NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2217377610|ref|XP_047279486|]
View 

methylglutaconyl-CoA hydratase, mitochondrial isoform X13 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 1-191 1.47e-69

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PRK07657:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 260  Bit Score: 212.29  E-value: 1.47e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   1 MSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAI 80
Cdd:PRK07657   74 MNEEQVRHAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLI 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  81 GMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDaayrKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE 160
Cdd:PRK07657  154 GVGRAKELIYTGRRISAQEAKEIGLVEFVVPAHLLEE----KAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIE 229

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2217377610 161 EACYAQTIPTKDRLEGLLAFKEKRPPRYKGE 191
Cdd:PRK07657  230 KQAYEGTIPTKDRLEGLQAFKEKRKPMYKGE 260
 
Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 1-191 1.47e-69

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 212.29  E-value: 1.47e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   1 MSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAI 80
Cdd:PRK07657   74 MNEEQVRHAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLI 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  81 GMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDaayrKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE 160
Cdd:PRK07657  154 GVGRAKELIYTGRRISAQEAKEIGLVEFVVPAHLLEE----KAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIE 229

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2217377610 161 EACYAQTIPTKDRLEGLLAFKEKRPPRYKGE 191
Cdd:PRK07657  230 KQAYEGTIPTKDRLEGLQAFKEKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 5-185 7.59e-46

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 151.09  E-value: 7.59e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   5 EVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSL 84
Cdd:COG1024    73 EARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLAR 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  85 AKELIFSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACY 164
Cdd:COG1024   153 AKELLLTGRRIDAEEALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAF 228

                         170       180
                  ....*....|....*....|.
gi 2217377610 165 AQTIPTKDRLEGLLAFKEKRP 185
Cdd:COG1024   229 AELFASEDAREGIAAFLEKRK 249
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 20-190 4.55e-33

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 118.23  E-value: 4.55e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 99
Cdd:pfam00378  84 LYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQE 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 100 AKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLA 179
Cdd:pfam00378 164 ALKWGLVDKVVPEDQ----LLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQA 239

                         170
                  ....*....|.
gi 2217377610 180 FKEKRPPRYKG 190
Cdd:pfam00378 240 FLEKRKPPWED 250
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 9-129 7.20e-29

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 106.11  E-value: 7.20e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   9 FVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKEL 88
Cdd:cd06558    78 FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARAREL 157

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2217377610  89 IFSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLARE 129
Cdd:cd06558   158 LLTGRRISAEEALELGLVDEVVPD----EELLAAALELARR 194
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 24-169 4.72e-09

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 54.84  E-value: 4.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  24 PVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 101
Cdd:TIGR02441 108 QKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAK 187

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217377610 102 AVGLISHVLEQNQEGdaaYRKALDLAREFLPQgpVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIP 169
Cdd:TIGR02441 188 KMGIVDQLVDPLGPG---LKPAEENTIEYLEE--VAVKFAQGLANGKLSINRDKGLVHKITQYVMTNP 250
 
Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 1-191 1.47e-69

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 212.29  E-value: 1.47e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   1 MSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAI 80
Cdd:PRK07657   74 MNEEQVRHAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLI 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  81 GMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDaayrKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE 160
Cdd:PRK07657  154 GVGRAKELIYTGRRISAQEAKEIGLVEFVVPAHLLEE----KAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIE 229

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2217377610 161 EACYAQTIPTKDRLEGLLAFKEKRPPRYKGE 191
Cdd:PRK07657  230 KQAYEGTIPTKDRLEGLQAFKEKRKPMYKGE 260
PLN02600 PLN02600
enoyl-CoA hydratase
 1-191 6.89e-68

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 207.73  E-value: 6.89e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   1 MSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAI 80
Cdd:PLN02600   65 MSPSEVQKFVNSLRSTFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLV 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  81 GMSLAKELIFSARVLDGKEAKAVGLISHVLeqnQEGDaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE 160
Cdd:PLN02600  145 GRSRAKELIFTGRRIGAREAASMGLVNYCV---PAGE-AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIE 220

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2217377610 161 EACYAQTIPTKDRLEGLLAFKEKRPPRYKGE 191
Cdd:PLN02600  221 EECYEQVLKTKDRLEGLAAFAEKRKPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 5-185 7.59e-46

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 151.09  E-value: 7.59e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   5 EVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSL 84
Cdd:COG1024    73 EARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLAR 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  85 AKELIFSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACY 164
Cdd:COG1024   153 AKELLLTGRRIDAEEALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAF 228

                         170       180
                  ....*....|....*....|.
gi 2217377610 165 AQTIPTKDRLEGLLAFKEKRP 185
Cdd:COG1024   229 AELFASEDAREGIAAFLEKRK 249
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
16-190 7.95e-42

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 141.42  E-value: 7.95e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  16 VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 95
Cdd:PRK05809   89 VFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMI 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  96 DGKEAKAVGLISHVLEQNQEGDAAYRkaldLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLE 175
Cdd:PRK05809  169 NAEEALRIGLVNKVVEPEKLMEEAKA----LANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTE 244

                         170
                  ....*....|....*
gi 2217377610 176 GLLAFKEKRPPRYKG 190
Cdd:PRK05809  245 GMTAFVEKREKNFKN 259
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 20-190 9.20e-36

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 125.65  E-value: 9.20e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 99
Cdd:PRK09674   88 LQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESITAQQ 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 100 AKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLA 179
Cdd:PRK09674  168 AQQAGLVSEVFPP----ELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGISA 243

                         170
                  ....*....|.
gi 2217377610 180 FKEKRPPRYKG 190
Cdd:PRK09674  244 FLEKRTPDFKG 254
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 20-190 4.55e-33

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 118.23  E-value: 4.55e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 99
Cdd:pfam00378  84 LYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQE 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 100 AKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLA 179
Cdd:pfam00378 164 ALKWGLVDKVVPEDQ----LLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQA 239

                         170
                  ....*....|.
gi 2217377610 180 FKEKRPPRYKG 190
Cdd:pfam00378 240 FLEKRKPPWED 250
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 16-190 6.79e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 118.05  E-value: 6.79e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  16 VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 95
Cdd:PRK06688   88 FLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPL 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  96 DGKEAKAVGLISHVLEQNqEGDAayrKALDLAREfLPQGP-VAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRL 174
Cdd:PRK06688  168 SAEEALRIGLVNRVVPAA-ELDA---EADAQAAK-LAAGPaSALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFR 242

                         170
                  ....*....|....*.
gi 2217377610 175 EGLLAFKEKRPPRYKG 190
Cdd:PRK06688  243 EGATAFIEKRKPDFTG 258
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 1-191 4.68e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 113.19  E-value: 4.68e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   1 MSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAI 80
Cdd:PRK07658   71 TEAEQATELAQLGQVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYV 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  81 GMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE 160
Cdd:PRK07658  151 GKAKALEMMLTSEPITGAEALKWGLVNGVFPEET----LLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKRE 226

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2217377610 161 EACYAQTIPTKDRLEGLLAFKEKRPPRYKGE 191
Cdd:PRK07658  227 AKIFGEVFTSEDAKEGVQAFLEKRKPSFSGK 257
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
20-191 2.38e-30

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 111.60  E-value: 2.38e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 99
Cdd:PRK09245   99 LYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFTGDAIDAAT 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 100 AKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLA 179
Cdd:PRK09245  179 ALEWGLVSRVVPADQLLPA----ARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAYQALAHHTADHREAVDA 254

                         170
                  ....*....|..
gi 2217377610 180 FKEKRPPRYKGE 191
Cdd:PRK09245  255 FLEKRPPVFTGR 266
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 20-191 3.90e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 110.91  E-value: 3.90e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 99
Cdd:PRK08138   94 IAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALTGCMVPAPE 173

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 100 AKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLA 179
Cdd:PRK08138  174 ALAIGLVSEVVEDEQ----TLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQKEGMDA 249

                         170
                  ....*....|..
gi 2217377610 180 FKEKRPPRYKGE 191
Cdd:PRK08138  250 FLEKRKPAYKGK 261
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 19-189 1.89e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 108.98  E-value: 1.89e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  19 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 98
Cdd:PRK05862   89 KVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAA 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  99 EAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPqgpvAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLL 178
Cdd:PRK05862  169 EAERAGLVSRVVPADKLLDEALAAATTIASFSLP----AVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMA 244

                         170
                  ....*....|.
gi 2217377610 179 AFKEKRPPRYK 189
Cdd:PRK05862  245 AFVEKRKPVFK 255
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 9-129 7.20e-29

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 106.11  E-value: 7.20e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   9 FVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKEL 88
Cdd:cd06558    78 FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARAREL 157

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2217377610  89 IFSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLARE 129
Cdd:cd06558   158 LLTGRRISAEEALELGLVDEVVPD----EELLAAALELARR 194
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
26-191 1.87e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 99.02  E-value: 1.87e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  26 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGL 105
Cdd:PRK07799  102 PLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEAKEIGL 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 106 ISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRP 185
Cdd:PRK07799  182 IGHVVPDGQ----ALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEGPRAFAEKRA 257


                  ....*.
gi 2217377610 186 PRYKGE 191
Cdd:PRK07799  258 PNFQGR 263
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 26-190 2.57e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 95.88  E-value: 2.57e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  26 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGL 105
Cdd:PRK06494   96 PIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREGLELGF 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 106 ISHVLEQnQEGDAAyrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLvtglaiEEACYAQT--------IPTKDRLEGL 177
Cdd:PRK06494  176 VNEVVPA-GELLAA---AERWADDILACSPLSIRASKQAVYRGLEVSL------EEAITAQRdypavearRASQDYIEGP 245

                         170
                  ....*....|...
gi 2217377610 178 LAFKEKRPPRYKG 190
Cdd:PRK06494  246 KAFAEKRPPRWKG 258
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 27-189 2.83e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 95.76  E-value: 2.83e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  27 TIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLI 106
Cdd:PRK09076   98 SIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAATALRIGLV 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 107 SHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPP 186
Cdd:PRK09076  178 EEVVEKGEAREA----ALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNAFLEKRAP 253


                  ...
gi 2217377610 187 RYK 189
Cdd:PRK09076  254 QWK 256
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
22-189 6.97e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 94.56  E-value: 6.97e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  22 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 101
Cdd:PRK07509  100 RLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELTYTARVFSAEEAL 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 102 AVGLISHVLEQnqegdaAYRKALDLAREFLPQGPVAMRVAKLAINQgMEVDLVTGLAIEEACY-AQTIPTKDRLEGLLAF 180
Cdd:PRK07509  180 ELGLVTHVSDD------PLAAALALAREIAQRSPDAIAAAKRLINR-SWTASVRALLARESVEqIRLLLGKNQKIAVKAQ 252


                  ....*....
gi 2217377610 181 KEKRPPRYK 189
Cdd:PRK07509  253 MKKRAPKFL 261
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 20-190 3.80e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 92.85  E-value: 3.80e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 99
Cdd:PRK06127  102 LADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDAAE 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 100 AKAVGLISHVLEqNQEGDAAyrkALDLAREFLPQGPVAMRVAKLAINQ----GMEVDLVTGLAIEEACYAqtipTKDRLE 175
Cdd:PRK06127  182 ALRIGLVHRVTA-ADDLETA---LADYAATIAGNAPLTLRAAKRAIAEllkdEPERDMAACQALVAACFD----SEDYRE 253

                         170
                  ....*....|....*
gi 2217377610 176 GLLAFKEKRPPRYKG 190
Cdd:PRK06127  254 GRAAFMEKRKPVFKG 268
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
9-188 6.98e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 89.43  E-value: 6.98e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   9 FVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKEL 88
Cdd:PRK05980   85 FVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALEL 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  89 IFSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTI 168
Cdd:PRK05980  165 LLTGDAFSAERALEIGLVNAVVPH----EELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMA 240

                         170       180
                  ....*....|....*....|
gi 2217377610 169 PTKDRLEGLLAFKEKRPPRY 188
Cdd:PRK05980  241 GSADLREGLAAWIERRRPAY 260
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 12-190 4.48e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 87.36  E-value: 4.48e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  12 KIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMG----------LVETKLAiipggggtqRLPRAIG 81
Cdd:PRK06144   90 RIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGfpiartlgncLSMSNLA---------RLVALLG 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  82 MSLAKELIFSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEE 161
Cdd:PRK06144  161 AARVKDMLFTARLLEAEEALAAGLVNEVVED----AALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDGDDLIR 236

                         170       180
                  ....*....|....*....|....*....
gi 2217377610 162 ACYAqtipTKDRLEGLLAFKEKRPPRYKG 190
Cdd:PRK06144  237 MCYM----SEDFREGVEAFLEKRPPKWKG 261
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
26-191 5.47e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 86.97  E-value: 5.47e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  26 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGL 105
Cdd:PRK08252   93 PLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTAERAHELGL 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 106 ISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRP 185
Cdd:PRK08252  173 VNRLTEPGQALDA----ALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFTSADAKEGATAFAEKRA 248


                  ....*.
gi 2217377610 186 PRYKGE 191
Cdd:PRK08252  249 PVWTGK 254
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 26-190 2.40e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 85.83  E-value: 2.40e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  26 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGL 105
Cdd:PRK08260  115 PVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVGLQTALEWVYSGRVFDAQEALDGGL 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 106 ISHVLEQNQEGDAAYrkalDLAREFLPQ-GPVAMRVAK------LAINQGMEVDLVTGLAIeeacYAQTIpTKDRLEGLL 178
Cdd:PRK08260  195 VRSVHPPDELLPAAR----ALAREIADNtSPVSVALTRqmmwrmAGADHPMEAHRVDSRAI----YSRGR-SGDGKEGVS 265

                         170
                  ....*....|..
gi 2217377610 179 AFKEKRPPRYKG 190
Cdd:PRK08260  266 SFLEKRPAVFPG 277
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 23-190 2.61e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 85.53  E-value: 2.61e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  23 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKA 102
Cdd:PRK06210  107 LRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANALDLLLSARTFYAEEALR 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 103 VGLISHVLEQNQEGDAAYRKALDLAREFlpqGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKE 182
Cdd:PRK06210  187 LGLVNRVVPPDELMERTLAYAEDLARNV---SPASMAVIKRQLYEDAFQTLAEATARANREMHESLQRPDFIEGVASFLE 263


                  ....*...
gi 2217377610 183 KRPPRYKG 190
Cdd:PRK06210  264 KRPPRFPG 271
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
12-190 3.14e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 85.03  E-value: 3.14e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  12 KIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFS 91
Cdd:PRK06142   97 RLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGHLRELALT 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  92 ARVLDGKEAKAVGLISHVLEqnqEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTK 171
Cdd:PRK06142  177 GRDIDAAEAEKIGLVNRVYD---DADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAAMLPSK 253

                         170
                  ....*....|....*....
gi 2217377610 172 DRLEGLLAFKEKRPPRYKG 190
Cdd:PRK06142  254 DLTEAIAAHMEKRPPEFTG 272
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
1-119 1.25e-19

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 85.68  E-value: 1.25e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   1 MSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAI 80
Cdd:PRK11730   79 APEEELSQWLHFANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLI 158

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2217377610  81 GMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAA 119
Cdd:PRK11730  159 GADNALEWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAA 197
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 17-191 7.22e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 81.11  E-value: 7.22e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  17 INDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLD 96
Cdd:PRK08140   92 VRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLALLGEKLS 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  97 GKEAKAVGLISHVLEqnqegDAAYR-KALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLE 175
Cdd:PRK08140  172 AEQAEQWGLIWRVVD-----DAALAdEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADYAE 246

                         170
                  ....*....|....*.
gi 2217377610 176 GLLAFKEKRPPRYKGE 191
Cdd:PRK08140  247 GVSAFLEKRAPRFTGR 262
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 14-146 1.51e-18

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 79.88  E-value: 1.51e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  14 RAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSAR 93
Cdd:PRK05869   89 QQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGR 168

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2217377610  94 VLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAIN 146
Cdd:PRK05869  169 FFDAEEALALGLIDEMVAP----DDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 20-191 1.67e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 80.35  E-value: 1.67e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPggggTQRLP---RAIGMSLAKELIFSARVLD 96
Cdd:PRK05995   95 IYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGERAARRYFLTAERFD 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  97 GKEAKAVGLISHVLEQnQEGDAayrKALDLAREFLPQGPVAMRVAKLAINQgmevdlVTGLAIEEACYAQTIP------- 169
Cdd:PRK05995  171 AAEALRLGLVHEVVPA-EALDA---KVDELLAALVANSPQAVRAGKRLVRD------VAGRPIDAALIADTASrialira 240

                         170       180
                  ....*....|....*....|..
gi 2217377610 170 TKDRLEGLLAFKEKRPPRYKGE 191
Cdd:PRK05995  241 TEEAREGVAAFLEKRKPAWRGR 262
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 13-191 2.32e-18

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 80.07  E-value: 2.32e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  13 IRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA 92
Cdd:PRK11423   85 LRQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTA 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  93 RVLDGKEAKAVGLISHVLEQNQEGDAAYrkalDLAREFLPQGPVAMRVAK-----LAINQGMEVDL---VTGLAieeacy 164
Cdd:PRK11423  165 SPITAQRALAVGILNHVVEVEELEDFTL----QMAHHISEKAPLAIAVIKeqlrvLGEAHPMNPDEferIQGLR------ 234

                         170       180
                  ....*....|....*....|....*..
gi 2217377610 165 AQTIPTKDRLEGLLAFKEKRPPRYKGE 191
Cdd:PRK11423  235 RAVYDSEDYQEGMNAFLEKRKPVFVGH 261
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
22-191 3.70e-18

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 79.35  E-value: 3.70e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  22 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 101
Cdd:PRK03580   92 DLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEEAL 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 102 AVGLISHVLEQNQEGDAAYrkalDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIP----TKDRLEGL 177
Cdd:PRK03580  172 RWGIVNRVVPQAELMDRAR----ELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRSGVLKHYPsvlhSEDALEGP 247

                         170
                  ....*....|....
gi 2217377610 178 LAFKEKRPPRYKGE 191
Cdd:PRK03580  248 RAFAEKRDPVWKGR 261
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
46-190 6.48e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 78.46  E-value: 6.48e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  46 CDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEgdaaYRKALD 125
Cdd:PRK06563  114 ADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQEALRLGLVQEVVPPGEQ----LERAIE 189

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217377610 126 LAREFLPQGPVAMRV----AKLAINQGmevdlvtglaiEEACYAQTIPTKDRL-------EGLLAFKEKRPPRYKG 190
Cdd:PRK06563  190 LAERIARAAPLGVQAtlasARAAVREG-----------EAAAAAQLPPELRPLftsedakEGVQAFLERRPARFKG 254
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 17-190 1.35e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 77.73  E-value: 1.35e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  17 INDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLD 96
Cdd:PRK07511   91 IRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPIS 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  97 GKEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEG 176
Cdd:PRK07511  171 AERLHALGVVNRLAEPGQALAE----ALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEG 246

                         170
                  ....*....|....
gi 2217377610 177 LLAFKEKRPPRYKG 190
Cdd:PRK07511  247 IAAFLEKRAPDYKR 260
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
15-124 2.85e-17

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 78.78  E-value: 2.85e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  15 AVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA 92
Cdd:PRK11154   92 QLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKtvLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTG 171

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2217377610  93 RVLDGKEAKAVGLISHVLEQNQEGDAAYRKAL 124
Cdd:PRK11154  172 KQLRAKQALKLGLVDDVVPHSILLEVAVELAK 203
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
23-190 1.27e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 72.40  E-value: 1.27e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  23 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRaIGMSLAKELIFSARVLDGKEAKA 102
Cdd:PRK07468   99 LPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFMSARLFDAEEAVR 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 103 VGLISHVLEQNQEgDAAYRKALdlaREFLPQGPVAMRVAK-LAINQGMEVDlvtglaieEACYAQTI-------PTKDRL 174
Cdd:PRK07468  178 LGLLSRVVPAERL-DAAVEAEV---TPYLSCAPGAVAAAKaLVRALGAPID--------EAVIDATIealadtwETEEAR 245

                         170
                  ....*....|....*.
gi 2217377610 175 EGLLAFKEKRPPRYKG 190
Cdd:PRK07468  246 EGIAAFFDKRAPAWRG 261
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
15-184 5.41e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 70.82  E-value: 5.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  15 AVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARV 94
Cdd:PRK08150   83 RVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRV 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  95 LDGKEAKAVGLISHVLEQNQegdaAYRKALDLAR---EFLPQGPVAM-----RVAKLAINQGMEVDLVTglaieeACYAQ 166
Cdd:PRK08150  163 YDAQEGERLGLAQYLVPAGE----ALDKAMELARriaQNAPLTNFAVlnalpRIADMSADDGLFVESLM------AAVAQ 232

                         170
                  ....*....|....*....
gi 2217377610 167 TIP-TKDRLEgllAFKEKR 184
Cdd:PRK08150  233 SAPeAKERLR---AFLEKK 248
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
1-190 5.42e-15

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 71.15  E-value: 5.42e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   1 MSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETK--LAiipGG--GGTQRL 76
Cdd:PRK08258   90 MDMPELLAFTRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRvgLA---GAdmGACALL 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  77 PRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAReflpqGPV-AMRVAKLAINQgmEVDLVT 155
Cdd:PRK08258  167 PRIIGQGRASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAA-----GPTfAHGMTKTMLHQ--EWDMGL 239

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2217377610 156 GLAIEEACYAQTI--PTKDRLEGLLAFKEKRPPRYKG 190
Cdd:PRK08258  240 EEAIEAEAQAQAIcmQTEDFRRAYEAFVAKRKPVFEG 276
PLN02888 PLN02888
enoyl-CoA hydratase
 25-160 7.45e-15

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 70.55  E-value: 7.45e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  25 VPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVG 104
Cdd:PLN02888  100 KPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTAETAERWG 179

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217377610 105 LISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE 160
Cdd:PLN02888  180 LVNHVVEESE----LLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLE 231
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 20-162 1.91e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 66.54  E-value: 1.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 99
Cdd:PRK06190   90 WPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAAD 169

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217377610 100 AKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEA 162
Cdd:PRK06190  170 ALRAGLVTEVVPHDELLPR----ARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAE 228
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 13-191 2.69e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 66.21  E-value: 2.69e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  13 IRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA 92
Cdd:PRK07659   87 ISEIVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEG 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  93 RVLDGKEAKAVGLISHVLEqnQEGDAAYRKALDlarEFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKD 172
Cdd:PRK07659  167 KKLSATEALDLGLIDEVIG--GDFQTAAKQKIS---EWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKRAQYAMRQTAD 241

                         170
                  ....*....|....*....
gi 2217377610 173 RLEGLLAFKEKRPPRYKGE 191
Cdd:PRK07659  242 HKEGIRAFLEKRLPVFKGE 260
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 13-188 3.80e-13

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 66.08  E-value: 3.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  13 IRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA 92
Cdd:PLN02664  100 LQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELALTG 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  93 RVLDGKEAKAVGLISHVLEQNQEGDAAYRKaldLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKD 172
Cdd:PLN02664  180 RRFSGSEAKELGLVSRVFGSKEDLDEGVRL---IAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNSAMLVSDD 256

                         170
                  ....*....|....*.
gi 2217377610 173 RLEGLLAFKEKRPPRY 188
Cdd:PLN02664  257 LNEAVSAQIQKRKPVF 272
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
8-190 7.16e-13

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 65.14  E-value: 7.16e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   8 PFVSKIRavindiaNLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKE 87
Cdd:PRK05981   94 PFLRRLR-------NLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAME 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  88 LIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAReflpqGP-VAMRVAKLAINQGMEVDLVTGLAIEeaCYAQ 166
Cdd:PRK05981  167 LSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELAN-----GPtVALGLIRKLYWDSPENDFEEQLNLE--REAQ 239

                         170       180
                  ....*....|....*....|....*.
gi 2217377610 167 TIP--TKDRLEGLLAFKEKRPPRYKG 190
Cdd:PRK05981  240 RIAgkTEDFKEGVGAFLQKRPAQFKG 265
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
12-190 8.33e-13

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 64.72  E-value: 8.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  12 KIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIpggGGTQRLPRAIGMSLAKELIFS 91
Cdd:PRK06495   85 RTRECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGHSLTRRMMLT 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  92 ARVLDGKEAKAVGLISHVLeqnqEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTK 171
Cdd:PRK06495  162 GYRVPAAELYRRGVIEACL----PPEELMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAKTE 237

                         170
                  ....*....|....*....
gi 2217377610 172 DRLEGLLAFKEKRPPRYKG 190
Cdd:PRK06495  238 DAKEAQRAFLEKRPPVFKG 256
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 9-142 2.22e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 63.51  E-value: 2.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   9 FVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAiIPGGGGTQRLPRAIGMSLAKEL 88
Cdd:PRK06143   85 FISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWL 163

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2217377610  89 IFSARVLDGKEAKAVGLISHVLEqNQEGDAAYRKaldLAREFLPQGPVAMRVAK 142
Cdd:PRK06143  164 LLTGETIDAAQALAWGLVDRVVP-LAELDAAVER---LAASLAGCGPQALRQQK 213
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
14-190 1.45e-11

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 61.58  E-value: 1.45e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  14 RAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSAR 93
Cdd:PRK07327   96 RDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLLLCE 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  94 VLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREfLPQG-PVAMRVAKLAINQGMEV---DLVTGLAIEEACYAqtip 169
Cdd:PRK07327  176 PVSGEEAERIGLVSLAVDD----DELLPKALEVAER-LAAGsQTAIRWTKYALNNWLRMagpTFDTSLALEFMGFS---- 246

                         170       180
                  ....*....|....*....|.
gi 2217377610 170 TKDRLEGLLAFKEKRPPRYKG 190
Cdd:PRK07327  247 GPDVREGLASLREKRAPDFPG 267
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
23-160 6.46e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 59.52  E-value: 6.46e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  23 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKA 102
Cdd:PRK08259   92 LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDLILTGRPVDADEALA 171

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217377610 103 VGLISHVLEQNQEGDAAYRKALDLARefLPQgpVAMRVAKLAINQGMEVDLVTGLAIE 160
Cdd:PRK08259  172 IGLANRVVPKGQARAAAEELAAELAA--FPQ--TCLRADRLSALEQWGLPEEAALANE 225
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 9-190 4.05e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 56.96  E-value: 4.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610   9 FVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKEL 88
Cdd:PRK07854   71 FPDALIEMLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAM 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  89 IFSARVLDGKEAKAVGLIshvleqNQEGDAAyrKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTglAIEEACYAQTI 168
Cdd:PRK07854  151 LLGAEKLTAEQALATGMA------NRIGTLA--DAQAWAAEIAGLAPLALQHAKRVLNDDGAIEEAW--PAHKELFDKAW 220

                         170       180
                  ....*....|....*....|..
gi 2217377610 169 PTKDRLEGLLAFKEKRPPRYKG 190
Cdd:PRK07854  221 ASQDAIEAQVARIEKRPPKFQG 242
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 19-189 1.72e-09

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 55.67  E-value: 1.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  19 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 98
Cdd:PRK07396  102 LIRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCRQYDAQ 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  99 EAKAVGLISHV--LEQNQEgdaayrKALDLAREFLPQGPVAMRVAKLAINQgmEVDLVTGLAiEEACYAQTI--PTKDRL 174
Cdd:PRK07396  182 EALDMGLVNTVvpLADLEK------ETVRWCREMLQNSPMALRCLKAALNA--DCDGQAGLQ-ELAGNATMLfyMTEEAQ 252

                         170
                  ....*....|....*
gi 2217377610 175 EGLLAFKEKRPPRYK 189
Cdd:PRK07396  253 EGRNAFNEKRQPDFS 267
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 19-111 1.77e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 55.50  E-value: 1.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  19 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 98
Cdd:PRK05870   90 AVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAE 169

                          90
                  ....*....|...
gi 2217377610  99 EAKAVGLISHVLE 111
Cdd:PRK05870  170 AAVRHGLALMVAD 182
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 20-191 3.25e-09

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 54.56  E-value: 3.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAII---PGGGgtqrLPRAIGMSLAKELIFSARVLD 96
Cdd:PRK08139  100 IVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVA----LSRNVPRKQAMEMLLTGEFID 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  97 GKEAKAVGLISHVLEQNQEGDAAYRkaldLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEG 176
Cdd:PRK08139  176 AATAREWGLVNRVVPADALDAAVAR----LAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMMAEDAEEG 251

                         170
                  ....*....|....*
gi 2217377610 177 LLAFKEKRPPRYKGE 191
Cdd:PRK08139  252 IDAFLEKRPPEWRGR 266
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 24-169 4.72e-09

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 54.84  E-value: 4.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  24 PVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 101
Cdd:TIGR02441 108 QKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAK 187

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217377610 102 AVGLISHVLEQNQEGdaaYRKALDLAREFLPQgpVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIP 169
Cdd:TIGR02441 188 KMGIVDQLVDPLGPG---LKPAEENTIEYLEE--VAVKFAQGLANGKLSINRDKGLVHKITQYVMTNP 250
PLN02921 PLN02921
naphthoate synthase
 20-188 8.13e-09

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 54.02  E-value: 8.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 99
Cdd:PLN02921  157 IRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYTASE 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 100 AKAVGLISHVLEQNQ-EGDAAyrkalDLAREFLPQGPVAMRVAKLAINQGMevDLVTGLAiEEACYAQTI--PTKDRLEG 176
Cdd:PLN02921  237 ALKMGLVNTVVPLDElEGETV-----KWCREILRNSPTAIRVLKSALNAAD--DGHAGLQ-ELGGNATLLfyGSEEGNEG 308

                         170
                  ....*....|..
gi 2217377610 177 LLAFKEKRPPRY 188
Cdd:PLN02921  309 RTAYLEGRAPDF 320
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 46-153 2.77e-08

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 51.93  E-value: 2.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  46 CDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEgDAAYRKald 125
Cdd:PRK09120  126 CDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMTGETFTGRKAAEMGLVNESVPLAQL-RARTRE--- 201

                          90       100
                  ....*....|....*....|....*...
gi 2217377610 126 LAREFLPQGPVAMRVAKLAINQGMEVDL 153
Cdd:PRK09120  202 LAAKLLEKNPVVLRAAKDGFKRVRELTW 229
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 16-188 4.00e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 51.76  E-value: 4.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  16 VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKM-------GLVETKLaiipggGGTQRLPRAIGMSLAKEL 88
Cdd:PRK05864  101 VILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFraaginnGLTASEL------GLSYLLPRAIGSSRAFEI 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  89 IFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPqgpvAMRVAKLAINQGMEVDLVTGLAIEEAcYAQ-- 166
Cdd:PRK05864  175 MLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRP----GIELTKRTLWSGLDAASLEAHMQAEG-LGQlf 249

                         170       180
                  ....*....|....*....|...
gi 2217377610 167 -TIPTKDRLEGLLAFKEKRPPRY 188
Cdd:PRK05864  250 vRLLTANFEEAVAARAEKRPPVF 272
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 22-142 6.69e-08

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 51.07  E-value: 6.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  22 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 101
Cdd:PRK08788  119 GAGAISIALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEELH 198

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2217377610 102 AVGLISHVLEQNQeGDAAYRKALDLAREfLPQGPVAMRVAK 142
Cdd:PRK08788  199 DMGLVDVLVEDGQ-GEAAVRTFIRKSKR-KLNGWRAMLRAR 237
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 22-151 1.26e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 50.34  E-value: 1.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  22 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIipggGGTQRL--PRAIGMSLAKELIFSARVLDGKE 99
Cdd:PRK08290  116 DLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI----PGVEYFahPWELGPRKAKELLFTGDRLTADE 191

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217377610 100 AKAVGLISHV-----LEQnqegdaayrKALDLAREFLPQGPVAMRVAKLAINQGMEV 151
Cdd:PRK08290  192 AHRLGMVNRVvprdeLEA---------ETLELARRIAAMPPFGLRLTKRAVNQTLDA 239
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 20-191 3.36e-07

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 49.04  E-value: 3.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTqRLPRAIGMSLAKELIFSARVLDGKE 99
Cdd:PRK05674   97 LYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISP-FVVKAIGERAARRYALTAERFDGRR 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610 100 AKAVGLISHVLEQnQEGDAAYRKALDlarEFLPQGPVAMRVAKLAINQGMEVDLVTGL-AIEEACYAQTIPTKDRLEGLL 178
Cdd:PRK05674  176 ARELGLLAESYPA-AELEAQVEAWIA---NLLLNSPQALRASKDLLREVGDGELSPALrRYCENAIARIRVSAEGQEGLR 251

                         170
                  ....*....|...
gi 2217377610 179 AFKEKRPPRYKGE 191
Cdd:PRK05674  252 AFLEKRTPAWQTD 264
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 22-128 5.84e-07

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 48.04  E-value: 5.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  22 NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAK 101
Cdd:PRK07110   92 NCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLLTARYYRGAELK 171

                          90       100
                  ....*....|....*....|....*..
gi 2217377610 102 AVGLISHVLEQNQEGDAAYRKALDLAR 128
Cdd:PRK07110  172 KRGVPFPVLPRAEVLEKALELARSLAE 198
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
20-189 1.15e-06

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 47.71  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  20 IANLPVPTIAAIDGLALGGGLELALACDIRVAASS-AKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 98
Cdd:PRK08321  131 IRFMPKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYSAE 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  99 EAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINqgMEVD------LVTGLAIEEAcYAqtipTKD 172
Cdd:PRK08321  211 EAHDMGAVNAVVPHAELETE----ALEWAREINGKSPTAMRMLKYAFN--LTDDglvgqqLFAGEATRLA-YM----TDE 279

                         170
                  ....*....|....*..
gi 2217377610 173 RLEGLLAFKEKRPPRYK 189
Cdd:PRK08321  280 AQEGRDAFLEKRDPDWS 296
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 16-191 4.27e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 45.54  E-value: 4.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  16 VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELI----FS 91
Cdd:PRK06072   81 IIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVlggeFT 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  92 ArvldgKEAKAVGLISHVleqnqegDAAYRKALDLAREFLpQGPVAMRVA-KLAINQGMEVDLVTGLAIEEACYAQTIPT 170
Cdd:PRK06072  161 A-----EEAERWGLLKIS-------EDPLSDAEEMANRIS-NGPFQSYIAaKRMINLVLYNDLEEFLEYESAIQGYLGKT 227

                         170       180
                  ....*....|....*....|.
gi 2217377610 171 KDRLEGLLAFKEKRPPRYKGE 191
Cdd:PRK06072  228 EDFKEGISSFKEKREPKFKGI 248
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
14-188 1.85e-05

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 43.90  E-value: 1.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  14 RAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSAR 93
Cdd:PRK07827   91 TALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYLTGEK 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  94 vLDGKEAKAVGLIShvlEQNQEGDAAYRKALDLAREFLPQGPVAM-RVAKLAINQGMEVDLVTgLAIEEacyAQTIPTKD 172
Cdd:PRK07827  171 -FGAAEAARIGLVT---AAADDVDAAVAALLADLRRGSPQGLAESkALTTAAVLAGFDRDAEE-LTEES---ARLFVSDE 242

                         170
                  ....*....|....*.
gi 2217377610 173 RLEGLLAFKEKRPPRY 188
Cdd:PRK07827  243 AREGMTAFLQKRPPRW 258
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 24-145 4.39e-05

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 42.94  E-value: 4.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  24 PVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAI-IPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKA 102
Cdd:PLN03214  107 RLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQ 186

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2217377610 103 VGLISHVLEQNQEGDAAYRKaldlAREFLPQGPVAMRVAKLAI 145
Cdd:PLN03214  187 LGLIDEVVPAAALMEAAASA----MERALKLPSAARAATKALL 225
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
24-146 3.07e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 40.34  E-value: 3.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  24 PVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIpgGGGTQrLPRAIGMSLAKELIFSARVLDGKEAKAV 103
Cdd:PRK07938   94 AVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGAL--GAATH-LQRLVPQHLMRALFFTAATITAAELHHF 170

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2217377610 104 GLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAIN 146
Cdd:PRK07938  171 GSVEEVVPRDQLDEA----ALEVARKIAAKDTRVIRAAKEALN 209
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
26-151 7.42e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 39.25  E-value: 7.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  26 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGG------GTQRlpraigmslAKELIFSARVLDGKE 99
Cdd:PRK08272  129 PTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVWGVPATGmwayrlGPQR---------AKRLLFTGDCITGAQ 199

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2217377610 100 AKAVGLISHVLEQNQEGDAAYRKALDLAreFLPQGPVAMrvAKLAINQGMEV 151
Cdd:PRK08272  200 AAEWGLAVEAVPPEELDERTERLVERIA--AVPVNQLAM--VKLAVNSALLQ 247
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
26-180 3.77e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 37.08  E-value: 3.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217377610  26 PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGL 105
Cdd:PRK06023   99 PIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAEAAQEAGL 178

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217377610 106 ISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKlAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAF 180
Cdd:PRK06023  179 IWKIVDE----EAVEAETLKAAEELAAKPPQALQIAR-DLMRGPREDILARIDEEAKHFAARLKSAEARAAFEAF 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH