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Conserved domains on  [gi|2020852016|ref|XP_040321064|]
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protein HIRA isoform X3 [Puma yagouaroundi]

Protein Classification

HIRA family protein( domain architecture ID 10078067)

HIRA family protein similar to Drosophila melanogaster Protein HIRA homolog required for the periodic repression of histone gene transcription during the cell cycle

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Hira pfam07569
TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are ...
 813-995 1.08e-57

TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are implicated in the assembly of repressive chromatin. These proteins also contain pfam00400.


:

Pssm-ID: 462211  Cd Length: 221  Bit Score: 198.23  E-value: 1.08e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  813 LHCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSILAGS---------DMTVSQILLTQHGIPVMNLSDGKAYCFNPS 883
Cdd:pfam07569   17 LECSGSYLLAVTSVGLLYVWDIKKQKALLPPVSLAPLLDSSsrysdkltrAPTITSASLTSNGVPIVTLSNGDGYLYDKS 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  884 LSTWNLVSDKQDSLA-QCADFRSSLPPQDAMLCSGPLAIVQ----------GRASTSGRQAARLFSVPHVVQQET--TLA 950
Cdd:pfam07569   97 LETWLRISDSWWALGsQYWDSTGSSRSSSQSSAAGILSFLErktneellrkGRGRLLQRLAKTLLMKEGFENFETvvTLA 176

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2020852016  951 YLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDL 995
Cdd:pfam07569  177 HLENRLAAALLLGSPDEYRHWLLMYAKRLAEEGLKGRLRELCKEL 221
WD40 COG2319
WD40 repeat [General function prediction only];
8-385 7.06e-42

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 158.92  E-value: 7.06e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016    8 AALPAPLLRPRRAASLRAVAARPGQLPRVGGapergGPGKPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMSPvlqedde 87
Cdd:COG2319     87 SPDGRLLASASADGTVRLWDLATGLLLRTLT-----GHTGAVRSVAFSPDGKTLASGS---ADGTVRLWDLAT------- 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   88 kdeniPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWkratyigpstvfgssgklaNVEQWRCVSILRSHSGDV 167
Cdd:COG2319    152 -----GKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLW-------------------DLATGKLLRTLTGHTGAV 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  168 MDVAWSPHDAWLASCSVDNTVVIWNaVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITk 247
Cdd:COG2319    208 RSVAFSPDGKLLASGSADGTVRLWD-LATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLT- 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  248 pfdecGGTTHVLRLSWSPDGHYLVSAhamnNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSSAkps 327
Cdd:COG2319    286 -----GHSGGVNSVAFSPDGKLLASG----SDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP--------DGKTL--- 345

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2020852016  328 cpycccAVGSKDRSLSVWLTCLKRPLVVIHElFDKSIMDISWTLNGLGILVCSMDGSV 385
Cdd:COG2319    346 ------ASGSDDGTVRLWDLATGELLRTLTG-HTGAVTSVAFSPDGRTLASGSADGTV 396
Treacle super family cl25490
Treacher Collins syndrome protein Treacle;
531-750 4.28e-05

Treacher Collins syndrome protein Treacle;


The actual alignment was detected with superfamily member pfam03546:

Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 47.37  E-value: 4.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  531 NPQLLPLDSSTPNSFGASKPSTEPVATAGARP---------AGDTASKDSVNATSTPAASS---PSVLTTPSKIEPMKAF 598
Cdd:pfam03546  127 NSQVRPASTVGKGPSGKGANPAPPGKAGSAAPlvqvgkkeeDSESSSEESDSEGEAPPAATqakPSGKILQVRPASGPAK 206

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  599 DSRFTERSKATPGApaltsvTPTTVERLKEQNlvkdlrprDLLESSSDSDEKVPVAKPSSLSKRKLELEvETVEKKKKGR 678
Cdd:pfam03546  207 GAAPAPPQKAGPVA------TQVKAERSKEDS--------ESSEESSDSEEEAPAAATPAQAKPALKTP-QTKASPRKGT 271

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2020852016  679 P--RKESRLMPVSLSVQSPAALTTEKDTVCLSVPAPAlklpmPGPQRAFTLQVSSDPSMYIEVENEVTAVGGVK 750
Cdd:pfam03546  272 PitPTSAKVPPVRVGTPAPWKAGTVTSPACASSPAVA-----RGAQRPEEDSSSSEESESEEETAPAAAVGQAK 340
 
Name Accession Description Interval E-value
Hira pfam07569
TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are ...
 813-995 1.08e-57

TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are implicated in the assembly of repressive chromatin. These proteins also contain pfam00400.


Pssm-ID: 462211  Cd Length: 221  Bit Score: 198.23  E-value: 1.08e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  813 LHCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSILAGS---------DMTVSQILLTQHGIPVMNLSDGKAYCFNPS 883
Cdd:pfam07569   17 LECSGSYLLAVTSVGLLYVWDIKKQKALLPPVSLAPLLDSSsrysdkltrAPTITSASLTSNGVPIVTLSNGDGYLYDKS 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  884 LSTWNLVSDKQDSLA-QCADFRSSLPPQDAMLCSGPLAIVQ----------GRASTSGRQAARLFSVPHVVQQET--TLA 950
Cdd:pfam07569   97 LETWLRISDSWWALGsQYWDSTGSSRSSSQSSAAGILSFLErktneellrkGRGRLLQRLAKTLLMKEGFENFETvvTLA 176

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2020852016  951 YLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDL 995
Cdd:pfam07569  177 HLENRLAAALLLGSPDEYRHWLLMYAKRLAEEGLKGRLRELCKEL 221
WD40 COG2319
WD40 repeat [General function prediction only];
8-385 7.06e-42

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 158.92  E-value: 7.06e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016    8 AALPAPLLRPRRAASLRAVAARPGQLPRVGGapergGPGKPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMSPvlqedde 87
Cdd:COG2319     87 SPDGRLLASASADGTVRLWDLATGLLLRTLT-----GHTGAVRSVAFSPDGKTLASGS---ADGTVRLWDLAT------- 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   88 kdeniPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWkratyigpstvfgssgklaNVEQWRCVSILRSHSGDV 167
Cdd:COG2319    152 -----GKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLW-------------------DLATGKLLRTLTGHTGAV 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  168 MDVAWSPHDAWLASCSVDNTVVIWNaVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITk 247
Cdd:COG2319    208 RSVAFSPDGKLLASGSADGTVRLWD-LATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLT- 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  248 pfdecGGTTHVLRLSWSPDGHYLVSAhamnNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSSAkps 327
Cdd:COG2319    286 -----GHSGGVNSVAFSPDGKLLASG----SDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP--------DGKTL--- 345

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2020852016  328 cpycccAVGSKDRSLSVWLTCLKRPLVVIHElFDKSIMDISWTLNGLGILVCSMDGSV 385
Cdd:COG2319    346 ------ASGSDDGTVRLWDLATGELLRTLTG-HTGAVTSVAFSPDGRTLASGSADGTV 396
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 44-385 7.08e-42

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 155.19  E-value: 7.08e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   44 GPGKPIFSVDIHPDGTKFATGGQgqdSGKVVIWNMSPVLQEDDEKdenipkmlcqmdNHLACVNCVRWSNSGMYLASGGD 123
Cdd:cd00200      7 GHTGGVTCVAFSPDGKLLATGSG---DGTIKVWDLETGELLRTLK------------GHTGPVRDVAASADGTYLASGSS 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  124 DKLIMVWkratyigpstvfgssgklaNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFpEILATL 203
Cdd:cd00200     72 DKTIRLW-------------------DLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETG-KCLTTL 131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  204 RGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSItkpfdecggTTH---VLRLSWSPDGHYLVSAhAMNNsg 280
Cdd:cd00200    132 RGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATL---------TGHtgeVNSVAFSPDGEKLLSS-SSDG-- 199

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  281 pTAQIIEREGWKTNMDFVGHRKAVTVVKFNP--KIFkkkqkngssakpscpycccAVGSKDRSLSVWLTCLKRPLVVI-- 356
Cdd:cd00200    200 -TIKLWDLSTGKCLGTLRGHENGVNSVAFSPdgYLL-------------------ASGSEDGTIRVWDLRTGECVQTLsg 259

                          330       340
                   ....*....|....*....|....*....
gi 2020852016  357 HElfdKSIMDISWTLNGLGILVCSMDGSV 385
Cdd:cd00200    260 HT---NSVTSLAWSPDGKRLASGSADGTI 285
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 153-192 1.42e-09

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 54.24  E-value: 1.42e-09
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 2020852016   153 QWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWN 192
Cdd:smart00320    1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
154-192 2.46e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 53.50  E-value: 2.46e-09
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2020852016  154 WRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWN 192
Cdd:pfam00400    1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
PTZ00420 PTZ00420
coronin; Provisional
 160-234 3.25e-05

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 48.02  E-value: 3.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  160 LRSHSGDVMDVAWSP-HDAWLASCSVDNTVVIW---------NAVKFPeiLATLRGHSGLVKGLTWDPVGKYI-ASQADD 228
Cdd:PTZ00420    70 LKGHTSSILDLQFNPcFSEILASGSEDLTIRVWeiphndesvKEIKDP--QCILKGHKKKISIIDWNPMNYYImCSSGFD 147


                   ....*.
gi 2020852016  229 RSLKVW 234
Cdd:PTZ00420   148 SFVNIW 153
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
531-750 4.28e-05

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 47.37  E-value: 4.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  531 NPQLLPLDSSTPNSFGASKPSTEPVATAGARP---------AGDTASKDSVNATSTPAASS---PSVLTTPSKIEPMKAF 598
Cdd:pfam03546  127 NSQVRPASTVGKGPSGKGANPAPPGKAGSAAPlvqvgkkeeDSESSSEESDSEGEAPPAATqakPSGKILQVRPASGPAK 206

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  599 DSRFTERSKATPGApaltsvTPTTVERLKEQNlvkdlrprDLLESSSDSDEKVPVAKPSSLSKRKLELEvETVEKKKKGR 678
Cdd:pfam03546  207 GAAPAPPQKAGPVA------TQVKAERSKEDS--------ESSEESSDSEEEAPAAATPAQAKPALKTP-QTKASPRKGT 271

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2020852016  679 P--RKESRLMPVSLSVQSPAALTTEKDTVCLSVPAPAlklpmPGPQRAFTLQVSSDPSMYIEVENEVTAVGGVK 750
Cdd:pfam03546  272 PitPTSAKVPPVRVGTPAPWKAGTVTSPACASSPAVA-----RGAQRPEEDSSSSEESESEEETAPAAAVGQAK 340
 
Name Accession Description Interval E-value
Hira pfam07569
TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are ...
 813-995 1.08e-57

TUP1-like enhancer of split; The Hira proteins are found in a range of eukaryotes and are implicated in the assembly of repressive chromatin. These proteins also contain pfam00400.


Pssm-ID: 462211  Cd Length: 221  Bit Score: 198.23  E-value: 1.08e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  813 LHCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSILAGS---------DMTVSQILLTQHGIPVMNLSDGKAYCFNPS 883
Cdd:pfam07569   17 LECSGSYLLAVTSVGLLYVWDIKKQKALLPPVSLAPLLDSSsrysdkltrAPTITSASLTSNGVPIVTLSNGDGYLYDKS 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  884 LSTWNLVSDKQDSLA-QCADFRSSLPPQDAMLCSGPLAIVQ----------GRASTSGRQAARLFSVPHVVQQET--TLA 950
Cdd:pfam07569   97 LETWLRISDSWWALGsQYWDSTGSSRSSSQSSAAGILSFLErktneellrkGRGRLLQRLAKTLLMKEGFENFETvvTLA 176

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2020852016  951 YLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDL 995
Cdd:pfam07569  177 HLENRLAAALLLGSPDEYRHWLLMYAKRLAEEGLKGRLRELCKEL 221
WD40 COG2319
WD40 repeat [General function prediction only];
8-385 7.06e-42

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 158.92  E-value: 7.06e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016    8 AALPAPLLRPRRAASLRAVAARPGQLPRVGGapergGPGKPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMSPvlqedde 87
Cdd:COG2319     87 SPDGRLLASASADGTVRLWDLATGLLLRTLT-----GHTGAVRSVAFSPDGKTLASGS---ADGTVRLWDLAT------- 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   88 kdeniPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWkratyigpstvfgssgklaNVEQWRCVSILRSHSGDV 167
Cdd:COG2319    152 -----GKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLW-------------------DLATGKLLRTLTGHTGAV 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  168 MDVAWSPHDAWLASCSVDNTVVIWNaVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITk 247
Cdd:COG2319    208 RSVAFSPDGKLLASGSADGTVRLWD-LATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLT- 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  248 pfdecGGTTHVLRLSWSPDGHYLVSAhamnNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSSAkps 327
Cdd:COG2319    286 -----GHSGGVNSVAFSPDGKLLASG----SDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP--------DGKTL--- 345

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2020852016  328 cpycccAVGSKDRSLSVWLTCLKRPLVVIHElFDKSIMDISWTLNGLGILVCSMDGSV 385
Cdd:COG2319    346 ------ASGSDDGTVRLWDLATGELLRTLTG-HTGAVTSVAFSPDGRTLASGSADGTV 396
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 44-385 7.08e-42

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 155.19  E-value: 7.08e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   44 GPGKPIFSVDIHPDGTKFATGGQgqdSGKVVIWNMSPVLQEDDEKdenipkmlcqmdNHLACVNCVRWSNSGMYLASGGD 123
Cdd:cd00200      7 GHTGGVTCVAFSPDGKLLATGSG---DGTIKVWDLETGELLRTLK------------GHTGPVRDVAASADGTYLASGSS 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  124 DKLIMVWkratyigpstvfgssgklaNVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFpEILATL 203
Cdd:cd00200     72 DKTIRLW-------------------DLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETG-KCLTTL 131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  204 RGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSItkpfdecggTTH---VLRLSWSPDGHYLVSAhAMNNsg 280
Cdd:cd00200    132 RGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATL---------TGHtgeVNSVAFSPDGEKLLSS-SSDG-- 199

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  281 pTAQIIEREGWKTNMDFVGHRKAVTVVKFNP--KIFkkkqkngssakpscpycccAVGSKDRSLSVWLTCLKRPLVVI-- 356
Cdd:cd00200    200 -TIKLWDLSTGKCLGTLRGHENGVNSVAFSPdgYLL-------------------ASGSEDGTIRVWDLRTGECVQTLsg 259

                          330       340
                   ....*....|....*....|....*....
gi 2020852016  357 HElfdKSIMDISWTLNGLGILVCSMDGSV 385
Cdd:cd00200    260 HT---NSVTSLAWSPDGKRLASGSADGTI 285
WD40 COG2319
WD40 repeat [General function prediction only];
12-400 3.71e-33

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 133.11  E-value: 3.71e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   12 APLLRPRRAASLRAVAARPGQLPRVGGAPERGGPGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDekden 91
Cdd:COG2319      2 LSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLG----- 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   92 ipkmlcqmdnHLACVNCVRWSNSGMYLASGGDDKLIMVWkratyigpstvfgssgklaNVEQWRCVSILRSHSGDVMDVA 171
Cdd:COG2319     77 ----------HTAAVLSVAFSPDGRLLASASADGTVRLW-------------------DLATGLLLRTLTGHTGAVRSVA 127

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  172 WSPHDAWLASCSVDNTVVIWNAVKfPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITkpfde 251
Cdd:COG2319    128 FSPDGKTLASGSADGTVRLWDLAT-GKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT----- 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  252 cGGTTHVLRLSWSPDGHYLVSAHAmnnsGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSSAkpscpyc 331
Cdd:COG2319    202 -GHTGAVRSVAFSPDGKLLASGSA----DGTVRLWDLATGKLLRTLTGHSGSVRSVAFSP--------DGRLL------- 261

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2020852016  332 ccAVGSKDRSLSVWLTCLKRPLVVIHELFDkSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLS 400
Cdd:COG2319    262 --ASGSADGTVRLWDLATGELLRTLTGHSG-GVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 327
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 102-389 6.16e-33

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 129.38  E-value: 6.16e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  102 HLACVNCVRWSNSGMYLASGGDDKLIMVWkratyigpstvfgssgklaNVEQWRCVSILRSHSGDVMDVAWSPHDAWLAS 181
Cdd:cd00200      8 HTGGVTCVAFSPDGKLLATGSGDGTIKVW-------------------DLETGELLRTLKGHTGPVRDVAASADGTYLAS 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  182 CSVDNTVVIWNaVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITkpfdecGGTTHVLRL 261
Cdd:cd00200     69 GSSDKTIRLWD-LETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLR------GHTDWVNSV 141

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  262 SWSPDGHYLVSAHAMNnsgpTAQIIEREGWKTNMDFVGHRKAVTVVKFNPkifkkkqkNGSSakpscpyccCAVGSKDRS 341
Cdd:cd00200    142 AFSPDGTFVASSSQDG----TIKLWDLRTGKCVATLTGHTGEVNSVAFSP--------DGEK---------LLSSSSDGT 200

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 2020852016  342 LSVWLTCLKRPLVVIHElFDKSIMDISWTLNGLGILVCSMDGSVAFLD 389
Cdd:cd00200    201 IKLWDLSTGKCLGTLRG-HENGVNSVAFSPDGYLLASGSEDGTIRVWD 247
WD40 COG2319
WD40 repeat [General function prediction only];
44-236 1.43e-31

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 128.49  E-value: 1.43e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   44 GPGKPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMSPvlqeddekdeniPKMLCQMDNHLACVNCVRWSNSGMYLASGGD 123
Cdd:COG2319    202 GHTGAVRSVAFSPDGKLLASGS---ADGTVRLWDLAT------------GKLLRTLTGHSGSVRSVAFSPDGRLLASGSA 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  124 DKLIMVWKRATYIGPSTVFGSSG-----------------------KLANVEQWRCVSILRSHSGDVMDVAWSPHDAWLA 180
Cdd:COG2319    267 DGTVRLWDLATGELLRTLTGHSGgvnsvafspdgkllasgsddgtvRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLA 346

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2020852016  181 SCSVDNTVVIWNaVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRT 236
Cdd:COG2319    347 SGSDDGTVRLWD-LATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDL 401
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 47-235 4.21e-28

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 115.51  E-value: 4.21e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   47 KPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMSPvlqeddekdeniPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKL 126
Cdd:cd00200     94 SYVSSVAFSPDGRILSSSS---RDKTIKVWDVET------------GKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGT 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  127 IMVW------KRATYIG-------------PSTVFGSSG----KLANVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCS 183
Cdd:cd00200    159 IKLWdlrtgkCVATLTGhtgevnsvafspdGEKLLSSSSdgtiKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGS 238

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2020852016  184 VDNTVVIWNAVKFpEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWR 235
Cdd:cd00200    239 EDGTIRVWDLRTG-ECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 156-405 7.49e-25

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 105.88  E-value: 7.49e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  156 CVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNaVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWr 235
Cdd:cd00200      1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWD-LETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLW- 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  236 tlDWQLETSITKPFDECGGtthVLRLSWSPDGHYLVSAHAMNnsgpTAQIIEREGWKTNMDFVGHRKAVTVVKFNPkifk 315
Cdd:cd00200     79 --DLETGECVRTLTGHTSY---VSSVAFSPDGRILSSSSRDK----TIKVWDVETGKCLTTLRGHTDWVNSVAFSP---- 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  316 kkqkNGSSAkpscpycccAVGSKDRSLSVW-LTCLKrpLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDE 394
Cdd:cd00200    146 ----DGTFV---------ASSSQDGTIKLWdLRTGK--CVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGK 210

                          250
                   ....*....|.
gi 2020852016  395 LGDPLSEEEKS 405
Cdd:cd00200    211 CLGTLRGHENG 221
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 153-192 1.42e-09

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 54.24  E-value: 1.42e-09
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 2020852016   153 QWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWN 192
Cdd:smart00320    1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
154-192 2.46e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 53.50  E-value: 2.46e-09
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2020852016  154 WRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWN 192
Cdd:pfam00400    1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 COG2319
WD40 repeat [General function prediction only];
44-134 4.51e-07

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 53.38  E-value: 4.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016   44 GPGKPIFSVDIHPDGTKFATGGqgqDSGKVVIWNMSPVLQeddekdenipkmLCQMDNHLACVNCVRWSNSGMYLASGGD 123
Cdd:COG2319    328 GHTGAVRSVAFSPDGKTLASGS---DDGTVRLWDLATGEL------------LRTLTGHTGAVTSVAFSPDGRTLASGSA 392

                           90
                   ....*....|.
gi 2020852016  124 DKLIMVWKRAT 134
Cdd:COG2319    393 DGTVRLWDLAT 403
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 94-131 1.79e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 45.38  E-value: 1.79e-06
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 2020852016    94 KMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWK 131
Cdd:smart00320    3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 198-234 3.22e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 44.61  E-value: 3.22e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 2020852016   198 EILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVW 234
Cdd:smart00320    3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
WD40 pfam00400
WD domain, G-beta repeat;
94-130 1.86e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 42.72  E-value: 1.86e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2020852016   94 KMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVW 130
Cdd:pfam00400    2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
WD40 pfam00400
WD domain, G-beta repeat;
198-234 2.70e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.95  E-value: 2.70e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2020852016  198 EILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVW 234
Cdd:pfam00400    2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
PTZ00420 PTZ00420
coronin; Provisional
 160-234 3.25e-05

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 48.02  E-value: 3.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  160 LRSHSGDVMDVAWSP-HDAWLASCSVDNTVVIW---------NAVKFPeiLATLRGHSGLVKGLTWDPVGKYI-ASQADD 228
Cdd:PTZ00420    70 LKGHTSSILDLQFNPcFSEILASGSEDLTIRVWeiphndesvKEIKDP--QCILKGHKKKISIIDWNPMNYYImCSSGFD 147


                   ....*.
gi 2020852016  229 RSLKVW 234
Cdd:PTZ00420   148 SFVNIW 153
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
531-750 4.28e-05

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 47.37  E-value: 4.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  531 NPQLLPLDSSTPNSFGASKPSTEPVATAGARP---------AGDTASKDSVNATSTPAASS---PSVLTTPSKIEPMKAF 598
Cdd:pfam03546  127 NSQVRPASTVGKGPSGKGANPAPPGKAGSAAPlvqvgkkeeDSESSSEESDSEGEAPPAATqakPSGKILQVRPASGPAK 206

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  599 DSRFTERSKATPGApaltsvTPTTVERLKEQNlvkdlrprDLLESSSDSDEKVPVAKPSSLSKRKLELEvETVEKKKKGR 678
Cdd:pfam03546  207 GAAPAPPQKAGPVA------TQVKAERSKEDS--------ESSEESSDSEEEAPAAATPAQAKPALKTP-QTKASPRKGT 271

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2020852016  679 P--RKESRLMPVSLSVQSPAALTTEKDTVCLSVPAPAlklpmPGPQRAFTLQVSSDPSMYIEVENEVTAVGGVK 750
Cdd:pfam03546  272 PitPTSAKVPPVRVGTPAPWKAGTVTSPACASSPAVA-----RGAQRPEEDSSSSEESESEEETAPAAAVGQAK 340
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 162-278 1.09e-04

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 46.57  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020852016  162 SHSGDVMD--VAWSPHDAWLASCS-VDNTVVIW----NAVKFPEILATlrGHSGLVKGLTWDPVGKYIASQADDRSLKVw 234
Cdd:COG4946    338 TNTPGVRErlPAWSPDGKSIAYFSdASGEYELYiapaDGSGEPKQLTL--GDLGRVFNPVWSPDGKKIAFTDNRGRLWV- 414

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2020852016  235 rtLDwqLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNN 278
Cdd:COG4946    415 --VD--LASGKVRKVDTDGYGDGISDLAWSPDSKWLAYSKPGPN 454
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 44-77 9.37e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 34.98  E-value: 9.37e-03
                            10        20        30
                    ....*....|....*....|....*....|....
gi 2020852016    44 GPGKPIFSVDIHPDGTKFATGGqgqDSGKVVIWN 77
Cdd:smart00320   10 GHTGPVTSVAFSPDGKYLASGS---DDGTIKLWD 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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