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protein chibby homolog 3 isoform X1 [Homo sapiens]
Cby_like and SMC_prok_B domain-containing protein( domain architecture ID 10164867)
Cby_like and SMC_prok_B domain-containing protein
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Cby_like | cd07429 | Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins; ... |
1-99 | 5.54e-35 | |||
Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins; Chibby(Cby) is a well-conserved nuclear protein that functions as part of the Wnt/beta-catenin signaling pathway. Specifically, Cby binds directly to beta-catenin by interacting with its central region, which harbors armadillo repeats. Cby-beta-catenin interactions may also involve 14-3-3 proteins. By competing with other binding partners of beta-catenin, the Tcf/Lef transcription factors, Cby inhibits transcriptional activation. Cby has been shown to play a role in adipocyte differentiation. The C-terminal region of Cby appears to contain an alpha-helical coiled-coil motif. : Pssm-ID: 143631 Cd Length: 108 Bit Score: 117.44 E-value: 5.54e-35
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Name | Accession | Description | Interval | E-value | |||
Cby_like | cd07429 | Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins; ... |
1-99 | 5.54e-35 | |||
Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins; Chibby(Cby) is a well-conserved nuclear protein that functions as part of the Wnt/beta-catenin signaling pathway. Specifically, Cby binds directly to beta-catenin by interacting with its central region, which harbors armadillo repeats. Cby-beta-catenin interactions may also involve 14-3-3 proteins. By competing with other binding partners of beta-catenin, the Tcf/Lef transcription factors, Cby inhibits transcriptional activation. Cby has been shown to play a role in adipocyte differentiation. The C-terminal region of Cby appears to contain an alpha-helical coiled-coil motif. Pssm-ID: 143631 Cd Length: 108 Bit Score: 117.44 E-value: 5.54e-35
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Chibby | pfam14645 | Chibby family; This family includes the eukaryotic chibby proteins. These proteins inhibit the ... |
3-106 | 8.98e-35 | |||
Chibby family; This family includes the eukaryotic chibby proteins. These proteins inhibit the wingless/Wnt pathway by binding to beta-catenin and inhibiting beta-catenin-mediated transcriptional activation. Chibby is Japanese for small, and is named after the RNAi phenotype seen in Drosophila. Pssm-ID: 464233 Cd Length: 113 Bit Score: 117.03 E-value: 8.98e-35
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Name | Accession | Description | Interval | E-value | |||
Cby_like | cd07429 | Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins; ... |
1-99 | 5.54e-35 | |||
Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins; Chibby(Cby) is a well-conserved nuclear protein that functions as part of the Wnt/beta-catenin signaling pathway. Specifically, Cby binds directly to beta-catenin by interacting with its central region, which harbors armadillo repeats. Cby-beta-catenin interactions may also involve 14-3-3 proteins. By competing with other binding partners of beta-catenin, the Tcf/Lef transcription factors, Cby inhibits transcriptional activation. Cby has been shown to play a role in adipocyte differentiation. The C-terminal region of Cby appears to contain an alpha-helical coiled-coil motif. Pssm-ID: 143631 Cd Length: 108 Bit Score: 117.44 E-value: 5.54e-35
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Chibby | pfam14645 | Chibby family; This family includes the eukaryotic chibby proteins. These proteins inhibit the ... |
3-106 | 8.98e-35 | |||
Chibby family; This family includes the eukaryotic chibby proteins. These proteins inhibit the wingless/Wnt pathway by binding to beta-catenin and inhibiting beta-catenin-mediated transcriptional activation. Chibby is Japanese for small, and is named after the RNAi phenotype seen in Drosophila. Pssm-ID: 464233 Cd Length: 113 Bit Score: 117.03 E-value: 8.98e-35
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Blast search parameters | ||||
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