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Conserved domains on  [gi|1953347519|ref|XP_038293582|]
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ZW10 interactor isoform X5 [Canis lupus familiaris]

Protein Classification

ZW10 interactor( domain architecture ID 710300)

ZW10 interactor (ZWINT) is involved in kinetochore formation and spindle checkpoint activity. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochore.

Gene Ontology:  GO:0007093|GO:0000776
PubMed:  21775627|15824131

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Zwint super family cl25779
ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are ...
 31-275 7.09e-111

ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are typically between 127 and 281 amino acids in length.


The actual alignment was detected with superfamily member pfam15556:

Pssm-ID: 464766 [Multi-domain]  Cd Length: 252  Bit Score: 320.77  E-value: 7.09e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  31 QEEVELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEGIVQGLDPLASEDTSRQKALAVKEQWKELKATYQEHVE 110
Cdd:pfam15556   1 QEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEDTAQGLDPLASEDTSRQKAIAAKEQWKELKATYQEHVE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 111 AITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQEKRLQHLAEASAEVRQRQRGAQQELERL 190
Cdd:pfam15556  81 AITSALTQALPKMEEAQRKRAQLQEALEQLQAKKQMAMEKLRTAQKQWQLQQEKHLQHLAEVSAEVRERQTGTQQELERL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 191 RQELGALQQQAGQKRDRLQRHQTFLRLLHILQGEPLLPGAETERPQELGIPEAK------PREQNTGDAVGKDRSVPSQA 264
Cdd:pfam15556 161 YQELGTLKQQAGQERDKLQRHQTFLQLLYTLQGKLLFPEAEAELPQKLDLPEDKsqqltqPQEQNTGDTMGRDRAVSSKA 240

                         250
                  ....*....|.
gi 1953347519 265 DGLQPARGTSS 275
Cdd:pfam15556 241 DGPQPAGDASL 251
 
Name Accession Description Interval E-value
Zwint pfam15556
ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are ...
 31-275 7.09e-111

ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are typically between 127 and 281 amino acids in length.


Pssm-ID: 464766 [Multi-domain]  Cd Length: 252  Bit Score: 320.77  E-value: 7.09e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  31 QEEVELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEGIVQGLDPLASEDTSRQKALAVKEQWKELKATYQEHVE 110
Cdd:pfam15556   1 QEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEDTAQGLDPLASEDTSRQKAIAAKEQWKELKATYQEHVE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 111 AITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQEKRLQHLAEASAEVRQRQRGAQQELERL 190
Cdd:pfam15556  81 AITSALTQALPKMEEAQRKRAQLQEALEQLQAKKQMAMEKLRTAQKQWQLQQEKHLQHLAEVSAEVRERQTGTQQELERL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 191 RQELGALQQQAGQKRDRLQRHQTFLRLLHILQGEPLLPGAETERPQELGIPEAK------PREQNTGDAVGKDRSVPSQA 264
Cdd:pfam15556 161 YQELGTLKQQAGQERDKLQRHQTFLQLLYTLQGKLLFPEAEAELPQKLDLPEDKsqqltqPQEQNTGDTMGRDRAVSSKA 240

                         250
                  ....*....|.
gi 1953347519 265 DGLQPARGTSS 275
Cdd:pfam15556 241 DGPQPAGDASL 251
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
99-239 6.04e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 6.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   99 KELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQ-EKRLQHLAEAS---- 173
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAElEAELERLDASSddla 688

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953347519  174 ------AEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQRHQTFLRLLHILQGEPLLPGAETERPQELG 239
Cdd:COG4913    689 aleeqlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG 760
mukB PRK04863
chromosome partition protein MukB;
99-201 3.31e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 3.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   99 KELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQaKKQVAMERARTAQKQWQLQQEKRLQHLAEASAEVRQ 178
Cdd:PRK04863   501 LLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFC-KRLGKNLDDEDELEQLQEELEARLESLSESVSEARE 579

                           90       100
                   ....*....|....*....|...
gi 1953347519  179 RQRGAQQELERLRQELGALQQQA 201
Cdd:PRK04863   580 RRMALRQQLEQLQARIQRLAARA 602
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 89-209 7.81e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.81  E-value: 7.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   89 QKALAVKEQWKELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQwqlQQEKRLQH 168
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK---LEEAELKE 437

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1953347519  169 LAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQ 209
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478
 
Name Accession Description Interval E-value
Zwint pfam15556
ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are ...
 31-275 7.09e-111

ZW10 interactor; This family of proteins is found in eukaryotes. Proteins in this family are typically between 127 and 281 amino acids in length.


Pssm-ID: 464766 [Multi-domain]  Cd Length: 252  Bit Score: 320.77  E-value: 7.09e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  31 QEEVELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEGIVQGLDPLASEDTSRQKALAVKEQWKELKATYQEHVE 110
Cdd:pfam15556   1 QEEAELPAQILAEFVMDSRKKDKLLCSQLQVVDFLQNFLAQEDTAQGLDPLASEDTSRQKAIAAKEQWKELKATYQEHVE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 111 AITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQEKRLQHLAEASAEVRQRQRGAQQELERL 190
Cdd:pfam15556  81 AITSALTQALPKMEEAQRKRAQLQEALEQLQAKKQMAMEKLRTAQKQWQLQQEKHLQHLAEVSAEVRERQTGTQQELERL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 191 RQELGALQQQAGQKRDRLQRHQTFLRLLHILQGEPLLPGAETERPQELGIPEAK------PREQNTGDAVGKDRSVPSQA 264
Cdd:pfam15556 161 YQELGTLKQQAGQERDKLQRHQTFLQLLYTLQGKLLFPEAEAELPQKLDLPEDKsqqltqPQEQNTGDTMGRDRAVSSKA 240

                         250
                  ....*....|.
gi 1953347519 265 DGLQPARGTSS 275
Cdd:pfam15556 241 DGPQPAGDASL 251
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
99-239 6.04e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 6.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   99 KELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQ-EKRLQHLAEAS---- 173
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAElEAELERLDASSddla 688

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953347519  174 ------AEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQRHQTFLRLLHILQGEPLLPGAETERPQELG 239
Cdd:COG4913    689 aleeqlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG 760
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 81-210 7.03e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 7.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  81 LASEDTSRQKALAVKEQWKELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQwQL 160
Cdd:COG1196   241 LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER-LE 319

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1953347519 161 QQEKRLQHLAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQR 210
Cdd:COG1196   320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 93-212 1.12e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 1.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  93 AVKEQWKELKATYQEH---VEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQEK----- 164
Cdd:COG1196   236 ELEAELEELEAELEELeaeLEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERrrele 315

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1953347519 165 -RLQHLAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQRHQ 212
Cdd:COG1196   316 eRLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 81-210 1.27e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.47  E-value: 1.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  81 LASEDTSRQKALAVKEQWKELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQL 160
Cdd:COG1196   304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1953347519 161 QQEKRLQHLAEAsAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQR 210
Cdd:COG1196   384 LAEELLEALRAA-AELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
81-217 1.40e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 1.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  81 LASEDTSRQKALAVKEQWKELKATYQEHVEaitgaLTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQL 160
Cdd:COG4717   114 LREELEKLEKLLQLLPLYQELEALEAELAE-----LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSL 188

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1953347519 161 QQEKRLQHLAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQRHQTFLRL 217
Cdd:COG4717   189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERL 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
99-220 1.44e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   99 KELKATYQEHVEAITGALTQ----ALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQEKRLQhlaeasA 174
Cdd:COG4913    255 EPIRELAERYAAARERLAELeylrAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDE------L 328

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1953347519  175 EVRQRQRGAQQeLERLRQELGALQQQAGQKRDRLQRHQTFLRLLHI 220
Cdd:COG4913    329 EAQIRGNGGDR-LEQLEREIERLERELEERERRRARLEALLAALGL 373
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 89-213 1.51e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.08  E-value: 1.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  89 QKALAVKEQWKELKATYQ-EHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQEKRLQ 167
Cdd:COG1196   213 ERYRELKEELKELEAELLlLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1953347519 168 HLAEASAEVRQRQRgAQQELERLRQELGALQQQAGQKRDRLQRHQT 213
Cdd:COG1196   293 LLAELARLEQDIAR-LEERRRELEERLEELEEELAELEEELEELEE 337
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 82-218 2.54e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 2.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  82 ASEDTSRQKALAVKEQWKELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQvAMERARTAQKQWQLQ 161
Cdd:COG1196   351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE-RLERLEEELEELEEA 429

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1953347519 162 QEKRLQHLAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQRHQTFLRLL 218
Cdd:COG1196   430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 82-224 2.99e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 2.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519  82 ASEDTSRQKALAVKEQWKELKATYQEH---VEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKK---QVAMERARTAQ 155
Cdd:COG1196   267 AELEELRLELEELELELEEAQAEEYELlaeLARLEQDIARLEERRRELEERLEELEEELAELEEELeelEEELEELEEEL 346

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953347519 156 KQWQLQQEKRLQHLAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQRHQTFLRLLHILQGE 224
Cdd:COG1196   347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415
mukB PRK04863
chromosome partition protein MukB;
99-201 3.31e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 3.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   99 KELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQaKKQVAMERARTAQKQWQLQQEKRLQHLAEASAEVRQ 178
Cdd:PRK04863   501 LLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFC-KRLGKNLDDEDELEQLQEELEARLESLSESVSEARE 579

                           90       100
                   ....*....|....*....|...
gi 1953347519  179 RQRGAQQELERLRQELGALQQQA 201
Cdd:PRK04863   580 RRMALRQQLEQLQARIQRLAARA 602
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
78-212 4.97e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 4.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   78 LDPLASEDTSRQKALAVKEQWKELKATYQehVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQ 157
Cdd:COG4913    254 LEPIRELAERYAAARERLAELEYLRAALR--LWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQ 331

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1953347519  158 WQLQQEKRLQHLAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQRHQ 212
Cdd:COG4913    332 IRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALR 386
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
82-200 5.53e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 5.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   82 ASEDTSRQKALAVKEQWKELKATYQEH----VEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQ 157
Cdd:COG4913    309 AELERLEARLDALREELDELEAQIRGNggdrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE 388

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1953347519  158 WQLQQEKRLQHLAEAS---AEVRQRQRGAQQELERLRQELGALQQQ 200
Cdd:COG4913    389 AAALLEALEEELEALEealAEAEAALRDLRRELRELEAEIASLERR 434
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 112-210 6.30e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 6.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 112 ITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQlQQEKRLQHLAEASAEVRQRQRGAQQELERLR 191
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQELAALEAELAELE 89

                          90
                  ....*....|....*....
gi 1953347519 192 QELGALQQQAGQKRDRLQR 210
Cdd:COG4942    90 KEIAELRAELEAQKEELAE 108
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 89-209 7.81e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.81  E-value: 7.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   89 QKALAVKEQWKELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQwqlQQEKRLQH 168
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK---LEEAELKE 437

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1953347519  169 LAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQ 209
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 79-196 1.16e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 40.32  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   79 DPLASEDTSRQKALAVKEQWKEL---KATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQ 155
Cdd:PRK11448   139 DPENLLHALQQEVLTLKQQLELQareKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQKR 218

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1953347519  156 KQWQLQQEKRLQhLAEasAEVRQ------RQRGAQQELERLRQELGA 196
Cdd:PRK11448   219 KEITDQAAKRLE-LSE--EETRIlidqqlRKAGWEADSKTLRFSKGA 262
COG5283 COG5283
Phage-related tail protein [Mobilome: prophages, transposons];
109-210 1.43e-03

Phage-related tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444094 [Multi-domain]  Cd Length: 747  Bit Score: 40.22  E-value: 1.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 109 VEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQEKRLQHLAEASAEVRQ---RQRGAQQ 185
Cdd:COG5283     5 LGAVDKPFKSALESAKQRVAALAQALKALEAPTRALARALERAKQAAARLQTKYNKLRQSLQRLRQALDQagiDTRQLSA 84

                          90       100
                  ....*....|....*....|....*
gi 1953347519 186 ELERLRQELGALQQQAGQKRDRLQR 210
Cdd:COG5283    85 AQRRLRSSLEQTNRQLERQQQRLAR 109
PRK14507 PRK14507
malto-oligosyltrehalose synthase;
189-246 1.75e-03

malto-oligosyltrehalose synthase;


Pssm-ID: 237737 [Multi-domain]  Cd Length: 1693  Bit Score: 40.09  E-value: 1.75e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1953347519  189 RLRQELGALQQQAGQKRDRLQRHQTFLRLLHILQGEPLLPGAETerPQELGIPEAKPR 246
Cdd:PRK14507   595 DLRQSLGLYPDAERAEAQRTERVAERRRLLEALAAEGLLPSGEP--PDAAPFPELTAE 650
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 89-201 1.93e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 39.55  E-value: 1.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   89 QKALAVKEQWKELKATYQEhVEAITGALTQAlakteeaqSKRVQLQEALEQLQAKKQVAMERARTAQKQ---WQLQQEKR 165
Cdd:COG3096    495 QTARELLRRYRSQQALAQR-LQQLRAQLAEL--------EQRLRQQQNAERLLEEFCQRIGQQLDAAEEleeLLAELEAQ 565

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1953347519  166 LQHLAEASAEVRQRQRGAQQELERLRQELGALQQQA 201
Cdd:COG3096    566 LEELEEQAAEAVEQRSELRQQLEQLRARIKELAARA 601
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 82-210 1.95e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 39.67  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   82 ASEDTSRQKALAVKEQWKELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQA---KKQVAMERARTAQKQW 158
Cdd:TIGR02169  269 EIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAeidKLLAEIEELEREIEEE 348

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953347519  159 QLQQEK-----------------RLQHLAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQR 210
Cdd:TIGR02169  349 RKRRDKlteeyaelkeeledlraELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQR 417
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 78-209 2.68e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 2.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   78 LDPLASEDTSRQKALAVKEQWKELKAT--------YQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAME 149
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAELRELELAllvlrleeLREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE 281

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953347519  150 RARTAQKQWQLQQ------EKRLQHLAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQ 209
Cdd:TIGR02168  282 EIEELQKELYALAneisrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 95-210 3.37e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 38.88  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   95 KEQWKELKATYQEHVEAITGALTQALAKTEEAQSKRVQLQEALEQLQAKKQVAMERARTAQKQWQLQQEKR------LQH 168
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLanlerqLEE 320

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 1953347519  169 LAEASAEVRQRQRGAQQELERLRQELGALQQQAGQKRDRLQR 210
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEE 362
PRK09039 PRK09039
peptidoglycan -binding protein;
115-212 4.69e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 38.02  E-value: 4.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 115 ALTQALAkTEEAQSKrvQLQEALEQLQAKKQVA-MERARTAQKQWQLQQ-----EKRLQHLAEASAEVRQRQRGAQQELE 188
Cdd:PRK09039   64 ELADLLS-LERQGNQ--DLQDSVANLRASLSAAeAERSRLQALLAELAGagaaaEGRAGELAQELDSEKQVSARALAQVE 140

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1953347519 189 RLRQELGALQQQ---------AGQKRDRLQRHQ 212
Cdd:PRK09039  141 LLNQQIAALRRQlaaleaaldASEKRDRESQAK 173
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 115-215 7.40e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 37.44  E-value: 7.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519 115 ALTQALAKTEEAQSKRVQLQEALEQLQAKKQvamERARTAQKQWQLQQEkrLQHLAEASAEVRQRQRGAQQELERLRQEL 194
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEK---ELAALKKEEKALLKQ--LAALERRIAALARRIRALEQELAALEAEL 85

                          90       100
                  ....*....|....*....|.
gi 1953347519 195 GALQQQAGQKRDRLQRHQTFL 215
Cdd:COG4942    86 AELEKEIAELRAELEAQKEEL 106
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 85-222 8.95e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 37.73  E-value: 8.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953347519   85 DTSRQKALAVKEQWKELKATYQEHVEAITGALTQALAKTEEA-----QSKRVQLQ-EALEQLQAKKQVAMERARTAQKQW 158
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLedleeQIEELSEDiESLAAEIEELEELIEELESELEAL 878

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953347519  159 QLQQEKRLQHLAEASAE---VRQRQRGAQQELERLRQELGALQQQAGQKRDRLQRHQtfLRLLHILQ 222
Cdd:TIGR02168  879 LNERASLEEALALLRSEleeLSEELRELESKRSELRRELEELREKLAQLELRLEGLE--VRIDNLQE 943
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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