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Conserved domains on  [gi|2217268801|ref|XP_047280300|]
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enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X4 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
1-246 3.88e-94

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02600:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 251  Bit Score: 276.68  E-value: 3.88e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:PLN02600   10 LDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSLEALSI 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PLN02600   90 PTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGL 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:PLN02600  170 VNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKRK 245

                  ....*.
gi 2217268801 241 PKFVGK 246
Cdd:PLN02600  246 PVYTGK 251
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
1-246 3.88e-94

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 276.68  E-value: 3.88e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:PLN02600   10 LDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSLEALSI 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PLN02600   90 PTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGL 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:PLN02600  170 VNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKRK 245

                  ....*.
gi 2217268801 241 PKFVGK 246
Cdd:PLN02600  246 PVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
1-239 5.98e-77

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 232.75  E-value: 5.98e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMNDIAAFP 79
Cdd:COG1024    14 LNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFRALRRLP 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:COG1024    93 KPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAEEALELG 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 160 LVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKR 239
Cdd:COG1024   173 LVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLEKR 248
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
1-185 7.31e-60

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 187.38  E-value: 7.31e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA--EVGVFVQRLRGLMNDIAAF 78
Cdd:cd06558    14 LNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAgeEARAFIRELQELLRALLRL 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  79 PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 158
Cdd:cd06558    93 PKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISAEEALEL 172
                         170       180
                  ....*....|....*....|....*..
gi 2217268801 159 GLVNHAVaqneEGDAAYQRARALAQEI 185
Cdd:cd06558   173 GLVDEVV----PDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
1-246 3.00e-54

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 174.86  E-value: 3.00e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:pfam00378  11 LNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLLYTCPK 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:pfam00378  90 PVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGL 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:pfam00378 170 VDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEKRK 245

                  ....*.
gi 2217268801 241 PKFVGK 246
Cdd:pfam00378 246 PPWEDQ 251
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
1-243 1.06e-30

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 114.18  E-value: 1.06e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKER------EQMSEAEVGVF-VQRLrglmn 73
Cdd:TIGR01929  18 INRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRgdygyiDDSGVHRLNVLdVQRQ----- 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  74 dIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 153
Cdd:TIGR01929  93 -IRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQKKAREIWFLCRQYDAK 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 154 EAHVLGLVNHAVAQNEEGDAAYQraraLAQEILPQAPIAVRLGKVAIDrgTEVDIASG-MAIEGMCYAQNIPTRDRLEGM 232
Cdd:TIGR01929 172 QALDMGLVNTVVPLADLEKETVR----WCREILQKSPMAIRMLKAALN--ADCDGQAGlQELAGNATMLFYMTEEGQEGR 245
                         250
                  ....*....|.
gi 2217268801 233 AAFREKRTPKF 243
Cdd:TIGR01929 246 NAFLEKRQPDF 256
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
1-246 3.88e-94

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 276.68  E-value: 3.88e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:PLN02600   10 LDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSLEALSI 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PLN02600   90 PTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGL 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:PLN02600  170 VNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKRK 245

                  ....*.
gi 2217268801 241 PKFVGK 246
Cdd:PLN02600  246 PVYTGK 251
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
1-246 1.87e-93

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 275.07  E-value: 1.87e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:PRK07657   19 LNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTMEMVEQLPQ 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK07657   99 PVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEIGL 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:PRK07657  179 VEFVVPAHL----LEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTKDRLEGLQAFKEKRK 254

                  ....*.
gi 2217268801 241 PKFVGK 246
Cdd:PRK07657  255 PMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
1-239 5.98e-77

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 232.75  E-value: 5.98e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMNDIAAFP 79
Cdd:COG1024    14 LNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFRALRRLP 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:COG1024    93 KPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAEEALELG 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 160 LVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKR 239
Cdd:COG1024   173 LVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLEKR 248
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
1-246 3.58e-61

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 193.04  E-value: 3.58e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:PRK05809   19 INRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGLLGNKVFRKLENLDK 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK05809   99 PVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINAEEALRIGL 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEEGDAAYqrarALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:PRK05809  179 VNKVVEPEKLMEEAK----ALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGMTAFVEKRE 254

                  ....*.
gi 2217268801 241 PKFVGK 246
Cdd:PRK05809  255 KNFKNK 260
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
1-185 7.31e-60

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 187.38  E-value: 7.31e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA--EVGVFVQRLRGLMNDIAAF 78
Cdd:cd06558    14 LNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAgeEARAFIRELQELLRALLRL 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  79 PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 158
Cdd:cd06558    93 PKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISAEEALEL 172
                         170       180
                  ....*....|....*....|....*..
gi 2217268801 159 GLVNHAVaqneEGDAAYQRARALAQEI 185
Cdd:cd06558   173 GLVDEVV----PDEELLAAALELARRL 195
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
2-246 4.62e-56

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 179.83  E-value: 4.62e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   2 NRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQ-MSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:PRK07658   18 NHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIH-GEGRFFSAGADIKEFTSvTEAEQATELAQLGQVTFERVEKFSK 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK07658   96 PVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPITGAEALKWGL 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:PRK07658  176 VNGVFPEET----LLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEGVQAFLEKRK 251

                  ....*.
gi 2217268801 241 PKFVGK 246
Cdd:PRK07658  252 PSFSGK 257
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
1-246 1.20e-55

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 178.91  E-value: 1.20e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGVFVQRLRgLMNDIAAFPA 80
Cdd:PRK06688   20 INRPDKKNALTAAMYQALADALEAAATDPAVRVVVLT-GAGRAFSAGGDIKDFPKAPPKPPDELAPVNR-FLRAIAALPK 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK06688   98 PVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSAEEALRIGL 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAqNEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:PRK06688  178 VNRVVP-AAELDAE---ADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATAFIEKRK 253

                  ....*.
gi 2217268801 241 PKFVGK 246
Cdd:PRK06688  254 PDFTGF 259
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
1-246 1.41e-54

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 176.11  E-value: 1.41e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEreqMSEAE-VGVFVQRLRGLMNDIAAFP 79
Cdd:PRK09674   17 LNRPEARNALNNALLTQLVNELEAAATDTSIGVCVIT-GNARFFAAGADLNE---MAEKDlAATLNDPRPQLWQRLQAFN 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:PRK09674   93 KPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESITAQQAQQAG 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 160 LVNHaVAQNEegdAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKR 239
Cdd:PRK09674  173 LVSE-VFPPE---LTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGISAFLEKR 248

                  ....*..
gi 2217268801 240 TPKFVGK 246
Cdd:PRK09674  249 TPDFKGR 255
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
1-246 3.00e-54

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 174.86  E-value: 3.00e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:pfam00378  11 LNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLLYTCPK 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:pfam00378  90 PVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGL 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:pfam00378 170 VDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEKRK 245

                  ....*.
gi 2217268801 241 PKFVGK 246
Cdd:pfam00378 246 PPWEDQ 251
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
1-246 3.10e-50

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 164.84  E-value: 3.10e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEreqMSEAE-VGVFVQRLRGLMNDIAAFP 79
Cdd:PRK08138   23 LNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVL-TGGEKVFAAGADIKE---FATAGaIEMYLRHTERYWEAIAQCP 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:PRK08138   99 KPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALTGCMVPAPEALAIG 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 160 LVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKR 239
Cdd:PRK08138  179 LVSEVV----EDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQKEGMDAFLEKR 254

                  ....*..
gi 2217268801 240 TPKFVGK 246
Cdd:PRK08138  255 KPAYKGK 261
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
1-243 7.05e-48

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 158.67  E-value: 7.05e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVgvFVQRLRGLMNDIAAFPA 80
Cdd:PRK05862   19 LNRPKALNALNDALMDELGAALAAFDADEGIGAIVI-TGSEKAFAAGADIKEMADLSFMDV--YKGDYITNWEKVARIRK 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK05862   96 PVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERAGL 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEEGDAAYQRARALAQEILPqapiAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:PRK05862  176 VSRVVPADKLLDEALAAATTIASFSLP----AVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMAAFVEKRK 251

                  ...
gi 2217268801 241 PKF 243
Cdd:PRK05862  252 PVF 254
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
1-246 9.07e-47

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 155.97  E-value: 9.07e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEreQMSEAEVGVFVQRLRGLmNDIAAFPA 80
Cdd:PRK06494   19 LNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKE--QAAGGKRGWPESGFGGL-TSRFDLDK 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK06494   96 PIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREGLELGF 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQnEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQN--IPTRDRLEGMAAFREK 238
Cdd:PRK06494  176 VNEVVPA-GELLAA---AERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRDYPAVEarRASQDYIEGPKAFAEK 251

                  ....*...
gi 2217268801 239 RTPKFVGK 246
Cdd:PRK06494  252 RPPRWKGR 259
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
1-246 3.42e-43

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 146.67  E-value: 3.42e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVgvfvqRLRGLMNDIAAFPA 80
Cdd:PRK08252   18 INRPEARNAVNAAVAQGLAAALDELDADPDLSVGIL-TGAGGTFCAGMDLKAFARGERPSI-----PGRGFGGLTERPPR 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 -PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:PRK08252   92 kPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTAERAHELG 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 160 LVNHAVAQNEEGDAayqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKR 239
Cdd:PRK08252  172 LVNRLTEPGQALDA----ALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFTSADAKEGATAFAEKR 247

                  ....*..
gi 2217268801 240 TPKFVGK 246
Cdd:PRK08252  248 APVWTGK 254
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
1-241 4.17e-43

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 146.60  E-value: 4.17e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:PRK09076   18 LNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKAVAREMARRFGEAFEALSAFRG 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK09076   97 VSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAATALRIGL 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 240
Cdd:PRK09076  177 VEEVVEKGE----AREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNAFLEKRA 252

                  .
gi 2217268801 241 P 241
Cdd:PRK09076  253 P 253
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
1-245 4.40e-43

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 146.68  E-value: 4.40e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAEVGVFVQRLRGLMNDIAA 77
Cdd:PRK07511   18 LSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVL-TGAGGFFCAGGNLNrllENRAKPPSVQAASIDGLHDWIRAIRA 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  78 FPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 157
Cdd:PRK07511   97 FPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAERLHA 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 158 LGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 237
Cdd:PRK07511  177 LGVVNRLAEPGQALAEALALADQLAA----GSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGIAAFLE 252

                  ....*...
gi 2217268801 238 KRTPKFVG 245
Cdd:PRK07511  253 KRAPDYKR 260
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
2-246 8.45e-43

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 146.00  E-value: 8.45e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQM--SEAEVGVFVQRLRGLMNDIAAFP 79
Cdd:PRK06127   27 NNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESrsDAEAVAAYEQAVEAAQAALADYA 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:PRK06127  107 KPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDAAEALRIG 186
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 160 LVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDR----GTEVDIASGMAIEGMCYAqnipTRDRLEGMAAF 235
Cdd:PRK06127  187 LVHRVTAADDLETALADYAATIAG----NAPLTLRAAKRAIAEllkdEPERDMAACQALVAACFD----SEDYREGRAAF 258
                         250
                  ....*....|.
gi 2217268801 236 REKRTPKFVGK 246
Cdd:PRK06127  259 MEKRKPVFKGR 269
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
2-246 4.34e-41

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 141.28  E-value: 4.34e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGV-FVQRLRGLMNDIAAFPA 80
Cdd:PRK06144   24 NRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAVaYERRIDRVLGALEQLRV 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGL-IETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:PRK06144  104 PTIAAIAGACVGGGAAIAAACDLRIATPSARFGFpIARTLGNCLSMSNLARLVALLGAARVKDMLFTARLLEAEEALAAG 183
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 160 LVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAqnipTRDRLEGMAAFREKR 239
Cdd:PRK06144  184 LVNEVV----EDAALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDGDDLIRMCYM----SEDFREGVEAFLEKR 255

                  ....*..
gi 2217268801 240 TPKFVGK 246
Cdd:PRK06144  256 PPKWKGR 262
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
1-243 1.99e-40

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 139.51  E-value: 1.99e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGV----FVQRLRGLMNDIA 76
Cdd:PRK05980   18 LNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADValrdFVRRGQAMTARLE 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 156
Cdd:PRK05980   98 AFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELLLTGDAFSAERAL 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 157 VLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 236
Cdd:PRK05980  178 EIGLVNAVVPH----EELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAGSADLREGLAAWI 253

                  ....*..
gi 2217268801 237 EKRTPKF 243
Cdd:PRK05980  254 ERRRPAY 260
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
1-237 2.15e-40

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 139.34  E-value: 2.15e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVGVFvqRLRGLMNDIAAFPA 80
Cdd:PRK06190   19 LNRPEARNALSAALRRALFAALAEADADDDVDVVVL-TGADPAFCAGLDLKELGGDGSAYGAQD--ALPNPSPAWPAMRK 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK06190   96 PVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAADALRAGL 175
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217268801 161 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEgMCYAQNIPTRDRLEGMAAFRE 237
Cdd:PRK06190  176 VTEVVPHDE----LLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALE-AEAARAHNRSVSPDGIAARRE 247
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
2-244 2.83e-40

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 139.25  E-value: 2.83e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   2 NRPSARNALGNVFVSELLETLAQLREDRQVR-VLLfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAF-- 78
Cdd:PRK07509   19 NRPDKMNALDFAMFEELIATIKRLKKDRGIRaVIL--SGEGGAFCAGLDVKSVASSPGNAVKLLFKRLPGNANLAQRVsl 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  79 -----PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 153
Cdd:PRK07509   97 gwrrlPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELTYTARVFSAE 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 154 EAHVLGLVNHAVaqneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 233
Cdd:PRK07509  177 EALELGLVTHVS------DDPLAAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARESVEQIRLLLGKNQKIAVK 250
                         250
                  ....*....|.
gi 2217268801 234 AFREKRTPKFV 244
Cdd:PRK07509  251 AQMKKRAPKFL 261
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
8-180 9.85e-40

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 145.42  E-value: 9.85e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   8 NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQM-SEAEVGVFVQRLRGLMNDIAAFPAPTIAAM 86
Cdd:PRK11154   29 NTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINMLAACkTAQEAEALARQGQQLFAEIEALPIPVVAAI 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  87 DGFALGGGLELALACDLRVAASSA--VMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHA 164
Cdd:PRK11154  109 HGACLGGGLELALACHYRVCTDDPktVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLRAKQALKLGLVDDV 188
                         170
                  ....*....|....*.
gi 2217268801 165 VAQNEEGDAAYQRARA 180
Cdd:PRK11154  189 VPHSILLEVAVELAKK 204
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
1-246 1.34e-38

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 134.82  E-value: 1.34e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKERE--QMSEAEVGV--F--VQRLRGLMNd 74
Cdd:PRK03580   18 LDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAegEAPDADFGPggFagLTEIFDLDK- 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  75 iaafpaPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTE 154
Cdd:PRK03580   96 ------PVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEE 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 155 AHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP----TRDRLE 230
Cdd:PRK03580  170 ALRWGIVNRVVPQAELMD----RARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRSGVLKHYPsvlhSEDALE 245
                         250
                  ....*....|....*.
gi 2217268801 231 GMAAFREKRTPKFVGK 246
Cdd:PRK03580  246 GPRAFAEKRDPVWKGR 261
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
1-246 1.92e-37

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 132.15  E-value: 1.92e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEvgvfvqRLRGLMNDIAAFPA 80
Cdd:PRK07799   20 MNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKAATKKPPGD------SFKDGSYDPSRIDA 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 ---------PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 151
Cdd:PRK07799   93 llkgrrltkPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHIT 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 152 GTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 231
Cdd:PRK07799  173 AAEAKEIGLIGHVVPD----GQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEG 248
                         250
                  ....*....|....*
gi 2217268801 232 MAAFREKRTPKFVGK 246
Cdd:PRK07799  249 PRAFAEKRAPNFQGR 263
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
1-245 3.59e-37

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 131.63  E-value: 3.59e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADL-----------KEREQMSEAEVGVFVQRLR 69
Cdd:PRK06142   21 LNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKH-FSYGIDLpamagvfgqlgKDGLARPRTDLRREILRLQ 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  70 GLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 149
Cdd:PRK06142  100 AAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGHLRELALTGRD 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 150 LSGTEAHVLGLVNHAVaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRL 229
Cdd:PRK06142  180 IDAAEAEKIGLVNRVY---DDADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAAMLPSKDLT 256
                         250
                  ....*....|....*.
gi 2217268801 230 EGMAAFREKRTPKFVG 245
Cdd:PRK06142  257 EAIAAHMEKRPPEFTG 272
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
1-246 4.72e-37

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 130.86  E-value: 4.72e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNAL-GNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFP 79
Cdd:PRK09245   18 MNRPETRNALsDNDAVDALVAACAAINADRSVRAVIL-TGAGTAFSSGGNVKDMRARVGAFGGSPADIRQGYRHGIQRIP 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 A-------PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 152
Cdd:PRK09245   97 LalynlevPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFTGDAIDA 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 153 TEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 232
Cdd:PRK09245  177 ATALEWGLVSRVVPA----DQLLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAYQALAHHTADHREAV 252
                         250
                  ....*....|....
gi 2217268801 233 AAFREKRTPKFVGK 246
Cdd:PRK09245  253 DAFLEKRPPVFTGR 266
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
1-246 4.71e-36

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 128.22  E-value: 4.71e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRqVRVLLFRSGVKG-VFCAGADLKEREQMSEAEVGvFVQRLRGLMNDIAAFP 79
Cdd:PRK11423   19 FNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkVWSAGHDIHELPSGGRDPLS-YDDPLRQILRMIQKFP 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:PRK11423   97 KPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQRALAVG 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 160 LVNHaVAQNEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEvdiASGMAIEGMCYAQNI-----PTRDRLEGMAA 234
Cdd:PRK11423  177 ILNH-VVEVEELEDF---TLQMAHHISEKAPLAIAVIKEQLRVLGE---AHPMNPDEFERIQGLrravyDSEDYQEGMNA 249
                         250
                  ....*....|..
gi 2217268801 235 FREKRTPKFVGK 246
Cdd:PRK11423  250 FLEKRKPVFVGH 261
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
1-246 4.93e-35

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 125.58  E-value: 4.93e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEvGVFVQRLR---GLMNDIAA 77
Cdd:PRK06495   19 LDNPPV-NALSRELRDELIAVFDEISERPDVRVVVL-TGAGKVFCAGADLKGRPDVIKGP-GDLRAHNRrtrECFHAIRE 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  78 FPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLlpgAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 157
Cdd:PRK06495   96 CAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHSLTRRMMLTGYRVPAAELYR 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 158 LGLVNHAVAqneeGDAAYQRARALAQEILPQAPIAVRLGKVAIdrgtevDIASGMAI-EGMCYAQNIP-----TRDRLEG 231
Cdd:PRK06495  173 RGVIEACLP----PEELMPEAMEIAREIASKSPLATRLAKDAL------NTIENMSLrDGYRYEQDITaklakTEDAKEA 242
                         250
                  ....*....|....*
gi 2217268801 232 MAAFREKRTPKFVGK 246
Cdd:PRK06495  243 QRAFLEKRPPVFKGR 257
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
2-174 5.33e-35

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 131.91  E-value: 5.33e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKERE---QMSEAEVGVFVQRLRGLMNDIAAF 78
Cdd:PRK11730   23 DAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSA-KDAFIVGADITEFLslfAAPEEELSQWLHFANSIFNRLEDL 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  79 PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 158
Cdd:PRK11730  102 PVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKV 181
                         170
                  ....*....|....*.
gi 2217268801 159 GLVNHAVAQNEEGDAA 174
Cdd:PRK11730  182 GAVDAVVAPEKLQEAA 197
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
8-239 5.95e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 125.15  E-value: 5.95e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   8 NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMD 87
Cdd:PRK06143   29 NILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISRLRDLCDAVRHFPVPVIARIP 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  88 GFALGGGLELALACDLRVAASSAVMGLIETTRGlLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVnHAVAQ 167
Cdd:PRK06143  109 GWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTGETIDAAQALAWGLV-DRVVP 186
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217268801 168 NEEGDAAYQRaraLAQEILPQAPIAVRLGKVAI----DRGTEVDIASGMAIEGMCYAQNIPTRDrlegMAAFREKR 239
Cdd:PRK06143  187 LAELDAAVER---LAASLAGCGPQALRQQKRLLreweDMPLDVAIDDSVAEFGAAFLTGEPQRH----MAAFLNRK 255
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
1-242 1.60e-34

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 124.36  E-value: 1.60e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPA 80
Cdd:PRK08150   17 LNRPAKRNALNDGLIAALRAAFARLPEGVRAVVL---HGEGDHFCAGLDLSELRERDAGEGMHHSRRWHRVFDKIQYGRV 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK08150   94 PVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDAQEGERLGL 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMC--YAQNIP-TRDRLegmAAFRE 237
Cdd:PRK08150  174 AQYLVPAGE----ALDKAMELARRIAQNAPLTNFAVLNALPRIADMSADDGLFVESLMaaVAQSAPeAKERL---RAFLE 246

                  ....*
gi 2217268801 238 KRTPK 242
Cdd:PRK08150  247 KKAAK 251
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
1-243 8.23e-34

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 123.09  E-value: 8.23e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE----REQMSEAEVGVFVQRLR----GLM 72
Cdd:PLN02664   23 LNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIIL-SGAGDHFCSGIDLKTlnsiSEQSSSGDRGRSGERLRrkikFLQ 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  73 NDIAAFP---APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 149
Cdd:PLN02664  102 DAITAIEqcrKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELALTGRR 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 150 LSGTEAHVLGLVNHAVAQNEEGDaayQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRL 229
Cdd:PLN02664  182 FSGSEAKELGLVSRVFGSKEDLD---EGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNSAMLVSDDLN 258
                         250
                  ....*....|....
gi 2217268801 230 EGMAAFREKRTPKF 243
Cdd:PLN02664  259 EAVSAQIQKRKPVF 272
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
1-246 1.09e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 122.34  E-value: 1.09e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQM---SEAEVGVFVQRLRGLMNDIAA 77
Cdd:PRK05995   19 LNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVL-AGAGKAFCAGADLNWMKKMagySDDENRADARRLADMLRAIYR 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  78 FPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPgaggTQRLP---RCLGVALAKELIFTGRRLSGTE 154
Cdd:PRK05995   98 CPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGERAARRYFLTAERFDAAE 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 155 AHVLGLVNHAVAQnEEGDAAYQrarALAQEILPQAPIAVRLGKVAIDrgtevDIAsGMAIEGMCYAQnipTRDRL----- 229
Cdd:PRK05995  174 ALRLGLVHEVVPA-EALDAKVD---ELLAALVANSPQAVRAGKRLVR-----DVA-GRPIDAALIAD---TASRIalira 240
                         250       260
                  ....*....|....*....|..
gi 2217268801 230 -----EGMAAFREKRTPKFVGK 246
Cdd:PRK05995  241 teearEGVAAFLEKRKPAWRGR 262
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
1-241 1.24e-32

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 119.66  E-value: 1.24e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEreqMSEAEVGVFVQRLRG----LMNDIA 76
Cdd:PRK08139   26 LNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLKE---MRAARGLAYFRALFArcsrVMQAIV 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLL---PGAGgtqrLPRCLGVALAKELIFTGRRLSGT 153
Cdd:PRK08139  102 ALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVA----LSRNVPRKQAMEMLLTGEFIDAA 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 154 EAHVLGLVNHAVAQNEEGDAAyqraRALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 233
Cdd:PRK08139  178 TAREWGLVNRVVPADALDAAV----ARLAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMMAEDAEEGID 253

                  ....*...
gi 2217268801 234 AFREKRTP 241
Cdd:PRK08139  254 AFLEKRPP 261
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
1-246 9.09e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 117.50  E-value: 9.09e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSE------AEVGVFVQRLRGLMND 74
Cdd:PRK06210   21 LNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRG-FCAGADMGELQTIDPsdgrrdTDVRPFVGNRRPDYQT 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  75 IAAF----PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 150
Cdd:PRK06210  100 RYHFltalRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANALDLLLSARTF 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 151 SGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPqAPIAVRLGKVAIDRGTEVDIASGMAIEGMcyAQNIPTRDRLE 230
Cdd:PRK06210  180 YAEEALRLGLVNRVVPPDELMERTLAYAEDLARNVSP-ASMAVIKRQLYEDAFQTLAEATARANREM--HESLQRPDFIE 256
                         250
                  ....*....|....*.
gi 2217268801 231 GMAAFREKRTPKFVGK 246
Cdd:PRK06210  257 GVASFLEKRPPRFPGL 272
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
1-242 1.04e-31

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 117.42  E-value: 1.04e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE--REQMSEAEVGV---------FVQRLR 69
Cdd:PRK09120   23 LNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLT-GAGDAWSAGMDLKEyfRETDAQPEILQerirreaygWWRRLR 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  70 glmndiaAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 149
Cdd:PRK09120  102 -------WYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMTGET 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 150 LSGTEAHVLGLVNHAV--AQNEEgdaayqRARALAQEILPQAPIAVRLGKVAIDRGTEvdiasgmaiegMCYAQNI---- 223
Cdd:PRK09120  175 FTGRKAAEMGLVNESVplAQLRA------RTRELAAKLLEKNPVVLRAAKDGFKRVRE-----------LTWDQAEdyly 237
                         250       260
                  ....*....|....*....|....*....
gi 2217268801 224 ----------PTRDRLEGMAAFREKRTPK 242
Cdd:PRK09120  238 akleqansldPEGGREEGLKQFLDDKSYK 266
PLN02888 PLN02888
enoyl-CoA hydratase
1-242 1.81e-31

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 116.39  E-value: 1.81e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMseaevgvfvqrLRGLMNDIAAFPA 80
Cdd:PLN02888   25 INRPKALNALTRPMMVELAAAFKRLDEDDSVKVIIL-TGSGRAFCSGVDLTAAEEV-----------FKGDVKDVETDPV 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 --------PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 152
Cdd:PLN02888   93 aqmercrkPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTA 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 153 TEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIE---GMCYAQNIpTRDRL 229
Cdd:PLN02888  173 ETAERWGLVNHVVEESE----LLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEkerAHDYYNGM-TKEQF 247
                         250
                  ....*....|...
gi 2217268801 230 EGMAAFREKRTPK 242
Cdd:PLN02888  248 QKMQEFIAGRSSK 260
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
1-243 1.06e-30

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 114.18  E-value: 1.06e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKER------EQMSEAEVGVF-VQRLrglmn 73
Cdd:TIGR01929  18 INRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRgdygyiDDSGVHRLNVLdVQRQ----- 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  74 dIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 153
Cdd:TIGR01929  93 -IRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQKKAREIWFLCRQYDAK 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 154 EAHVLGLVNHAVAQNEEGDAAYQraraLAQEILPQAPIAVRLGKVAIDrgTEVDIASG-MAIEGMCYAQNIPTRDRLEGM 232
Cdd:TIGR01929 172 QALDMGLVNTVVPLADLEKETVR----WCREILQKSPMAIRMLKAALN--ADCDGQAGlQELAGNATMLFYMTEEGQEGR 245
                         250
                  ....*....|.
gi 2217268801 233 AAFREKRTPKF 243
Cdd:TIGR01929 246 NAFLEKRQPDF 256
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
1-201 4.01e-29

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 109.16  E-value: 4.01e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSArNALGNVFVSELLETLAQL-REDRQVRVLLFrsGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFP 79
Cdd:PRK05869   23 LSRPPT-NALTRQVYREIVAAANELgRRDDVAAVILY--GGHEIFSAGDDMPELRTLSAQEADTAARVRQQAVDAVAAIP 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:PRK05869  100 KPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALG 179
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2217268801 160 LVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAID 201
Cdd:PRK05869  180 LIDEMVAP----DDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
1-189 4.96e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 109.60  E-value: 4.96e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE--REQMSEAEVG----VFVQRLRglmnd 74
Cdd:PRK08259   18 LNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVL-WGAGGTFCAGADLKAvgTGRGNRLHPSgdgpMGPSRMR----- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  75 iaaFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMG---------LIEttrgllpgaGGTQRLPRCLGVALAKELIF 145
Cdd:PRK08259   92 ---LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGvfcrrwgvpLID---------GGTVRLPRLIGHSRAMDLIL 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2217268801 146 TGRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEI--LPQA 189
Cdd:PRK08259  160 TGRPVDADEALAIGLANRVVPKGQ----ARAAAEELAAELaaFPQT 201
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-246 7.05e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 109.62  E-value: 7.05e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAE---VGVFVQRLRG-LMNDIA 76
Cdd:PRK08140   19 LNRPDKLNSFTREMHRELREALDQV-EDDGARALLLTGAGRG-FCAGQDLADRDVTPGGAmpdLGESIETFYNpLVRRLR 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 156
Cdd:PRK08140   97 ALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLALLGEKLSAEQAE 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 157 VLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 236
Cdd:PRK08140  177 QWGLIWRVVDDAALADEAQQLAAHLAT----QPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADYAEGVSAFL 252
                         250
                  ....*....|
gi 2217268801 237 EKRTPKFVGK 246
Cdd:PRK08140  253 EKRAPRFTGR 262
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
1-202 7.63e-28

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 111.47  E-value: 7.63e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK--EREQMSEaEVGVFVQRLRGLMNDIAA 77
Cdd:TIGR02441  28 IDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQmiAACKTAQ-EVTQLSQEGQEMFERIEK 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  78 FPAPTIAAMDGFALGGGLELALACDLRVAA--SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEA 155
Cdd:TIGR02441 107 SQKPIVAAISGSCLGGGLELALACHYRIATkdRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRA 186
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2217268801 156 HVLGLVNHAVAQNEEG-DAAYQRARALAQEILPQAPIAVRLGKVAIDR 202
Cdd:TIGR02441 187 KKMGIVDQLVDPLGPGlKPAEENTIEYLEEVAVKFAQGLANGKLSINR 234
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
1-246 1.64e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 106.63  E-value: 1.64e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADL-------------KEREQMSEAEVGVFVQR 67
Cdd:PRK08260   19 LNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIV-TGAGRAFCAGADLsaggntfdldaprTPVEADEEDRADPSDDG 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  68 LRG----LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKEL 143
Cdd:PRK08260   98 VRDgggrVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVGLQTALEW 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 144 IFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEilpQAPIAVRLGKVAIDRGTEVDI-ASGMAIEGMCYAQN 222
Cdd:PRK08260  178 VYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADN---TSPVSVALTRQMMWRMAGADHpMEAHRVDSRAIYSR 254
                         250       260
                  ....*....|....*....|....
gi 2217268801 223 IPTRDRLEGMAAFREKRTPKFVGK 246
Cdd:PRK08260  255 GRSGDGKEGVSSFLEKRPAVFPGK 278
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
1-245 9.90e-27

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 104.28  E-value: 9.90e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE----REQMSEAEVGVFVQRLRGLMNDIA 76
Cdd:PRK08258   32 LNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLT-GAGGNFCSGGDVHEiigpLTKMDMPELLAFTRMTGDLVKAMR 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGlLPGA--GGTQRLPRCLGVALAKELIFTGRRLSGTE 154
Cdd:PRK08258  111 ACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVG-LAGAdmGACALLPRIIGQGRASELLYTGRSMSAEE 189
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 155 AHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRgtEVDIASGMAIEGMCYAQNI--PTRDRLEGM 232
Cdd:PRK08258  190 GERWGFFNRLV----EPEELLAEAQALARRLAAGPTFAHGMTKTMLHQ--EWDMGLEEAIEAEAQAQAIcmQTEDFRRAY 263
                         250
                  ....*....|...
gi 2217268801 233 AAFREKRTPKFVG 245
Cdd:PRK08258  264 EAFVAKRKPVFEG 276
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
1-246 1.06e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 103.50  E-value: 1.06e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRV-LLFRSGvkGVFCAGADLKE--------REQMSEAEVGVF--VQRLR 69
Cdd:PRK06563   14 LDRPAKRNAFDSAMLDDLALALGEYEADDELRVaVLFAHG--EHFTAGLDLADvapklaagGFPFPEGGIDPWgtVGRRL 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  70 GlmndiaafpAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 149
Cdd:PRK06563   92 S---------KPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDE 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 150 LSGTEAHVLGLVNHAVAQNEEgdaaYQRARALAQEILPQAPIAVRL----GKVAIDRGTEVDIASGMAIegmcYAQNIPT 225
Cdd:PRK06563  163 FDAQEALRLGLVQEVVPPGEQ----LERAIELAERIARAAPLGVQAtlasARAAVREGEAAAAAQLPPE----LRPLFTS 234
                         250       260
                  ....*....|....*....|.
gi 2217268801 226 RDRLEGMAAFREKRTPKFVGK 246
Cdd:PRK06563  235 EDAKEGVQAFLERRPARFKGR 255
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
1-246 3.19e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 99.72  E-value: 3.19e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKEreQMSEAEVGVFvQRLRGLMNDIA---- 76
Cdd:PRK07659   21 LNRPEALNALDEPMLKELLQALKEV-AESSAHIVVLRGNGRG-FSAGGDIKM--MLSSNDESKF-DGVMNTISEIVvtly 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 156
Cdd:PRK07659   96 TMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSATEAL 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 157 VLGLVNhAVAQNEEGDAAYQRARALAQEILpQAPIAVRLGKVAIDRGTEVDIasgMAIEGMCYAQNIPTRDRLEGMAAFR 236
Cdd:PRK07659  176 DLGLID-EVIGGDFQTAAKQKISEWLQKPL-KAMIETKQIYCELNRSQLEQV---LQLEKRAQYAMRQTADHKEGIRAFL 250
                         250
                  ....*....|
gi 2217268801 237 EKRTPKFVGK 246
Cdd:PRK07659  251 EKRLPVFKGE 260
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
1-246 5.15e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 98.94  E-value: 5.15e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRsGVKGVFCAGADLKEREQMSEaevgvFVQRLRGLMNDIAAFPA 80
Cdd:PRK07854   15 LQRPERRNALNAELCEELREAVRKA-VDESARAIVLT-GQGTVFCAGADLSGDVYADD-----FPDALIEMLHAIDAAPV 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK07854   88 PVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAMLLGAEKLTAEQALATGM 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 161 VnhavaqNEEGDAAyqRARALAQEILPQAPIAVRLGKVAI-DRGTEVDIASGmaiEGMCYAQNIPTRDRLEGMAAFREKR 239
Cdd:PRK07854  168 A------NRIGTLA--DAQAWAAEIAGLAPLALQHAKRVLnDDGAIEEAWPA---HKELFDKAWASQDAIEAQVARIEKR 236

                  ....*..
gi 2217268801 240 TPKFVGK 246
Cdd:PRK07854  237 PPKFQGA 243
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
1-246 8.96e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 98.59  E-value: 8.96e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-EREQM--SEAEVGVFVQRLRGLMNDIAA 77
Cdd:PRK07468   20 LNRPEKHNALSARMIAELTTAARRLAADAAVRVVVL-TGAGKSFCAGGDLGwMRAQMtaDRATRIEEARRLAMMLKALND 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  78 FPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRcLGVALAKELIFTGRRLSGTEAHV 157
Cdd:PRK07468   99 LPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFMSARLFDAEEAVR 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 158 LGLVNHAVAQnEEGDAAYQRARAlaqEILPQAPIAV-RLGKVAIDRGTEVDIAS-GMAIEGMcyAQNIPTRDRLEGMAAF 235
Cdd:PRK07468  178 LGLLSRVVPA-ERLDAAVEAEVT---PYLSCAPGAVaAAKALVRALGAPIDEAViDATIEAL--ADTWETEEAREGIAAF 251
                         250
                  ....*....|.
gi 2217268801 236 REKRTPKFVGK 246
Cdd:PRK07468  252 FDKRAPAWRGG 262
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
2-165 1.22e-24

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 99.85  E-value: 1.22e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-REQMSE---AEVGVFVQRLRGLMNDIA 76
Cdd:pfam16113   7 NRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGaGERA-FCAGGDVRAlYEAAKAgggEAGRDFFREEYRLNYLIA 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRC---LGVALAkeliFTGRRLSGT 153
Cdd:pfam16113  86 TYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLpgeLGLYLA----LTGARLNGA 161
                         170
                  ....*....|..
gi 2217268801 154 EAHVLGLVNHAV 165
Cdd:pfam16113 162 DALAAGLATHYV 173
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
1-243 2.31e-24

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 97.66  E-value: 2.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ---MSEAEVGVF----VQRLrglmn 73
Cdd:PRK07396   28 INRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYggyVDDDGVPRLnvldLQRL----- 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  74 dIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 153
Cdd:PRK07396  103 -IRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCRQYDAQ 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 154 EAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDrgTEVDIASGMA-IEG---MCYAQnipTRDRL 229
Cdd:PRK07396  182 EALDMGLVNTVVPLADLEKETVRWCR----EMLQNSPMALRCLKAALN--ADCDGQAGLQeLAGnatMLFYM---TEEAQ 252
                         250
                  ....*....|....
gi 2217268801 230 EGMAAFREKRTPKF 243
Cdd:PRK07396  253 EGRNAFNEKRQPDF 266
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
1-183 5.35e-23

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 93.49  E-value: 5.35e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDiaaFPA 80
Cdd:PRK07110   20 MQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILT-GYPNYFATGGTQEGLLSLQTGKGTFTEANLYSLALN---CPI 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK07110   96 PVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLLTARYYRGAELKKRGV 175
                         170       180
                  ....*....|....*....|...
gi 2217268801 161 VNHAVAQNEEGDAAYQRARALAQ 183
Cdd:PRK07110  176 PFPVLPRAEVLEKALELARSLAE 198
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
1-242 8.38e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 93.87  E-value: 8.38e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEVGvFVQRLRGLMNDIAAF-- 78
Cdd:PRK08290   19 LNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKH-FSAGHDLGSGTPGRDRDPG-PDQHPTLWWDGATKPgv 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  79 ---------------------PAPTIAAMDGFALGGGLELALACDLRVAASSAV-------MgliettrgllpGAGGTQR 130
Cdd:PRK08290   97 eqryarewevylgmcrrwrdlPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFfsdpvvrM-----------GIPGVEY 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 131 L--PRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVD- 207
Cdd:PRK08290  166 FahPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDE----LEAETLELARRIAAMPPFGLRLTKRAVNQTLDAQg 241
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2217268801 208 ----IASGMAIEGMCYAQN------IPTRDRLEGMAAFREKRTPK 242
Cdd:PRK08290  242 fraaLDAVFDLHQLGHAHNaevggdRLGGADARGMADARKAAAAK 286
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
1-243 1.43e-22

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 92.78  E-value: 1.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA-EVGVFVQR-LRGLMNDIAAF 78
Cdd:PRK07327   27 LNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIR-GEGKAFSAGGDLALVEEMADDfEVRARVWReARDLVYNVINC 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  79 PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 158
Cdd:PRK07327  106 DKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLLLCEPVSGEEAERI 185
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 159 GLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAID---RGTEVDIASGMAIEGMCYAqnipTRDRLEGMAAF 235
Cdd:PRK07327  186 GLVSLAVDDDELLPKALEVAERLAA----GSQTAIRWTKYALNnwlRMAGPTFDTSLALEFMGFS----GPDVREGLASL 257

                  ....*...
gi 2217268801 236 REKRTPKF 243
Cdd:PRK07327  258 REKRAPDF 265
PLN02921 PLN02921
naphthoate synthase
1-243 4.18e-22

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 92.93  E-value: 4.18e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFvQRLR--GLMNDIAAF 78
Cdd:PLN02921   82 INRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKDGYVGPDDA-GRLNvlDLQIQIRRL 160
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  79 PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 158
Cdd:PLN02921  161 PKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYTASEALKM 240
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 159 GLVNHAV--AQNEEGDAAYQRaralaqEILPQAPIAVRLGKVAIDRGTevDIASGmaIEGMcyAQNIP-----TRDRLEG 231
Cdd:PLN02921  241 GLVNTVVplDELEGETVKWCR------EILRNSPTAIRVLKSALNAAD--DGHAG--LQEL--GGNATllfygSEEGNEG 308
                         250
                  ....*....|..
gi 2217268801 232 MAAFREKRTPKF 243
Cdd:PLN02921  309 RTAYLEGRAPDF 320
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
1-243 4.23e-22

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 91.80  E-value: 4.23e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLF-----RSGVKGVFCAGADLKEREQ---MSEAEVGVF----VQRL 68
Cdd:COG0447    33 INRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLtgngpSKDGGWAFCSGGDQRVRGRggyVYEDGVGRLnileVQRL 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  69 rglmndIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 148
Cdd:COG0447   113 ------IRFMPKPVIAMVAGWAIGGGHVLHVVCDLTIASENARFGQTGPDVGSFDAGYGSAYLARQVGQKKAREIWFLCR 186
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 149 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDRGTEvdiasGMAieG----------MC 218
Cdd:COG0447   187 QYSAQEALEMGLVNKVVPHAELEEEAVEWAR----EILEKSPTAIRMLKAAFNADDD-----GLA--GqqefageatrLA 255
                         250       260
                  ....*....|....*....|....*
gi 2217268801 219 YAqnipTRDRLEGMAAFREKRTPKF 243
Cdd:COG0447   256 YM----TDEAQEGRDAFLEKRKPDF 276
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
8-200 1.12e-20

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 87.33  E-value: 1.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   8 NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEVGVFVQRlrglmNDIAAF------PAP 81
Cdd:PRK07938   23 NALPSAGWFALADAITAAGADPDTRVVVLRAEGRG-FNAGVDIKELQATPGFTALIDANR-----GCFAAFravyecAVP 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  82 TIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLprcLGVALAKELIFTGRRLSGTEAHVLGLV 161
Cdd:PRK07938   97 VIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGALGAATHLQRL---VPQHLMRALFFTAATITAAELHHFGSV 173
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2217268801 162 nHAVAQNEEGDAAyqrARALAQEILPQAPIAVRLGKVAI 200
Cdd:PRK07938  174 -EEVVPRDQLDEA---ALEVARKIAAKDTRVIRAAKEAL 208
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
1-244 1.14e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 87.97  E-value: 1.14e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAE---VGVFVQRLRGLMNDIA- 76
Cdd:PRK05864   25 LNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG-FSSGADHKSAGVVPHVEgltRPTYALRSMELLDDVIl 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 ---AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGA-GGTQRLPRCLGVALAKELIFTGRRLSG 152
Cdd:PRK05864  104 alrRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASElGLSYLLPRAIGSSRAFEIMLTGRDVDA 183
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 153 TEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTevdIASGMAIEGMcyAQ---NIPTRDRL 229
Cdd:PRK05864  184 EEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSGLDAAS---LEAHMQAEGL--GQlfvRLLTANFE 258
                         250
                  ....*....|....*
gi 2217268801 230 EGMAAFREKRTPKFV 244
Cdd:PRK05864  259 EAVAARAEKRPPVFT 273
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
1-246 4.41e-20

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 86.33  E-value: 4.41e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDR-QVRVLLFRSGVKGvFCAGADLKER-EQMSEAEVGV------------FVQ 66
Cdd:PRK05981   19 LDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAGRG-FCTGANLQGRgSGGRESDSGGdagaaletayhpFLR 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  67 RLRGlmndiaaFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFT 146
Cdd:PRK05981   98 RLRN-------LPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELSLL 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 147 GRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAqeilpQAPiAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP-- 224
Cdd:PRK05981  171 GEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELA-----NGP-TVALGLIRKLYWDSPENDFEEQLNLEREAQRIAgk 244
                         250       260
                  ....*....|....*....|..
gi 2217268801 225 TRDRLEGMAAFREKRTPKFVGK 246
Cdd:PRK05981  245 TEDFKEGVGAFLQKRPAQFKGR 266
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
1-245 8.39e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 85.22  E-value: 8.39e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMNDIAAFp 79
Cdd:PRK06072   15 MSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIV-TGEGRAFCVGADLSEfAPDFAIDLRETFYPIIREIRFSDKIY- 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 aptIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRcLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:PRK06072   93 ---ISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLK-LTGQRFYEILVLGGEFTAEEAERWG 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 160 LVnhavaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKR 239
Cdd:PRK06072  169 LL-------KISEDPLSDAEEMANRISNGPFQSYIAAKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFKEGISSFKEKR 241

                  ....*.
gi 2217268801 240 TPKFVG 245
Cdd:PRK06072  242 EPKFKG 247
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
2-169 1.14e-19

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 86.03  E-value: 1.14e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-----REQMSEAEVGVFVQRLRgLMNDI 75
Cdd:PRK05617   19 NRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGaGERG-FCAGGDIRAlyeaaRAGDPLAADRFFREEYR-LNALI 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  76 AAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGvALAKELIFTGRRLSGTEA 155
Cdd:PRK05617   97 ARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPG-ALGTYLALTGARISAADA 175
                         170
                  ....*....|....
gi 2217268801 156 HVLGLVNHAVAQNE 169
Cdd:PRK05617  176 LYAGLADHFVPSAD 189
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
1-182 1.26e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 84.78  E-value: 1.26e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEreqMSEAEVGVFVQRLRGLMN---DIAA 77
Cdd:PRK05870   18 VNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVV-TGAGKAFCAGADLTA---LGAAPGRPAEDGLRRIYDgflAVAS 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  78 FPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 157
Cdd:PRK05870   94 CPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAEAAVR 173
                         170       180
                  ....*....|....*....|....*
gi 2217268801 158 LGLVNHAVaqNEEGDAAYQRARALA 182
Cdd:PRK05870  174 HGLALMVA--DDPVAAALELAAGPA 196
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
1-245 1.55e-19

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 84.73  E-value: 1.55e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLFRSGvkGVFCAGADLKE--REQMSEAEVGVFVQR-LRGLMNDIA 76
Cdd:PRK07827   21 LDSPHNRNALSARLVAQLHDGLRAAAADPAVRaVVLTHTG--GTFCAGADLSEagGGGGDPYDAAVARAReMTALLRAIV 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIfTGRRLSGTEAH 156
Cdd:PRK07827   99 ELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYL-TGEKFGAAEAA 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 157 VLGLVNHAVAQNEEGDAayqrarALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 236
Cdd:PRK07827  178 RIGLVTAAADDVDAAVA------ALLADLRRGSPQGLAESKALTTAAVLAGFDRDAEELTEESARLFVSDEAREGMTAFL 251

                  ....*....
gi 2217268801 237 EKRTPKFVG 245
Cdd:PRK07827  252 QKRPPRWAL 260
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
1-241 1.99e-19

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 84.47  E-value: 1.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGVFV---QRLRGLMNDIAA 77
Cdd:PRK05674   21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLR-GRGRHFSAGADLAWMQQSADLDYNTNLddaRELAELMYNLYR 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  78 FPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPgAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 157
Cdd:PRK05674  100 LKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAP-AVISPFVVKAIGERAARRYALTAERFDGRRARE 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 158 LGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKvaiDRGTEVDiASGMAIEGMCYAQNIPTRDRL-----EGM 232
Cdd:PRK05674  179 LGLLAESYPAAE----LEAQVEAWIANLLLNSPQALRASK---DLLREVG-DGELSPALRRYCENAIARIRVsaegqEGL 250

                  ....*....
gi 2217268801 233 AAFREKRTP 241
Cdd:PRK05674  251 RAFLEKRTP 259
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
2-243 6.50e-17

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 78.14  E-value: 6.50e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFR----SGVKG--VFCAGADLKER-------------EQMSEAEVG 62
Cdd:PRK08321   41 DRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTgngpSPKDGgwAFCSGGDQRIRgrdgyqyaegdeaDTVDPARAG 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  63 VF----VQRLrglmndIAAFPAPTIAAMDGFALGGGLELALACDLRVAASS-AVMGLIETTRGLLPGAGGTQRLPRCLGV 137
Cdd:PRK08321  121 RLhileVQRL------IRFMPKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGSAYLARQVGQ 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801 138 ALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVA---IDRG-TEVDIASGMA 213
Cdd:PRK08321  195 KFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAR----EINGKSPTAMRMLKYAfnlTDDGlVGQQLFAGEA 270
                         250       260       270
                  ....*....|....*....|....*....|
gi 2217268801 214 IEgMCYAqnipTRDRLEGMAAFREKRTPKF 243
Cdd:PRK08321  271 TR-LAYM----TDEAQEGRDAFLEKRDPDW 295
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
30-174 2.09e-16

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 76.49  E-value: 2.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  30 QVRVLLFRSGVKGVFCAGADL---------KEREQMSE-AEVGVfvqrlRGLMNDIAAF--PAPTIAAMDGFALGGGLEL 97
Cdd:PRK08788   65 PVDFWVLASDVPGVFNLGGDLalfaeliraGDRDALLAyARACV-----DGVHAFHRGFgaGAISIALVQGDALGGGFEA 139
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217268801  98 ALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVnHAVAQNEEGDAA 174
Cdd:PRK08788  140 ALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEELHDMGLV-DVLVEDGQGEAA 215
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
1-185 4.72e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 75.85  E-value: 4.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKE-REQMSEAEVGVFVQRLRGLMNDIAAFP 79
Cdd:PRK08272   25 LNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKG-FCAGYDLSAyAEGSSSGGGGGAYPGKRQAVNHLPDDP 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 ------------------------APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIET-TRGLLPGAGGTQRlprc 134
Cdd:PRK08272  104 wdpmidyqmmsrfvrgfmslwhahKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTrVWGVPATGMWAYR---- 179
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2217268801 135 LGVALAKELIFTGRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 185
Cdd:PRK08272  180 LGPQRAKRLLFTGDCITGAQAAEWGLAVEAV----PPEELDERTERLVERI 226
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
3-169 2.25e-14

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 70.48  E-value: 2.25e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   3 RPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKE-REQMSEAEVGVFVQR-LRGLMNDIAAFPA 80
Cdd:PRK07112   21 RPEAQNTINDRLIAECMDVLDRCEHAATIVVL---EGLPEVFCFGADFSAiAEKPDAGRADLIDAEpLYDLWHRLATGPY 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  81 PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPgAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 160
Cdd:PRK07112   98 VTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP-ACVLPFLIRRIGTQKAHYMTLMTQPVTAQQAFSWGL 176

                  ....*....
gi 2217268801 161 VNHAVAQNE 169
Cdd:PRK07112  177 VDAYGANSD 185
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
1-165 3.37e-14

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 70.98  E-value: 3.37e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLK-----EREQMSEAEVgvfVQRLRGLMNDI 75
Cdd:PLN02874   26 LNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIK-GAGRAFSAGGDLKmfydgRESDDSCLEV---VYRMYWLCYHI 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  76 AAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGvALAKELIFTGRRLSGTEA 155
Cdd:PLN02874  102 HTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPG-HLGEYLALTGARLNGKEM 180
                         170
                  ....*....|
gi 2217268801 156 HVLGLVNHAV 165
Cdd:PLN02874  181 VACGLATHFV 190
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
1-163 6.09e-14

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 70.39  E-value: 6.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGAD-LKEREQMSEA---EVGVFVQRLRGLMNDIA 76
Cdd:PLN02851   57 LNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMK-GSGRAFCSGADvVSLYHLINEGnveECKLFFENLYKFVYLQG 135
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGT---QRLPRCLGVALAkeliFTGRRLSGT 153
Cdd:PLN02851  136 TYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASyylSRLPGYLGEYLA----LTGQKLNGV 211
                         170
                  ....*....|
gi 2217268801 154 EAHVLGLVNH 163
Cdd:PLN02851  212 EMIACGLATH 221
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
1-161 7.00e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 69.00  E-value: 7.00e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIA---- 76
Cdd:PRK07260   17 LNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDEDDVQSLVKIAELVNEISfaik 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 156
Cdd:PRK07260   96 QLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRATHLAMTGEALTAEKAL 175

                  ....*
gi 2217268801 157 VLGLV 161
Cdd:PRK07260  176 EYGFV 180
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
18-183 9.09e-14

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 69.14  E-value: 9.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  18 LLETLAQLREDRQVRVLLFRSGV-KGVFCAGADLKE--REQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGG 94
Cdd:PLN03214   43 LDDALTALENDPTVRGVVFASGLrRDVFTAGNDIAElyAPKTSAARYAEFWLTQTTFLVRLLRSRLATVCAIRGACPAGG 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  95 LELALACDLRVAASSAVMGLIETTRGL-LPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDA 173
Cdd:PLN03214  123 CAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAALMEA 202
                         170
                  ....*....|
gi 2217268801 174 AYQRARALAQ 183
Cdd:PLN03214  203 AASAMERALK 212
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
1-235 5.20e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 66.35  E-value: 5.20e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEReqMSEAEVGV-FVQRLRGLMNDIAAFP 79
Cdd:PRK06023   21 FNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFL-GTEGCFSAGNDMQDF--LAAAMGGTsFGSEILDFLIALAEAE 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  80 APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 159
Cdd:PRK06023   98 KPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAEAAQEAG 177
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217268801 160 LVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIdRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAF 235
Cdd:PRK06023  178 LIWKIVDE----EAVEAETLKAAEELAAKPPQALQIARDLM-RGPREDILARIDEEAKHFAARLKSAEARAAFEAF 248
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
1-165 8.58e-13

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 67.05  E-value: 8.58e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADL----KEREQMSEAEVGVFVQRLRGLMNDIA 76
Cdd:PLN02988   24 LNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILK-GHGRAFCAGGDVaavvRDIEQGNWRLGANFFSDEYMLNYVMA 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVaLAKELIFTGRRLSGTEAH 156
Cdd:PLN02988  103 TYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYVGLTGARLDGAEML 181

                  ....*....
gi 2217268801 157 VLGLVNHAV 165
Cdd:PLN02988  182 ACGLATHFV 190
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
1-169 2.78e-12

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 65.48  E-value: 2.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE----REQMSEAEVGVFVQRLRGLMNDIA 76
Cdd:PLN02157   52 LNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMK-GSGRAFCAGGDIVSlyhlRKRGSPDAIREFFSSLYSFIYLLG 130
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  77 AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGvALAKELIFTGRRLSGTEAH 156
Cdd:PLN02157  131 TYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPG-RLGEYLGLTGLKLSGAEML 209
                         170
                  ....*....|...
gi 2217268801 157 VLGLVNHAVAQNE 169
Cdd:PLN02157  210 ACGLATHYIRSEE 222
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
1-165 3.48e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 53.04  E-value: 3.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADL--------------------KEREQMSEAE 60
Cdd:PRK12478   20 LNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLR-GAGRAFSGGYDFgggfqhwgeammtdgrwdpgKDFAMVTARE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  61 VGVfVQRLRGlmndIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGlieTTRGLLPGAGGTQRLPRCLGVALA 140
Cdd:PRK12478   99 TGP-TQKFMA----IWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIG---TPYSRMWGAYLTGMWLYRLSLAKV 170
                         170       180
                  ....*....|....*....|....*
gi 2217268801 141 KELIFTGRRLSGTEAHVLGLVNHAV 165
Cdd:PRK12478  171 KWHSLTGRPLTGVQAAEAELINEAV 195
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
8-183 4.89e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 49.20  E-value: 4.89e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801   8 NALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQMSEAEVGVfVQRLRGLMNDIAAFPAPTIAAMD 87
Cdd:PRK06213   24 NALSPAMIDALNAALDQAEDDRAVVVI---TGQPGIFSGGFDLKVMTSGAQAAIAL-LTAGSTLARRLLSHPKPVIVACT 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  88 GFALGGGLELALACDLRVAASSAV-MGLIETTRGL-LPGAG---GTQRLPRclgVALAKELIfTGRRLSGTEAHVLGLVN 162
Cdd:PRK06213  100 GHAIAKGAFLLLSADYRIGVHGPFkIGLNEVAIGMtMPHAAielARDRLTP---SAFQRAVI-NAEMFDPEEAVAAGFLD 175
                         170       180
                  ....*....|....*....|.
gi 2217268801 163 HAVAQNEEGDAAYQRARALAQ 183
Cdd:PRK06213  176 EVVPPEQLLARAQAAARELAG 196
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
10-203 1.79e-05

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 44.70  E-value: 1.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  10 LGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK--EREQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMD 87
Cdd:PLN02267   23 LNPTLIDSIRSALRQVKSQATPGSVLITTAEGKFFSNGFDLAwaQAAGSAPSRLHLMVAKLRPLVADLISLPMPTIAAVT 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268801  88 GFALGGGLELALACDLRvaassavmgLIETTRGLLPGAGGTQRLP---------RC-LGVALA-KELIFTGRRLSGTEAH 156
Cdd:PLN02267  103 GHASAAGFILALSHDYV---------LMRKDRGVLYMSEVDIGLPlpdyfmallRAkIGSPAArRDVLLRAAKLTAEEAV 173
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2217268801 157 VLGLVnhavaqneegDAAYQRARALAQEilpqapiAVRLGKVAIDRG 203
Cdd:PLN02267  174 EMGIV----------DSAHDSAEETVEA-------AVRLGEELAARK 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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