NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1143431107|ref|XP_019933944|]
View 

PREDICTED: anoctamin-5-like, partial [Paralichthys olivaceus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Anoctamin super family cl46385
Calcium-activated chloride channel; The family carries eight putative transmembrane domains, ...
 1-80 1.77e-19

Calcium-activated chloride channel; The family carries eight putative transmembrane domains, and, although it has no similarity to other known channel proteins, it is clearly a calcium-activated ionic channel. It is expressed in various secretory epithelia, the retina and sensory neurons, and mediates receptor-activated chloride currents in diverse physiological processes.


The actual alignment was detected with superfamily member pfam04547:

Pssm-ID: 480725  Cd Length: 377  Bit Score: 79.93  E-value: 1.77e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143431107   1 MGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQlqmRPEFEIRCtnRRLNKITQEMEPYLPITS-KCARFCLSTATVIF 79
Cdd:pfam04547  53 MSLWATLFLEFWKRREAELAYRWGTTGFEEEEEP---RPEFKGEK--ERINPVTGEKEPYYPPWKrRLRRYLLSIPLVLL 127


                  .
gi 1143431107  80 W 80
Cdd:pfam04547 128 L 128
 
Name Accession Description Interval E-value
Anoctamin pfam04547
Calcium-activated chloride channel; The family carries eight putative transmembrane domains, ...
 1-80 1.77e-19

Calcium-activated chloride channel; The family carries eight putative transmembrane domains, and, although it has no similarity to other known channel proteins, it is clearly a calcium-activated ionic channel. It is expressed in various secretory epithelia, the retina and sensory neurons, and mediates receptor-activated chloride currents in diverse physiological processes.


Pssm-ID: 461349  Cd Length: 377  Bit Score: 79.93  E-value: 1.77e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143431107   1 MGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQlqmRPEFEIRCtnRRLNKITQEMEPYLPITS-KCARFCLSTATVIF 79
Cdd:pfam04547  53 MSLWATLFLEFWKRREAELAYRWGTTGFEEEEEP---RPEFKGEK--ERINPVTGEKEPYYPPWKrRLRRYLLSIPLVLL 127


                  .
gi 1143431107  80 W 80
Cdd:pfam04547 128 L 128
 
Name Accession Description Interval E-value
Anoctamin pfam04547
Calcium-activated chloride channel; The family carries eight putative transmembrane domains, ...
 1-80 1.77e-19

Calcium-activated chloride channel; The family carries eight putative transmembrane domains, and, although it has no similarity to other known channel proteins, it is clearly a calcium-activated ionic channel. It is expressed in various secretory epithelia, the retina and sensory neurons, and mediates receptor-activated chloride currents in diverse physiological processes.


Pssm-ID: 461349  Cd Length: 377  Bit Score: 79.93  E-value: 1.77e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143431107   1 MGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQlqmRPEFEIRCtnRRLNKITQEMEPYLPITS-KCARFCLSTATVIF 79
Cdd:pfam04547  53 MSLWATLFLEFWKRREAELAYRWGTTGFEEEEEP---RPEFKGEK--ERINPVTGEKEPYYPPWKrRLRRYLLSIPLVLL 127


                  .
gi 1143431107  80 W 80
Cdd:pfam04547 128 L 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH