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Conserved domains on  [gi|2217356042|ref|XP_047273221|]
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polyadenylate-binding protein-interacting protein 2 isoform X1 [Homo sapiens]

Protein Classification

PABP-interacting PAM2 motif-containing protein( domain architecture ID 10537407)

PABP-interacting PAM2 motif-containing protein similar to human polyadenylate-binding protein-interacting protein 2 (PAIP2) that acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PAM2 pfam07145
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various ...
108-123 3.05e-05

Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for pfam00658. It has been found in a wide range of eukaryotic proteins. Strikingly, this motif appears to occur solely outside of globular domains.


:

Pssm-ID: 429316  Cd Length: 17  Bit Score: 38.36  E-value: 3.05e-05
                          10
                  ....*....|....*.
gi 2217356042 108 KSNLNPNAKEFVPGVK 123
Cdd:pfam07145   2 KSKLNPNAKEFVPSFK 17
 
Name Accession Description Interval E-value
PAM2 pfam07145
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various ...
108-123 3.05e-05

Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for pfam00658. It has been found in a wide range of eukaryotic proteins. Strikingly, this motif appears to occur solely outside of globular domains.


Pssm-ID: 429316  Cd Length: 17  Bit Score: 38.36  E-value: 3.05e-05
                          10
                  ....*....|....*.
gi 2217356042 108 KSNLNPNAKEFVPGVK 123
Cdd:pfam07145   2 KSKLNPNAKEFVPSFK 17
 
Name Accession Description Interval E-value
PAM2 pfam07145
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various ...
108-123 3.05e-05

Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for pfam00658. It has been found in a wide range of eukaryotic proteins. Strikingly, this motif appears to occur solely outside of globular domains.


Pssm-ID: 429316  Cd Length: 17  Bit Score: 38.36  E-value: 3.05e-05
                          10
                  ....*....|....*.
gi 2217356042 108 KSNLNPNAKEFVPGVK 123
Cdd:pfam07145   2 KSKLNPNAKEFVPSFK 17
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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