NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1034610226|ref|XP_016883007|]
View 

zinc finger protein 254 isoform X3 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
191-552 6.94e-11

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 64.72  E-value: 6.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 191 KLYKCEECGEAFNRSSNLTTHKIIHTGEKPYKC--EECGKAFIWSSTLTEHKKIHTRKKPYKCE-ECGKAFIWSSTLTRH 267
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 268 KRMHTGEKPYKCEECGKAFSQSSTLT--THKIIHTGEKRYK---------------------CLECGKAFKQLSTLTTHK 324
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgnnsssvntpqsnslhpplpaNSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 325 IIHVGEKLYKCEECGKgFNRSSNLTTHKIIHTGEKPYKCEECGKAF-----IWSSTLTKHKRIHTREKP-YKCEECGKAF 398
Cdd:COG5048   192 VSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllSQSPSSLSSSDSSSSASEsPRSSLPTASS 270

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 399 IWSSTLTRHKRMHTG-EKPYKCEECGKSFSQSSTLTTHK--IIHTGE--KPYKCEE--CGKAFNWSSTLTKHKIIHTEEK 471
Cdd:COG5048   271 QSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSIS 350

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 472 PYKC--EKCGKAFKQSSI-----LTNHKRIHTGEKPYKCE--ECGKSFNRSSTFTKHKVIHTGVKP--YKCEECGKAFFW 540
Cdd:COG5048   351 PAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNR 430

                         410
                  ....*....|..
gi 1034610226 541 SSTLTKHKRIHT 552
Cdd:COG5048   431 HYNLIPHKKIHT 442
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
191-552 6.94e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 64.72  E-value: 6.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 191 KLYKCEECGEAFNRSSNLTTHKIIHTGEKPYKC--EECGKAFIWSSTLTEHKKIHTRKKPYKCE-ECGKAFIWSSTLTRH 267
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 268 KRMHTGEKPYKCEECGKAFSQSSTLT--THKIIHTGEKRYK---------------------CLECGKAFKQLSTLTTHK 324
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgnnsssvntpqsnslhpplpaNSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 325 IIHVGEKLYKCEECGKgFNRSSNLTTHKIIHTGEKPYKCEECGKAF-----IWSSTLTKHKRIHTREKP-YKCEECGKAF 398
Cdd:COG5048   192 VSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllSQSPSSLSSSDSSSSASEsPRSSLPTASS 270

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 399 IWSSTLTRHKRMHTG-EKPYKCEECGKSFSQSSTLTTHK--IIHTGE--KPYKCEE--CGKAFNWSSTLTKHKIIHTEEK 471
Cdd:COG5048   271 QSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSIS 350

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 472 PYKC--EKCGKAFKQSSI-----LTNHKRIHTGEKPYKCE--ECGKSFNRSSTFTKHKVIHTGVKP--YKCEECGKAFFW 540
Cdd:COG5048   351 PAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNR 430

                         410
                  ....*....|..
gi 1034610226 541 SSTLTKHKRIHT 552
Cdd:COG5048   431 HYNLIPHKKIHT 442
zf-H2C2_2 pfam13465
Zinc-finger double domain;
404-428 1.44e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 1.44e-04
                          10        20
                  ....*....|....*....|....*
gi 1034610226 404 LTRHKRMHTGEKPYKCEECGKSFSQ 428
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
191-552 6.94e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 64.72  E-value: 6.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 191 KLYKCEECGEAFNRSSNLTTHKIIHTGEKPYKC--EECGKAFIWSSTLTEHKKIHTRKKPYKCE-ECGKAFIWSSTLTRH 267
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 268 KRMHTGEKPYKCEECGKAFSQSSTLT--THKIIHTGEKRYK---------------------CLECGKAFKQLSTLTTHK 324
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgnnsssvntpqsnslhpplpaNSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 325 IIHVGEKLYKCEECGKgFNRSSNLTTHKIIHTGEKPYKCEECGKAF-----IWSSTLTKHKRIHTREKP-YKCEECGKAF 398
Cdd:COG5048   192 VSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllSQSPSSLSSSDSSSSASEsPRSSLPTASS 270

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 399 IWSSTLTRHKRMHTG-EKPYKCEECGKSFSQSSTLTTHK--IIHTGE--KPYKCEE--CGKAFNWSSTLTKHKIIHTEEK 471
Cdd:COG5048   271 QSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSIS 350

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 472 PYKC--EKCGKAFKQSSI-----LTNHKRIHTGEKPYKCE--ECGKSFNRSSTFTKHKVIHTGVKP--YKCEECGKAFFW 540
Cdd:COG5048   351 PAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNR 430

                         410
                  ....*....|..
gi 1034610226 541 SSTLTKHKRIHT 552
Cdd:COG5048   431 HYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
106-521 1.26e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 1.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 106 KKSFKCKKRVKLFCMLSHKTQHKSIYHREKSYKC--KECGKTFNWSSTLTNHRKIYTEEKPYKCEeyNKSPKQLSTLTTH 183
Cdd:COG5048    31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNS--KSLPLSNSKASSS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 184 EIIHAGEKLYKCE-ECGEAFNRSSNLTTHKIIHTGEKPYKCEECGKAFIWSSTLTEHKKIHTRKKPykcEECGKAFIWSS 262
Cdd:COG5048   109 SLSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSSNLS 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 263 TLTRHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTgEKRYKCLECGKAFKQLST----LTTHKIIHVGEKLYKCEEC 338
Cdd:COG5048   186 LLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLsqspSSLSSSDSSSSASESPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 339 G--KGFNRSSNLTTHKIIHTG-EKPYKCEECGKAFIWSSTLTKHKR--IHTRE--KPYKCEE--CGKAFIWSSTLTRHKR 409
Cdd:COG5048   265 LptASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHIL 344

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 410 MHTGEKPYKC--EECGKSFSQSST-----LTTHKIIHTGEKPYKCE--ECGKAFNWSSTLTKHKIIHTEEKPY--KCEKC 478
Cdd:COG5048   345 LHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYncKNPPC 424

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 1034610226 479 GKAFKQSSILTNHKRIHTGEKPYKCEECGKSFNRSSTFTKHKV 521
Cdd:COG5048   425 SKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGKD 467
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
149-536 3.70e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.41  E-value: 3.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 149 SSTLTNHRKIYTEEKPYKCEEYNKSPKQLSTLTTHEIIHAGEKLYKC--EECGEAFNRSSNLTTHKIIHTGEKPYKCE-E 225
Cdd:COG5048    18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 226 CGKAFIWSSTLTEHKKIHTRKKPYKCEECGKAFIWSSTLTRHKRMHTGEKPYKCEECGKAFSQSST-------------- 291
Cdd:COG5048    98 LPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQsnslhpplpansls 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 292 --------LTTHKIIHTGEKRYKCLECGKAFKQLSTLTTHKIIHVGEKLYKCEECG----KGFNRSSNLTTHKIIHTGEK 359
Cdd:COG5048   178 kdpssnlsLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSqlspKSLLSQSPSSLSSSDSSSSA 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 360 PYKCEECG--KAFIWSSTLTKHKRIHTR-EKPYKCEECGKAFIWSSTLTRHKRM--HTGE--KPYKCEE--CGKSFSQSS 430
Cdd:COG5048   258 SESPRSSLptASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRND 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 431 TLTTHKIIHTGEKPYKCEEC-------GKAFNWSSTLTKHKIIHTEEKPYKCE--KCGKAFKQSSILTNHKRIHTGEKPY 501
Cdd:COG5048   338 ALKRHILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPY 417

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 1034610226 502 --KCEECGKSFNRSSTFTKHKVIHTGVKPYKCEECGK 536
Cdd:COG5048   418 ncKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
246-577 1.20e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.86  E-value: 1.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 246 KKPYKCEECGKAFIWSSTLTRHKRMHTGEKPYKC--EECGKAFSQSSTLTTHKIIHTGEKRYkcLECGKAFKQLSTLTTH 323
Cdd:COG5048    31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 324 KIIHVGEKLYKCE-ECGKGFNRSSNLTTHKIIHTGEKPYKCEECGKAFIWSSTLTKHKRIHTREKPykcEECGKAFIWSS 402
Cdd:COG5048   109 SLSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSSNLS 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 403 TLTRHKRMHTGEKPYKCEECGKSFSQSSTLTTHKIIHTgEKPYKCEECGKAFN-----WSSTLTKHKIIHTEEKP-YKCE 476
Cdd:COG5048   186 LLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPksllsQSPSSLSSSDSSSSASEsPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 477 KCGKAFKQSSILTNHKRIHTG-EKPYKCEECGKSFNRSSTFTKHK--VIHTG--VKPYKCEE--CGKAFFWSSTLTKHKR 549
Cdd:COG5048   265 LPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGesLKPFSCPYslCGKLFSRNDALKRHIL 344

                         330       340       350
                  ....*....|....*....|....*....|....
gi 1034610226 550 IHTGEQPYKW------EKFGKAFNRSSHLTTDKI 577
Cdd:COG5048   345 LHTSISPAKEkllnssSKFSPLLNNEPPQSLQQY 378
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
219-571 2.44e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.63  E-value: 2.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 219 KPYKCEECGKAFIWSSTLTEHKKIHTRKKPYKC--EECGKAFIWSSTLTRHKRMHTGEKPYkcEECGKAFSQSSTLTTHK 296
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 297 IIHTGEKR-YKCLECGKAFKQLSTLTTHKIIHVGEKLYKCEECGKGFNRSSNLTTHKIIHTGEKPykcEECGKAFIWSST 375
Cdd:COG5048   110 LSSSSSNSnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 376 LTKHKRIHTREKPYKCEECGKAFIWSSTLTRHKRMHTgEKPYKCEECGKSFSQSSTLTTHKIIHTGEKPYKCEECGKAFN 455
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 456 WSSTLTKHKIIHTEE-------KPYKCEKCGKAFKQSSILTNHKR--IHTGE--KPYKCEE--CGKSFNRSSTFTKHKVI 522
Cdd:COG5048   266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1034610226 523 HTGVKPYKCeecgkafFWSSTLTKHKRIHTGE-----QPYKWEKFGKAFNRSSH 571
Cdd:COG5048   346 HTSISPAKE-------KLLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLSN 392
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 372-492 7.00e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 48.56  E-value: 7.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 372 WSSTLTKHKRIHTREKPYKCEECGKAFIWSSTL---TRHKRMHT-GEKPYKCE--ECGKSFSQSSTLTTHKiihtgekpy 445
Cdd:COG5189   301 IRGGISTGEMIDVRKLPCTNSSSNGKLAHGGERnidTPSRMLKVkDGKPYKCPveGCNKKYKNQNGLKYHM--------- 371

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1034610226 446 KCEECGKAFNWSSTLTKHKIIHTEEKPYKCEKCGKAFKQSSILTNHK 492
Cdd:COG5189   372 LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
404-428 1.44e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 1.44e-04
                          10        20
                  ....*....|....*....|....*
gi 1034610226 404 LTRHKRMHTGEKPYKCEECGKSFSQ 428
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
264-288 1.67e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 1.67e-04
                          10        20
                  ....*....|....*....|....*
gi 1034610226 264 LTRHKRMHTGEKPYKCEECGKAFSQ 288
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
488-512 5.36e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 5.36e-04
                          10        20
                  ....*....|....*....|....*
gi 1034610226 488 LTNHKRIHTGEKPYKCEECGKSFNR 512
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 232-352 1.09e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034610226 232 WSSTLTEHKKIHTRKKPYKCEECGKAFIWSSTL---TRHKRMHT-GEKPYKCE--ECGKAFSQSSTLTTHKIiHTgekry 305
Cdd:COG5189   301 IRGGISTGEMIDVRKLPCTNSSSNGKLAHGGERnidTPSRMLKVkDGKPYKCPveGCNKKYKNQNGLKYHML-HG----- 374

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1034610226 306 kclECGKAFKQLSTLTTHKIIHVGEKLYKCEECGKGFNRSSNLTTHK 352
Cdd:COG5189   375 ---HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
207-230 2.41e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.41e-03
                          10        20
                  ....*....|....*....|....
gi 1034610226 207 NLTTHKIIHTGEKPYKCEECGKAF 230
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
347-370 2.41e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.41e-03
                          10        20
                  ....*....|....*....|....
gi 1034610226 347 NLTTHKIIHTGEKPYKCEECGKAF 370
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
376-398 4.47e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 4.47e-03
                          10        20
                  ....*....|....*....|...
gi 1034610226 376 LTKHKRIHTREKPYKCEECGKAF 398
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
432-455 4.74e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.74e-03
                          10        20
                  ....*....|....*....|....
gi 1034610226 432 LTTHKIIHTGEKPYKCEECGKAFN 455
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
460-484 6.37e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 6.37e-03
                          10        20
                  ....*....|....*....|....*
gi 1034610226 460 LTKHKIIHTEEKPYKCEKCGKAFKQ 484
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH