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Conserved domains on  [gi|2217291011|ref|XP_047285487|]
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SOSS complex subunit B1 isoform X1 [Homo sapiens]

Protein Classification

SOSS complex subunit B family protein( domain architecture ID 10139587)

SOSS complex subunit B family protein that contains an OB-fold nucleic acid binding domain; such as human SOSS complex subunit B2 (SSB2/NABP1), a component of the SOSS multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint

Gene Ontology:  GO:0006281|GO:0005634|GO:0070876|GO:0003697
PubMed:  19683501|19683490

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SoSSB_OBF cd04491
SoSSB_OBF: A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus ...
 43-120 1.64e-20

SoSSB_OBF: A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In vitro, SSoSSB can substitute for the basal transcription factor TBP, stimulating transcription from promoters under conditions in which TBP is limiting, and supporting transcription when TBP is absent. SSoSSB selectively melts the duplex DNA of promoter sequences. It also relieves transcriptional repression by the chromatin Alba. In addition, SSoSSB activates reverse gyrase activity, which involves DNA binding, DNA cleavage, strand passage and ligation. SSoSSB stimulates all these steps in the presence of the chromatin protein, Sul7d. SSoSSB antagonizes the inhibitory effect of Sul7d on reverse gyrase supercoiling activity. It also physically and functionally interacts with Mini-chromosome Maintenance (MCM), stimulating the DNA helicase activity of MCM.


:

Pssm-ID: 239937 [Multi-domain]  Cd Length: 82  Bit Score: 82.29  E-value: 1.64e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  43 NLIFIVLETGRV-TKTKDGHE--VRTCKVADKTGSINISVWDD-VGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQ 118
Cdd:cd04491     1 SVEGKVLSISEPrEFTRDGSEgkVQSGLVGDETGTIRFTLWDEkAADDLEPGDVVRIENAYVREFNGRLELSVGKNSEIE 80


                  ..
gi 2217291011 119 KI 120
Cdd:cd04491    81 KL 82
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
131-178 3.34e-03

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14971:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 614  Bit Score: 38.22  E-value: 3.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2217291011 131 PNFSEPNPEYSTQQAPNKAVQNDSNPSASQPTTGPSAASPASENQNGN 178
Cdd:PRK14971  381 PVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVS 428
 
Name Accession Description Interval E-value
SoSSB_OBF cd04491
SoSSB_OBF: A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus ...
 43-120 1.64e-20

SoSSB_OBF: A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In vitro, SSoSSB can substitute for the basal transcription factor TBP, stimulating transcription from promoters under conditions in which TBP is limiting, and supporting transcription when TBP is absent. SSoSSB selectively melts the duplex DNA of promoter sequences. It also relieves transcriptional repression by the chromatin Alba. In addition, SSoSSB activates reverse gyrase activity, which involves DNA binding, DNA cleavage, strand passage and ligation. SSoSSB stimulates all these steps in the presence of the chromatin protein, Sul7d. SSoSSB antagonizes the inhibitory effect of Sul7d on reverse gyrase supercoiling activity. It also physically and functionally interacts with Mini-chromosome Maintenance (MCM), stimulating the DNA helicase activity of MCM.


Pssm-ID: 239937 [Multi-domain]  Cd Length: 82  Bit Score: 82.29  E-value: 1.64e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  43 NLIFIVLETGRV-TKTKDGHE--VRTCKVADKTGSINISVWDD-VGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQ 118
Cdd:cd04491     1 SVEGKVLSISEPrEFTRDGSEgkVQSGLVGDETGTIRFTLWDEkAADDLEPGDVVRIENAYVREFNGRLELSVGKNSEIE 80


                  ..
gi 2217291011 119 KI 120
Cdd:cd04491    81 KL 82
PRK06461 PRK06461
single-stranded DNA-binding protein; Reviewed
 26-139 1.15e-17

single-stranded DNA-binding protein; Reviewed


Pssm-ID: 180574 [Multi-domain]  Cd Length: 129  Bit Score: 76.23  E-value: 1.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  26 MTTETFVKDIKPGLKNLNLIFIVLETG--RVTKTKDG-HEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASV 102
Cdd:PRK06461    1 MEMITKIKDLKPGMERVNVTVRVLEVGepKVIQTKGGpRTISEAVVGDETGRVKLTLWGEQAGSLKEGEVVEIENAWTTL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2217291011 103 FKGCLTLYTGRGGDLQKIGEfcmvySEVP---NFSEPNPE 139
Cdd:PRK06461   81 YRGKVQLNVGKYGSISESDD-----EEVPeaeEIPEETPE 115
RFA1 COG1599
ssDNA-binding replication factor A, large subunit [Replication, recombination and repair];
32-122 2.41e-12

ssDNA-binding replication factor A, large subunit [Replication, recombination and repair];


Pssm-ID: 441207 [Multi-domain]  Cd Length: 282  Bit Score: 64.70  E-value: 2.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  32 VKDIKPGLKNLNLIFIVLETG--RVTKTKDGHE--VRTCKVADKTGSINISVWDDVGNL-IQPGDIIRLTKGYASVFKGC 106
Cdd:COG1599    24 ISDLSPGDRDVNVEGRVLEIGeeRTFDRKDGSEgrVQSGVIGDETGRIRFTLWDDKADLeLEEGDVVRIENAYVREFNGG 103

                          90
                  ....*....|....*.
gi 2217291011 107 LTLYTGRGGDLQKIGE 122
Cdd:COG1599   104 PELNLGERTTIEKLDE 119
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
131-178 3.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 38.22  E-value: 3.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2217291011 131 PNFSEPNPEYSTQQAPNKAVQNDSNPSASQPTTGPSAASPASENQNGN 178
Cdd:PRK14971  381 PVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVS 428
 
Name Accession Description Interval E-value
SoSSB_OBF cd04491
SoSSB_OBF: A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus ...
 43-120 1.64e-20

SoSSB_OBF: A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In vitro, SSoSSB can substitute for the basal transcription factor TBP, stimulating transcription from promoters under conditions in which TBP is limiting, and supporting transcription when TBP is absent. SSoSSB selectively melts the duplex DNA of promoter sequences. It also relieves transcriptional repression by the chromatin Alba. In addition, SSoSSB activates reverse gyrase activity, which involves DNA binding, DNA cleavage, strand passage and ligation. SSoSSB stimulates all these steps in the presence of the chromatin protein, Sul7d. SSoSSB antagonizes the inhibitory effect of Sul7d on reverse gyrase supercoiling activity. It also physically and functionally interacts with Mini-chromosome Maintenance (MCM), stimulating the DNA helicase activity of MCM.


Pssm-ID: 239937 [Multi-domain]  Cd Length: 82  Bit Score: 82.29  E-value: 1.64e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  43 NLIFIVLETGRV-TKTKDGHE--VRTCKVADKTGSINISVWDD-VGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQ 118
Cdd:cd04491     1 SVEGKVLSISEPrEFTRDGSEgkVQSGLVGDETGTIRFTLWDEkAADDLEPGDVVRIENAYVREFNGRLELSVGKNSEIE 80


                  ..
gi 2217291011 119 KI 120
Cdd:cd04491    81 KL 82
PRK06461 PRK06461
single-stranded DNA-binding protein; Reviewed
 26-139 1.15e-17

single-stranded DNA-binding protein; Reviewed


Pssm-ID: 180574 [Multi-domain]  Cd Length: 129  Bit Score: 76.23  E-value: 1.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  26 MTTETFVKDIKPGLKNLNLIFIVLETG--RVTKTKDG-HEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASV 102
Cdd:PRK06461    1 MEMITKIKDLKPGMERVNVTVRVLEVGepKVIQTKGGpRTISEAVVGDETGRVKLTLWGEQAGSLKEGEVVEIENAWTTL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2217291011 103 FKGCLTLYTGRGGDLQKIGEfcmvySEVP---NFSEPNPE 139
Cdd:PRK06461   81 YRGKVQLNVGKYGSISESDD-----EEVPeaeEIPEETPE 115
RFA1 COG1599
ssDNA-binding replication factor A, large subunit [Replication, recombination and repair];
32-122 2.41e-12

ssDNA-binding replication factor A, large subunit [Replication, recombination and repair];


Pssm-ID: 441207 [Multi-domain]  Cd Length: 282  Bit Score: 64.70  E-value: 2.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  32 VKDIKPGLKNLNLIFIVLETG--RVTKTKDGHE--VRTCKVADKTGSINISVWDDVGNL-IQPGDIIRLTKGYASVFKGC 106
Cdd:COG1599    24 ISDLSPGDRDVNVEGRVLEIGeeRTFDRKDGSEgrVQSGVIGDETGRIRFTLWDDKADLeLEEGDVVRIENAYVREFNGG 103

                          90
                  ....*....|....*.
gi 2217291011 107 LTLYTGRGGDLQKIGE 122
Cdd:COG1599   104 PELNLGERTTIEKLDE 119
YhaM COG3481
3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation, HD superfamily ...
 26-109 1.01e-07

3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation, HD superfamily [Translation, ribosomal structure and biogenesis]; 3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation, HD superfamily is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 442704 [Multi-domain]  Cd Length: 316  Bit Score: 51.35  E-value: 1.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  26 MTTETFVKDIKPGlKNLNLIFIVLETgRVTKTKDGHEVRTCKVADKTGSINISVWDD---VGNLIQPGDIIRLtKGYASV 102
Cdd:COG3481     1 MMKRKFIKDLKPG-EEVDGFFLIKSK-ELRTTKNGKPYLSLTLQDKTGTIEAKIWDAseeDIEEFQPGDVVKV-RGKVQE 77


                  ....*..
gi 2217291011 103 FKGCLTL 109
Cdd:COG3481    78 YQGRLQL 84
PRK14699 PRK14699
replication factor A; Provisional
 32-155 1.38e-07

replication factor A; Provisional


Pssm-ID: 173162 [Multi-domain]  Cd Length: 484  Bit Score: 51.54  E-value: 1.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  32 VKDIKPGLKNLNLIFIVLETG--RVTKTKDGH--EVRTCKVADKTGSINISVWDDVG---NLIQPGDIIRLTKGYA--SV 102
Cdd:PRK14699  169 IKDIKDGMGDLNLTGKVLEISeiRTFQRKDGTsgKVGNLLLGDETGTLRVTLWDDKTdflNQIEYGDTVELINAYAreNA 248

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2217291011 103 FKGCLTLYTGRGGDLQKigefcmvysevpnfSEPNPEYSTQQAPNKAVQNDSN 155
Cdd:PRK14699  249 FTQKVELQVGNRSIIRK--------------SEKKVEYEEEFTPIEDIKADMN 287
PRK07218 PRK07218
Single-stranded DNA binding protein;
6-99 2.27e-07

Single-stranded DNA binding protein;


Pssm-ID: 180890 [Multi-domain]  Cd Length: 423  Bit Score: 50.78  E-value: 2.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011   6 PSIEPSSSIPHPVGCRGSGSMTTETFVKDIKPGLKNLNLIFIVLETGRVTKTKDG--HEVRTCKVADKTGSINISVWDDV 83
Cdd:PRK07218   35 PIDEAKQSIRRKYGGGGSGGTPSSKDIKELSTDDKNVTVTGRVLTIGERSIRYQGddHVIYEGILADETGTISYTAWKDF 114

                          90
                  ....*....|....*.
gi 2217291011  84 GnlIQPGDIIRLTKGY 99
Cdd:PRK07218  115 G--LSPGDTVTIGNAG 128
PRK07211 PRK07211
single-stranded DNA binding protein;
32-122 4.50e-07

single-stranded DNA binding protein;


Pssm-ID: 180887 [Multi-domain]  Cd Length: 485  Bit Score: 49.76  E-value: 4.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  32 VKDIKPGLKNLNLIFIVLETG--RVTKTKDGHE--VRTCKVADKTGSINISVWDDVGNL---IQPGDIIRLTKGYASVFK 104
Cdd:PRK07211  164 VEDLSLGLSDVTLVGVVLDTDsvRTFDRDDGSEgrVSNLTVGDETGRVRVTLWDDRADLaeeLDAGESVEIVDGYVRERD 243

                          90
                  ....*....|....*...
gi 2217291011 105 GCLTLYTGRGGDLQKIGE 122
Cdd:PRK07211  244 GSLELHVGDRGAVEEVDE 261
PRK15491 PRK15491
replication factor A; Provisional
 14-122 7.92e-07

replication factor A; Provisional


Pssm-ID: 185388 [Multi-domain]  Cd Length: 374  Bit Score: 49.11  E-value: 7.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  14 IPHPVGCRGSGSMTTEtfVKDIKPGLKNLNLI---FIVLETGRVTKTkDGHE--VRTCKVADKTGSINISVWDDVGNLIQ 88
Cdd:PRK15491   44 VAHDLGVTDTGVDTTK--IADINESSSNVNFTakvVSIFEPKEFNRN-DGTTgrVGNIIVADETGSIRLTLWDDLADLIK 120

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2217291011  89 PGDI-----IRLTkGYASVFKGCLTLYTGRGGDLQKIGE 122
Cdd:PRK15491  121 TGDIevgksLNIS-GYAKEGYSGIEVNIGRYGGISESDE 158
PRK12366 PRK12366
replication factor A; Reviewed
 63-115 1.17e-06

replication factor A; Reviewed


Pssm-ID: 237078 [Multi-domain]  Cd Length: 637  Bit Score: 48.89  E-value: 1.17e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2217291011  63 VRTCKVADKTGSINISVWDDVGNL-IQPGDIIRLTKGYASVFKGCLTLYTGRGG 115
Cdd:PRK12366  436 VRNIELADGTGSIRLTLWDDDAEIeIKEGDAIKILHPYVKENGDYLDLSIGRYG 489
PRK12366 PRK12366
replication factor A; Reviewed
 32-97 5.55e-06

replication factor A; Reviewed


Pssm-ID: 237078 [Multi-domain]  Cd Length: 637  Bit Score: 46.58  E-value: 5.55e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217291011  32 VKDIKPGLKNLNLifivleTGRVT--------KTKDGHE--VRTCKVADKTGSINISVWDDVGNLIQP---GDIIRLTK 97
Cdd:PRK12366   66 ISDIEEGQINVEI------TGRIIeisniktfTRKDGSTgkLANITIADNTGTIRLTLWNDNAKLLKGlkeGDVIKIEN 138
PRK15491 PRK15491
replication factor A; Provisional
 32-100 2.77e-04

replication factor A; Provisional


Pssm-ID: 185388 [Multi-domain]  Cd Length: 374  Bit Score: 41.41  E-value: 2.77e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217291011  32 VKDIKPGLKNLNLIFIVLETG--RVTKTKDGHE--VRTCKVADKTGSINISVWDDVGNL---IQPGDIIRLTKGYA 100
Cdd:PRK15491  169 ISDIKDGDSDINIVGKVLDISdvRTFQKKDGSQgrVRNITIGDETGKIRVTLWDGKTDLadkLENGDSVEIINGYA 244
PRK07211 PRK07211
single-stranded DNA binding protein;
32-102 5.26e-04

single-stranded DNA binding protein;


Pssm-ID: 180887 [Multi-domain]  Cd Length: 485  Bit Score: 40.51  E-value: 5.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  32 VKDIKPGLKNLNLIFIVLETGRV-TKTKDGHE----VRTCKVADKTGSINISVWDD-----VGNLiQPGDIIRL----TK 97
Cdd:PRK07211   56 IADIEPGMDEVKFLAKVLSIGDLrTFERDGEDedgrVINVEVADETGSVRVAFWDEqavaaEEEL-EVGQVLRIkgrpKD 134


                  ....*
gi 2217291011  98 GYASV 102
Cdd:PRK07211  135 GYNGL 139
PRK14699 PRK14699
replication factor A; Provisional
 29-143 6.10e-04

replication factor A; Provisional


Pssm-ID: 173162 [Multi-domain]  Cd Length: 484  Bit Score: 40.37  E-value: 6.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217291011  29 ETF--VKDIKPGLKNLNLIFIVLETG--RVTKTKDGHEVRTCKV--ADKTGSINISVWDDVGNLIQPGDI---IRLTKGY 99
Cdd:PRK14699  274 EEFtpIEDIKADMNNINISGRVLDISevRTFEKKDGSPGRVGNLllGDSTGKIRLTLWDEKTNFLDEIDFdetVEVLNAY 353

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2217291011 100 A--SVFKGCLTLYTGRGGDLQKiGEFCMVYSEvpNFSE-----PNPEYSTQ 143
Cdd:PRK14699  354 SreNTFSQQVELNLGARGIIQK-SEKKVEYRE--KFTDiadiiPGESYSVQ 401
PRK12366 PRK12366
replication factor A; Reviewed
 44-101 2.59e-03

replication factor A; Reviewed


Pssm-ID: 237078 [Multi-domain]  Cd Length: 637  Bit Score: 38.49  E-value: 2.59e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217291011  44 LIFIVLETGRVTKtKDGHE--VRTCKVADKTGSINISVWDDVGNL-IQPGDIIRLtKGYAS 101
Cdd:PRK12366  192 EVTKAYPIKEFTR-KDGSEgkLKSFILKDDTGSIRVTLWNDLTDIeVNKGDIVRV-KGYVK 250
YhaM_OBF_like cd04492
YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and ...
 56-105 3.15e-03

YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is inactive in the presence of Mg2+. YhaM also has a Mn2+ dependent 3'-to-5'single-stranded DNA exonuclease activity. SaCBF is also a double-stranded DNA binding protein, binding specifically to cmp, the replication enhancer found in S. aureus plasmid pT181. Proteins in this group combine an N-terminal OB fold with a C-terminal HD domain. The HD domain is found in metal-dependent phosphohydrolases.


Pssm-ID: 239938 [Multi-domain]  Cd Length: 83  Bit Score: 35.64  E-value: 3.15e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2217291011  56 KTKDGHEVRTCKVADKTGSINISVWDDVGNL---IQPGDIIRLtKGYASVFKG 105
Cdd:cd04492    13 TAKNGKPYLALTLQDKTGEIEAKLWDASEEDeekFKPGDIVHV-KGRVEEYRG 64
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
131-178 3.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 38.22  E-value: 3.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2217291011 131 PNFSEPNPEYSTQQAPNKAVQNDSNPSASQPTTGPSAASPASENQNGN 178
Cdd:PRK14971  381 PVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVS 428
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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