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Conserved domains on  [gi|2217276433|ref|XP_047280893|]
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polyunsaturated fatty acid 5-lipoxygenase isoform X3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Lipoxygenase super family cl37981
Lipoxygenase;
82-520 3.74e-71

Lipoxygenase;


The actual alignment was detected with superfamily member pfam00305:

Pssm-ID: 459754 [Multi-domain]  Cd Length: 672  Bit Score: 239.70  E-value: 3.74e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  82 WQEDLMFGYQFLNGCNPVLIRRCTELP--EKL-P---------VTTEMVECSLERqLSLEQEVQQGNIFIVDFE-----L 144
Cdd:pfam00305 189 WLRDEEFARQTLAGLNPVSIRLLTEFPpkSKLdPeiygpqesaITEEHIEKQLEG-LTVEEALEQKKLFILDYHdlllpY 267
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 145 LDGIDANK-------------TDPCTLQflaapicllyknlankivPIAIQLNQIPGDENP-----IFLP-SDAKYDWL- 204
Cdd:pfam00305 268 LNRINALEgtklyasrtllflTDDGTLK------------------PLAIELSLPPSGGKHpqwkrVFTPaSDGTEDWLw 329
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 205 -LAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANAT 283
Cdd:pfam00305 330 qLAKAHVAVNDSGYHQLVSHWLRTHAVMEPFIIATNRQLSVMHPIYKLLHPHFRYTMEINALARQSLINAGGIIESTFFP 409
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 284 GGGGhVQMVQRAMKDL---TYASLcfPEAIKARGMeSKED----------IPYYFYRDDGLLVWEAIRTFTAEVVDIYYE 350
Cdd:pfam00305 410 GKYS-MEMSSVAYKDLwrfDEQAL--PADLIKRGM-AVEDpsaphglrllIEDYPYANDGLEIWDAIKQWVTDYVNHYYP 485
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 351 GDQVVEEDPELQDFVNDVYVYGmRGRKS--SGFPKsVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMR 428
Cdd:pfam00305 486 DDSAVQSDTELQAWWKEVREVG-HGDKKdePWWPK-LDTKEDLIEILTTIIWIASAHHAAVNFGQYPYAGYFPNRPTISR 563
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 429 APPPTaKGVVTIEQIV--------DTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKP-VKEAMARFRKNLEA 499
Cdd:pfam00305 564 RLMPE-EGTPEYEEFLenpekfflSTIPSQLQATLVMAVLEILSTHSPDEEYLGQRDEPSWTSDPeILAAFERFSAKLKE 642
                         490       500       510
                  ....*....|....*....|....*....|
gi 2217276433 500 IVSVIAERNKKKQL---------PYYYLSP 520
Cdd:pfam00305 643 IEGIIDERNKDPKLknrcgpgvvPYELLKP 672
 
Name Accession Description Interval E-value
Lipoxygenase pfam00305
Lipoxygenase;
82-520 3.74e-71

Lipoxygenase;


Pssm-ID: 459754 [Multi-domain]  Cd Length: 672  Bit Score: 239.70  E-value: 3.74e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  82 WQEDLMFGYQFLNGCNPVLIRRCTELP--EKL-P---------VTTEMVECSLERqLSLEQEVQQGNIFIVDFE-----L 144
Cdd:pfam00305 189 WLRDEEFARQTLAGLNPVSIRLLTEFPpkSKLdPeiygpqesaITEEHIEKQLEG-LTVEEALEQKKLFILDYHdlllpY 267
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 145 LDGIDANK-------------TDPCTLQflaapicllyknlankivPIAIQLNQIPGDENP-----IFLP-SDAKYDWL- 204
Cdd:pfam00305 268 LNRINALEgtklyasrtllflTDDGTLK------------------PLAIELSLPPSGGKHpqwkrVFTPaSDGTEDWLw 329
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 205 -LAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANAT 283
Cdd:pfam00305 330 qLAKAHVAVNDSGYHQLVSHWLRTHAVMEPFIIATNRQLSVMHPIYKLLHPHFRYTMEINALARQSLINAGGIIESTFFP 409
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 284 GGGGhVQMVQRAMKDL---TYASLcfPEAIKARGMeSKED----------IPYYFYRDDGLLVWEAIRTFTAEVVDIYYE 350
Cdd:pfam00305 410 GKYS-MEMSSVAYKDLwrfDEQAL--PADLIKRGM-AVEDpsaphglrllIEDYPYANDGLEIWDAIKQWVTDYVNHYYP 485
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 351 GDQVVEEDPELQDFVNDVYVYGmRGRKS--SGFPKsVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMR 428
Cdd:pfam00305 486 DDSAVQSDTELQAWWKEVREVG-HGDKKdePWWPK-LDTKEDLIEILTTIIWIASAHHAAVNFGQYPYAGYFPNRPTISR 563
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 429 APPPTaKGVVTIEQIV--------DTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKP-VKEAMARFRKNLEA 499
Cdd:pfam00305 564 RLMPE-EGTPEYEEFLenpekfflSTIPSQLQATLVMAVLEILSTHSPDEEYLGQRDEPSWTSDPeILAAFERFSAKLKE 642
                         490       500       510
                  ....*....|....*....|....*....|
gi 2217276433 500 IVSVIAERNKKKQL---------PYYYLSP 520
Cdd:pfam00305 643 IEGIIDERNKDPKLknrcgpgvvPYELLKP 672
PLN02337 PLN02337
lipoxygenase
20-529 5.83e-62

lipoxygenase


Pssm-ID: 215193 [Multi-domain]  Cd Length: 866  Bit Score: 218.01  E-value: 5.83e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  20 PRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIF------VKISN--------------------- 72
Cdd:PLN02337  261 PRDERFGHLKMSDFLAYALKAIAQVLVPELEALFDKTPNEFDSFEDVLklyeggIKLPNgplleelrkniplemlkellr 340
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  73 TISERV----MNH--------WQEDLMFGYQFLNGCNPVLIRRCTELPEKL------------PVTTEMVECSLErQLSL 128
Cdd:PLN02337  341 TDGEYLlkfpMPQvikedksaWRTDEEFAREMLAGVNPVVIRRLTEFPPKSkldpkkygdqnsSITEEHIEKNLE-GLTV 419
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 129 EQEVQQGNIFIVDFEllDG-----IDANKTDPCTLqflaAPICLLYKNLANKIVPIAIQLN--QIPGDE----NPIFLPS 197
Cdd:PLN02337  420 QEALEKNRLFILDHH--DAlmpylRRINSTSTKTY----ATRTLLFLKDDGTLKPLAIELSlpHPQGDKfgavSKVYTPA 493
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 198 DAKYD---WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICEC 274
Cdd:PLN02337  494 EDGVEgsvWQLAKAYVAVNDSGYHQLISHWLNTHAVIEPFVIATNRQLSVLHPIHKLLHPHFRDTMNINALARQILINAG 573
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 275 GLFDKANATGGGGhVQMVQRAMKDLTYASLCFPEAIKARGMeSKED----------IPYYFYRDDGLLVWEAIRTFTAEV 344
Cdd:PLN02337  574 GILESTVFPGKYA-LEMSSVVYKNWNFTEQALPADLIKRGV-AVEDpssphgvrllIEDYPYAVDGLEIWSAIETWVKEY 651
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 345 VDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAP 424
Cdd:PLN02337  652 CAFYYPTDDMVQGDTELQSWWKEVREEGHGDLKDEPWWPKMQTVAELIESCTIIIWIASALHAAVNFGQYPYAGYLPNRP 731
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 425 PTMRAPPPtAKG---------------VVTIEQIVDTLpdrgrscwhLGA--VWALSQFQENELFLGM--YPEEHFIEKP 485
Cdd:PLN02337  732 TVSRRFMP-EPGtpeyeeleknpdkafLKTITAQLQTL---------LGIslIEILSRHSSDEVYLGQrdTPEWTSDAEP 801
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217276433 486 VkEAMARFRKNLEAIVSVIAERNKKKQL---------PYYYLSPDR-------------IPNSVAI 529
Cdd:PLN02337  802 L-EAFKRFGERLVEIENRIVDMNKDPRLknrvgpvkmPYTLLYPNTsdytgeggltgkgIPNSVSI 866
 
Name Accession Description Interval E-value
Lipoxygenase pfam00305
Lipoxygenase;
82-520 3.74e-71

Lipoxygenase;


Pssm-ID: 459754 [Multi-domain]  Cd Length: 672  Bit Score: 239.70  E-value: 3.74e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  82 WQEDLMFGYQFLNGCNPVLIRRCTELP--EKL-P---------VTTEMVECSLERqLSLEQEVQQGNIFIVDFE-----L 144
Cdd:pfam00305 189 WLRDEEFARQTLAGLNPVSIRLLTEFPpkSKLdPeiygpqesaITEEHIEKQLEG-LTVEEALEQKKLFILDYHdlllpY 267
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 145 LDGIDANK-------------TDPCTLQflaapicllyknlankivPIAIQLNQIPGDENP-----IFLP-SDAKYDWL- 204
Cdd:pfam00305 268 LNRINALEgtklyasrtllflTDDGTLK------------------PLAIELSLPPSGGKHpqwkrVFTPaSDGTEDWLw 329
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 205 -LAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANAT 283
Cdd:pfam00305 330 qLAKAHVAVNDSGYHQLVSHWLRTHAVMEPFIIATNRQLSVMHPIYKLLHPHFRYTMEINALARQSLINAGGIIESTFFP 409
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 284 GGGGhVQMVQRAMKDL---TYASLcfPEAIKARGMeSKED----------IPYYFYRDDGLLVWEAIRTFTAEVVDIYYE 350
Cdd:pfam00305 410 GKYS-MEMSSVAYKDLwrfDEQAL--PADLIKRGM-AVEDpsaphglrllIEDYPYANDGLEIWDAIKQWVTDYVNHYYP 485
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 351 GDQVVEEDPELQDFVNDVYVYGmRGRKS--SGFPKsVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMR 428
Cdd:pfam00305 486 DDSAVQSDTELQAWWKEVREVG-HGDKKdePWWPK-LDTKEDLIEILTTIIWIASAHHAAVNFGQYPYAGYFPNRPTISR 563
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 429 APPPTaKGVVTIEQIV--------DTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKP-VKEAMARFRKNLEA 499
Cdd:pfam00305 564 RLMPE-EGTPEYEEFLenpekfflSTIPSQLQATLVMAVLEILSTHSPDEEYLGQRDEPSWTSDPeILAAFERFSAKLKE 642
                         490       500       510
                  ....*....|....*....|....*....|
gi 2217276433 500 IVSVIAERNKKKQL---------PYYYLSP 520
Cdd:pfam00305 643 IEGIIDERNKDPKLknrcgpgvvPYELLKP 672
PLN02337 PLN02337
lipoxygenase
20-529 5.83e-62

lipoxygenase


Pssm-ID: 215193 [Multi-domain]  Cd Length: 866  Bit Score: 218.01  E-value: 5.83e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  20 PRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIF------VKISN--------------------- 72
Cdd:PLN02337  261 PRDERFGHLKMSDFLAYALKAIAQVLVPELEALFDKTPNEFDSFEDVLklyeggIKLPNgplleelrkniplemlkellr 340
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  73 TISERV----MNH--------WQEDLMFGYQFLNGCNPVLIRRCTELPEKL------------PVTTEMVECSLErQLSL 128
Cdd:PLN02337  341 TDGEYLlkfpMPQvikedksaWRTDEEFAREMLAGVNPVVIRRLTEFPPKSkldpkkygdqnsSITEEHIEKNLE-GLTV 419
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 129 EQEVQQGNIFIVDFEllDG-----IDANKTDPCTLqflaAPICLLYKNLANKIVPIAIQLN--QIPGDE----NPIFLPS 197
Cdd:PLN02337  420 QEALEKNRLFILDHH--DAlmpylRRINSTSTKTY----ATRTLLFLKDDGTLKPLAIELSlpHPQGDKfgavSKVYTPA 493
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 198 DAKYD---WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICEC 274
Cdd:PLN02337  494 EDGVEgsvWQLAKAYVAVNDSGYHQLISHWLNTHAVIEPFVIATNRQLSVLHPIHKLLHPHFRDTMNINALARQILINAG 573
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 275 GLFDKANATGGGGhVQMVQRAMKDLTYASLCFPEAIKARGMeSKED----------IPYYFYRDDGLLVWEAIRTFTAEV 344
Cdd:PLN02337  574 GILESTVFPGKYA-LEMSSVVYKNWNFTEQALPADLIKRGV-AVEDpssphgvrllIEDYPYAVDGLEIWSAIETWVKEY 651
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 345 VDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAP 424
Cdd:PLN02337  652 CAFYYPTDDMVQGDTELQSWWKEVREEGHGDLKDEPWWPKMQTVAELIESCTIIIWIASALHAAVNFGQYPYAGYLPNRP 731
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 425 PTMRAPPPtAKG---------------VVTIEQIVDTLpdrgrscwhLGA--VWALSQFQENELFLGM--YPEEHFIEKP 485
Cdd:PLN02337  732 TVSRRFMP-EPGtpeyeeleknpdkafLKTITAQLQTL---------LGIslIEILSRHSSDEVYLGQrdTPEWTSDAEP 801
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217276433 486 VkEAMARFRKNLEAIVSVIAERNKKKQL---------PYYYLSPDR-------------IPNSVAI 529
Cdd:PLN02337  802 L-EAFKRFGERLVEIENRIVDMNKDPRLknrvgpvkmPYTLLYPNTsdytgeggltgkgIPNSVSI 866
PLN02305 PLN02305
lipoxygenase
82-529 6.52e-56

lipoxygenase


Pssm-ID: 215174 [Multi-domain]  Cd Length: 918  Bit Score: 201.68  E-value: 6.52e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  82 WQEDLMFGYQFLNGCNPVLIRRCTELP--EKL------PVTTEMVECSLERQL---SLEQEVQQGNIFIVDFE--LLDGI 148
Cdd:PLN02305  417 WLRDNEFARQALAGVNPVNIEILKEFPilSKLdpavygPPESALTEELIERELegmTVEKAIEEKRLFILDYHdmLLPFI 496
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 149 DANKTDPCTLQFlaAPICLLYKNLANKIVPIAIQLNQIPGDENP----IFLPS-DAKYDWL--LAKIWVRSSDFHVHQTI 221
Cdd:PLN02305  497 EKMNSLPERKAY--ASRTVFFYSKAGALRPIAIELSLPPTPSSPgnkfVYTHGhDATTHWIwkLAKAHVCSNDAGVHQLV 574
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 222 THLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDkANATGGGGHVQMVQRAMKDL-T 300
Cdd:PLN02305  575 NHWLRTHACMEPYIIATHRQLSAMHPIYKLLHPHMRYTLEINALARQSLINGGGIIE-ACFSPGKYAMELSSAAYKSMwR 653
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 301 YASLCFPEAIKARGMeSKED----------IPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYV 370
Cdd:PLN02305  654 FDMEALPADLIRRGM-AEEDpsmpcgvrlvIEDYPYAADGLLIWSAIKEWVESYVDHFYSEPNSITSDLELQAWWDEIKN 732
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 371 YGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRA------PPPTAKGVVTIEQ-I 443
Cdd:PLN02305  733 KGHYDKRNEPWWPKLNTKEDLSGILTTMIWIASGQHAAINFGQYPFGGYVPNRPTLMRKlipqenDPDYEKFIRNPQYtF 812
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 444 VDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPE--EHFIEKP-VKEAMARFRKNLEAIVSVIAERNKKKQL------- 513
Cdd:PLN02305  813 LSSLPTQLQATKVMAVQDTLSTHSPDEEYLGELRHlhSHWINDHeVVKLFNKFSARLEEIEKTINERNKDIRLknrngag 892
                         490       500
                  ....*....|....*....|....*.
gi 2217276433 514 --PYYYLSPDR--------IPNSVAI 529
Cdd:PLN02305  893 ipPYELLLPTSgpgvtgrgIPNSISI 918
PLN02264 PLN02264
lipoxygenase
19-529 2.38e-54

lipoxygenase


Pssm-ID: 215148 [Multi-domain]  Cd Length: 919  Bit Score: 197.08  E-value: 2.38e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  19 LPRDIQFDSEKGVDFVLNYSKA-MENLFINRFMHMFQSSWNDFADFEKIF--------------------VKISNTISE- 76
Cdd:PLN02264  320 VPRDEQFEESKQDTFAAGRLKAvLHNLIPSLKASILAEDFANFGEIDSLYkeglllklgfqddifkkfplPKVVTTLQEs 399
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433  77 --------------RVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEM---VECSLERQ--------LSLEQE 131
Cdd:PLN02264  400 segllkydtpkilsKDKFAWLRDDEFARQAIAGINPVNIERVKVFPPVSNLDPEIygpQHSALTEDhiighldgLSVQQA 479
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 132 VQQGNIFIVDFE-----LLDGI---DANKTDPCTLQFLAAPICLLYknlankivPIAIQLNQIPGDENP-----IFLPSD 198
Cdd:PLN02264  480 LEENRLFMVDYHdiylpFLDRInalDGRKAYATRTIFFLTRLGTLK--------PIAIELSLPPSGPNSrskrvVTPPVD 551
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 199 AKYDWL--LAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGL 276
Cdd:PLN02264  552 ATSNWMwqLAKAHVCSNDAGVHQLVNHWLRTHACLEPFILAAHRQLSAMHPIFKLLDPHMRYTLEINALARQTLISADGV 631
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 277 FDKAnATGGGGHVQMVQRAMK------------DLTYASLCFPEAIKARGMesKEDIPYYFYRDDGLLVWEAIRTFTAEV 344
Cdd:PLN02264  632 IESC-FTAGQYGMEISAAAYKnswrfdmeglpaDLIRRGMAVPDPTQPHGL--KLLIEDYPYANDGLLLWSAIQTWVRTY 708
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 345 VDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAP 424
Cdd:PLN02264  709 VERYYPDPSLICTDKELQAWYSESINVGHADLRDADWWPKLSTVDDLVSILTTLIWLASAQHAALNFGQYPYGGYVPNRP 788
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276433 425 PTMRAPPPTAKGVVTIEQIVD-------TLPDRGRSCWHLGAVWALSQFQENELFLG--MYPEEHFIEKPVKEAMARFRK 495
Cdd:PLN02264  789 PLMRRLIPDESDPEYASFLADpqkyyfsSMPSLLQTTKFMAVVDTLSTHSPDEEYIGerQQPSIWTGDAEIVEAFYGFSA 868
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2217276433 496 NLEAIVSVIAERNKKKQ---------LPYYYLSPDR--------IPNSVAI 529
Cdd:PLN02264  869 EIGRIEKEIEKRNADPSrrnrcgagvLPYELLAPSSepgvtcrgVPNSVSI 919
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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