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Conserved domains on  [gi|2217276844|ref|XP_047281062|]
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janus kinase and microtubule-interacting protein 3 isoform X2 [Homo sapiens]

Protein Classification

SMC_prok_B and JAKMIP_CC3 domain-containing protein( domain architecture ID 13531091)

SMC_prok_B and JAKMIP_CC3 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
JAKMIP_CC3 pfam16034
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
429-625 5.44e-93

JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.


:

Pssm-ID: 464986 [Multi-domain]  Cd Length: 199  Bit Score: 293.32  E-value: 5.44e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 429 ERDKLLRFRKQRKKMAKLPKP-VVVETFFGYDEEASLESDGSSVSYQTDRTDQTPCTPDDDLEEGMAKEETELRFRQLTM 507
Cdd:pfam16034   1 ERDKLIRARKQRRKEKKKKLRdMVVETFFGYDEEASVDSETSSLSYNTDRTDSTPATPDEDLDEGVAAEEAELRFRQLTR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 508 EYQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQALYRRNQELVEKIKQM 587
Cdd:pfam16034  81 EYQALQRAYALLQEQSGGTLDAEREAKTREQLQAELRRAQSRIEDLESALAQKGQDSKWVEEKQALIRRNQELVEKIRIM 160
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2217276844 588 ETEEARLRHEVQDARDQNELLEFRILELEERERKSPAI 625
Cdd:pfam16034 161 EQEEGRLKNEIQDARDQNELLEFRILELEERERRSPAI 198
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-830 1.28e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 1.28e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   27 DLRAKLTDIQIELQ--QEKSKVSKVEREKNQELRQVREHEQHKTAVLLTELKtklHEEKMKELQAVRETLLRQhEAELLR 104
Cdd:TIGR02168  217 ELKAELRELELALLvlRLEELREELEELQEELKEAEEELEELTAELQELEEK---LEELRLEVSELEEEIEEL-QKELYA 292
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  105 VIKIKDNENQRLQALLSALRDGGPEKVKTVLLSEAKEEAKKGFEVEKVKMQQEISELKGakrqveealtlVIQADKIKAA 184
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE-----------ELESLEAELE 361
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  185 EIRSVyhlhQEEITRIKKECEREIRRLmeeikfkDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREADRhpgspr 264
Cdd:TIGR02168  362 ELEAE----LEELESRLEELEEQLETL-------RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE------ 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  265 relphaagagdasdhsgSPEQQLDEKDARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRL 344
Cdd:TIGR02168  425 -----------------ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  345 SRKNEDLSHALRRMENKLKFVTQENIEMRQRAGIIRRPSSLNDLDqSQDEREVDflklqIVEQQNLIDELSKTLETAGYV 424
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIE-----AALGGRLQAVVVENLNAAKKA 561
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  425 KSVLERDKLLRfrkqrkkMAKLPKPVVVETFFGYDEEASLESDGSSVSYQTDRTDQTP------------CTPDDDLEEG 492
Cdd:TIGR02168  562 IAFLKQNELGR-------VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggVLVVDDLDNA 634
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  493 MA-KEETELRFRQLTMEYQALQRAYALLQ---EQVGGTLDAEREVktrEQLQAEVQRAQARIEDLEKALAE---QGQDMK 565
Cdd:TIGR02168  635 LElAKKLRPGYRIVTLDGDLVRPGGVITGgsaKTNSSILERRREI---EELEEKIEELEEKIAELEKALAElrkELEELE 711
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  566 wiEEKQALYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERERKSPAIsfhhtpfVDGKSPLQVYCEA 645
Cdd:TIGR02168  712 --EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER-------LEEAEEELAEAEA 782
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  646 EgvtdivVAELMKKLDILGDNANLTNEEQVvviQARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEE 725
Cdd:TIGR02168  783 E------IEELEAQIEQLKEELKALREALD---ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  726 LDYRKQALDQANKHILELEAMLYDALQQEAGAKVAELLSEEEREKLkvaveqwkrqvMSELRERDAQILRERmELLQLAQ 805
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL-----------SEELRELESKRSELR-RELEELR 921
                          810       820
                   ....*....|....*....|....*
gi 2217276844  806 QRIKELEERIEAQKRQIKELEEKLS 830
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLS 946
 
Name Accession Description Interval E-value
JAKMIP_CC3 pfam16034
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
429-625 5.44e-93

JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.


Pssm-ID: 464986 [Multi-domain]  Cd Length: 199  Bit Score: 293.32  E-value: 5.44e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 429 ERDKLLRFRKQRKKMAKLPKP-VVVETFFGYDEEASLESDGSSVSYQTDRTDQTPCTPDDDLEEGMAKEETELRFRQLTM 507
Cdd:pfam16034   1 ERDKLIRARKQRRKEKKKKLRdMVVETFFGYDEEASVDSETSSLSYNTDRTDSTPATPDEDLDEGVAAEEAELRFRQLTR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 508 EYQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQALYRRNQELVEKIKQM 587
Cdd:pfam16034  81 EYQALQRAYALLQEQSGGTLDAEREAKTREQLQAELRRAQSRIEDLESALAQKGQDSKWVEEKQALIRRNQELVEKIRIM 160
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2217276844 588 ETEEARLRHEVQDARDQNELLEFRILELEERERKSPAI 625
Cdd:pfam16034 161 EQEEGRLKNEIQDARDQNELLEFRILELEERERRSPAI 198
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-830 1.28e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 1.28e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   27 DLRAKLTDIQIELQ--QEKSKVSKVEREKNQELRQVREHEQHKTAVLLTELKtklHEEKMKELQAVRETLLRQhEAELLR 104
Cdd:TIGR02168  217 ELKAELRELELALLvlRLEELREELEELQEELKEAEEELEELTAELQELEEK---LEELRLEVSELEEEIEEL-QKELYA 292
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  105 VIKIKDNENQRLQALLSALRDGGPEKVKTVLLSEAKEEAKKGFEVEKVKMQQEISELKGakrqveealtlVIQADKIKAA 184
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE-----------ELESLEAELE 361
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  185 EIRSVyhlhQEEITRIKKECEREIRRLmeeikfkDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREADRhpgspr 264
Cdd:TIGR02168  362 ELEAE----LEELESRLEELEEQLETL-------RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE------ 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  265 relphaagagdasdhsgSPEQQLDEKDARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRL 344
Cdd:TIGR02168  425 -----------------ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  345 SRKNEDLSHALRRMENKLKFVTQENIEMRQRAGIIRRPSSLNDLDqSQDEREVDflklqIVEQQNLIDELSKTLETAGYV 424
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIE-----AALGGRLQAVVVENLNAAKKA 561
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  425 KSVLERDKLLRfrkqrkkMAKLPKPVVVETFFGYDEEASLESDGSSVSYQTDRTDQTP------------CTPDDDLEEG 492
Cdd:TIGR02168  562 IAFLKQNELGR-------VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggVLVVDDLDNA 634
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  493 MA-KEETELRFRQLTMEYQALQRAYALLQ---EQVGGTLDAEREVktrEQLQAEVQRAQARIEDLEKALAE---QGQDMK 565
Cdd:TIGR02168  635 LElAKKLRPGYRIVTLDGDLVRPGGVITGgsaKTNSSILERRREI---EELEEKIEELEEKIAELEKALAElrkELEELE 711
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  566 wiEEKQALYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERERKSPAIsfhhtpfVDGKSPLQVYCEA 645
Cdd:TIGR02168  712 --EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER-------LEEAEEELAEAEA 782
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  646 EgvtdivVAELMKKLDILGDNANLTNEEQVvviQARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEE 725
Cdd:TIGR02168  783 E------IEELEAQIEQLKEELKALREALD---ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  726 LDYRKQALDQANKHILELEAMLYDALQQEAGAKVAELLSEEEREKLkvaveqwkrqvMSELRERDAQILRERmELLQLAQ 805
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL-----------SEELRELESKRSELR-RELEELR 921
                          810       820
                   ....*....|....*....|....*
gi 2217276844  806 QRIKELEERIEAQKRQIKELEEKLS 830
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLS 946
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
495-838 4.61e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 4.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 495 KEETELRFRQLTMEYQALQRAYALLQEQVG-GTLDAEREVKTREQLQAEVQRAQARIEDLEKALAE-QGQDMKWIEEKQA 572
Cdd:COG1196   220 EELKELEAELLLLKLRELEAELEELEAELEeLEAELEELEAELAELEAELEELRLELEELELELEEaQAEEYELLAELAR 299
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 573 LYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERErkspaisfhhtpfvdgksplqvyceaegvtdiv 652
Cdd:COG1196   300 LEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL--------------------------------- 346
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 653 vAELMKKLDilgdnanltnEEQVVVIQARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQA 732
Cdd:COG1196   347 -EEAEEELE----------EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 733 LDQANKHILELEAmlydALQQEAGAKVAELLSEEEREKLKVAVEQwkrqvmsELRERDAQILRERMELLQLAQQRIKELE 812
Cdd:COG1196   416 LERLEEELEELEE----ALAELEEEEEEEEEALEEAAEEEAELEE-------EEEALLELLAELLEEAALLEAALAELLE 484
                         330       340
                  ....*....|....*....|....*.
gi 2217276844 813 ERIEAQKRQIKELEEKLSFSGHSPSW 838
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGFLEGV 510
PTZ00121 PTZ00121
MAEBL; Provisional
36-621 4.28e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 4.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   36 QIELQQEKSKVSKVER-EKNQELRQVREHEQHKTAVLLTELKTKLHEEKMKELQAVRETllRQHEAELLRVIKIKDNENQ 114
Cdd:PTZ00121  1177 KAEAARKAEEVRKAEElRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEA--KKDAEEAKKAEEERNNEEI 1254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  115 RlqallsALRDGGPEKVKTVLLSEAKEEAKKGFEVEKVKMQQEISELKGA--KRQVEEAltlviqadKIKAAEIRSVYHL 192
Cdd:PTZ00121  1255 R------KFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAeeKKKADEA--------KKKAEEAKKADEA 1320
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  193 hQEEITRIKKECErEIRRLMEEIKFKDRAVfvlERELGVQAGHAQRLQLQKEALDEQLSQVREADRHPGSPRRELPHAAG 272
Cdd:PTZ00121  1321 -KKKAEEAKKKAD-AAKKKAEEAKKAAEAA---KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE 1395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  273 AGDASDHSGSPEQQLDEKDARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRLSRKNEDLS 352
Cdd:PTZ00121  1396 AKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEA 1475
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  353 HALRRMENKLKFVTQENIEMRQRAGIIRRPSS----LNDLDQSQDEREVDflKLQIVEQQNLIDELSKTLEtagyVKSVL 428
Cdd:PTZ00121  1476 KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEakkkADEAKKAEEAKKAD--EAKKAEEAKKADEAKKAEE----KKKAD 1549
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  429 ERDKLLRFRKQRKKMAklpkpvvVETFFGYDEEASLESDGSSVSYQTDRTDQTPCTPDDDLEEGMAKEETElRFRQLTME 508
Cdd:PTZ00121  1550 ELKKAEELKKAEEKKK-------AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK-KAEEAKIK 1621
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  509 YQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQARIEDLEKALAE---QGQDMKWIEEK-----QALYRRNQEL 580
Cdd:PTZ00121  1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkKAEEAKKAEEDekkaaEALKKEAEEA 1701
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 2217276844  581 --VEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERERK 621
Cdd:PTZ00121  1702 kkAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
496-620 5.11e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 5.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  496 EETELRFRQLTMEYQALQRAYALLQEQvggtLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWI----EEKQ 571
Cdd:COG4913    620 AELEEELAEAEERLEALEAELDALQER----REALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLaaleEQLE 695
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 2217276844  572 ALYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERER 620
Cdd:COG4913    696 ELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR 744
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
531-847 9.87e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 9.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 531 REVKTREQL-------QAEVQRAQARIEDLEKALAEQGQDMKWI---EEKQALYR-RNQELVEKIKQM-ETEEARLRHEV 598
Cdd:pfam17380 310 REVERRRKLeeaekarQAEMDRQAAIYAEQERMAMERERELERIrqeERKRELERiRQEEIAMEISRMrELERLQMERQQ 389
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 599 QDARDQNELLEFRILELEERERKspaisfhhtpfvdgKSPLQVYCEAEGVTdivvaelmkkldilgdnanlTNEEQVVVI 678
Cdd:pfam17380 390 KNERVRQELEAARKVKILEEERQ--------------RKIQQQKVEMEQIR--------------------AEQEEARQR 435
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 679 QARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHI-LELEAMLYDALQQEAGA 757
Cdd:pfam17380 436 EVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILeKELEERKQAMIEEERKR 515
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 758 KVAELLSE-------EEREKLKVAVEQWKRQVMSELRERDAQILRERMELLQL-AQQRIKELEERIEAQKRQIKELEEKL 829
Cdd:pfam17380 516 KLLEKEMEerqkaiyEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLeAMEREREMMRQIVESEKARAEYEATT 595
                         330       340
                  ....*....|....*....|...
gi 2217276844 830 SFSGHSPSWHPDV-----PHIES 847
Cdd:pfam17380 596 PITTIKPIYRPRIseyqpPDVES 618
 
Name Accession Description Interval E-value
JAKMIP_CC3 pfam16034
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
429-625 5.44e-93

JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.


Pssm-ID: 464986 [Multi-domain]  Cd Length: 199  Bit Score: 293.32  E-value: 5.44e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 429 ERDKLLRFRKQRKKMAKLPKP-VVVETFFGYDEEASLESDGSSVSYQTDRTDQTPCTPDDDLEEGMAKEETELRFRQLTM 507
Cdd:pfam16034   1 ERDKLIRARKQRRKEKKKKLRdMVVETFFGYDEEASVDSETSSLSYNTDRTDSTPATPDEDLDEGVAAEEAELRFRQLTR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 508 EYQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQALYRRNQELVEKIKQM 587
Cdd:pfam16034  81 EYQALQRAYALLQEQSGGTLDAEREAKTREQLQAELRRAQSRIEDLESALAQKGQDSKWVEEKQALIRRNQELVEKIRIM 160
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2217276844 588 ETEEARLRHEVQDARDQNELLEFRILELEERERKSPAI 625
Cdd:pfam16034 161 EQEEGRLKNEIQDARDQNELLEFRILELEERERRSPAI 198
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-830 1.28e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 1.28e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   27 DLRAKLTDIQIELQ--QEKSKVSKVEREKNQELRQVREHEQHKTAVLLTELKtklHEEKMKELQAVRETLLRQhEAELLR 104
Cdd:TIGR02168  217 ELKAELRELELALLvlRLEELREELEELQEELKEAEEELEELTAELQELEEK---LEELRLEVSELEEEIEEL-QKELYA 292
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  105 VIKIKDNENQRLQALLSALRDGGPEKVKTVLLSEAKEEAKKGFEVEKVKMQQEISELKGakrqveealtlVIQADKIKAA 184
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE-----------ELESLEAELE 361
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  185 EIRSVyhlhQEEITRIKKECEREIRRLmeeikfkDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREADRhpgspr 264
Cdd:TIGR02168  362 ELEAE----LEELESRLEELEEQLETL-------RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE------ 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  265 relphaagagdasdhsgSPEQQLDEKDARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRL 344
Cdd:TIGR02168  425 -----------------ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  345 SRKNEDLSHALRRMENKLKFVTQENIEMRQRAGIIRRPSSLNDLDqSQDEREVDflklqIVEQQNLIDELSKTLETAGYV 424
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIE-----AALGGRLQAVVVENLNAAKKA 561
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  425 KSVLERDKLLRfrkqrkkMAKLPKPVVVETFFGYDEEASLESDGSSVSYQTDRTDQTP------------CTPDDDLEEG 492
Cdd:TIGR02168  562 IAFLKQNELGR-------VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggVLVVDDLDNA 634
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  493 MA-KEETELRFRQLTMEYQALQRAYALLQ---EQVGGTLDAEREVktrEQLQAEVQRAQARIEDLEKALAE---QGQDMK 565
Cdd:TIGR02168  635 LElAKKLRPGYRIVTLDGDLVRPGGVITGgsaKTNSSILERRREI---EELEEKIEELEEKIAELEKALAElrkELEELE 711
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  566 wiEEKQALYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERERKSPAIsfhhtpfVDGKSPLQVYCEA 645
Cdd:TIGR02168  712 --EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER-------LEEAEEELAEAEA 782
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  646 EgvtdivVAELMKKLDILGDNANLTNEEQVvviQARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEE 725
Cdd:TIGR02168  783 E------IEELEAQIEQLKEELKALREALD---ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  726 LDYRKQALDQANKHILELEAMLYDALQQEAGAKVAELLSEEEREKLkvaveqwkrqvMSELRERDAQILRERmELLQLAQ 805
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL-----------SEELRELESKRSELR-RELEELR 921
                          810       820
                   ....*....|....*....|....*
gi 2217276844  806 QRIKELEERIEAQKRQIKELEEKLS 830
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLS 946
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
45-868 3.10e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.33  E-value: 3.10e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   45 KVSKVEREKNQELRQVREHEQHKTAVLltELKTKLHEEKMKELQAVRETLLRQHEAeLLRVIKIKDNENQRLQALLSALR 124
Cdd:TIGR02169  188 RLDLIIDEKRQQLERLRREREKAERYQ--ALLKEKREYEGYELLKEKEALERQKEA-IERQLASLEEELEKLTEEISELE 264
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  125 DGGPEKVKtvLLSEAKEEAKKGFEVEKVKMQQEISELKG----AKRQVEEALTLVIQADKiKAAEIRSVYHLHQEEITRI 200
Cdd:TIGR02169  265 KRLEEIEQ--LLEELNKKIKDLGEEEQLRVKEKIGELEAeiasLERSIAEKERELEDAEE-RLAKLEAEIDKLLAEIEEL 341
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  201 KKECEREIRR---LMEEIKFKDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREadrhpgsprrelphaagagDAS 277
Cdd:TIGR02169  342 EREIEEERKRrdkLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKR-------------------EIN 402
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  278 DHSGSPEQQLDEKdaRRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRLSRKNEDLSHALRR 357
Cdd:TIGR02169  403 ELKRELDRLQEEL--QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDR 480
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  358 MENKLKFVTQENIEMRQRAGIIRRPSSLNDLDQSQDEREVDFLKLQIVEQQNLIDELSKTLETAG-------YVKSVLER 430
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAgnrlnnvVVEDDAVA 560
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  431 DKLLRFRKQRK----------KMAKLPKPVVVETFFGYDEEAS--LESD---GSSVSYQTDRTDQTpctpdDDLEEGmak 495
Cdd:TIGR02169  561 KEAIELLKRRKagratflplnKMRDERRDLSILSEDGVIGFAVdlVEFDpkyEPAFKYVFGDTLVV-----EDIEAA--- 632
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  496 EETELRFRQLTMEYQALQRAYALlqeqVGGTLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEekQALYR 575
Cdd:TIGR02169  633 RRLMGKYRMVTLEGELFEKSGAM----TGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIE--NRLDE 706
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  576 RNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERERKSPAISFHHTPFVDGKSPLQVYCEA--EGVTDIVV 653
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKleEALNDLEA 786
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  654 AELMKKLDILGDNANLTNEEQVvviqartvltlaeKWLQQIEETEAALQRKMVD---LESEKELFSKQKGYLDEELDYRK 730
Cdd:TIGR02169  787 RLSHSRIPEIQAELSKLEEEVS-------------RIEARLREIEQKLNRLTLEkeyLEKEIQELQEQRIDLKEQIKSIE 853
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  731 QALDQANKHILELEAMLydalqQEAGAKVAELlsEEEREKLKVAVEQWKRQvMSELRERdaqiLRERMELLQLAQQRIKE 810
Cdd:TIGR02169  854 KEIENLNGKKEELEEEL-----EELEAALRDL--ESRLGDLKKERDELEAQ-LRELERK----IEELEAQIEKKRKRLSE 921
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217276844  811 LEERIEAQKRQIKELEEKLSFSGHSPSWHPDVPHIEsdpfppvgpESRDKMGRRVSIL 868
Cdd:TIGR02169  922 LKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQ---------AELQRVEEEIRAL 970
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
495-838 4.61e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 4.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 495 KEETELRFRQLTMEYQALQRAYALLQEQVG-GTLDAEREVKTREQLQAEVQRAQARIEDLEKALAE-QGQDMKWIEEKQA 572
Cdd:COG1196   220 EELKELEAELLLLKLRELEAELEELEAELEeLEAELEELEAELAELEAELEELRLELEELELELEEaQAEEYELLAELAR 299
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 573 LYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERErkspaisfhhtpfvdgksplqvyceaegvtdiv 652
Cdd:COG1196   300 LEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL--------------------------------- 346
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 653 vAELMKKLDilgdnanltnEEQVVVIQARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQA 732
Cdd:COG1196   347 -EEAEEELE----------EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 733 LDQANKHILELEAmlydALQQEAGAKVAELLSEEEREKLKVAVEQwkrqvmsELRERDAQILRERMELLQLAQQRIKELE 812
Cdd:COG1196   416 LERLEEELEELEE----ALAELEEEEEEEEEALEEAAEEEAELEE-------EEEALLELLAELLEEAALLEAALAELLE 484
                         330       340
                  ....*....|....*....|....*.
gi 2217276844 813 ERIEAQKRQIKELEEKLSFSGHSPSW 838
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGFLEGV 510
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-619 3.32e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 3.32e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  26 EDLRAKLTDIQIELQQEKSKVSKVEREKNQELRQVREHEQHKTAVLLTELKTKLHEEKmKELQAVRETlLRQHEAELLRV 105
Cdd:COG1196   223 KELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-LELEEAQAE-EYELLAELARL 300
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 106 IKIKDNENQRLQALLSALRDggpekvktvlLSEAKEEAKKGFEVEKVKMQQEISELKGAKRQVEEALTLVIQADKIKAAE 185
Cdd:COG1196   301 EQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 186 IRSvyhlhQEEITRIKKECEREIRRLMEEIKFKDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREADRhpgsprr 265
Cdd:COG1196   371 EAE-----LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE------- 438
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 266 elphaagagdasdhsgspEQQLDEKDARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRLS 345
Cdd:COG1196   439 ------------------EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 346 RKNEDLSHALRRMENKlkfvtqeniemRQRAGIIRRPSSLNDLDQSqdEREVDFLKLQIVEQQNLIDELSKTLETAGYVK 425
Cdd:COG1196   501 ADYEGFLEGVKAALLL-----------AGLRGLAGAVAVLIGVEAA--YEAALEAALAAALQNIVVEDDEVAAAAIEYLK 567
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 426 S-VLERDKLLRFRKQRKKMAKLPKPVVVETFFGYDEEASLESDGSSVSYQ-TDRTDQTPCTPDDDLEEGMAKEETELRFR 503
Cdd:COG1196   568 AaKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVlGDTLLGRTLVAARLEAALRRAVTLAGRLR 647
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 504 QLTMEYQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQALYRRNQELVEK 583
Cdd:COG1196   648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALE 727
                         570       580       590
                  ....*....|....*....|....*....|....*.
gi 2217276844 584 IKQMETEEARLRHEVQDARDQNELLEFRILELEERE 619
Cdd:COG1196   728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
488-830 1.44e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.54  E-value: 1.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 488 DLEEGMAKEETELRFRQLTMEYQALQRAYALLQEQVGgtlDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWI 567
Cdd:COG4717   113 ELREELEKLEKLLQLLPLYQELEALEAELAELPERLE---ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLA 189
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 568 EEKQA--LYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERERKS------PAISFHHTPFVDGKSPL 639
Cdd:COG4717   190 TEEELqdLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKearlllLIAAALLALLGLGGSLL 269
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 640 QVYCEAEGVTDIVVAELMKKLDILGDNANLTNEEQVVVIQARTVLTLAEKWLQQIeeteaaLQRKMVDLESEKELFSKQK 719
Cdd:COG4717   270 SLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEEL------LAALGLPPDLSPEELLELL 343
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 720 GYLDEELDYRKQALDQANKHILELEAMLYDALQQEAGAKVAELLSE-----EEREKLKVAVEQWKRQVMSELRER----D 790
Cdd:COG4717   344 DRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAaleqaEEYQELKEELEELEEQLEELLGELeellE 423
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 2217276844 791 AQILRERMELLQLAQQRIKELEERIEAQKRQIKELEEKLS 830
Cdd:COG4717   424 ALDEEELEEELEELEEELEELEEELEELREELAELEAELE 463
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
494-821 3.91e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 3.91e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 494 AKEETELRFRQLTMEYQALQRAYALLQEQVGG--------TLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDmk 565
Cdd:COG1196   268 ELEELRLELEELELELEEAQAEEYELLAELARleqdiarlEERRRELEERLEELEEELAELEEELEELEEELEELEEE-- 345
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 566 wIEEKQALYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERERKSPAisfhhtpfvdgksplqvycEA 645
Cdd:COG1196   346 -LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-------------------EL 405
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 646 EGVTDIVVAELMKKLDILGDNANLTNEEQVVVIQARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELfskqkgyLDEE 725
Cdd:COG1196   406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL-------LEAA 478
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 726 LDYRKQALDQANKHILELEAMLYDALQQEAGAKVAELLSEEEREKLKVAVEQWKrqvmsELRERDAQILRERMELLQLAQ 805
Cdd:COG1196   479 LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV-----EAAYEAALEAALAAALQNIVV 553
                         330
                  ....*....|....*.
gi 2217276844 806 QRIKELEERIEAQKRQ 821
Cdd:COG1196   554 EDDEVAAAAIEYLKAA 569
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-595 7.33e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 7.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  26 EDLRAKLTDIQIELQQEKSKVskveREKNQELRQVREHEQHKTAVLLTELKTKLHEEKMKELQAVRETLLRQHEAELLRV 105
Cdd:COG1196   256 EELEAELAELEAELEELRLEL----EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEE 331
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 106 IkikDNENQRLQALLSALRDGGPEKVKTVLLSEAKEEAKKGFEVEKVKMQQEISELKG----AKRQVEEALTLVIQADKI 181
Cdd:COG1196   332 L---EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEelleALRAAAELAAQLEELEEA 408
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 182 KAAEIRSVYHLHQEEITRIKKECEREIRRLMEEIKFKDRAVFVLERELGVQAGHAQRLQLQKE-ALDEQLSQVREADRHP 260
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEaALLEAALAELLEELAE 488
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 261 GSPRRELPHAAGAGDASDHSGSPEQQLDEKDARRFQLKI--------------AELSAIIRKLEDRNALLSEERNELLKR 326
Cdd:COG1196   489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAvligveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLKA 568
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 327 VREAESQYKPLLDKNKRLSRKNEDLSHALRRMENKLKFVTQENIEMRQRAGIIRRPSSLNDLDQSQDEREVDFLKLQIVE 406
Cdd:COG1196   569 AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 407 QQNLIDELSKTLETAGYVKSVLERDKLLRFRKQRKKMAKLpkpvvvetffgYDEEASLESDGSSVSYQTDRTDQtpctpD 486
Cdd:COG1196   649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL-----------AEEELELEEALLAEEEEERELAE-----A 712
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 487 DDLEEGMAKEETELRFRQLTMEYQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQARIEDLEK--ALAeqgqdm 564
Cdd:COG1196   713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPvnLLA------ 786
                         570       580       590
                  ....*....|....*....|....*....|.
gi 2217276844 565 kwIEEKQALYRRNQELVEKIKQMETEEARLR 595
Cdd:COG1196   787 --IEEYEELEERYDFLSEQREDLEEARETLE 815
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
158-829 1.15e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 158 ISELKGAKRQVEEALTLVIQADKIKAAEIRSVYHLHQEEITRIKK---ECEREIRRLMEEIKFKDRAVFVLERELGVQAG 234
Cdd:COG1196   202 LEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAeleELEAELEELEAELAELEAELEELRLELEELEL 281
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 235 HAQRLQLQKEALDEQLSQVREADRHpgspRRElphaagagdasdhsgspEQQLDEKDARRFQLKIAELSAIIRKLEDRNA 314
Cdd:COG1196   282 ELEEAQAEEYELLAELARLEQDIAR----LEE-----------------RRRELEERLEELEEELAELEEELEELEEELE 340
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 315 LLSEERNELLKRVREAESQykpLLDKNKRLSRKNEDLSHALRRMENKLKfvtQENIEMRQRAGIIRRPSSLNDLDQSQDE 394
Cdd:COG1196   341 ELEEELEEAEEELEEAEAE---LAEAEEALLEAEAELAEAEEELEELAE---ELLEALRAAAELAAQLEELEEAEEALLE 414
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 395 REVDFLKLQIVEQQNLIDELSKTLETAgyvksvlerdkllrfrkqrkkmaklpkpvvvetffgydeeaslesdgssvsyq 474
Cdd:COG1196   415 RLERLEEELEELEEALAELEEEEEEEE----------------------------------------------------- 441
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 475 tdrtdqtpctpDDDLEEGMAKEETELRFRQLTMEYQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQR-AQARIEDL 553
Cdd:COG1196   442 -----------EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAdYEGFLEGV 510
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 554 EKALAEQGQDMKWieekQALYRRNQELVEKIKQMETEEARLRHE--VQDARDQNELLEFRILELEERERKSPAISFHHTP 631
Cdd:COG1196   511 KAALLLAGLRGLA----GAVAVLIGVEAAYEAALEAALAAALQNivVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARA 586
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 632 FVDGKSPLQVYCEAEGVTDIVVAELMKKLDILGDNAnltneeqVVVIQARTVLTLAEKWLQQIEETEAALQRKMVDLESE 711
Cdd:COG1196   587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTL-------LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG 659
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 712 KELFSKQKGYLDEELDYRKQALDQANKHILELEAMLYDALQQEAGAKVAELLSEEEREKLKVAVEQwKRQVMSELRERDA 791
Cdd:COG1196   660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA-LEEQLEAEREELL 738
                         650       660       670
                  ....*....|....*....|....*....|....*...
gi 2217276844 792 QILRERMELLQLAQQRIKELEERIEAQKRQIKELEEKL 829
Cdd:COG1196   739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
528-828 2.14e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 2.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 528 DAEREVKTR-EQLQAEVQRA------QARIEDLEKALAeqGQDMKWIEEKQALYRRN-QELVEKIKQMETEEARLRHEVQ 599
Cdd:COG1196   193 DILGELERQlEPLERQAEKAeryrelKEELKELEAELL--LLKLRELEAELEELEAElEELEAELEELEAELAELEAELE 270
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 600 DARDQNELLEFRILELEERERKSpaisfhhtpfvdgksplqvyceaegvtdivvaelmkkldilgdNANLTNEEQVVVIQ 679
Cdd:COG1196   271 ELRLELEELELELEEAQAEEYEL-------------------------------------------LAELARLEQDIARL 307
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 680 ARTVLTLAEKwLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHILELEAMLYDALQQEAGAKV 759
Cdd:COG1196   308 EERRRELEER-LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217276844 760 AELLSEEEREKLKVAVEQWKRQVMSELRERDAQILRERMELLQLAQQRIKELEERIEAQKRQIKELEEK 828
Cdd:COG1196   387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455
PTZ00121 PTZ00121
MAEBL; Provisional
36-621 4.28e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 4.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   36 QIELQQEKSKVSKVER-EKNQELRQVREHEQHKTAVLLTELKTKLHEEKMKELQAVRETllRQHEAELLRVIKIKDNENQ 114
Cdd:PTZ00121  1177 KAEAARKAEEVRKAEElRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEA--KKDAEEAKKAEEERNNEEI 1254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  115 RlqallsALRDGGPEKVKTVLLSEAKEEAKKGFEVEKVKMQQEISELKGA--KRQVEEAltlviqadKIKAAEIRSVYHL 192
Cdd:PTZ00121  1255 R------KFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAeeKKKADEA--------KKKAEEAKKADEA 1320
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  193 hQEEITRIKKECErEIRRLMEEIKFKDRAVfvlERELGVQAGHAQRLQLQKEALDEQLSQVREADRHPGSPRRELPHAAG 272
Cdd:PTZ00121  1321 -KKKAEEAKKKAD-AAKKKAEEAKKAAEAA---KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE 1395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  273 AGDASDHSGSPEQQLDEKDARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRLSRKNEDLS 352
Cdd:PTZ00121  1396 AKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEA 1475
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  353 HALRRMENKLKFVTQENIEMRQRAGIIRRPSS----LNDLDQSQDEREVDflKLQIVEQQNLIDELSKTLEtagyVKSVL 428
Cdd:PTZ00121  1476 KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEakkkADEAKKAEEAKKAD--EAKKAEEAKKADEAKKAEE----KKKAD 1549
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  429 ERDKLLRFRKQRKKMAklpkpvvVETFFGYDEEASLESDGSSVSYQTDRTDQTPCTPDDDLEEGMAKEETElRFRQLTME 508
Cdd:PTZ00121  1550 ELKKAEELKKAEEKKK-------AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK-KAEEAKIK 1621
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  509 YQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQARIEDLEKALAE---QGQDMKWIEEK-----QALYRRNQEL 580
Cdd:PTZ00121  1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkKAEEAKKAEEDekkaaEALKKEAEEA 1701
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 2217276844  581 --VEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERERK 621
Cdd:PTZ00121  1702 kkAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744
PTZ00121 PTZ00121
MAEBL; Provisional
38-603 7.86e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 7.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   38 ELQQEKSKVSKVEREKNQELRQVRE-----HEQHKTAVLLTELKTKLHEEKMKELQAVRETLLRQHEAELLRVIKIKDNE 112
Cdd:PTZ00121  1234 EAKKDAEEAKKAEEERNNEEIRKFEearmaHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE 1313
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  113 NQRLQALLSALRDGgpeKVKTVLLSEAKEEAKKGFEVEKVKMQQEISELKGAKRQvEEALTLVIQADKIKAAEIRSvyhl 192
Cdd:PTZ00121  1314 AKKADEAKKKAEEA---KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-AEAAEKKKEEAKKKADAAKK---- 1385
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  193 HQEEITR---IKKECErEIRRLMEEIKFKDRAVFVLER-----ELGVQAGHAQRLQLQKEALDEQLSQVREADRHPGSPR 264
Cdd:PTZ00121  1386 KAEEKKKadeAKKKAE-EDKKKADELKKAAAAKKKADEakkkaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  265 RelPHAAGAGDASDHSGSPEQQLDE--KDARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNK 342
Cdd:PTZ00121  1465 K--AEEAKKADEAKKKAEEAKKADEakKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKA 1542
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  343 RLSRKNEDLSHA--LRRMENKLKfVTQENIEMRQRAGIIRRPSslnDLDQSQDEREVDFLKLQIVEQQNLIDELSKTLEt 420
Cdd:PTZ00121  1543 EEKKKADELKKAeeLKKAEEKKK-AEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE- 1617
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  421 agyvksvlERDKLLRFRKQ---RKKMAKLPKPVVVETffGYDEEASLESDGSSVSYQTDRTDQTPctpDDDLEEGMAKEE 497
Cdd:PTZ00121  1618 --------AKIKAEELKKAeeeKKKVEQLKKKEAEEK--KKAEELKKAEEENKIKAAEEAKKAEE---DKKKAEEAKKAE 1684
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  498 TELRFRQLTMEYQALQRAYAllqEQVggTLDAEREVKTREQLQAEVQRAQARIEDLEKalaEQGQDMKWIEEkqalYRRN 577
Cdd:PTZ00121  1685 EDEKKAAEALKKEAEEAKKA---EEL--KKKEAEEKKKAEELKKAEEENKIKAEEAKK---EAEEDKKKAEE----AKKD 1752
                          570       580
                   ....*....|....*....|....*.
gi 2217276844  578 QELVEKIKQMETEEARLRHEVQDARD 603
Cdd:PTZ00121  1753 EEEKKKIAHLKKEEEKKAEEIRKEKE 1778
PTZ00121 PTZ00121
MAEBL; Provisional
82-828 2.44e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 2.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   82 EKMKELQAVRETLLRQHEAELLRVIKIKDnENQRLQALLSALRDGGPEKVKTVLLSEAKEEAKKGFEVEKVKMQQEISEL 161
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEE-ARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDA 1163
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  162 KGAK--RQVEEALTlvIQADKiKAAEIRSVYHLHQEEITRIKKECER--EIRRLMEEIKFKD-RAVFVLERELGVQAGHA 236
Cdd:PTZ00121  1164 RKAEeaRKAEDAKK--AEAAR-KAEEVRKAEELRKAEDARKAEAARKaeEERKAEEARKAEDaKKAEAVKKAEEAKKDAE 1240
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  237 QRLQLQKEALDEQLSQVREAdRHPGSPRRELPHAAGAGDASDHSGSPEQQLDEKDARRFQLKIAELSAIIRKLEDRNA-L 315
Cdd:PTZ00121  1241 EAKKAEEERNNEEIRKFEEA-RMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAdE 1319
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  316 LSEERNELLKRVREAESQYKPLLDKNKRLSRKNEDLSHALRRMENKLKFVTQENIEMRQRAGIIRRpsslndldQSQDER 395
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK--------KAEEKK 1391
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  396 EVDFLKLQIVEQQNLIDELSKTLETAGYVKSVLERDKLLRFRKQRKKMAKLPKPVvvetffgydEEASLESDGSSVSyqt 475
Cdd:PTZ00121  1392 KADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA---------DEAKKKAEEAKKA--- 1459
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  476 drtdqtpctpdddlEEGMAKEETELRFRQLTMEYQALQRAYALLQEqvggtldAEREVKTREQLQaEVQRAQARIEDLEK 555
Cdd:PTZ00121  1460 --------------EEAKKKAEEAKKADEAKKKAEEAKKADEAKKK-------AEEAKKKADEAK-KAAEAKKKADEAKK 1517
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  556 AL-AEQGQDMKWIEEKqalyRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRilelEERERKSPAI-SFHHTPFV 633
Cdd:PTZ00121  1518 AEeAKKADEAKKAEEA----KKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK----KAEEDKNMALrKAEEAKKA 1589
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  634 DGKSPLQVYCEAEGVTDIVVAELMKKLDILGDNANLTNEEQVvviqartvltlaEKWLQQIEETEAALQRKMVDLESEKE 713
Cdd:PTZ00121  1590 EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE------------KKKVEQLKKKEAEEKKKAEELKKAEE 1657
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  714 LFSKQKGYLDEELDYRKQALDQANKhileleamlydalQQEAGAKVAELLSEEEREKLKVavEQWKRQVMSELRERDAQI 793
Cdd:PTZ00121  1658 ENKIKAAEEAKKAEEDKKKAEEAKK-------------AEEDEKKAAEALKKEAEEAKKA--EELKKKEAEEKKKAEELK 1722
                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2217276844  794 LRERMELLQLAQQRIKELEERIEAQKRQIKELEEK 828
Cdd:PTZ00121  1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
521-830 3.66e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.76  E-value: 3.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  521 EQVGGTLDAEREvktREQLQAEVQRAQARIEDLEKALAEQGQDMKWI-------EEKQALYRRNQE-----LVEKIKQME 588
Cdd:TIGR02169  160 DEIAGVAEFDRK---KEKALEELEEVEENIERLDLIIDEKRQQLERLrrerekaERYQALLKEKREyegyeLLKEKEALE 236
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  589 TEEARLRHEVQDARDQNELLEFRILELEERerkspaisfhhtpfvdgksplqvYCEAEgvtdIVVAELMKKLDILGDNAN 668
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKR-----------------------LEEIE----QLLEELNKKIKDLGEEEQ 289
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  669 LTNEEQVVVI-----QARTVLTLAEKWLQQIEETEA-------ALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQA 736
Cdd:TIGR02169  290 LRVKEKIGELeaeiaSLERSIAEKERELEDAEERLAkleaeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDL 369
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  737 NKHILELEAmlydalqqEAGAKVAELLSEEER-EKLKVAVEQWKR---QVMSELRERDAQILRERMELlQLAQQRIKELE 812
Cdd:TIGR02169  370 RAELEEVDK--------EFAETRDELKDYREKlEKLKREINELKReldRLQEELQRLSEELADLNAAI-AGIEAKINELE 440
                          330
                   ....*....|....*...
gi 2217276844  813 ERIEAQKRQIKELEEKLS 830
Cdd:TIGR02169  441 EEKEDKALEIKKQEWKLE 458
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
26-256 4.87e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 4.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  26 EDLRAKLTDIQIELQQEKSKVSKVEREKNQELRQVREHEQhktAVLLTELKTKLHEEKMKELQAVretlLRQHEAELLRV 105
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER---RIAALARRIRALEQELAALEAE----LAELEKEIAEL 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 106 IKIKDNENQRLQALLSAL-RDGGPEKVKTVLLSEAKEEAkkgfevekVKMQQEISELKGAKRQVEEALTLVIQADKIKAA 184
Cdd:COG4942    96 RAELEAQKEELAELLRALyRLGRQPPLALLLSPEDFLDA--------VRRLQYLKYLAPARREQAEELRADLAELAALRA 167
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217276844 185 EIRSvyhlHQEEITRIKKECEREIRRLMEEIKFKDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREA 256
Cdd:COG4942   168 ELEA----ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
227-620 2.45e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 2.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 227 RELGVQAGHAQRLQLQKEALDEQLSQVREADRHPGSPRRELPHAAGAGDASDHSGSPEQQLDEKDAR--RFQLKIAELSA 304
Cdd:COG4717    81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERleELEERLEELRE 160
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 305 IIRKLEDRNALLSEERNELLKRVREAESQYKPLLdknKRLSRKNEDLSHALRRMENKLKFVTQENIEMRQRAGIIRRPSS 384
Cdd:COG4717   161 LEEELEELEAELAELQEELEELLEQLSLATEEEL---QDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELE 237
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 385 LNDLDQSQDEREVDFLKLQIVE--QQNLIDELSKTLETAGYVKSVLERDKLLRFRKQRKKMAKLPKPVVVETFFGYD--E 460
Cdd:COG4717   238 AAALEERLKEARLLLLIAAALLalLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEelE 317
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 461 EASLESDGSSVSYQTDRTDQTPCTPDDDLEEgMAKEETELRFRQLTMEYQALQRAYALLQEQVGGTLDAE-----REVKT 535
Cdd:COG4717   318 EEELEELLAALGLPPDLSPEELLELLDRIEE-LQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEElraalEQAEE 396
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 536 REQLQAEVQRAQARIEDLEK---ALAEQGQDMKWIEEKQALYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRI 612
Cdd:COG4717   397 YQELKEELEELEEQLEELLGeleELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ 476

                  ....*...
gi 2217276844 613 LELEERER 620
Cdd:COG4717   477 ELEELKAE 484
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
679-835 3.38e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 3.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  679 QARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHILELEAMLYDALQQEAGAK 758
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  759 VAELLSEEEREKLKVAVEQWKRQVM---SELRERDAQILRERMELLQLA------QQRIKELEERIEAQKRQIKELEEKL 829
Cdd:TIGR02168  775 EELAEAEAEIEELEAQIEQLKEELKalrEALDELRAELTLLNEEAANLRerleslERRIAATERRLEDLEEQIEELSEDI 854

                   ....*.
gi 2217276844  830 SFSGHS 835
Cdd:TIGR02168  855 ESLAAE 860
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
534-774 3.76e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 3.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 534 KTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEK-QALYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRI 612
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQlAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 613 LELEERERKSPAISFHHtpfvDGKSPLQVYCEAEGVTDIV-VAELMKKLdilgdnaNLTNEEQVVVIQARtvltlaekwL 691
Cdd:COG4942   100 EAQKEELAELLRALYRL----GRQPPLALLLSPEDFLDAVrRLQYLKYL-------APARREQAEELRAD---------L 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 692 QQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHILELEAMLYDALQQEA--GAKVAELLSEEERE 769
Cdd:COG4942   160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEelEALIARLEAEAAAA 239

                  ....*
gi 2217276844 770 KLKVA 774
Cdd:COG4942   240 AERTP 244
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
692-828 4.21e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 4.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 692 QQIEETEAALQR-----KMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHILELEAML-----------YDALQQEA 755
Cdd:COG3206   189 KELEEAEAALEEfrqknGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLgsgpdalpellQSPVIQQL 268
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 756 GAKVAELLSEEEREKLK--------VAVEQWKRQVMSELRERDAQILRERMELLQLAQQRIKELEERIEAQKRQIKELEE 827
Cdd:COG3206   269 RAQLAELEAELAELSARytpnhpdvIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPE 348

                  .
gi 2217276844 828 K 828
Cdd:COG3206   349 L 349
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
496-620 5.11e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 5.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  496 EETELRFRQLTMEYQALQRAYALLQEQvggtLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWI----EEKQ 571
Cdd:COG4913    620 AELEEELAEAEERLEALEAELDALQER----REALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLaaleEQLE 695
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 2217276844  572 ALYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERER 620
Cdd:COG4913    696 ELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR 744
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
531-847 9.87e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 9.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 531 REVKTREQL-------QAEVQRAQARIEDLEKALAEQGQDMKWI---EEKQALYR-RNQELVEKIKQM-ETEEARLRHEV 598
Cdd:pfam17380 310 REVERRRKLeeaekarQAEMDRQAAIYAEQERMAMERERELERIrqeERKRELERiRQEEIAMEISRMrELERLQMERQQ 389
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 599 QDARDQNELLEFRILELEERERKspaisfhhtpfvdgKSPLQVYCEAEGVTdivvaelmkkldilgdnanlTNEEQVVVI 678
Cdd:pfam17380 390 KNERVRQELEAARKVKILEEERQ--------------RKIQQQKVEMEQIR--------------------AEQEEARQR 435
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 679 QARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHI-LELEAMLYDALQQEAGA 757
Cdd:pfam17380 436 EVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILeKELEERKQAMIEEERKR 515
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 758 KVAELLSE-------EEREKLKVAVEQWKRQVMSELRERDAQILRERMELLQL-AQQRIKELEERIEAQKRQIKELEEKL 829
Cdd:pfam17380 516 KLLEKEMEerqkaiyEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLeAMEREREMMRQIVESEKARAEYEATT 595
                         330       340
                  ....*....|....*....|...
gi 2217276844 830 SFSGHSPSWHPDV-----PHIES 847
Cdd:pfam17380 596 PITTIKPIYRPRIseyqpPDVES 618
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
205-595 1.16e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  205 EREIRRLMEEIKFKDRAVFVLERELgvqaghaQRLQLQKEALDEQLSQVREAdrhpgspRRELPHAAGAGDASDHSGSPE 284
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKAL-------AELRKELEELEEELEQLRKE-------LEELSRQISALRKDLARLEAE 741
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  285 QQLDEKDARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRLSRKNEDLSHALRRMENKLKF 364
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  365 VTQENIEMRQRAGIIRRpsSLNDLDQSQDEREVD--FLKLQIVEQQNLIDELSKTLETAGYVKSVLERDKLLRFRKQRKK 442
Cdd:TIGR02168  822 LRERLESLERRIAATER--RLEDLEEQIEELSEDieSLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL 899
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  443 MAKLPKpvvVETFFGYDEEASLESDGSSVSYQtdrtdqtpctpdddleegMAKEETELRFRQLTmeyQALQRAYALLQEq 522
Cdd:TIGR02168  900 SEELRE---LESKRSELRRELEELREKLAQLE------------------LRLEGLEVRIDNLQ---ERLSEEYSLTLE- 954
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217276844  523 vggtlDAEREVKTREqlqAEVQRAQARIEDLEKALAEQGQ-DMKWIEEKQALYRRNQELVEKIKQMETEEARLR 595
Cdd:TIGR02168  955 -----EAEALENKIE---DDEEEARRRLKRLENKIKELGPvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLE 1020
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
138-830 1.50e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  138 EAKEEAKKGFEVEKVKMQQEISELKGAKRQVEealtlviqadKIKAAEIRSVYHLHQEEITRIKKECEREIRRLMEEIKF 217
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQEL----------KLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  218 KDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREADRhpgsprrelphaagagdasdhsgspEQQLDEKDARRFQL 297
Cdd:pfam02463  239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK-------------------------EKKLQEEELKLLAK 293
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  298 KIAELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRLSRKNEDLSHALRRMENKLKFVTQENIEMRQRAG 377
Cdd:pfam02463  294 EEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEE 373
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  378 IIRRPSSLNDLDQSQDEREVDFLKLQIVEQQNLIDELSKTLETAGYVKSVLERDKLLRFRKQRKKMAKLPKPVVVETFFG 457
Cdd:pfam02463  374 ELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEEL 453
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  458 YDEEASLESDGSSVSYQTDRTDQTPCTPD----DDLEEGMAKEETELRFRQLTMEYQALQrayALLQEQVGGTLDAEREV 533
Cdd:pfam02463  454 EKQELKLLKDELELKKSEDLLKETQLVKLqeqlELLLSRQKLEERSQKESKARSGLKVLL---ALIKDGVGGRIISAHGR 530
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  534 KTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQALYRRNQELVEKIKQMETEEARLRHevqDARDQNELLEFRIL 613
Cdd:pfam02463  531 LGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS---IAVLEIDPILNLAQ 607
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  614 ELEERERKSPAISFHHTPFVDGKSPLQVYcEAEGVTDIVVAELMKKLDILGDNANLTNEEQVVVIQARTVLTLAEKWLQQ 693
Cdd:pfam02463  608 LDKATLEADEDDKRAKVVEGILKDTELTK-LKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAE 686
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  694 IEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHILELEamlYDALQQEAGAKVAELLSEEEREKLKV 773
Cdd:pfam02463  687 SELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEE---LKLLKQKIDEEEEEEEKSRLKKEEKE 763
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217276844  774 AVEQWKRQVMSELRERDAQILRERMELLQLAQQRIKELEERIEAQKRQIKELEEKLS 830
Cdd:pfam02463  764 EEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEE 820
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
26-600 1.58e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 1.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  26 EDLRAKLTDIQIELQQEKSKVSKVErEKNQELRQVREHeqhktavllTELKTKLHEEKMKELQAVRETLLRQHE-AELLR 104
Cdd:PRK03918  234 EELKEEIEELEKELESLEGSKRKLE-EKIRELEERIEE---------LKKEIEELEEKVKELKELKEKAEEYIKlSEFYE 303
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 105 VIKIKDNENQRLQALLSALRDGGPEKVKTVllsEAKEEAKKGFEVEKVKMQQEISELKGAKRQVEEALTLVIQADKIKaa 184
Cdd:PRK03918  304 EYLDELREIEKRLSRLEEEINGIEERIKEL---EEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLK-- 378
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 185 eirsvyhlhqeeitriKKECEREIRRLMEEIKFKDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREADRHPGSPR 264
Cdd:PRK03918  379 ----------------KRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCG 442
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 265 RELphaagagdasdhsgspeqqlDEKDARRFqlkIAELSAIIRKLEDRNALLSEERNELLKRVREAESqykpLLDKNKRL 344
Cdd:PRK03918  443 REL--------------------TEEHRKEL---LEEYTAELKRIEKELKEIEEKERKLRKELRELEK----VLKKESEL 495
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 345 SrKNEDLSHALRRMENKLKFVTQENIEMRQR-AGIIRRPSSLNDLDQSQDEREVDFLKLQIVEQQNLIDELSKTLETAGY 423
Cdd:PRK03918  496 I-KLKELAEQLKELEEKLKKYNLEELEKKAEeYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAE 574
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 424 VKSVLERDKLLRFRKQRKKMAKLPKPvvvetffgYDEEASLESDGSSVSYQTDRTDQTPCTPDDDLEEgmaKEETELRFR 503
Cdd:PRK03918  575 LLKELEELGFESVEELEERLKELEPF--------YNEYLELKDAEKELEREEKELKKLEEELDKAFEE---LAETEKRLE 643
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 504 QLTMEYQALQRAYAllQEqvggtlDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQALYRRNQELVEK 583
Cdd:PRK03918  644 ELRKELEELEKKYS--EE------EYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEK 715
                         570
                  ....*....|....*..
gi 2217276844 584 IKQMETEEARLRHEVQD 600
Cdd:PRK03918  716 LEKALERVEELREKVKK 732
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
528-617 1.59e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.15  E-value: 1.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 528 DAEREVKTRE--QLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQALYRRNQELV----EKIKQMETEEARLRHEVQDA 601
Cdd:COG2433   405 ERELTEEEEEirRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREirkdREISRLDREIERLERELEEE 484
                          90
                  ....*....|....*.
gi 2217276844 602 RDQNELLEFRILELEE 617
Cdd:COG2433   485 RERIEELKRKLERLKE 500
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
26-256 1.68e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 1.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   26 EDLRAKLTDIQIELQQEKSKVSKVEREKNQELRQVREHEQHKTAVLL----TELKTKLHEEKMKELQAVRETLLRQHEA- 100
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEErleeAEEELAEAEAEIEELEAQIEQLKEELKAl 801
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  101 --ELLRVIKIKDNENQRLQALLSALRDGGPEKVKTVLLSEAKEEAKKGFEVEKVKMQQEISELKGAKRQVEEALTlviQA 178
Cdd:TIGR02168  802 reALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE---AL 878
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217276844  179 DKIKAAeirsvyhlHQEEITRIKKECEreirRLMEEIKFKDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREA 256
Cdd:TIGR02168  879 LNERAS--------LEEALALLRSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
PTZ00121 PTZ00121
MAEBL; Provisional
38-219 1.71e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   38 ELQQEKSKVSKVEREKNQELRQVREHEQHKTA-----VLLTELKTKLHEEKMKELQAVRETLLRQHEAELLrviKIKDNE 112
Cdd:PTZ00121  1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAeeenkIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEAL---KKEAEE 1700
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  113 NQRLQALlsalRDGGPEKVKTVllseakEEAKKGFEVEKVKMQQEISELKGAKRQVEEALtlVIQADKIKAAEIRSVYHL 192
Cdd:PTZ00121  1701 AKKAEEL----KKKEAEEKKKA------EELKKAEEENKIKAEEAKKEAEEDKKKAEEAK--KDEEEKKKIAHLKKEEEK 1768
                          170       180       190
                   ....*....|....*....|....*....|....
gi 2217276844  193 HQEEITRIKKEC-------EREIRRLMEEIKFKD 219
Cdd:PTZ00121  1769 KAEEIRKEKEAVieeeldeEDEKRRMEVDKKIKD 1802
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
679-829 2.27e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 2.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 679 QARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHILELEAMLyDALQQEAGAK 758
Cdd:COG4942    31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL-EAQKEELAEL 109
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217276844 759 VAEL--LSEEEREKLKVAVEQWKRQV-MSELRERDAQILRERMELLQLAQQRIKELEERIEAQKRQIKELEEKL 829
Cdd:COG4942   110 LRALyrLGRQPPLALLLSPEDFLDAVrRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
655-829 2.36e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.84  E-value: 2.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 655 ELMKKLDILGDNANLTN-----EEQVVVIQARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQK------GYLD 723
Cdd:PRK05771   54 KLSEALDKLRSYLPKLNplreeKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIerlepwGNFD 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 724 EELDYrkqALDQANKHIL--ELEAMLYDALQQEAGAKVAELLSEEEREKLKVAVeqwkrqVMSELRERDAQILR----ER 797
Cdd:PRK05771  134 LDLSL---LLGFKYVSVFvgTVPEDKLEELKLESDVENVEYISTDKGYVYVVVV------VLKELSDEVEEELKklgfER 204
                         170       180       190
                  ....*....|....*....|....*....|....
gi 2217276844 798 MELLQ--LAQQRIKELEERIEAQKRQIKELEEKL 829
Cdd:PRK05771  205 LELEEegTPSELIREIKEELEEIEKERESLLEEL 238
PRK09039 PRK09039
peptidoglycan -binding protein;
721-832 2.38e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.49  E-value: 2.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 721 YLDEELDYRKQALDQANKHILELEAMLydALQQEA----GAKVAEL-----LSEEEREKLKVAVEQWKRQvMSELRERDA 791
Cdd:PRK09039   43 FLSREISGKDSALDRLNSQIAELADLL--SLERQGnqdlQDSVANLraslsAAEAERSRLQALLAELAGA-GAAAEGRAG 119
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2217276844 792 QI---LRERMELLQLAQQRIKELEERIEAQKRQIKELEEKLSFS 832
Cdd:PRK09039  120 ELaqeLDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDAS 163
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
534-618 3.09e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 3.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844 534 KTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQALYRRNQELVEKIKQMETeearLRHEVQDARDQNELLEFRIL 613
Cdd:COG1579    38 DELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEA----LQKEIESLKRRISDLEDEIL 113

                  ....*
gi 2217276844 614 ELEER 618
Cdd:COG1579   114 ELMER 118
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
138-335 3.11e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 3.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  138 EAKEEAKKGFEVEKVKMQQEISELKGAKRQVEEALTLVIQADKIKAAEIRSVYHlhQEEITRIKKECER------EIRRL 211
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASA--EREIAELEAELERldassdDLAAL 690
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  212 MEEIKFKDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREADRHPGSPRRELPHAAGagdasdhsgspeqqldekD 291
Cdd:COG4913    691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL------------------E 752
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2217276844  292 ARRFQLKIAELSAIIRK-LEDRNALLSEERNELLKRVREAESQYK 335
Cdd:COG4913    753 ERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFN 797
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
670-842 3.44e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 3.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  670 TNEEQVVVIQARtvLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDY------------RKQALDQAN 737
Cdd:COG4913    607 DNRAKLAALEAE--LAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVasaereiaeleaELERLDASS 684
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  738 KHILELEAMLYDALQQEAGAKVAELLSEEEREKLKVAVEQWKRQVMSELRERDAQILRERMELLQLAQQRIKE------- 810
Cdd:COG4913    685 DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAalgdave 764
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2217276844  811 ------LEERIEAQKRQIKELEEKL--SFSGHSPSWHPDV 842
Cdd:COG4913    765 relrenLEERIDALRARLNRAEEELerAMRAFNREWPAET 804
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
25-226 3.67e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.58  E-value: 3.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   25 NEDLRAKLTDIQIELQQEKSKVSKVEREKNQELRQVREHEQHKTAVLLTELKTKLHEEKMKELQAVRETlLRQHEAELLR 104
Cdd:TIGR01612  691 NTEDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKDLNKILED-FKNKEKELSN 769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  105 VIKIKDNENQRLQALLSALRDGGPEKVKTVLLSEAK-EEAKKGFE----------VEKVKMQQEISELKGAKRQVEEALT 173
Cdd:TIGR01612  770 KINDYAKEKDELNKYKSKISEIKNHYNDQINIDNIKdEDAKQNYDkskeyiktisIKEDEIFKIINEMKFMKDDFLNKVD 849
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2217276844  174 LVIQADKIKAAEIRSVYHLHQEEITRIKKECEREIRRLMEEiKFKDRAVFVLE 226
Cdd:TIGR01612  850 KFINFENNCKEKIDSEHEQFAELTNKIKAEISDDKLNDYEK-KFNDSKSLINE 901
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
236-595 5.16e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.82  E-value: 5.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  236 AQRLQLQKEALDEQLSQVREADRHPGSPRRELPHAAGAGDASDHSGSPEQQLDEKDARRFQLKIAELSAIIRKLEDRNAL 315
Cdd:TIGR02169  676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN 755
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  316 LSEERNELLKRVREAESQYKPLLDKNKRLSRKneDLSHALRRMENKLKFVTQENIEMRQRAGIIRRPSSLNDLDQSQDER 395
Cdd:TIGR02169  756 VKSELKELEARIEELEEDLHKLEEALNDLEAR--LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK 833
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  396 EVDFLKLQIVEQQNLIDELSKTLEtagyvksvlerdkLLRFRKqRKKMAKLPKPVVvetffgydEEASLESDGSSVSYQT 475
Cdd:TIGR02169  834 EIQELQEQRIDLKEQIKSIEKEIE-------------NLNGKK-EELEEELEELEA--------ALRDLESRLGDLKKER 891
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  476 DRTDQTPCTPDDDLEEGMAK-EETELRFRQLTMEYQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQARIEDLE 554
Cdd:TIGR02169  892 DELEAQLRELERKIEELEAQiEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALE 971
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 2217276844  555 KAlaeqgqDMKWIEEKQALYRRNQELVEKIKQMETEEARLR 595
Cdd:TIGR02169  972 PV------NMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
691-829 6.50e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 6.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  691 LQQIEETEAAL-----QRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHILELEAmlydALQQEAGAKVAELlsE 765
Cdd:COG4913    271 LAELEYLRAALrlwfaQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEA----QIRGNGGDRLEQL--E 344
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  766 EEREKLKVAVEQWKR--------------------QVMSELRERDAQILRERMELLQLAQQRIKELEERIEAQKRQIKEL 825
Cdd:COG4913    345 REIERLERELEERERrrarleallaalglplpasaEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL 424

                   ....
gi 2217276844  826 EEKL 829
Cdd:COG4913    425 EAEI 428
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
27-363 7.66e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 40.10  E-value: 7.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   27 DLRAKLTDIQIELQQEK----SKVSKVERE---KNQELRQVR------EHEQHKTAVLLTELKTKLHEEKmKELQAVRET 93
Cdd:pfam15921  321 DLESTVSQLRSELREAKrmyeDKIEELEKQlvlANSELTEARterdqfSQESGNLDDQLQKLLADLHKRE-KELSLEKEQ 399
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844   94 LLRQHEAE---------LLRVIKIKDNENQRLQALLSALRdggpekvktvllSEAKEEakkgfevekvkMQQEISELKGA 164
Cdd:pfam15921  400 NKRLWDRDtgnsitidhLRRELDDRNMEVQRLEALLKAMK------------SECQGQ-----------MERQMAAIQGK 456
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  165 KRQVEEALTLVIQADKIKAAEIRSVYHLHQEEITRikKECEREIRRLMEEIKFKDRAVFVLERE---------------- 228
Cdd:pfam15921  457 NESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTL--ESSERTVSDLTASLQEKERAIEATNAEitklrsrvdlklqelq 534
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  229 -LGVQAGHAQRLQLQKEALDEQLS---QVREADRHPGSPRREL--PHAAGAGDASDHSGSPEQQLDEkdaRRFQL----- 297
Cdd:pfam15921  535 hLKNEGDHLRNVQTECEALKLQMAekdKVIEILRQQIENMTQLvgQHGRTAGAMQVEKAQLEKEIND---RRLELqefki 611
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  298 -------KIAELSAIIRKLEDRNALL--------------SEERNELLKRVREAESQYKPLLDKNKRLSRKNEDLSHALR 356
Cdd:pfam15921  612 lkdkkdaKIRELEARVSDLELEKVKLvnagserlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEME 691

                   ....*..
gi 2217276844  357 RMENKLK 363
Cdd:pfam15921  692 TTTNKLK 698
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
494-621 8.46e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.28  E-value: 8.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217276844  494 AKEETELRFRQLTMEYQALQRAYAllqeQVGGtldaerevKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQAL 573
Cdd:COG4913    310 ELERLEARLDALREELDELEAQIR----GNGG--------DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPA 377
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 2217276844  574 YRRN-QELVEKIKQMETEEARLRHEVQDARDQnelLEFRILELEERERK 621
Cdd:COG4913    378 SAEEfAALRAEAAALLEALEEELEALEEALAE---AEAALRDLRRELRE 423
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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