uncharacterized protein LOC123038121 [Drosophila rhopaloa]
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
ps-ssRNAv_RdRp-like super family | cl40470 | conserved catalytic core domain of RNA-dependent RNA polymerase (RdRp) from the positive-sense ... |
457-671 | 1.55e-60 | ||||
conserved catalytic core domain of RNA-dependent RNA polymerase (RdRp) from the positive-sense single-stranded RNA [(+)ssRNA] viruses and closely related viruses; This family contains the catalytic core domain of RdRp of RNA viruses which belong to Group IV of the Baltimore classification system, and are a group of related viruses that have positive-sense (+), single-stranded (ss) genomes made of ribonucleic acid (RNA). RdRp (also known as RNA replicase) catalyzes the replication of RNA from an RNA template; specifically, it catalyzes the synthesis of the RNA strand complementary to a given RNA template. The Baltimore Classification is divided into 7 classes, 3 of which include RNA viruses: Group IV (+) RNA viruses, Group III double-stranded (ds) RNA viruses, and Group V negative-sense (-) RNA viruses. Baltimore groups of viruses differ with respect to the nature of their genome (i.e., the nucleic acid form that is packaged into virions) and correspond to distinct strategies of genome replication and expression. (+) viral RNA is similar to mRNA and thus can be immediately translated by the host cell. (+)ssRNA viruses can also produce (+) copies of the genome from (-) strands of an intermediate dsRNA genome. This acts as both a transcription and a replication process since the replicated RNA is also mRNA. RdRps belong to the expansive class of polymerases containing so-called palm catalytic domains along with the accessory fingers and thumb domains. All RdRps also have six conserved structural motifs (A-F), located in its majority in the palm subdomain (A-E motifs) and the F motif is located on the finger subdomain. All these motifs have been shown to be implicated in RdRp fidelity such as processes of correct incorporation and reorganization of nucleotides. In addition to Group IV viruses, this model also includes Picobirnaviruses (PBVs), members of the family Picobirnaviridae of dsRNA viruses (Baltimore classification Group III), which are bi-segmented dsRNA viruses. The phylogenetic tree of the RdRps of RNA viruses (realm Riboviria) showed that picobirnaviruses are embedded in the branch of diverse (+)RNA viruses; sometimes they are collectively referred to as the picornavirus supergroup. RdRps of members of the family Permutatetraviridae, a distinct group of RNA viruses that encompass a circular permutation within the RdRp palm domain, are not included in this model. The actual alignment was detected with superfamily member cd01644: Pssm-ID: 477363 Cd Length: 213 Bit Score: 206.77 E-value: 1.55e-60
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Peptidase_A17 | pfam05380 | Pao retrotransposon peptidase; Corresponds to Merops family A17. These proteins are homologous ... |
686-859 | 1.78e-52 | ||||
Pao retrotransposon peptidase; Corresponds to Merops family A17. These proteins are homologous to aspartic proteinases encoded by retroposons and retroviruses. : Pssm-ID: 461634 Cd Length: 162 Bit Score: 181.56 E-value: 1.78e-52
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DUF1759 super family | cl04160 | Protein of unknown function (DUF1759); This is a family of proteins of unknown function. Most ... |
109-230 | 9.74e-16 | ||||
Protein of unknown function (DUF1759); This is a family of proteins of unknown function. Most of the members are gag-polyproteins. The actual alignment was detected with superfamily member pfam03564: Pssm-ID: 281552 Cd Length: 148 Bit Score: 75.95 E-value: 9.74e-16
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DUF5641 super family | cl40017 | Family of unknown function (DUF5641); This presumed domain is found in a range of ... |
1364-1412 | 1.59e-13 | ||||
Family of unknown function (DUF5641); This presumed domain is found in a range of retrotransposon polyproteins. The actual alignment was detected with superfamily member pfam18701: Pssm-ID: 465838 Cd Length: 94 Bit Score: 67.52 E-value: 1.59e-13
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Integrase_H2C2 | pfam17921 | Integrase zinc binding domain; This zinc binding domain is found in a wide variety of ... |
1081-1136 | 1.36e-10 | ||||
Integrase zinc binding domain; This zinc binding domain is found in a wide variety of integrase proteins. : Pssm-ID: 465569 [Multi-domain] Cd Length: 58 Bit Score: 58.03 E-value: 1.36e-10
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Name | Accession | Description | Interval | E-value | ||||
RT_pepA17 | cd01644 | RT_pepA17: Reverse transcriptase (RTs) in retrotransposons. This subfamily represents the RT ... |
457-671 | 1.55e-60 | ||||
RT_pepA17: Reverse transcriptase (RTs) in retrotransposons. This subfamily represents the RT domain of a multifunctional enzyme. C-terminal to the RT domain is a domain homologous to aspartic proteinases (corresponding to Merops family A17) encoded by retrotransposons and retroviruses. RT catalyzes DNA replication from an RNA template and is responsible for the replication of retroelements. Pssm-ID: 238822 Cd Length: 213 Bit Score: 206.77 E-value: 1.55e-60
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Peptidase_A17 | pfam05380 | Pao retrotransposon peptidase; Corresponds to Merops family A17. These proteins are homologous ... |
686-859 | 1.78e-52 | ||||
Pao retrotransposon peptidase; Corresponds to Merops family A17. These proteins are homologous to aspartic proteinases encoded by retroposons and retroviruses. Pssm-ID: 461634 Cd Length: 162 Bit Score: 181.56 E-value: 1.78e-52
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DUF1759 | pfam03564 | Protein of unknown function (DUF1759); This is a family of proteins of unknown function. Most ... |
109-230 | 9.74e-16 | ||||
Protein of unknown function (DUF1759); This is a family of proteins of unknown function. Most of the members are gag-polyproteins. Pssm-ID: 281552 Cd Length: 148 Bit Score: 75.95 E-value: 9.74e-16
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DUF5641 | pfam18701 | Family of unknown function (DUF5641); This presumed domain is found in a range of ... |
1364-1412 | 1.59e-13 | ||||
Family of unknown function (DUF5641); This presumed domain is found in a range of retrotransposon polyproteins. Pssm-ID: 465838 Cd Length: 94 Bit Score: 67.52 E-value: 1.59e-13
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Integrase_H2C2 | pfam17921 | Integrase zinc binding domain; This zinc binding domain is found in a wide variety of ... |
1081-1136 | 1.36e-10 | ||||
Integrase zinc binding domain; This zinc binding domain is found in a wide variety of integrase proteins. Pssm-ID: 465569 [Multi-domain] Cd Length: 58 Bit Score: 58.03 E-value: 1.36e-10
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Name | Accession | Description | Interval | E-value | ||||
RT_pepA17 | cd01644 | RT_pepA17: Reverse transcriptase (RTs) in retrotransposons. This subfamily represents the RT ... |
457-671 | 1.55e-60 | ||||
RT_pepA17: Reverse transcriptase (RTs) in retrotransposons. This subfamily represents the RT domain of a multifunctional enzyme. C-terminal to the RT domain is a domain homologous to aspartic proteinases (corresponding to Merops family A17) encoded by retrotransposons and retroviruses. RT catalyzes DNA replication from an RNA template and is responsible for the replication of retroelements. Pssm-ID: 238822 Cd Length: 213 Bit Score: 206.77 E-value: 1.55e-60
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Peptidase_A17 | pfam05380 | Pao retrotransposon peptidase; Corresponds to Merops family A17. These proteins are homologous ... |
686-859 | 1.78e-52 | ||||
Pao retrotransposon peptidase; Corresponds to Merops family A17. These proteins are homologous to aspartic proteinases encoded by retroposons and retroviruses. Pssm-ID: 461634 Cd Length: 162 Bit Score: 181.56 E-value: 1.78e-52
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DUF1759 | pfam03564 | Protein of unknown function (DUF1759); This is a family of proteins of unknown function. Most ... |
109-230 | 9.74e-16 | ||||
Protein of unknown function (DUF1759); This is a family of proteins of unknown function. Most of the members are gag-polyproteins. Pssm-ID: 281552 Cd Length: 148 Bit Score: 75.95 E-value: 9.74e-16
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DUF5641 | pfam18701 | Family of unknown function (DUF5641); This presumed domain is found in a range of ... |
1364-1412 | 1.59e-13 | ||||
Family of unknown function (DUF5641); This presumed domain is found in a range of retrotransposon polyproteins. Pssm-ID: 465838 Cd Length: 94 Bit Score: 67.52 E-value: 1.59e-13
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Integrase_H2C2 | pfam17921 | Integrase zinc binding domain; This zinc binding domain is found in a wide variety of ... |
1081-1136 | 1.36e-10 | ||||
Integrase zinc binding domain; This zinc binding domain is found in a wide variety of integrase proteins. Pssm-ID: 465569 [Multi-domain] Cd Length: 58 Bit Score: 58.03 E-value: 1.36e-10
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RT_LTR | cd01647 | RT_LTR: Reverse transcriptases (RTs) from retrotransposons and retroviruses which have long ... |
471-607 | 2.57e-03 | ||||
RT_LTR: Reverse transcriptases (RTs) from retrotransposons and retroviruses which have long terminal repeats (LTRs) in their DNA copies but not in their RNA template. RT catalyzes DNA replication from an RNA template, and is responsible for the replication of retroelements. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs are present in a variety of mobile elements, including retrotransposons, retroviruses, group II introns, bacterial msDNAs, hepadnaviruses, and Caulimoviruses. Pssm-ID: 238825 Cd Length: 177 Bit Score: 40.27 E-value: 2.57e-03
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Blast search parameters | ||||
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