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Conserved domains on  [gi|2217283344|ref|XP_047283073|]
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protein Hikeshi isoform X3 [Homo sapiens]

Protein Classification

OPI10 family protein( domain architecture ID 8177)

overproducer of inositol protein 10 (OPI10) family protein is a DUF775 domain-containing protein similar to vertebrate protein Hikeshi and protein OPI10 from yeast and insects

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF775 super family cl05265
Protein of unknown function (DUF775); This family consists of several eukaryotic proteins of ...
 3-107 3.83e-28

Protein of unknown function (DUF775); This family consists of several eukaryotic proteins of unknown function.


The actual alignment was detected with superfamily member pfam05603:

Pssm-ID: 461690  Cd Length: 199  Bit Score: 101.10  E-value: 3.83e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217283344   3 EGSQHPFGAMNIVrTPSVAQIGISVELLDSMAQQTPVGNAAVSSVDS---------FTQFTQKMLDNFYNFASSFAVSQa 73
Cdd:pfam05603  91 SDNDSMFGASSPG-NSSTAQIGISIEPLEQVAQQLAALKASQSASSSsaassappsTKVLAQKIIKNAFNYLASFSGSQ- 168

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2217283344  74 qmtPSPSEMFIPANVVLKWYENFQRRLAQNPLFW 107
Cdd:pfam05603 169 ---PGGGEEVVPLKAFQDWWEKFERKLANDPNFL 199
 
Name Accession Description Interval E-value
DUF775 pfam05603
Protein of unknown function (DUF775); This family consists of several eukaryotic proteins of ...
 3-107 3.83e-28

Protein of unknown function (DUF775); This family consists of several eukaryotic proteins of unknown function.


Pssm-ID: 461690  Cd Length: 199  Bit Score: 101.10  E-value: 3.83e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217283344   3 EGSQHPFGAMNIVrTPSVAQIGISVELLDSMAQQTPVGNAAVSSVDS---------FTQFTQKMLDNFYNFASSFAVSQa 73
Cdd:pfam05603  91 SDNDSMFGASSPG-NSSTAQIGISIEPLEQVAQQLAALKASQSASSSsaassappsTKVLAQKIIKNAFNYLASFSGSQ- 168

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2217283344  74 qmtPSPSEMFIPANVVLKWYENFQRRLAQNPLFW 107
Cdd:pfam05603 169 ---PGGGEEVVPLKAFQDWWEKFERKLANDPNFL 199
PHA01633 PHA01633
putative glycosyl transferase group 1
 9-58 7.76e-03

putative glycosyl transferase group 1


Pssm-ID: 107050 [Multi-domain]  Cd Length: 335  Bit Score: 34.18  E-value: 7.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2217283344   9 FGAMNIVRTPSVAQiGISVELLDSMAQQTPVGNAAVSSVDSFTQFTQKML 58
Cdd:PHA01633  221 YGAMDFTIVPSGTE-GFGMPVLESMAMGTPVIHQLMPPLDEFTSWQWNLL 269
 
Name Accession Description Interval E-value
DUF775 pfam05603
Protein of unknown function (DUF775); This family consists of several eukaryotic proteins of ...
 3-107 3.83e-28

Protein of unknown function (DUF775); This family consists of several eukaryotic proteins of unknown function.


Pssm-ID: 461690  Cd Length: 199  Bit Score: 101.10  E-value: 3.83e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217283344   3 EGSQHPFGAMNIVrTPSVAQIGISVELLDSMAQQTPVGNAAVSSVDS---------FTQFTQKMLDNFYNFASSFAVSQa 73
Cdd:pfam05603  91 SDNDSMFGASSPG-NSSTAQIGISIEPLEQVAQQLAALKASQSASSSsaassappsTKVLAQKIIKNAFNYLASFSGSQ- 168

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2217283344  74 qmtPSPSEMFIPANVVLKWYENFQRRLAQNPLFW 107
Cdd:pfam05603 169 ---PGGGEEVVPLKAFQDWWEKFERKLANDPNFL 199
PHA01633 PHA01633
putative glycosyl transferase group 1
 9-58 7.76e-03

putative glycosyl transferase group 1


Pssm-ID: 107050 [Multi-domain]  Cd Length: 335  Bit Score: 34.18  E-value: 7.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2217283344   9 FGAMNIVRTPSVAQiGISVELLDSMAQQTPVGNAAVSSVDSFTQFTQKML 58
Cdd:PHA01633  221 YGAMDFTIVPSGTE-GFGMPVLESMAMGTPVIHQLMPPLDEFTSWQWNLL 269
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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