRAehlTVPSFAFEPLDLGVPSGDPfLDGSHSVTPESRASSSGAIVPLEPPESE 2301
Cdd:PRK07764   654 PKHVAVPDASDGGDGWPAKAGGAAPAAPP---PAPAPAAPAAPAGAAPAQP-APAPAATPPAGQADDPAAQPPQAAQGAS 729

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034596434 2302 PPMPVGD-----------PPEKRRGLYLTVPQCPLEKPGSPSATPAPGGGADDPV 2345
Cdd:PRK07764   730 APSPAADdpvplppepddPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEE 784
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2069-2263 6.88e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.87  E-value: 6.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2069 RCVSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLdKPGRADEQWRP 2148
Cdd:PRK12323   359 RMLAFRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARR-SPAPEALAAAR 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2149 SAELGSGEPGEAKAWGPEAEPALGARrkkkmsPPCISVEPPAEDEGSARPSAAEGGSttlrrRTPSCEATPHRDSLEPTE 2228
Cdd:PRK12323   438 QASARGPGGAPAPAPAPAAAPAAAAR------PAAAGPRPVAAAAAAAPARAAPAAA-----PAPADDDPPPWEELPPEF 506

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1034596434 2229 GSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPL 2263
Cdd:PRK12323   507 ASPAPAQPDAAPAGWVAESIPDPATADPDDAFETL 541
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 2022-2178 7.61e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 44.37  E-value: 7.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2022 SPRDtlDPA----EPGEKTPVRPVTQGGSLQSPPRSPRPASVrtrkhtfgqrcvsSRPAAPGGEEAEASDPADEEVSHIT 2097
Cdd:NF040712   178 TALD--DEArwliDPDFGRPLRPLATVPRLAREPADARPEEV-------------EPAPAAEGAPATDSDPAEAGTPDDL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2098 SSA-----CPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQW-RPSAELGSGEPGEAKAWGPEAEPAL 2171
Cdd:NF040712   243 ASArrrraGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPApAPAAPAAPAAPEAEEPARPEPPPAP 322


                   ....*..
gi 1034596434 2172 GARRKKK 2178
Cdd:NF040712   323 KPKRRRR 329
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 1877-2225 7.76e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.98  E-value: 7.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1877 AQGPGSARRVDADRPPlPQESPGARDAPNLVARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGS 1956
Cdd:PRK07764   409 APAPAAAAPAAAAAPA-PAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAA 487

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1957 VASVHSPPAESCASLQI-PLAVSSPARSGEPL-------------------HALSPRGTA-----RSPSLSRLLCRQEav 2011
Cdd:PRK07764   488 PAPAAAPAAPAAPAAPAgADDAATLRERWPEIlaavpkrsrktwaillpeaTVLGVRGDTlvlgfSTGGLARRFASPG-- 565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2012 HTDSL--------------EGKIDSPRDTLDPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRK--HTFGQRCVSSRP 2075
Cdd:PRK07764   566 NAEVLvtalaeelggdwqvEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGaaAAPAEASAAPAP 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2076 AAPGGE---EAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRlYSVDAQGFLDKPGRADEQW--RPSA 2150
Cdd:PRK07764   646 GVAAPEhhpKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPA-QPAPAPAATPPAGQADDPAaqPPQA 724

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034596434 2151 ELGSGEPGEAKAWG----PEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLE 2225
Cdd:PRK07764   725 AQGASAPSPAADDPvplpPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEE 803
PHA03309 PHA03309
transcriptional regulator ICP4; Provisional
 1931-2310 9.18e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 165564 [Multi-domain]  Cd Length: 2033  Bit Score: 44.84  E-value: 9.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1931 PASAPHPRPLQ---EVEMETYGAGTPLGSvaSVHSPPAESCASLQIPLAVSSPARSGEPLHALSP--RGTARSPS----- 2000
Cdd:PHA03309  1535 PAAPPGPELADrhaDRRRSTKGPQRPGGK--RPRSSSSSSSASHDRSPSSSSRRRDGRPSSRRRPsrRMSARPPSrppaa 1612

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2001 ------------LSRLLCRQEAVHTDSLEGKidsprDTLDPAEPGEKtPVRPVT-------QGGSLQSPPRSPRPASvrt 2061
Cdd:PHA03309  1613 vilraswryaeeVAREMLDAAASRFDEADGE-----DPLPPAACGGK-PIAPETlvalceqRGRGPTSLPRAPTPRS--- 1683

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2062 rkhtfGQRCVSSRPAApggeeaeASDPADEEVshitssaCPWQPTAE-PHGPEASPVAggERDLRRLYSVDAQGFLD--- 2137
Cdd:PHA03309  1684 -----GEALAAPRRSG-------AKDPRQGQY-------CPSARRSEaPHSPSPRDVA--LRLLERQQELNRQLLLElrr 1742

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2138 -------KPGRADEQWRPSAELGSGEPGEAKAWGPEA-EPALGARRKKKMSPPC--------------ISV-EPPAEDEG 2194
Cdd:PHA03309  1743 gsceispSPRRRDAEGRRFGCRQDDDDGYDYEGGRESpERVLGRRQSRRDSVPVrrrsgaancggrwmISAgRSSSSSSS 1822

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2195 SARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAG-----GDPAAKGERWG-QASCRAEHL---TVPSFAFEPLDL 2265
Cdd:PHA03309  1823 SSSSSSSSPSSRPSRSATPSLSPSPSPPRRAPVDRSRSGrrrerDRPSANPFRWApRQRSRADHSpdgTAPGDAPLNLED 1902

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1034596434 2266 GVPSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPP 2310
Cdd:PHA03309  1903 GPGRGRPIWTPSSATTLPSRSGPEDSVDETETEDSAPPARLAPSP 1947
PHA03378 PHA03378
EBNA-3B; Provisional
 1952-2340 1.27e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 44.29  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1952 TPLGSVASV--HSPPAESCASLQIPLAVSSPARSGEPLhalsprgtaRSPSLSRLLCRQEAVHTDSLEGKIdsprdtLDP 2029
Cdd:PHA03378   444 TPHSQAPTVvlHRPPTQPLEGPTGPLSVQAPLEPWQPL---------PHPQVTPVILHQPPAQGVQAHGSM------LDL 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2030 AEPGEKTPVRPVTqggSLQSPPRSPRPASVRTRKHTFGQR--CVSSRPA-----------APGGEEAEASDPADEEVSHI 2096
Cdd:PHA03378   509 LEKDDEDMEQRVM---ATLLPPSPPQPRAGRRAPCVYTEDldIESDEPAstepvhdqllpAPGLGPLQIQPLTSPTTSQL 585

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2097 TSSA-----CPW---QPTAEPHGPEASPVAGGERDLRR----LYSVDAQGFLDKPGRADEQWRPSAElgsgepgeakaWG 2164
Cdd:PHA03378   586 ASSApsyaqTPWpvpHPSQTPEPPTTQSHIPETSAPRQwpmpLRPIPMRPLRMQPITFNVLVFPTPH-----------QP 654

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2165 PEAEPALgaRRKKKMSPPCISVEP-PAEDEGSARPSAAEGgsttlRRRTPSCEATPHRdslePTEGsgaggdPAAKGERW 2243
Cdd:PHA03378   655 PQVEITP--YKPTWTQIGHIPYQPsPTGANTMLPIQWAPG-----TMQPPPRAPTPMR----PPAA------PPGRAQRP 717

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2244 GQASCRAehltvPSFAFEPLDLGVPSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKrrglyltVPQC 2323
Cdd:PHA03378   718 AAATGRA-----RPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQ-------APPA 785

                          410
                   ....*....|....*...
gi 1034596434 2324 PLEKP-GSPSATPAPGGG 2340
Cdd:PHA03378   786 PQQRPrGAPTPQPPPQAG 803
PKD_channel pfam08016
Polycystin cation channel; This family contains the cation channel region from group II of ...
 862-1005 1.56e-03

Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins.


Pssm-ID: 462341 [Multi-domain]  Cd Length: 225  Bit Score: 42.26  E-value: 1.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434  862 QADGGLSVLRTFRLLRVLKLVRFlpalRRQLVVLVKTM----DNVATFCTLLMLFIFIFSILGMHLFGCKFSlktdtgdt 937
Cdd:pfam08016   95 LYRIILAFLVFLTWLKLFKVLRF----NKTMSLFTKTLsrawKDLAGFALMFVIFFFAYAQFGYLLFGTQAP-------- 162

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034596434  938 vpdrkNFDSLLWAIVTVFQILtqedWNVVLYNGMASTSSW-AALYFVALMTFGNYVLFNLLVAILVEGF 1005
Cdd:pfam08016  163 -----NFSNFVKSILTLFRTI----LGDFGYNEIFSGNRVlGPLLFLTFVFLVIFILLNLFLAIINDSY 222
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1991-2247 3.13e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.91  E-value: 3.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 1991 SPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEPGEKTPvRPVTQGGS--LQSPPRSPRPASVRTR--KHTF 2066
Cdd:PRK07003   366 GAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAP-KAAAAAAAtrAEAPPAAPAPPATADRgdDAAD 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2067 GQRCVSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGfLDKPGRADE-- 2144
Cdd:PRK07003   445 GDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARA-PAAASREDApa 523

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034596434 2145 -QWRPSAELGSGEPGEAK--AWGPEAEPALGARRKKKMSppcISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHR 2221
Cdd:PRK07003   524 aAAPPAPEARPPTPAAAApaARAGGAAAALDVLRNAGMR---VSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPR 600

                          250       260
                   ....*....|....*....|....*.
gi 1034596434 2222 DSLEPTEGSGAGGDPAAKGERWGQAS 2247
Cdd:PRK07003   601 ARAATGDAPPNGAARAEQAAESRGAP 626
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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