NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1720379716|ref|XP_030103703|]
View 

double homeobox B-like 1 isoform X1 [Mus musculus]

Protein Classification

homeodomain domain-containing protein( domain architecture ID 10815000)

homeodomain domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
95-149 1.75e-17

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 75.23  E-value: 1.75e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1720379716  95 RRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRARH 149
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKW 55
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 15-71 1.38e-13

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


:

Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 64.57  E-value: 1.38e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720379716  15 RRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTWFQKHR-KIRKQ 71
Cdd:cd00086     1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRaKLKRS 58
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
95-149 1.75e-17

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 75.23  E-value: 1.75e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1720379716  95 RRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRARH 149
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKW 55
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 95-149 5.94e-17

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 73.82  E-value: 5.94e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1720379716   95 RRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRARH 149
Cdd:smart00389   2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKW 56
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 95-149 6.40e-17

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 73.82  E-value: 6.40e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1720379716  95 RRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRARH 149
Cdd:cd00086     1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKL 55
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 15-71 1.38e-13

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 64.57  E-value: 1.38e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720379716  15 RRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTWFQKHR-KIRKQ 71
Cdd:cd00086     1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRaKLKRS 58
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 15-67 3.37e-13

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 63.42  E-value: 3.37e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720379716   15 RRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTWFQKHRK 67
Cdd:smart00389   2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRA 54
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
92-148 1.01e-12

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 65.15  E-value: 1.01e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720379716  92 KEARRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRAR 148
Cdd:COG5576    49 SPPKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAK 105
Homeodomain pfam00046
Homeodomain;
15-70 1.62e-12

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 61.75  E-value: 1.62e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720379716  15 RRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTWFQKHR-KIRK 70
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRaKWKR 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
11-92 4.44e-07

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 48.97  E-value: 4.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720379716  11 EKEARRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTWFQKHR-KIRKQAEFaccSEESQEQEQDKP 89
Cdd:COG5576    48 SSPPKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRaKEKKKRSG---KVEQRPGEEEAD 124


                  ...
gi 1720379716  90 RVK 92
Cdd:COG5576   125 LAK 127
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
95-149 1.75e-17

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 75.23  E-value: 1.75e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1720379716  95 RRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRARH 149
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKW 55
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 95-149 5.94e-17

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 73.82  E-value: 5.94e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1720379716   95 RRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRARH 149
Cdd:smart00389   2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKW 56
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 95-149 6.40e-17

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 73.82  E-value: 6.40e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1720379716  95 RRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRARH 149
Cdd:cd00086     1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKL 55
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 15-71 1.38e-13

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 64.57  E-value: 1.38e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720379716  15 RRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTWFQKHR-KIRKQ 71
Cdd:cd00086     1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRaKLKRS 58
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 15-67 3.37e-13

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 63.42  E-value: 3.37e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720379716   15 RRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTWFQKHRK 67
Cdd:smart00389   2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRA 54
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
92-148 1.01e-12

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 65.15  E-value: 1.01e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720379716  92 KEARRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRAR 148
Cdd:COG5576    49 SPPKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAK 105
Homeodomain pfam00046
Homeodomain;
15-70 1.62e-12

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 61.75  E-value: 1.62e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720379716  15 RRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTWFQKHR-KIRK 70
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRaKWKR 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
11-92 4.44e-07

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 48.97  E-value: 4.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720379716  11 EKEARRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTWFQKHR-KIRKQAEFaccSEESQEQEQDKP 89
Cdd:COG5576    48 SSPPKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRaKEKKKRSG---KVEQRPGEEEAD 124


                  ...
gi 1720379716  90 RVK 92
Cdd:COG5576   125 LAK 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH