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Conserved domains on  [gi|2217307514|ref|XP_047290611|]
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bifunctional peptidase and arginyl-hydroxylase JMJD5 isoform X3 [Homo sapiens]

Protein Classification

cupin domain-containing protein( domain architecture ID 1562428)

cupin domain-containing protein, part of a functionally diverse superfamily with the active site generally located at the center of a conserved domain forming a beta-barrel fold

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cupin_8 super family cl46322
Cupin-like domain; This cupin like domain shares similarity to the JmjC domain.
 195-292 6.77e-12

Cupin-like domain; This cupin like domain shares similarity to the JmjC domain.


The actual alignment was detected with superfamily member pfam13621:

Pssm-ID: 463936  Cd Length: 251  Bit Score: 64.31  E-value: 6.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217307514 195 FREQFLVPGRPVILKGVADHWPCMQKWS----LEYIQEIAGCRTVPVEVGS-------RYTDE----EWSQTLMTVNEFI 259
Cdd:pfam13621   4 FFREYVAKNKPVVIRGAVKDWPAVQKWTdsslLDYLKDKYGDVEVTVEVTPdgradrlFYNDDftfvNPKEERMPFGEFL 83

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2217307514 260 SKYIVNEPRD---VGYLAQHQLFDQIPELKQDISIP 292
Cdd:pfam13621  84 DRLEAGEDTDtapYAYLQSDNLRSEFPELLEDNDLP 119
 
Name Accession Description Interval E-value
Cupin_8 pfam13621
Cupin-like domain; This cupin like domain shares similarity to the JmjC domain.
 195-292 6.77e-12

Cupin-like domain; This cupin like domain shares similarity to the JmjC domain.


Pssm-ID: 463936  Cd Length: 251  Bit Score: 64.31  E-value: 6.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217307514 195 FREQFLVPGRPVILKGVADHWPCMQKWS----LEYIQEIAGCRTVPVEVGS-------RYTDE----EWSQTLMTVNEFI 259
Cdd:pfam13621   4 FFREYVAKNKPVVIRGAVKDWPAVQKWTdsslLDYLKDKYGDVEVTVEVTPdgradrlFYNDDftfvNPKEERMPFGEFL 83

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2217307514 260 SKYIVNEPRD---VGYLAQHQLFDQIPELKQDISIP 292
Cdd:pfam13621  84 DRLEAGEDTDtapYAYLQSDNLRSEFPELLEDNDLP 119
 
Name Accession Description Interval E-value
Cupin_8 pfam13621
Cupin-like domain; This cupin like domain shares similarity to the JmjC domain.
 195-292 6.77e-12

Cupin-like domain; This cupin like domain shares similarity to the JmjC domain.


Pssm-ID: 463936  Cd Length: 251  Bit Score: 64.31  E-value: 6.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217307514 195 FREQFLVPGRPVILKGVADHWPCMQKWS----LEYIQEIAGCRTVPVEVGS-------RYTDE----EWSQTLMTVNEFI 259
Cdd:pfam13621   4 FFREYVAKNKPVVIRGAVKDWPAVQKWTdsslLDYLKDKYGDVEVTVEVTPdgradrlFYNDDftfvNPKEERMPFGEFL 83

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2217307514 260 SKYIVNEPRD---VGYLAQHQLFDQIPELKQDISIP 292
Cdd:pfam13621  84 DRLEAGEDTDtapYAYLQSDNLRSEFPELLEDNDLP 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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