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Conserved domains on  [gi|1121842482|ref|XP_019392728|]
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PREDICTED: gallinacin-13-like [Crocodylus porosus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BDD_Gal13 cd21908
beta-defensin domain found in gallinacin-13 (Gal-13); Gal-13, also called beta-defensin 13, ...
 27-61 2.43e-12

beta-defensin domain found in gallinacin-13 (Gal-13); Gal-13, also called beta-defensin 13, has bactericidal activity against Escherichia coli, Listeria monocytogenes, Salmonella typhimurium and Streptococcus pyogenes but not against Staphylococcus aureus. Gal-13 contains only one beta-defensin domain.


:

Pssm-ID: 439301  Cd Length: 35  Bit Score: 54.43  E-value: 2.43e-12
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 1121842482 27 STLQCRNNHGHCRRLCFHGEQWIGNCNGRHQHCCK 61
Cdd:cd21908    1 DSQQCRSNHGHCRRLCFHMERWEGSCSNGRLRCCR 35
 
Name Accession Description Interval E-value
BDD_Gal13 cd21908
beta-defensin domain found in gallinacin-13 (Gal-13); Gal-13, also called beta-defensin 13, ...
 27-61 2.43e-12

beta-defensin domain found in gallinacin-13 (Gal-13); Gal-13, also called beta-defensin 13, has bactericidal activity against Escherichia coli, Listeria monocytogenes, Salmonella typhimurium and Streptococcus pyogenes but not against Staphylococcus aureus. Gal-13 contains only one beta-defensin domain.


Pssm-ID: 439301  Cd Length: 35  Bit Score: 54.43  E-value: 2.43e-12
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 1121842482 27 STLQCRNNHGHCRRLCFHGEQWIGNCNGRHQHCCK 61
Cdd:cd21908    1 DSQQCRSNHGHCRRLCFHMERWEGSCSNGRLRCCR 35
Defensin_beta pfam00711
Beta defensin; The beta defensins are antimicrobial peptides implicated in the resistance of ...
 27-61 6.02e-05

Beta defensin; The beta defensins are antimicrobial peptides implicated in the resistance of epithelial surfaces to microbial colonization.


Pssm-ID: 459914  Cd Length: 36  Bit Score: 35.68  E-value: 6.02e-05
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 1121842482 27 STLQCRNNHGHCRRL-CFHGEQWIGNCNGRHQHCCK 61
Cdd:pfam00711  1 DPVSCRRNGGICRPGrCPGLERQIGTCGGGKLKCCR 36
 
Name Accession Description Interval E-value
BDD_Gal13 cd21908
beta-defensin domain found in gallinacin-13 (Gal-13); Gal-13, also called beta-defensin 13, ...
 27-61 2.43e-12

beta-defensin domain found in gallinacin-13 (Gal-13); Gal-13, also called beta-defensin 13, has bactericidal activity against Escherichia coli, Listeria monocytogenes, Salmonella typhimurium and Streptococcus pyogenes but not against Staphylococcus aureus. Gal-13 contains only one beta-defensin domain.


Pssm-ID: 439301  Cd Length: 35  Bit Score: 54.43  E-value: 2.43e-12
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 1121842482 27 STLQCRNNHGHCRRLCFHGEQWIGNCNGRHQHCCK 61
Cdd:cd21908    1 DSQQCRSNHGHCRRLCFHMERWEGSCSNGRLRCCR 35
Defensin_beta pfam00711
Beta defensin; The beta defensins are antimicrobial peptides implicated in the resistance of ...
 27-61 6.02e-05

Beta defensin; The beta defensins are antimicrobial peptides implicated in the resistance of epithelial surfaces to microbial colonization.


Pssm-ID: 459914  Cd Length: 36  Bit Score: 35.68  E-value: 6.02e-05
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 1121842482 27 STLQCRNNHGHCRRL-CFHGEQWIGNCNGRHQHCCK 61
Cdd:pfam00711  1 DPVSCRRNGGICRPGrCPGLERQIGTCGGGKLKCCR 36
BDD_Gal11-like cd21839
beta-defensin domain found in gallinacin-11 (Gal-11) and gallinacin-13 (Gal-13); The family ...
 31-60 8.98e-03

beta-defensin domain found in gallinacin-11 (Gal-11) and gallinacin-13 (Gal-13); The family includes the beta-defensin domains of gallinacin 11 (Gal-11) and Gal-13. Gal-11, also called beta-defensin 11, or vitelline membrane outer layer protein 2 or vitelline membrane outer layer protein II (VMO-II or VMOII), is an antimicrobial peptide found in chicken egg. It is one of four major proteins in vitelline membranes, along with ovomucin, lysozyme, and VMO-1. Gal-11 has bactericidal activity toward both Gram-positive and Gram-negative bacteria. It is a compact fold composed of 2 packed beta-defensin domains, with the beta-defensin#related motifs, CX6CX5CX9CX6CC and CX6CX6CX7CX6CC, respectively. Gal-13, also called beta-defensin 13, has bactericidal activity against Escherichia coli, Listeria monocytogenes, Salmonella typhimurium and Streptococcus pyogenes but not against Staphylococcus aureus. Gal-13 contains only one beta-defensin domain.


Pssm-ID: 439298  Cd Length: 32  Bit Score: 30.29  E-value: 8.98e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 1121842482 31 CRNNHGHCRRL--CFHGEQWIGNCNGRHQHCC 60
Cdd:cd21839    1 CQDKHGHCIRPkrCLEEFAAFGLCPLKRKTCC 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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