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Conserved domains on  [gi|1838138447|ref|XP_033968144|]
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pericentrin isoform X1 [Pseudochaenichthys georgianus]

Protein Classification

SMC_prok_B and PACT_coil_coil domain-containing protein( domain architecture ID 13530588)

SMC_prok_B and PACT_coil_coil domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2419-3163 1.46e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 1.46e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2419 EDLNQRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQTASVdnkghrFQDLVLQVESLQAIIKDKTEDH 2498
Cdd:TIGR02168  196 NELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEE------LKEAEEELEELTAELQELEEKL 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2499 DSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALL----NDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSN 2574
Cdd:TIGR02168  270 EELRLEVSELEEEIEELQKELYALANEISRLEQQKQilreRLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2575 RLQISALQSKVDEtrhcyhdnQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTN 2654
Cdd:TIGR02168  350 KEELESLEAELEE--------LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2655 QNADHVNELQEQidalkenvsalailneereeqseaeepeEENFPSALIEEKNQEIDHLNAEIQRLEQELDNTEDNKA-L 2733
Cdd:TIGR02168  422 EIEELLKKLEEA----------------------------ELKELQAELEELEEELEELQEELERLEEALEELREELEeA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2734 EAELEDLRSQVEHLQSEVmRVRQDTQEEVERLHEVISTLQAELATLGPNLHEVSDS---QDGDSINPSPAPSPEPDNYTV 2810
Cdd:TIGR02168  474 EQALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2811 Q-EQARRGGANSLKQElslsysassHSLRSRFKTLQSqleAAAAEKEGLERLLLTQEEEYRGHGEEFgkrltaeREKADK 2889
Cdd:TIGR02168  553 EnLNAAKKAIAFLKQN---------ELGRVTFLPLDS---IKGTEIQGNDREILKNIEGFLGVAKDL-------VKFDPK 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2890 LQSVLTLKEAELDEVKAQKEGDAEERKLSEEVN------DKVQNQEMSTLRDKNLHLNSLiaevqkkeqERVTEMDTLKT 2963
Cdd:TIGR02168  614 LRKALSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgDLVRPGGVITGGSAKTNSSIL---------ERRREIEELEE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2964 KEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEAT 3043
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3044 SMRACIQELTVQLNEREASQEEAQKEVLTHAEvtlakadaALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKL 3123
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAEIEELEAQIEQLKE--------ELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 1838138447 3124 HEEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEELA 3163
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE 876
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3986-4063 4.63e-19

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


:

Pssm-ID: 463115  Cd Length: 77  Bit Score: 84.18  E-value: 4.63e-19
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1838138447 3986 RYLRAESFRKALVYQKRYLVLLLGGFQECEQATLCLIARMGAWPTPPLSSyNRPRSRFRAVVRVVIAVSRMKFLTKKW 4063
Cdd:pfam10495    1 KLLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS-RKPRRKLKSAALAVIAIARMKRLAREW 77
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1991-2781 7.82e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 7.82e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1991 KVQSEERLQDRINRLKTEFEEQKEARLEDLKRSFTSEQEEKErsytdkmsQLTIQLQQLDTVVAQLRAEVGCLQGELEGK 2070
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELE--------ELQEELKEAEEELEELTAELQELEEKLEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2071 RSEMETLDTLLQRRQRETQEGGNLLKMLTDDLQAGKEERRKLNQANEKLKKVLIEMIRstiatedmigQKICARAKTSEH 2150
Cdd:TIGR02168  273 RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES----------KLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2151 GSHQRSSTGNEDAQESGISVADMSSQDMELTHLLCESLL--VSDTQINPGGEEAALNAcsrlrhTVDTLLDLLNHANKQL 2228
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetLRSKVAQLELQIASLNN------EIERLEARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2229 EQTHGFHHSLEEKFSQGREDSAQllvqhkillEQLDQEAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERL 2308
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQ---------AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2309 VEELEDLKVKLHQMQGLTAELDGLRLKHQELSEEHSLLLRQKE-------HLSAGLGEREKALLAETERLTQDRLDLQRQ 2381
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyeaAIEAALGGRLQAVVVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2382 AEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLN-----------------------QRVQALEKQLKHDRQF 2438
Cdd:TIGR02168  568 NELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVkfdpklrkalsyllggvlvvddlDNALELAKKLRPGYRI 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2439 I--------------------EEQAVEREHERDEFQQEIRSLEAQLRQ-TASVDNKGHRFQDLVLQVESLQAIIKDKTED 2497
Cdd:TIGR02168  648 VtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAElEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2498 HDsliAANQQAQRDLAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQ 2577
Cdd:TIGR02168  728 IS---ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2578 ISALQSKVDETRHCYHDNQReptqelsdALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNA 2657
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2658 DHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEenfpsALIEEKNQEIDHLNAEIQRLEQELDNTednkaleaeL 2737
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELR-----RELEELREKLAQLELRLEGLEVRIDNL---------Q 942

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1838138447 2738 EDLRSQVEHLQSEVMRVRQDTQEEVERLHEVISTLQAELATLGP 2781
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1139-1728 2.13e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 2.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1139 RAAMEEEQAKDIQALRSQWDKNAESREsnlqmflsEMQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQTSSKDMN 1218
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELE--------ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1219 QElEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLES 1298
Cdd:COG1196    288 AE-EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1299 MRTSRQELGELKEQLLARSARVDDIERLKTEFNEQKREIKEQNEAELESLRRYFEQRLRATEEGHREEIALLQLRLVERA 1378
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1379 LEESVIRTADDSFSSISQGQAEEEKDHLFSDAVFKLEKHKEALDNVSLQLEEKHSMDLSYLQSSMSLSFKEELQQVQSDI 1458
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1459 TdqyyeELQELKTRHAMELEKLRAKLSDHHVKELTRAHLEAARQveveveqrmwcLTEELQSRMTIIhtLDSKLAALSKQ 1538
Cdd:COG1196    527 A-----VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY-----------LKAAKAGRATFL--PLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1539 HDAEVQRNTQKLKQEFAGELVHLEEALKQEREDVQEE-RKRWREELQEKHQAELSALRSELDREMESERTRLEKELHEEK 1617
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1618 ERLKTLQAALDNDESPQVLIVRQRLEAQYDGELQRAKSCMATEVKELTARLQEQGEERLHQAQERLHGEKAALEQSLAQK 1697
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1838138447 1698 YEASLAELKSKHQSELEHERAALLNKERDTL 1728
Cdd:COG1196    749 EEEALEELPEPPDLEELERELERLEREIEAL 779
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3510-3782 9.63e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 9.63e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3510 QLRAELEESQKQLKCAHDtqQEHKNKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERALSQRKDREKEERREALHVSS 3589
Cdd:COG1196    217 ELKEELKELEAELLLLKL--RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3590 EQQRSEVMALKGLVEQERvacSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKELKLqdktrLERLLAEAESR 3669
Cdd:COG1196    295 AELARLEQDIARLEERRR---ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE-----AEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3670 LAEIHSTLAEAHRKVDEERERYSRQVDELsRRHEADATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRsKWE 3749
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAA-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE-EAL 444

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1838138447 3750 EEDRARRAELQREKEAAIQQRVAVETLKEQKQE 3782
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 738-1339 1.28e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 1.28e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  738 QLEQLTNQ--NADHVNDLQEQIDALKAqcEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDR 815
Cdd:COG1196    201 QLEPLERQaeKAERYRELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  816 LQGELEKSLDSLDTAEQVKSELESQIFCLKQNLAKLEEAQAQTEQEREERRRKEEEMDDQIKKMEQVLEEELEQFESLLK 895
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  896 AKDVELSEAKEKweeesqeketellgVRHHLEEQRREREEEVKALLEKQVLAVEEETERLKTSHQQEIKDLMERHRQEIS 975
Cdd:COG1196    359 ELAEAEEALLEA--------------EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  976 ELNTHLESEQLKQqvnmEEEQKRQISFIKQVTEREHERMLSELSAKHNEELTQLRTEVSLELRESMEAAHQAELLQHQVQ 1055
Cdd:COG1196    425 ELEEALAELEEEE----EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1056 KRSELEAM--RLSLTNAHVSQLEQESALTEAQGSPRDTFAQEIALLKAQHQAELDHIRQQEKLRELQQQPMNDLQQQWET 1133
Cdd:COG1196    501 ADYEGFLEgvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1134 LVAQERAAMEEEQAKDIQALRSQWDKNAESRESNLQMFLSEM--QNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQ 1211
Cdd:COG1196    581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1212 TSSKDMNQELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQ 1291
Cdd:COG1196    661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1838138447 1292 LWtqlesmrtsrQELGELKEQLLARSARVDDIERLKTEFNEQKREIKE 1339
Cdd:COG1196    741 LL----------EEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 121-854 1.26e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 1.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  121 KEQLKQLQEAVEKRNEIIARLSSNLQEALASRDQVQLEAQSLAGQIQGLQRQLQQTSVEFLRIKSQ------------SG 188
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQkqilrerlanleRQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  189 AEVLNTRQPHGRCSQD---ADLNHKEAPSGSAAPETISCVEGFSTDTA----LEKLRVELEEERKNSQRIYAELALEMEK 261
Cdd:TIGR02168  318 LEELEAQLEELESKLDelaEELAELEEKLEELKEELESLEAELEELEAeleeLESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  262 HQHVLSLLEKEKNSREEEQKEKEEQLQDLQM-----QFSLVQTQCLEMQQYKEEKEKLNREVLELRKRLQEEADAERRLG 336
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEELLKkleeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  337 EEVASSALRLQRQEEEMLRLKEEHREEVEGVRQLLEEREKE----------LKFRE------EEVLGLKASK---NRQNK 397
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvlselISVDEgyeaaiEAALGGRLQAvvvENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  398 AKAGFSFDEKVNLD-----EAELETGPVENSMNVSVDILMERYMSSHRPAHSQSSVASDSLE-RCGQLDISADYsfelnS 471
Cdd:TIGR02168  558 AKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyLLGGVLVVDDL-----D 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  472 EVLGDEPLLSISNRFLEEDD---NRHNTSTPQCSPGiplpdNSNPQSPSQWLYDSTPD-ELETSKLSEQQFEQTDLEKEL 547
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDGdlvRPGGVITGGSAKT-----NSSILERRREIEELEEKiEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  548 --LNQQCGELRDELLLKDRDLNVLREEVINTAEELEEARSRWGQVTEELRQALWELEEEKEKKRLAEEEMNLKAHEQDNL 625
Cdd:TIGR02168  708 eeLEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  626 KSKLSALMEE--------REKEKAVLLTGKEAAETSL----LVPAITPSEEEDELVGELKKKKQQDLLLSQQEIKQPAIS 693
Cdd:TIGR02168  788 EAQIEQLKEElkalrealDELRAELTLLNEEAANLRErlesLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  694 AEQILELRDDKPLQTLQVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNDLQEQIDALKAQCEHLllhLEE 773
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL---QER 944

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  774 MTTTHKTTAALIDEKTTELDRTSKELERtraqvvnvqtEVDRLQGELEK----SLDSLDTAEQVK---SELESQIFCLKQ 846
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARR----------RLKRLENKIKElgpvNLAAIEEYEELKeryDFLTAQKEDLTE 1014


                   ....*...
gi 1838138447  847 NLAKLEEA 854
Cdd:TIGR02168 1015 AKETLEEA 1022
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3658-3952 1.11e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3658 RLERLLAEAESRLAEIHSTLAEAHRKVDE---ERERYSRQVDELSRRH---EADATRDRKFISDMRAQLEQERRQGEELA 3731
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEEleeELEQLRKELEELSRQIsalRKDLARLEAEVEQLEERIAQLSKELTELE 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3732 AVMNKLRAELLQSRSKwEEEDRARRAELQREKEAAIQQrvaVETLKEQKQETCCALEMERARSTQQGVELTELKEKLHLI 3811
Cdd:TIGR02168  761 AEIEELEERLEEAEEE-LAEAEAEIEELEAQIEQLKEE---LKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3812 KDKEREREEQweRERRKGRQEQMERERRQERT-----NDKLCELEMLRQQDQQRMQELQHTLVELEREEKEMSAQRLRQH 3886
Cdd:TIGR02168  837 ERRLEDLEEQ--IEELSEDIESLAAEIEELEElieelESELEALLNERASLEEALALLRSELEELSEELRELESKRSELR 914

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3887 NIAASSQHLQSDFQTGSAQHNQQMpssQNLLERMMKENS----ELTECVTSLSQEKATLKHRLTFLEREL 3952
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRI---DNLQERLSEEYSltleEAEALENKIEDDEEEARRRLKRLENKI 981
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2419-3163 1.46e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 1.46e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2419 EDLNQRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQTASVdnkghrFQDLVLQVESLQAIIKDKTEDH 2498
Cdd:TIGR02168  196 NELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEE------LKEAEEELEELTAELQELEEKL 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2499 DSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALL----NDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSN 2574
Cdd:TIGR02168  270 EELRLEVSELEEEIEELQKELYALANEISRLEQQKQilreRLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2575 RLQISALQSKVDEtrhcyhdnQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTN 2654
Cdd:TIGR02168  350 KEELESLEAELEE--------LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2655 QNADHVNELQEQidalkenvsalailneereeqseaeepeEENFPSALIEEKNQEIDHLNAEIQRLEQELDNTEDNKA-L 2733
Cdd:TIGR02168  422 EIEELLKKLEEA----------------------------ELKELQAELEELEEELEELQEELERLEEALEELREELEeA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2734 EAELEDLRSQVEHLQSEVmRVRQDTQEEVERLHEVISTLQAELATLGPNLHEVSDS---QDGDSINPSPAPSPEPDNYTV 2810
Cdd:TIGR02168  474 EQALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2811 Q-EQARRGGANSLKQElslsysassHSLRSRFKTLQSqleAAAAEKEGLERLLLTQEEEYRGHGEEFgkrltaeREKADK 2889
Cdd:TIGR02168  553 EnLNAAKKAIAFLKQN---------ELGRVTFLPLDS---IKGTEIQGNDREILKNIEGFLGVAKDL-------VKFDPK 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2890 LQSVLTLKEAELDEVKAQKEGDAEERKLSEEVN------DKVQNQEMSTLRDKNLHLNSLiaevqkkeqERVTEMDTLKT 2963
Cdd:TIGR02168  614 LRKALSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgDLVRPGGVITGGSAKTNSSIL---------ERRREIEELEE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2964 KEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEAT 3043
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3044 SMRACIQELTVQLNEREASQEEAQKEVLTHAEvtlakadaALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKL 3123
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAEIEELEAQIEQLKE--------ELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 1838138447 3124 HEEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEELA 3163
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE 876
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3986-4063 4.63e-19

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 84.18  E-value: 4.63e-19
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1838138447 3986 RYLRAESFRKALVYQKRYLVLLLGGFQECEQATLCLIARMGAWPTPPLSSyNRPRSRFRAVVRVVIAVSRMKFLTKKW 4063
Cdd:pfam10495    1 KLLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS-RKPRRKLKSAALAVIAIARMKRLAREW 77
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2359-3042 1.06e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.15  E-value: 1.06e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2359 EREKALLAETERltqdRLD-LQRQAEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLNQRVQALEKqlkhdrq 2437
Cdd:COG1196    189 ERLEDILGELER----QLEpLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEE------- 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2438 fIEEQAVEREHERDEFQQEIRSLEAQLRQtasvdnKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNE 2517
Cdd:COG1196    258 -LEAELAELEAELEELRLELEELELELEE------AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2518 EIDKLAGRIRELEQALLNDAEgkrSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRhcyhdNQR 2597
Cdd:COG1196    331 ELEELEEELEELEEELEEAEE---ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA-----AQL 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2598 EPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSAL 2677
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2678 AILNEEREEQSEAEEPEEENFPSALIEEKNQEIDHLNAEIQRLEQELdnTEDNKALEAELEDLRSQVehLQSEVMRVRQD 2757
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL--IGVEAAYEAALEAALAAA--LQNIVVEDDEV 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2758 TQEEVERLheviSTLQAELATLGPNlhevsdsqdgDSINPsPAPSPEPDNYTVQEQARRGGANSLKQELSLSYSASSHSl 2837
Cdd:COG1196    559 AAAAIEYL----KAAKAGRATFLPL----------DKIRA-RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL- 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2838 rsRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERKL 2917
Cdd:COG1196    623 --LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2918 SEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDME 2997
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 1838138447 2998 E---LVDEERikiKTLKTVKGELSAERETLRRREGKLQEEIENLRQEA 3042
Cdd:COG1196    781 PvnlLAIEEY---EELEERYDFLSEQREDLEEARETLEEAIEEIDRET 825
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1991-2781 7.82e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 7.82e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1991 KVQSEERLQDRINRLKTEFEEQKEARLEDLKRSFTSEQEEKErsytdkmsQLTIQLQQLDTVVAQLRAEVGCLQGELEGK 2070
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELE--------ELQEELKEAEEELEELTAELQELEEKLEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2071 RSEMETLDTLLQRRQRETQEGGNLLKMLTDDLQAGKEERRKLNQANEKLKKVLIEMIRstiatedmigQKICARAKTSEH 2150
Cdd:TIGR02168  273 RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES----------KLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2151 GSHQRSSTGNEDAQESGISVADMSSQDMELTHLLCESLL--VSDTQINPGGEEAALNAcsrlrhTVDTLLDLLNHANKQL 2228
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetLRSKVAQLELQIASLNN------EIERLEARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2229 EQTHGFHHSLEEKFSQGREDSAQllvqhkillEQLDQEAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERL 2308
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQ---------AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2309 VEELEDLKVKLHQMQGLTAELDGLRLKHQELSEEHSLLLRQKE-------HLSAGLGEREKALLAETERLTQDRLDLQRQ 2381
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyeaAIEAALGGRLQAVVVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2382 AEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLN-----------------------QRVQALEKQLKHDRQF 2438
Cdd:TIGR02168  568 NELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVkfdpklrkalsyllggvlvvddlDNALELAKKLRPGYRI 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2439 I--------------------EEQAVEREHERDEFQQEIRSLEAQLRQ-TASVDNKGHRFQDLVLQVESLQAIIKDKTED 2497
Cdd:TIGR02168  648 VtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAElEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2498 HDsliAANQQAQRDLAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQ 2577
Cdd:TIGR02168  728 IS---ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2578 ISALQSKVDETRHCYHDNQReptqelsdALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNA 2657
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2658 DHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEenfpsALIEEKNQEIDHLNAEIQRLEQELDNTednkaleaeL 2737
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELR-----RELEELREKLAQLELRLEGLEVRIDNL---------Q 942

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1838138447 2738 EDLRSQVEHLQSEVMRVRQDTQEEVERLHEVISTLQAELATLGP 2781
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1139-1728 2.13e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 2.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1139 RAAMEEEQAKDIQALRSQWDKNAESREsnlqmflsEMQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQTSSKDMN 1218
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELE--------ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1219 QElEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLES 1298
Cdd:COG1196    288 AE-EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1299 MRTSRQELGELKEQLLARSARVDDIERLKTEFNEQKREIKEQNEAELESLRRYFEQRLRATEEGHREEIALLQLRLVERA 1378
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1379 LEESVIRTADDSFSSISQGQAEEEKDHLFSDAVFKLEKHKEALDNVSLQLEEKHSMDLSYLQSSMSLSFKEELQQVQSDI 1458
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1459 TdqyyeELQELKTRHAMELEKLRAKLSDHHVKELTRAHLEAARQveveveqrmwcLTEELQSRMTIIhtLDSKLAALSKQ 1538
Cdd:COG1196    527 A-----VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY-----------LKAAKAGRATFL--PLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1539 HDAEVQRNTQKLKQEFAGELVHLEEALKQEREDVQEE-RKRWREELQEKHQAELSALRSELDREMESERTRLEKELHEEK 1617
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1618 ERLKTLQAALDNDESPQVLIVRQRLEAQYDGELQRAKSCMATEVKELTARLQEQGEERLHQAQERLHGEKAALEQSLAQK 1697
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1838138447 1698 YEASLAELKSKHQSELEHERAALLNKERDTL 1728
Cdd:COG1196    749 EEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3510-3782 9.63e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 9.63e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3510 QLRAELEESQKQLKCAHDtqQEHKNKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERALSQRKDREKEERREALHVSS 3589
Cdd:COG1196    217 ELKEELKELEAELLLLKL--RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3590 EQQRSEVMALKGLVEQERvacSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKELKLqdktrLERLLAEAESR 3669
Cdd:COG1196    295 AELARLEQDIARLEERRR---ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE-----AEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3670 LAEIHSTLAEAHRKVDEERERYSRQVDELsRRHEADATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRsKWE 3749
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAA-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE-EAL 444

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1838138447 3750 EEDRARRAELQREKEAAIQQRVAVETLKEQKQE 3782
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 738-1339 1.28e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 1.28e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  738 QLEQLTNQ--NADHVNDLQEQIDALKAqcEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDR 815
Cdd:COG1196    201 QLEPLERQaeKAERYRELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  816 LQGELEKSLDSLDTAEQVKSELESQIFCLKQNLAKLEEAQAQTEQEREERRRKEEEMDDQIKKMEQVLEEELEQFESLLK 895
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  896 AKDVELSEAKEKweeesqeketellgVRHHLEEQRREREEEVKALLEKQVLAVEEETERLKTSHQQEIKDLMERHRQEIS 975
Cdd:COG1196    359 ELAEAEEALLEA--------------EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  976 ELNTHLESEQLKQqvnmEEEQKRQISFIKQVTEREHERMLSELSAKHNEELTQLRTEVSLELRESMEAAHQAELLQHQVQ 1055
Cdd:COG1196    425 ELEEALAELEEEE----EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1056 KRSELEAM--RLSLTNAHVSQLEQESALTEAQGSPRDTFAQEIALLKAQHQAELDHIRQQEKLRELQQQPMNDLQQQWET 1133
Cdd:COG1196    501 ADYEGFLEgvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1134 LVAQERAAMEEEQAKDIQALRSQWDKNAESRESNLQMFLSEM--QNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQ 1211
Cdd:COG1196    581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1212 TSSKDMNQELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQ 1291
Cdd:COG1196    661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1838138447 1292 LWtqlesmrtsrQELGELKEQLLARSARVDDIERLKTEFNEQKREIKE 1339
Cdd:COG1196    741 LL----------EEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1036-1841 3.17e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 3.17e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1036 ELRESMEAAH-QAELLQHQVQKRSELEAMRLSLT----NAHVSQLEQESALTEAQGSPRDTFAQEIALLKAQHQAELDHI 1110
Cdd:TIGR02168  197 ELERQLKSLErQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1111 RQQEKLRELQQQPMNDLQQQWETLVAQERAAMEEEQAKDIQALRSQWD-KNAESRESNLQMFLSEMQNSLTATQTDLTQT 1189
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQlEELESKLDELAEELAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1190 LKALSQTQAELQRSGAKLQELQTSSKDMNQ---ELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQ 1266
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSkvaQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1267 LKQEVL-RLQEERSSLKKNSEQEVGQLWTQLESMRTSRQELGELKEQLLARSARVDDIERLKTEFNEQKREIKE--QNEA 1343
Cdd:TIGR02168  437 ELQAELeELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAllKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1344 ELESLRRYFEQRLRATEEghrEEIAllqlrlVERALEESVIRTADDSFSSISQGQAEEEKDHLFSDAVFKLEKHKEALDN 1423
Cdd:TIGR02168  517 GLSGILGVLSELISVDEG---YEAA------IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQ 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1424 VSlQLEEKHSMDLSYLQSSMSLSFKEELQQVQSDITDQYY--EELQE-LKTRHAMELEKLRAKLSDHHVKE---LTRAHl 1497
Cdd:TIGR02168  588 GN-DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvDDLDNaLELAKKLRPGYRIVTLDGDLVRPggvITGGS- 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1498 EAARQVEVEVEQRMWCLTEELQSRMTIIHTLDSKLAALSKQHDAEVQRNTQKLKQEFAgelvhLEEALKQEREDVQEERK 1577
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-----LSRQISALRKDLARLEA 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1578 RwrEELQEKHQAELSALRSELDREMESERTRLEKELHeekerlkTLQAALDNDESPQVLIVRQRLEAQYDGELQRAKScm 1657
Cdd:TIGR02168  741 E--VEQLEERIAQLSKELTELEAEIEELEERLEEAEE-------ELAEAEAEIEELEAQIEQLKEELKALREALDELR-- 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1658 aTEVKELTARLQEQgEERLHQAQERLHGEKAALEQSLAQKYEASLAELKSKHQSELEHERAALLNKERDTLDAKhKAQLD 1737
Cdd:TIGR02168  810 -AELTLLNEEAANL-RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE-RASLE 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1738 SLSASHRDQLTATAAELKsKHSAELVALEAALDSKRkadieslegvlKETNQAQLEASEAELTRKHQEEK-DELEMRMLG 1816
Cdd:TIGR02168  887 EALALLRSELEELSEELR-ELESKRSELRRELEELR-----------EKLAQLELRLEGLEVRIDNLQERlSEEYSLTLE 954

                          810       820
                   ....*....|....*....|....*
gi 1838138447 1817 NMDTLESTYLKEVQALRDEIIQLEE 1841
Cdd:TIGR02168  955 EAEALENKIEDDEEEARRRLKRLEN 979
PTZ00121 PTZ00121
MAEBL; Provisional
 1316-2045 8.44e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.55  E-value: 8.44e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1316 RSARVDDIERLKTEFNEQKREIKEQN---EAELESLRRYFEQRLRATEEGHREEIALLQLRLVERALEESVIRTADDSFS 1392
Cdd:PTZ00121  1062 AKAHVGQDEGLKPSYKDFDFDAKEDNradEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARK 1141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1393 SISQGQAEEEKDHLFSDAVFKLEKHKEALDNVSLQLEEKHSMDLSyLQSSMSLSFKEELQQVQSdiTDQYYEELQELKTR 1472
Cdd:PTZ00121  1142 AEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE-VRKAEELRKAEDARKAEA--ARKAEEERKAEEAR 1218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1473 HAMELEKLRAklsdhhVKELTRAHLEAARQVEVEVEQRMWCLTEELQSRMTIIHTLDSKLAALSKQHDAEVQRNTQKLKQ 1552
Cdd:PTZ00121  1219 KAEDAKKAEA------VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA 1292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1553 EfagELVHLEEALKQEREDVQEERKRWREELQEKHQaELSALRSELDREMESERTRLEKELHEEKERLKTLQAALDNDES 1632
Cdd:PTZ00121  1293 D---EAKKAEEKKKADEAKKKAEEAKKADEAKKKAE-EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA 1368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1633 PQvlivRQRLEAQYDGELQRAKScmatEVKELTARLQEQGEERLHQAQERlhgEKAALEQSLAQKYEASLAELKSKHQSE 1712
Cdd:PTZ00121  1369 AE----KKKEEAKKKADAAKKKA----EEKKKADEAKKKAEEDKKKADEL---KKAAAAKKKADEAKKKAEEKKKADEAK 1437

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1713 LEHERAALLNKERDTLDAKHKAQldslSASHRDQLTATAAELKSKHSAELVALEA---ALDSKRKADieSLEGVLKETNQ 1789
Cdd:PTZ00121  1438 KKAEEAKKADEAKKKAEEAKKAE----EAKKKAEEAKKADEAKKKAEEAKKADEAkkkAEEAKKKAD--EAKKAAEAKKK 1511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1790 AQlEASEAELTRKHQEEKDELEMRMLGNMDTLESTYLKEVQALRDEIIQLEERHCRGLNLQKSEHRQVLERHASEQLSIR 1869
Cdd:PTZ00121  1512 AD-EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1870 EELRKELAQLHIEKFSAMAVELShvhktelTAQKEALDTDHCKALETLKKQVLEVEQQHSLALQELSQTCTADKEQLLAQ 1949
Cdd:PTZ00121  1591 EARIEEVMKLYEEEKKMKAEEAK-------KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA 1663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1950 QQLQLQDLRgvSARELEACRRELEEESSRQRQHFLEEVELLKVQ----SEERLQDRINRLKTEfEEQKEARLEDLKRSFT 2025
Cdd:PTZ00121  1664 AEEAKKAEE--DKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelkkKEAEEKKKAEELKKA-EEENKIKAEEAKKEAE 1740

                          730       740
                   ....*....|....*....|
gi 1838138447 2026 SEQEEKERSYTDKMSQLTIQ 2045
Cdd:PTZ00121  1741 EDKKKAEEAKKDEEEKKKIA 1760
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1868-2466 1.19e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 1.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1868 IREELRKELAQLHI-----EKFSAMAVELSHVHKTELTAQKEALDTDhckaLETLKKQVLEVEQQHSLALQELSQTCTA- 1941
Cdd:COG1196    194 ILGELERQLEPLERqaekaERYRELKEELKELEAELLLLKLRELEAE----LEELEAELEELEAELEELEAELAELEAEl 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1942 DKEQLLAQQQLQLQDLRGVSARELEACRRELEEESSRQRqhfleevellkvQSEERLQDRINRLKTEfEEQKEARLEDLK 2021
Cdd:COG1196    270 EELRLELEELELELEEAQAEEYELLAELARLEQDIARLE------------ERRRELEERLEELEEE-LAELEEELEELE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2022 RsftsEQEEKERSYTDKMSQLTIQLQQLDTVVAQLRAEVGCLQGELEGKRSEMETLDTLLQRRQRETQEGGNLLKMLTDD 2101
Cdd:COG1196    337 E----ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2102 LQAGKEERRKLNQANEKLKKVLIEMIRSTIATEDMIGQKICARAKTSEHGSHQRSSTGNEDAQESGISVADMSSQDMELT 2181
Cdd:COG1196    413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2182 HLLCESLLVSDTQINPGGEEAALNACSRLRH-TVDTLLDLLNHANKQLEQTHG--FHHSLEEKFSQGREDSAQLLVQHKI 2258
Cdd:COG1196    493 LLLLLEAEADYEGFLEGVKAALLLAGLRGLAgAVAVLIGVEAAYEAALEAALAaaLQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2259 LLEQLDQEAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERLVEEL---EDLKVKLHQMQGLTAELDGLRLK 2335
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTlvaARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2336 HQELSEEHSLLLRQKEHLSAGLGEREKALLAETERLTQDRLDLQRQAEKDHKSLSLRLRALERDLEEKETQDLETEQhhk 2415
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ--- 729

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1838138447 2416 thNEDLNQRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQ 2466
Cdd:COG1196    730 --LEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 121-854 1.26e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 1.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  121 KEQLKQLQEAVEKRNEIIARLSSNLQEALASRDQVQLEAQSLAGQIQGLQRQLQQTSVEFLRIKSQ------------SG 188
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQkqilrerlanleRQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  189 AEVLNTRQPHGRCSQD---ADLNHKEAPSGSAAPETISCVEGFSTDTA----LEKLRVELEEERKNSQRIYAELALEMEK 261
Cdd:TIGR02168  318 LEELEAQLEELESKLDelaEELAELEEKLEELKEELESLEAELEELEAeleeLESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  262 HQHVLSLLEKEKNSREEEQKEKEEQLQDLQM-----QFSLVQTQCLEMQQYKEEKEKLNREVLELRKRLQEEADAERRLG 336
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEELLKkleeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  337 EEVASSALRLQRQEEEMLRLKEEHREEVEGVRQLLEEREKE----------LKFRE------EEVLGLKASK---NRQNK 397
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvlselISVDEgyeaaiEAALGGRLQAvvvENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  398 AKAGFSFDEKVNLD-----EAELETGPVENSMNVSVDILMERYMSSHRPAHSQSSVASDSLE-RCGQLDISADYsfelnS 471
Cdd:TIGR02168  558 AKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyLLGGVLVVDDL-----D 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  472 EVLGDEPLLSISNRFLEEDD---NRHNTSTPQCSPGiplpdNSNPQSPSQWLYDSTPD-ELETSKLSEQQFEQTDLEKEL 547
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDGdlvRPGGVITGGSAKT-----NSSILERRREIEELEEKiEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  548 --LNQQCGELRDELLLKDRDLNVLREEVINTAEELEEARSRWGQVTEELRQALWELEEEKEKKRLAEEEMNLKAHEQDNL 625
Cdd:TIGR02168  708 eeLEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  626 KSKLSALMEE--------REKEKAVLLTGKEAAETSL----LVPAITPSEEEDELVGELKKKKQQDLLLSQQEIKQPAIS 693
Cdd:TIGR02168  788 EAQIEQLKEElkalrealDELRAELTLLNEEAANLRErlesLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  694 AEQILELRDDKPLQTLQVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNDLQEQIDALKAQCEHLllhLEE 773
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL---QER 944

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  774 MTTTHKTTAALIDEKTTELDRTSKELERtraqvvnvqtEVDRLQGELEK----SLDSLDTAEQVK---SELESQIFCLKQ 846
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARR----------RLKRLENKIKElgpvNLAAIEEYEELKeryDFLTAQKEDLTE 1014


                   ....*...
gi 1838138447  847 NLAKLEEA 854
Cdd:TIGR02168 1015 AKETLEEA 1022
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2359-3162 1.90e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.14  E-value: 1.90e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2359 EREKALLAETERLTQdRLDLQRQAEKDHKSLSLRLRALERDLEEKETQDLETEqhhkthNEDLNQRVQALEKQLKHDRQF 2438
Cdd:pfam02463  173 EALKKLIEETENLAE-LIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE------YLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2439 IEEQAVEREHERDEFQQEIRSLEAQLRQTASVDNkghrfqdlvlQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEE 2518
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK----------EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEK 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2519 IDKLAGRIRELEQALLNDaegKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKvdetrhcyhdnQRE 2598
Cdd:pfam02463  316 LKESEKEKKKAEKELKKE---KEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAK-----------KKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2599 PTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALA 2678
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2679 ILNEEREEQSEAEEPEEenfpsaliEEKNQEIDHLNAEIQRLEQELDNTEDNKALEAELEDLRSQVEHLQSEVMRVRQDT 2758
Cdd:pfam02463  462 KDELELKKSEDLLKETQ--------LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGD 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2759 QEEVERLHEV--ISTLQAELATLGPNLHEVSDSQDGDSINPSPAPSPEPDNYTVQEQARRGGANSLKQELSLSYSASSHS 2836
Cdd:pfam02463  534 LGVAVENYKVaiSTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATL 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2837 LRSRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERK 2916
Cdd:pfam02463  614 EADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEE 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2917 LSEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDM 2996
Cdd:pfam02463  694 ILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKE 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2997 EELVDEERIKIKTLKTV-KGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEVLTHAE 3075
Cdd:pfam02463  774 KELAEEREKTEKLKVEEeKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3076 VTLAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDL 3155
Cdd:pfam02463  854 EELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKY 933


                   ....*..
gi 1838138447 3156 AVQEEEL 3162
Cdd:pfam02463  934 EEEPEEL 940
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2812-3161 7.60e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.90  E-value: 7.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2812 EQARRGGANSLKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEGLErlllTQEEEYRGHGEEFGKRLTAEREKADKLQ 2891
Cdd:PRK02224   179 ERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYE----EQREQARETRDEADEVLEEHEERREELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2892 SVltlkEAELDEVKAQKEGDAEERK-LSEEVNDkvQNQEMSTLRDKNLHLNS--------------LIAEVQKKEQERVT 2956
Cdd:PRK02224   255 TL----EAEIEDLRETIAETEREREeLAEEVRD--LRERLEELEEERDDLLAeaglddadaeaveaRREELEDRDEELRD 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2957 EMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREG------- 3029
Cdd:PRK02224   329 RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGdapvdlg 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3030 -------KLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQ-------KEVLTHAEvTLAKADAALRQREAELARL 3095
Cdd:PRK02224   409 naedfleELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpVEGSPHVE-TIEEDRERVEELEAELEDL 487

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1838138447 3096 RAEHQALKAELTEVKQgLSTSTERAEKLHEEGQTKDRALLNLET--DNQRLKAQ-LRALQEDLAVQEEE 3161
Cdd:PRK02224   488 EEEVEEVEERLERAED-LVEAEDRIERLEERREDLEELIAERREtiEEKRERAEeLRERAAELEAEAEE 555
PTZ00121 PTZ00121
MAEBL; Provisional
 3486-3885 1.75e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.84  E-value: 1.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3486 RPTQTDHRVEGDWHGDRVDGQVESQLRAELEESQKQLKCAHDTQQEHKNKMQSVRVA--VAEGEEALRREQVRVQELQQQ 3563
Cdd:PTZ00121  1218 RKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAeeARKADELKKAEEKKKADEAKK 1297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3564 LEQERALSQRKDREKEERR-EALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLD---------- 3632
Cdd:PTZ00121  1298 AEEKKKADEAKKKAEEAKKaDEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaekkkeeak 1377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3633 ---DTQKELGDERQLSANQKELKLQDKTRLERLL-AEAESRLAEIHSTLAEAHRKVDEERERY--SRQVDELSRRHEada 3706
Cdd:PTZ00121  1378 kkaDAAKKKAEEKKKADEAKKKAEEDKKKADELKkAAAAKKKADEAKKKAEEKKKADEAKKKAeeAKKADEAKKKAE--- 1454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3707 trDRKFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRSkweeEDRARRAELQREKEAAIQQRVAVETLKEQKQetccA 3786
Cdd:PTZ00121  1455 --EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA----EEAKKKADEAKKAAEAKKKADEAKKAEEAKK----A 1524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3787 LEMERARSTQQGVELTELKEklhliKDKEREREEQWERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQElqh 3866
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEE-----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEE--- 1596

                          410
                   ....*....|....*....
gi 1838138447 3867 tLVELEREEKEMSAQRLRQ 3885
Cdd:PTZ00121  1597 -VMKLYEEEKKMKAEEAKK 1614
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 535-1350 2.24e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 2.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  535 EQQFEQTDLEKELLNQQCGELRDELLLKDRDLNVLREEVINTAEELEEARSRWGQVTEELRQALWELEEEKEKKRLAEEE 614
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  615 MNLKAHEQDNLKSK---LSALMEEREKEKAVLLTGKEAAEtsllvpaitpsEEEDElvgelKKKKQQDLLLSQQEIKqpa 691
Cdd:TIGR02168  318 LEELEAQLEELESKldeLAEELAELEEKLEELKEELESLE-----------AELEE-----LEAELEELESRLEELE--- 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  692 isaEQILELRDDkplqtlqVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNADH--------VNDLQEQIDALKAQ 763
Cdd:TIGR02168  379 ---EQLETLRSK-------VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELlkkleeaeLKELQAELEELEEE 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  764 CEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQtevdRLQGELEKSLDSLDTAEQVKSELESQIFC 843
Cdd:TIGR02168  449 LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE----RLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  844 LKQNLAKLEEAQAQTEQEREERRRKEEEMDDQIKKMEQVLEEELEQFESLLKAKDVELSEAKEKWEEESQEKETELLGVR 923
Cdd:TIGR02168  525 LSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  924 HHLEEQRREREEEVKALLEkQVLAVEEETERL----KTSHQQEI----KDLMERH--------RQEISELNTHLESEQLK 987
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLG-GVLVVDDLDNALelakKLRPGYRIvtldGDLVRPGgvitggsaKTNSSILERRREIEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  988 QQVNMEEEQKRQISFIKQVTEREHERMLSELSAKhNEELTQLRTEVSLE----LRESMEAAHQAELLQHQVQKRSELEAM 1063
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQL-RKELEELSRQISALrkdlARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1064 RLSLTnahvSQLEQESALTEAQGSPRDTFAQEIALLKAQHQAEldhIRQQEKLRELQQQPMNDLQQQWETLVAQERAAme 1143
Cdd:TIGR02168  763 IEELE----ERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL---REALDELRAELTLLNEEAANLRERLESLERRI-- 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1144 EEQAKDIQALRSQWDKNAESRESnlqmfLSEMQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQtsskdmnQELEA 1223
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIES-----LAAEIEELEELIEELESELEALLNERASLEEALALLRSEL-------EELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1224 ELEQACADRDAAARSLEELMSSHKAV---LQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEvgqLWTQLESMR 1300
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLelrLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1301 TSRQELGELkeQLLArsarVDDIERLKTEFNEQKREIKEQNEAeLESLRR 1350
Cdd:TIGR02168  979 NKIKELGPV--NLAA----IEEYEELKERYDFLTAQKEDLTEA-KETLEE 1021
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 121-394 7.88e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 7.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  121 KEQLKQLQEAVEKRNEIIARLSSNLQEALASRDQVQLEAQSLAGQIQGLQRQLQQTSVEFLRIKSQSGAEVLNTRQphgR 200
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE---L 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  201 CSQDADLNHKEApsgsaapetiscvegfstdtALEKLRVELEEERKNSQRIYAELALEMEKHQHVLSLLEKEKNSREEEQ 280
Cdd:COG1196    315 EERLEELEEELA--------------------ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  281 KEKEEQLQDLQMQFSLVQTQCLEMQQYKEEKEKLNREVLELRKRLQEEADAERRLGEEVASSALRLQRQEEEMLRLKEEH 360
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1838138447  361 REEVEGVRQLLEEREKELKFREEEVLGLKASKNR 394
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAE 488
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3534-3810 8.86e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 8.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3534 NKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERalsqRKDREKEERREALHVSSEQQRSEVMALKGLVEQERVACSNL 3613
Cdd:TIGR02168  670 SSILERRREIEELEEKIEELEEKIAELEKALAELR----KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3614 RRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKElklqDKTRLERLLAEAESRLAEIHSTLAEAHRKVDEERERYSR 3693
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA----EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3694 QVDELsRRHEADATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAELlqsrskweEEDRARRAELQREKEAAIQQRVAV 3773
Cdd:TIGR02168  822 LRERL-ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI--------EELESELEALLNERASLEEALALL 892

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1838138447 3774 ETLKEQKQETCCALEMERARSTQQGVELTELKEKLHL 3810
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLEL 929
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1972-2677 6.02e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.92  E-value: 6.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1972 LEEESSRQR-QHFLEEVELLKVQSEERlqDRINRLKTEFEEQKEARLE---------DLKRSFTSEQEEKERSYTDKMSQ 2041
Cdd:pfam12128  214 PKSRLNRQQvEHWIRDIQAIAGIMKIR--PEFTKLQQEFNTLESAELRlshlhfgykSDETLIASRQEERQETSAELNQL 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2042 LTIQLQQLDTVVAQLRAEVGCLQGELEGKRSEMETLDTLLQRRQRETQEggnllkMLTDDLQAGKEERRKLNQANEKLKk 2121
Cdd:pfam12128  292 LRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIE------TAAADQEQLPSWQSELENLEERLK- 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2122 VLIEMIRSTIATEDMIGQKICARAKTSEHGSHQRSSTGNEdAQESGISVADMSSQDMEltHLLCESLLVSDTQINPGGEE 2201
Cdd:pfam12128  365 ALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIRE-ARDRQLAVAEDDLQALE--SELREQLEAGKLEFNEEEYR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2202 AALNA------CSRLRHTVDTLLDL------LNHANKQLEQTHGFHHSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKL 2269
Cdd:pfam12128  442 LKSRLgelklrLNQATATPELLLQLenfderIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSA 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2270 KSELQ----------LEYHKTEGLL----EGYVAEKALLEESLQQKEVQEERLVEELEDLKVKLH----QMQGLTAELDG 2331
Cdd:pfam12128  522 LDELElqlfpqagtlLHFLRKEAPDweqsIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDlkriDVPEWAASEEE 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2332 LRLKHQELSE----EHSLLLRQKEHLSAGLGEREKALLAET--------ERLTQDRLDLQRQAEKDHKSlslRLRALERD 2399
Cdd:pfam12128  602 LRERLDKAEEalqsAREKQAAAEEQLVQANGELEKASREETfartalknARLDLRRLFDEKQSEKDKKN---KALAERKD 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2400 LEEKETQDLETEQhhkthnedlnqrvQALEKQLKHDRQFIEEQAVEREHERDEFQQEIrsLEAQLRQTASVDnkghrfqd 2479
Cdd:pfam12128  679 SANERLNSLEAQL-------------KQLDKKHQAWLEEQKEQKREARTEKQAYWQVV--EGALDAQLALLK-------- 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2480 lvlqveslQAIIKDKTEDHDSLIAANQQAQRDLAECN---EEIDKLAGRIRELEQALLNDAEGKRSISQLEQEL-HRSKL 2555
Cdd:pfam12128  736 --------AAIAARRSGAKAELKALETWYKRDLASLGvdpDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYqETWLQ 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2556 REQELSQDKQALEQQQLSNRLQISALQSKVdETRHCYHDNQREptqELSDALDLAQQSLRSKEQEVEAVVGQLETLQSEL 2635
Cdd:pfam12128  808 RRPRLATQLSNIERAISELQQQLARLIADT-KLRRAKLEMERK---ASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQ 883

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1838138447 2636 GlkEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSAL 2677
Cdd:pfam12128  884 A--QGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADH 923
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3658-3952 1.11e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3658 RLERLLAEAESRLAEIHSTLAEAHRKVDE---ERERYSRQVDELSRRH---EADATRDRKFISDMRAQLEQERRQGEELA 3731
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEEleeELEQLRKELEELSRQIsalRKDLARLEAEVEQLEERIAQLSKELTELE 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3732 AVMNKLRAELLQSRSKwEEEDRARRAELQREKEAAIQQrvaVETLKEQKQETCCALEMERARSTQQGVELTELKEKLHLI 3811
Cdd:TIGR02168  761 AEIEELEERLEEAEEE-LAEAEAEIEELEAQIEQLKEE---LKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3812 KDKEREREEQweRERRKGRQEQMERERRQERT-----NDKLCELEMLRQQDQQRMQELQHTLVELEREEKEMSAQRLRQH 3886
Cdd:TIGR02168  837 ERRLEDLEEQ--IEELSEDIESLAAEIEELEElieelESELEALLNERASLEEALALLRSELEELSEELRELESKRSELR 914

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3887 NIAASSQHLQSDFQTGSAQHNQQMpssQNLLERMMKENS----ELTECVTSLSQEKATLKHRLTFLEREL 3952
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRI---DNLQERLSEEYSltleEAEALENKIEDDEEEARRRLKRLENKI 981
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1534-1801 3.48e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 50.22  E-value: 3.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1534 ALSKQHDAEVQRntQKLKQEFAGELVHLEEALKQ---------------EREDVQEERKRWREELQEKHQAeLSALRSEL 1598
Cdd:NF012221  1560 ALADKERAEADR--QRLEQEKQQQLAAISGSQSQlestdqnaletngqaQRDAILEESRAVTKELTTLAQG-LDALDSQA 1636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1599 DREMES-ERTRLEKELHEekerLKTLQAALDNDESpqvlIVRQRLEA---QYDGELQRAKSCMAtevKELTArlQEQGEE 1674
Cdd:NF012221  1637 TYAGESgDQWRNPFAGGL----LDRVQEQLDDAKK----ISGKQLADakqRHVDNQQKVKDAVA---KSEAG--VAQGEQ 1703

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1675 RLHQAQERLHGEKAALEQ----SLAQKYEASLAELK-----SKHQSELEHERAALLNKerdTLDAKHKAQLDSLSASHR- 1744
Cdd:NF012221  1704 NQANAEQDIDDAKADAEKrkddALAKQNEAQQAESDanaaaNDAQSRGEQDASAAENK---ANQAQADAKGAKQDESDKp 1780

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1838138447 1745 DQLTATAAELKSK-HSAELVALEAA---LDSKRKADIESLEGvLKETNQAQLEASEAELTR 1801
Cdd:NF012221  1781 NRQGAAGSGLSGKaYSVEGVAEPGShinPDSPAAADGRFSEG-LTEQEQEALEGATNAVNR 1840
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 534-1404 3.95e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.97  E-value: 3.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  534 SEQQFEQTDLEKELLNQQCGELRDELLLKDRDLNVLREEVINTAEELEEAR----------SRWGQVTEELRQALWELEE 603
Cdd:pfam02463  175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYllyldylklnEERIDLLQELLRDEQEEIE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  604 EKEKKRLAEEEMNLKAHEQDNLKSKLSALMEEREKEKAVLLTGKEAAETSLLVPAITPSEEEDELvgELKKKKQQDLLLS 683
Cdd:pfam02463  255 SSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKES--EKEKKKAEKELKK 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  684 QQEIkqpaISAEQILELRDDKPLQTLQVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNDLQEQIDALKAQ 763
Cdd:pfam02463  333 EKEE----IEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  764 CEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDRLQGELEKSLDSLDTAEQVKSELESQIFC 843
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  844 LKQNLAKLEEAQAQTEQEREERRRKEEEMD---DQIKKMEQVLEEELEQFESLLKAKDVELSEAKEKWEEESQEKETELL 920
Cdd:pfam02463  489 LLSRQKLEERSQKESKARSGLKVLLALIKDgvgGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVR 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  921 GVRHHLEEQRREREEEVKALLEKQVLAVEEETERLKTShqQEIKDLMERHRQEISELNTHLESEQLKQQVNMEEEQKRQI 1000
Cdd:pfam02463  569 ALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLA--QLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1001 SFIKQVTEREHERMLSELSAKHNEELTQLRTEVSLELRESMEAAHQAELLQHQVQKRSELEAMRLSLTNAHVSQLEQESA 1080
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1081 LTEAQGSPRDTFAQEIALLKAQHQAELDHIRQQEKLRELQQQPMNDLQQQWETLVAQERAAMEEEQAKDIQALRSQWDKN 1160
Cdd:pfam02463  727 VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1161 AESRESNLQMFLSEmQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQTSSKDMNQELEAELEQACADRDAAARSLE 1240
Cdd:pfam02463  807 EEELKEEAELLEEE-QLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLK 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1241 ELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLESMRTSRQELGELKEQLLARSARV 1320
Cdd:pfam02463  886 DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRL 965

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1321 DDIERLKTEFNEQKREIKEQNEAELESLRRYfEQRLRATEEGHREEIALLQLRLVERALEESVIRTADDSFSSISQ---G 1397
Cdd:pfam02463  966 LLAKEELGKVNLMAIEEFEEKEERYNKDELE-KERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLelgG 1044


                   ....*..
gi 1838138447 1398 QAEEEKD 1404
Cdd:pfam02463 1045 SAELRLE 1051
PTZ00121 PTZ00121
MAEBL; Provisional
 3449-4017 5.59e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 5.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3449 DRRDNPSSIPPMGWQQEKRALQETVVALRELLCRMAQRPTQtdhRVEGDWHGDRVDGQVESQLRAELEESQKQLKCAHDT 3528
Cdd:PTZ00121  1069 DEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETG---KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA 1145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3529 QQEHKNKMQSVRVAVAEG---EEALRREQVR-VQELQQQLEQERALSQRKDREKEERREALHVSSEQQRSEVMALKGLVE 3604
Cdd:PTZ00121  1146 RKAEDAKRVEIARKAEDArkaEEARKAEDAKkAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKK 1225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3605 QERVACSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKELKLQDKTRLERLLAEAESRLAEiHSTLAEAHRKV 3684
Cdd:PTZ00121  1226 AEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKA 1304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3685 DEERERY--SRQVDELSRRHE-----ADATRDR---KFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRSKWEEEDRA 3754
Cdd:PTZ00121  1305 DEAKKKAeeAKKADEAKKKAEeakkkADAAKKKaeeAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAK 1384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3755 RRAELQRE----KEAAIQQRVAVETLKEQKQETCCALEM----ERARSTQQGVELTELKEKLHLIKDKEREREEQWERER 3826
Cdd:PTZ00121  1385 KKAEEKKKadeaKKKAEEDKKKADELKKAAAAKKKADEAkkkaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3827 RKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQhtlvelEREEKEMSAQRLRQHNIAASSQHLQSDFQTGSAQH 3906
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAK------KAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE 1538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3907 NQQMPSSQNLLERMMKENSELTECVTSLSQEKATLKHRLTFLERELRLTENELAKVTTETENRPTKDVISNTKVQRLYER 3986
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1838138447 3987 YLRAESFRKALVYQKRYLVLLLGGFQECEQA 4017
Cdd:PTZ00121  1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKA 1649
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3713-4000 8.87e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 8.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3713 ISDMRAQLEQERRQGE------ELAAVMNKLRAELLQSRskweeeDRARRAELQREKEAAIQQRVAVETLKEQKQETCCA 3786
Cdd:COG1196    195 LGELERQLEPLERQAEkaeryrELKEELKELEAELLLLK------LRELEAELEELEAELEELEAELEELEAELAELEAE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3787 LEMERARSTQQGVELTELKEKLHLIKDKEREREEQWERERRKGRQEQMERERRQErtndklcELEMLRQQDQQRMQELQH 3866
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE-------ELAELEEELEELEEELEE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3867 TLVELEREEKEMSAQRLRQHNIAASSQHLQSDFQTGSAQHNQQmpssQNLLERMMKENSELTECVTSLSQEKATLKHRLT 3946
Cdd:COG1196    342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL----AEELLEALRAAAELAAQLEELEEAEEALLERLE 417

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1838138447 3947 FLERELRLTENELAKVTTETENRPTKDVISNTKVQRLYERYLRAESFRKALVYQ 4000
Cdd:COG1196    418 RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 3613-3971 1.44e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 1.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3613 LRRELQIEQSRSELLEKRLDDTQKELGDERQlsANQKELKLQDKTRLERLLAEAESRLAEI--HSTLAEAHRKVDEERER 3690
Cdd:pfam17380  271 LNQLLHIVQHQKAVSERQQQEKFEKMEQERL--RQEKEEKAREVERRRKLEEAEKARQAEMdrQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3691 YSRQVDELSRRHEADATRDRKFISDMRAQLEQERRQGEELAAvMNKLRAELLQSRS-KWEEEDRARRAELQREKEAAIQQ 3769
Cdd:pfam17380  349 ELERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQK-NERVRQELEAARKvKILEEERQRKIQQQKVEMEQIRA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3770 RvavetLKEQKQETCCALEMERARSTQQgVELTELKeklhlikdkerereeqwererrkgRQEQMERERRQERTNDKLCE 3849
Cdd:pfam17380  428 E-----QEEARQREVRRLEEERAREMER-VRLEEQE------------------------RQQQVERLRQQEEERKRKKL 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3850 LEMLRQQDQQRMQELQHTLVELEREEKEMSAqrLRQHNIAASSQHLQSDFQTGSAQHNQ-QMPSSQNLLERMMKENSELT 3928
Cdd:pfam17380  478 ELEKEKRDRKRAEEQRRKILEKELEERKQAM--IEEERKRKLLEKEMEERQKAIYEEERrREAEEERRKQQEMEERRRIQ 555

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1838138447 3929 ECVTSLSQEKATLKHRLTFLERELRLTENELAKVTTETENRPT 3971
Cdd:pfam17380  556 EQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEATTPIT 598
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 3552-3880 2.11e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 44.34  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3552 REQVRVQELQQQLEQERALSQRKDREKEERREALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQsrsELLEKRL 3631
Cdd:pfam17380  279 QHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERER---ELERIRQ 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3632 DDTQKELGDERQlsaNQKELKLQDKTRLERLLAEAESRLAEIHSTLaEAHRKVDEERERYSRQVDELSRRHEADATRDRK 3711
Cdd:pfam17380  356 EERKRELERIRQ---EEIAMEISRMRELERLQMERQQKNERVRQEL-EAARKVKILEEERQRKIQQQKVEMEQIRAEQEE 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3712 fisdmrAQLEQERRQGEELAAVMNKLRAELLQSRSKWE----EEDRARRAELQREKEAAIQQRVAVETLKEQKQETccal 3787
Cdd:pfam17380  432 ------ARQREVRRLEEERAREMERVRLEEQERQQQVErlrqQEEERKRKKLELEKEKRDRKRAEEQRRKILEKEL---- 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3788 eMERARSTQQGVELTELKEKLHLIKDKEREREEQWERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQHT 3867
Cdd:pfam17380  502 -EERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQ 580

                          330
                   ....*....|...
gi 1838138447 3868 LVELEREEKEMSA 3880
Cdd:pfam17380  581 IVESEKARAEYEA 593
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1038-1382 4.18e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 4.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1038 RESMEAAHQAELLQHQVQKRSELEAMRlsltnahvsQLEQESALTEAQGSPRDTFAQEIALLKAQHQAELDHIRQQEKLR 1117
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRR---------KLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1118 ELQQqpmndlqqqwetlVAQERAAMEEEQAKDIQALRSQWDKNAESRESNLQmflsemqnsltatqtdltqtlKALSQTQ 1197
Cdd:pfam17380  361 ELER-------------IRQEEIAMEISRMRELERLQMERQQKNERVRQELE---------------------AARKVKI 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1198 AELQRSGAKLQELQTSSKDMNQELEAELEQACADRDAAARSLEELMSSHkavlQEREQQALHLEEKEEQLKQEVLRLQEE 1277
Cdd:pfam17380  407 LEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEE----QERQQQVERLRQQEEERKRKKLELEKE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1278 RSSLKKNSEQEVGQLWTQLESMRTSRQElGELKEQLLARSARvddiERLKTEFNEQKREIKEQ---NEAELESLRRYFEQ 1354
Cdd:pfam17380  483 KRDRKRAEEQRRKILEKELEERKQAMIE-EERKRKLLEKEME----ERQKAIYEEERRREAEEerrKQQEMEERRRIQEQ 557

                          330       340
                   ....*....|....*....|....*...
gi 1838138447 1355 RLRATEEGHREEiALLQLRLVERALEES 1382
Cdd:pfam17380  558 MRKATEERSRLE-AMEREREMMRQIVES 584
PTZ00121 PTZ00121
MAEBL; Provisional
 5-400 4.89e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 4.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447    5 ERQRKLETGRaKKASEMPRSQSLASYRQKREKGNSAGTSKKTQKRKGQTVSQndgATQGRPVDAALSSANDTELNKKTNH 84
Cdd:PTZ00121  1299 EEKKKADEAK-KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAK---AEAEAAADEAEAAEEKAEAAEKKKE 1374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447   85 EEPQKPEKSKVQPPALEQSPSPVEDIEEEELIA--LTGKEQLKQLQEAVEKRNEIIARLSSNLQEALASR--DQVQLEAQ 160
Cdd:PTZ00121  1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKKKAdeLKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKkaDEAKKKAE 1454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  161 SLAGQIQGLQRQLQQTSVEFLRIKSQSGAEVLNTRQPHGRCSQDADLNHKEAPSGSAAPETISCVEGFSTDTALEKLRVE 240
Cdd:PTZ00121  1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK 1534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  241 LEEERKNSQRIyaELALEMEKHQHVLSLLEKEK-NSREEEQKEKEEQLQDLQMQFSLVQTQCLEMQQYKEEKEKLNREvl 319
Cdd:PTZ00121  1535 KADEAKKAEEK--KKADELKKAEELKKAEEKKKaEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE-- 1610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  320 ELRKRLQEEADAER-RLGEEVASSALRLQRQEEEMLRLKEEHR--EEVEGVRQLLEEREKELKFREEEVLGlKASKNRQN 396
Cdd:PTZ00121  1611 EAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKkaEEENKIKAAEEAKKAEEDKKKAEEAK-KAEEDEKK 1689


                   ....
gi 1838138447  397 KAKA 400
Cdd:PTZ00121  1690 AAEA 1693
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2419-3163 1.46e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 1.46e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2419 EDLNQRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQTASVdnkghrFQDLVLQVESLQAIIKDKTEDH 2498
Cdd:TIGR02168  196 NELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEE------LKEAEEELEELTAELQELEEKL 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2499 DSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALL----NDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSN 2574
Cdd:TIGR02168  270 EELRLEVSELEEEIEELQKELYALANEISRLEQQKQilreRLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2575 RLQISALQSKVDEtrhcyhdnQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTN 2654
Cdd:TIGR02168  350 KEELESLEAELEE--------LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2655 QNADHVNELQEQidalkenvsalailneereeqseaeepeEENFPSALIEEKNQEIDHLNAEIQRLEQELDNTEDNKA-L 2733
Cdd:TIGR02168  422 EIEELLKKLEEA----------------------------ELKELQAELEELEEELEELQEELERLEEALEELREELEeA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2734 EAELEDLRSQVEHLQSEVmRVRQDTQEEVERLHEVISTLQAELATLGPNLHEVSDS---QDGDSINPSPAPSPEPDNYTV 2810
Cdd:TIGR02168  474 EQALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAALGGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2811 Q-EQARRGGANSLKQElslsysassHSLRSRFKTLQSqleAAAAEKEGLERLLLTQEEEYRGHGEEFgkrltaeREKADK 2889
Cdd:TIGR02168  553 EnLNAAKKAIAFLKQN---------ELGRVTFLPLDS---IKGTEIQGNDREILKNIEGFLGVAKDL-------VKFDPK 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2890 LQSVLTLKEAELDEVKAQKEGDAEERKLSEEVN------DKVQNQEMSTLRDKNLHLNSLiaevqkkeqERVTEMDTLKT 2963
Cdd:TIGR02168  614 LRKALSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgDLVRPGGVITGGSAKTNSSIL---------ERRREIEELEE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2964 KEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEAT 3043
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3044 SMRACIQELTVQLNEREASQEEAQKEVLTHAEvtlakadaALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKL 3123
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAEIEELEAQIEQLKE--------ELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 1838138447 3124 HEEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEELA 3163
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE 876
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3986-4063 4.63e-19

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 84.18  E-value: 4.63e-19
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1838138447 3986 RYLRAESFRKALVYQKRYLVLLLGGFQECEQATLCLIARMGAWPTPPLSSyNRPRSRFRAVVRVVIAVSRMKFLTKKW 4063
Cdd:pfam10495    1 KLLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS-RKPRRKLKSAALAVIAIARMKRLAREW 77
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2299-3121 3.57e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 3.57e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2299 QQKEVQEERLVEELEDLKvklhQMQGLTAELDGL--RLKHQ-ELSEEHSLLLRQKEHLSAGL-GEREKALLAETERLTQD 2374
Cdd:TIGR02168  172 ERRKETERKLERTRENLD----RLEDILNELERQlkSLERQaEKAERYKELKAELRELELALlVLRLEELREELEELQEE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2375 RLDLQRQaekdHKSLSLRLRALERDLEEKETQD--LETEQHHKTHN-EDLNQRVQALEKQLKHDRQfieeqaverehERD 2451
Cdd:TIGR02168  248 LKEAEEE----LEELTAELQELEEKLEELRLEVseLEEEIEELQKElYALANEISRLEQQKQILRE-----------RLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2452 EFQQEIRSLEAQLRQTAS-VDNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRIRELE 2530
Cdd:TIGR02168  313 NLERQLEELEAQLEELESkLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2531 QAL-LNDAEgkrsISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQisALQSKVDETRHCYHDNQ------REPTQEL 2603
Cdd:TIGR02168  393 LQIaSLNNE----IERLEARLERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQeelerlEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2604 SDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLAlQLEQLTNQNADHVNELQEQIDALKENVSALAILnee 2683
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-ALLKNQSGLSGILGVLSELISVDEGYEAAIEAA--- 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2684 reEQSEAEEPEEENFPSALieeknQEIDHL--NAEIQRLEQELDNTEDNKALEAELEDLRSQVEHLQSEVMRVRQDTQEE 2761
Cdd:TIGR02168  543 --LGGRLQAVVVENLNAAK-----KAIAFLkqNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2762 V------ERLHeVISTLQAELATLGPNLHEVSD-SQDGDSINPSPAPSPEPDNYTVQEQARRGGANSLKQELSLSYSASS 2834
Cdd:TIGR02168  616 KalsyllGGVL-VVDDLDNALELAKKLRPGYRIvTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2835 HSL------RSRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKRltaeREKADKLQSVLTLKEAELDEVKAQK 2908
Cdd:TIGR02168  695 ELEkalaelRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQLSKELTELEAEIEELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2909 EGDAEERKLSEEVNDKVQnQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQE 2988
Cdd:TIGR02168  771 EEAEEELAEAEAEIEELE-AQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2989 MRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQK 3068
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL 929

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1838138447 3069 EVlthaevtlakadAALRQREAEL-ARLRAEHQALKAELTEVKQGLSTSTERAE 3121
Cdd:TIGR02168  930 RL------------EGLEVRIDNLqERLSEEYSLTLEEAEALENKIEDDEEEAR 971
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2359-3042 1.06e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.15  E-value: 1.06e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2359 EREKALLAETERltqdRLD-LQRQAEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLNQRVQALEKqlkhdrq 2437
Cdd:COG1196    189 ERLEDILGELER----QLEpLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEE------- 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2438 fIEEQAVEREHERDEFQQEIRSLEAQLRQtasvdnKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNE 2517
Cdd:COG1196    258 -LEAELAELEAELEELRLELEELELELEE------AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2518 EIDKLAGRIRELEQALLNDAEgkrSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRhcyhdNQR 2597
Cdd:COG1196    331 ELEELEEELEELEEELEEAEE---ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA-----AQL 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2598 EPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSAL 2677
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2678 AILNEEREEQSEAEEPEEENFPSALIEEKNQEIDHLNAEIQRLEQELdnTEDNKALEAELEDLRSQVehLQSEVMRVRQD 2757
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL--IGVEAAYEAALEAALAAA--LQNIVVEDDEV 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2758 TQEEVERLheviSTLQAELATLGPNlhevsdsqdgDSINPsPAPSPEPDNYTVQEQARRGGANSLKQELSLSYSASSHSl 2837
Cdd:COG1196    559 AAAAIEYL----KAAKAGRATFLPL----------DKIRA-RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL- 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2838 rsRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERKL 2917
Cdd:COG1196    623 --LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2918 SEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDME 2997
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 1838138447 2998 E---LVDEERikiKTLKTVKGELSAERETLRRREGKLQEEIENLRQEA 3042
Cdd:COG1196    781 PvnlLAIEEY---EELEERYDFLSEQREDLEEARETLEEAIEEIDRET 825
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2221-2781 3.96e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 3.96e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2221 LNHANKQLEQTHGFHHSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQ 2300
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2301 KEVQEERLVEELEDLKVKLhqmQGLTAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGEREKALLAETERLTQDRLDLQR 2380
Cdd:COG1196    314 LEERLEELEEELAELEEEL---EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2381 QAEKdhkslSLRLRALERDLEEKETQDLETEQHHKTHNEDLNQRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSL 2460
Cdd:COG1196    391 ALRA-----AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2461 EAQLRQTASVDNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAA--NQQAQRDLAECNEEIDKLAGRIRELEQALLNDAE 2538
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2539 GKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHCYHDNQREPTQELSDALDLAQQSLRSKE 2618
Cdd:COG1196    546 AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2619 QEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEENF 2698
Cdd:COG1196    626 TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2699 PSALIEEKNQEIDHLNAEIQRLEQELDNTEDNKALEAELEDLRSQVEHLQSEVMRVRQDTQEEVERlhevistLQAELAT 2778
Cdd:COG1196    706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER-------LEREIEA 778


                   ...
gi 1838138447 2779 LGP 2781
Cdd:COG1196    779 LGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1991-2781 7.82e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 7.82e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1991 KVQSEERLQDRINRLKTEFEEQKEARLEDLKRSFTSEQEEKErsytdkmsQLTIQLQQLDTVVAQLRAEVGCLQGELEGK 2070
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELE--------ELQEELKEAEEELEELTAELQELEEKLEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2071 RSEMETLDTLLQRRQRETQEGGNLLKMLTDDLQAGKEERRKLNQANEKLKKVLIEMIRstiatedmigQKICARAKTSEH 2150
Cdd:TIGR02168  273 RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES----------KLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2151 GSHQRSSTGNEDAQESGISVADMSSQDMELTHLLCESLL--VSDTQINPGGEEAALNAcsrlrhTVDTLLDLLNHANKQL 2228
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetLRSKVAQLELQIASLNN------EIERLEARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2229 EQTHGFHHSLEEKFSQGREDSAQllvqhkillEQLDQEAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERL 2308
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQ---------AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2309 VEELEDLKVKLHQMQGLTAELDGLRLKHQELSEEHSLLLRQKE-------HLSAGLGEREKALLAETERLTQDRLDLQRQ 2381
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyeaAIEAALGGRLQAVVVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2382 AEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLN-----------------------QRVQALEKQLKHDRQF 2438
Cdd:TIGR02168  568 NELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVkfdpklrkalsyllggvlvvddlDNALELAKKLRPGYRI 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2439 I--------------------EEQAVEREHERDEFQQEIRSLEAQLRQ-TASVDNKGHRFQDLVLQVESLQAIIKDKTED 2497
Cdd:TIGR02168  648 VtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAElEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2498 HDsliAANQQAQRDLAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQ 2577
Cdd:TIGR02168  728 IS---ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2578 ISALQSKVDETRHCYHDNQReptqelsdALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNA 2657
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2658 DHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEenfpsALIEEKNQEIDHLNAEIQRLEQELDNTednkaleaeL 2737
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELR-----RELEELREKLAQLELRLEGLEVRIDNL---------Q 942

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1838138447 2738 EDLRSQVEHLQSEVMRVRQDTQEEVERLHEVISTLQAELATLGP 2781
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2308-2923 3.50e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 3.50e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2308 LVEELEDLKVKLhqmqgLTAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGEREKALlaETERLTQDRLDLQRQAekdhk 2387
Cdd:COG1196    218 LKEELKELEAEL-----LLLKLRELEAELEELEAELEELEAELEELEAELAELEAEL--EELRLELEELELELEE----- 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2388 slslrLRALERDLEEKETQDLETEQHHKTHNEDLNQRVQALEKQLKHdrqfIEEQAVEREHERDEFQQEIRSLEAQLRQT 2467
Cdd:COG1196    286 -----AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE----LEEELEELEEELEELEEELEEAEEELEEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2468 AsvdnkghrfQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLE 2547
Cdd:COG1196    357 E---------AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2548 QELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHCYHDNQREpTQELSDALDLAQQSLRSKEQEVEAVVGQ 2627
Cdd:COG1196    428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA-LAELLEELAEAAARLLLLLEAEADYEGF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2628 LETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEENFPSALIEEKn 2707
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR- 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2708 qeidhlnaeiqrleqELDNTEDNKALEAELEDLRSQVEHLQSEVMRVRQDTQEEVERLHEVISTLQAELATLGPNLHEVS 2787
Cdd:COG1196    586 ---------------AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2788 DSQDGDSINPSpapspepdnytVQEQARRGGANSLKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEGLERLLLTQEE 2867
Cdd:COG1196    651 LEGEGGSAGGS-----------LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1838138447 2868 EYRGHGEEfgkrLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERKLSEEVND 2923
Cdd:COG1196    720 ELEEEALE----EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2374-3161 1.58e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.80  E-value: 1.58e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2374 DRLDLQRQAEKDHKSLSLRLRALERDLEEKETQDLETEQhhkthnEDLNQRVQALEKQLkhdrQFIEEQAVEREHERDEF 2453
Cdd:TIGR02169  201 ERLRREREKAERYQALLKEKREYEGYELLKEKEALERQK------EAIERQLASLEEEL----EKLTEEISELEKRLEEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2454 QQEIRSLEAQLRqtASVDNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIaanQQAQRDLAECNEEIDKLAGRIRELEQAL 2533
Cdd:TIGR02169  271 EQLLEELNKKIK--DLGEEEQLRVKEKIGELEAEIASLERSIAEKEREL---EDAEERLAKLEAEIDKLLAEIEELEREI 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2534 LNDAEGKRS----ISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHcYHDNQREPTQELSDALDL 2609
Cdd:TIGR02169  346 EEERKRRDKlteeYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR-ELDRLQEELQRLSEELAD 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2610 AQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALAILNEEREEQSE 2689
Cdd:TIGR02169  425 LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2690 AEEPEEENfpSALIEEKNQEIDHLNAEIQRLEQE------------LDN--TEDNKALEAELEDLRS------------- 2742
Cdd:TIGR02169  505 RVRGGRAV--EEVLKASIQGVHGTVAQLGSVGERyataievaagnrLNNvvVEDDAVAKEAIELLKRrkagratflplnk 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2743 -QVEHLQSEVMR-----------VRQDTQEE------------VERLHEVISTL-QAELATLGPNLHEVSDSQDGDSINP 2797
Cdd:TIGR02169  583 mRDERRDLSILSedgvigfavdlVEFDPKYEpafkyvfgdtlvVEDIEAARRLMgKYRMVTLEGELFEKSGAMTGGSRAP 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2798 SPAPSPEPDNYTVQEQARRgganslKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFG 2877
Cdd:TIGR02169  663 RGGILFSRSEPAELQRLRE------RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2878 KRLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEE-RKLSEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKEqERVT 2956
Cdd:TIGR02169  737 ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIE-ARLR 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2957 EMDTlktKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIE 3036
Cdd:TIGR02169  816 EIEQ---KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERD 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3037 NLRQEATSMRACIQELTVQLNEREASQEEaQKEVLTHAEVTLAKADAALRQREAELARLRAEHQaLKAELTEVKQGLSTS 3116
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSE-LKAKLEALEEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRAL 970

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 1838138447 3117 TERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEE 3161
Cdd:TIGR02169  971 EPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1139-1728 2.13e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 2.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1139 RAAMEEEQAKDIQALRSQWDKNAESREsnlqmflsEMQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQTSSKDMN 1218
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELE--------ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1219 QElEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLES 1298
Cdd:COG1196    288 AE-EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1299 MRTSRQELGELKEQLLARSARVDDIERLKTEFNEQKREIKEQNEAELESLRRYFEQRLRATEEGHREEIALLQLRLVERA 1378
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1379 LEESVIRTADDSFSSISQGQAEEEKDHLFSDAVFKLEKHKEALDNVSLQLEEKHSMDLSYLQSSMSLSFKEELQQVQSDI 1458
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1459 TdqyyeELQELKTRHAMELEKLRAKLSDHHVKELTRAHLEAARQveveveqrmwcLTEELQSRMTIIhtLDSKLAALSKQ 1538
Cdd:COG1196    527 A-----VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY-----------LKAAKAGRATFL--PLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1539 HDAEVQRNTQKLKQEFAGELVHLEEALKQEREDVQEE-RKRWREELQEKHQAELSALRSELDREMESERTRLEKELHEEK 1617
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1618 ERLKTLQAALDNDESPQVLIVRQRLEAQYDGELQRAKSCMATEVKELTARLQEQGEERLHQAQERLHGEKAALEQSLAQK 1697
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1838138447 1698 YEASLAELKSKHQSELEHERAALLNKERDTL 1728
Cdd:COG1196    749 EEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2209-2775 7.84e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 7.84e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2209 RLRHTVDTLLDLLNHANKQLEQTHGFHHSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKLKSELQLEYHKTEGLLEGYV 2288
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2289 AEKALLEESLQQKEVQEERLVEELEDLKVKLHQMQgltAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGEREKALLAET 2368
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAE---AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2369 ERLTQDRLDLQRQAEKDHKSLSLRLRALERDLEEKETQD--LETEQHHKTHNEDLNQRVQALEKQLKHDRQFIEEQAVER 2446
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEeeEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2447 EHERDEFQQEIRSLEAQLRQTASVDNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRI 2526
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2527 RELEQALLNDAEGKRSISQLEQELHRSKLREQELS-------------QDKQALEQQQLSNRLQISALQSKVDETRHCYH 2593
Cdd:COG1196    560 AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARgaigaavdlvasdLREADARYYVLGDTLLGRTLVAARLEAALRRA 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2594 DNQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKEN 2673
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2674 VSALAILNEEREEQSEAEEPEEENFPSALIEE------KNQEIDHLNAEIQRLEQELDNTED-NKALEAELEDLRSQVEH 2746
Cdd:COG1196    720 ELEEEALEEQLEAEREELLEELLEEEELLEEEaleelpEPPDLEELERELERLEREIEALGPvNLLAIEEYEELEERYDF 799

                          570       580
                   ....*....|....*....|....*....
gi 1838138447 2747 LQSEvmrvRQDTQEEVERLHEVISTLQAE 2775
Cdd:COG1196    800 LSEQ----REDLEEARETLEEAIEEIDRE 824
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1448-2023 8.24e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 8.24e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1448 KEELQQVQSDITDQYYEELQELKTRHAMELEKLRAKLSDHHVK-ELTRAHLEAARQVEVEVEQRMwcltEELQSRmtiIH 1526
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAElAELEAELEELRLELEELELEL----EEAQAE---EY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1527 TLDSKLAALSKQHDAEVQR--NTQKLKQEFAGELVHLEEALKQEREDVQEERKRwREELQEKHQAELSALRSELDREMES 1604
Cdd:COG1196    292 ELLAELARLEQDIARLEERrrELEERLEELEEELAELEEELEELEEELEELEEE-LEEAEEELEEAEAELAEAEEALLEA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1605 ERTRLEKELHEEKERLKTLQAALDNDESPQVLIVRQRLEAQYDGELQRAKSCMATEVKELTARLQEQGEERLHQAQER-L 1683
Cdd:COG1196    371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAeE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1684 HGEKAALEQSLAQKYEASLAELKSKHQSELEHERAALLNKERDTLDAKHKAQLDSLSASHRDQLTATAAELKSKHSAELV 1763
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1764 ALEAALDSKRKADIESLEGVLKETNQAQLEASEAELTRKHQEEKDELEMRMLGNMDTLESTYLKEVQALRDEIIQLEERH 1843
Cdd:COG1196    531 GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1844 CRGLNLQKSEHrQVLERHASEQLSIREELRKELAQLHIEKFSAMAVELSHVHKTELTAQKEALDTDHCKALETLKKQVLE 1923
Cdd:COG1196    611 ADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1924 VEQQHSLALQELSQTCTADKEQLLAQQQLQLQDLRGVSARELEACRRELEEESSRQRQHFLEEVE-LLKVQSEERLQDRI 2002
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEeLPEPPDLEELEREL 769

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1838138447 2003 NRLKT--------------EFEEQKE------ARLEDLKRS 2023
Cdd:COG1196    770 ERLEReiealgpvnllaieEYEELEErydflsEQREDLEEA 810
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2236-3081 1.16e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.71  E-value: 1.16e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2236 HSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERLVEELEDL 2315
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2316 KVKLhqmqgltaeldglrlkhQELSEEHSLLLRQKEHLSAGLGEREKALLaeterltqdrldlqrQAEKDHKSLSLRLRA 2395
Cdd:TIGR02168  315 ERQL-----------------EELEAQLEELESKLDELAEELAELEEKLE---------------ELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2396 LERDLEEKETQDLETEQHHKTHNEDLNQRVQALEkQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLrqtasvdnKGH 2475
Cdd:TIGR02168  363 LEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERLQQEIEELLKKL--------EEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2476 RFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALlndaEGKRSISQLEQELHRSkL 2555
Cdd:TIGR02168  434 ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL----DSLERLQENLEGFSEG-V 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2556 REQELSQDKQALEQQQLSNRLQI-------------SALQSKVDETrhcyhdnqreptqelSDALDLAQQSLRSKEQEVE 2622
Cdd:TIGR02168  509 KALLKNQSGLSGILGVLSELISVdegyeaaieaalgGRLQAVVVEN---------------LNAAKKAIAFLKQNELGRV 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2623 AVV-------GQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEE 2695
Cdd:TIGR02168  574 TFLpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGD 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2696 ENFPSALI----EEKNQEIDHLNAEIQRLEQELDNTE-DNKALEAELEDLRSQVEHLQSEVMRVRQDTQEEVERLHEVIS 2770
Cdd:TIGR02168  654 LVRPGGVItggsAKTNSSILERRREIEELEEKIEELEeKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2771 TLQAELATLGPNLHEVSDSQDGDSinpspapspEPDNYTVQEQARRGGANSLKQELSLSYsasshslrsrfKTLQSQLEA 2850
Cdd:TIGR02168  734 DLARLEAEVEQLEERIAQLSKELT---------ELEAEIEELEERLEEAEEELAEAEAEI-----------EELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2851 AAAEKEGLERLLLTQEEEYRGHGEEFGKRltaeREKADKLQSVLTLKEAELDEVKAQKEGDAEERKLSEEvndkvqnqEM 2930
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANL----RERLESLERRIAATERRLEDLEEQIEELSEDIESLAA--------EI 861

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2931 STLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTL 3010
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3011 K-TVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQEL-TVQLNEREASQEE--------AQKEVLTHAEVTLAK 3080
Cdd:TIGR02168  942 QeRLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgPVNLAAIEEYEELkerydfltAQKEDLTEAKETLEE 1021


                   .
gi 1838138447 3081 A 3081
Cdd:TIGR02168 1022 A 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2272-2816 1.28e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 1.28e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2272 ELQLEYHKTEGLLegYVAEKALLEESLQQKEVQEERLVEELEDLKVKLHQMQgltAELDGLRLKHQELSEEHSLLLRQKE 2351
Cdd:COG1196    217 ELKEELKELEAEL--LLLKLRELEAELEELEAELEELEAELEELEAELAELE---AELEELRLELEELELELEEAQAEEY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2352 HLSAGLGEREKALLAETERLTQDRLDLQRqAEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLNQRVQALEKQ 2431
Cdd:COG1196    292 ELLAELARLEQDIARLEERRRELEERLEE-LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2432 LKhdrqfiEEQAVEREHERDEfQQEIRSLEAQLRQTASVDNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRD 2511
Cdd:COG1196    371 EA------ELAEAEEELEELA-EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2512 LAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHC 2591
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2592 ------YHDNQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLET----------LQSELGLKEVELKHLALQLEQLTNQ 2655
Cdd:COG1196    524 gavavlIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflpLDKIRARAALAAALARGAIGAAVDL 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2656 NA----DHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEENFPSALIEEKNQEIDHLNAEIQRLEQELDNTEDNK 2731
Cdd:COG1196    604 VAsdlrEADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2732 ALEAELEDLRSQVEHLQSEVMRVRQDTQEEVERLHEVISTLQAELATLGPNLHEVSDSQDGDSINPSPAPSPEPDNYTVQ 2811
Cdd:COG1196    684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763


                   ....*
gi 1838138447 2812 EQARR 2816
Cdd:COG1196    764 ELERE 768
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2601-3162 1.59e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.59e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2601 QELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALAIL 2680
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2681 NEEREEQSEAEEPEEENfpsalIEEKNQEIDHLNAEIQRLEQELdntEDNKALEAELEDLRSQVEHLQSEVMRVRQDTQE 2760
Cdd:COG1196    308 EERRRELEERLEELEEE-----LAELEEELEELEEELEELEEEL---EEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2761 EVERLHEVISTLQAELATLGPNLHEVSDSQDGDsinpspapspepdnytVQEQARRGGANSLKQELSLSYSASSHSLRSR 2840
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEAL----------------LERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2841 FKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKRLTAEREKA---DKLQSVLTLKEAELDEVKAQKeGDAEERKL 2917
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAarlLLLLEAEADYEGFLEGVKAAL-LLAGLRGL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2918 SEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEmEMETEVLRETSLTLERQVQEMRAELVDME 2997
Cdd:COG1196    523 AGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG-RATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2998 ELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRAcIQELTVQLNEREASQEEAQKEVLTHAEVT 3077
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL-EGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3078 LAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDLAV 3157
Cdd:COG1196    681 LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760


                   ....*
gi 1838138447 3158 QEEEL 3162
Cdd:COG1196    761 DLEEL 765
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2525-3163 1.63e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.63e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2525 RIRELEQALLNDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQIsalqskvdetrhcyhdnqreptQELS 2604
Cdd:COG1196    223 KELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLEL----------------------EELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2605 DALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALAILNEer 2684
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA-- 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2685 eeqseaeepeeenfpsALIEEKNQEIDHLNAEIQRLEQELDNTEDNKALEAELEDLRSQVEHLQsevmRVRQDTQEEVER 2764
Cdd:COG1196    359 ----------------ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE----EAEEALLERLER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2765 LHEVISTLQAELATLGPNLHEVSDSQdgdsinpspapspepdnytvQEQARRGGANSLKQELSLSYSASSHSLRSRFKTL 2844
Cdd:COG1196    419 LEEELEELEEALAELEEEEEEEEEAL--------------------EEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2845 QSQLEAAAAEKEGLERLLLTQEEEYRGHGEefgkrlTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERKLSEEVNDK 2924
Cdd:COG1196    479 LAELLEELAEAAARLLLLLEAEADYEGFLE------GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2925 VQNQEmstlrdknlHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETE---VLRETSLTLERQVQEMRAELVDMEELVD 3001
Cdd:COG1196    553 VEDDE---------VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargAIGAAVDLVASDLREADARYYVLGDTLL 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3002 EERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEVLTHAEVTLAKA 3081
Cdd:COG1196    624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3082 DAALRQREAELARLRAEHQALKAEltevkqglststeraEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEE 3161
Cdd:COG1196    704 EEERELAEAEEERLEEELEEEALE---------------EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768


                   ..
gi 1838138447 3162 LA 3163
Cdd:COG1196    769 LE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1095-1670 2.16e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 2.16e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1095 EIALLKAQHQAELDHIRQQEKLRELQqqpmnDLQQQWETLVAQERAAmeEEQAKDIQALRSQWDKNAESRESNLQmflsE 1174
Cdd:COG1196    210 EKAERYRELKEELKELEAELLLLKLR-----ELEAELEELEAELEEL--EAELEELEAELAELEAELEELRLELE----E 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1175 MQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQTSskdmNQELEAELEQACADRDAAARSLEELMSSHKAVLQERE 1254
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEER----LEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1255 QQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLESMRTSRQELGELKEQLLARSARVDDIERLKTEFNEQK 1334
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1335 REIKEQNEAELESLRRyfEQRLRATEEGHREEIALLQLRLVERALEESVIRTADDSFSSISQGQAEEEKDHLFSDAVFKL 1414
Cdd:COG1196    435 EEEEEEEEALEEAAEE--EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1415 EKHKEALDNVSLQLEEKHSMDLSYlQSSMSLSFKEELQQVQSDITDQYYEELQELK-------TRHAMELEKLRAKLSDH 1487
Cdd:COG1196    513 ALLLAGLRGLAGAVAVLIGVEAAY-EAALEAALAAALQNIVVEDDEVAAAAIEYLKaakagraTFLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1488 HVKELTRAHLEAARQVEVEVEQRMWCLTEELQSRMTIIHTLDSKLAALSKQHDAEVQRNTQKLKQEFAGElvhLEEALKQ 1567
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS---LTGGSRR 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1568 EREDVQEERKRWREELQEKHQAELSALRSELDREMESERTRLEKELHEEKERLKTLQAALDNDESPQVLIVRQRLEAQYD 1647
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580
                   ....*....|....*....|...
gi 1838138447 1648 GELQRAKSCMATEVKELTARLQE 1670
Cdd:COG1196    749 EEEALEELPEPPDLEELERELER 771
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2840-3163 2.22e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 2.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2840 RFKTLQSQLEAAAAEKEGLERLLLTQEEEyrghgeEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEgdaeerklse 2919
Cdd:COG1196    214 RYRELKEELKELEAELLLLKLRELEAELE------ELEAELEELEAELEELEAELAELEAELEELRLELE---------- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2920 evndkVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEEL 2999
Cdd:COG1196    278 -----ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3000 VDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEVLTHAEvTLA 3079
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEE-ALA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3080 KADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRALlnletdnQRLKAQLRALQEDLAVQE 3159
Cdd:COG1196    432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL-------AEAAARLLLLLEAEADYE 504


                   ....
gi 1838138447 3160 EELA 3163
Cdd:COG1196    505 GFLE 508
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1524-2122 6.00e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 6.00e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1524 IIHTLDSKLAALSKQhdAEVQRNTQKLKQEF----AGELVHLEEALKQEREDVQEERKRwREELQEKHQAELSALRSELd 1599
Cdd:COG1196    194 ILGELERQLEPLERQ--AEKAERYRELKEELkeleAELLLLKLRELEAELEELEAELEE-LEAELEELEAELAELEAEL- 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1600 REMESERTRLEKELHEEKERLKTLQAALDNDEspQVLIVRQRLEAQYDGELQRAkscmATEVKELTARLQEQgEERLHQA 1679
Cdd:COG1196    270 EELRLELEELELELEEAQAEEYELLAELARLE--QDIARLEERRRELEERLEEL----EEELAELEEELEEL-EEELEEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1680 QERLHGEKAALEQSLAQkyEASLAELKSKHQSELEHERAALLNKERDTLDAKHKAQLDSLSASHRDQLTATAAELKSKHS 1759
Cdd:COG1196    343 EEELEEAEEELEEAEAE--LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1760 AELVALEAALDSKRKADIESLEGVLKE-TNQAQLEASEAELTRKHQEEKDELEmrmlgnmdtlesTYLKEVQALRDEIIQ 1838
Cdd:COG1196    421 EELEELEEALAELEEEEEEEEEALEEAaEEEAELEEEEEALLELLAELLEEAA------------LLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1839 LEERHCRGLNLQKSEHRQVLERHASEQLSIREELRKELAQLHIEKF--------SAMAVELSHVHKTELTAQK--EALDT 1908
Cdd:COG1196    489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAayeaaleaALAAALQNIVVEDDEVAAAaiEYLKA 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1909 DHCKALETLKKQVLEVEQQHSLALQELSQTCTADKEQLLAQQQLQLQDLRGVSARELEACRRELEEESSRQRQHFLEEVE 1988
Cdd:COG1196    569 AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1989 LLKVQSEERLQDRINRLKTEFEEQKEARLEDLKRSFTSEQEEKERSYTDKMSQLTIQLQQLDTVVAQLRAEVGCLQGELE 2068
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1838138447 2069 GKRSEMETLDTLLQRRQRETQEGGNLLKMLTDDLQAGKEERRKLNQANEKLKKV 2122
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPV 782
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2878-3163 7.67e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 7.67e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2878 KRLTAEREKADKLQSVLTLKEAELDEVKAQKEgDAEE-RKLSEEVndKVQNQEMSTLRDKNLHLNslIAEVQKKEQERVT 2956
Cdd:COG1196    179 RKLEATEENLERLEDILGELERQLEPLERQAE-KAERyRELKEEL--KELEAELLLLKLRELEAE--LEELEAELEELEA 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2957 EMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELV-------DMEELVDEERIKIKTLKTVKGELSAERETLRRREG 3029
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYellaelaRLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3030 KLQEEIENLRQEatsmracIQELTVQLNEREASQEEAQKEVLTHAEVTLAKADAALRQREAELARLRAEhQALKAELTEV 3109
Cdd:COG1196    334 ELEEELEELEEE-------LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA-AELAAQLEEL 405

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1838138447 3110 KQGLSTSTERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEELA 3163
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3510-3782 9.63e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 9.63e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3510 QLRAELEESQKQLKCAHDtqQEHKNKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERALSQRKDREKEERREALHVSS 3589
Cdd:COG1196    217 ELKEELKELEAELLLLKL--RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3590 EQQRSEVMALKGLVEQERvacSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKELKLqdktrLERLLAEAESR 3669
Cdd:COG1196    295 AELARLEQDIARLEERRR---ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE-----AEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3670 LAEIHSTLAEAHRKVDEERERYSRQVDELsRRHEADATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRsKWE 3749
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAA-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE-EAL 444

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1838138447 3750 EEDRARRAELQREKEAAIQQRVAVETLKEQKQE 3782
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 961-1578 1.05e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 1.05e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  961 QEIKDLMERHRQEISELN-THLESEQLKQQVNMEEEQKRQISFIKQVTEREHErmLSELSAKHNEELTQLRTEVSLELRE 1039
Cdd:COG1196    216 RELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAE--LEELRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1040 SMEAAHQAELLQHQVQKRSELEAMRLSLTNAHVSQLEQESALTEAqgspRDTFAQEIALLKAQHQAELDHIRQQEKLREL 1119
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE----LEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1120 QQQPMNDLQQQWETLVAQERAAMEE--EQAKDIQALRSQWDKNAESRESnlqmfLSEMQNSLTATQTDLTQTLKALSQTQ 1197
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAaaELAAQLEELEEAEEALLERLER-----LEEELEELEEALAELEEEEEEEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1198 AELQRSGAKLQELQTSSKDMNQELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALhleekeeqlkqevlRLQEE 1277
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG--------------FLEGV 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1278 RSSLKKNSEQEVGQLWTQLESMRTSRQELGELKEQLLARSARVDDIERLKtefnEQKREIKEQNEAELESLRRYFEQRLR 1357
Cdd:COG1196    511 KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAA----AAIEYLKAAKAGRATFLPLDKIRARA 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1358 ATEEGHREEIALLQLRLVERALEESVIRTADDSFSSISQGQAEEEKDHLFSDAVFKLEKHKEALDNVSLQLEEKHSMDLS 1437
Cdd:COG1196    587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1438 YLQSSMSLSFKEELQQVQSDITDQYYEELQELKtrhaMELEKLRAKLSDHHVKELTRAHLEAARQVEVEVEQRMwclTEE 1517
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEAL----LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE---LLE 739

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1838138447 1518 LQSRMTIIHTLDSKLAALSKQHDAEVQRNTQKLKQEFAG----------ELVHLEE---ALKQEREDVQEERKR 1578
Cdd:COG1196    740 ELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAlgpvnllaieEYEELEErydFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 738-1339 1.28e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 1.28e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  738 QLEQLTNQ--NADHVNDLQEQIDALKAqcEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDR 815
Cdd:COG1196    201 QLEPLERQaeKAERYRELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  816 LQGELEKSLDSLDTAEQVKSELESQIFCLKQNLAKLEEAQAQTEQEREERRRKEEEMDDQIKKMEQVLEEELEQFESLLK 895
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  896 AKDVELSEAKEKweeesqeketellgVRHHLEEQRREREEEVKALLEKQVLAVEEETERLKTSHQQEIKDLMERHRQEIS 975
Cdd:COG1196    359 ELAEAEEALLEA--------------EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  976 ELNTHLESEQLKQqvnmEEEQKRQISFIKQVTEREHERMLSELSAKHNEELTQLRTEVSLELRESMEAAHQAELLQHQVQ 1055
Cdd:COG1196    425 ELEEALAELEEEE----EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1056 KRSELEAM--RLSLTNAHVSQLEQESALTEAQGSPRDTFAQEIALLKAQHQAELDHIRQQEKLRELQQQPMNDLQQQWET 1133
Cdd:COG1196    501 ADYEGFLEgvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1134 LVAQERAAMEEEQAKDIQALRSQWDKNAESRESNLQMFLSEM--QNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQ 1211
Cdd:COG1196    581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1212 TSSKDMNQELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQ 1291
Cdd:COG1196    661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1838138447 1292 LWtqlesmrtsrQELGELKEQLLARSARVDDIERLKTEFNEQKREIKE 1339
Cdd:COG1196    741 LL----------EEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 795-1381 2.12e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 2.12e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  795 TSKELERTRAQVvnvqTEVDRLQGELEKSLDSL----DTAEQVKsELESQIFCLKQNLAKLEEAQAQTEQEREERRRKEE 870
Cdd:COG1196    177 AERKLEATEENL----ERLEDILGELERQLEPLerqaEKAERYR-ELKEELKELEAELLLLKLRELEAELEELEAELEEL 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  871 EMD-DQIKKMEQVLEEELEQFESLLKAKDVELSEAKEKWEEESQEKETELLGVRHHLEEQRREREEEVKALLEKQVLAVE 949
Cdd:COG1196    252 EAElEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEE 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  950 EETERLKTSHQQEIKDLMERHRQEISELNTHLESEQLKQQVNMEEEQKRQISFikqvtEREHERMLSELSAKHNEELTQL 1029
Cdd:COG1196    332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL-----AEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1030 RTEVSLELRESMEAAHQAELLQHQVQKRSELEAMRLSLTNAHVSQLEQESALTEAQgSPRDTFAQEIALLKAQHQAELDH 1109
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL-ELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1110 IRQQEKLRELQQQpmndLQQQWETLVAQERAAMEEEQAKDIQALRSQWDKNAESRESNLQMFLSE-MQNSLTATQTDLTQ 1188
Cdd:COG1196    486 LAEAAARLLLLLE----AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAaLQNIVVEDDEVAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1189 TLKALSQTQAElQRSGAKLQELQTSSKDMNQELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQLK 1268
Cdd:COG1196    562 AIEYLKAAKAG-RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1269 QEVLRLQEERSSLKKNSEQEVGQLWTQLESMRTSRQELGELKEQLLARSARVDDIERLKTEFNEQKREIKEQNEAELESL 1348
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                          570       580       590
                   ....*....|....*....|....*....|...
gi 1838138447 1349 RRYFEQRLRATEEGHREEIALLQLRLVERALEE 1381
Cdd:COG1196    721 LEEEALEEQLEAEREELLEELLEEEELLEEEAL 753
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2878-3162 2.46e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 2.46e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2878 KRLTAEREKADKLQSVLTLKE--------AELDEVKAQKEGDAEERKLSEEVNDKVQnQEMSTLRDKNLHLNSLIAEVQK 2949
Cdd:TIGR02169  201 ERLRREREKAERYQALLKEKReyegyellKEKEALERQKEAIERQLASLEEELEKLT-EEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2950 K-EQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRRE 3028
Cdd:TIGR02169  280 KiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEY 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3029 GKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEVLTHaEVTLAKADAALRQREAELARLRAEHQALKAELTE 3108
Cdd:TIGR02169  360 AELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINEL-KRELDRLQEELQRLSEELADLNAAIAGIEAKINE 438

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1838138447 3109 VKqglststERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEEL 3162
Cdd:TIGR02169  439 LE-------EEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL 485
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1036-1841 3.17e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 3.17e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1036 ELRESMEAAH-QAELLQHQVQKRSELEAMRLSLT----NAHVSQLEQESALTEAQGSPRDTFAQEIALLKAQHQAELDHI 1110
Cdd:TIGR02168  197 ELERQLKSLErQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1111 RQQEKLRELQQQPMNDLQQQWETLVAQERAAMEEEQAKDIQALRSQWD-KNAESRESNLQMFLSEMQNSLTATQTDLTQT 1189
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQlEELESKLDELAEELAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1190 LKALSQTQAELQRSGAKLQELQTSSKDMNQ---ELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQ 1266
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSkvaQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1267 LKQEVL-RLQEERSSLKKNSEQEVGQLWTQLESMRTSRQELGELKEQLLARSARVDDIERLKTEFNEQKREIKE--QNEA 1343
Cdd:TIGR02168  437 ELQAELeELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAllKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1344 ELESLRRYFEQRLRATEEghrEEIAllqlrlVERALEESVIRTADDSFSSISQGQAEEEKDHLFSDAVFKLEKHKEALDN 1423
Cdd:TIGR02168  517 GLSGILGVLSELISVDEG---YEAA------IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQ 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1424 VSlQLEEKHSMDLSYLQSSMSLSFKEELQQVQSDITDQYY--EELQE-LKTRHAMELEKLRAKLSDHHVKE---LTRAHl 1497
Cdd:TIGR02168  588 GN-DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvDDLDNaLELAKKLRPGYRIVTLDGDLVRPggvITGGS- 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1498 EAARQVEVEVEQRMWCLTEELQSRMTIIHTLDSKLAALSKQHDAEVQRNTQKLKQEFAgelvhLEEALKQEREDVQEERK 1577
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-----LSRQISALRKDLARLEA 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1578 RwrEELQEKHQAELSALRSELDREMESERTRLEKELHeekerlkTLQAALDNDESPQVLIVRQRLEAQYDGELQRAKScm 1657
Cdd:TIGR02168  741 E--VEQLEERIAQLSKELTELEAEIEELEERLEEAEE-------ELAEAEAEIEELEAQIEQLKEELKALREALDELR-- 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1658 aTEVKELTARLQEQgEERLHQAQERLHGEKAALEQSLAQKYEASLAELKSKHQSELEHERAALLNKERDTLDAKhKAQLD 1737
Cdd:TIGR02168  810 -AELTLLNEEAANL-RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE-RASLE 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1738 SLSASHRDQLTATAAELKsKHSAELVALEAALDSKRkadieslegvlKETNQAQLEASEAELTRKHQEEK-DELEMRMLG 1816
Cdd:TIGR02168  887 EALALLRSELEELSEELR-ELESKRSELRRELEELR-----------EKLAQLELRLEGLEVRIDNLQERlSEEYSLTLE 954

                          810       820
                   ....*....|....*....|....*
gi 1838138447 1817 NMDTLESTYLKEVQALRDEIIQLEE 1841
Cdd:TIGR02168  955 EAEALENKIEDDEEEARRRLKRLEN 979
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2812-3108 3.49e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 3.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2812 EQARRggANSLKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQ 2891
Cdd:COG1196    210 EKAER--YRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2892 SVLTLKEAELDEVKAQKEGDAEERKLSEEVNDKVQNQemstLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEME 2971
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEE----LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2972 TEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQE 3051
Cdd:COG1196    364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1838138447 3052 LTVQLNEREASQEE--AQKEVLTHAEVTLAKADAALRQREAELARLRAEHQALKAELTE 3108
Cdd:COG1196    444 LEEAAEEEAELEEEeeALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3615-3909 3.61e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 3.61e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3615 RELQIEQSRSELLEKRLDDtqKELGDERQLSANQKELKLQDKTRLERLLAEAESRLAEIHSTLAEAHRKVDEERERYSRQ 3694
Cdd:COG1196    216 RELKEELKELEAELLLLKL--RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3695 VDELSRrheadATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRSKWEEEDRARRAELQREKEAAIQQRVAVE 3774
Cdd:COG1196    294 LAELAR-----LEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3775 TLKEQKQETccalemERARSTQQGVELTELKEKLHLIKDKEREREEQWERERRKGRQEQMERERRQERTNDKLcELEMLR 3854
Cdd:COG1196    369 EAEAELAEA------EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE-EEEEEE 441

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1838138447 3855 QQDQQRMQELQHTLVELEREEKEMSAQRLRQHNIAASSQHLQSDFQTGSAQHNQQ 3909
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
PTZ00121 PTZ00121
MAEBL; Provisional
 1316-2045 8.44e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.55  E-value: 8.44e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1316 RSARVDDIERLKTEFNEQKREIKEQN---EAELESLRRYFEQRLRATEEGHREEIALLQLRLVERALEESVIRTADDSFS 1392
Cdd:PTZ00121  1062 AKAHVGQDEGLKPSYKDFDFDAKEDNradEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARK 1141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1393 SISQGQAEEEKDHLFSDAVFKLEKHKEALDNVSLQLEEKHSMDLSyLQSSMSLSFKEELQQVQSdiTDQYYEELQELKTR 1472
Cdd:PTZ00121  1142 AEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE-VRKAEELRKAEDARKAEA--ARKAEEERKAEEAR 1218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1473 HAMELEKLRAklsdhhVKELTRAHLEAARQVEVEVEQRMWCLTEELQSRMTIIHTLDSKLAALSKQHDAEVQRNTQKLKQ 1552
Cdd:PTZ00121  1219 KAEDAKKAEA------VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA 1292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1553 EfagELVHLEEALKQEREDVQEERKRWREELQEKHQaELSALRSELDREMESERTRLEKELHEEKERLKTLQAALDNDES 1632
Cdd:PTZ00121  1293 D---EAKKAEEKKKADEAKKKAEEAKKADEAKKKAE-EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA 1368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1633 PQvlivRQRLEAQYDGELQRAKScmatEVKELTARLQEQGEERLHQAQERlhgEKAALEQSLAQKYEASLAELKSKHQSE 1712
Cdd:PTZ00121  1369 AE----KKKEEAKKKADAAKKKA----EEKKKADEAKKKAEEDKKKADEL---KKAAAAKKKADEAKKKAEEKKKADEAK 1437

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1713 LEHERAALLNKERDTLDAKHKAQldslSASHRDQLTATAAELKSKHSAELVALEA---ALDSKRKADieSLEGVLKETNQ 1789
Cdd:PTZ00121  1438 KKAEEAKKADEAKKKAEEAKKAE----EAKKKAEEAKKADEAKKKAEEAKKADEAkkkAEEAKKKAD--EAKKAAEAKKK 1511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1790 AQlEASEAELTRKHQEEKDELEMRMLGNMDTLESTYLKEVQALRDEIIQLEERHCRGLNLQKSEHRQVLERHASEQLSIR 1869
Cdd:PTZ00121  1512 AD-EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1870 EELRKELAQLHIEKFSAMAVELShvhktelTAQKEALDTDHCKALETLKKQVLEVEQQHSLALQELSQTCTADKEQLLAQ 1949
Cdd:PTZ00121  1591 EARIEEVMKLYEEEKKMKAEEAK-------KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA 1663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1950 QQLQLQDLRgvSARELEACRRELEEESSRQRQHFLEEVELLKVQ----SEERLQDRINRLKTEfEEQKEARLEDLKRSFT 2025
Cdd:PTZ00121  1664 AEEAKKAEE--DKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelkkKEAEEKKKAEELKKA-EEENKIKAEEAKKEAE 1740

                          730       740
                   ....*....|....*....|
gi 1838138447 2026 SEQEEKERSYTDKMSQLTIQ 2045
Cdd:PTZ00121  1741 EDKKKAEEAKKDEEEKKKIA 1760
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1868-2466 1.19e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 1.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1868 IREELRKELAQLHI-----EKFSAMAVELSHVHKTELTAQKEALDTDhckaLETLKKQVLEVEQQHSLALQELSQTCTA- 1941
Cdd:COG1196    194 ILGELERQLEPLERqaekaERYRELKEELKELEAELLLLKLRELEAE----LEELEAELEELEAELEELEAELAELEAEl 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1942 DKEQLLAQQQLQLQDLRGVSARELEACRRELEEESSRQRqhfleevellkvQSEERLQDRINRLKTEfEEQKEARLEDLK 2021
Cdd:COG1196    270 EELRLELEELELELEEAQAEEYELLAELARLEQDIARLE------------ERRRELEERLEELEEE-LAELEEELEELE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2022 RsftsEQEEKERSYTDKMSQLTIQLQQLDTVVAQLRAEVGCLQGELEGKRSEMETLDTLLQRRQRETQEGGNLLKMLTDD 2101
Cdd:COG1196    337 E----ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2102 LQAGKEERRKLNQANEKLKKVLIEMIRSTIATEDMIGQKICARAKTSEHGSHQRSSTGNEDAQESGISVADMSSQDMELT 2181
Cdd:COG1196    413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2182 HLLCESLLVSDTQINPGGEEAALNACSRLRH-TVDTLLDLLNHANKQLEQTHG--FHHSLEEKFSQGREDSAQLLVQHKI 2258
Cdd:COG1196    493 LLLLLEAEADYEGFLEGVKAALLLAGLRGLAgAVAVLIGVEAAYEAALEAALAaaLQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2259 LLEQLDQEAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERLVEEL---EDLKVKLHQMQGLTAELDGLRLK 2335
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTlvaARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2336 HQELSEEHSLLLRQKEHLSAGLGEREKALLAETERLTQDRLDLQRQAEKDHKSLSLRLRALERDLEEKETQDLETEQhhk 2415
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ--- 729

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1838138447 2416 thNEDLNQRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQ 2466
Cdd:COG1196    730 --LEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3572-3840 1.37e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3572 QRKDREKEERREALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKEl 3651
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE- 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3652 klqDKTRLERLLAEAESRLAEIHSTLAEAHRKVDEERERYSRQVDELSRRHEADATRDRKFISDMRAQLEQERRQGEELA 3731
Cdd:COG1196    317 ---RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3732 AVMNKLRAELLQSRSkwEEEDRARRAELQREKEAAIQQRVAVETLKEQKQETccalemERARSTQQGVELTELKEKLHLI 3811
Cdd:COG1196    394 AAAELAAQLEELEEA--EEALLERLERLEEELEELEEALAELEEEEEEEEEA------LEEAAEEEAELEEEEEALLELL 465

                          250       260
                   ....*....|....*....|....*....
gi 1838138447 3812 KDKEREREEQWERERRKGRQEQMERERRQ 3840
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLL 494
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3512-3884 2.33e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 2.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3512 RAELEESQKQLKCAHDTQQEHKNKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERALSQRKDREKEERREALHVSSEQ 3591
Cdd:COG1196    262 LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3592 QRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKELKLQDKTRLERLLAEAESRLA 3671
Cdd:COG1196    342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3672 EIhSTLAEAHRKVDEERERYSRQVDELSRRHEADATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAE------LLQSR 3745
Cdd:COG1196    422 EL-EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAaarlllLLEAE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3746 SKWEEEDRARRAELQREKEAAIQQRVAVETLKEQKQETCCALEMERARSTQQGVELTELKEKLHLIKDKEREREEQWERE 3825
Cdd:COG1196    501 ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD 580

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1838138447 3826 RRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQHTLVELEREEKEMSAQRLR 3884
Cdd:COG1196    581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2208-2870 4.06e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 4.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2208 SRLRHTVDTLLDLLNHANKQLEQ-THGFHHSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKLKSELQLEYHKTEglleg 2286
Cdd:TIGR02169  261 SELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL----- 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2287 yvAEKALLEESLQQKEVQEERLVEELEDLKVKLHQmqgLTAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGE---REKA 2363
Cdd:TIGR02169  336 --AEIEELEREIEEERKRRDKLTEEYAELKEELED---LRAELEEVDKEFAETRDELKDYREKLEKLKREINElkrELDR 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2364 LLAETERLTQDRLDLQRQA----------EKDHKSLSLRLRALERDLEE-KETQDLETEQHHKTHNE--DLNQRVQALEK 2430
Cdd:TIGR02169  411 LQEELQRLSEELADLNAAIagieakinelEEEKEDKALEIKKQEWKLEQlAADLSKYEQELYDLKEEydRVEKELSKLQR 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2431 QL---KHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQTASVDNK---------GHRFQDLVLQVESLQA----IIKDK 2494
Cdd:TIGR02169  491 ELaeaEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaaGNRLNNVVVEDDAVAKeaieLLKRR 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2495 TEDHDSLIAANQQAQR-----------------DLAECNEEIDK--------------------LAGRIR--ELEQALLN 2535
Cdd:TIGR02169  571 KAGRATFLPLNKMRDErrdlsilsedgvigfavDLVEFDPKYEPafkyvfgdtlvvedieaarrLMGKYRmvTLEGELFE 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2536 DAE----GKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHCYHDNQREPTQELSDALDLAQ 2611
Cdd:TIGR02169  651 KSGamtgGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2612 QS-------------LRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADH-VNELQEQIDALKENVSAL 2677
Cdd:TIGR02169  731 EEeklkerleeleedLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSrIPEIQAELSKLEEEVSRI 810

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2678 --------AILNEEREEQ-----SEAEEPEEENFPSALIEEKNQEIDHLNAEIQRLEQELDNTEDN-KALEAELEDLRSQ 2743
Cdd:TIGR02169  811 earlreieQKLNRLTLEKeylekEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAlRDLESRLGDLKKE 890

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2744 VEHLQ---SEVMRVRQDTQEEVERLHEVISTLQAELATLGPNLHEVSDSQDGDsinpSPAPSPEPDNYTVQEQARRGGAN 2820
Cdd:TIGR02169  891 RDELEaqlRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED----EEIPEEELSLEDVQAELQRVEEE 966

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1838138447 2821 SLKQELSLSYSASS-HSLRSRFKTLQSQLEAAAAEKEGLERLLLTQEEEYR 2870
Cdd:TIGR02169  967 IRALEPVNMLAIQEyEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKR 1017
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2419-3163 4.65e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 4.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2419 EDLNQRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQTASvdnkghrfqdlvlQVESLQAIIKDKTEDH 2498
Cdd:TIGR02169  194 DEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIER-------------QLASLEEELEKLTEEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2499 DSLIAANQQAQRDLAECNEEIDKLAgrirELEQALLndaegKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQI 2578
Cdd:TIGR02169  261 SELEKRLEEIEQLLEELNKKIKDLG----EEEQLRV-----KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2579 SALQSKVDETRHCYHDNQREPTQelsdaldlAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNAD 2658
Cdd:TIGR02169  332 DKLLAEIEELEREIEEERKRRDK--------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2659 HVNELQEQIDALKENVSALAILNEEREEQSEAeepeeenfpsalIEEKNQEIDHLNAEIQRLEQELDNT-EDNKALEAEL 2737
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELADLNAAIAGIEAK------------INELEEEKEDKALEIKKQEWKLEQLaADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2738 EDLRSQVEHLQSEvmrvRQDTQEEVERLHEVISTLQAELATLGPNLHEVSDSQDGDSINPSPAPSPEPDNYTVQEQARRG 2817
Cdd:TIGR02169  472 YDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGN 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2818 GANSLKQELSLSYSASSHSLRSR----------FKTLQSQLEAAAAEKEGLERL---LLTQEEEYRG------------H 2872
Cdd:TIGR02169  548 RLNNVVVEDDAVAKEAIELLKRRkagratflplNKMRDERRDLSILSEDGVIGFavdLVEFDPKYEPafkyvfgdtlvvE 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2873 GEEFGKRL-------TAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERKLSEEVNDkvQNQEMSTLRDKNLHLNSLIA 2945
Cdd:TIGR02169  628 DIEAARRLmgkyrmvTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEG--LKRELSSLQSELRRIENRLD 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2946 EVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLR 3025
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3026 RREG-----KLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEV---------LTHAEVTLAKADAALRQREAE 3091
Cdd:TIGR02169  786 ARLShsripEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIqelqeqridLKEQIKSIEKEIENLNGKKEE 865

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1838138447 3092 LARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRallNLETDNQRLKAQLRALQEDLAVQEEELA 3163
Cdd:TIGR02169  866 LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE---ELEAQIEKKRKRLSELKAKLEALEEELS 934
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1867-2623 5.79e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 5.79e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1867 SIREELRKELAQL-----HIEKFSAMAVELSHVHKTELTAQKEALDTDhckaLETLKKQVLEVEQQHSlALQELSQTCTA 1941
Cdd:TIGR02169  191 LIIDEKRQQLERLrrereKAERYQALLKEKREYEGYELLKEKEALERQ----KEAIERQLASLEEELE-KLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1942 DKEQLLAQQQLQLQDLRGVSARELEACRRELEEESSRQRQhfLEEVELLKVQSEERLQDRINRLKTEFEEQKEaRLEDLK 2021
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIAS--LERSIAEKERELEDAEERLAKLEAEIDKLLA-EIEELE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2022 RSFTSEQEEKER------SYTDKMSQLTIQLQQLDTVVAQLRAEVGCLQGELEGKRSEME----TLDTLLQRRQRETQEG 2091
Cdd:TIGR02169  343 REIEEERKRRDKlteeyaELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINelkrELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2092 GNL----------LKMLTDDLQAGKEERRKLNQANEKLKKVLI---EMIRSTIATEDMIGQKIcaRAKTSEHGSHQRSST 2158
Cdd:TIGR02169  423 ADLnaaiagieakINELEEEKEDKALEIKKQEWKLEQLAADLSkyeQELYDLKEEYDRVEKEL--SKLQRELAEAEAQAR 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2159 GNEDAQESGISVADMSSQDMELTHLLCESLLVSDTQINPGGEEAALNacsRLRHTVDTLLDLLNHANKQLEQTHG----- 2233
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGN---RLNNVVVEDDAVAKEAIELLKRRKAgratf 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2234 --------FHHSLEEKFSQGREDSAQLLV--------------QHKILLEQLDQEAKLKSELQLE------YHKTEGLLE 2285
Cdd:TIGR02169  578 lplnkmrdERRDLSILSEDGVIGFAVDLVefdpkyepafkyvfGDTLVVEDIEAARRLMGKYRMVtlegelFEKSGAMTG 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2286 GYVAEKALLEESLQQKEvQEERLVEELEDLKvklhqmqgltAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGEREKall 2365
Cdd:TIGR02169  658 GSRAPRGGILFSRSEPA-ELQRLRERLEGLK----------RELSSLQSELRRIENRLDELSQELSDASRKIGEIEK--- 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2366 aETERLTQDRLDLQRQAEKdhksLSLRLRALERDLEEKETQDLETEQHHKTHNEDLNQRVQALEKQLKHDRQfieEQAVE 2445
Cdd:TIGR02169  724 -EIEQLEQEEEKLKERLEE----LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH---SRIPE 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2446 REHERDEFQQEIRSLEAQLRQTASVDNKGH-RFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAG 2524
Cdd:TIGR02169  796 IQAELSKLEEEVSRIEARLREIEQKLNRLTlEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEA 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2525 RIRELEQALlndAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHCYHDNQREPTQELS 2604
Cdd:TIGR02169  876 ALRDLESRL---GDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS 952

                          810
                   ....*....|....*....
gi 1838138447 2605 daLDLAQQSLRSKEQEVEA 2623
Cdd:TIGR02169  953 --LEDVQAELQRVEEEIRA 969
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1760-2533 1.03e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 1.03e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1760 AELVALEAALDSKRKAdIESLEGVLKETnQAQLEASEAELTRkHQEEKDELEMRMLGNMDTLESTYlKEVQALRDEIIQL 1839
Cdd:TIGR02168  232 LRLEELREELEELQEE-LKEAEEELEEL-TAELQELEEKLEE-LRLEVSELEEEIEELQKELYALA-NEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1840 EER--HCRGLNLQKSEHRQVLERHASEQLSIREELRKELAQLHIEKFSAMA-VELSHVHKTELTAQKEALDtdhcKALET 1916
Cdd:TIGR02168  308 RERlaNLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAeLEELEAELEELESRLEELE----EQLET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1917 LKKQVLEVEQQHSLA---LQELSQTCTADKEQLLAQQQLQLQDLRGVSARELEACRRELEEEssRQRQHFLEEVELLKVQ 1993
Cdd:TIGR02168  384 LRSKVAQLELQIASLnneIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL--EEELEELQEELERLEE 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1994 SEERLQDRINRLKTEF--EEQKEARLEDLKRSFTSEQEEKErSYTDKMSQLTIQLQQLDTVVAQLraevgclqGELEGKR 2071
Cdd:TIGR02168  462 ALEELREELEEAEQALdaAERELAQLQARLDSLERLQENLE-GFSEGVKALLKNQSGLSGILGVL--------SELISVD 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2072 SEMET-LDTLLqrrqretqeGGNLLKMLTDDLQAGKEERRKLNQANEKLKKVL----IEMIRSTIATEDMIGQKICARAK 2146
Cdd:TIGR02168  533 EGYEAaIEAAL---------GGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLpldsIKGTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2147 TSEHGSHQRSSTGNEDAQESGISVADMSSQDMELTHLL-CESLLVS--DTQINPGG------EEAALNACSR------LR 2211
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLrPGYRIVTldGDLVRPGGvitggsAKTNSSILERrreieeLE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2212 HTVDTLLDLLNHANKQLEQTHGFHHSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKLKSELQLEYHKTEGLLEGYVAEK 2291
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2292 ALLEESLQQKEVQEERLVEELEDLKVKLHQMQG----LTAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGEREKALLAE 2367
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEelkaLREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2368 TERLTQDRLDLQRqAEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLNQRVQALE------KQLKHDRQFIEE 2441
Cdd:TIGR02168  844 EEQIEELSEDIES-LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELReleskrSELRRELEELRE 922

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2442 QAVEREHERDEFQQEIRSLEAQLRQTASV--DNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEI 2519
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEYSLtlEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERY 1002

                          810
                   ....*....|....
gi 1838138447 2520 DKLAGRIRELEQAL 2533
Cdd:TIGR02168 1003 DFLTAQKEDLTEAK 1016
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 121-854 1.26e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 1.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  121 KEQLKQLQEAVEKRNEIIARLSSNLQEALASRDQVQLEAQSLAGQIQGLQRQLQQTSVEFLRIKSQ------------SG 188
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQkqilrerlanleRQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  189 AEVLNTRQPHGRCSQD---ADLNHKEAPSGSAAPETISCVEGFSTDTA----LEKLRVELEEERKNSQRIYAELALEMEK 261
Cdd:TIGR02168  318 LEELEAQLEELESKLDelaEELAELEEKLEELKEELESLEAELEELEAeleeLESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  262 HQHVLSLLEKEKNSREEEQKEKEEQLQDLQM-----QFSLVQTQCLEMQQYKEEKEKLNREVLELRKRLQEEADAERRLG 336
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEELLKkleeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  337 EEVASSALRLQRQEEEMLRLKEEHREEVEGVRQLLEEREKE----------LKFRE------EEVLGLKASK---NRQNK 397
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvlselISVDEgyeaaiEAALGGRLQAvvvENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  398 AKAGFSFDEKVNLD-----EAELETGPVENSMNVSVDILMERYMSSHRPAHSQSSVASDSLE-RCGQLDISADYsfelnS 471
Cdd:TIGR02168  558 AKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyLLGGVLVVDDL-----D 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  472 EVLGDEPLLSISNRFLEEDD---NRHNTSTPQCSPGiplpdNSNPQSPSQWLYDSTPD-ELETSKLSEQQFEQTDLEKEL 547
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDGdlvRPGGVITGGSAKT-----NSSILERRREIEELEEKiEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  548 --LNQQCGELRDELLLKDRDLNVLREEVINTAEELEEARSRWGQVTEELRQALWELEEEKEKKRLAEEEMNLKAHEQDNL 625
Cdd:TIGR02168  708 eeLEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  626 KSKLSALMEE--------REKEKAVLLTGKEAAETSL----LVPAITPSEEEDELVGELKKKKQQDLLLSQQEIKQPAIS 693
Cdd:TIGR02168  788 EAQIEQLKEElkalrealDELRAELTLLNEEAANLRErlesLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  694 AEQILELRDDKPLQTLQVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNDLQEQIDALKAQCEHLllhLEE 773
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL---QER 944

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  774 MTTTHKTTAALIDEKTTELDRTSKELERtraqvvnvqtEVDRLQGELEK----SLDSLDTAEQVK---SELESQIFCLKQ 846
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARR----------RLKRLENKIKElgpvNLAAIEEYEELKeryDFLTAQKEDLTE 1014


                   ....*...
gi 1838138447  847 NLAKLEEA 854
Cdd:TIGR02168 1015 AKETLEEA 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3506-3889 1.41e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 1.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3506 QVESQLRAELEESQKQlkcahdtQQEHKNKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERALSQRKDREKEERREAL 3585
Cdd:COG1196    347 EEAEEELEEAEAELAE-------AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3586 HVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKELKLQDKTRLERLLAE 3665
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3666 AESRLAEIHSTLAEA--------HRKVDEER---ERYSRQVDELSRRHEADATRDRKFISDMRAQLEQERRQGEELAAVM 3734
Cdd:COG1196    500 EADYEGFLEGVKAALllaglrglAGAVAVLIgveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL 579

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3735 NKLRA-ELLQSRSKWEEEDRARRAELQREKEAAIQQRVAVETLKEQKQETCCALEMERARSTQQG--VELTELKEKLHLI 3811
Cdd:COG1196    580 DKIRArAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGrlREVTLEGEGGSAG 659

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1838138447 3812 KDKEREREEQWERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQHTLVELEREEKEMSAQRLRQHNIA 3889
Cdd:COG1196    660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 694-1325 1.50e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  694 AEQILELRDDkpLQTLQVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNA----------DHVNDLQEQIDALKAQ 763
Cdd:COG1196    212 AERYRELKEE--LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAeleaeleelrLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  764 CEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDRLQGELEKSLDSLDTAEQVKSELESQIFC 843
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  844 LKQNLAKLEEAQAQTEQEREERRRKEEEMDDQIKKMEQVLEEELEQFESLLKAKDVELSEAKEkweeesqeketellgvr 923
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE----------------- 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  924 hhleeqRREREEEVKALLEKQVLAVEEETERLKTSHQQEIKDLMERHRQEISELNTHLESEQLKQQVNMEEEQKRQIS-F 1002
Cdd:COG1196    433 ------LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1003 IKQVTEREHERMLSELSAKHNEELtqlrtEVSLELRESMEAAHQAELLQHQVQKRSELEAMRLSLTNAHVSQLEQESALT 1082
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGAVAVLI-----GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1083 EAQGSPRDTFAQEIALLKAQHQAELDHIRQQEKLRELQqqpmndlqqqwETLVAQERAAMEEEQAKDIQALRsqwdkNAE 1162
Cdd:COG1196    582 IRARAALAAALARGAIGAAVDLVASDLREADARYYVLG-----------DTLLGRTLVAARLEAALRRAVTL-----AGR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1163 SRESNLQMFLSEMQNSLTATQTdlTQTLKALSQTQAELQRSGAKLQELQTSSKDMNQELEAELEQACAdrdaaarsLEEL 1242
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSR--RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE--------AEEE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1243 MSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLESMRTSRQELG-----------ELKE 1311
Cdd:COG1196    716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGpvnllaieeyeELEE 795

                          650
                   ....*....|....
gi 1838138447 1312 QLLARSARVDDIER 1325
Cdd:COG1196    796 RYDFLSEQREDLEE 809
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2359-3162 1.90e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.14  E-value: 1.90e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2359 EREKALLAETERLTQdRLDLQRQAEKDHKSLSLRLRALERDLEEKETQDLETEqhhkthNEDLNQRVQALEKQLKHDRQF 2438
Cdd:pfam02463  173 EALKKLIEETENLAE-LIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE------YLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2439 IEEQAVEREHERDEFQQEIRSLEAQLRQTASVDNkghrfqdlvlQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEE 2518
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK----------EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEK 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2519 IDKLAGRIRELEQALLNDaegKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKvdetrhcyhdnQRE 2598
Cdd:pfam02463  316 LKESEKEKKKAEKELKKE---KEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAK-----------KKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2599 PTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALA 2678
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2679 ILNEEREEQSEAEEPEEenfpsaliEEKNQEIDHLNAEIQRLEQELDNTEDNKALEAELEDLRSQVEHLQSEVMRVRQDT 2758
Cdd:pfam02463  462 KDELELKKSEDLLKETQ--------LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGD 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2759 QEEVERLHEV--ISTLQAELATLGPNLHEVSDSQDGDSINPSPAPSPEPDNYTVQEQARRGGANSLKQELSLSYSASSHS 2836
Cdd:pfam02463  534 LGVAVENYKVaiSTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATL 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2837 LRSRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERK 2916
Cdd:pfam02463  614 EADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEE 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2917 LSEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDM 2996
Cdd:pfam02463  694 ILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKE 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2997 EELVDEERIKIKTLKTV-KGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEVLTHAE 3075
Cdd:pfam02463  774 KELAEEREKTEKLKVEEeKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3076 VTLAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDL 3155
Cdd:pfam02463  854 EELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKY 933


                   ....*..
gi 1838138447 3156 AVQEEEL 3162
Cdd:pfam02463  934 EEEPEEL 940
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1733-2557 2.27e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 2.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1733 KAQLDSLsashrdQLTATAAELKSKHSAELVALEAALDSKR----KADIESLEGVLKETNQaQLEASEAELTRKhQEEKD 1808
Cdd:TIGR02168  199 ERQLKSL------ERQAEKAERYKELKAELRELELALLVLRleelREELEELQEELKEAEE-ELEELTAELQEL-EEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1809 ELEMRMlGNMDTLESTYLKEVQALRDEIIQLEErhcrglnlQKSEHRQVLERHASEQLSIREELRKELAQLHIEKFS-AM 1887
Cdd:TIGR02168  271 ELRLEV-SELEEEIEELQKELYALANEISRLEQ--------QKQILRERLANLERQLEELEAQLEELESKLDELAEElAE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1888 AVELSHVHKTELTAQKEALDTDHcKALETLKKQVLEVEQQH-----SLALQELSQTCTADKEQLLAQQQLQLQDLRGVSA 1962
Cdd:TIGR02168  342 LEEKLEELKEELESLEAELEELE-AELEELESRLEELEEQLetlrsKVAQLELQIASLNNEIERLEARLERLEDRRERLQ 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1963 RELEACRRELEEESSRQRQHFLEEVELLKVQSEERLQDRINRLKTEFEEQKEARLEDLKrsfTSEQEEKERSYTDKMSQL 2042
Cdd:TIGR02168  421 QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA---AERELAQLQARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2043 TIQLQQLDTVVAQLRAE-------VGCLqGELEGKRSEMET-LDTLLqrrqretqeGGNLLKMLTDDLQAGKEERRKLNQ 2114
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNqsglsgiLGVL-SELISVDEGYEAaIEAAL---------GGRLQAVVVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2115 ANEKLKKVL----IEMIRSTIATEDMIGQKICARAKTSEHGSHQRSSTGNEDAQESGISVADMSSQDMELTHLL-CESLL 2189
Cdd:TIGR02168  568 NELGRVTFLpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLrPGYRI 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2190 VS--DTQINPGGeeaALNACSRLRHTVdtlldLLNHANKQLEqthgfhhsLEEKFSQGREDSAQLLVQHKILLEQLDQEA 2267
Cdd:TIGR02168  648 VTldGDLVRPGG---VITGGSAKTNSS-----ILERRREIEE--------LEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2268 KLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERLVEELEDLKVklhQMQGLTAELDGLRLKHQELSEEHSLLL 2347
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA---EIEELEERLEEAEEELAEAEAEIEELE 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2348 RQKEHLSAGLGEREKALLAETERLTQDRLDLQRQAEkdhkslslRLRALERDLEEKETQDLETEQHHkthnEDLNQRVQA 2427
Cdd:TIGR02168  789 AQIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLEDLEEQI----EELSEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2428 LEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLrqtasvdnkgHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQ 2507
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLR----------SELEELSEELRELESKRSELRRELEELREKLAQ 926

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2508 AQRDLAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSKLRE 2557
Cdd:TIGR02168  927 LELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1796-2406 3.08e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 3.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1796 EAELTRKHQEEKDELEmRMLGNMDTLESTYLKEVQALRDEIIQLEERHCRGLNLQKSEHRQVLERHASEQLSIREELRKE 1875
Cdd:COG1196    208 QAEKAERYRELKEELK-ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1876 LAQLHIEKFSAMAVELSHVHKTELTAQKEAldtdhckALETLKKQVLEVEQQHSLALQELSQTCTADKEQllaqqqlqlq 1955
Cdd:COG1196    287 QAEEYELLAELARLEQDIARLEERRRELEE-------RLEELEEELAELEEELEELEEELEELEEELEEA---------- 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1956 dlrgvsARELEACRRELEEESSRQRQhfLEEVELLKVQSEERLQDRINRLKTEfEEQKEARLEDLKRSFTSEQEEKERsY 2035
Cdd:COG1196    350 ------EEELEEAEAELAEAEEALLE--AEAELAEAEEELEELAEELLEALRA-AAELAAQLEELEEAEEALLERLER-L 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2036 TDKMSQLTIQLQQLDTVVAQLRAEVGCLQGELEGKRSEMETLDTLLQRRQRETQEGGNLLkmltDDLQAGKEERRKLNQA 2115
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL----AELLEELAEAAARLLL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2116 NEKLKKVLIEMIRSTIATEDMIGQKICARAKTSEhgshqrssTGNEDAQESGISVADMSSqdmeLTHLLCESLLVSDTQI 2195
Cdd:COG1196    496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL--------IGVEAAYEAALEAALAAA----LQNIVVEDDEVAAAAI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2196 NpGGEEAALNACSRLRHTVDTLLDLLNHANKQLEQTHGF--HHSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKLKSEL 2273
Cdd:COG1196    564 E-YLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2274 QLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERLVEELEDLKVKLHQMQGLTAELDGLRLKHQELSEEHSLLLRQKEHL 2353
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1838138447 2354 SAGLGEREKALLAETERLTQDRLDLQRQAEKDHKSLSLRLRALERDLEEKETQ 2406
Cdd:COG1196    723 EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2874-3793 4.06e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 4.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2874 EEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERKLSEEVNDK---VQNQEMSTLRDKNLHLNSLIAEVQKK 2950
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELelaLLVLRLEELREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2951 EQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGK 3030
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3031 LQEEIENLRQEATSMRACIQELTVQLNEREASQEEAqkevlthaEVTLAKADAALRQREAELARLRAEHQALKAELTEVK 3110
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELEAELEEL--------ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3111 QGLSTSTERAEKLHEEGQTKDRALLNletdnqrlkAQLRALQEDLAVQEEELAYQQRELQQLRqhcdqqdtlphQRGHTQ 3190
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEE---------AELKELQAELEELEEELEELQEELERLE-----------EALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3191 KDISHRAFEDLVSVSRDDVSLSSP-EVLRRLECSEDRIPE--------RFRASAIGSRLSE---FSALNSTGLDLHHAKT 3258
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARlDSLERLQENLEGFSEgvkallknQSGLSGILGVLSElisVDEGYEAAIEAALGGR 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3259 SPRVVMESprsrtitpepvTQSSRSPISGSVSVNDNFSMLDSLDTDKMRELEDLDMTTPSSPLGSTSSLSAPEWASDGYG 3338
Cdd:TIGR02168  547 LQAVVVEN-----------LNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3339 SNVSSELGARLKVEleqterldaqfleylrcrgmnptvNTDSAAGsmsysdellspelqclLKKVYQESCRILTLSKRRA 3418
Cdd:TIGR02168  616 KALSYLLGGVLVVD------------------------DLDNALE----------------LAKKLRPGYRIVTLDGDLV 655

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3419 TSstyphvsdlrafalshtehhseGGSIVLDRRDNPSSIppmgwQQEKRALQEtvvaLRELLCRMAQRPTQTDHRVEGDW 3498
Cdd:TIGR02168  656 RP----------------------GGVITGGSAKTNSSI-----LERRREIEE----LEEKIEELEEKIAELEKALAELR 704

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3499 HGDRVDGQVESQLRAELEESQKQLKCAHDTQQEHKNKMQSVRVAVAEgeeaLRREQVRVQELQQQLEQERALSQRKDREK 3578
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTELEAEIEELEERLEEAEEELAEA 780

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3579 EERREALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKElklqDKTR 3658
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE----DIES 856

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3659 LERLLAEAESRLAEIHSTLAEAHRKVDEERERYSRQVDELSRRhEADATRDRKFISDMRAQLEQERRQGEELAAVMNKLR 3738
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1838138447 3739 AELLQSRSKWeeedrarRAELQREKEAAIQQRVAVETLKEQKQETCCALEMERAR 3793
Cdd:TIGR02168  936 VRIDNLQERL-------SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2306-2791 6.24e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 6.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2306 ERLVEELEDLK------VKLHQMQGLTAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGEREKALLAEteRLTQDRLDLQ 2379
Cdd:COG4913    228 DALVEHFDDLErahealEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEA--ELEELRAELA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2380 RQAEkdhkslslRLRALERDLEEKETQDLETEQHHKTHNedlNQRVQALEKQLKHdrqfIEEQAVEREHERDEFQQEIRS 2459
Cdd:COG4913    306 RLEA--------ELERLEARLDALREELDELEAQIRGNG---GDRLEQLEREIER----LERELEERERRRARLEALLAA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2460 LEAQLRQTASVdnkghrFQDLVLQV----ESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRI--------- 2526
Cdd:COG4913    371 LGLPLPASAEE------FAALRAEAaallEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsniparlla 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2527 --RELEQALLNDAEGKRSISQL--------------EQELHRSKLR----EQELSQDKQALEQQQLSNRLQIsalqSKVD 2586
Cdd:COG4913    445 lrDALAEALGLDEAELPFVGELievrpeeerwrgaiERVLGGFALTllvpPEHYAAALRWVNRLHLRGRLVY----ERVR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2587 ETRHCYHDNQREPtQELSDALDLAQQSLRskeQEVEAVVGQ---------LETLQ-------------SELGLKEVELKH 2644
Cdd:COG4913    521 TGLPDPERPRLDP-DSLAGKLDFKPHPFR---AWLEAELGRrfdyvcvdsPEELRrhpraitragqvkGNGTRHEKDDRR 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2645 LALQLEQLTNQNADHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEENFpSALIEEKNQEIDH--LNAEIQRLEQ 2722
Cdd:COG4913    597 RIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDVasAEREIAELEA 675

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1838138447 2723 ELDNTEDN----KALEAELEDLRSQVEHLQSEvmrvRQDTQEEVERLHEVISTLQAELATLGPNLHEVSDSQD 2791
Cdd:COG4913    676 ELERLDASsddlAALEEQLEELEAELEELEEE----LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR 744
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2812-3161 7.60e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.90  E-value: 7.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2812 EQARRGGANSLKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEGLErlllTQEEEYRGHGEEFGKRLTAEREKADKLQ 2891
Cdd:PRK02224   179 ERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYE----EQREQARETRDEADEVLEEHEERREELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2892 SVltlkEAELDEVKAQKEGDAEERK-LSEEVNDkvQNQEMSTLRDKNLHLNS--------------LIAEVQKKEQERVT 2956
Cdd:PRK02224   255 TL----EAEIEDLRETIAETEREREeLAEEVRD--LRERLEELEEERDDLLAeaglddadaeaveaRREELEDRDEELRD 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2957 EMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREG------- 3029
Cdd:PRK02224   329 RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGdapvdlg 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3030 -------KLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQ-------KEVLTHAEvTLAKADAALRQREAELARL 3095
Cdd:PRK02224   409 naedfleELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpVEGSPHVE-TIEEDRERVEELEAELEDL 487

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1838138447 3096 RAEHQALKAELTEVKQgLSTSTERAEKLHEEGQTKDRALLNLET--DNQRLKAQ-LRALQEDLAVQEEE 3161
Cdd:PRK02224   488 EEEVEEVEERLERAED-LVEAEDRIERLEERREDLEELIAERREtiEEKRERAEeLRERAAELEAEAEE 555
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1099-1875 8.52e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 8.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1099 LKAQHQAELDHIRQQEKLRELQQQ----PMNDLQQQWETLVAQERAA--MEEEQAKDIQALRSQWDKNaESRESNLQMFL 1172
Cdd:TIGR02168  205 LERQAEKAERYKELKAELRELELAllvlRLEELREELEELQEELKEAeeELEELTAELQELEEKLEEL-RLEVSELEEEI 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1173 SEMQ---NSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQT---SSKDMNQELEAELEQACADRDAAARSLEELMSSH 1246
Cdd:TIGR02168  284 EELQkelYALANEISRLEQQKQILRERLANLERQLEELEAQLEeleSKLDELAEELAELEEKLEELKEELESLEAELEEL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1247 KAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKnseqEVGQLWTQLESMRTSRQELGELKEQLLARSARVDdIERL 1326
Cdd:TIGR02168  364 EAELEELESRLEELEEQLETLRSKVAQLELQIASLNN----EIERLEARLERLEDRRERLQQEIEELLKKLEEAE-LKEL 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1327 KTEFNEQKREIKEQNEAEleslrryfeQRLRATEEGHREEIALLQLRLVERALEESVIRTADDSFSSIsqgQAEEEKdhl 1406
Cdd:TIGR02168  439 QAELEELEEELEELQEEL---------ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERL---QENLEG--- 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1407 FSDAVFKLEKHKEALDNVSLQLEEKHSMDLSYlQSSMSLSFKEELQQVQSDITDQYYEELQELKtrhamELEKLRAK--- 1483
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILGVLSELISVDEGY-EAAIEAALGGRLQAVVVENLNAAKKAIAFLK-----QNELGRVTflp 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1484 LSDHHVKELTRAHLEAARQVEVEVEQRMWCLTEELQSRMTIIHTLDSKLAALSKQHDAEVQRNTQKLKQEF--AGELVHL 1561
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVtlDGDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1562 EEALKQ---EREDVQEERKRWREELQEKhQAELSALRSELDREmesertrlekelheekerLKTLQAALDNDESpQVLIV 1638
Cdd:TIGR02168  658 GGVITGgsaKTNSSILERRREIEELEEK-IEELEEKIAELEKA------------------LAELRKELEELEE-ELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1639 RQRLEaqydgELQRAKSCMATEVKELTARlQEQGEERLHQAQERLHGEKAALEQSLAQKYEASLAELKSKHQSELEHERA 1718
Cdd:TIGR02168  718 RKELE-----ELSRQISALRKDLARLEAE-VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1719 ALLNKERDTLDAKHKAQLDSLSASHRD--QLTATAAELKSKHSAELVALEAALDSKRK--ADIESLEGVLKETnQAQLEA 1794
Cdd:TIGR02168  792 EQLKEELKALREALDELRAELTLLNEEaaNLRERLESLERRIAATERRLEDLEEQIEElsEDIESLAAEIEEL-EELIEE 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1795 SEAELTrKHQEEKDELEMRMLGNMDTLESTyLKEVQALRDEIIQLEERhCRGLNLQKSEHRQVLERHASEQLSIREELRK 1874
Cdd:TIGR02168  871 LESELE-ALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRE-LEELREKLAQLELRLEGLEVRIDNLQERLSE 947


                   .
gi 1838138447 1875 E 1875
Cdd:TIGR02168  948 E 948
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2284-2765 1.09e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.51  E-value: 1.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2284 LEGYVAEKALLEESLQQKEVQEERLVEELEDLKVKLHQMQGLTAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGEREKA 2363
Cdd:PRK02224   208 LNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRER 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2364 LLAETERLTQDRLDLQRQaEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNED---LNQRVQALE---KQLKHDRQ 2437
Cdd:PRK02224   288 LEELEEERDDLLAEAGLD-DADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEaesLREDADDLEeraEELREEAA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2438 FIEEQAVEREHERDEFQQEIRSLEAQLRQ-TASVDNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAE-- 2514
Cdd:PRK02224   367 ELESELEEAREAVEDRREEIEELEEEIEElRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEae 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2515 --------------------------CNEEIDKLAGRIRELE---QALLNDAEGKRSISQLEQELHRSKLREQELSQDKQ 2565
Cdd:PRK02224   447 alleagkcpecgqpvegsphvetieeDRERVEELEAELEDLEeevEEVEERLERAEDLVEAEDRIERLEERREDLEELIA 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2566 ALEQQQLSNRLQISALQSKVDETRhCYHDNQREPTQELSDALDLAQQSLRSKEQEVEAV------VGQLETLQSELGLKE 2639
Cdd:PRK02224   527 ERRETIEEKRERAEELRERAAELE-AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELkeriesLERIRTLLAAIADAE 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2640 VELKHLALQLEQLTNQNA---DHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEEnfpSALIEEKNQEIDHLNAE 2716
Cdd:PRK02224   606 DEIERLREKREALAELNDerrERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQV---EEKLDELREERDDLQAE 682

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1838138447 2717 IQRLEQELDNTED----NKALEAE---LEDLRSQVEHLQSEVMRVRQDT-QEEVERL 2765
Cdd:PRK02224   683 IGAVENELEELEElrerREALENRveaLEALYDEAEELESMYGDLRAELrQRNVETL 739
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1716-2315 1.53e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 1.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1716 ERAALLNKERDTLDAKHKAQLDSLSASHRDQLTATAAELKSKH---SAELVALEAALDSKRKAdIESLEGVLKETnQAQL 1792
Cdd:COG1196    213 ERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELeelEAELAELEAELEELRLE-LEELELELEEA-QAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1793 EASEAELTRKHQEEKDELEMRmlgnmdtlestylkevQALRDEIIQLEERHcRGLNLQKSEHRQVLERHASEQLSIREEL 1872
Cdd:COG1196    291 YELLAELARLEQDIARLEERR----------------RELEERLEELEEEL-AELEEELEELEEELEELEEELEEAEEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1873 RKELAQLHIEKFSAMAVELSHVHKTELTAQKEALDTDHCKALETLKKQVLEVEQQHSLALQELSQTCTADKEQLLAQQQL 1952
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1953 qlqdlrgvsARELEACRRELEEESSRQRQHFLEEVELLKVQSEERLQDRINRLKTEFEEQKEARLEDLKRSFTSEQEEKE 2032
Cdd:COG1196    434 ---------EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2033 -RSYTDKMSQLTIQLQQLDTVVAQLRAEVGCLQGELEgkrsemETLDTLLQRRQRETQEGGNLLKMLTDDLQAGKEERRK 2111
Cdd:COG1196    505 gFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE------AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLP 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2112 LNQANE-KLKKVLIEMIRSTIATEDMIGQKICARAKTSEHGSHQRSSTGNEDAQESGISVADMSSQDMELTHLLCESLLV 2190
Cdd:COG1196    579 LDKIRArAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2191 SDTQINpGGEEAALNACSRLRHTVDTLLDLLNHANKQLEQTHGFHHSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKLK 2270
Cdd:COG1196    659 GGSLTG-GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1838138447 2271 SELQLEYhktEGLLEGYVAEKALLEESLQQKEVQEERLVEELEDL 2315
Cdd:COG1196    738 LEELLEE---EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 3486-3885 1.75e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.84  E-value: 1.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3486 RPTQTDHRVEGDWHGDRVDGQVESQLRAELEESQKQLKCAHDTQQEHKNKMQSVRVA--VAEGEEALRREQVRVQELQQQ 3563
Cdd:PTZ00121  1218 RKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAeeARKADELKKAEEKKKADEAKK 1297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3564 LEQERALSQRKDREKEERR-EALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLD---------- 3632
Cdd:PTZ00121  1298 AEEKKKADEAKKKAEEAKKaDEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaekkkeeak 1377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3633 ---DTQKELGDERQLSANQKELKLQDKTRLERLL-AEAESRLAEIHSTLAEAHRKVDEERERY--SRQVDELSRRHEada 3706
Cdd:PTZ00121  1378 kkaDAAKKKAEEKKKADEAKKKAEEDKKKADELKkAAAAKKKADEAKKKAEEKKKADEAKKKAeeAKKADEAKKKAE--- 1454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3707 trDRKFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRSkweeEDRARRAELQREKEAAIQQRVAVETLKEQKQetccA 3786
Cdd:PTZ00121  1455 --EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA----EEAKKKADEAKKAAEAKKKADEAKKAEEAKK----A 1524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3787 LEMERARSTQQGVELTELKEklhliKDKEREREEQWERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQElqh 3866
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEE-----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEE--- 1596

                          410
                   ....*....|....*....
gi 1838138447 3867 tLVELEREEKEMSAQRLRQ 3885
Cdd:PTZ00121  1597 -VMKLYEEEKKMKAEEAKK 1614
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 535-1350 2.24e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 2.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  535 EQQFEQTDLEKELLNQQCGELRDELLLKDRDLNVLREEVINTAEELEEARSRWGQVTEELRQALWELEEEKEKKRLAEEE 614
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  615 MNLKAHEQDNLKSK---LSALMEEREKEKAVLLTGKEAAEtsllvpaitpsEEEDElvgelKKKKQQDLLLSQQEIKqpa 691
Cdd:TIGR02168  318 LEELEAQLEELESKldeLAEELAELEEKLEELKEELESLE-----------AELEE-----LEAELEELESRLEELE--- 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  692 isaEQILELRDDkplqtlqVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNADH--------VNDLQEQIDALKAQ 763
Cdd:TIGR02168  379 ---EQLETLRSK-------VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELlkkleeaeLKELQAELEELEEE 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  764 CEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQtevdRLQGELEKSLDSLDTAEQVKSELESQIFC 843
Cdd:TIGR02168  449 LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE----RLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  844 LKQNLAKLEEAQAQTEQEREERRRKEEEMDDQIKKMEQVLEEELEQFESLLKAKDVELSEAKEKWEEESQEKETELLGVR 923
Cdd:TIGR02168  525 LSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  924 HHLEEQRREREEEVKALLEkQVLAVEEETERL----KTSHQQEI----KDLMERH--------RQEISELNTHLESEQLK 987
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLG-GVLVVDDLDNALelakKLRPGYRIvtldGDLVRPGgvitggsaKTNSSILERRREIEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  988 QQVNMEEEQKRQISFIKQVTEREHERMLSELSAKhNEELTQLRTEVSLE----LRESMEAAHQAELLQHQVQKRSELEAM 1063
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQL-RKELEELSRQISALrkdlARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1064 RLSLTnahvSQLEQESALTEAQGSPRDTFAQEIALLKAQHQAEldhIRQQEKLRELQQQPMNDLQQQWETLVAQERAAme 1143
Cdd:TIGR02168  763 IEELE----ERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL---REALDELRAELTLLNEEAANLRERLESLERRI-- 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1144 EEQAKDIQALRSQWDKNAESRESnlqmfLSEMQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQtsskdmnQELEA 1223
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIES-----LAAEIEELEELIEELESELEALLNERASLEEALALLRSEL-------EELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1224 ELEQACADRDAAARSLEELMSSHKAV---LQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEvgqLWTQLESMR 1300
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLelrLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1301 TSRQELGELkeQLLArsarVDDIERLKTEFNEQKREIKEQNEAeLESLRR 1350
Cdd:TIGR02168  979 NKIKELGPV--NLAA----IEEYEELKERYDFLTAQKEDLTEA-KETLEE 1021
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2539-3162 2.45e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.44  E-value: 2.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2539 GKRSISQ-LEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHcyhdnQREPTQELSDALDLAQQSLRSK 2617
Cdd:pfam15921   72 GKEHIERvLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQM-----ERDAMADIRRRESQSQEDLRNQ 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2618 EQEveaVVGQLETLQSelgLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEEN 2697
Cdd:pfam15921  147 LQN---TVHELEAAKC---LKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGS 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2698 FPSALIEEKNQEIDHLNAEIQRLEQeldntednkaleaELEDLRSQVEHLQSEVMRVRQDTQEEVERLHEVistlqaela 2777
Cdd:pfam15921  221 AISKILRELDTEISYLKGRIFPVED-------------QLEALKSESQNKIELLLQQHQDRIEQLISEHEV--------- 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2778 tlgpnlhEVSDSQDGDSINPSPAPSPEPDNYTVQEQARrgGANSLKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEG 2857
Cdd:pfam15921  279 -------EITGLTEKASSARSQANSIQSQLEIIQEQAR--NQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEK 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2858 LERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEG------------DAEERKLSEEvNDKV 2925
Cdd:pfam15921  350 QLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRlwdrdtgnsitiDHLRRELDDR-NMEV 428

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2926 Q-----------------NQEMSTLRDKNLHL---NSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTL--- 2982
Cdd:pfam15921  429 QrleallkamksecqgqmERQMAAIQGKNESLekvSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLqek 508

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2983 ERQVQEMRAELVDMEELVDEERIKIKTLKTVKGEL---SAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNER 3059
Cdd:pfam15921  509 ERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLrnvQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAM 588

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3060 EASQEEAQKEV------LTHAEVTLAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRA 3133
Cdd:pfam15921  589 QVEKAQLEKEIndrrleLQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668

                          650       660
                   ....*....|....*....|....*....
gi 1838138447 3134 LLNLETDNQRLKAQLRALQEDLAVQEEEL 3162
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEMETTTNKL 697
PTZ00121 PTZ00121
MAEBL; Provisional
 3501-3877 4.72e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 4.72e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3501 DRVDGQVESQLRAELEESQKQLKCAHDTQQEHKNKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERALSQRKDREK-- 3578
Cdd:PTZ00121  1345 AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEak 1424

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3579 ---EERREALHVSSE-QQRSEVMALKGLVEQERVAcSNLRRELQ----IEQSRSELLEKRLDDTQKELGDERQLSANQKE 3650
Cdd:PTZ00121  1425 kkaEEKKKADEAKKKaEEAKKADEAKKKAEEAKKA-EEAKKKAEeakkADEAKKKAEEAKKADEAKKKAEEAKKKADEAK 1503

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3651 LKLQDKTRLERLLAEAESRLAEiHSTLAEAHRKVDEERE-RYSRQVDELSRRHEADATRDRKFISDMRAQlEQERRQGEE 3729
Cdd:PTZ00121  1504 KAAEAKKKADEAKKAEEAKKAD-EAKKAEEAKKADEAKKaEEKKKADELKKAEELKKAEEKKKAEEAKKA-EEDKNMALR 1581

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3730 LAAVMNKLRAELLQSRSKWEEEDRARRAE-LQREKEAAI---------QQRVAVETLKEQKQETCCALEMERARSTQQGV 3799
Cdd:PTZ00121  1582 KAEEAKKAEEARIEEVMKLYEEEKKMKAEeAKKAEEAKIkaeelkkaeEEKKKVEQLKKKEAEEKKKAEELKKAEEENKI 1661

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3800 ELTELKEKLHliKDKEREREEQWERERRKGRQEQMERERRQERTNDKL--CELEMLRQQDQQRMQELQHTLV--ELEREE 3875
Cdd:PTZ00121  1662 KAAEEAKKAE--EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELkkKEAEEKKKAEELKKAEEENKIKaeEAKKEA 1739


                   ..
gi 1838138447 3876 KE 3877
Cdd:PTZ00121  1740 EE 1741
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 727-1484 5.48e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.22  E-value: 5.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  727 LKEVE--LKHLALQLEQlTNQNADHVNDLQE-QIDALKAQCEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTR 803
Cdd:TIGR02168  195 LNELErqLKSLERQAEK-AERYKELKAELRElELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  804 AQVVNVQTEVDRLQGELEKSLDSLDTAEQVKSELESQIFCLKQNLAKLEEAQAQTEQEREERRRKEEEMDDQIKKMEQVL 883
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  884 EEELEQFESLlKAKDVELSEAKEKWEEESQEKETELlgvrhhleeqrrereeevkALLEKQVLAVEEETERLKtSHQQEI 963
Cdd:TIGR02168  354 ESLEAELEEL-EAELEELESRLEELEEQLETLRSKV-------------------AQLELQIASLNNEIERLE-ARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  964 KDLMERHRQEISELNTHLESEQLKQqVNMEEEQKRQISFIKQVTEREHERMLSELSAKHnEELTQLRTEVSLELRESMEA 1043
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKE-LQAELEELEEELEELQEELERLEEALEELREEL-EEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1044 AHQAELLQHQVQKRSE------LEAMRLSLTNAHVSQL-----EQESALTEAQGSPRDTFA---QEIALLKAQHQAELDH 1109
Cdd:TIGR02168  491 LDSLERLQENLEGFSEgvkallKNQSGLSGILGVLSELisvdeGYEAAIEAALGGRLQAVVvenLNAAKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1110 IR------QQEKLRELQQQPMNDLQQQWETLVAqerAAMEEEQAKDIQALRSQWDKN---AESRESNLQMFLSEMQNSLT 1180
Cdd:TIGR02168  571 GRvtflplDSIKGTEIQGNDREILKNIEGFLGV---AKDLVKFDPKLRKALSYLLGGvlvVDDLDNALELAKKLRPGYRI 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1181 ATQTDLTQTLKALSQTQAELQRSG--AKLQELQTSSKDMN--QELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQ 1256
Cdd:TIGR02168  648 VTLDGDLVRPGGVITGGSAKTNSSilERRREIEELEEKIEelEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1257 ALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLESMRTSRQELGELKEQLLARSARvddIERLKTEFNEQKRE 1336
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ---IEQLKEELKALREA 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1337 IKEQNeAELESLRRYFeQRLRATEEGHREEIALLQLRLvERALEESVIRTADDSFSSISQGQAEEEKDhlfsdavfKLEK 1416
Cdd:TIGR02168  805 LDELR-AELTLLNEEA-ANLRERLESLERRIAATERRL-EDLEEQIEELSEDIESLAAEIEELEELIE--------ELES 873

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1417 HKEALDNVSLQLEEKHSMDLSYLQSSMslsfkEELQQVQSDITD--QYYEELQELKTRHAMELEKLRAKL 1484
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELS-----EELRELESKRSElrRELEELREKLAQLELRLEGLEVRI 938
PTZ00121 PTZ00121
MAEBL; Provisional
 2812-3148 7.30e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 7.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2812 EQARRGGANSLKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEGLErllLTQEEEYRGHGEEFGKrlTAEREKADKLQ 2891
Cdd:PTZ00121  1454 EEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADE---AKKAAEAKKKADEAKK--AEEAKKADEAK 1528

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2892 SVLTLKEAElDEVKAQKEGDAEERKLSEEVN--DKVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEmDTLKTKEQEME 2969
Cdd:PTZ00121  1529 KAEEAKKAD-EAKKAEEKKKADELKKAEELKkaEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIE-EVMKLYEEEKK 1606

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2970 METEVLR---ETSLTLE--RQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATS 3044
Cdd:PTZ00121  1607 MKAEEAKkaeEAKIKAEelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED 1686

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3045 MRACIQELTVQLNEREASQEEAQKEVLTHAEVTLAKADAALRQREAELARLRAEHQALKAELTEVKQG----LSTSTERA 3120
Cdd:PTZ00121  1687 EKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEekkkIAHLKKEE 1766

                          330       340
                   ....*....|....*....|....*...
gi 1838138447 3121 EKLHEEGQTKDRALLNLETDNQRLKAQL 3148
Cdd:PTZ00121  1767 EKKAEEIRKEKEAVIEEELDEEDEKRRM 1794
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 121-394 7.88e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 7.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  121 KEQLKQLQEAVEKRNEIIARLSSNLQEALASRDQVQLEAQSLAGQIQGLQRQLQQTSVEFLRIKSQSGAEVLNTRQphgR 200
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE---L 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  201 CSQDADLNHKEApsgsaapetiscvegfstdtALEKLRVELEEERKNSQRIYAELALEMEKHQHVLSLLEKEKNSREEEQ 280
Cdd:COG1196    315 EERLEELEEELA--------------------ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  281 KEKEEQLQDLQMQFSLVQTQCLEMQQYKEEKEKLNREVLELRKRLQEEADAERRLGEEVASSALRLQRQEEEMLRLKEEH 360
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1838138447  361 REEVEGVRQLLEEREKELKFREEEVLGLKASKNR 394
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAE 488
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3534-3810 8.86e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 8.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3534 NKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERalsqRKDREKEERREALHVSSEQQRSEVMALKGLVEQERVACSNL 3613
Cdd:TIGR02168  670 SSILERRREIEELEEKIEELEEKIAELEKALAELR----KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3614 RRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKElklqDKTRLERLLAEAESRLAEIHSTLAEAHRKVDEERERYSR 3693
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA----EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3694 QVDELsRRHEADATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAELlqsrskweEEDRARRAELQREKEAAIQQRVAV 3773
Cdd:TIGR02168  822 LRERL-ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI--------EELESELEALLNERASLEEALALL 892

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1838138447 3774 ETLKEQKQETCCALEMERARSTQQGVELTELKEKLHL 3810
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLEL 929
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 554-1331 1.03e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  554 ELRD-ELLLKDRDLNVLREEVINTAEELEEARSRWGQVTEELRQALWELEEEKEKKRLAEEEMNLKAHEQDNLKSKLSAL 632
Cdd:TIGR02168  221 ELRElELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  633 meerEKEKAVLLTGKEAAETSLlvpaitpsEEEDELVGELKKKKQQDLLLSQQEIKQPAISAEQILELRDDKPLQTLQVE 712
Cdd:TIGR02168  301 ----EQQKQILRERLANLERQL--------EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  713 AMVGQLETLQSELGLKEVELKHLALQLEQLTNQ---NADHVNDLQEQIDALKAQCEHLLLHLEEmttthkttaALIDEKT 789
Cdd:TIGR02168  369 ELESRLEELEEQLETLRSKVAQLELQIASLNNEierLEARLERLEDRRERLQQEIEELLKKLEE---------AELKELQ 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  790 TELDRTSKELERTRAQVVNVQTEVDRLQGELEKSLDSLDTAEQVKSELESQIFCLK---QNLAKLEEAQAQTEQEREERR 866
Cdd:TIGR02168  440 AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLErlqENLEGFSEGVKALLKNQSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  867 RKEEEMDDQIKK-------------------MEQVLEEELEQFESLLKAK---------DVELSEAKEKWEEESQEKETE 918
Cdd:TIGR02168  520 GILGVLSELISVdegyeaaieaalggrlqavVVENLNAAKKAIAFLKQNElgrvtflplDSIKGTEIQGNDREILKNIEG 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  919 LLGVRHHLEEQRREREEEVKALLEkQVLAVEEETERL----KTSHQQEI----KDLMERH--------RQEISELNTHLE 982
Cdd:TIGR02168  600 FLGVAKDLVKFDPKLRKALSYLLG-GVLVVDDLDNALelakKLRPGYRIvtldGDLVRPGgvitggsaKTNSSILERRRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  983 SEQLKQQVNMEEEQKRQISFIKQVTEREHERMLSELSAKH------NEELTQLRTEVSLELRESMEAAHQAELLQHQV-- 1054
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRkeleelSRQISALRKDLARLEAEVEQLEERIAQLSKELte 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1055 -QKRSELEAMRLSLTNAHVSQLEQESALTEAQ----GSPRDTFAQEIALLKAQHQAELDHIRQQEKLRELQQQPMNDLQQ 1129
Cdd:TIGR02168  759 lEAEIEELEERLEEAEEELAEAEAEIEELEAQieqlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1130 QWETLvAQERAAMEEEQAKDIQALRSQWDKNAESRESnlqmfLSEMQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQE 1209
Cdd:TIGR02168  839 RLEDL-EEQIEELSEDIESLAAEIEELEELIEELESE-----LEALLNERASLEEALALLRSELEELSEELRELESKRSE 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1210 LQTSSKDMNQELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKK---NSE 1286
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnlAAI 992

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1838138447 1287 QEVGQLWTQLESMRTSRQELGELKEQLLARSARVDDI--ERLKTEFN 1331
Cdd:TIGR02168  993 EEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREarERFKDTFD 1039
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1464-2125 1.08e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 1.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1464 EELQELKTrhamELEKLRAKLSDHHVKELtRAHLEAARQVEVEVEQRMWCLTEELQSRMTIIHTLDSKLAALSKQHDAEV 1543
Cdd:TIGR02168  213 ERYKELKA----ELRELELALLVLRLEEL-REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1544 QR--NTQKLKQEFAGELVHLEEALKQ---EREDVQEERKRWREELQEKhQAELSALRSELDR------EMESERTRLEKE 1612
Cdd:TIGR02168  288 KElyALANEISRLEQQKQILRERLANlerQLEELEAQLEELESKLDEL-AEELAELEEKLEElkeeleSLEAELEELEAE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1613 LHEEKERLKTLQAALDNDESPQVLIVRQrlEAQYDGELQRAKScmatEVKELTARLQEQGEERLHQAQERLHGEKAALEQ 1692
Cdd:TIGR02168  367 LEELESRLEELEEQLETLRSKVAQLELQ--IASLNNEIERLEA----RLERLEDRRERLQQEIEELLKKLEEAELKELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1693 SLAQKYE--ASLAELKSKHQSELEHERAALLNKERDTLDAK-----HKAQLDSLSASHRDQLTATAAELKSKHSAELVAL 1765
Cdd:TIGR02168  441 ELEELEEelEELQEELERLEEALEELREELEEAEQALDAAErelaqLQARLDSLERLQENLEGFSEGVKALLKNQSGLSG 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1766 EAAL-------DSKRKADIE-----SLEGVLKETNQAQLEASEAEltrkhqeEKDELEMRMLGNMDTLESTYLKEVQALR 1833
Cdd:TIGR02168  521 ILGVlselisvDEGYEAAIEaalggRLQAVVVENLNAAKKAIAFL-------KQNELGRVTFLPLDSIKGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1834 DEIIQLEERHCRGLNLQKSEHRQVLErHASEQLSIREELRKELAQLHIEKFSAMAVEL------SHVHKTELTAQKEALD 1907
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFDPKLRKALS-YLLGGVLVVDDLDNALELAKKLRPGYRIVTLdgdlvrPGGVITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1908 TDHCKALETLKKQVLEVEQQHSL---ALQELSQTCTADKEQLLAQQQLQLQDLRGVSARELEACRRELEEESSRQRQhfl 1984
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAElekALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI--- 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1985 eevellkvqseerlqDRINRLKTEFEEQKEARLEDLKRSFT--SEQEEKERSYTDKMSQLTIQLQQLDTVVAQLRAEVGC 2062
Cdd:TIGR02168  750 ---------------AQLSKELTELEAEIEELEERLEEAEEelAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1838138447 2063 LQGELEGKRSEMETLDTLLQRRQRETQEGGNLLKMLTDDLQAGKEERRKLNQANEKLKKVLIE 2125
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA 877
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1308-2119 1.14e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 1.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1308 ELKEQL--LARSARVDDIERLKTEFNEQKREIKEQNEaeleslrryfeQRLRATEEGHREEIALLQLRLVERALEESvIR 1385
Cdd:TIGR02168  217 ELKAELreLELALLVLRLEELREELEELQEELKEAEE-----------ELEELTAELQELEEKLEELRLEVSELEEE-IE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1386 TADDSFSSISQGQAEEEKDhlfsdavfkLEKHKEALDNVSLQLEEKHSMDLSYLQSSMSLSFKEELQQVQSDITDQYYEE 1465
Cdd:TIGR02168  285 ELQKELYALANEISRLEQQ---------KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1466 LQELKTRHAMELEKLRAKLSDhhvkelTRAHLEAARQVEVEVEQRMWCLTEELQSrmtiihtLDSKLAALskqhdaevQR 1545
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEE------LEEQLETLRSKVAQLELQIASLNNEIER-------LEARLERL--------ED 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1546 NTQKLKQEFAGELVHLEEALKQEREDVQEERKRWREELQEKH---QAELSALRSELdREMESERTRLEKELHEEKERLKT 1622
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELerlEEALEELREEL-EEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1623 LQAALDNDESPQVLIVRQRLEA-QYDGELQRAKSCMATEvKELTARLQEQGEERLHQA----QERLHGEKAALEQSLAQK 1697
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNQsGLSGILGVLSELISVD-EGYEAAIEAALGGRLQAVvvenLNAAKKAIAFLKQNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1698 yeASLAELKSKHQSELEHERAALLN---------KERDTLDAKHKAQLDSLSASHR---DQLTATAAELKSKHSAELVAL 1765
Cdd:TIGR02168  573 --VTFLPLDSIKGTEIQGNDREILKniegflgvaKDLVKFDPKLRKALSYLLGGVLvvdDLDNALELAKKLRPGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1766 EAALDSKR----KADIESLEGVL-KETNQAQLEASEAELTRKHQEEKDELEmrmlgnmdtlesTYLKEVQALRDEIIQLE 1840
Cdd:TIGR02168  651 DGDLVRPGgvitGGSAKTNSSILeRRREIEELEEKIEELEEKIAELEKALA------------ELRKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1841 ERHcRGLNLQKSEHRQVLERHASEQlsirEELRKELAQLHIEKFSAMAVELSHVHKTELTAQKEALDTDHCKALETLKKQ 1920
Cdd:TIGR02168  719 KEL-EELSRQISALRKDLARLEAEV----EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1921 VLEVEQQHSLALQELSQTCTADKEQLLAQQQLQLQDLRGVSARELEACRRELEEESSRQRQHFLEEVELLKVQSEERLQD 2000
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2001 RINRLKTEFEEQKEARleDLKRSFTSEQEEKERSYTDKMSQLTIQLQQLDTVVAQLRAEVGCLQGELegkrseMETLDTL 2080
Cdd:TIGR02168  874 ELEALLNERASLEEAL--ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI------DNLQERL 945

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1838138447 2081 LQRRQRETQEGGNLLKMLTDDLQAGKEERRKLNQANEKL 2119
Cdd:TIGR02168  946 SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
mukB PRK04863
chromosome partition protein MukB;
2325-2653 1.44e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 54.96  E-value: 1.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2325 LTAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGERekalLAeterltqdrLDLQRQAEKDHKSLSLRLRALERDLEEKE 2404
Cdd:PRK04863   791 LRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSH----LA---------VAFEADPEAELRQLNRRRVELERALADHE 857

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2405 TQdletEQHHKTHNEDLNQRVQALEKQLKHDRQFieeqaverehERDEFQQEIRSLEAQLRQTASVDNKGHRFQDLVLQV 2484
Cdd:PRK04863   858 SQ----EQQQRSQLEQAKEGLSALNRLLPRLNLL----------ADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQL 923

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2485 ESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSKLR--EQELSQ 2562
Cdd:PRK04863   924 EPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLEqaEQERTR 1003

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2563 DKQALEQQQlsNRL-QISALQSKVDETRHCYHDNQREPTQELSD----ALDLAQQSLRSKEQEVEAVV----GQLETLQS 2633
Cdd:PRK04863  1004 AREQLRQAQ--AQLaQYNQVLASLKSSYDAKRQMLQELKQELQDlgvpADSGAEERARARRDELHARLsanrSRRNQLEK 1081

                          330       340
                   ....*....|....*....|
gi 1838138447 2634 ELGLKEVELKHLALQLEQLT 2653
Cdd:PRK04863  1082 QLTFCEAEMDNLTKKLRKLE 1101
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2948-3163 1.70e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 1.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2948 QKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRR 3027
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3028 EGKLQEEIENLRQEATSMRAcIQELTVQLNEREASQEEAQKEVLTHAEVTLAKADAALRQREAELARLRAEHQALKAELT 3107
Cdd:COG4942     99 LEAQKEELAELLRALYRLGR-QPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1838138447 3108 EVKQGLSTSTERAEKLHEEgqtKDRALLNLETDNQRLKAQLRALQEDLAVQEEELA 3163
Cdd:COG4942    178 ALLAELEEERAALEALKAE---RQKLLARLEKELAELAAELAELQQEAEELEALIA 230
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1425-2121 1.98e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.46  E-value: 1.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1425 SLQLEEKHSMDLSYLQSSMSLSFKEELQQVQSDItDQYYEELQELKTRHAMELEKLRAKLSDHHvKELTRAHLEAARQVE 1504
Cdd:pfam12128  259 RLSHLHFGYKSDETLIASRQEERQETSAELNQLL-RTLDDQWKEKRDELNGELSAADAAVAKDR-SELEALEDQHGAFLD 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1505 VEVEQRMWCLtEELQSRMTIIHTLDSKLAALSKQHDaEVQRNTQKLKQEFAGELVHLEEALKQEREDVQEERKRWREELQ 1584
Cdd:pfam12128  337 ADIETAAADQ-EQLPSWQSELENLEERLKALTGKHQ-DVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAE 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1585 EKHQAELSALRSELD---REMESERTRLEKELHEEKERLKtlQAALDNDESPQVLIVRQRLEAQYDGELQRAKSCMATEV 1661
Cdd:pfam12128  415 DDLQALESELREQLEagkLEFNEEEYRLKSRLGELKLRLN--QATATPELLLQLENFDERIERAREEQEAANAEVERLQS 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1662 KELTAR-LQEQGEERLHQAQERLHGEKAALEQSLAQKYEA--SLAELKSKHQSELEHERAALLNKE---RDTLDakhkAQ 1735
Cdd:pfam12128  493 ELRQARkRRDQASEALRQASRRLEERQSALDELELQLFPQagTLLHFLRKEAPDWEQSIGKVISPEllhRTDLD----PE 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1736 LDSLSASHRDQLTATAAELKSKHSAELVALEAALDSKRkadiesleGVLKETNQAQLEASEAeltrkhQEEKDELEMRML 1815
Cdd:pfam12128  569 VWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERL--------DKAEEALQSAREKQAA------AEEQLVQANGEL 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1816 GNMDTLESTYLKEVQALRDEIIQLEerhcrglNLQKSEHRQVLERHASEQLSIREELRKelaqlhiekfsamavelshvh 1895
Cdd:pfam12128  635 EKASREETFARTALKNARLDLRRLF-------DEKQSEKDKKNKALAERKDSANERLNS--------------------- 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1896 kteLTAQKEALDTDHCKALETLKKQVLEveqqHSLALQELSQTCTADKEQLLAQQQLQLQDLRGVSARELEACRRELEEE 1975
Cdd:pfam12128  687 ---LEAQLKQLDKKHQAWLEEQKEQKRE----ARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRD 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1976 -------------SSRQRQHFLEEVELLKVQSEERLQDRinRLKTEFEEQKEARLEDLKRSFTSEQEEKERSYTDKMSQL 2042
Cdd:pfam12128  760 laslgvdpdviakLKREIRTLERKIERIAVRRQEVLRYF--DWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADT 837

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1838138447 2043 TIQLQQLDTVVAQLRAEVGCLQGELEGKRSEMETLDTLlqrrqRETQEGGNLLKMLTDDLQAGKEERRKLNQANEKLKK 2121
Cdd:pfam12128  838 KLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATL-----KEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKK 911
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 691-1487 3.80e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 3.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  691 AISAEQILELRDDKPLQTLQVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNAD---HVNDLQEQIDALKAQCEHL 767
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEElqkELYALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  768 LLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDRLQGELEKSLDSLDTAEQVKSELESQIFCLKQN 847
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  848 LAKLEEAQAQTEQEREERRRKEEEMDDQIKKMEQVLEEELEQFESLLKAKDVELSEAKEKweeesqeketellgvrhhLE 927
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEE------------------EL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  928 EQRREREEEVKALLEKQVLAVEEETERLktshqQEIKDLMERHRQEISELNTHLES-EQLKQQVNMEEEQKRQISFIKQV 1006
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQAL-----DAAERELAQLQARLDSLERLQENlEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1007 terehermLSELSAKHNEeltqLRTEVSLELRESMEA----------AHQAELLQHQVQKRSELEAMRLSLTNAHVSQLE 1076
Cdd:TIGR02168  525 --------LSELISVDEG----YEAAIEAALGGRLQAvvvenlnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1077 QESALTEAQGSPRDTFAQEIALLKAQhQAELDHIRQQEKLRE-LQQQPMNDLQQQWETLvaqeraameeeqakDIQALRS 1155
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRKAL-SYLLGGVLVVDDLDNaLELAKKLRPGYRIVTL--------------DGDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1156 QWDKNAESRESNLQMF-----LSEMQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQTSSKDMNQELeAELEQACA 1230
Cdd:TIGR02168  658 GGVITGGSAKTNSSILerrreIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI-SALRKDLA 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1231 DRDAAARSLEELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLESMRTSRQELGELK 1310
Cdd:TIGR02168  737 RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLN 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1311 EQLLARSARVDDIER---LKTEFNEQKREIKEQNEAELESLrryfEQRLRATEEGHREEIALLQLRLVERALEESVIRTA 1387
Cdd:TIGR02168  817 EEAANLRERLESLERriaATERRLEDLEEQIEELSEDIESL----AAEIEELEELIEELESELEALLNERASLEEALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1388 DDSFSSISQGQAEEEKDhlFSDAVFKLEKHKEALDNVSLQLEEkhsmdlsylqssmslsFKEELQQVQSDITDQYYEELQ 1467
Cdd:TIGR02168  893 RSELEELSEELRELESK--RSELRRELEELREKLAQLELRLEG----------------LEVRIDNLQERLSEEYSLTLE 954

                          810       820
                   ....*....|....*....|...
gi 1838138447 1468 ELKTRHA---MELEKLRAKLSDH 1487
Cdd:TIGR02168  955 EAEALENkieDDEEEARRRLKRL 977
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2704-3162 4.65e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 4.65e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2704 EEKNQEIDHLNAEIQRLEQELDNTEDNK-ALEAELEDLRSQVEHLQSEVMRVRQDT---QEEVERLHEVISTLQAELATL 2779
Cdd:PRK02224   247 EERREELETLEAEIEDLRETIAETEREReELAEEVRDLRERLEELEEERDDLLAEAgldDADAEAVEARREELEDRDEEL 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2780 GPNLHEVSdsqdgdsinpspapspepdnytVQEQARRGGANSLKqELSLSYSASSHSLRSRFKTLQSQLEAAAA------ 2853
Cdd:PRK02224   327 RDRLEECR----------------------VAAQAHNEEAESLR-EDADDLEERAEELREEAAELESELEEAREavedrr 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2854 -EKEGLERLLLTQEEEYRGHGEEFGK---RLTAEREKADKLQSVLTLKEAELDEVK---AQKEGDAEERKLSE---EVND 2923
Cdd:PRK02224   384 eEIEELEEEIEELRERFGDAPVDLGNaedFLEELREERDELREREAELEATLRTARervEEAEALLEAGKCPEcgqPVEG 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2924 KVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKeQEMEMETEVLRETSLTLERQVQEMRAELvdmeelvDEE 3003
Cdd:PRK02224   464 SPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDL-VEAEDRIERLEERREDLEELIAERRETI-------EEK 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3004 RIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLN------EREASQEEAQKEVLTHAEVT 3077
Cdd:PRK02224   536 RERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIEslerirTLLAAIADAEDEIERLREKR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3078 LAKADAAlRQREAELARLRAEHQALKAELTEvkqglststERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDLAV 3157
Cdd:PRK02224   616 EALAELN-DERRERLAEKRERKRELEAEFDE---------ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGA 685


                   ....*
gi 1838138447 3158 QEEEL 3162
Cdd:PRK02224   686 VENEL 690
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 559-1129 4.79e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 4.79e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  559 LLLKDRDLNVLREEVINTAEELEEARsrwgqvtEELRQALWELEEEKEKKRLAEEEMNLKAHEQDNLKSKLSALMEEREK 638
Cdd:COG1196    230 LLLKLRELEAELEELEAELEELEAEL-------EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  639 EKAVLLTGKEAAEtsllvpaitpsEEEDELVGELKKKKQQDLLLSQQEIKQpAISAEQILELRDDKPLQTLQVEAMVGQL 718
Cdd:COG1196    303 DIARLEERRRELE-----------ERLEELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  719 ETLQSELGLKEVELKHLALQLEQLTNQNADHVNDLQEQIDALKAQCEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKE 798
Cdd:COG1196    371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  799 LERTRAQVVNVQTEVDRLQGELEKSLDSLDTAEQVKSELESQIFCLKQNLAKLE--EAQAQTEQEREERRRKEEEMDDQI 876
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgfLEGVKAALLLAGLRGLAGAVAVLI 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  877 KKMEQVLEEELEQFESLLKAKDVELSEA--------KEKWEEESQEKETELLGVRHHLEEQRREREEEVKALLEKQVLAV 948
Cdd:COG1196    531 GVEAAYEAALEAALAAALQNIVVEDDEVaaaaieylKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  949 EEETERLKTSHQQEIKDLMERHRQEISELNTHLESEQLK-------QQVNMEEEQKRQISFIKQVTEREHERMLSELSAK 1021
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1022 HNEELTQLRTEVSLELRESMEAAHQAELLQHQVQKRSELEAMRLSLTNAHVSQLEQESALTEAQGSP----RDTFAQEIA 1097
Cdd:COG1196    691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPeppdLEELERELE 770

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1838138447 1098 LLKAQ--------HQAELDHIRQQEKLRELQQQpMNDLQQ 1129
Cdd:COG1196    771 RLEREiealgpvnLLAIEEYEELEERYDFLSEQ-REDLEE 809
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2984-3163 5.17e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 5.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2984 RQVQEMRAELVDMEELVDEERIKIKTLKTVKgelsaeretlrrregKLQEEIENLRQEATSMRACIQELTVQLNEREAsq 3063
Cdd:COG4913    228 DALVEHFDDLERAHEALEDAREQIELLEPIR---------------ELAERYAAARERLAELEYLRAALRLWFAQRRL-- 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3064 eEAQKEVLTHAEVTLAKADAALRQREAELARLRAEHQALKAELTEVkqglstSTERAEKLHEEGQTKDRALLNLETDNQR 3143
Cdd:COG4913    291 -ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGN------GGDRLEQLEREIERLERELEERERRRAR 363

                          170       180
                   ....*....|....*....|
gi 1838138447 3144 LKAQLRALQEDLAVQEEELA 3163
Cdd:COG4913    364 LEALLAALGLPLPASAEEFA 383
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1972-2677 6.02e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.92  E-value: 6.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1972 LEEESSRQR-QHFLEEVELLKVQSEERlqDRINRLKTEFEEQKEARLE---------DLKRSFTSEQEEKERSYTDKMSQ 2041
Cdd:pfam12128  214 PKSRLNRQQvEHWIRDIQAIAGIMKIR--PEFTKLQQEFNTLESAELRlshlhfgykSDETLIASRQEERQETSAELNQL 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2042 LTIQLQQLDTVVAQLRAEVGCLQGELEGKRSEMETLDTLLQRRQRETQEggnllkMLTDDLQAGKEERRKLNQANEKLKk 2121
Cdd:pfam12128  292 LRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIE------TAAADQEQLPSWQSELENLEERLK- 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2122 VLIEMIRSTIATEDMIGQKICARAKTSEHGSHQRSSTGNEdAQESGISVADMSSQDMEltHLLCESLLVSDTQINPGGEE 2201
Cdd:pfam12128  365 ALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIRE-ARDRQLAVAEDDLQALE--SELREQLEAGKLEFNEEEYR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2202 AALNA------CSRLRHTVDTLLDL------LNHANKQLEQTHGFHHSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKL 2269
Cdd:pfam12128  442 LKSRLgelklrLNQATATPELLLQLenfderIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSA 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2270 KSELQ----------LEYHKTEGLL----EGYVAEKALLEESLQQKEVQEERLVEELEDLKVKLH----QMQGLTAELDG 2331
Cdd:pfam12128  522 LDELElqlfpqagtlLHFLRKEAPDweqsIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDlkriDVPEWAASEEE 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2332 LRLKHQELSE----EHSLLLRQKEHLSAGLGEREKALLAET--------ERLTQDRLDLQRQAEKDHKSlslRLRALERD 2399
Cdd:pfam12128  602 LRERLDKAEEalqsAREKQAAAEEQLVQANGELEKASREETfartalknARLDLRRLFDEKQSEKDKKN---KALAERKD 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2400 LEEKETQDLETEQhhkthnedlnqrvQALEKQLKHDRQFIEEQAVEREHERDEFQQEIrsLEAQLRQTASVDnkghrfqd 2479
Cdd:pfam12128  679 SANERLNSLEAQL-------------KQLDKKHQAWLEEQKEQKREARTEKQAYWQVV--EGALDAQLALLK-------- 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2480 lvlqveslQAIIKDKTEDHDSLIAANQQAQRDLAECN---EEIDKLAGRIRELEQALLNDAEGKRSISQLEQEL-HRSKL 2555
Cdd:pfam12128  736 --------AAIAARRSGAKAELKALETWYKRDLASLGvdpDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYqETWLQ 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2556 REQELSQDKQALEQQQLSNRLQISALQSKVdETRHCYHDNQREptqELSDALDLAQQSLRSKEQEVEAVVGQLETLQSEL 2635
Cdd:pfam12128  808 RRPRLATQLSNIERAISELQQQLARLIADT-KLRRAKLEMERK---ASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQ 883

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1838138447 2636 GlkEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSAL 2677
Cdd:pfam12128  884 A--QGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADH 923
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2492-3150 7.66e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 7.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2492 KDKTEDHDSLIAANQQaqrdLAECNEEIDKLAGrirELEQAllndaegKRSISQLEQELHRSKLREQELSQDKQALEQQQ 2571
Cdd:PRK02224   199 KEEKDLHERLNGLESE----LAELDEEIERYEE---QREQA-------RETRDEADEVLEEHEERREELETLEAEIEDLR 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2572 LSnrlqISALQSKVDETRHCYHDnQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQ 2651
Cdd:PRK02224   265 ET----IAETEREREELAEEVRD-LRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQA 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2652 LTNQnadhvnelqeqIDALKENVSALAILNEEREEQSEAEEPEEENFPSAlIEEKNQEIDHLNAEIQRLEQELDNTE-DN 2730
Cdd:PRK02224   340 HNEE-----------AESLREDADDLEERAEELREEAAELESELEEAREA-VEDRREEIEELEEEIEELRERFGDAPvDL 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2731 KALEAELEDLRsqvehlqsevmrvrqdtqEEVERLHEVISTLQAELATLgpnlhevsdsqdgdsinpspapspepdnytv 2810
Cdd:PRK02224   408 GNAEDFLEELR------------------EERDELREREAELEATLRTA------------------------------- 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2811 qeqarrgganslkqelslsysasshslRSRFKTLQSQLEAAAAEKEGlerllltQEEEYRGHGEEFGKRltaeREKADKL 2890
Cdd:PRK02224   439 ---------------------------RERVEEAEALLEAGKCPECG-------QPVEGSPHVETIEED----RERVEEL 480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2891 qsvltlkEAELDEVKAQKEgdAEERKLSEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEM 2970
Cdd:PRK02224   481 -------EAELEDLEEEVE--EVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEA 551

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2971 ETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKgELSAERETLRRREGKLQEEIENLRQEATSMRACIQ 3050
Cdd:PRK02224   552 EAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLA 630

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3051 ELTVQLNEREASQEEAQ----KEVLTHAEVTLAKADAALRQREAELARLRAEHQALKAELTEVKQ------GLSTSTERA 3120
Cdd:PRK02224   631 EKRERKRELEAEFDEARieeaREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEElrerreALENRVEAL 710

                          650       660       670
                   ....*....|....*....|....*....|
gi 1838138447 3121 EKLHEEGQTkdrallnLETDNQRLKAQLRA 3150
Cdd:PRK02224   711 EALYDEAEE-------LESMYGDLRAELRQ 733
PTZ00121 PTZ00121
MAEBL; Provisional
 2361-3036 9.51e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 9.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2361 EKALLAETERLTQD--RLDLQRQAEKDHKSLSLRLRALERDLEE--KETQDLETEQHHKTHNEDLNQRVQALEkQLKHDR 2436
Cdd:PTZ00121  1161 EDARKAEEARKAEDakKAEAARKAEEVRKAEELRKAEDARKAEAarKAEEERKAEEARKAEDAKKAEAVKKAE-EAKKDA 1239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2437 QFIEEQAVEREHERDEFQQEIRSLEAQLRQTASVDNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRdlAECN 2516
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE--AKKA 1317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2517 EEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSKLREQELSQDK-QALEQQQLSNRLQISALQSKVDETRHCyhDN 2595
Cdd:PTZ00121  1318 DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKaEAAEKKKEEAKKKADAAKKKAEEKKKA--DE 1395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2596 QREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQL-----EQLTNQNADHVNELQEQIDAL 2670
Cdd:PTZ00121  1396 AKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAkkkaeEAKKAEEAKKKAEEAKKADEA 1475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2671 KENVSALAILNEEREEQSEAEEPEEENFPSAliEEKNQEIDHLNAEIQRLEQELDNTEDNKaleaELEDLRSQVEHLQSE 2750
Cdd:PTZ00121  1476 KKKAEEAKKADEAKKKAEEAKKKADEAKKAA--EAKKKADEAKKAEEAKKADEAKKAEEAK----KADEAKKAEEKKKAD 1549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2751 VMRvrqdTQEEVERLHEVISTLQAELATLGPNLhevsdsqdgdsinpspapspepdnytvqeQARRggANSLKQELSLSY 2830
Cdd:PTZ00121  1550 ELK----KAEELKKAEEKKKAEEAKKAEEDKNM-----------------------------ALRK--AEEAKKAEEARI 1594

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2831 SASSHSLRSRFKTLQSQLEAAAAEKEGLERLllTQEEEYRGHGEEFGKRLTAEREKADKLQsvltlKEAELDEVKAQKEG 2910
Cdd:PTZ00121  1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL--KKAEEEKKKVEQLKKKEAEEKKKAEELK-----KAEEENKIKAAEEA 1667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2911 --DAEERKLSEEVNDKVQNQEMStlrdknlhlnsliAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQE 2988
Cdd:PTZ00121  1668 kkAEEDKKKAEEAKKAEEDEKKA-------------AEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEE 1734

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1838138447 2989 MRAELVD----MEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIE 3036
Cdd:PTZ00121  1735 AKKEAEEdkkkAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1240-2022 1.01e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1240 EELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLESMRtsrQELGELKEQLLARSAR 1319
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELE---EEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1320 VDDIERLKTEFNEQKREIKEQNEAELESLRRYFEQRLRATEEGHREEIALLQLRLVERALEESVIRTADDSFSSISQGQA 1399
Cdd:TIGR02168  297 ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1400 EEEKDHLFSDAVFKLEKHKEALDNVSLQLEEKhsmdLSYLQSSMSlSFKEELQQVQSDITDQYYEELQELKTRHAMELEK 1479
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEAR----LERLEDRRE-RLQQEIEELLKKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1480 LRAKLSDHhvkeltRAHLEAARQVEVEVEQRMWCLTEELQSRMTIIHTLDSKLAALSKQHD--AEVQRNTQKLKQEF--A 1555
Cdd:TIGR02168  452 LQEELERL------EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEgvKALLKNQSGLSGILgvL 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1556 GELVHLEEALKQEREDVQEER---------KRWREELQ-----EKHQAELSALRSELDREMESERTRLEKELHEEKERL- 1620
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRlqavvvenlNAAKKAIAflkqnELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAk 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1621 ----------KTLQAALDN----DESPQVLIVRQRLEAQY-----DGELQRAKSCMATEVKELTARLQEQGEERlhqaqE 1681
Cdd:TIGR02168  606 dlvkfdpklrKALSYLLGGvlvvDDLDNALELAKKLRPGYrivtlDGDLVRPGGVITGGSAKTNSSILERRREI-----E 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1682 RLHGEKAALEQSLAQKyEASLAELKSKhQSELEHERAALLNKERDTLDAKHKAQLDSLSASHRDQLTATAAELKSKHSAE 1761
Cdd:TIGR02168  681 ELEEKIEELEEKIAEL-EKALAELRKE-LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1762 LVALEAALDSKRkaDIESLEGVLKETNQAQLEASEAELTRKHQEEKDELemrmlgnmDTLEstylKEVQALRDEIIQLEE 1841
Cdd:TIGR02168  759 LEAEIEELEERL--EEAEEELAEAEAEIEELEAQIEQLKEELKALREAL--------DELR----AELTLLNEEAANLRE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1842 RhCRGLNLQKSEHRQVLERhaSEQLSIREELRKELAQLHIEKFSAMAVELS--HVHKTELTAQKEALDTDHCKALETLKK 1919
Cdd:TIGR02168  825 R-LESLERRIAATERRLED--LEEQIEELSEDIESLAAEIEELEELIEELEseLEALLNERASLEEALALLRSELEELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1920 QVLEVEQQHSlALQELSQTCTADKEQLLAQQQLQLQDLRGVSARELEACRRELEEessrqrqhfLEEVELLKVQSEERLQ 1999
Cdd:TIGR02168  902 ELRELESKRS-ELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEE---------AEALENKIEDDEEEAR 971

                          810       820       830
                   ....*....|....*....|....*....|....*..
gi 1838138447 2000 DRINRLKT--------------EFEEQKEaRLEDLKR 2022
Cdd:TIGR02168  972 RRLKRLENkikelgpvnlaaieEYEELKE-RYDFLTA 1007
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2294-3099 1.04e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 1.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2294 LEESLQQKEVQEERLVEELEDLKVKLHQMQGLTAELDGLRLKHQELSEEhsllLRQKEHLSAGLGEREKALLAETERLTQ 2373
Cdd:pfam15921   94 LNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQED----LRNQLQNTVHELEAAKCLKEDMLEDSN 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2374 DRLDLQRQAEKDHKSLSLRLRALERDLEEKETQDL-ETEQHHKTHNEDLNQRVQALEKQLKHDRQFIEEQAVEREHERDE 2452
Cdd:pfam15921  170 TQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIyEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEA 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2453 FQQEIRS-LEAQLRQ---------------TASVDNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIaanqqaQRDLAECN 2516
Cdd:pfam15921  250 LKSESQNkIELLLQQhqdrieqliseheveITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMY------MRQLSDLE 323

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2517 EEIDKLAGRIRELEQALlndaegKRSISQLEQEL--HRSKLREQELSQDKQALEQQQLSNRLQ--ISALQSKVDETRHCY 2592
Cdd:pfam15921  324 STVSQLRSELREAKRMY------EDKIEELEKQLvlANSELTEARTERDQFSQESGNLDDQLQklLADLHKREKELSLEK 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2593 HDNQREPTQELSDAL--DLAQQSLRSKEQEVEAVVGQLETLQSELGlKEVELKHLALQLEqltNQNADHVNELQEQIDAL 2670
Cdd:pfam15921  398 EQNKRLWDRDTGNSItiDHLRRELDDRNMEVQRLEALLKAMKSECQ-GQMERQMAAIQGK---NESLEKVSSLTAQLEST 473

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2671 KENVSALAILNEEREEQSEAEEPEEENFPSALiEEKNQEIDHLNAEIQRLEQELDNTEDnkaleaELEDLRSQVEHLQse 2750
Cdd:pfam15921  474 KEMLRKVVEELTAKKMTLESSERTVSDLTASL-QEKERAIEATNAEITKLRSRVDLKLQ------ELQHLKNEGDHLR-- 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2751 vmrvrqDTQEEVERLHEVISTLQAELATLGPNLHEVSDsqdgdsinpspapspepdnyTVQEQARRGGANSLKQELSLSY 2830
Cdd:pfam15921  545 ------NVQTECEALKLQMAEKDKVIEILRQQIENMTQ--------------------LVGQHGRTAGAMQVEKAQLEKE 598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2831 SASSHSLRSRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEg 2910
Cdd:pfam15921  599 INDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE- 677

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2911 daeerKLSEEVNDKVQNQEMSTlrdknlhlNSLIAEVQKKEQERVTEMDTLKTKEQE--MEMETEVLRETSLTLER-QVQ 2987
Cdd:pfam15921  678 -----VLKRNFRNKSEEMETTT--------NKLKMQLKSAQSELEQTRNTLKSMEGSdgHAMKVAMGMQKQITAKRgQID 744

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2988 EMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEreasqeeaq 3067
Cdd:pfam15921  745 ALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDK--------- 815

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1838138447 3068 kevlthAEVTLAKADAALRQREAELARLRAEH 3099
Cdd:pfam15921  816 ------ASLQFAECQDIIQRQEQESVRLKLQH 841
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3658-3952 1.11e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3658 RLERLLAEAESRLAEIHSTLAEAHRKVDE---ERERYSRQVDELSRRH---EADATRDRKFISDMRAQLEQERRQGEELA 3731
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEEleeELEQLRKELEELSRQIsalRKDLARLEAEVEQLEERIAQLSKELTELE 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3732 AVMNKLRAELLQSRSKwEEEDRARRAELQREKEAAIQQrvaVETLKEQKQETCCALEMERARSTQQGVELTELKEKLHLI 3811
Cdd:TIGR02168  761 AEIEELEERLEEAEEE-LAEAEAEIEELEAQIEQLKEE---LKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3812 KDKEREREEQweRERRKGRQEQMERERRQERT-----NDKLCELEMLRQQDQQRMQELQHTLVELEREEKEMSAQRLRQH 3886
Cdd:TIGR02168  837 ERRLEDLEEQ--IEELSEDIESLAAEIEELEElieelESELEALLNERASLEEALALLRSELEELSEELRELESKRSELR 914

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3887 NIAASSQHLQSDFQTGSAQHNQQMpssQNLLERMMKENS----ELTECVTSLSQEKATLKHRLTFLEREL 3952
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRI---DNLQERLSEEYSltleEAEALENKIEDDEEEARRRLKRLENKI 981
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2466-2678 1.16e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 1.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2466 QTASVDNKGHRFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALlndAEGKRSISQ 2545
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL---AELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2546 LEQELHRsklREQELSQDKQALEQQQLSNRLQISALQSKVDETrhcyhDNQREPTQELSDALDLAQQSLRSKEQEVEAVV 2625
Cdd:COG4942     95 LRAELEA---QKEELAELLRALYRLGRQPPLALLLSPEDFLDA-----VRRLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1838138447 2626 GQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSALA 2678
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1446-2125 1.62e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 1.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1446 SFKEELQQVQSDItdqyyEELQELKTRHAMELEKLRAKLSdhhvkELTRAHLEAARQVEVeveqrmwcLTEELQSRMTII 1525
Cdd:TIGR02168  236 ELREELEELQEEL-----KEAEEELEELTAELQELEEKLE-----ELRLEVSELEEEIEE--------LQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1526 HTLDSKLAALSKQhDAEVQRNTQKLKQEFAGELVHLEEA------LKQEREDVQEERKRWREELQEKH--QAELSALRSE 1597
Cdd:TIGR02168  298 SRLEQQKQILRER-LANLERQLEELEAQLEELESKLDELaeelaeLEEKLEELKEELESLEAELEELEaeLEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1598 LDREMESERTRLEKELHEEKERLKTLQAALDNDESPQVliVRQRLEAQYDGELQRAKScmaTEVKELTARLQEQGEErLH 1677
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED--RRERLQQEIEELLKKLEE---AELKELQAELEELEEE-LE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1678 QAQERLHGEKAALEQSLAQKYEASLAELKSKHQSELEHERAALLNKERDTLDAKHKAQLDSL-SASHRDQLTATAAELKS 1756
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLkNQSGLSGILGVLSELIS 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1757 KHSAELVALEAALDskrkadiESLEGVLKETNQAQLEASEA------------ELTRKHQEEKDELEMRMLGNMD----- 1819
Cdd:TIGR02168  531 VDEGYEAAIEAALG-------GRLQAVVVENLNAAKKAIAFlkqnelgrvtflPLDSIKGTEIQGNDREILKNIEgflgv 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1820 -----TLESTYLKEVQALRDEIIqLEERHCRGLNLQKSEHRQ---------------VLERHASEQLSIREELRKELAQL 1879
Cdd:TIGR02168  604 akdlvKFDPKLRKALSYLLGGVL-VVDDLDNALELAKKLRPGyrivtldgdlvrpggVITGGSAKTNSSILERRREIEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1880 HiEKFSAMAVELSHVHKtELTAQKEALDTDHcKALETLKKQVLEVEQQHSLALQELSqtctadKEQLLAQQQLQLQDLRG 1959
Cdd:TIGR02168  683 E-EKIEELEEKIAELEK-ALAELRKELEELE-EELEQLRKELEELSRQISALRKDLA------RLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1960 VSARELEACRRELEEESSRQRQHFLE-EVELLKVQSE-ERLQDRINRLKTEFEEqKEARLEDLKRSFTsEQEEKERSYTD 2037
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEaEAEIEELEAQiEQLKEELKALREALDE-LRAELTLLNEEAA-NLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2038 KMSQLTIQLQQLDTVVAQLRAEVGCLQGELEGKRSEMETLDTLLQRRQRETQEGGNLLKMLTDDLQAGKEERRKLNQANE 2117
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911


                   ....*...
gi 1838138447 2118 KLKKVLIE 2125
Cdd:TIGR02168  912 ELRRELEE 919
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2616-3140 1.99e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2616 SKEQEVEAVVGQLETLQSELGLKEVELKhlalQLEQLTNQNADHVNELQEQIDALKENVSALAILNEEREEQSEAEEPEE 2695
Cdd:TIGR04523   30 KQDTEEKQLEKKLKTIKNELKNKEKELK----NLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDL 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2696 ENFPSAlIEEKNQEIDHLNAEIQRLEQELDNTEDNKALEA-ELEDLRSQVEHLQSEVmrvrQDTQEEVERLHEVISTLQA 2774
Cdd:TIGR04523  106 SKINSE-IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLtEIKKKEKELEKLNNKY----NDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2775 ELATLGPNLHEVSDSQDGDSINPSPAPSPEPDNYTVQEQArrggaNSLKQELSLSYSAsshslrsrFKTLQSQLEAAAAE 2854
Cdd:TIGR04523  181 EKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQI-----SELKKQNNQLKDN--------IEKKQQEINEKTTE 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2855 KEGLERLLLT---QEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEGD----------AEERKLSEEV 2921
Cdd:TIGR04523  248 ISNTQTQLNQlkdEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDwnkelkselkNQEKKLEEIQ 327

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2922 NDKVQNQEmsTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEM---ETEVLRETSLTLERQVQEMRAELVDMEE 2998
Cdd:TIGR04523  328 NQISQNNK--IISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKlkkENQSYKQEIKNLESQINDLESKIQNQEK 405

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2999 LVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELtvqlnEREASQEEAQKEVLT----HA 3074
Cdd:TIGR04523  406 LNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNL-----DNTRESLETQLKVLSrsinKI 480

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1838138447 3075 EVTLAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRALLNLETD 3140
Cdd:TIGR04523  481 KQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDE 546
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2400-2635 2.31e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 2.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2400 LEEKET-QDLETEQHHKTHNEDLNQRVQALEKQLKHDRQfIEEQAVEREHERDEfQQEIRSLEAQLRqtasvdnkghrFQ 2478
Cdd:COG4913    218 LEEPDTfEAADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARER-LAELEYLRAALR-----------LW 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2479 DLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALLNDAEgkRSISQLEQELHRSKLREQ 2558
Cdd:COG4913    285 FAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLE--REIERLERELEERERRRA 362

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1838138447 2559 ELSQDKQALEQQQLSNRLQISALQSKVDETRhcyhdnqreptQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSEL 2635
Cdd:COG4913    363 RLEALLAALGLPLPASAEEFAALRAEAAALL-----------EALEEELEALEEALAEAEAALRDLRRELRELEAEI 428
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2516-3145 2.36e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 2.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2516 NEEIDKLAGRIRELEQALL----NDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHC 2591
Cdd:TIGR04523  116 KEQKNKLEVELNKLEKQKKenkkNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNK 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2592 YhdNQREPTQELSDALDLAQQSLRSKEQEVEAVVGQL----ETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQI 2667
Cdd:TIGR04523  196 L--LKLELLLSNLKKKIQKNKSLESQISELKKQNNQLkdniEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ 273

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2668 DALKENvsalailneereeqseaeepeeenfpSALIEEKNQEIDHLNAEIQRLEQELDNtEDNKALEAELEDLRSQVEHL 2747
Cdd:TIGR04523  274 KELEQN--------------------------NKKIKELEKQLNQLKSEISDLNNQKEQ-DWNKELKSELKNQEKKLEEI 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2748 QSEVmrvrQDTQEEVERLHEVISTLQAELATLgpnlhevsdsqdgdsinpspapspEPDNYTVQEQARRgganslKQELS 2827
Cdd:TIGR04523  327 QNQI----SQNNKIISQLNEQISQLKKELTNS------------------------ESENSEKQRELEE------KQNEI 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2828 LSYSASSHSLRSRFKTLQSQleaaaaeKEGLERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQ 2907
Cdd:TIGR04523  373 EKLKKENQSYKQEIKNLESQ-------INDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL 445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2908 KEGDAEERKLSEEVND--KVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQ 2985
Cdd:TIGR04523  446 TNQDSVKELIIKNLDNtrESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEK 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2986 VQEMRAELVDMEELVDEERIKIKTLKTVKgelsaERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEE 3065
Cdd:TIGR04523  526 IEKLESEKKEKESKISDLEDELNKDDFEL-----KKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKD 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3066 AQKEvlthaevtLAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRALLNLETDNQRLK 3145
Cdd:TIGR04523  601 LIKE--------IEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESK 672
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2985-3167 2.40e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 2.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2985 QVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQE 3064
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3065 EAQKE------------------VLTHAE--VTLAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLH 3124
Cdd:COG4942    101 AQKEElaellralyrlgrqpplaLLLSPEdfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1838138447 3125 EEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEELAYQQR 3167
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
PTZ00121 PTZ00121
MAEBL; Provisional
 2811-3162 2.67e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 2.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2811 QEQARRGGANSLKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGhgeEFGKRLTAEREKADKL 2890
Cdd:PTZ00121  1373 KEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA---DEAKKKAEEAKKADEA 1449

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2891 QsvltlKEAELDEVKAQKEGDAEERKLSEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEM 2970
Cdd:PTZ00121  1450 K-----KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA 1524

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2971 ETEVLRETSLTLE--RQVQEMRA--ELVDMEELVDEERIK----IKTLKTVKGELSAERETLRRREGKLQEEIENLRQEA 3042
Cdd:PTZ00121  1525 DEAKKAEEAKKADeaKKAEEKKKadELKKAEELKKAEEKKkaeeAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEE 1604

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3043 TSMRAciqELTVQLNEREASQEEAQKEVLTHAEVTLAKADAALRQREAELARLRAEHQALKAEltEVKQGLSTSTERAEK 3122
Cdd:PTZ00121  1605 KKMKA---EEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA--EEAKKAEEDKKKAEE 1679

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1838138447 3123 LH--EEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEEL 3162
Cdd:PTZ00121  1680 AKkaEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEEL 1721
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2611-2779 3.14e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 3.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2611 QQSLRSKEQEVEAVV----GQLETLQSELGLKEVEL-----KHLALQLEQLTNQNADHVNELQEQIDALKENVSAL-AIL 2680
Cdd:COG3206    163 EQNLELRREEARKALefleEQLPELRKELEEAEAALeefrqKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAeARL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2681 NEEREEQSEAEEPEEENFPSALIEEKNQEIDHLNAEIQRLEQEL-DNTEDNKALEAELEDLRSQvehLQSEVMRVRQDTQ 2759
Cdd:COG3206    243 AALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYtPNHPDVIALRAQIAALRAQ---LQQEAQRILASLE 319

                          170       180
                   ....*....|....*....|
gi 1838138447 2760 EEVERLHEVISTLQAELATL 2779
Cdd:COG3206    320 AELEALQAREASLQAQLAQL 339
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3506-3885 3.39e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 3.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3506 QVESQLRAELEESQKQLKCAHDTQQEhknkmQSVRVAVAEGEEALRREQVRVQELQQQLEQERALSQRKDREKEERREAL 3585
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEEL-----EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3586 HVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKELKLQDKTRLERLLAE 3665
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3666 AESRLAEIHSTLAEAHRKVDEE-----------RERYSR----QVDELSRRHEADATRDRKFISDMRAQLEQERRQGEEL 3730
Cdd:COG1196    535 AYEAALEAALAAALQNIVVEDDevaaaaieylkAAKAGRatflPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR 614

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3731 AA------VMNKLRAELLQSRSKWEEEDRARRAELQREKEAAIQQRVAVETLKEQKQETCCALEMERARSTQQGVELtEL 3804
Cdd:COG1196    615 YYvlgdtlLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE-EL 693

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3805 KEKLHLIKDKEREREEQWERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQHTLVELEREEKEMSAQRLR 3884
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773


                   .
gi 1838138447 3885 Q 3885
Cdd:COG1196    774 R 774
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1534-1801 3.48e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 50.22  E-value: 3.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1534 ALSKQHDAEVQRntQKLKQEFAGELVHLEEALKQ---------------EREDVQEERKRWREELQEKHQAeLSALRSEL 1598
Cdd:NF012221  1560 ALADKERAEADR--QRLEQEKQQQLAAISGSQSQlestdqnaletngqaQRDAILEESRAVTKELTTLAQG-LDALDSQA 1636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1599 DREMES-ERTRLEKELHEekerLKTLQAALDNDESpqvlIVRQRLEA---QYDGELQRAKSCMAtevKELTArlQEQGEE 1674
Cdd:NF012221  1637 TYAGESgDQWRNPFAGGL----LDRVQEQLDDAKK----ISGKQLADakqRHVDNQQKVKDAVA---KSEAG--VAQGEQ 1703

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1675 RLHQAQERLHGEKAALEQ----SLAQKYEASLAELK-----SKHQSELEHERAALLNKerdTLDAKHKAQLDSLSASHR- 1744
Cdd:NF012221  1704 NQANAEQDIDDAKADAEKrkddALAKQNEAQQAESDanaaaNDAQSRGEQDASAAENK---ANQAQADAKGAKQDESDKp 1780

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1838138447 1745 DQLTATAAELKSK-HSAELVALEAA---LDSKRKADIESLEGvLKETNQAQLEASEAELTR 1801
Cdd:NF012221  1781 NRQGAAGSGLSGKaYSVEGVAEPGShinPDSPAAADGRFSEG-LTEQEQEALEGATNAVNR 1840
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2504-3125 3.65e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.22  E-value: 3.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2504 ANQQAQRDLAECNEEIDKLAGRIRELEQALLNDAEGKRSI--------SQLEQELHRSKLREQELSQDKQALEQQQLSNR 2575
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYksdetliaSRQEERQETSAELNQLLRTLDDQWKEKRDELN 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2576 LQISALQSKVDETRH---CYHDNQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQl 2652
Cdd:pfam12128  308 GELSAADAAVAKDRSeleALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKE- 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2653 tnQNADHVNELQEQIDALKENVSAL------------AILNEEREEQSEAEEPEEENFPSALIEEKNQeIDHLNAEIQRL 2720
Cdd:pfam12128  387 --QNNRDIAGIKDKLAKIREARDRQlavaeddlqaleSELREQLEAGKLEFNEEEYRLKSRLGELKLR-LNQATATPELL 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2721 EQELDNTEDNKALEAELEDLRSQVEHLQSEVMRVRQDTQEEVERLHEVISTLQaELATLGPNLHEVSDSQDGDSI----N 2796
Cdd:pfam12128  464 LQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLE-ERQSALDELELQLFPQAGTLLhflrK 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2797 PSPAPSPEPDNYTVQEQARRGGANSLKQELSLSYSASSHSLRSRFKTLQSQLEAAAaekeglerllltqEEEYRGHGEEF 2876
Cdd:pfam12128  543 EAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAAS-------------EEELRERLDKA 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2877 GKRLTAEREKADKLQSVLTLKEAELDEVKAqKEGDAEERKLSEEVNDKVQNQEMSTLRDKnlhLNSLIAEVQKKEQERVT 2956
Cdd:pfam12128  610 EEALQSAREKQAAAEEQLVQANGELEKASR-EETFARTALKNARLDLRRLFDEKQSEKDK---KNKALAERKDSANERLN 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2957 EMDT-LKTKEQEMEMETEVLRETSLTLERQVQEMRAELV----DMEELVDEERIK--------IKTLKT----------- 3012
Cdd:pfam12128  686 SLEAqLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEgaldAQLALLKAAIAArrsgakaeLKALETwykrdlaslgv 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3013 ---VKGELSAERETLRRRegklQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEVLTHAEVTLAKADAALRQRE 3089
Cdd:pfam12128  766 dpdVIAKLKREIRTLERK----IERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRR 841

                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 1838138447 3090 AELARLRAEHQALKAELTEVKQGLSTSTERAEKLHE 3125
Cdd:pfam12128  842 AKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKE 877
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 534-1404 3.95e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.97  E-value: 3.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  534 SEQQFEQTDLEKELLNQQCGELRDELLLKDRDLNVLREEVINTAEELEEAR----------SRWGQVTEELRQALWELEE 603
Cdd:pfam02463  175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYllyldylklnEERIDLLQELLRDEQEEIE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  604 EKEKKRLAEEEMNLKAHEQDNLKSKLSALMEEREKEKAVLLTGKEAAETSLLVPAITPSEEEDELvgELKKKKQQDLLLS 683
Cdd:pfam02463  255 SSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKES--EKEKKKAEKELKK 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  684 QQEIkqpaISAEQILELRDDKPLQTLQVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNDLQEQIDALKAQ 763
Cdd:pfam02463  333 EKEE----IEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  764 CEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDRLQGELEKSLDSLDTAEQVKSELESQIFC 843
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  844 LKQNLAKLEEAQAQTEQEREERRRKEEEMD---DQIKKMEQVLEEELEQFESLLKAKDVELSEAKEKWEEESQEKETELL 920
Cdd:pfam02463  489 LLSRQKLEERSQKESKARSGLKVLLALIKDgvgGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVR 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  921 GVRHHLEEQRREREEEVKALLEKQVLAVEEETERLKTShqQEIKDLMERHRQEISELNTHLESEQLKQQVNMEEEQKRQI 1000
Cdd:pfam02463  569 ALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLA--QLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1001 SFIKQVTEREHERMLSELSAKHNEELTQLRTEVSLELRESMEAAHQAELLQHQVQKRSELEAMRLSLTNAHVSQLEQESA 1080
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1081 LTEAQGSPRDTFAQEIALLKAQHQAELDHIRQQEKLRELQQQPMNDLQQQWETLVAQERAAMEEEQAKDIQALRSQWDKN 1160
Cdd:pfam02463  727 VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1161 AESRESNLQMFLSEmQNSLTATQTDLTQTLKALSQTQAELQRSGAKLQELQTSSKDMNQELEAELEQACADRDAAARSLE 1240
Cdd:pfam02463  807 EEELKEEAELLEEE-QLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLK 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1241 ELMSSHKAVLQEREQQALHLEEKEEQLKQEVLRLQEERSSLKKNSEQEVGQLWTQLESMRTSRQELGELKEQLLARSARV 1320
Cdd:pfam02463  886 DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRL 965

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1321 DDIERLKTEFNEQKREIKEQNEAELESLRRYfEQRLRATEEGHREEIALLQLRLVERALEESVIRTADDSFSSISQ---G 1397
Cdd:pfam02463  966 LLAKEELGKVNLMAIEEFEEKEERYNKDELE-KERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLelgG 1044


                   ....*..
gi 1838138447 1398 QAEEEKD 1404
Cdd:pfam02463 1045 SAELRLE 1051
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2965-3163 4.19e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.63  E-value: 4.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2965 EQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLktvkgELSAERETLRRREGKLQEEIENLRQEATS 3044
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLV-----DLSEEAKLLLQQLSELESQLAEARAELAE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3045 MRACIQELTVQLnereASQEEAQKEVLTHAEVTLAKAD-AALRQREAEL-ARLRAEH---QALKAELTEVKQGLStster 3119
Cdd:COG3206    238 AEARLAALRAQL----GSGPDALPELLQSPVIQQLRAQlAELEAELAELsARYTPNHpdvIALRAQIAALRAQLQ----- 308

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1838138447 3120 aeklheegQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEELA 3163
Cdd:COG3206    309 --------QEAQRILASLEAELEALQAREASLQAQLAQLEARLA 344
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3616-3969 4.71e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.67  E-value: 4.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3616 ELQIEQSRSELleKRLDDTQKELgdERQLsanqKELKLQDKTRLERLLAEAESRLAEIHSTLAEAHRKvDEERERYSRQV 3695
Cdd:TIGR02168  178 ERKLERTRENL--DRLEDILNEL--ERQL----KSLERQAEKAERYKELKAELRELELALLVLRLEEL-REELEELQEEL 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3696 DELSRRHEADATRdrkfISDMRAQLEQERRQGEELAAVMNKLRAELLQSRSKWEEEDRaRRAELQREKEAAIQQRVAVET 3775
Cdd:TIGR02168  249 KEAEEELEELTAE----LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ-QKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3776 LKEQKQETccaLEMERARSTQQGVELTELKEKLHLIKDKEREREEQWERERRKGRQEQMERERRQERTNDKLCELEMLRQ 3855
Cdd:TIGR02168  324 QLEELESK---LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3856 QDQQRMQELQHTLVELEREEKEMSAQRLRQHNIAASSQHLQ-SDFQTGSAQHNQQMPSSQNLLERMMKENSELTECVTSL 3934
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 1838138447 3935 SQEKATLKHRLTFLERELRLTENELAKVTTETENR 3969
Cdd:TIGR02168  481 ERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515
PTZ00121 PTZ00121
MAEBL; Provisional
 3449-4017 5.59e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 5.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3449 DRRDNPSSIPPMGWQQEKRALQETVVALRELLCRMAQRPTQtdhRVEGDWHGDRVDGQVESQLRAELEESQKQLKCAHDT 3528
Cdd:PTZ00121  1069 DEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETG---KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA 1145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3529 QQEHKNKMQSVRVAVAEG---EEALRREQVR-VQELQQQLEQERALSQRKDREKEERREALHVSSEQQRSEVMALKGLVE 3604
Cdd:PTZ00121  1146 RKAEDAKRVEIARKAEDArkaEEARKAEDAKkAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKK 1225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3605 QERVACSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKELKLQDKTRLERLLAEAESRLAEiHSTLAEAHRKV 3684
Cdd:PTZ00121  1226 AEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKA 1304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3685 DEERERY--SRQVDELSRRHE-----ADATRDR---KFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRSKWEEEDRA 3754
Cdd:PTZ00121  1305 DEAKKKAeeAKKADEAKKKAEeakkkADAAKKKaeeAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAK 1384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3755 RRAELQRE----KEAAIQQRVAVETLKEQKQETCCALEM----ERARSTQQGVELTELKEKLHLIKDKEREREEQWERER 3826
Cdd:PTZ00121  1385 KKAEEKKKadeaKKKAEEDKKKADELKKAAAAKKKADEAkkkaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3827 RKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQhtlvelEREEKEMSAQRLRQHNIAASSQHLQSDFQTGSAQH 3906
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAK------KAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE 1538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3907 NQQMPSSQNLLERMMKENSELTECVTSLSQEKATLKHRLTFLERELRLTENELAKVTTETENRPTKDVISNTKVQRLYER 3986
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1838138447 3987 YLRAESFRKALVYQKRYLVLLLGGFQECEQA 4017
Cdd:PTZ00121  1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKA 1649
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 3502-3775 5.90e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 5.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3502 RVDGQVESqLRAELEESQKQLKcahDTQQEHKNKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERALSQRKDREKEER 3581
Cdd:TIGR02169  241 AIERQLAS-LEEELEKLTEEIS---ELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3582 REALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKELKLQDKTRLER 3661
Cdd:TIGR02169  317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3662 LLAEAESRLAEIhSTLAEAHRKVDEERERYSRQVDELSRRHEADATRdrkfISDMRAQLEQERRQGEELAAVMNKLRAEL 3741
Cdd:TIGR02169  397 LKREINELKREL-DRLQEELQRLSEELADLNAAIAGIEAKINELEEE----KEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1838138447 3742 LQSRSKWEEEDRaRRAELQREKEAAIQQRVAVET 3775
Cdd:TIGR02169  472 YDLKEEYDRVEK-ELSKLQRELAEAEAQARASEE 504
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2847-3206 7.18e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 7.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2847 QLEAAAAEKEGLERLLLTQEEEYRGHgEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERKLSEEVNDKVQ 2926
Cdd:PRK03918   232 ELEELKEEIEELEKELESLEGSKRKL-EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELR 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2927 N--QEMSTLRDKNLHLNSLIAEVQKKEQErvteMDTLKTKEQEMEMETEVLRETSLTLErqvqEMRAELVDMEELvdEER 3004
Cdd:PRK03918   311 EieKRLSRLEEEINGIEERIKELEEKEER----LEELKKKLKELEKRLEELEERHELYE----EAKAKKEELERL--KKR 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3005 IKIKTLKTVKGELsaerETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQ-----------EEAQKEVLTH 3073
Cdd:PRK03918   381 LTGLTPEKLEKEL----EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgreltEEHRKELLEE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3074 AEVTLAKADAALRQREAELARLRAEHQALKAELTEVKQgLSTSTERAEKLHE-EGQTKDRALLNLETDN---QRLKAQLR 3149
Cdd:PRK03918   457 YTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE-LIKLKELAEQLKElEEKLKKYNLEELEKKAeeyEKLKEKLI 535

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1838138447 3150 ALQEDLAVQEEELAYQQRELQQLRQHCDQQDTLPHQRGHTQKDISHRAFEDLVSVSR 3206
Cdd:PRK03918   536 KLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2982-3123 7.22e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 7.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2982 LERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAER--------ETLRRREGKLQEEIENLRQEATSMRACIQELT 3053
Cdd:COG4913    293 LEAELEELRAELARLEAELERLEARLDALREELDELEAQIrgnggdrlEQLEREIERLERELEERERRRARLEALLAALG 372

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1838138447 3054 VQLNEREASQEEAQKEVLTHAEVT---LAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKL 3123
Cdd:COG4913    373 LPLPASAEEFAALRAEAAALLEALeeeLEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL 445
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2392-2674 7.40e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 7.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2392 RLRALERDLEE--KETQDLETEQhhkthnEDLNQRVQALEKQLKHDRQFIEEQAVEREheRDEFQQEIRSLEAqlrqtAS 2469
Cdd:COG4913    618 ELAELEEELAEaeERLEALEAEL------DALQERREALQRLAEYSWDEIDVASAERE--IAELEAELERLDA-----SS 684

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2470 VDnkghrFQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRIRELEqallnDAEGKRSISQLEQE 2549
Cdd:COG4913    685 DD-----LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAE-----DLARLELRALLEER 754

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2550 LHRSKLREQElSQDKQALEQQQLSNRLQISALQSKVDETRHCYHDNQREPTQELSDALDlaqqslrskeqEVEAVVGQLE 2629
Cdd:COG4913    755 FAAALGDAVE-RELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLE-----------SLPEYLALLD 822

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1838138447 2630 TLQSElGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKENV 2674
Cdd:COG4913    823 RLEED-GLPEYEERFKELLNENSIEFVADLLSKLRRAIREIKERI 866
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1125-1696 7.53e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 7.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1125 NDLQQQWETLV-AQERAAMEEEQAKDIQALRSQWDKNAESRES-NLQMFLSEMQNSLTAtQTDLTQTLKALSQTQAELQR 1202
Cdd:COG4913    228 DALVEHFDDLErAHEALEDAREQIELLEPIRELAERYAAARERlAELEYLRAALRLWFA-QRRLELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1203 SGAKLQELQTSSKDMNQELEAELEQACADRDAAARSLEELMSSHKAVLQEREQQALhleekeeqlkqevlRLQEERSSLK 1282
Cdd:COG4913    307 LEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRA--------------RLEALLAALG 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1283 KNSEQEVGQLWTQLESMRTSRQELGELKEQL-LARSARVDDIERLKTEFNEQKREIK--EQN----EAELESLRRYFEQR 1355
Cdd:COG4913    373 LPLPASAEEFAALRAEAAALLEALEEELEALeEALAEAEAALRDLRRELRELEAEIAslERRksniPARLLALRDALAEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1356 LRATE-------------EGHRE-----EIALLQLR---LVERALEESVIRTADD-------SFSSISQGQAEEEKDHLF 1407
Cdd:COG4913    453 LGLDEaelpfvgelievrPEEERwrgaiERVLGGFAltlLVPPEHYAAALRWVNRlhlrgrlVYERVRTGLPDPERPRLD 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1408 SDAVfklekhkealdnvSLQLEEKHSMDLSYLQSSMSLSFkeELQQVQSDitdqyyEELQelKTRHAMELEKLRAKLSDH 1487
Cdd:COG4913    533 PDSL-------------AGKLDFKPHPFRAWLEAELGRRF--DYVCVDSP------EELR--RHPRAITRAGQVKGNGTR 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1488 HVKELTRAHLE-------AARQVEVEVEQRmwcltEELQSRmtiIHTLDSKLAALSKQHDAEVQRNT--QKLKQEFAGEL 1558
Cdd:COG4913    590 HEKDDRRRIRSryvlgfdNRAKLAALEAEL-----AELEEE---LAEAEERLEALEAELDALQERREalQRLAEYSWDEI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1559 VHleEALKQEREDVQEERKRWR---------EELQEKHQAELSALRSELDrEMESERTRLEKELHEEKERLKTLQAALDN 1629
Cdd:COG4913    662 DV--ASAEREIAELEAELERLDassddlaalEEQLEELEAELEELEEELD-ELKGEIGRLEKELEQAEEELDELQDRLEA 738

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1838138447 1630 DESPQVLIVRQRLEAQYDGELQRakscmatevkELTARLQEQGEERLHQAQERLHGEKAALEQSLAQ 1696
Cdd:COG4913    739 AEDLARLELRALLEERFAAALGD----------AVERELRENLEERIDALRARLNRAEEELERAMRA 795
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3713-4000 8.87e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 8.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3713 ISDMRAQLEQERRQGE------ELAAVMNKLRAELLQSRskweeeDRARRAELQREKEAAIQQRVAVETLKEQKQETCCA 3786
Cdd:COG1196    195 LGELERQLEPLERQAEkaeryrELKEELKELEAELLLLK------LRELEAELEELEAELEELEAELEELEAELAELEAE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3787 LEMERARSTQQGVELTELKEKLHLIKDKEREREEQWERERRKGRQEQMERERRQErtndklcELEMLRQQDQQRMQELQH 3866
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE-------ELAELEEELEELEEELEE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3867 TLVELEREEKEMSAQRLRQHNIAASSQHLQSDFQTGSAQHNQQmpssQNLLERMMKENSELTECVTSLSQEKATLKHRLT 3946
Cdd:COG1196    342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL----AEELLEALRAAAELAAQLEELEEAEEALLERLE 417

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1838138447 3947 FLERELRLTENELAKVTTETENRPTKDVISNTKVQRLYERYLRAESFRKALVYQ 4000
Cdd:COG1196    418 RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3657-3997 1.31e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.39  E-value: 1.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3657 TRLERLLAEAESRLAEIH--STLAEAHRKVDEERERysrqvdelsRRHEADATRDRKFisdmRAQLEQERRQGEELAAVM 3734
Cdd:COG1196    189 ERLEDILGELERQLEPLErqAEKAERYRELKEELKE---------LEAELLLLKLREL----EAELEELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3735 NKLRAELLQSRSKWEEEdRARRAELQREKEAAIQQRVAVETLKEQKQEtccALEMERARSTQQGVELTELkeklhlikdk 3814
Cdd:COG1196    256 EELEAELAELEAELEEL-RLELEELELELEEAQAEEYELLAELARLEQ---DIARLEERRRELEERLEEL---------- 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3815 erereeqwERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQHTLVELEREEKEMSAQRLRQHNIAASSQH 3894
Cdd:COG1196    322 --------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3895 LQSDFQTGSAQHNQQMPSSQNLLERMMKENSELTECVTSLSQEKATLKHRLTFLERELRLTENELAKVTTETENRPTKDV 3974
Cdd:COG1196    394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                          330       340
                   ....*....|....*....|...
gi 1838138447 3975 ISNTKVQRLYERYLRAESFRKAL 3997
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLL 496
AcrA COG0845
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ...
 3074-3164 1.43e-04

Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];


Pssm-ID: 440606 [Multi-domain]  Cd Length: 324  Bit Score: 47.25  E-value: 1.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3074 AEVTLAKADAALRQREAELARLRAEHQALKAELtevkqglststERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQE 3153
Cdd:COG0845     52 ARLDPPDLQAALAQAQAQLAAAQAQLELAKAEL-----------ERYKALLKKGAVSQQELDQAKAALDQAQAALAAAQA 120

                           90
                   ....*....|.
gi 1838138447 3154 DLAVQEEELAY 3164
Cdd:COG0845    121 ALEQARANLAY 131
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 3613-3971 1.44e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 1.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3613 LRRELQIEQSRSELLEKRLDDTQKELGDERQlsANQKELKLQDKTRLERLLAEAESRLAEI--HSTLAEAHRKVDEERER 3690
Cdd:pfam17380  271 LNQLLHIVQHQKAVSERQQQEKFEKMEQERL--RQEKEEKAREVERRRKLEEAEKARQAEMdrQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3691 YSRQVDELSRRHEADATRDRKFISDMRAQLEQERRQGEELAAvMNKLRAELLQSRS-KWEEEDRARRAELQREKEAAIQQ 3769
Cdd:pfam17380  349 ELERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQK-NERVRQELEAARKvKILEEERQRKIQQQKVEMEQIRA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3770 RvavetLKEQKQETCCALEMERARSTQQgVELTELKeklhlikdkerereeqwererrkgRQEQMERERRQERTNDKLCE 3849
Cdd:pfam17380  428 E-----QEEARQREVRRLEEERAREMER-VRLEEQE------------------------RQQQVERLRQQEEERKRKKL 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3850 LEMLRQQDQQRMQELQHTLVELEREEKEMSAqrLRQHNIAASSQHLQSDFQTGSAQHNQ-QMPSSQNLLERMMKENSELT 3928
Cdd:pfam17380  478 ELEKEKRDRKRAEEQRRKILEKELEERKQAM--IEEERKRKLLEKEMEERQKAIYEEERrREAEEERRKQQEMEERRRIQ 555

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1838138447 3929 ECVTSLSQEKATLKHRLTFLERELRLTENELAKVTTETENRPT 3971
Cdd:pfam17380  556 EQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEATTPIT 598
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2483-2677 1.45e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2483 QVESLQAIIKDKTEDHDSLIAANQQAQ--RDLAECNEEIDKLAGRIRELEQ--ALLNDAEGKRSISQLEQELhrsklreQ 2558
Cdd:COG4913    226 AADALVEHFDDLERAHEALEDAREQIEllEPIRELAERYAAARERLAELEYlrAALRLWFAQRRLELLEAEL-------E 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2559 ELSQDKQALEQQQLSNRLQISALQSKVDETRHCYHDNQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLK 2638
Cdd:COG4913    299 ELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPAS 378

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1838138447 2639 EVELKHLALQLEQLTNQNADHVNELQEQIDALKENVSAL 2677
Cdd:COG4913    379 AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2266-2723 1.48e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 1.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2266 EAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERLVEELEDLKVKLHQMQGLTAELDGLRLKHQELSEEHSL 2345
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2346 L-----LRQKEHLSAGLGEREKALLAETERLTQDRLDLqRQAEKDHKSLSLRLRALERDLEEKETQDLETeqhHKTHNED 2420
Cdd:COG4717    128 LplyqeLEALEAELAELPERLEELEERLEELRELEEEL-EELEAELAELQEELEELLEQLSLATEEELQD---LAEELEE 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2421 LNQRVQALEKQLKHDRQFIEE-----QAVEREHERDEFQQEIRSLEAQLRQTASVDNKGHRFQDLVLQVESLQAIIKDKT 2495
Cdd:COG4717    204 LQQRLAELEEELEEAQEELEEleeelEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVL 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2496 EDHDSLIAANQQAQRDLAECNEEIDKLAgRIRELEQALLNDAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNR 2575
Cdd:COG4717    284 GLLALLFLLLAREKASLGKEAEELQALP-ALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2576 LQISALQSKVDETRHCYHDNQREptqELSDALDLAQQsLRSKEQEVEAVVGQLETLQSEL-----GLKEVELKHLALQLE 2650
Cdd:COG4717    363 LQLEELEQEIAALLAEAGVEDEE---ELRAALEQAEE-YQELKEELEELEEQLEELLGELeelleALDEEELEEELEELE 438

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1838138447 2651 QLTNQNADHVNELQEQIDALKENVSALAilneereeqseaeepeeenfPSALIEEKNQEIDHLNAEIQRLEQE 2723
Cdd:COG4717    439 EELEELEEELEELREELAELEAELEQLE--------------------EDGELAELLQELEELKAELRELAEE 491
PRK11281 PRK11281
mechanosensitive channel MscK;
2375-2671 1.62e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.98  E-value: 1.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2375 RLDLQRQAE--KDHKSLSLRLRALERDLEEkeTQD-LETEQHHKTHNEDLNQRVQALEKQLKHDRQFIE---EQAVEREH 2448
Cdd:PRK11281    38 EADVQAQLDalNKQKLLEAEDKLVQQDLEQ--TLAlLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEalkDDNDEETR 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2449 ERDEfQQEIRSLEAQLRQTasvdnkghrfqdlvlqVESLQAIIKDKTEDHDSLIAANQQAQRDLAecneEIDKLAGRIRE 2528
Cdd:PRK11281   116 ETLS-TLSLRQLESRLAQT----------------LDQLQNAQNDLAEYNSQLVSLQTQPERAQA----ALYANSQRLQQ 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2529 LEQALLNDAEGKRSIS-----QLEQELH----RSKLREQELSQDK--QALEQQQL------SNRLQ--ISALQSKVDETR 2589
Cdd:PRK11281   175 IRNLLKGGKVGGKALRpsqrvLLQAEQAllnaQNDLQRKSLEGNTqlQDLLQKQRdyltarIQRLEhqLQLLQEAINSKR 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2590 HCYHDNQREPTQELSDALDLAQQSLRSKEQEVEAVVGQ--LETLQS--ELGLKEVELKHlalQLEQL--TNQNadhvneL 2663
Cdd:PRK11281   255 LTLSEKTVQEAQSQDEAARIQANPLVAQELEINLQLSQrlLKATEKlnTLTQQNLRVKN---WLDRLtqSERN------I 325


                   ....*...
gi 1838138447 2664 QEQIDALK 2671
Cdd:PRK11281   326 KEQISVLK 333
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
3025-3163 1.89e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 1.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3025 RRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQK-EVLTHAEVTLAKADAALRQREAELARLRA---EHQ 3100
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlAEYSWDEIDVASAEREIAELEAELERLDAssdDLA 688

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1838138447 3101 ALKAELTEVKQGLSTSTERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDLAVQEEELA 3163
Cdd:COG4913    689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 3611-3839 2.10e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3611 SNLRRELQIEQSRSELLEKRLDDTQKELGD-ERQLSANQKELKlqdktRLERLLAEAESRLAEIHSTLAEAHRKVDEERE 3689
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAAlERRIAALARRIR-----ALEQELAALEAELAELEKEIAELRAELEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3690 RYSRQVDELSRRHEADATrdrKFISDMRAQLEQERRQgeelaavmnKLRAELLQSRSKWEEEDRARRAELQREKEAAIQQ 3769
Cdd:COG4942    105 ELAELLRALYRLGRQPPL---ALLLSPEDFLDAVRRL---------QYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3770 RVAVETLKEQKQETCCALEMERARSTQQGVELTELKEKLHLIKDKEREREEQWERERRKGRQEQMERERR 3839
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
3049-3163 2.14e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.55  E-value: 2.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3049 IQELTVQLNEREasqEEAQKEVLTHAEVTLAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQ 3128
Cdd:COG2433    382 LEELIEKELPEE---EPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEER 458

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1838138447 3129 T---KDRALLNLETDNQRLKAQLRALQEDLAVQEEELA 3163
Cdd:COG2433    459 ReirKDREISRLDREIERLERELEEERERIEELKRKLE 496
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2201-2652 2.21e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.37  E-value: 2.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2201 EAALNACSRLRHTVDTLLDLLNHANKQLEQTHGFHHSLEEKFSQGREDSAQLLVQHKILLEQLDQEAKLKsELQLEYHKT 2280
Cdd:PRK03918   220 REELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELK-EKAEEYIKL 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2281 EGLLEGYVAEKALLEESLQQKEVQEERLVEELEDLKVKLHQMQGLTAELDGLRLKHQELSEEHSLLlrqkehlsaglgER 2360
Cdd:PRK03918   299 SEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY------------EE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2361 EKALLAETERLTQDRLDLQ-RQAEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLNQRVQALEKQLKHDRQFI 2439
Cdd:PRK03918   367 AKAKKEELERLKKRLTGLTpEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELT 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2440 EEQAVER-----------EHERDEFQQEIRSLEAQLRQTASVDNKGHRFQDLVLQVESLQAiIKDKTEDHDslIAANQQA 2508
Cdd:PRK03918   447 EEHRKELleeytaelkriEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE-LEEKLKKYN--LEELEKK 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2509 QRDLAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSklrEQELSQDKQALEQQQLSNrlqISALQSKVDET 2588
Cdd:PRK03918   524 AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDEL---EEELAELLKELEELGFES---VEELEERLKEL 597

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1838138447 2589 RHCYhdnqrEPTQELSDaldlAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQL 2652
Cdd:PRK03918   598 EPFY-----NEYLELKD----AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEL 652
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 123-760 3.06e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 3.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  123 QLKQLQEAVEKRNEIIARLSSNLQEALASRDQVQLEAQSLAGQIQGLQRQLQQTSVEFLRIKSQSgAEVLNTRQPHGRCS 202
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL-ARLEQDIARLEERR 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  203 QDADLNHKEApsgsaapeTISCVEGFSTDTALEKLRVELEEERKNSQRIYAELALEMEKHQHVLSLLEKEKNSREEEQKE 282
Cdd:COG1196    312 RELEERLEEL--------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  283 KEEQLQDLQMQFSLVQTQCLEMQQYKEEKEKLNREVLELRKRLQEEADAERRLGEEVASSALRLQRQEEEMLRLKEEHRE 362
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  363 EVEGVRQLLEEREKELKFREEEVLGLKASKNRQNKAKAGFSFDEKVNLdEAELETGPVENSMNVSVDILMERYMSSHRPA 442
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK-AALLLAGLRGLAGAVAVLIGVEAAYEAALEA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  443 HSQSSVASDSLERCGQLDISADYSFELNSEVLGDEPLLSISNRFLEEDDNRHNTStpqcspgiplpdnsnpqspsQWLYD 522
Cdd:COG1196    543 ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI--------------------GAAVD 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  523 STPDELETSKLSEQQFEQTDLEKELLNqqcgELRDELLLKDRDLNVLREEVINTAEELEEARSRWGQVTEELRQALWELE 602
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVA----ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  603 EEKEKKRLAEEEMNLKAHEQDNLKSKLSALMEEREKEKavlltgkeaaetsllvpaitpsEEEDELVGELKKKKQQDLLL 682
Cdd:COG1196    679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEER----------------------LEEELEEEALEEQLEAEREE 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  683 SQQEIKQPAISAEQILELRDDKPLQTLQVEAMVGQLETLQSELG----LKEVELKHLALQLEQLTNQNAdhvnDLQEQID 758
Cdd:COG1196    737 LLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGpvnlLAIEEYEELEERYDFLSEQRE----DLEEARE 812


                   ..
gi 1838138447  759 AL 760
Cdd:COG1196    813 TL 814
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2255-2773 3.09e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.94  E-value: 3.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2255 QHKILLEQLDQEAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERLVEELEDLKVKLHQMQGLTAELDGLRL 2334
Cdd:TIGR04523  139 NIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLES 218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2335 KHQELSEEHSLLLRQKEHLSAGLGEREKALLAETERLTQdrldLQRQAEKDHKSLSLRLRALERDleEKETQDLETE-QH 2413
Cdd:TIGR04523  219 QISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQ----LKDEQNKIKKQLSEKQKELEQN--NKKIKELEKQlNQ 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2414 HKTHNEDLN-QRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQTASvdnkghRFQDLVLQVESLQAIIK 2492
Cdd:TIGR04523  293 LKSEISDLNnQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK------ELTNSESENSEKQRELE 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2493 DKTEDHDSLIAANQQAqrdlaecNEEIDKLAGRIRELEQALLNDaegKRSISQLEQELHRSKLREQELSQDKQALEQQQL 2572
Cdd:TIGR04523  367 EKQNEIEKLKKENQSY-------KQEIKNLESQINDLESKIQNQ---EKLNQQKDEQIKKLQQEKELLEKEIERLKETII 436

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2573 SNRLQISALQSKVDETRHCYH------DNQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETL--------------- 2631
Cdd:TIGR04523  437 KNNSEIKDLTNQDSVKELIIKnldntrESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLneekkeleekvkdlt 516

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2632 --QSELGLKEVELKHLALQLEQLTNQNADHVN----------------ELQEQIDALKENVSALAILNEEREEQSEAEEP 2693
Cdd:TIGR04523  517 kkISSLKEKIEKLESEKKEKESKISDLEDELNkddfelkkenlekeidEKNKEIEELKQTQKSLKKKQEEKQELIDQKEK 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2694 EEENFPS------ALIEEKNQEIDHLNAEIQRLEQELDNtednkaLEAELEDLRSQVEHLQSEVMRVRQDTQEEVERLHE 2767
Cdd:TIGR04523  597 EKKDLIKeieekeKKISSLEKELEKAKKENEKLSSIIKN------IKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKE 670


                   ....*.
gi 1838138447 2768 VISTLQ 2773
Cdd:TIGR04523  671 SKTKID 676
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2561-2779 3.48e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2561 SQDKQALEQQQLSNRLQISALQSKVDETRhcyhdnqreptqelsDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEV 2640
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALK---------------KEEKALLKQLAALERRIAALARRIRALEQELAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2641 ELKHLALQLEQLTNQNADHVNELQEQIDAL--KENVSALAIL----NEEREEQSEAEEPEEENFPSALIEEKNQEIDHLN 2714
Cdd:COG4942     84 ELAELEKEIAELRAELEAQKEELAELLRALyrLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1838138447 2715 AEIQRLEQELDNTE----DNKALEAELEDLRSQVEHLQSEVMRVRQDTQEEVERLHEVISTLQAELATL 2779
Cdd:COG4942    164 ALRAELEAERAELEallaELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2503-2758 3.57e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 3.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2503 AANQQAQRDLAECNEEIDKLAGRIRELEQALlndAEGKRSISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQ 2582
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEE---KALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2583 SKVDETRhcyhdnqreptQELSDALDLAQQSlrSKEQEVEAVVGQLETLQSELGLKevELKHLALQLEQLTNQNADHVNE 2662
Cdd:COG4942     97 AELEAQK-----------EELAELLRALYRL--GRQPPLALLLSPEDFLDAVRRLQ--YLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2663 LQEQIDALKENVSALAILNEEREEQSEAEepeeenfpSALIEEKNQEIDHLNAEIQRLEQELdntednKALEAELEDLRS 2742
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAAL--------EALKAERQKLLARLEKELAELAAEL------AELQQEAEELEA 227

                          250
                   ....*....|....*.
gi 1838138447 2743 QVEHLQSEVMRVRQDT 2758
Cdd:COG4942    228 LIARLEAEAAAAAERT 243
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 2842-3106 3.71e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.66  E-value: 3.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2842 KTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKR---------LTAEREKADKLQSVLTLKEAELDEVKAQKEGDA 2912
Cdd:pfam17380  323 KARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRelerirqeeIAMEISRMRELERLQMERQQKNERVRQELEAAR 402

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2913 EERKLSEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAE 2992
Cdd:pfam17380  403 KVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKE 482

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2993 LVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQ--LNEREASQEEAQKev 3070
Cdd:pfam17380  483 KRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQqeMEERRRIQEQMRK-- 560

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1838138447 3071 lthaeVTLAKADAALRQREAELARLRAEHQALKAEL 3106
Cdd:pfam17380  561 -----ATEERSRLEAMEREREMMRQIVESEKARAEY 591
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 535-1048 3.91e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 3.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  535 EQQFEQTDLEKELLNQQCGELRDELLLKDRDLNVLREEVIN---TAEELEEARSRWGQVTEELRQALWELEEEKEKKRLA 611
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREleeRLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  612 EEEMNLKAHEQDNLKSKLSALMEEREKEKAVLLTGKEAAETSLLvpaitpsEEEDELVGELKKKKQQDLLLSQQEIKQPA 691
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA-------ELAAQLEELEEAEEALLERLERLEEELEE 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  692 ISAEQILELRDDKPLQTLQVEAMVGQLETLQselglKEVELKHLALQLEQLTNQNADHVNDLQEQIDALKAQCEHLLLHL 771
Cdd:COG1196    426 LEEALAELEEEEEEEEEALEEAAEEEAELEE-----EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  772 EEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDRLQGELEKSLDSLDTAEQVKSElesqifcLKQNLAKL 851
Cdd:COG1196    501 ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY-------LKAAKAGR 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  852 EEAQAQTEQEREERRRKEEEMDDQIKKMEQVLEEELEQFESLLKAKDVELSEAKEKWEEESQEKETELLGVRHHLEEQRR 931
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEG 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  932 EREEEVKALLEKQVLAVEEETERLktshQQEIKDLMERHRQEISELNTHLESEQLKQQVNMEEEQKRQISFIKQVTEREH 1011
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEA----EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1838138447 1012 ERMLSELSAKHNEELTQLRTEVSLELRESMEAAHQAE 1048
Cdd:COG1196    730 LEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2289-2773 3.99e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.60  E-value: 3.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2289 AEKALLEESLQQKEVQEERLVEELEDLKVKLHQMQGLTAELDGLRLKHQELSEEHSLLLRQKEHLSA---GLGEREKALL 2365
Cdd:PRK03918   176 RRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEElekELESLEGSKR 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2366 AETERL--TQDRLDLQRQAEKDHKSLSLRLRALERDLEEKET------QDLETEQHHKTHNEDLNQRVQALEKQLKhDRQ 2437
Cdd:PRK03918   256 KLEEKIreLEERIEELKKEIEELEEKVKELKELKEKAEEYIKlsefyeEYLDELREIEKRLSRLEEEINGIEERIK-ELE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2438 FIEEQAVEREHERDEFQQEIRSLEAQLRqtasvdnKGHRFQDLVLQVESLQAIIKDKT-----EDHDSLIAANQQAQRDL 2512
Cdd:PRK03918   335 EKEERLEELKKKLKELEKRLEELEERHE-------LYEEAKAKKEELERLKKRLTGLTpekleKELEELEKAKEEIEEEI 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2513 AECNEEIDKLAGRIRELEQAL--LNDAEGK---------------------RSISQLEQELHRSKLREQELSQDKQALEq 2569
Cdd:PRK03918   408 SKITARIGELKKEIKELKKAIeeLKKAKGKcpvcgrelteehrkelleeytAELKRIEKELKEIEEKERKLRKELRELE- 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2570 QQLSNRLQISALQSKVDETRHCYHD-------------NQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELG 2636
Cdd:PRK03918   487 KVLKKESELIKLKELAEQLKELEEKlkkynleelekkaEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2637 LKEVELKHLALQLEQLTNQNADHVNE-LQEQIDALKENVSALAILNEEREEQSEAEEPEEEnfpsalIEEKNQEIDHLNA 2715
Cdd:PRK03918   567 ELEEELAELLKELEELGFESVEELEErLKELEPFYNEYLELKDAEKELEREEKELKKLEEE------LDKAFEELAETEK 640

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1838138447 2716 EIQRLEQELDNTEDNKAlEAELEDLRSQVEHLQSEVMRVRQDTQEEVERLHEVISTLQ 2773
Cdd:PRK03918   641 RLEELRKELEELEKKYS-EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLE 697
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 145-400 4.71e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.47  E-value: 4.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  145 LQEALASRDQVQLEAQSLAGQIQGLQRQLQQTSVEflriKSQSGAEVLNTRQPHGRCSQDADLNHKEAPSGSAAPETISc 224
Cdd:COG1196    227 AELLLLKLRELEAELEELEAELEELEAELEELEAE----LAELEAELEELRLELEELELELEEAQAEEYELLAELARLE- 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  225 vegfSTDTALEKLRVELEEERKNSQRIYAELALEMEKHQHVLSLLEKEKNSREEEQKEKEEQLQDLQMQFSLVQTQCLEM 304
Cdd:COG1196    302 ----QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  305 QqykEEKEKLNREVLELRKRLQEEADAERRLGEEVASSALRLQRQEEEMLRLKEEHREEVEGVRQLLEEREKELKFREEE 384
Cdd:COG1196    378 E---EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250
                   ....*....|....*.
gi 1838138447  385 VLGLKASKNRQNKAKA 400
Cdd:COG1196    455 EEEEEALLELLAELLE 470
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2594-2821 5.33e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 5.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2594 DNQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKEN 2673
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2674 VSALAILNEEREEQSEAEEPEEENFPSALIEEKNQEIDHLNAEIQRLEQELDNTEDNKA----LEAELEDLRSQVEHLQS 2749
Cdd:COG3883     99 GGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAeleaLKAELEAAKAELEAQQA 178

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1838138447 2750 EVMRVRQDTQEEVERLHEVISTLQAELATLGPNLHEVSDSQDGDSINPSPAPSPEPDNYTVQEQARRGGANS 2821
Cdd:COG3883    179 EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAG 250
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2485-3126 6.35e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 6.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2485 ESLQAIIKdKTEDHDSLIAANQQaqrDLAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSKLREQELSQDK 2564
Cdd:PRK03918   179 ERLEKFIK-RTENIEELIKEKEK---ELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSK 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2565 QALEQQQLSNRLQISALQSKVDETRHCYHD-NQREPTQELSDALDLAQQSLRSKEQEVEAVVGQLETLQSELGLKEVELK 2643
Cdd:PRK03918   255 RKLEEKIRELEERIEELKKEIEELEEKVKElKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2644 HLALQLEQLTNQnadhVNELQEQIDALKENVSALAILNEEREEQSEAEEPEEENFPsaliEEKNQEIDHLNAEIQRLEQE 2723
Cdd:PRK03918   335 EKEERLEELKKK----LKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP----EKLEKELEELEKAKEEIEEE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2724 LDNTEDNKA-LEAELEDLRSQVEHLQSEVMRV----RQDTQEEVERL----HEVISTLQAELATLGPNLHEVSdsqdgds 2794
Cdd:PRK03918   407 ISKITARIGeLKKEIKELKKAIEELKKAKGKCpvcgRELTEEHRKELleeyTAELKRIEKELKEIEEKERKLR------- 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2795 inpspapspepDNYTVQEQARRGGANSLKQELSLSYSASSHSLRSRFKTlqSQLEAAAAEKEGLERLLLTQEEEYRGhge 2874
Cdd:PRK03918   480 -----------KELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNL--EELEKKAEEYEKLKEKLIKLKGEIKS--- 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2875 efgkrLTAEREKADKLQSVLTLKEAELDEVKAQK---EGDAEERKLSEEVNDKVQNQEMSTLRDKNLHLNSLIAEVQKKE 2951
Cdd:PRK03918   544 -----LKKELEKLEELKKKLAELEKKLDELEEELaelLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREE 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2952 QERVTEMDTLKTKEQEMEMetevlretsltLERQVQEMRAELVDMEELVDEERIKiktlktvkgELSAERETLRRREGKL 3031
Cdd:PRK03918   619 KELKKLEEELDKAFEELAE-----------TEKRLEELRKELEELEKKYSEEEYE---------ELREEYLELSRELAGL 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3032 QEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKevlthaevtlakadaaLRQREAELARLRAEHQALKAELTEvkQ 3111
Cdd:PRK03918   679 RAELEELEKRREEIKKTLEKLKEELEEREKAKKELEK----------------LEKALERVEELREKVKKYKALLKE--R 740

                          650
                   ....*....|....*
gi 1838138447 3112 GLSTSTERAEKLHEE 3126
Cdd:PRK03918   741 ALSKVGEIASEIFEE 755
PRK13729 PRK13729
conjugal transfer pilus assembly protein TraB; Provisional
 2711-2805 7.42e-04

conjugal transfer pilus assembly protein TraB; Provisional


Pssm-ID: 184281 [Multi-domain]  Cd Length: 475  Bit Score: 45.58  E-value: 7.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2711 DHLNAEIQrleqeldntEDNKALEAELEDLRSQVEHLQSEvmrvRQDTQEEVERLHEVISTLQAELATLGPNLHEVSDSQ 2790
Cdd:PRK13729    68 QHATTEMQ---------VTAAQMQKQYEEIRRELDVLNKQ----RGDDQRRIEKLGQDNAALAEQVKALGANPVTATGEP 134

                           90
                   ....*....|....*
gi 1838138447 2791 DGDSINPSPAPSPEP 2805
Cdd:PRK13729   135 VPQMPASPPGPEGEP 149
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2703-3041 7.57e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 7.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2703 IEEKNQEIDHLNAEIQRLEQELDNTEDNKALEAELEDLRSQVEHLQSEVMRV-RQDTQEEVERLHEVISTLQAELATLGP 2781
Cdd:TIGR02169  186 IERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERqKEAIERQLASLEEELEKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2782 NLHEVSdsQDGDSINPSPAPSPEPDNYTVQEQARRGGAN-SLKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEGLER 2860
Cdd:TIGR02169  266 RLEEIE--QLLEELNKKIKDLGEEEQLRVKEKIGELEAEiASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELER 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2861 LLltqeeeyrghgEEFGKRLTAEREKADKLQSVLTLKEAELDEVkaqkegDAEERKLSEEVNDKVQNQEMstlrdknlhl 2940
Cdd:TIGR02169  344 EI-----------EEERKRRDKLTEEYAELKEELEDLRAELEEV------DKEFAETRDELKDYREKLEK---------- 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2941 nsliaeVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAE 3020
Cdd:TIGR02169  397 ------LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340
                   ....*....|....*....|.
gi 1838138447 3021 RETLRRREGKLQEEIENLRQE 3041
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRE 491
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2387-2775 7.64e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 7.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2387 KSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLNQRVQALEK------QLKHDRQFIEEQAVEREHERDEFQQEIRSL 2460
Cdd:TIGR04523  207 KKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNtqtqlnQLKDEQNKIKKQLSEKQKELEQNNKKIKEL 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2461 EAQLRQTASvdnkghrfQDLVLQVESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALLN----D 2536
Cdd:TIGR04523  287 EKQLNQLKS--------EISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNseseN 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2537 AEGKRSISQLEQELHRSKLREQELSQDKQALEQQqlsnrlqISALQSKVDetrhcyhdNQREPTQELSDALDLAQQSLRS 2616
Cdd:TIGR04523  359 SEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ-------INDLESKIQ--------NQEKLNQQKDEQIKKLQQEKEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2617 KEQEVEAVVGQLETLQSELglkevelkhlalqlEQLTNQNAD---HVNELQEQIDALKENVSALAILNEEREEQSEAEEP 2693
Cdd:TIGR04523  424 LEKEIERLKETIIKNNSEI--------------KDLTNQDSVkelIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2694 EeenfpsalIEEKNQEIDHLNAEIQRLEQELDNTEDNKAL---------------EAELEDLRSQVEHLQSEVMR----- 2753
Cdd:TIGR04523  490 E--------LKSKEKELKKLNEEKKELEEKVKDLTKKISSlkekieklesekkekESKISDLEDELNKDDFELKKenlek 561

                          410       420
                   ....*....|....*....|..
gi 1838138447 2754 VRQDTQEEVERLHEVISTLQAE 2775
Cdd:TIGR04523  562 EIDEKNKEIEELKQTQKSLKKK 583
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3574-3873 8.11e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 8.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3574 KDREKEERREALHVSSEQQRSEVMALKGLVEQERVACSNLRREL-----QIEQSRSEL--LEKRLDDTQKELGDerqlsa 3646
Cdd:TIGR02168  219 KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELqeleeKLEELRLEVseLEEEIEELQKELYA------ 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3647 nqkelKLQDKTRLERLLAEAESRLAEIHSTLAEahrkVDEERERYSRQVDELsrrhEADATRDRKFISDMRAQLEQERRQ 3726
Cdd:TIGR02168  293 -----LANEISRLEQQKQILRERLANLERQLEE----LEAQLEELESKLDEL----AEELAELEEKLEELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3727 GEELAAVMNKLRAELLQSRSKWEEEdRARRAELQREKEAAIQQRVAVETLKEQkqetccaLEMERARSTQqgvELTELKE 3806
Cdd:TIGR02168  360 LEELEAELEELESRLEELEEQLETL-RSKVAQLELQIASLNNEIERLEARLER-------LEDRRERLQQ---EIEELLK 428

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1838138447 3807 KLHLIKDKEREREEQWERERRKGRQEQMER-ERRQERTNDKLCELEMLRQQDQQRMQELQHTLVELER 3873
Cdd:TIGR02168  429 KLEEAELKELQAELEELEEELEELQEELERlEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 534-1144 8.39e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 8.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  534 SEQQFEQTDLEKELLNQQCGELRDELLLKDRDLNVLREEVINTAEELEEARSRWGQVTEELRQALWELEEEKEKKRLAEE 613
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  614 EMNLKAHEQDNLKSKLSALMEEREKEKAVlltgKEAAETSLLVPAITPSEEEDELVGELKKKKQQDLLLSQQEIKQPAIS 693
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQE----IEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  694 AEQILELRDDKPLQTLQVEAMVGQLETLQSEL-----GLKEVELKhlALQLEQLTNQNADHVN-----------DLQEQI 757
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLERLQENLegfseGVKALLKN--QSGLSGILGVLSELISvdegyeaaieaALGGRL 547

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  758 DAL----KAQCEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDRLQGELEKSL--------- 824
Cdd:TIGR02168  548 QAVvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALsyllggvlv 627

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  825 -DSLDTAEQVKSEL---------------------------ESQIFCLKQNLAKLEEAQAQTEQEREERRRKEEEMDDQI 876
Cdd:TIGR02168  628 vDDLDNALELAKKLrpgyrivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  877 KKMEQVLEEELEQFESllkaKDVELSEAKEKWEEESQEKETELLGVRHHLEEQRREREEEVKALLEKQVLAVE-EETERL 955
Cdd:TIGR02168  708 EELEEELEQLRKELEE----LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEElAEAEAE 783

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  956 KTSHQQEIKDLMERH---RQEISELN---THLESEQLKQQVNMEEEQKRQISFIKQVTErehermLSELSAKHNEELTQL 1029
Cdd:TIGR02168  784 IEELEAQIEQLKEELkalREALDELRaelTLLNEEAANLRERLESLERRIAATERRLED------LEEQIEELSEDIESL 857

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1030 RTEVSlELRESMEaAHQAELLQHQVQKRSELEAM---RLSLTNAHVSQLEQESALTEAQGSPRDTFAQEIALLKAQHQAE 1106
Cdd:TIGR02168  858 AAEIE-ELEELIE-ELESELEALLNERASLEEALallRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1838138447 1107 LDHIRQQEKLRELQQQPMNDLQQQWETLVAQERAAMEE 1144
Cdd:TIGR02168  936 VRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR 973
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2450-2642 8.96e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 8.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2450 RDEFQQEIRSLEAQLRQTASvdnkghrfqdlvlQVESLQAIIKDKTEDHDSL--IAANQQAQRDLAECNEEIDKLAGRIR 2527
Cdd:COG4913    612 LAALEAELAELEEELAEAEE-------------RLEALEAELDALQERREALqrLAEYSWDEIDVASAEREIAELEAELE 678

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2528 ELEQAllNDAegkrsISQLEQELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHCYHDNQREPTQELSDAL 2607
Cdd:COG4913    679 RLDAS--SDD-----LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1838138447 2608 D--LAQQSLRSKEQEV-EAVVGQLETLQSELGLKEVEL 2642
Cdd:COG4913    752 EerFAAALGDAVERELrENLEERIDALRARLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1219-1474 9.04e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 9.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1219 QELEAELEQACADRDAAARSLEELMSSHKAVlqEREQQALHLEEKEEQLKQEVLRLQEERSSLKKnseqevgqlwtQLES 1298
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDAL--QERREALQRLAEYSWDEIDVASAEREIAELEA-----------ELER 679

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1299 MRTSRQELGELKEQLLARSARVDDIERLKTEFNEQKREIKEQNEAELESLRRYFEQRLRATEEGHREEIALLQLRLvERA 1378
Cdd:COG4913    680 LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF-AAA 758

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1379 LEESVIRTADDSFSSiSQGQAEEEKDHLFSDAVFKLEKHKEALDNVSLQLEEkhsmDLSYLQssmslSFKEELQQVQSDI 1458
Cdd:COG4913    759 LGDAVERELRENLEE-RIDALRARLNRAEEELERAMRAFNREWPAETADLDA----DLESLP-----EYLALLDRLEEDG 828

                          250
                   ....*....|....*.
gi 1838138447 1459 TDQYYEELQELKTRHA 1474
Cdd:COG4913    829 LPEYEERFKELLNENS 844
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 554-857 9.99e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 9.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  554 ELRDELLLKDRDLNVLREEVINTAEELEEARSRWGQVTEELRQALWELEEEKEKKRLAEEEMNLKAHEQDNLKSKLSALM 633
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  634 EEREKEKAvlltgkeaaetsllvpaitpseEEDELVGELKKKkQQDLLLSQQEIKQP--AISAEQILELRDDKPLQTLQV 711
Cdd:TIGR02169  751 QEIENVKS----------------------ELKELEARIEEL-EEDLHKLEEALNDLeaRLSHSRIPEIQAELSKLEEEV 807

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  712 EAMVGQLETLQSELGLKEVELKhlalQLEQLTNQNADHVNDLQEQIDALKAQCEHLLLHLEEMTTTHKTTAALIDEKTTE 791
Cdd:TIGR02169  808 SRIEARLREIEQKLNRLTLEKE----YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1838138447  792 LDRTSKELERTRAQVVNVQTEVDRLQGELEKsldsldtAEQVKSELESQIFCLKQNLAKLEEAQAQ 857
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEK-------KRKRLSELKAKLEALEEELSEIEDPKGE 942
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2858-3064 1.02e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2858 LERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERKLSEEVNDKVQNQ-EMSTLRDK 2936
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARaELAEAEAR 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2937 NLHLNSLIAEVQKKEQERVT--EMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEErikiktLKTVK 3014
Cdd:COG3206    242 LAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE------AQRIL 315

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3015 GELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQE 3064
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2402-3161 1.12e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.42  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2402 EKETQDLETEQHHKTHNEDlnqRVQALEKQLKHDRQFIEEqaveREHERDEFQQEIRSLEAQLRQTASVDNKGHRFQDLV 2481
Cdd:TIGR00606  206 QMELKYLKQYKEKACEIRD---QITSKEAQLESSREIVKS----YENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRK 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2482 LQVESLQAIIKDK-------TEDHDSLIAANQQA-----QRDLAECNEEIDKLAGRIRELEQALlNDAEGKRSISQLEQE 2549
Cdd:TIGR00606  279 KQMEKDNSELELKmekvfqgTDEQLNDLYHNHQRtvrekERELVDCQRELEKLNKERRLLNQEK-TELLVEQGRLQLQAD 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2550 LHRSKLReqelsqdKQALEQQQLSNRLQISALQSKVDETRHC--YHDNQREPTQ-----------ELSDALDLAQQSLRS 2616
Cdd:TIGR00606  358 RHQEHIR-------ARDSLIQSLATRLELDGFERGPFSERQIknFHTLVIERQEdeaktaaqlcaDLQSKERLKQEQADE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2617 KEQEVEAVVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNELQEQIDALKEnvsaLAILNEEREEQSEAEEPEEE 2696
Cdd:TIGR00606  431 IRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERE----LSKAEKNSLTETLKKEVKSL 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2697 NFPSALIEEKNQEIDHLNAEIQRLEQELDNTE--------------------------------DNKALEAELEDLRSQV 2744
Cdd:TIGR00606  507 QNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltkdkmdkdeqirkiksrhsdeltsllgyfpNKKQLEDWLHSKSKEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2745 EHLQSEVMRVRQDTQEEVERLHEV---ISTLQAELATLGPNLHEVSDSQDGDSINPSPAPSPEPDNYTVQEQARRGGANS 2821
Cdd:TIGR00606  587 NQTRDRLAKLNKELASLEQNKNHInneLESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2822 LKQELSLSYSASSHSLRSRFKTLQSQLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAEL 2901
Cdd:TIGR00606  667 QFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEI 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2902 DEVKAQKegdaeeRKLSEEVNdkvqnQEMSTLRDKNLHLNSLIAEVQKKE--QERVTEMDTL--KTKEQEMEMETEVLRE 2977
Cdd:TIGR00606  747 PELRNKL------QKVNRDIQ-----RLKNDIEEQETLLGTIMPEEESAKvcLTDVTIMERFqmELKDVERKIAQQAAKL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2978 TSLTLERQVQEMRAELVDMEE--------------LVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEAT 3043
Cdd:TIGR00606  816 QGSDLDRTVQQVNQEKQEKQHeldtvvskielnrkLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELST 895

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3044 SMRACIQELTvQLNEREASQEEAQKEVLTHAEVTLAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKL 3123
Cdd:TIGR00606  896 EVQSLIREIK-DAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQ 974

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1838138447 3124 HEEGQTKDRALLN-LETDNQRLKAQLRALQEDLAVQEEE 3161
Cdd:TIGR00606  975 KETELNTVNAQLEeCEKHQEKINEDMRLMRQDIDTQKIQ 1013
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 675-1316 1.13e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.21  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  675 KKQQDLLLSQQEIKQPAISAEQILELRDDKPLQTLqVEAMVGQLETLQSELGLKEVELKHLALQLEQLTNQNADHVNDLQ 754
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEK-RDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQ 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  755 EQIDALKAQCEHLLLHLEEMTTTH-KTTAALIDEKTTELDRTSKELERTRAQVVNVQTEVDRLQGELEKSLDSLDTA--- 830
Cdd:pfam12128  347 EQLPSWQSELENLEERLKALTGKHqDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESElre 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  831 --EQVKSELESQIFCLKQNLAKLEEAQAQTEQEREERRRKEEEmDDQIKKMEQVLEEELEQFESLLKAKDVeLSEAKEKW 908
Cdd:pfam12128  427 qlEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENF-DERIERAREEQEAANAEVERLQSELRQ-ARKRRDQA 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  909 EEESQEKETELLGVRHHLEEQRREREEEVKALLE---KQVLAVEEETERLKTSHQQEIKDL-----MERHRQEIS--ELN 978
Cdd:pfam12128  505 SEALRQASRRLEERQSALDELELQLFPQAGTLLHflrKEAPDWEQSIGKVISPELLHRTDLdpevwDGSVGGELNlyGVK 584

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  979 THLESEQLKQQVNMEEEQKRQISFIKQVTEREHERmlselSAKHNEELTQLRTEVslelresmEAAHQAELLQHQVQKRS 1058
Cdd:pfam12128  585 LDLKRIDVPEWAASEEELRERLDKAEEALQSAREK-----QAAAEEQLVQANGEL--------EKASREETFARTALKNA 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1059 ELEAMRlsLTNAHVS-QLEQESALTEAQ---GSPRDTFAQEIALLKAQHQAELDHirQQEKLRELQQQPMNDLQQQWETL 1134
Cdd:pfam12128  652 RLDLRR--LFDEKQSeKDKKNKALAERKdsaNERLNSLEAQLKQLDKKHQAWLEE--QKEQKREARTEKQAYWQVVEGAL 727

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1135 VAQ------ERAAMEEEQAKDIQALRSQWDKNAESRESNLQMFLsemqnSLTATQTDLTQTLKALSQTQAELQRSGAKLQ 1208
Cdd:pfam12128  728 DAQlallkaAIAARRSGAKAELKALETWYKRDLASLGVDPDVIA-----KLKREIRTLERKIERIAVRRQEVLRYFDWYQ 802

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1209 ELQTSSKDMNQELEAELEQACADRDAAARSLEELMSSHKAVLqEREQQALHLEEKEEQLKQEVLRLQEERSS---LKKNS 1285
Cdd:pfam12128  803 ETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKL-EMERKASEKQQVRLSENLRGLRCEMSKLAtlkEDANS 881

                          650       660       670
                   ....*....|....*....|....*....|....
gi 1838138447 1286 EQ---EVGQLWTQLESMRTSRQELGELKEQLLAR 1316
Cdd:pfam12128  882 EQaqgSIGERLAQLEDLKLKRDYLSESVKKYVEH 915
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 2401-2666 1.29e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.04  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2401 EEKETQDLETEQHHKTHNEdlNQRVQALEKQLK--HDRQFIEEQAVEREHERDEFQQEIRSLEAQL---RQTASVDNKGH 2475
Cdd:PRK10929    25 EKQITQELEQAKAAKTPAQ--AEIVEALQSALNwlEERKGSLERAKQYQQVIDNFPKLSAELRQQLnneRDEPRSVPPNM 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2476 RFQDL---VLQVESlQAIIK--------DKT-EDHDSLIAANQQ---AQRDLAECNEEIDKLAGRIRELEQAllndaegK 2540
Cdd:PRK10929   103 STDALeqeILQVSS-QLLEKsrqaqqeqDRArEISDSLSQLPQQqteARRQLNEIERRLQTLGTPNTPLAQA-------Q 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2541 RSISQLEQELHRSKLREQELSqdkqaleqqQLS--NRLQISALQSKVDETRHcyhdnqreptqelsDALDLAQQSLRS-- 2616
Cdd:PRK10929   175 LTALQAESAALKALVDELELA---------QLSanNRQELARLRSELAKKRS--------------QQLDAYLQALRNql 231

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1838138447 2617 ---KEQEVEAVVGQLETLQSELG-LKEVELKHLAL--QLEQLTNQNADHVNELQEQ 2666
Cdd:PRK10929   232 nsqRQREAERALESTELLAEQSGdLPKSIVAQFKInrELSQALNQQAQRMDLIASQ 287
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
3550-3762 1.30e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3550 LRREQVRVQELQQQLEQERALSQRKDREKEERREALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEK 3629
Cdd:COG4913    237 LERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3630 RLDDTQKELgdeRQLSANQKELKLQDKTRLERLLAEAESRLAEI-------HSTLAEAHRKVDEERERYSRQVDELsRRH 3702
Cdd:COG4913    317 RLDALREEL---DELEAQIRGNGGDRLEQLEREIERLERELEERerrrarlEALLAALGLPLPASAEEFAALRAEA-AAL 392

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3703 EADATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRSKWEEEDRARRAELQRE 3762
Cdd:COG4913    393 LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1352-2114 1.31e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.11  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1352 FEQRLRATEEGHREEIALLQLRLVERALEESVIRTADDSFSSIS--QGQAEEEKDHLFSDAVFKLEKHK----EALDNVS 1425
Cdd:pfam15921   90 LQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRrrESQSQEDLRNQLQNTVHELEAAKclkeDMLEDSN 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1426 LQLEEKHSMDLS-----------------------YLQSSMSLSFKEELQQVQSDITDQYYEELQELKTR---HAMELEK 1479
Cdd:pfam15921  170 TQIEQLRKMMLShegvlqeirsilvdfeeasgkkiYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRifpVEDQLEA 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1480 LRAKlSDHHVKELTRAHLEAARQVEVEVEQRMWCLTEELQSRMTIIHTLDSKLAALSKQhdaevQRNTQKLkqeFAGELV 1559
Cdd:pfam15921  250 LKSE-SQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQ-----ARNQNSM---YMRQLS 320

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1560 HLEEALKQEREDVQEERKRWREELQEKHQaELSALRSELDrEMESERTRLEKELHEEKERLKTLQAALDNDESpqvlivR 1639
Cdd:pfam15921  321 DLESTVSQLRSELREAKRMYEDKIEELEK-QLVLANSELT-EARTERDQFSQESGNLDDQLQKLLADLHKREK------E 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1640 QRLEAQYDGELQRAKSCMATEVKELTARLQEQGEErlhqaqerlhgekaaleqslAQKYEASLAELKSKHQSELEHERAA 1719
Cdd:pfam15921  393 LSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNME--------------------VQRLEALLKAMKSECQGQMERQMAA 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1720 LLNKERDTldakhkAQLDSLSAshrdQLTATaAELKSKHSAELVALEAALDSKRKAdIESLEGVLKETNQAqLEASEAEL 1799
Cdd:pfam15921  453 IQGKNESL------EKVSSLTA----QLEST-KEMLRKVVEELTAKKMTLESSERT-VSDLTASLQEKERA-IEATNAEI 519

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1800 TRkhQEEKDELEMRMLGNMDTlESTYLKEVQAlrdeiiqleerHCRGLNLQKSEHRQVLerhasEQLSIREELRKELAQL 1879
Cdd:pfam15921  520 TK--LRSRVDLKLQELQHLKN-EGDHLRNVQT-----------ECEALKLQMAEKDKVI-----EILRQQIENMTQLVGQ 580

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1880 HIEKFSAMAVElshvhkteltaqkealdtdhckaletlKKQVLEVEQQHSLALQELsqtctadkeqllaqqqLQLQDLRG 1959
Cdd:pfam15921  581 HGRTAGAMQVE---------------------------KAQLEKEINDRRLELQEF----------------KILKDKKD 617

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1960 VSARELEACRRELEEESSRQRQHFLEEVELLKVQSEERLQdRINRLKTEFEEQKE--ARLEDLKRSFTSEQEEKERSYTD 2037
Cdd:pfam15921  618 AKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQ-LLNEVKTSRNELNSlsEDYEVLKRNFRNKSEEMETTTNK 696

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2038 KMSQLTIQLQQLDTVVAQLRAEVGC----------LQGELEGKRSEMETLDTLLQRRQRETQEGGNLLKMLtddlqagKE 2107
Cdd:pfam15921  697 LKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFL-------KE 769


                   ....*..
gi 1838138447 2108 ERRKLNQ 2114
Cdd:pfam15921  770 EKNKLSQ 776
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 2325-2652 1.33e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2325 LTAELDGLRLKHQELSEEHSLLLRQKEHLSAGLGerekallaeterlTQDRLDLQRQAEKDHKSLSLRLRALERDLEEKE 2404
Cdd:COG3096    790 LRAERDELAEQYAKASFDVQKLQRLHQAFSQFVG-------------GHLAVAFAPDPEAELAALRQRRSELERELAQHR 856

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2405 tqdlETEQHHKTHNEDLNQRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQtasvdnkghrFQDLVLQV 2484
Cdd:COG3096    857 ----AQEQQLRQQLDQLKEQLQLLNKLLPQANLLADETLADRLEELREELDAAQEAQAFIQQ----------HGKALAQL 922

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2485 ESLQAIIKDKTEDHDSLIAANQQAQRDLAECNEEIDKLAGRIRELEQALLNDAEGKRSISQLEQELHRSKLR--EQELSQ 2562
Cdd:COG3096    923 EPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLEqaEEARRE 1002

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2563 DKQALEQQQlSNRLQISALQSKVDETRHCYHDNQREPTQEL--------SDALDLAQQSLRSKEQEVEAVVGQLETLQSE 2634
Cdd:COG3096   1003 AREQLRQAQ-AQYSQYNQVLASLKSSRDAKQQTLQELEQELeelgvqadAEAEERARIRRDELHEELSQNRSRRSQLEKQ 1081

                          330
                   ....*....|....*...
gi 1838138447 2635 LGLKEVELKHLALQLEQL 2652
Cdd:COG3096   1082 LTRCEAEMDSLQKRLRKA 1099
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2256-2463 1.64e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2256 HKILLEQLDQEAKLK--SELQLEYHKTEGLLEG--YVAEKALLEESLQQKEVQEERLVEELEDLkvklhqmQGLTAELDG 2331
Cdd:COG4913    241 HEALEDAREQIELLEpiRELAERYAAARERLAEleYLRAALRLWFAQRRLELLEAELEELRAEL-------ARLEAELER 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2332 LRLKHQELSEEHSLLLRQkeHLSAGlGEREKALLAETERLTQDRLDLQRQAEKdhksLSLRLRALERDLEEKETQDLETE 2411
Cdd:COG4913    314 LEARLDALREELDELEAQ--IRGNG-GDRLEQLEREIERLERELEERERRRAR----LEALLAALGLPLPASAEEFAALR 386

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1838138447 2412 QHHKTHNEDLNQRVQALEKQLkhDRQFIEEQAVEREHerDEFQQEIRSLEAQ 2463
Cdd:COG4913    387 AEAAALLEALEEELEALEEAL--AEAEAALRDLRREL--RELEAEIASLERR 434
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2853-3092 1.70e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2853 AEKEGLERLLlTQEEEYRGHGEEFGKRLTAEREKADKLQSVLTLKEAELDEVKAQKEGDAEERKLSEEVNDKVQ--NQEM 2930
Cdd:PRK03918   176 RRIERLEKFI-KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELEslEGSK 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2931 STLRDKNLHLNSLIAEVQKKEQE---RVTEMDTLKTKEQE-------MEMETEVLRETSLTLERQVQEMRAELVDMEELV 3000
Cdd:PRK03918   255 RKLEEKIRELEERIEELKKEIEEleeKVKELKELKEKAEEyiklsefYEEYLDELREIEKRLSRLEEEINGIEERIKELE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3001 DEERiKIKTLKTVKGELSAERETLRRREgKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEVLTHAEVTLAK 3080
Cdd:PRK03918   335 EKEE-RLEELKKKLKELEKRLEELEERH-ELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA 412

                          250
                   ....*....|..
gi 1838138447 3081 ADAALRQREAEL 3092
Cdd:PRK03918   413 RIGELKKEIKEL 424
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 108-384 1.83e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  108 EDIEEEELIALTGKEQLKQLQEAVEKRneiIARLSSNLQEALASRDQVQLEAQSLAGQIQGLQRQLQQTSVEFLRIKsqs 187
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKD---LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE--- 781

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  188 gAEVLNTRQPHGRCSQDADLNHKEAPSGSAAPETIScVEGFSTDTALEKLRVELEEERKNSQriyaELALEMEKHQHVLS 267
Cdd:TIGR02168  782 -AEIEELEAQIEQLKEELKALREALDELRAELTLLN-EEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  268 LLEKEKNSREEEQKEKEEQLQDLQMQFSLVQTQcleMQQYKEEKEKLNREVLELRKRLQEEADAERRLGEEVASSALRLQ 347
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEA---LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1838138447  348 RQEEEMLRLKEEHREEVEGVRQLLEEREKELKFREEE 384
Cdd:TIGR02168  933 GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 3509-3747 2.05e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 2.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3509 SQLRAELEESQKQLKcahdTQQEHKNKMQSVRVAVAEGEEALRREQVRVQELQQQLEQERALSQRKDREKEERREALHVS 3588
Cdd:COG4942     23 AEAEAELEQLQQEIA----ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3589 SEQQRSEvmalkgLVEQERVACSNLRR---ELQIEQSRSELLEKRLDDTqKELGDERQLSANQKELKLQDKTRLERLLAE 3665
Cdd:COG4942     99 LEAQKEE------LAELLRALYRLGRQpplALLLSPEDFLDAVRRLQYL-KYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3666 AESRLAEIHSTLAEAHRKVDEERERYSRQVDELSRRHEADatrdrkfisdmRAQLEQERRQGEELAAVMNKLRAELLQSR 3745
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAEL-----------AAELAELQQEAEELEALIARLEAEAAAAA 240


                   ..
gi 1838138447 3746 SK 3747
Cdd:COG4942    241 ER 242
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 3552-3880 2.11e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 44.34  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3552 REQVRVQELQQQLEQERALSQRKDREKEERREALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQsrsELLEKRL 3631
Cdd:pfam17380  279 QHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERER---ELERIRQ 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3632 DDTQKELGDERQlsaNQKELKLQDKTRLERLLAEAESRLAEIHSTLaEAHRKVDEERERYSRQVDELSRRHEADATRDRK 3711
Cdd:pfam17380  356 EERKRELERIRQ---EEIAMEISRMRELERLQMERQQKNERVRQEL-EAARKVKILEEERQRKIQQQKVEMEQIRAEQEE 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3712 fisdmrAQLEQERRQGEELAAVMNKLRAELLQSRSKWE----EEDRARRAELQREKEAAIQQRVAVETLKEQKQETccal 3787
Cdd:pfam17380  432 ------ARQREVRRLEEERAREMERVRLEEQERQQQVErlrqQEEERKRKKLELEKEKRDRKRAEEQRRKILEKEL---- 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3788 eMERARSTQQGVELTELKEKLHLIKDKEREREEQWERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQHT 3867
Cdd:pfam17380  502 -EERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQ 580

                          330
                   ....*....|...
gi 1838138447 3868 LVELEREEKEMSA 3880
Cdd:pfam17380  581 IVESEKARAEYEA 593
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
3581-3773 2.14e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3581 RREALHVSSEQQRSEVMALKGLVEQERVAcsnLRRELQIEQSRSELLEKRLDDTQKELGDERQLSANQKelKLQDKTRLE 3660
Cdd:COG3206    202 RQKNGLVDLSEEAKLLLQQLSELESQLAE---ARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQ--LRAQLAELE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3661 RLLAEAESRLAEIHSTLAEAHRKVDEERERYSRQVDELSRRHEADATRDRKFISDMRAQLEQERRQgeelAAVMNKLRAE 3740
Cdd:COG3206    277 AELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEAR----LAELPELEAE 352

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1838138447 3741 LLQSRSKWEEEDRARRAELQREKEAAIQQRVAV 3773
Cdd:COG3206    353 LRRLEREVEVARELYESLLQRLEEARLAEALTV 385
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2344-2570 2.23e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2344 SLLLRQKEHLSAGLGEREKALLAETERLTQDRLDLQRQAEKDHKSLSLRLRALERDLEEKETQDLETEQHHKTHNEDLNQ 2423
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2424 ---RVQALEKQLKHDRQFIEEQAvereheRDEFQQEIRSLEAQLRQTASVDNKGHRFQDLVLQVESLQAIIKDKTEDHDS 2500
Cdd:COG4942     88 lekEIAELRAELEAQKEELAELL------RALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2501 LIAANQQAQRDLAECNEEIDKLAGRIRELEQALlndAEGKRSISQLEQELHRSKLREQELSQDKQALEQQ 2570
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALK---AERQKLLARLEKELAELAAELAELQQEAEELEAL 228
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2949-3131 2.34e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2949 KKEQERVTEMDTLKTKEQEMEMETEVLREtsltLERQVQEMRAELVDMEELVDEERIKIKTLKTVKG--ELSAERETLRR 3026
Cdd:COG4717     64 RKPELNLKELKELEEELKEAEEKEEEYAE----LQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEA 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3027 REGKLQEEIENLRQEATSmracIQELTVQLNEREASQEEAQKEVLTHAEVTLAKADAALRQREAELARLRAEHQALKAEL 3106
Cdd:COG4717    140 ELAELPERLEELEERLEE----LRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEEL 215

                          170       180
                   ....*....|....*....|....*
gi 1838138447 3107 TEVKQGLSTSTERAEKLHEEGQTKD 3131
Cdd:COG4717    216 EEAQEELEELEEELEQLENELEAAA 240
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 3015-3155 2.47e-03

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 43.21  E-value: 2.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3015 GELSAERETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEreasQEEAQKEVLTHAEVTLAKADAALRQREAELAR 3094
Cdd:pfam09787   43 TALTLELEELRQERDLLREEIQKLRGQIQQLRTELQELEAQQQE----EAESSREQLQELEEQLATERSARREAEAELER 118

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1838138447 3095 LRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDL 3155
Cdd:pfam09787  119 LQEELRYLEEELRRSKATLQSRIKDREAEIEKLRNQLTSKSQSSSSQSELENRLHQLTETL 179
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 941-1600 2.55e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  941 LEKQVLAVEEETERLKT---SHQQEIKDL---MERHRQEISELNTHLES-----EQLKQQVNMEEEQKRQISFIKQVTER 1009
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKelyALANEISRLeqqKQILRERLANLERQLEEleaqlEELESKLDELAEELAELEEKLEELKE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1010 EHERMLSELSAKHN-------------EELTQLRTEVSLELRE---------------SMEAAHQAELLQHQVQKRSELE 1061
Cdd:TIGR02168  352 ELESLEAELEELEAeleelesrleeleEQLETLRSKVAQLELQiaslnneierlearlERLEDRRERLQQEIEELLKKLE 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1062 AMRLSLTNAHVSQLEQESALTEAQGSPRDTFAQEIALLKAQHQAELDHIRQQEKLRELQQQPMNDLQQQWETLVAQERAA 1141
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAL 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1142 MEE-EQAKDIQALRSQWDKNAESRESNLQMFLSE-MQNSLTATQTDLTQTLKALSQTQAelqrSGAKLQELQTSSKDMNQ 1219
Cdd:TIGR02168  512 LKNqSGLSGILGVLSELISVDEGYEAAIEAALGGrLQAVVVENLNAAKKAIAFLKQNEL----GRVTFLPLDSIKGTEIQ 587

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1220 ELEAELEQACADRDAAARSLEELMSSHKAVLQ---------EREQQALHLEEKEEQLKQEVL----RLQEERSSLKKNSE 1286
Cdd:TIGR02168  588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRIVTldgdLVRPGGVITGGSAK 667

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1287 QEVGQLWTQLEsMRTSRQELGELKEQLLARSARVDDIERLKTEFNEQKREIKEQNEAE--LESLRRYFEQRLRATEEGHR 1364
Cdd:TIGR02168  668 TNSSILERRRE-IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELsrQISALRKDLARLEAEVEQLE 746

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1365 EEIALLQLRLVERALEESVIRTADDSFSSISQgQAEEEKDHLFSDavfkLEKHKEALDNVSLQLEEKHsMDLSYLQSSM- 1443
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELA-EAEAEIEELEAQ----IEQLKEELKALREALDELR-AELTLLNEEAa 820

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1444 SLSFKEELQQVQSDITDQYYEELQELKTRHAMELEKLRAKLSDhhvKELTRAHLEAARQVEVE----VEQRMWCLTEELQ 1519
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE---LEELIEELESELEALLNerasLEEALALLRSELE 897

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1520 SRMTIIHTLDSKLAALSKQHD------AEVQRNTQKLKQEFAGELVHLEEALKQEREDVqEERKRWREELQEKHQAELSA 1593
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEelreklAQLELRLEGLEVRIDNLQERLSEEYSLTLEEA-EALENKIEDDEEEARRRLKR 976


                   ....*..
gi 1838138447 1594 LRSELDR 1600
Cdd:TIGR02168  977 LENKIKE 983
PRK11281 PRK11281
mechanosensitive channel MscK;
1095-1347 2.56e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 2.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1095 EIALLKAQHQAELDHIRQQEKlrelQQQPMNDLQQQWETLVAQERAAMEEeqakdIQALRSQWDKNAESRESNLQmfLSE 1174
Cdd:PRK11281    57 EDKLVQQDLEQTLALLDKIDR----QKEETEQLKQQLAQAPAKLRQAQAE-----LEALKDDNDEETRETLSTLS--LRQ 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1175 MQNSLTATQTDLTQTLKALS---------QTQAElqRSGAKLQELQTSSKDMNQELEAELEqacadrdaaarSLEELMSS 1245
Cdd:PRK11281   126 LESRLAQTLDQLQNAQNDLAeynsqlvslQTQPE--RAQAALYANSQRLQQIRNLLKGGKV-----------GGKALRPS 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1246 HKAVLQErEQQALHleekeeqlkqevLRLQEERSSLKKNseqevgqlwTQLESMRTSRQELGELKEQLLARsarvdDIER 1325
Cdd:PRK11281   193 QRVLLQA-EQALLN------------AQNDLQRKSLEGN---------TQLQDLLQKQRDYLTARIQRLEH-----QLQL 245

                          250       260
                   ....*....|....*....|..
gi 1838138447 1326 LKTEFNEQKREIKEQNEAELES 1347
Cdd:PRK11281   246 LQEAINSKRLTLSEKTVQEAQS 267
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 654-892 2.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  654 LLVPAITPSEEEDELVGELKKKKQQdLLLSQQEIKQPAISAEQILELRDDkplQTLQVEAMVGQLETLQSELGLKEVELK 733
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQE-IAELEKELAALKKEEKALLKQLAA---LERRIAALARRIRALEQELAALEAELA 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  734 HLALQLEQLTNQNADHVNDLQEQIDALKAQCEH----LLLHLEEMTTTHKTTAAL------IDEKTTELDRTSKELERTR 803
Cdd:COG4942     87 ELEKEIAELRAELEAQKEELAELLRALYRLGRQpplaLLLSPEDFLDAVRRLQYLkylapaRREQAEELRADLAELAALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  804 AQVVNVQTEVDRLQGELEKSLDSLDTAEQVKSELesqifclkqnLAKLEEAQAQTEQEREERRRKEEEMDDQIKKMEQVL 883
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKL----------LARLEKELAELAAELAELQQEAEELEALIARLEAEA 236


                   ....*....
gi 1838138447  884 EEELEQFES 892
Cdd:COG4942    237 AAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 3569-3800 2.77e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3569 ALSQRKDREKEERREALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLDDTQKELGD-ERQLSAN 3647
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAElEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3648 QKELKLQdKTRLERLLAEAE--SRLAEIHSTLAEAHRKVDEERERYSRQVDELSRRHEADATRDRKFISDMRAQLEQERR 3725
Cdd:COG4942     96 RAELEAQ-KEELAELLRALYrlGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1838138447 3726 QGEELAAVMNKLRAELLQSRSKWEEEDRARRAELQREKEAAIQQRVAVETLKEQKQETCCALEMERARSTQQGVE 3800
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFA 249
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2928-3101 2.79e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 2.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2928 QEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQ--EMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEeri 3005
Cdd:COG4913    617 AELAELEEELAEAEERLEALEAELDALQERREALQRLAEysWDEIDVASAEREIAELEAELERLDASSDDLAALEEQ--- 693

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3006 kIKTLKTVKGELSAERETLRRREGKLQEEIENLRQEATSMRA--------CIQELTVQLNER--EASQEEAQKEVLTHAE 3075
Cdd:COG4913    694 -LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDrleaaedlARLELRALLEERfaAALGDAVERELRENLE 772

                          170       180
                   ....*....|....*....|....*.
gi 1838138447 3076 VTLAKADAALRQREAELARLRAEHQA 3101
Cdd:COG4913    773 ERIDALRARLNRAEEELERAMRAFNR 798
PTZ00121 PTZ00121
MAEBL; Provisional
 3501-3877 2.81e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 2.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3501 DRVDGQVESQLRAELEESQKQLKCAHDTQQEHKNKMQSVRVAVAEGEEALRREQVRvqelQQQLEQERALSQRKDREKEE 3580
Cdd:PTZ00121  1408 DELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAK----KKAEEAKKADEAKKKAEEAK 1483

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3581 RREALHVSSEQQRSEVMALKGLVEQERVACSNLRRE--LQIEQSRSELLEKRLDDTQK--ELGDERQLSANQKELKLQDK 3656
Cdd:PTZ00121  1484 KADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEeaKKADEAKKAEEAKKADEAKKaeEKKKADELKKAEELKKAEEK 1563

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3657 TRLERLLAEAESRLAEIHStlAEAHRKVDEERERYSRQVDELSRRHEADATRDRKfisDMRAQLEQERRQGEELAAVMNK 3736
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMALRK--AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE---EAKIKAEELKKAEEEKKKVEQL 1638

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3737 LRAELLQSRS-----KWEEEDRARRAELQREKEAaiQQRVAVETLKEQKQETCCALEMERARSTQQGVELTELKEKlhli 3811
Cdd:PTZ00121  1639 KKKEAEEKKKaeelkKAEEENKIKAAEEAKKAEE--DKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEA---- 1712

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1838138447 3812 KDKEREREEQWERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQHTLVELEREEKE 3877
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2878-3086 3.72e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2878 KRLTAEREKADKLQSVLTLKEAELDEVKAQ-KEGDAEERKLSEEVNDkvQNQEMSTLRDKNLHLNSLIAEVQKKEQERVT 2956
Cdd:COG4942     34 QEIAELEKELAALKKEEKALLKQLAALERRiAALARRIRALEQELAA--LEAELAELEKEIAELRAELEAQKEELAELLR 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2957 EMDTLKTKE-----------QEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLR 3025
Cdd:COG4942    112 ALYRLGRQPplalllspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALE 191

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1838138447 3026 RREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEVLTHAEVTLAKADAALR 3086
Cdd:COG4942    192 ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2899-3162 3.75e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 3.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2899 AELDEVKAQKEGDAEERKLSEEVNDKVqnqemstLRDKNLHLNSLiaevqKKEQERVTEMDTLKTKEQEMEMeTEVLRET 2978
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLI-------IDEKRQQLERL-----RREREKAERYQALLKEKREYEG-YELLKEK 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2979 sLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLRRREGKLQEEienlrqEATSMRACIQELTVQLNE 3058
Cdd:TIGR02169  233 -EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE------EQLRVKEKIGELEAEIAS 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3059 REASQEEAQKEvlthaevtlakadaaLRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRALLNLE 3138
Cdd:TIGR02169  306 LERSIAEKERE---------------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLR 370

                          250       260
                   ....*....|....*....|....
gi 1838138447 3139 TDNQRLKAQLRALQEDLAVQEEEL 3162
Cdd:TIGR02169  371 AELEEVDKEFAETRDELKDYREKL 394
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2944-3106 3.95e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 3.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2944 IAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVK--GELSAER 3021
Cdd:COG1579     19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKeyEALQKEI 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3022 ETLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEVlthaevtlakaDAALRQREAELARLRAEHQA 3101
Cdd:COG1579     99 ESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL-----------DEELAELEAELEELEAEREE 167


                   ....*
gi 1838138447 3102 LKAEL 3106
Cdd:COG1579    168 LAAKI 172
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1038-1382 4.18e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 4.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1038 RESMEAAHQAELLQHQVQKRSELEAMRlsltnahvsQLEQESALTEAQGSPRDTFAQEIALLKAQHQAELDHIRQQEKLR 1117
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRR---------KLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1118 ELQQqpmndlqqqwetlVAQERAAMEEEQAKDIQALRSQWDKNAESRESNLQmflsemqnsltatqtdltqtlKALSQTQ 1197
Cdd:pfam17380  361 ELER-------------IRQEEIAMEISRMRELERLQMERQQKNERVRQELE---------------------AARKVKI 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1198 AELQRSGAKLQELQTSSKDMNQELEAELEQACADRDAAARSLEELMSSHkavlQEREQQALHLEEKEEQLKQEVLRLQEE 1277
Cdd:pfam17380  407 LEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEE----QERQQQVERLRQQEEERKRKKLELEKE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 1278 RSSLKKNSEQEVGQLWTQLESMRTSRQElGELKEQLLARSARvddiERLKTEFNEQKREIKEQ---NEAELESLRRYFEQ 1354
Cdd:pfam17380  483 KRDRKRAEEQRRKILEKELEERKQAMIE-EERKRKLLEKEME----ERQKAIYEEERRREAEEerrKQQEMEERRRIQEQ 557

                          330       340
                   ....*....|....*....|....*...
gi 1838138447 1355 RLRATEEGHREEiALLQLRLVERALEES 1382
Cdd:pfam17380  558 MRKATEERSRLE-AMEREREMMRQIVES 584
PTZ00121 PTZ00121
MAEBL; Provisional
 5-400 4.89e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 4.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447    5 ERQRKLETGRaKKASEMPRSQSLASYRQKREKGNSAGTSKKTQKRKGQTVSQndgATQGRPVDAALSSANDTELNKKTNH 84
Cdd:PTZ00121  1299 EEKKKADEAK-KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAK---AEAEAAADEAEAAEEKAEAAEKKKE 1374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447   85 EEPQKPEKSKVQPPALEQSPSPVEDIEEEELIA--LTGKEQLKQLQEAVEKRNEIIARLSSNLQEALASR--DQVQLEAQ 160
Cdd:PTZ00121  1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKKKAdeLKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKkaDEAKKKAE 1454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  161 SLAGQIQGLQRQLQQTSVEFLRIKSQSGAEVLNTRQPHGRCSQDADLNHKEAPSGSAAPETISCVEGFSTDTALEKLRVE 240
Cdd:PTZ00121  1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK 1534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  241 LEEERKNSQRIyaELALEMEKHQHVLSLLEKEK-NSREEEQKEKEEQLQDLQMQFSLVQTQCLEMQQYKEEKEKLNREvl 319
Cdd:PTZ00121  1535 KADEAKKAEEK--KKADELKKAEELKKAEEKKKaEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE-- 1610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  320 ELRKRLQEEADAER-RLGEEVASSALRLQRQEEEMLRLKEEHR--EEVEGVRQLLEEREKELKFREEEVLGlKASKNRQN 396
Cdd:PTZ00121  1611 EAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKkaEEENKIKAAEEAKKAEEDKKKAEEAK-KAEEDEKK 1689


                   ....
gi 1838138447  397 KAKA 400
Cdd:PTZ00121  1690 AAEA 1693
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2928-3133 5.03e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 5.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2928 QEMSTLRDKNLHLNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKI 3007
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3008 KTL----------KTVKGELSAER-ETLRRREGKLQEEIENLRQEATSMRACIQELTvQLNEREASQEEAQKEVLTHAEV 3076
Cdd:COG4942    107 AELlralyrlgrqPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELA-ALRAELEAERAELEALLAELEE 185

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1838138447 3077 TLAKADAALRQREAELARLRAEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRA 3133
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 3545-3902 5.17e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.04  E-value: 5.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3545 EGEEALRREQVRVQELQQQLEQERALSQRKDREKEERREALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQ-IEQSR 3623
Cdd:pfam02463  170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQeLLRDE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3624 SELLEKRLDDTQKELGDERQLSANQKELKLQDKTRLERLLAEAESRLAEIHSTLAEAHRKVDEERERYSRQVDElsRRHE 3703
Cdd:pfam02463  250 QEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEK--KKAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3704 ADATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAELLQSRSKWEEEDRARRAELQREKEAAIQQRVAVETLKEQKQET 3783
Cdd:pfam02463  328 KELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEA 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3784 CCALEMERarstQQGVELTELKEKLHLIKDKEREREEQWERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQE 3863
Cdd:pfam02463  408 QLLLELAR----QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 1838138447 3864 LQHTLVELEREEKEMSAQRLRQHNIAASSQHLQSDFQTG 3902
Cdd:pfam02463  484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG 522
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 3510-3750 5.76e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 5.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3510 QLRAELEESQKQLKCAHDTQQEHKNKMQSVRVAVAEGEEALRREQVRvqelQQQLEQERALSQRKDREKEERREALHVSS 3589
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKE----IEQLEQEEEKLKERLEELEEDLSSLEQEI 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3590 EQQRSEVMALKGLVEQERVACSNLRREL----------QIEQSRSEL---------LEKRLDDTQKELGDERQLsanqKE 3650
Cdd:TIGR02169  754 ENVKSELKELEARIEELEEDLHKLEEALndlearlshsRIPEIQAELskleeevsrIEARLREIEQKLNRLTLE----KE 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3651 LKLQDKTRLERLLAEAESRLAEIHSTLAEAH---RKVDEERERYSRQVDELSRRHEaDATRDRKfisDMRAQLEQERRQG 3727
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNgkkEELEEELEELEAALRDLESRLG-DLKKERD---ELEAQLRELERKI 905

                          250       260
                   ....*....|....*....|...
gi 1838138447 3728 EELAAVMNKLRAELLQSRSKWEE 3750
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEA 928
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 2943-3159 5.77e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 5.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2943 LIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERE 3022
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3023 TLRRREGKLQEEIENLRQEATSMRACIQELTVQLNEREASQEEAQKEV------LTHAEVTLAKADAALRQREAELARLR 3096
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAkkagaqRKEEEAERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1838138447 3097 AEHQALKAELTEVKQGLSTSTERAEKLHEEGQTKDRAllnlETDNQRLKAQLRALQEDLAVQE 3159
Cdd:pfam07888  192 KEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRK----EAENEALLEELRSLQERLNASE 250
mukB PRK04863
chromosome partition protein MukB;
3646-3952 6.44e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 6.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3646 ANQKELKLQDKTRLERLLAEAESRLAEIHSTLAEAHRKVDEERERYSrqvdELSRRHEADATRDRKFISDMRAQlEQERR 3725
Cdd:PRK04863   278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAES----DLEQDYQAASDHLNLVQTALRQQ-EKIER 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3726 QGEELAAVMNKLRAEL----LQSRSKWEEEDRARRAELQREKEA----------------AIQQRVAVETLKEQKQetCC 3785
Cdd:PRK04863   353 YQADLEELEERLEEQNevveEADEQQEENEARAEAAEEEVDELKsqladyqqaldvqqtrAIQYQQAVQALERAKQ--LC 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3786 AL------------EMERARSTQQGVELTELKEKLHLIKDKEREREEQWERERRKGrqEQMERERRQERTNDKLCELEML 3853
Cdd:PRK04863   431 GLpdltadnaedwlEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIA--GEVSRSEAWDVARELLRRLREQ 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3854 RQQDQQRmQELQHTLVELEreekemsaQRLRQHNIAassQHLQSDFQtgsaQHNQQMPSSQNLLERmmkENSELTECVTS 3933
Cdd:PRK04863   509 RHLAEQL-QQLRMRLSELE--------QRLRQQQRA---ERLLAEFC----KRLGKNLDDEDELEQ---LQEELEARLES 569

                          330
                   ....*....|....*....
gi 1838138447 3934 LSQEKATLKHRLTFLEREL 3952
Cdd:PRK04863   570 LSESVSEARERRMALRQQL 588
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 2247-2601 6.78e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.79  E-value: 6.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2247 EDSAQLLVQHKILLEQLDQEAKLKSELQLEYHKTEGLLEGYVAEKALLEESLQQKEVQEERLVEELEDLKVKLHQMQ--- 2323
Cdd:pfam05483  408 EELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKlkn 487

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2324 -GLTAELDGLRLKHQELSEEHS---LLLRQKEHLSAGLGEREKALLAETERLTQDRLDLQRQAEKDHKSLSLRLRALERD 2399
Cdd:pfam05483  488 iELTAHCDKLLLENKELTQEASdmtLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCK 567

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2400 LEEKETQDLETEQH---HKTHNEDLNQRVQALEKQLKHDRQFIEEQAVEREHERDEFQQEIRSLEAQLRQTASVD----N 2472
Cdd:pfam05483  568 LDKSEENARSIEYEvlkKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLElelaS 647

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2473 KGHRFQDLvlqVESLQAIIKDKTEDHDSLIAANQQAQRDLAEC---NEEIDKLAGRIRELEQALLNDAEGK--RSISQLE 2547
Cdd:pfam05483  648 AKQKFEEI---IDNYQKEIEDKKISEEKLLEEVEKAKAIADEAvklQKEIDKRCQHKIAEMVALMEKHKHQydKIIEERD 724

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1838138447 2548 QELHRSKLREQELSQDKQALEQQQLSNRLQISALQSKVDETRHCYHDNQREPTQ 2601
Cdd:pfam05483  725 SELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKE 778
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
3511-3882 6.92e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 42.72  E-value: 6.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3511 LRAELEESQKQLKCAHDTQQEHKNKMQSVRVAVAEGEEALRReqvRVQELQQQLEQERALSQRKDrEKEERREALHVSSE 3590
Cdd:PRK02224   256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDD---LLAEAGLDDADAEAVEARRE-ELEDRDEELRDRLE 331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3591 QQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLDDTQKELGDER-QLSANQKELKLQDKT---------RLE 3660
Cdd:PRK02224   332 ECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRReEIEELEEEIEELRERfgdapvdlgNAE 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3661 RLLAEAESRLAEIHSTLAEAHRKVDEERERY---------------------SRQVDELSRRHE--ADATRDRKFISDMR 3717
Cdd:PRK02224   412 DFLEELREERDELREREAELEATLRTARERVeeaealleagkcpecgqpvegSPHVETIEEDRErvEELEAELEDLEEEV 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3718 AQLEQERRQGEELAAVMNKL----------------RAELLQSRSKWEEEDRARRAELQREKEAAIQQRVAVETLKEQKQ 3781
Cdd:PRK02224   492 EEVEERLERAEDLVEAEDRIerleerredleeliaeRRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3782 ETCCALEMERARSTQQGVELTELKEKLHLIKDKEREREEQWERERRKGRQEQMERER---RQERTNDKLCELEMLR-QQD 3857
Cdd:PRK02224   572 EEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERlaeKRERKRELEAEFDEARiEEA 651

                          410       420
                   ....*....|....*....|....*
gi 1838138447 3858 QQRMQELQHTLVELEREEKEMSAQR 3882
Cdd:PRK02224   652 REDKERAEEYLEQVEEKLDELREER 676
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3742-3962 7.67e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 7.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3742 LQSRSKWEEEDRARRAELQREKEAAIQQRVAVETLKEQKQETCCALEMERARSTQQGVELTELKEKLHLIKDKEREREEQ 3821
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3822 WERERRKGRQEQMERERRQERTNDKLCELEMLRQQDQQRMQELQHTLVELEREEKEMSAQrLRQHNIAASSQhlqsdfQT 3901
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE-LTLLNEEAANL------RE 824

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1838138447 3902 GSAQHNQQMPSSQNLLERMMKENSELTECVTSLSQEKATLKHRLTFLERELRLTENELAKV 3962
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 3474-3771 8.17e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.52  E-value: 8.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3474 VALRELLCRMAQRPTQTDHRVEGDW-------HGDRVD----GQVESQLRAELEESQKQLKCAHDTQQEHKNKMQSVRVA 3542
Cdd:pfam12128  554 VISPELLHRTDLDPEVWDGSVGGELnlygvklDLKRIDvpewAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGE 633

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3543 VaegEEALRREQVRVQELQQQLEQERALSQRKDREKEERREALhvsSEQQRSEVMALKGLVEQERVacsnLRRELQ--IE 3620
Cdd:pfam12128  634 L---EKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKAL---AERKDSANERLNSLEAQLKQ----LDKKHQawLE 703

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3621 QSRSELLEKRLDDTQKELGDERQLSANQKELKLQDKTRLERLLAEAESRLAEIHSTLAEahRKVDEER-ERYSRQVDELS 3699
Cdd:pfam12128  704 EQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLAS--LGVDPDViAKLKREIRTLE 781

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1838138447 3700 RRHEADATRDRKFISDMRAQLEQERRQGEELAAVMNKLRAELLQSR---SKWEEEDRARRAELQREKEAAIQQRV 3771
Cdd:pfam12128  782 RKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQqqlARLIADTKLRRAKLEMERKASEKQQV 856
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 3568-3878 8.34e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 8.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3568 RALSQRKDREKE----ERREALHVSSEQQRSEVMALKGLVEQERVACSNLRRELQIEQSRSELLEKRLDDTQKELGD-ER 3642
Cdd:TIGR02169  665 GILFSRSEPAELqrlrERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEElEE 744

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3643 QLSANQKEL--KLQDKTRLERLLAEAESRLAEIHSTLAEAHRKVDEER----ERYSRQVDELSRRHEA----------DA 3706
Cdd:TIGR02169  745 DLSSLEQEIenVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRipeiQAELSKLEEEVSRIEArlreieqklnRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3707 TRDRKFISDMRAQLEQERR----QGEELAAVMNKLRAELLQSRSKWEE------EDRARRAELQREKEAAIQQrvaVETL 3776
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIdlkeQIKSIEKEIENLNGKKEELEEELEEleaalrDLESRLGDLKKERDELEAQ---LREL 901

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3777 KEQKQETCCALEMERARSTQQGVELTELKEKLHLIkDKEREREEQWERERRKGRQEQMERERRQERTNDkLCELEMLRQQ 3856
Cdd:TIGR02169  902 ERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI-EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA-LEPVNMLAIQ 979

                          330       340
                   ....*....|....*....|....*.
gi 1838138447 3857 D----QQRMQELQHTLVELEREEKEM 3878
Cdd:TIGR02169  980 EyeevLKRLDELKEKRAKLEEERKAI 1005
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
2940-3126 8.43e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 41.43  E-value: 8.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2940 LNSLIAEVQKKEQERVTEMDTLKTKEQEMEMETEVLRETSLTLERQVQEMRAELVDMEELVDEERIKIKTLKTVKGELSA 3019
Cdd:COG1340      6 LSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3020 ERETLRRREGKLQEEIENLRQEATSmracIQELTVQLNEREASQE------EAQKEVLTHAEVTLAKADAALRQREA--E 3091
Cdd:COG1340     86 KLNELREELDELRKELAELNKAGGS----IDKLRKEIERLEWRQQtevlspEEEKELVEKIKELEKELEKAKKALEKneK 161

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1838138447 3092 LARLRAEHQALKAELTEVKQGLSTSTERAEKLHEE 3126
Cdd:COG1340    162 LKELRAELKELRKEAEEIHKKIKELAEEAQELHEE 196
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
3615-3739 9.12e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.15  E-value: 9.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3615 RELQIEQSRSELLEKRLDDTQKE-----LGDERQLSANQKELKlqdktRLERLLAEAESRLAEIHSTLAEAhrkvDEERE 3689
Cdd:COG2433    374 RGLSIEEALEELIEKELPEEEPEaerekEHEERELTEEEEEIR-----RLEEQVERLEAEVEELEAELEEK----DERIE 444

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1838138447 3690 RYSRQVDELSRRHEADATRDRKF------ISDMRAQLEQERRQGEELAAVMNKLRA 3739
Cdd:COG2433    445 RLERELSEARSEERREIRKDREIsrldreIERLERELEEERERIEELKRKLERLKE 500
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 2847-3155 9.72e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.12  E-value: 9.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2847 QLEAAAAEKEGLERLLLTQEEEYRGHGEEFGKR--LTAEREKADKLQSVLTLKEAE---LDEVKAQKEGDAEERKLSEEV 2921
Cdd:pfam10174  186 RIAEAEMQLGHLEVLLDQKEKENIHLREELHRRnqLQPDPAKTKALQTVIEMKDTKissLERNIRDLEDEVQMLKTNGLL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2922 NDKVQNQEMSTLRDKNLH-------LNSLIAEVQKKEQERV---TEMDTLKTKEQEMEMETEVLRET-------SLTLER 2984
Cdd:pfam10174  266 HTEDREEEIKQMEVYKSHskfmknkIDQLKQELSKKESELLalqTKLETLTNQNSDCKQHIEVLKESltakeqrAAILQT 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 2985 QVQEMRAELVDMEELVDEERIKIKTLKTVKGELSAERETLR-------RREGKLQEEIENLRQEA-------TSMRACIQ 3050
Cdd:pfam10174  346 EVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKdmldvkeRKINVLQKKIENLQEQLrdkdkqlAGLKERVK 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447 3051 ELTVQLNERE---ASQEEAQKEVLTHAEVTLAKADAALRQREAELARLRAEHQ-------ALKAELTEVKQGLSTSTERA 3120
Cdd:pfam10174  426 SLQTDSSNTDtalTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKdlkekvsALQPELTEKESSLIDLKEHA 505

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 1838138447 3121 EKLHEEGQTKDRALLNLETDNQRLKAQLRALQEDL 3155
Cdd:pfam10174  506 SSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQL 540
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 578-857 9.86e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 9.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  578 EELEEARSRWGQ---VTEELRQALWELEEEKekkrlaeeemnLKAHEQDNLKSKLsalmeeREKEKAVLLTGKEAAETSL 654
Cdd:TIGR02169  177 EELEEVEENIERldlIIDEKRQQLERLRRER-----------EKAERYQALLKEK------REYEGYELLKEKEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  655 --LVPAITPSEEEDELVGELKKKKQQDLLLSQQEIKQpaiSAEQILELRDDKPLQ-TLQVEAMVGQLETLQSELGLKEVE 731
Cdd:TIGR02169  240 eaIERQLASLEEELEKLTEEISELEKRLEEIEQLLEE---LNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1838138447  732 LKHLALQLEQLTNQnadhVNDLQEQIDALKAQCEHLLLHLEEMTTTHKTTAALIDEKTTELDRTSKELERTRAQVVNVQT 811
Cdd:TIGR02169  317 LEDAEERLAKLEAE----IDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1838138447  812 EVDRLQGELEKSLDSLDTAEQVKSELESQIFCLKQNLAKLEEAQAQ 857
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE 438
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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