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ubinuclein-1 isoform X4 [Homo sapiens]
HUN and UBN_AB domain-containing protein( domain architecture ID 10555281)
HUN and UBN_AB domain-containing protein
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||
UBN_AB | pfam14075 | Ubinuclein conserved middle domain; Ubinuclein 1 and 2 (UBN1, UBN2) are members of a histone ... |
353-525 | 2.32e-66 | ||||
Ubinuclein conserved middle domain; Ubinuclein 1 and 2 (UBN1, UBN2) are members of a histone chaperone complex involved in the formation of a certain type of facultative heterochromatin, called senescence-associated heterochromatin foci (SAHF). The domain described here is conserved in many eukaryotes such as human, rat, drosophila, and zebra-fish and has been targeted for protein structure determination by the Joint Center for Structural Genomics. : Pssm-ID: 464081 Cd Length: 212 Bit Score: 222.18 E-value: 2.32e-66
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HUN | pfam08729 | HPC2 and ubinuclein domain; HPC2 (Histone promoter control 2) is required for cell-cycle ... |
117-168 | 3.19e-23 | ||||
HPC2 and ubinuclein domain; HPC2 (Histone promoter control 2) is required for cell-cycle regulation of histone transcription. It regulates transcription of the histone genes during the S-phase of the cell cycle by repressing transcription at other cell cycle stages. HPC2 mutants display synthetic interactions with FACT complex which allows RNA Pol II to elongate through nucleosomes. Hpc2 is one of the proteins of one of the multi-subunit complexes that mediate replication- independent nucleosome assembly, along with histone chaperone proteins. the Hip4 sequence from SCH. pombe is an integral component of this complex that is required for transcriptional silencing at multiple loci. HPC2, ubinuclein/yemanuclein, and the cell cycle regulator FLJ25778 share a conserved domain that is predicted to bind histone tails. This domain is also referred to as the HRD or Hpc2-related domain. : Pssm-ID: 462581 [Multi-domain] Cd Length: 52 Bit Score: 93.49 E-value: 3.19e-23
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Name | Accession | Description | Interval | E-value | ||||
UBN_AB | pfam14075 | Ubinuclein conserved middle domain; Ubinuclein 1 and 2 (UBN1, UBN2) are members of a histone ... |
353-525 | 2.32e-66 | ||||
Ubinuclein conserved middle domain; Ubinuclein 1 and 2 (UBN1, UBN2) are members of a histone chaperone complex involved in the formation of a certain type of facultative heterochromatin, called senescence-associated heterochromatin foci (SAHF). The domain described here is conserved in many eukaryotes such as human, rat, drosophila, and zebra-fish and has been targeted for protein structure determination by the Joint Center for Structural Genomics. Pssm-ID: 464081 Cd Length: 212 Bit Score: 222.18 E-value: 2.32e-66
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HUN | pfam08729 | HPC2 and ubinuclein domain; HPC2 (Histone promoter control 2) is required for cell-cycle ... |
117-168 | 3.19e-23 | ||||
HPC2 and ubinuclein domain; HPC2 (Histone promoter control 2) is required for cell-cycle regulation of histone transcription. It regulates transcription of the histone genes during the S-phase of the cell cycle by repressing transcription at other cell cycle stages. HPC2 mutants display synthetic interactions with FACT complex which allows RNA Pol II to elongate through nucleosomes. Hpc2 is one of the proteins of one of the multi-subunit complexes that mediate replication- independent nucleosome assembly, along with histone chaperone proteins. the Hip4 sequence from SCH. pombe is an integral component of this complex that is required for transcriptional silencing at multiple loci. HPC2, ubinuclein/yemanuclein, and the cell cycle regulator FLJ25778 share a conserved domain that is predicted to bind histone tails. This domain is also referred to as the HRD or Hpc2-related domain. Pssm-ID: 462581 [Multi-domain] Cd Length: 52 Bit Score: 93.49 E-value: 3.19e-23
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Name | Accession | Description | Interval | E-value | ||||
UBN_AB | pfam14075 | Ubinuclein conserved middle domain; Ubinuclein 1 and 2 (UBN1, UBN2) are members of a histone ... |
353-525 | 2.32e-66 | ||||
Ubinuclein conserved middle domain; Ubinuclein 1 and 2 (UBN1, UBN2) are members of a histone chaperone complex involved in the formation of a certain type of facultative heterochromatin, called senescence-associated heterochromatin foci (SAHF). The domain described here is conserved in many eukaryotes such as human, rat, drosophila, and zebra-fish and has been targeted for protein structure determination by the Joint Center for Structural Genomics. Pssm-ID: 464081 Cd Length: 212 Bit Score: 222.18 E-value: 2.32e-66
|
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HUN | pfam08729 | HPC2 and ubinuclein domain; HPC2 (Histone promoter control 2) is required for cell-cycle ... |
117-168 | 3.19e-23 | ||||
HPC2 and ubinuclein domain; HPC2 (Histone promoter control 2) is required for cell-cycle regulation of histone transcription. It regulates transcription of the histone genes during the S-phase of the cell cycle by repressing transcription at other cell cycle stages. HPC2 mutants display synthetic interactions with FACT complex which allows RNA Pol II to elongate through nucleosomes. Hpc2 is one of the proteins of one of the multi-subunit complexes that mediate replication- independent nucleosome assembly, along with histone chaperone proteins. the Hip4 sequence from SCH. pombe is an integral component of this complex that is required for transcriptional silencing at multiple loci. HPC2, ubinuclein/yemanuclein, and the cell cycle regulator FLJ25778 share a conserved domain that is predicted to bind histone tails. This domain is also referred to as the HRD or Hpc2-related domain. Pssm-ID: 462581 [Multi-domain] Cd Length: 52 Bit Score: 93.49 E-value: 3.19e-23
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Blast search parameters | ||||
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