|
Name |
Accession |
Description |
Interval |
E-value |
| DUF4482 |
pfam14818 |
Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately ... |
1266-1389 |
1.36e-52 |
|
Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with pfam11365.
Pssm-ID: 464333 [Multi-domain] Cd Length: 138 Bit Score: 181.42 E-value: 1.36e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 1266 MDLRWQIHHSEKNWNREKVELLDRLDRDRQEWERQKKEFLWRIEQLQKENSPRR------------GGSFLCDQKDGNVR 1333
Cdd:pfam14818 1 MDLRWQLQHTEKNWHREKMELLDRFDRERQEWESQKKIMQKKIEQLQREVSLRRkinmnerakvidGEKFVPDQKESSSP 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316421 1334 PFPHQGSLRMPR--PVAMWPCADADSIPFEDRPLSKLKESDRCSASENLYLDALSLDD 1389
Cdd:pfam14818 81 PFPDSGQCEFPRmnHPGSLSKSDSDEESFLDEGNQKLKEQKRCKASENLFLDALSLDN 138
|
|
| SOGA |
pfam11365 |
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ... |
501-595 |
1.67e-38 |
|
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.
Pssm-ID: 463264 [Multi-domain] Cd Length: 95 Bit Score: 139.36 E-value: 1.67e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 501 DSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANI 580
Cdd:pfam11365 1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSDSSREAELQEELKLARLQINE 80
|
90
....*....|....*
gi 2217316421 581 LGRKIVELEVENRGL 595
Cdd:pfam11365 81 LSGKVMKLQYENRVL 95
|
|
| SOGA |
pfam11365 |
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ... |
630-722 |
3.78e-38 |
|
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.
Pssm-ID: 463264 [Multi-domain] Cd Length: 95 Bit Score: 138.20 E-value: 3.78e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 630 SSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREPGWLGEGASPGA--GGGAPLQEELKSARLQISE 707
Cdd:pfam11365 1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSdsSREAELQEELKLARLQINE 80
|
90
....*....|....*
gi 2217316421 708 LSGKVLKLQHENHAL 722
Cdd:pfam11365 81 LSGKVMKLQYENRVL 95
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
12-326 |
1.15e-14 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 80.75 E-value: 1.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 12 APDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFL----KDLHARPAAPGPAVP---------SSGRAPAPAAPRSP 78
Cdd:PHA03247 2563 APDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRApvddRGDPRGPAPPSPLPPdthapdpppPSPSPAANEPDPHP 2642
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 79 NLAGKAPPSPGSLAAPGRLSR----RSGGVPGAKDKPPpgagaraaggakaALGSRRAARvAPAEPLSRAGKPPGAEPPS 154
Cdd:PHA03247 2643 PPTVPPPERPRDDPAPGRVSRprraRRLGRAAQASSPP-------------QRPRRRAAR-PTVGSLTSLADPPPPPPTP 2708
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 155 AAAKgRKAKRGSRAPP----ARTVGPPTPAARIPAVTLAVTSVAGSPARCSRiSHTDSSSDLSDCPSEPLSDEQRLLPAA 230
Cdd:PHA03247 2709 EPAP-HALVSATPLPPgpaaARQASPALPAAPAPPAVPAGPATPGGPARPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 231 SSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVS------GGFAGPGvaEDVRG 304
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPppslplGGSVAPG--GDVRR 2864
|
330 340
....*....|....*....|....
gi 2217316421 305 RSPPERPV--PGTPKEPSLGEQSR 326
Cdd:PHA03247 2865 RPPSRSPAakPAAPARPPVRRLAR 2888
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
350-656 |
1.62e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 79.72 E-value: 1.62e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSyLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAK 429
Cdd:TIGR02168 689 LEEKIAELEKALAELRKE-LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 430 DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQL 509
Cdd:TIGR02168 768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 510 QFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLptgeaggppstreAELKLRLKLVEEEANILGRKIVELE 589
Cdd:TIGR02168 848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL-------------ALLRSELEELSEELRELESKRSELR 914
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217316421 590 VENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLEsstELRRHLQFVEEEAELLRRSISEIE 656
Cdd:TIGR02168 915 RELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---EAEALENKIEDDEEEARRRLKRLE 978
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
7-316 |
1.94e-10 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 66.35 E-value: 1.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 7 PAGGGAPDAklqPPGQHHRHHHLHPVAERRRLHRAPSPA-RPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAP 85
Cdd:PHA03307 122 PPASPPPSP---APDLSEMLRPVGSPGPPPAASPPAAGAsPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTP 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 86 PSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSR-RAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKR 164
Cdd:PHA03307 199 PAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSEsSGCGWGPENECPLPRPAPITLPTRIWEASGWNGP 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 165 GSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDRE 244
Cdd:PHA03307 279 SSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPP 358
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217316421 245 PPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGP-----GVAEDVRGRSPPERPVPGTP 316
Cdd:PHA03307 359 PADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGrprpsPLDAGAASGAFYARYPLLTP 435
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
345-668 |
4.14e-10 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 63.77 E-value: 4.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 345 SENDYLKDELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETgqvdgelIRSLEQD 424
Cdd:COG4372 45 EELEQLREELEQAREELEQLEE--------ELEQARSELEQLEEELEELNEQLQAAQAELAQAQEE-------LESLQEE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 425 LKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDS-- 502
Cdd:COG4372 110 AEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEll 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 503 ADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPST---REAELKLRLKLVEEEAN 579
Cdd:COG4372 190 KEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEellEEVILKEIEELELAILV 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 580 ILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHN 659
Cdd:COG4372 270 EKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVG 349
|
....*....
gi 2217316421 660 RQLTHELSK 668
Cdd:COG4372 350 LLDNDVLEL 358
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
351-708 |
4.17e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.47 E-value: 4.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 351 KDELDELRAEMEEMrDSYLEEDVYQLQELRRELDRANKNcRILQYRLRKAEQKSL----------KVAETGQVDgELIRS 420
Cdd:TIGR02169 176 LEELEEVEENIERL-DLIIDEKRQQLERLRREREKAERY-QALLKEKREYEGYELlkekealerqKEAIERQLA-SLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 421 LEQDLKVAKDVSVRLHH---ELKTVEEK-RAKAEDENETLRQQM--IEVEISK-----QALQNELERLKESSLKRRSTRE 489
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEieqLLEELNKKiKDLGEEEQLRVKEKIgeLEAEIASlersiAEKERELEDAEERLAKLEAEID 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 490 MYKEKKTfnqddsaDLRCQLQfakEEaflmRKKMAKLGREKDELEQELQKYKSLYGDVDsplptgeaggppsTREAELKL 569
Cdd:TIGR02169 333 KLLAEIE-------ELEREIE---EE----RKRRDKLTEEYAELKEELEDLRAELEEVD-------------KEFAETRD 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 570 RLKLVEEEANILGRKIVELEVENRGLKAEMedmrgqQEREGPGRDHAPSIPtspfgDSLESSTELrrhlqfvEEEAELLR 649
Cdd:TIGR02169 386 ELKDYREKLEKLKREINELKRELDRLQEEL------QRLSEELADLNAAIA-----GIEAKINEL-------EEEKEDKA 447
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2217316421 650 RSISEIEDHNRQLTHELSKFKFEpprepgwlgegASPGAGGGAPLQEELKSARLQISEL 708
Cdd:TIGR02169 448 LEIKKQEWKLEQLAADLSKYEQE-----------LYDLKEEYDRVEKELSKLQRELAEA 495
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
10-319 |
8.87e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 64.57 E-value: 8.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 10 GGAPDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPG 89
Cdd:PHA03247 2639 DPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSA 2718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 90 SLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAAR---VAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGS 166
Cdd:PHA03247 2719 TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTagpPAPAPPAAPAAGPPRRLTRPAVASLSESRESL 2798
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 167 RAPPARTVGPPTPAARIPAVTLAVTSVAGSPArcsrishtdSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSsdREPP 246
Cdd:PHA03247 2799 PSPWDPADPPAAVLAPAAALPPAASPAGPLPP---------PTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVR--RRPP 2867
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217316421 247 RGAPTPSPAARGAPPGSPEPPALLAAPLAAGACP--GGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEP 319
Cdd:PHA03247 2868 SRSPAAKPAAPARPPVRRLARPAVSRSTESFALPpdQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
352-775 |
3.69e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 62.26 E-value: 3.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 352 DELDELRAEMEEmrdsyleedvyQLQELRRELDRANKNcRILQYRLRKAEQKSLKVAetgqvdgelIRSLEQDLKVAKDV 431
Cdd:COG1196 189 ERLEDILGELER-----------QLEPLERQAEKAERY-RELKEELKELEAELLLLK---------LRELEAELEELEAE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 432 SVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQLQF 511
Cdd:COG1196 248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 512 AKEEAFLMRKKMAKLGREKDELEQELQkykslygdvdsplptgeaggppSTREAELKLRLKLVEEEANILGRKIVELEVE 591
Cdd:COG1196 328 LEEELEELEEELEELEEELEEAEEELE----------------------EAEAELAEAEEALLEAEAELAEAEEELEELA 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 592 NRGLKAEMEDMRGQQEREGPGRDHApsiptspfgdslESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKfkf 671
Cdd:COG1196 386 EELLEALRAAAELAAQLEELEEAEE------------ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE--- 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 672 epprepgwlgegaspgaggGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRApsprdsdAESDA 751
Cdd:COG1196 451 -------------------EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA-------EADYE 504
|
410 420
....*....|....*....|....
gi 2217316421 752 GKKESDGEESRLPQPKREGPVGGE 775
Cdd:COG1196 505 GFLEGVKAALLLAGLRGLAGAVAV 528
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
39-331 |
4.82e-09 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 61.73 E-value: 4.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 39 HRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLS--RRSGGVPGAKDKPPPGAG 116
Cdd:PHA03307 77 TEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEmlRPVGSPGPPPAASPPAAG 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 117 ARAAGGAKAALGSRRAARVAP-----AEPLSRAGKPPGAEPPSAAAKGRKAKRGS----RAPPARTVGPPTPAARIPAvt 187
Cdd:PHA03307 157 ASPAAVASDAASSRQAALPLSspeetARAPSSPPAEPPPSTPPAAASPRPPRRSSpisaSASSPAPAPGRSAADDAGA-- 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 188 lAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPP 267
Cdd:PHA03307 235 -SSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPR 313
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217316421 268 ALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVPAA 331
Cdd:PHA03307 314 ASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSS 377
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
350-725 |
8.00e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 60.80 E-value: 8.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRD------SYLEEDVYQLQELRRELDRANKNCRILQYRLR--KAEQKSLKvaetGQVDGELIRSL 421
Cdd:TIGR04523 237 KQQEINEKTTEISNTQTqlnqlkDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNqlKSEISDLN----NQKEQDWNKEL 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERlKESSLKR-RSTREMYKEKKTFNQD 500
Cdd:TIGR04523 313 KSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE-KQNEIEKlKKENQSYKQEIKNLES 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 501 DSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEaggppsTREAELKLRLKLVEEEANI 580
Cdd:TIGR04523 392 QINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT------NQDSVKELIIKNLDNTRES 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 581 LGRKIVELEVENRGLKAEMEDMrgQQEREGPGRDHapSIPTSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHNR 660
Cdd:TIGR04523 466 LETQLKVLSRSINKIKQNLEQK--QKELKSKEKEL--KKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIS 541
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217316421 661 QLTHELSKFKFepprepgwlgegaspgagggaplqeELKSARL--QISELSGKVLKLQHENHALLSN 725
Cdd:TIGR04523 542 DLEDELNKDDF-------------------------ELKKENLekEIDEKNKEIEELKQTQKSLKKK 583
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
8-330 |
8.49e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 61.11 E-value: 8.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 8 AGGGAPDAKLQPPGQHHRHHHLHPVAERRRlHRAPSPARPflkdlharPAAPGPAVPSSGRapapaaprspnlAGKAPPS 87
Cdd:PHA03247 2728 ARQASPALPAAPAPPAVPAGPATPGGPARP-ARPPTTAGP--------PAPAPPAAPAAGP------------PRRLTRP 2786
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 88 PGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPP--SAAAKGRKAKRG 165
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggSVAPGGDVRRRP 2866
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 166 -SRAPPARTVGPPTPAAR---IPAVTLAVTSVAGSPARCSRISHTDSssdlsdcPSEPLSDEQRLLPAASSDAEsgtgss 241
Cdd:PHA03247 2867 pSRSPAAKPAAPARPPVRrlaRPAVSRSTESFALPPDQPERPPQPQA-------PPPPQPQPQPPPPPQPQPPP------ 2933
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 242 drePPRGAPTPSPAARGAPPGSPEppallaaplAAGACPGGRSipsgvsgGFAGPGVAEDVRGRSPPERPVPGTPKEPSL 321
Cdd:PHA03247 2934 ---PPPPRPQPPLAPTTDPAGAGE---------PSGAVPQPWL-------GALVPGRVAVPRFRVPQPAPSREAPASSTP 2994
|
....*....
gi 2217316421 322 GEQSRLVPA 330
Cdd:PHA03247 2995 PLTGHSLSR 3003
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
350-542 |
1.22e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 60.12 E-value: 1.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDsyleedvyqlqELRRELDRANKNCRILQYRLRKAEqKSLKVAETG------QVD--GELIRSL 421
Cdd:pfam05483 546 LRDELESVREEFIQKGD-----------EVKCKLDKSEENARSIEYEVLKKE-KQMKILENKcnnlkkQIEnkNKNIEEL 613
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQ---QMI-----EVEISKQALQNELERLKESSLKRRSTREMYKE 493
Cdd:pfam05483 614 HQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQkfeEIIdnyqkEIEDKKISEEKLLEEVEKAKAIADEAVKLQKE 693
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2217316421 494 kktfnqddsADLRCQLQFAkEEAFLMRKKMAKLGREKDELEQELQKYKS 542
Cdd:pfam05483 694 ---------IDKRCQHKIA-EMVALMEKHKHQYDKIIEERDSELGLYKN 732
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
370-672 |
2.94e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.30 E-value: 2.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 370 EEDVYQLQELRRELDRANKNCRI-----LQYRLRKAEQKSLKVAETGQVDGELIRSLEQdLKVAKDVSVRLHHELktvEE 444
Cdd:TIGR02168 185 RENLDRLEDILNELERQLKSLERqaekaERYKELKAELRELELALLVLRLEELREELEE-LQEELKEAEEELEEL---TA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 445 KRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRRstREMYKEKKTFNQDDSADLRCQLQFAKEEAFLMRKK 522
Cdd:TIGR02168 261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANeiSRLEQQ--KQILRERLANLERQLEELEAQLEELESKLDELAEE 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 523 MAKLGREKDELEQELQkykslygDVDSPLPTGEAggppstREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDM 602
Cdd:TIGR02168 339 LAELEEKLEELKEELE-------SLEAELEELEA------ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL 405
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316421 603 RGQQER--------EGPGRDHAPSIPTSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFE 672
Cdd:TIGR02168 406 EARLERledrrerlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
350-670 |
3.38e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.92 E-value: 3.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDRANKNCRILQYRLR---------KAEQKSL--KVAETGQVDG--- 415
Cdd:PRK03918 219 LREELEKLEKEVKE-----LEELKEEIEELEKELESLEGSKRKLEEKIReleerieelKKEIEELeeKVKELKELKEkae 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 416 ---ELIRSLEQDLKVAKDVSVRL---HHELKTVEEKRAKAEDENETLRqqmiEVEISKQALQNELERLKESSLK----RR 485
Cdd:PRK03918 294 eyiKLSEFYEEYLDELREIEKRLsrlEEEINGIEERIKELEEKEERLE----ELKKKLKELEKRLEELEERHELyeeaKA 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 486 STREMYKEKKTFNQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREA 565
Cdd:PRK03918 370 KKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEH 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 566 ELKLRLKLVEEEANILGRKIvELEVENRGLKAEMEDMRGQQEREgpgRDHAPSIPTSPFGDSLESSTEL--RRHLQFVEE 643
Cdd:PRK03918 450 RKELLEEYTAELKRIEKELK-EIEEKERKLRKELRELEKVLKKE---SELIKLKELAEQLKELEEKLKKynLEELEKKAE 525
|
330 340
....*....|....*....|....*..
gi 2217316421 644 EAELLRRSISEIEDHNRQLTHELSKFK 670
Cdd:PRK03918 526 EYEKLKEKLIKLKGEIKSLKKELEKLE 552
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
443-769 |
3.60e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.93 E-value: 3.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 443 EEKRAKAEDENETLRQQMIEVEISKQALQNELERLKesslKRRSTREMYKEKKTFNQDDSADLRC-QLQFAKEEAFLMRK 521
Cdd:TIGR02169 169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLR----REREKAERYQALLKEKREYEGYELLkEKEALERQKEAIER 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 522 KMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANI----------------LGRKI 585
Cdd:TIGR02169 245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIaslersiaekereledAEERL 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 586 VELEVENRGLKAEMEDMRGQQEREGPGRDHApsipTSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHE 665
Cdd:TIGR02169 325 AKLEAEIDKLLAEIEELEREIEEERKRRDKL----TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 666 LSKFKFEPPRepgwLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQRcdLAAHLGlrapsprDS 745
Cdd:TIGR02169 401 INELKRELDR----LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ--LAADLS-------KY 467
|
330 340
....*....|....*....|....
gi 2217316421 746 DAESDAGKKESDGEESRLPQPKRE 769
Cdd:TIGR02169 468 EQELYDLKEEYDRVEKELSKLQRE 491
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
85-331 |
5.34e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.41 E-value: 5.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 85 PPSPGSLAAPGRLSRRSggVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPlsrAGKPPGAEPPSAAAKGRKAKR 164
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRS--VPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDD---RGDPRGPAPPSPLPPDTHAPD 2625
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 165 ---GSRAPPARTVGPPTPAARIPAvtlAVTSVAGSPARCSRISHTDSSSDlsdcPSEPLSDEQRLLPAASSDAESGTGSS 241
Cdd:PHA03247 2626 pppPSPSPAANEPDPHPPPTVPPP---ERPRDDPAPGRVSRPRRARRLGR----AAQASSPPQRPRRRAARPTVGSLTSL 2698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 242 DREPPRGaPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSL 321
Cdd:PHA03247 2699 ADPPPPP-PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA 2777
|
250
....*....|
gi 2217316421 322 GEQSRLVPAA 331
Cdd:PHA03247 2778 GPPRRLTRPA 2787
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
350-609 |
6.17e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.02 E-value: 6.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSyLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETgqvdgelIRSLEQDLKVAK 429
Cdd:COG1196 265 LEAELEELRLELEELELE-LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE-------LAELEEELEELE 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 430 DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQL 509
Cdd:COG1196 337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 510 QFAKEEAFLMRKKMAKLGREKDELEQELQkykslygdvdsplptgeaggppstreaELKLRLKLVEEEANILGRKIVELE 589
Cdd:COG1196 417 ERLEEELEELEEALAELEEEEEEEEEALE---------------------------EAAEEEAELEEEEEALLELLAELL 469
|
250 260
....*....|....*....|
gi 2217316421 590 VENRGLKAEMEDMRGQQERE 609
Cdd:COG1196 470 EEAALLEAALAELLEELAEA 489
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
7-264 |
7.79e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 57.55 E-value: 7.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 7 PAGGGAPDAKLQPP---GQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGK 83
Cdd:PRK07003 362 VTGGGAPGGGVPARvagAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDD 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 84 APPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAK 163
Cdd:PRK07003 442 AADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDA 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 164 RGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCS--RIShtdsssdlsdcpseplSDEQRLLPAASSDAESGTGSS 241
Cdd:PRK07003 522 PAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAgmRVS----------------SDRGARAAAAAKPAAAPAAAP 585
|
250 260
....*....|....*....|....
gi 2217316421 242 DREPPRGA-PTPSPAARGAPPGSP 264
Cdd:PRK07003 586 KPAAPRVAvQVPTPRARAATGDAP 609
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
345-661 |
8.65e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.77 E-value: 8.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 345 SENDYLKDELDELRAEMEEMRDSyLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKV-AETGQVDGElIRSLEQ 423
Cdd:TIGR02169 695 SELRRIENRLDELSQELSDASRK-IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVkSELKELEAR-IEELEE 772
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 424 DLKVAK----DVSVRL-HHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFN 498
Cdd:TIGR02169 773 DLHKLEealnDLEARLsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSI 852
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 499 QDDSADLRCQL-----QFAKEEAFL--MRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEaggppsTREAELKLRL 571
Cdd:TIGR02169 853 EKEIENLNGKKeeleeELEELEAALrdLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR------KRLSELKAKL 926
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 572 KLVEEEANILGRKIVELEVEN------RGLKAEMEDMRGQQEREGPGRDHAPsiptSPFGDSLESSTELRRHLQFVEEEA 645
Cdd:TIGR02169 927 EALEEELSEIEDPKGEDEEIPeeelslEDVQAELQRVEEEIRALEPVNMLAI----QEYEEVLKRLDELKEKRAKLEEER 1002
|
330
....*....|....*.
gi 2217316421 646 ELLRRSISEIEDHNRQ 661
Cdd:TIGR02169 1003 KAILERIEEYEKKKRE 1018
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
133-383 |
1.48e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 56.92 E-value: 1.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 133 ARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSR-APPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSD 211
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAApAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 212 LSDCPSEPLSdeqrllPAASSDAESGTGSSDRePPRGAPTPSPAARGAPPGSPEPPallaaplaagacPGGRSIPSGVSG 291
Cdd:PRK07764 666 GDGWPAKAGG------AAPAAPPPAPAPAAPA-APAGAAPAQPAPAPAATPPAGQA------------DDPAAQPPQAAQ 726
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 292 GFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVPAAEEEELLREMEELRSEndylkdELDELRAEMEEMRDSYLEE 371
Cdd:PRK07764 727 GASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE------EEEMAEDDAPSMDDEDRRD 800
|
250
....*....|...
gi 2217316421 372 -DVYQLQELRREL 383
Cdd:PRK07764 801 aEEVAMELLEEEL 813
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
81-331 |
1.63e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 56.78 E-value: 1.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 81 AGKAPPS-PGSLAAPGrlsRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKG 159
Cdd:PRK07003 369 GGGVPARvAGAVPAPG---ARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADG 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 160 RKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARcsrishtdsssdlSDCPSEPLSdeqrllPAASSDAESGTG 239
Cdd:PRK07003 446 DAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAP-------------PDAAFEPAP------RAAAPSAATPAA 506
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 240 SSDREPPRGAPTPSPAARGAPPgSPEPPALLAAPLAAGACPGGRSIP---------------SGVSGGFAGPGVAEDVRG 304
Cdd:PRK07003 507 VPDARAPAAASREDAPAAAAPP-APEARPPTPAAAAPAARAGGAAAAldvlrnagmrvssdrGARAAAAAKPAAAPAAAP 585
|
250 260 270
....*....|....*....|....*....|
gi 2217316421 305 RSPPER---PVPgTPKEPSLGEQSRLVPAA 331
Cdd:PRK07003 586 KPAAPRvavQVP-TPRARAATGDAPPNGAA 614
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
350-662 |
2.06e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 56.31 E-value: 2.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYLE--------EDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETgqvdGELIRSL 421
Cdd:COG4717 93 LQEELEELEEELEELEAELEElreeleklEKLLQLLPLYQELEALEAELAELPERLEELEERLEELREL----EEELEEL 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 422 EQDLKVAK--------DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKE 493
Cdd:COG4717 169 EAELAELQeeleelleQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEA 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 494 K---------------------KTFNQDDSADLRCQLQFAkeEAFLMRKKMAKLGREKDEL----------EQELQKYKS 542
Cdd:COG4717 249 RlllliaaallallglggsllsLILTIAGVLFLVLGLLAL--LFLLLAREKASLGKEAEELqalpaleeleEEELEELLA 326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 543 LYGdVDSPLPTGEAGGPPST-----------REAELKLRLKLVEEEANILG-----------RKIVELEVENRGLKAEME 600
Cdd:COG4717 327 ALG-LPPDLSPEELLELLDRieelqellreaEELEEELQLEELEQEIAALLaeagvedeeelRAALEQAEEYQELKEELE 405
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217316421 601 DMRGQQEREGPGRDHAPSIPTspfGDSLES-STELRRHLQFVEEEAELLRRSISEIEDHNRQL 662
Cdd:COG4717 406 ELEEQLEELLGELEELLEALD---EEELEEeLEELEEELEELEEELEELREELAELEAELEQL 465
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
39-317 |
3.00e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 55.95 E-value: 3.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 39 HRAPSPARPFLKDLHARPAA--PGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAP---GRLSRRSGGVPGAKDKP-P 112
Cdd:PHA03307 118 PPTPPPASPPPSPAPDLSEMlrPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPlssPEETARAPSSPPAEPPPsT 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 113 PGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSRA-----PPARTVGPPTPAARIPAVT 187
Cdd:PHA03307 198 PPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENecplpRPAPITLPTRIWEASGWNG 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 188 LAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARG--------- 258
Cdd:PHA03307 278 PSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSrspspsrpp 357
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316421 259 --APPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPK 317
Cdd:PHA03307 358 ppADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLD 418
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
60-265 |
5.07e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 54.99 E-value: 5.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 60 GPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAE 139
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGW 669
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 140 PLSRAGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARipavtlAVTSVAGSPARCSRISHTDSSSDLSDCPSEP 219
Cdd:PRK07764 670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAG------QADDPAAQPPQAAQGASAPSPAADDPVPLPP 743
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2217316421 220 LSDEQRLLPAASSDAESGTGSSDREPPrgAPTPSPAARGAPPGSPE 265
Cdd:PRK07764 744 EPDDPPDPAGAPAQPPPPPAPAPAAAP--AAAPPPSPPSEEEEMAE 787
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
362-670 |
8.60e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 54.30 E-value: 8.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 362 EEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVD--GELIRSLEQDLKVakdvsvrlhHEL 439
Cdd:PRK03918 447 EEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKelAEQLKELEEKLKK---------YNL 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 440 KTVEEKrakaEDENETLRQQMIEVEISKQALQNELERLKEssLKRRStREMYKEKKTfnqddsadlrcqlqfAKEEAFLM 519
Cdd:PRK03918 518 EELEKK----AEEYEKLKEKLIKLKGEIKSLKKELEKLEE--LKKKL-AELEKKLDE---------------LEEELAEL 575
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 520 RKKMAKLGREK-DELEQELQKYKSLYGDVDsplptgEAGGPPSTREAELKlRLKLVEEEANILGRKIVELEVENRGLKAE 598
Cdd:PRK03918 576 LKELEELGFESvEELEERLKELEPFYNEYL------ELKDAEKELEREEK-ELKKLEEELDKAFEELAETEKRLEELRKE 648
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217316421 599 MEDMR---GQQEREGPGRDHapsiptspfgdslessTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFK 670
Cdd:PRK03918 649 LEELEkkySEEEYEELREEY----------------LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
350-614 |
1.01e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.29 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRD--SYLEEdvyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKV 427
Cdd:TIGR02168 279 LEEEIEELQKELYALANeiSRLEQ---QKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 428 AKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRRSTRemykekktfNQDDSADL 505
Cdd:TIGR02168 356 LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEArlERLEDRRER---------LQQEIEEL 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 506 RCQLQfakeeaflmRKKMAKLGREKDELEQELQKYKslygdvdsplptgeaggppsTREAELKLRLKLVEEEANILGRKI 585
Cdd:TIGR02168 427 LKKLE---------EAELKELQAELEELEEELEELQ--------------------EELERLEEALEELREELEEAEQAL 477
|
250 260 270
....*....|....*....|....*....|
gi 2217316421 586 VELEVENRGLKAEMEDMRGQQER-EGPGRD 614
Cdd:TIGR02168 478 DAAERELAQLQARLDSLERLQENlEGFSEG 507
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
6-264 |
1.07e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 53.73 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 6 GPAGGGAPDAklqppgqhhrHHHLHPVAERRRLHRAPSPARPflkdlharPAAPGPAVPSSGRAPAPAAPRSPNLAGKAP 85
Cdd:PRK12323 366 GQSGGGAGPA----------TAAAAPVAQPAPAAAAPAAAAP--------APAAPPAAPAAAPAAAAAARAVAAAPARRS 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 86 PSPGSLAAP-GRLSRRSGGVPGAKDKPPPGAgaraaggakaalgsrrAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKR 164
Cdd:PRK12323 428 PAPEALAAArQASARGPGGAPAPAPAPAAAP----------------AAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 165 GSRAPPARTVGPPTPAARIPAvtlavtsvagsparcsrishtDSSSDLSDCPSEPLSDEqrllpaaSSDAESGTGSSDRE 244
Cdd:PRK12323 492 ADDDPPPWEELPPEFASPAPA---------------------QPDAAPAGWVAESIPDP-------ATADPDDAFETLAP 543
|
250 260
....*....|....*....|
gi 2217316421 245 PPRGAPTPSPAARGAPPGSP 264
Cdd:PRK12323 544 APAAAPAPRAAAATEPVVAP 563
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
352-542 |
1.32e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 352 DELDELRAEMEEMRDSY--LEedvyQLQELRRELDRANKNCRILQYRLRKAEqkslkvAETGQVDGELIRSLEQDLKVAK 429
Cdd:COG4913 235 DDLERAHEALEDAREQIelLE----PIRELAERYAAARERLAELEYLRAALR------LWFAQRRLELLEAELEELRAEL 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 430 DvsvRLHHELKTVEEKRAKAEDENETLRQQMIEVE-ISKQALQNELERLKESSLKRRSTREMYKE------------KKT 496
Cdd:COG4913 305 A---RLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEAllaalglplpasAEE 381
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2217316421 497 FN------QDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKS 542
Cdd:COG4913 382 FAalraeaAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
353-542 |
1.36e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.91 E-value: 1.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 353 ELDELRAEMEEMRDsylEEDVYQ--LQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQ-------VDGELIRSLEQ 423
Cdd:TIGR02168 268 KLEELRLEVSELEE---EIEELQkeLYALANEISRLEQQKQILRERLANLERQLEELEAQLEeleskldELAEELAELEE 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 424 DLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEV-----EISKQALQN---------ELERLKESSLKRRSTRE 489
Cdd:TIGR02168 345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLrskvaQLELQIASLnneierleaRLERLEDRRERLQQEIE 424
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316421 490 MYKEKKTFN-----QDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKS 542
Cdd:TIGR02168 425 ELLKKLEEAelkelQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
346-484 |
1.51e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 1.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 346 ENDYLKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDL 425
Cdd:TIGR02169 351 RRDKLTEEYAELKEELEDLRAELEEVDK-EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI 429
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316421 426 KVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKR 484
Cdd:TIGR02169 430 AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKelSKLQR 490
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
358-662 |
2.41e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.22 E-value: 2.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 358 RAEMEEMRDSYLEEDVYQLQELRREldranKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHH 437
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKA-----EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 438 ELKTVEEKRAKAEdenETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQLqfAKEEAF 517
Cdd:PTZ00121 1666 EAKKAEEDKKKAE---EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEE--AKKEAE 1740
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 518 LMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIVELEVENRG--- 594
Cdd:PTZ00121 1741 EDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGnlv 1820
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217316421 595 --LKAEMEDMRGQQ--EREGPGRDHAPSIPTSPFGDSLESSTELRRHLQFvEEEAELLRRSISEIE--DHNRQL 662
Cdd:PTZ00121 1821 inDSKEMEDSAIKEvaDSKNMQLEEADAFEKHKFNKNNENGEDGNKEADF-NKEKDLKEDDEEEIEeaDEIEKI 1893
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
54-313 |
2.51e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 52.93 E-value: 2.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 54 ARPAAPGPAVPSS-----GRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKD-------KPPPGAGARAAG 121
Cdd:PRK07003 361 AVTGGGAPGGGVParvagAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATraeappaAPAPPATADRGD 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 122 GAKAALGSRRAARVAPAEPLSRAGkPPGAEPPSAAAKgrKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCS 201
Cdd:PRK07003 441 DAADGDAPVPAKANARASADSRCD-ERDAQPPADSGS--ASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 202 RishtdssSDLSDCPSEPLSDEQRLLPAASSDAESGTG---------------SSDREPPRGAPTPSPAARGAPPGSPEP 266
Cdd:PRK07003 518 R-------EDAPAAAAPPAPEARPPTPAAAAPAARAGGaaaaldvlrnagmrvSSDRGARAAAAAKPAAAPAAAPKPAAP 590
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2217316421 267 PALLAAPLaagacPGGRSIPSGVSGGFAGPGV-AEDVRGRSPPERPVP 313
Cdd:PRK07003 591 RVAVQVPT-----PRARAATGDAPPNGAARAEqAAESRGAPPPWEDIP 633
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
354-559 |
3.09e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.61 E-value: 3.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 354 LDELRAEMEEmrdsyLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGElIRSLEQDLKVAKDVSV 433
Cdd:COG4913 612 LAALEAELAE-----LEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAERE-IAELEAELERLDASSD 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 434 rlhhELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQLQFAK 513
Cdd:COG4913 686 ----DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD 761
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2217316421 514 EEAFLMRKKM--------AKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGP 559
Cdd:COG4913 762 AVERELRENLeeridalrARLNRAEEELERAMRAFNREWPAETADLDADLESLP 815
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
350-608 |
3.53e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 52.05 E-value: 3.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRdsyleedvYQLQELRRELDRANKNCRILQYRLRKAEQkslkvaetgqvdgeLIRSLEQDlkvak 429
Cdd:pfam05557 109 LKNELSELRRQIQRAE--------LELQSTNSELEELQERLDLLKAKASEAEQ--------------LRQNLEKQ----- 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 430 dvsvrlHHELKTVEEKRAKAEDENETLRQQMIEVEISKQAL------QNELERLKESSLKRRSTRE---MYKEKKtfnqd 500
Cdd:pfam05557 162 ------QSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELaripelEKELERLREHNKHLNENIEnklLLKEEV----- 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 501 dsADLRCQLQfaKEEAflMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPP----STREAELKLRLKLVEE 576
Cdd:pfam05557 231 --EDLKRKLE--REEK--YREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRieqlQQREIVLKEENSSLTS 304
|
250 260 270
....*....|....*....|....*....|..
gi 2217316421 577 EANILGRKIVELEVENRGLKAEMEDMRGQQER 608
Cdd:pfam05557 305 SARQLEKARRELEQELAQYLKKIEDLNKKLKR 336
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
350-485 |
3.95e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.22 E-value: 3.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKncrilqyRLRKAEQKSLKVAetgqvdgELIRSLEQDLKVAK 429
Cdd:COG4913 314 LEARLDALREELDELEAQIRGNGGDRLEQLEREIERLER-------ELEERERRRARLE-------ALLAALGLPLPASA 379
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316421 430 DVSVRLHHELKtveEKRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRR 485
Cdd:COG4913 380 EEFAALRAEAA---ALLEALEEELEALEEALAEAEAALRDLRRELRELEAeiASLERR 434
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
350-589 |
4.37e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.86 E-value: 4.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEmeemrdsyLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAK 429
Cdd:COG1196 321 LEEELAELEEE--------LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 430 DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKtfnqddsADLRCQL 509
Cdd:COG1196 393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE-------EALLELL 465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 510 QFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDvdsplptgEAGGPPSTREAELKLRLKLVEEEANILGRKIVELE 589
Cdd:COG1196 466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD--------YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
350-831 |
1.07e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 50.71 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSyLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAK 429
Cdd:COG1196 314 LEERLEELEEELAELEEE-LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 430 DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQL 509
Cdd:COG1196 393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 510 QFAKEEAflmRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIVELE 589
Cdd:COG1196 473 ALLEAAL---AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 590 VENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLESSTELRRHLQFVEEEAELLRRSisEIEDHNRQLTHELSKF 669
Cdd:COG1196 550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA--DARYYVLGDTLLGRTL 627
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 670 KFEPPREPGWLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRAPSPRDSDAES 749
Cdd:COG1196 628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 750 DAGKKESDGEESRLPQPKREGPVGGESDSEEMFEktsgfgsgkpSEASEPCPTELLKAREDSEYLVTLKHEAQRLERTVE 829
Cdd:COG1196 708 ELAEAEEERLEEELEEEALEEQLEAEREELLEEL----------LEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
|
..
gi 2217316421 830 RL 831
Cdd:COG1196 778 AL 779
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
351-609 |
1.41e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 351 KDELDELRAEMEEMRDSylEEDVYQLQELRRELDRANKNCRILQY--RLRKAEQK----SLKVAETGQVDGELIRSLE-- 422
Cdd:PTZ00121 1469 AKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADEAKKAAEAKKKadEAKKAEEAkkadEAKKAEEAKKADEAKKAEEkk 1546
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 423 --QDLKVAKDVsvRLHHELKTVEEKRAKAEDENETLR--------------QQMIEVEISKQALQNELERLKESSLKRRS 486
Cdd:PTZ00121 1547 kaDELKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRkaeeakkaeearieEVMKLYEEEKKMKAEEAKKAEEAKIKAEE 1624
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 487 TREMYKEKKTFNQ---DDSADLRCQLQFAKEEaflmRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAggppSTR 563
Cdd:PTZ00121 1625 LKKAEEEKKKVEQlkkKEAEEKKKAEELKKAE----EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEA----LKK 1696
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2217316421 564 EAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERE 609
Cdd:PTZ00121 1697 EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
338-668 |
2.56e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.58 E-value: 2.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 338 REMEELRSENDYLKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRankncRILQYRLRKAEQKSLKVAETGQVDG-E 416
Cdd:pfam02463 177 KLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-----YLLYLDYLKLNEERIDLLQELLRDEqE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 417 LIRSLEQDLKVAKDVSVRLHHEL-------KTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTRE 489
Cdd:pfam02463 252 EIESSKQEIEKEEEKLAQVLKENkeeekekKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 490 MYKEKKtfnqddsadlrcqLQFAKEEAFLMRKKmAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKL 569
Cdd:pfam02463 332 KEKEEI-------------EELEKELKELEIKR-EAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 570 RLKLVEEeaNILGRKIVELEVENRGLKAEMEDMRGQQEREGpgrdhapsiptsPFGDSLESSTELRRHLQFVEEEAELLR 649
Cdd:pfam02463 398 ELKSEEE--KEAQLLLELARQLEDLLKEEKKEELEILEEEE------------ESIELKQGKLTEEKEELEKQELKLLKD 463
|
330
....*....|....*....
gi 2217316421 650 RSISEIEDHNRQLTHELSK 668
Cdd:pfam02463 464 ELELKKSEDLLKETQLVKL 482
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
346-535 |
2.60e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.35 E-value: 2.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 346 ENDYLKDELDELRAE--MEEMRDSYLEEDVYQLQELRRELDRANKN--CRILQYRLRKAEQKSLKVAETgQVDGELIRSL 421
Cdd:pfam17380 390 KNERVRQELEAARKVkiLEEERQRKIQQQKVEMEQIRAEQEEARQRevRRLEEERAREMERVRLEEQER-QQQVERLRQQ 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 422 EQDLKVAKDVSVRLHHELKTVEEKRAKA-EDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQ- 499
Cdd:pfam17380 469 EEERKRKKLELEKEKRDRKRAEEQRRKIlEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEm 548
|
170 180 190
....*....|....*....|....*....|....*.
gi 2217316421 500 DDSADLRCQLQFAKEEaflmRKKMAKLGREKDELEQ 535
Cdd:pfam17380 549 EERRRIQEQMRKATEE----RSRLEAMEREREMMRQ 580
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
41-297 |
3.12e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.40 E-value: 3.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 41 APSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPgsLAAPGRLSRRSGGVPGAKDKPPPGAGARAA 120
Cdd:PHA03307 48 AELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTL--APASPAREGSPTPPGPSSPDPPPPTPPPAS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 121 GGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAV-TSVAGSPAR 199
Cdd:PHA03307 126 PPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPsTPPAAASPR 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 200 CSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPA--------ARGAPPGSPEPPALLA 271
Cdd:PHA03307 206 PPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPApitlptriWEASGWNGPSSRPGPA 285
|
250 260
....*....|....*....|....*.
gi 2217316421 272 APLAAGACPGGRSIPSGVSGGFAGPG 297
Cdd:PHA03307 286 SSSSSPRERSPSPSPSSPGSGPAPSS 311
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
6-264 |
3.76e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 3.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 6 GPAGGGAPDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGP----AVPSSGRAPAPAAPRSPNLA 81
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPpptsAQPTAPPPPPGPPPPSLPLG 2853
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 82 GKAPP------------SPGSLAAPGR----------LSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAE 139
Cdd:PHA03247 2854 GSVAPggdvrrrppsrsPAAKPAAPARppvrrlarpaVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 140 PLSRAGKPPGAEPPSAAAKGRKAKR-----------GSRAPPARTVGPPTPAARIPAVTlaVTSVAGSPArcSRISHTDS 208
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGEPSGAvpqpwlgalvpGRVAVPRFRVPQPAPSREAPASS--TPPLTGHSL--SRVSSWAS 3009
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 209 SSDLS-DCPSEPLSDEQRLLPAASSDAESGTGSSDREPPR---GAPTPSPAARGAPPGSP 264
Cdd:PHA03247 3010 SLALHeETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERsdlEALDPLPPEPHDPFAHE 3069
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
352-591 |
4.16e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 4.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 352 DELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETgqvdgelIRSLEQDLKVAKDv 431
Cdd:COG4942 20 DAAAEAEAELEQLQQ--------EIAELEKELAALKKEEKALLKQLAALERRIAALARR-------IRALEQELAALEA- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 432 svrlhhELKTVEEKRAKAEDENETLRQQMIEV--EISKQALQNELERL--KESSLKRRSTREMYKEKKTFNQDDSADLRC 507
Cdd:COG4942 84 ------ELAELEKEIAELRAELEAQKEELAELlrALYRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 508 QLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAggppstREAELKLRLKLVEEEANILGRKIVE 587
Cdd:COG4942 158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIAR 231
|
....
gi 2217316421 588 LEVE 591
Cdd:COG4942 232 LEAE 235
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
375-539 |
5.24e-05 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 48.21 E-value: 5.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 375 QLQELRRELDRANKNcriLQYRLRKAEQKSLKVAETGQVD----GELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAE 450
Cdd:pfam07111 482 ELEQLREERNRLDAE---LQLSAHLIQQEVGRAREQGEAErqqlSEVAQQLEQELQRAQESLASVGQQLEVARQGQQEST 558
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 451 DENETLRQQMI-EVEISKQALQN---ELE-RLKE--SSLKRR---STREMYK---------EKKTFNQDDSADL-RCQLQ 510
Cdd:pfam07111 559 EEAASLRQELTqQQEIYGQALQEkvaEVEtRLREqlSDTKRRlneARREQAKavvslrqiqHRATQEKERNQELrRLQDE 638
|
170 180
....*....|....*....|....*....
gi 2217316421 511 FAKEEAFLMRKKMAKLGREKDELEQELQK 539
Cdd:pfam07111 639 ARKEEGQRLARRVQELERDKNLMLATLQQ 667
|
|
| Tropomyosin |
pfam00261 |
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ... |
350-551 |
5.33e-05 |
|
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.
Pssm-ID: 459736 [Multi-domain] Cd Length: 235 Bit Score: 46.95 E-value: 5.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYLEEDVY-------------QLQELRRELDRANKNCRILQYRLRKAEQKS------LKVAE- 409
Cdd:pfam00261 6 IKEELDEAEERLKEAMKKLEEAEKRaekaeaevaalnrRIQLLEEELERTEERLAEALEKLEEAEKAAdesergRKVLEn 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 410 TGQVDGELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTRE 489
Cdd:pfam00261 86 RALKDEEKMEILEAQLKEAKEIAEEADRKYEEVARKLVVVEGDLERAEERAELAESKIVELEEELKVVGNNLKSLEASEE 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217316421 490 MYKEKKTFNQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPL 551
Cdd:pfam00261 166 KASEREDKYEEQIRFLTEKLKEAETRAEFAERSVQKLEKEVDRLEDELEAEKEKYKAISEEL 227
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
346-895 |
5.35e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.50 E-value: 5.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 346 ENDYLKDE----LDELRAEMEEMRD-SYLEEDVYQLQELRRelDRANKNCRILQYRLRKAEQKSLKVAE---TGQVDgEL 417
Cdd:TIGR00606 502 EVKSLQNEkadlDRKLRKLDQEMEQlNHHTTTRTQMEMLTK--DKMDKDEQIRKIKSRHSDELTSLLGYfpnKKQLE-DW 578
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 418 IRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVE------ISKQALQNELERLKESSLKRRSTREM- 490
Cdd:TIGR00606 579 LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEdklfdvCGSQDEESDLERLKEEIEKSSKQRAMl 658
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 491 ----------------------------YKEKKTFNQDdSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKS 542
Cdd:TIGR00606 659 agatavysqfitqltdenqsccpvcqrvFQTEAELQEF-ISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQS 737
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 543 LYGDVDSPLP-TGEAGGPPSTREAELKLRLklvEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPT 621
Cdd:TIGR00606 738 IIDLKEKEIPeLRNKLQKVNRDIQRLKNDI---EEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAK 814
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 622 SPFGDSLESSTELRrhlQFVEEEAELLRRSISEIE-------DHNRQLTHELSKFKfepprepgwlgegaspgagggapl 694
Cdd:TIGR00606 815 LQGSDLDRTVQQVN---QEKQEKQHELDTVVSKIElnrkliqDQQEQIQHLKSKTN------------------------ 867
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 695 qeELKSARLQISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRAPSPRDSDAESDAGKKE----SDGEESRLPQPKREg 770
Cdd:TIGR00606 868 --ELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEelisSKETSNKKAQDKVN- 944
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 771 pvggesDSEEMFEKTSGFGSGKPSEASEPCPTELL-KAREDSEYLVTLKHEAQRLERTVERLITDTDSFlhdaglrggap 849
Cdd:TIGR00606 945 ------DIKEKVKNIHGYMKDIENKIQDGKDDYLKqKETELNTVNAQLEECEKHQEKINEDMRLMRQDI----------- 1007
|
570 580 590 600
....*....|....*....|....*....|....*....|....*.
gi 2217316421 850 lpgpglqGEEEQGEGDQQEPQLLGTINAKMKAFKKELQAFLEQVNR 895
Cdd:TIGR00606 1008 -------DTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQ 1046
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
86-218 |
6.80e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 47.75 E-value: 6.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 86 PSPGSLAAPGRLSRRSGGVPGAKDKPPPGagaraaggakaalgSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRG 165
Cdd:PRK14959 373 PSGGGASAPSGSAAEGPASGGAATIPTPG--------------TQGPQGTAPAAGMTPSSAAPATPAPSAAPSPRVPWDD 438
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2217316421 166 SRAPPARTVGPPTPAARIPavtlAVTSVAGSPARCSRISHTDSSSDLSDCPSE 218
Cdd:PRK14959 439 APPAPPRSGIPPRPAPRMP----EASPVPGAPDSVASASDAPPTLGDPSDTAE 487
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
55-261 |
7.33e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.95 E-value: 7.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 55 RPAAPGPAVPSSGRAPAPAAprspnlAGKAPPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAAR 134
Cdd:PRK12323 359 RMLAFRPGQSGGGAGPATAA------AAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEA 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 135 VAPAEPLSRAGKPPGAEPPSAAAkgrkakrgsrAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSS--SDL 212
Cdd:PRK12323 433 LAAARQASARGPGGAPAPAPAPA----------AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPpwEEL 502
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2217316421 213 SDCPSEPLSDEQRLLPA-ASSDAESGTGSSDREPPRGAPTPSPAARGAPP 261
Cdd:PRK12323 503 PPEFASPAPAQPDAAPAgWVAESIPDPATADPDDAFETLAPAPAAAPAPR 552
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
374-551 |
8.48e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.07 E-value: 8.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 374 YQLQELRRELDRANKNCRILQYRLRKAEQKslkvaetgqvdgelIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDEN 453
Cdd:COG1579 10 LDLQELDSELDRLEHRLKELPAELAELEDE--------------LAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 454 ETLRQQMIEVEISK--QALQNELERLKesslKRRSTRE------MYK-EKKtfnQDDSADLRCQLQFAKEEaflMRKKMA 524
Cdd:COG1579 76 KKYEEQLGNVRNNKeyEALQKEIESLK----RRISDLEdeilelMERiEEL---EEELAELEAELAELEAE---LEEKKA 145
|
170 180 190
....*....|....*....|....*....|.
gi 2217316421 525 KLGREKDELEQELQKYKS----LYGDVDSPL 551
Cdd:COG1579 146 ELDEELAELEAELEELEAereeLAAKIPPEL 176
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
351-603 |
9.67e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.83 E-value: 9.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 351 KDELDELRaEMEEMRDSyleEDVYQLQELRRELDRANKNCRILQyRLRKAEQK------------------SLKVAETGQ 412
Cdd:PTZ00121 1545 KKKADELK-KAEELKKA---EEKKKAEEAKKAEEDKNMALRKAE-EAKKAEEArieevmklyeeekkmkaeEAKKAEEAK 1619
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 413 VDGELIRSLEQDLKVAKDVSVRLHHELKTVEEKRaKAEDENETLRQQMI--EVEISKQALQ----NELERLKESSLKRRS 486
Cdd:PTZ00121 1620 IKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELK-KAEEENKIKAAEEAkkAEEDKKKAEEakkaEEDEKKAAEALKKEA 1698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 487 trEMYKEKKTFNQDDSADLRCQLQFAKEEaflmRKKMAKLGREKDELEQELQKYKSLYGDvdsplpTGEaggppSTREAE 566
Cdd:PTZ00121 1699 --EEAKKAEELKKKEAEEKKKAEELKKAE----EENKIKAEEAKKEAEEDKKKAEEAKKD------EEE-----KKKIAH 1761
|
250 260 270
....*....|....*....|....*....|....*..
gi 2217316421 567 LKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMR 603
Cdd:PTZ00121 1762 LKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
431-662 |
1.08e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.37 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 431 VSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQLQ 510
Cdd:TIGR02169 668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 511 FAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDV-----DSPLPTGEAGG----------PPSTREAELKLRLKLVE 575
Cdd:TIGR02169 748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELskleeevsriEARLREIEQKLNRLTLE 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 576 EEanILGRKIVELEVENRGLKaEMEDMRGQQEREGPGRdhapsiptspFGDSLESSTELRRHLQFVEEEAELLRRSISEI 655
Cdd:TIGR02169 828 KE--YLEKEIQELQEQRIDLK-EQIKSIEKEIENLNGK----------KEELEEELEELEAALRDLESRLGDLKKERDEL 894
|
....*..
gi 2217316421 656 EDHNRQL 662
Cdd:TIGR02169 895 EAQLREL 901
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
350-494 |
1.12e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.69 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDG---ElIRSLEQDLK 426
Cdd:COG1579 29 LPAELAELEDELAALEARLEAAKT-ELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEAlqkE-IESLKRRIS 106
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316421 427 VAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVeisKQALQNELERLKESSLKRRSTREMYKEK 494
Cdd:COG1579 107 DLEDEILELMERIEELEEELAELEAELAELEAELEEK---KAELDEELAELEAELEELEAEREELAAK 171
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
350-609 |
1.26e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 46.06 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEM---RDSY---LEEDVYQLQELRRELDRANKNCRILqyrlrKAEQKSLKvAETGQVDGELirsleQ 423
Cdd:COG1340 27 LKEKRDELNEELKELaekRDELnaqVKELREEAQELREKRDELNEKVKEL-----KEERDELN-EKLNELREEL-----D 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 424 DLKVAKDVSVRLHHELKTVEEKRAKAEDENET------LRQQMIEvEISKqaLQNELERLKESSLKRRSTREMYKEKKTF 497
Cdd:COG1340 96 ELRKELAELNKAGGSIDKLRKEIERLEWRQQTevlspeEEKELVE-KIKE--LEKELEKAKKALEKNEKLKELRAELKEL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 498 nQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYgdvdsplptgeaggppstreAELKLRLKLVEEE 577
Cdd:COG1340 173 -RKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEI--------------------VEAQEKADELHEE 231
|
250 260 270
....*....|....*....|....*....|..
gi 2217316421 578 ANILGRKIVELEVENRGLKAEMEDMRGQQERE 609
Cdd:COG1340 232 IIELQKELRELRKELKKLRKKQRALKREKEKE 263
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
359-670 |
1.33e-04 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 47.38 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 359 AEMEEMRDSYLEEDVYQLQE------LRRELDRANKNCRILQ--------YRLRKAEQKSL-------------KVAETG 411
Cdd:COG5022 734 AALEDMRDAKLDNIATRIQRairgryLRRRYLQALKRIKKIQviqhgfrlRRLVDYELKWRlfiklqpllsllgSRKEYR 813
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 412 QVDgELIRSLEQDLKVAKDVSVRLHHELKTVEE-------------KRAKAEDENETLRQQMIEVEISK---QALQNELE 475
Cdd:COG5022 814 SYL-ACIIKLQKTIKREKKLRETEEVEFSLKAEvliqkfgrslkakKRFSLLKKETIYLQSAQRVELAErqlQELKIDVK 892
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 476 RLKESSLKRRSTREMYKEkktFNQDDSADLRCQLQFaKEEAFLMRKKMAKLGREKDELEQELQKYKSLygdvdsplptge 555
Cdd:COG5022 893 SISSLKLVNLELESEIIE---LKKSLSSDLIENLEF-KTELIARLKKLLNNIDLEEGPSIEYVKLPEL------------ 956
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 556 aggppstreaelklrLKLVEEEANiLGRKIVELEVENRGLKAEMEDMRGQQERegpgrdhapsipTSPFGDSLESSTELR 635
Cdd:COG5022 957 ---------------NKLHEVESK-LKETSEEYEDLLKKSTILVREGNKANSE------------LKNFKKELAELSKQY 1008
|
330 340 350
....*....|....*....|....*....|....*
gi 2217316421 636 RHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFK 670
Cdd:COG5022 1009 GALQESTKQLKELPVEVAELQSASKIISSESTELS 1043
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
398-656 |
1.48e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 46.43 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 398 RKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERL 477
Cdd:COG4372 6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 478 KEsSLKRRstremykekktfnQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLptgeag 557
Cdd:COG4372 86 NE-QLQAA-------------QAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEI------ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 558 gppSTREAELK-LRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLESSTELRR 636
Cdd:COG4372 146 ---AEREEELKeLEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLE 222
|
250 260
....*....|....*....|
gi 2217316421 637 HLQFVEEEAELLRRSISEIE 656
Cdd:COG4372 223 AKDSLEAKLGLALSALLDAL 242
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
345-657 |
1.53e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.09 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 345 SENDYLKDELDEL-RAEME-EMRDSYLEEdvyQLQELRRELDRANKNCRILQYRLRKAEqkslkvAETGQVDGELIRSLE 422
Cdd:pfam01576 384 SENAELQAELRTLqQAKQDsEHKRKKLEG---QLQELQARLSESERQRAELAEKLSKLQ------SELESVSSLLNEAEG 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 423 QDLKVAKDVSvRLHHELKTV-----EEKRAK---------AEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRR- 485
Cdd:pfam01576 455 KNIKLSKDVS-SLESQLQDTqellqEETRQKlnlstrlrqLEDERNSLQEQLEEEEEAKRNVERQLSTLQAqlSDMKKKl 533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 486 ----STREMYKEKKTFNQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDV-------DSPLPTG 554
Cdd:pfam01576 534 eedaGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLekkqkkfDQMLAEE 613
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 555 EAGGPPSTRE---AELKLRLKlvEEEANILGR-------KIVELEVENRGLKAEMEDMRGQQEREGpgrdhapsiptspf 624
Cdd:pfam01576 614 KAISARYAEErdrAEAEAREK--ETRALSLARaleealeAKEELERTNKQLRAEMEDLVSSKDDVG-------------- 677
|
330 340 350
....*....|....*....|....*....|...
gi 2217316421 625 gdslESSTELRRHLQFVEEEAELLRRSISEIED 657
Cdd:pfam01576 678 ----KNVHELERSKRALEQQVEEMKTQLEELED 706
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
82-326 |
1.70e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.09 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 82 GKAPPSPGSLAAPGRLSRRSGGvPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAG-------KPPGAEPPS 154
Cdd:PHA03307 69 TGPPPGPGTEAPANESRSTPTW-SLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPApdlsemlRPVGSPGPP 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 155 AAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAG----SPARCSRISHTDSSSDLSDcPSEPLSDEQRLLPAA 230
Cdd:PHA03307 148 PAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSppaePPPSTPPAAASPRPPRRSS-PISASASSPAPAPGR 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 231 SSDAESGTGSSDREPPRGAPTPSpAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPgvaedvRGRSPPer 310
Cdd:PHA03307 227 SAADDAGASSSDSSSSESSGCGW-GPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSP------RERSPS-- 297
|
250
....*....|....*.
gi 2217316421 311 PVPGTPKEPSLGEQSR 326
Cdd:PHA03307 298 PSPSSPGSGPAPSSPR 313
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
350-479 |
1.71e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 46.39 E-value: 1.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYL--EEDVYQLQELRRELDRANKNCRILQYRLRKAEQ-------------KSLKVAETGQVD 414
Cdd:pfam06160 303 AEEQNKELKEELERVQQSYTlnENELERVRGLEKQLEELEKRYDEIVERLEEKEVayselqeeleeilEQLEEIEEEQEE 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 415 G-ELIRSLEQDLKVAKDVSVRLHHELKTVE---EKR-------------AKAEDENETLRQQMIEV-----EISKQAL-- 470
Cdd:pfam06160 383 FkESLQSLRKDELEAREKLDEFKLELREIKrlvEKSnlpglpesyldyfFDVSDEIEDLADELNEVplnmdEVNRLLDea 462
|
....*....
gi 2217316421 471 QNELERLKE 479
Cdd:pfam06160 463 QDDVDTLYE 471
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
345-660 |
1.75e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.57 E-value: 1.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 345 SENDYLKDELDELRAEME---EMRDSyLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSL 421
Cdd:PRK02224 213 SELAELDEEIERYEEQREqarETRDE-ADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEEL 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKktfnqdd 501
Cdd:PRK02224 292 EEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREE------- 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 502 SADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELqkykslygdvdsplptgeaGGPPSTREaELKLRLKLVEEEANIL 581
Cdd:PRK02224 365 AAELESELEEAREAVEDRREEIEELEEEIEELRERF-------------------GDAPVDLG-NAEDFLEELREERDEL 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 582 GRKIVELEVENRGLKAEMEDMRGQQErEGPGRDHAPSIPTSPFGDSLESSTELRRHLqfvEEEAELLRRSISEIED-HNR 660
Cdd:PRK02224 425 REREAELEATLRTARERVEEAEALLE-AGKCPECGQPVEGSPHVETIEEDRERVEEL---EAELEDLEEEVEEVEErLER 500
|
|
| DUF4201 |
pfam13870 |
Domain of unknown function (DUF4201); This is a family of coiled-coil proteins from eukaryotes. ... |
376-539 |
1.76e-04 |
|
Domain of unknown function (DUF4201); This is a family of coiled-coil proteins from eukaryotes. The function is not known.
Pssm-ID: 464008 [Multi-domain] Cd Length: 177 Bit Score: 44.52 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 376 LQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQ----VD-----------GELIRSLEQDLKVAKDVSVRLHHELK 440
Cdd:pfam13870 1 MRAKRNELSKLRLELITLKHTLAKIQEKLEQKEELGEgltmIDflqlqienqalNEKIEERNKELKRLKLKVTNTVHALT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 441 TVEEKRAKAEDENETLRQQMIEveisKQALQNELErlkesslkrrstREMYKEKKTFNQ--DDSADLRCQL--------- 509
Cdd:pfam13870 81 HLKEKLHFLSAELSRLKKELRE----RQELLAKLR------------KELYRVKLERDKlrKQNKKLRQQGgllhvpall 144
|
170 180 190
....*....|....*....|....*....|...
gi 2217316421 510 -QFAKEEAFL--MRKKMAKLGREKDELEQELQK 539
Cdd:pfam13870 145 hDYDKTKAEVeeKRKSVKKLRRKVKILEMRIKE 177
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
350-512 |
1.94e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.59 E-value: 1.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVA- 428
Cdd:TIGR02168 356 LEAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAe 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 429 -KDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRC 507
Cdd:TIGR02168 435 lKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN 514
|
....*
gi 2217316421 508 QLQFA 512
Cdd:TIGR02168 515 QSGLS 519
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
345-543 |
2.02e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 45.67 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 345 SENDYLKDELDELRAEMEEMRDSYLE---------EDVYQLQELRRELDRANKNCRILQYRLRKAEQKSlkvaETGQVDG 415
Cdd:COG1340 57 EEAQELREKRDELNEKVKELKEERDElneklnelrEELDELRKELAELNKAGGSIDKLRKEIERLEWRQ----QTEVLSP 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 416 EL-------IRSLEQDLKVAKDvSVRLHHELKTVEEKRAKAEDENETLRQQMIEV--EISK-----QALQNELERLKESS 481
Cdd:COG1340 133 EEekelvekIKELEKELEKAKK-ALEKNEKLKELRAELKELRKEAEEIHKKIKELaeEAQElheemIELYKEADELRKEA 211
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316421 482 -------LKRRSTREMYKEKKTFNQDDSADLRCQL--QFAKEEAFLMRKKMAKLGREKDELEQELQKYKSL 543
Cdd:COG1340 212 delhkeiVEAQEKADELHEEIIELQKELRELRKELkkLRKKQRALKREKEKEELEEKAEEIFEKLKKGEKL 282
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
12-265 |
2.34e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 12 APDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPflkdlhARPAAPGPAVPSSGRapapaAPRSPNLAGKAPPSPGSL 91
Cdd:PRK07764 589 GPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAP------AAPAPAGAAAAPAEA-----SAAPAPGVAAPEHHPKHV 657
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 92 AAPGRLSRRSGGVPGAKDKPPPgagaraaggakaalgsrrAARVAPAEPLSRAGKPPGAEPPSAAAKGRKAKRGSRAPPA 171
Cdd:PRK07764 658 AVPDASDGGDGWPAKAGGAAPA------------------APPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAA 719
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 172 RTVGPPTPAARIPAVTLAVTSVAGSParcsrishtdsssDLSDCPSEPLSDEQrllPAASSDAESGTGSSDREPPRGAPT 251
Cdd:PRK07764 720 QPPQAAQGASAPSPAADDPVPLPPEP-------------DDPPDPAGAPAQPP---PPPAPAPAAAPAAAPPPSPPSEEE 783
|
250
....*....|....
gi 2217316421 252 PSPAARGAPPGSPE 265
Cdd:PRK07764 784 EMAEDDAPSMDDED 797
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
349-544 |
2.48e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.16 E-value: 2.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 349 YLKDELDELRAEMEEMRDsYLEEdvyQLQELRRELDRANKncRILQYRlrkAEQKSLKVAETGQVDGELIRSLEQDLKVA 428
Cdd:COG3206 161 YLEQNLELRREEARKALE-FLEE---QLPELRKELEEAEA--ALEEFR---QKNGLVDLSEEAKLLLQQLSELESQLAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 429 KDVSVRLHHELKTVEEKRAKAEDEN---------ETLRQQMIEVEISK--------------QALQNELERLKESSLKR- 484
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALpellqspviQQLRAQLAELEAELaelsarytpnhpdvIALRAQIAALRAQLQQEa 311
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 485 RSTREMYKEKKTFNQDDSADLRCQLQFAKEEAflmrKKMAKLGREKDELEQELQKYKSLY 544
Cdd:COG3206 312 QRILASLEAELEALQAREASLQAQLAQLEARL----AELPELEAELRRLEREVEVARELY 367
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
131-264 |
2.54e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 2.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 131 RAARVAPAEPLSRAGKPPGAEPPSAAAkgrkAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSS 210
Cdd:PRK07764 377 RLERLERRLGVAGGAGAPAAAAPSAAA----AAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGG 452
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2217316421 211 DLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSP 264
Cdd:PRK07764 453 APSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGA 506
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
144-264 |
2.61e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 45.86 E-value: 2.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 144 AGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTL-AVTSVAGSPArcSRISHTDSSSDLSDCPSEPLSD 222
Cdd:PRK14951 363 AFKPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPaAAASAPAAPP--AAAPPAPVAAPAAAAPAAAPAA 440
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2217316421 223 EQRLLPAASSDAESGTGSSDREPPRGAPTPSPA-ARGAPPGSP 264
Cdd:PRK14951 441 APAAVALAPAPPAQAAPETVAIPVRVAPEPAVAsAAPAPAAAP 483
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
13-319 |
3.36e-04 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 45.44 E-value: 3.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 13 PDAKLQPPGQHHRHHHLHPVAERrrLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLA 92
Cdd:COG5180 158 SDPILAKDPDGDSASTLPPPAEK--LDKVLTEPRDALKDSPEKLDRPKVEVKDEAQEEPPDLTGGADHPRPEAASSPKVD 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 93 APGRLSRRSGgvPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAA-AKGRKAKRGSRAPPA 171
Cdd:COG5180 236 PPSTSEARSR--PATVDAQPEMRPPADAKERRRAAIGDTPAAEPPGLPVLEAGSEPQSDAPEAEtARPIDVKGVASAPPA 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 172 RTVGPPTPAAR---IPAVTLAVTSVAGSPARCSRISHTDSSSDlsdcPSEPLSDEQRLLPAASSDAESGTGSSDREPPRG 248
Cdd:COG5180 314 TRPVRPPGGARdpgTPRPGQPTERPAGVPEAASDAGQPPSAYP----PAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNG 389
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316421 249 APTPSPaARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAedvrgRSPPERPVPGTPKEP 319
Cdd:COG5180 390 APQPGL-GRRGAPGPPMGAGDLVQAALDGGGRETASLGGAAGGAGQGPKAD-----FVPGDAESVSGPAGL 454
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
323-662 |
3.52e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.50 E-value: 3.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 323 EQSRLvpAAEEEELLREMEELRSendyLKDELDELRAEMEEMRDSYLEEDVYQLqELRRELDRankncriLQYRLRKAEQ 402
Cdd:pfam17380 297 EQERL--RQEKEEKAREVERRRK----LEEAEKARQAEMDRQAAIYAEQERMAM-ERERELER-------IRQEERKREL 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 403 KSLKVAETGqVDGELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEI----SKQALQNELERLK 478
Cdd:pfam17380 363 ERIRQEEIA-MEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQiraeQEEARQREVRRLE 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 479 EsslKRRSTREMYKEKKTFNQDDSADLRcqlqfaKEEAFLMRKKMAKLGREKDELEQELQKYKSLygdvdsplptgeagg 558
Cdd:pfam17380 442 E---ERAREMERVRLEEQERQQQVERLR------QQEEERKRKKLELEKEKRDRKRAEEQRRKIL--------------- 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 559 ppstrEAELKLRLKLVEEEANilGRKIVELEVENRGLKAEMEDMRGQQEREgpGRDHAPSIPTSPFGDSLESSTELRRHL 638
Cdd:pfam17380 498 -----EKELEERKQAMIEEER--KRKLLEKEMEERQKAIYEEERRREAEEE--RRKQQEMEERRRIQEQMRKATEERSRL 568
|
330 340
....*....|....*....|....
gi 2217316421 639 QFVEEEAELLRRsISEIEDHNRQL 662
Cdd:pfam17380 569 EAMEREREMMRQ-IVESEKARAEY 591
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
102-323 |
3.98e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 3.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 102 GGVPGAKDKPPPGAGARAAGGAKAalgSRRAARVAPAEPlSRAGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAA 181
Cdd:PRK07764 589 GPAPGAAGGEGPPAPASSGPPEEA---ARPAAPAAPAAP-AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 182 RIPAVTLAVTSVAGSParcsrishtdsssdlsdcPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPP 261
Cdd:PRK07764 665 GGDGWPAKAGGAAPAA------------------PPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQ 726
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217316421 262 GSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGE 323
Cdd:PRK07764 727 GASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAED 788
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
351-538 |
4.51e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.42 E-value: 4.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 351 KDELDELRAEMEEMRDSY------LEEDVYQLQELRRELDRANK-------NCRILQYRLRKAEQ--KSLKVAETGQ--- 412
Cdd:PRK02224 383 REEIEELEEEIEELRERFgdapvdLGNAEDFLEELREERDELREreaeleaTLRTARERVEEAEAllEAGKCPECGQpve 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 413 ----VDG-----ELIRSLEQDLKVAKDVSVRLHHELKTVEEKrAKAEDENETLRQQmieVEISKQALQNELERLKESSLK 483
Cdd:PRK02224 463 gsphVETieedrERVEELEAELEDLEEEVEEVEERLERAEDL-VEAEDRIERLEER---REDLEELIAERRETIEEKRER 538
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2217316421 484 RRSTREMYKEKKTfnqdDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQ 538
Cdd:PRK02224 539 AEELRERAAELEA----EAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE 589
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
352-496 |
4.58e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.52 E-value: 4.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 352 DELDELRAEMEEMRDsylEEDVYQLQELRRELDRANKNCRILQyrlRKAEQKSlKVAETGQVDGELIRSLEQDLKVAKDV 431
Cdd:PTZ00121 1656 EEENKIKAAEEAKKA---EEDKKKAEEAKKAEEDEKKAAEALK---KEAEEAK-KAEELKKKEAEEKKKAEELKKAEEEN 1728
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217316421 432 SVRLHHELKTVEEKRAKAE----DENETLRQQMIEVEISKQALQNELER---LKESSLKRRSTREMYKEKKT 496
Cdd:PTZ00121 1729 KIKAEEAKKEAEEDKKKAEeakkDEEEKKKIAHLKKEEEKKAEEIRKEKeavIEEELDEEDEKRRMEVDKKI 1800
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
149-331 |
5.77e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.87 E-value: 5.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 149 GAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRishtdsssdlsdcpsePLSDEQRLLP 228
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPA----------------RRSPAPEALA 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 229 AASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPE------PPALLAAPLAAGAcPGGRSIP--SGVSGGFAGPGVAE 300
Cdd:PRK12323 435 AARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPvaaaaaAAPARAAPAAAPA-PADDDPPpwEELPPEFASPAPAQ 513
|
170 180 190
....*....|....*....|....*....|....
gi 2217316421 301 DVRGRSPPER---PVPGTPKEPSLGEQSRLVPAA 331
Cdd:PRK12323 514 PDAAPAGWVAesiPDPATADPDDAFETLAPAPAA 547
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
130-313 |
6.70e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.78 E-value: 6.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 130 RRAARVAPAEPLSRA-GKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDS 208
Cdd:PHA03307 742 RRARARASAWDITDAlFSNPSLVPAKLAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRKS 821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 209 SSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSG 288
Cdd:PHA03307 822 RSHTPDGGSESSGPARPPGAAARPPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAP 901
|
170 180
....*....|....*....|....*
gi 2217316421 289 VSggfAGPGVAEDVRGRSPPERPVP 313
Cdd:PHA03307 902 AP---RPRPAPRVKLGPMPPGGPDP 923
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
348-516 |
6.92e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 6.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 348 DYLKDELDELRAEMEEMRDSY-----LEEDVYQLQ----ELRRELDRANKNCRILQYRLRKAEQ-----KSLKVAETGQV 413
Cdd:COG4913 664 ASAEREIAELEAELERLDASSddlaaLEEQLEELEaeleELEEELDELKGEIGRLEKELEQAEEeldelQDRLEAAEDLA 743
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 414 DGELIRSLEQDL------KVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQ--------MIEVEISKQAL---QNELER 476
Cdd:COG4913 744 RLELRALLEERFaaalgdAVERELRENLEERIDALRARLNRAEEELERAMRAfnrewpaeTADLDADLESLpeyLALLDR 823
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2217316421 477 LKESSLKRRsTREMYKEKKTFNQDDSADLRCQLQFAKEEA 516
Cdd:COG4913 824 LEEDGLPEY-EERFKELLNENSIEFVADLLSKLRRAIREI 862
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
416-627 |
8.14e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 8.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 416 ELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLK-------------ESSL 482
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelaelekeiaelRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 483 KRRST------REMYKEKKT------FNQDDSAD-------LRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSL 543
Cdd:COG4942 100 EAQKEelaellRALYRLGRQpplallLSPEDFLDavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 544 YGDVdsplptgeaggppSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQER-EGPGRDHAPSIPTS 622
Cdd:COG4942 180 LAEL-------------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARlEAEAAAAAERTPAA 246
|
....*
gi 2217316421 623 PFGDS 627
Cdd:COG4942 247 GFAAL 251
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
348-714 |
8.44e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 44.51 E-value: 8.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 348 DYLKDELDELRAEMEEMrdSYLEEDVY----QLQELRRELDRANKNCRILqyrLRKAEQKSlkvAETGQVDGELI--RSL 421
Cdd:PRK01156 169 DKLKDVIDMLRAEISNI--DYLEEKLKssnlELENIKKQIADDEKSHSIT---LKEIERLS---IEYNNAMDDYNnlKSA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENetlrqqmieVEISkqALQNELERLKESSL--KRRSTREMYKEKKTFNQ 499
Cdd:PRK01156 241 LNELSSLEDMKNRYESEIKTAESDLSMELEKN---------NYYK--ELEERHMKIINDPVykNRNYINDYFKYKNDIEN 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 500 ---------------DDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDS--------------- 549
Cdd:PRK01156 310 kkqilsnidaeinkyHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESlkkkieeysknierm 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 550 PLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGpGRDHAPSIPTSpFGDslE 629
Cdd:PRK01156 390 SAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLN-GQSVCPVCGTT-LGE--E 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 630 SSTELRRH----LQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREpgwlgegASPGAGGGAPLQEELKSARLQI 705
Cdd:PRK01156 466 KSNHIINHynekKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINK-------SINEYNKIESARADLEDIKIKI 538
|
....*....
gi 2217316421 706 SELSGKVLK 714
Cdd:PRK01156 539 NELKDKHDK 547
|
|
| BAR |
cd07307 |
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects ... |
376-587 |
8.67e-04 |
|
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; BAR domains are dimerization, lipid binding and curvature sensing modules found in many different proteins with diverse functions including organelle biogenesis, membrane trafficking or remodeling, and cell division and migration. Mutations in BAR containing proteins have been linked to diseases and their inactivation in cells leads to altered membrane dynamics. A BAR domain with an additional N-terminal amphipathic helix (an N-BAR) can drive membrane curvature. These N-BAR domains are found in amphiphysins and endophilins, among others. BAR domains are also frequently found alongside domains that determine lipid specificity, such as the Pleckstrin Homology (PH) and Phox Homology (PX) domains which are present in beta centaurins (ACAPs and ASAPs) and sorting nexins, respectively. A FES-CIP4 Homology (FCH) domain together with a coiled coil region is called the F-BAR domain and is present in Pombe/Cdc15 homology (PCH) family proteins, which include Fes/Fes tyrosine kinases, PACSIN or syndapin, CIP4-like proteins, and srGAPs, among others. The Inverse (I)-BAR or IRSp53/MIM homology Domain (IMD) is found in multi-domain proteins, such as IRSp53 and MIM, that act as scaffolding proteins and transducers of a variety of signaling pathways that link membrane dynamics and the underlying actin cytoskeleton. BAR domains form dimers that bind to membranes, induce membrane bending and curvature, and may also be involved in protein-protein interactions. The I-BAR domain induces membrane protrusions in the opposite direction compared to classical BAR and F-BAR domains, which produce membrane invaginations. BAR domains that also serve as protein interaction domains include those of arfaptin and OPHN1-like proteins, among others, which bind to Rac and Rho GAP domains, respectively.
Pssm-ID: 153271 [Multi-domain] Cd Length: 194 Bit Score: 42.43 E-value: 8.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 376 LQELRRELDRANKNCRILQYRLRKAEQKSLKVAEtgqvdgelirSLEqdlKVAKDVSVRLHHELKTVEEKRAKAEDENET 455
Cdd:cd07307 2 LDELEKLLKKLIKDTKKLLDSLKELPAAAEKLSE----------ALQ---ELGKELPDLSNTDLGEALEKFGKIQKELEE 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 456 LRQQMIE------VEISKQALQNELERLKESSLKRRSTREMYkekktfnqdDSAdlrcqlqFAKEEAflMRKKMAKLGRE 529
Cdd:cd07307 69 FRDQLEQklenkvIEPLKEYLKKDLKEIKKRRKKLDKARLDY---------DAA-------REKLKK--LRKKKKDSSKL 130
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316421 530 KdELEQELQKYKSLYGDVdsplptgeaggppstrEAELKLRLKLVEEEANILGRKIVE 587
Cdd:cd07307 131 A-EAEEELQEAKEKYEEL----------------REELIEDLNKLEEKRKELFLSLLL 171
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
338-672 |
9.41e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 44.28 E-value: 9.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 338 REMEELRSENDYLKDELDELRAEMEEMRDS---------YLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVA 408
Cdd:PRK03918 262 RELEERIEELKKEIEELEEKVKELKELKEKaeeyiklseFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 409 ETgqvdGELIRSLEQDLKVAKDvSVRLHHELKTVEE-----KRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SS 481
Cdd:PRK03918 342 EL----KKKLKELEKRLEELEE-RHELYEEAKAKKEelerlKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITAriGE 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 482 LKRRSTRemykEKKTFNQDDSADLRCQLQFA----KEEAFLMRK---KMAKLGREKDELEQELQKYKSLYGDVDSPLptg 554
Cdd:PRK03918 417 LKKEIKE----LKKAIEELKKAKGKCPVCGRelteEHRKELLEEytaELKRIEKELKEIEEKERKLRKELRELEKVL--- 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 555 eAGGPPSTREAELKLRLKLVEEEANILGRKIVELEVEN-RGLKAEMEDMRGQQERegpgrdhapsiptspFGDSLESSTE 633
Cdd:PRK03918 490 -KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEyEKLKEKLIKLKGEIKS---------------LKKELEKLEE 553
|
330 340 350
....*....|....*....|....*....|....*....
gi 2217316421 634 LrrhlqfvEEEAELLRRSISEIEDHNRQLTHELSKFKFE 672
Cdd:PRK03918 554 L-------KKKLAELEKKLDELEEELAELLKELEELGFE 585
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
344-671 |
9.84e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 44.24 E-value: 9.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 344 RSENDYLKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDranKNCRILQ--YRLRKAEQKSLKVAETGQvdGELIRSL 421
Cdd:TIGR04523 376 KKENQSYKQEIKNLESQIND-----LESKIQNQEKLNQQKD---EQIKKLQqeKELLEKEIERLKETIIKN--NSEIKDL 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 422 EQDLKVAKdvsvrlhhelKTVEEKRAKAEDENETLRQQMIEVEISKQALQN---ELERlKESSLKrrstreMYKEKKTfn 498
Cdd:TIGR04523 446 TNQDSVKE----------LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQkqkELKS-KEKELK------KLNEEKK-- 506
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 499 qddsaDLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELqkyKSLYGDVDsplptgeaggppstreaELKLRLK--LVEE 576
Cdd:TIGR04523 507 -----ELEEKVKDLTKKISSLKEKIEKLESEKKEKESKI---SDLEDELN-----------------KDDFELKkeNLEK 561
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 577 EANILGRKIVELEVENRGLKA---EMEDMRGQQEREgpgrdhapsiptspfgdslesSTELRRHLQFVEEEAELLRRSIS 653
Cdd:TIGR04523 562 EIDEKNKEIEELKQTQKSLKKkqeEKQELIDQKEKE---------------------KKDLIKEIEEKEKKISSLEKELE 620
|
330
....*....|....*...
gi 2217316421 654 EIEDHNRQLTHELSKFKF 671
Cdd:TIGR04523 621 KAKKENEKLSSIIKNIKS 638
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
392-769 |
1.14e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.28 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 392 ILQYRLRK--AEQKslkvaetgqvdgelIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENEtLRQQMIEVEIS--- 466
Cdd:TIGR02168 167 ISKYKERRkeTERK--------------LERTRENLDRLEDILNELERQLKSLERQAEKAERYKE-LKAELRELELAllv 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 467 --KQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLY 544
Cdd:TIGR02168 232 lrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 545 GDVDSPLPTGEAggppstREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEregpgrdhapsiptspf 624
Cdd:TIGR02168 312 ANLERQLEELEA------QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE----------------- 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 625 gdslesstELRRHLQFVEEEAELLRRSISEiedhnrqlthelskfkfepprepgwlgegaspgagggapLQEELKSARLQ 704
Cdd:TIGR02168 369 --------ELESRLEELEEQLETLRSKVAQ---------------------------------------LELQIASLNNE 401
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217316421 705 ISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRAPSPRDSdAESDAGKKESDGEESRLPQPKRE 769
Cdd:TIGR02168 402 IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL-EELEEELEELQEELERLEEALEE 465
|
|
| Rootletin |
pfam15035 |
Ciliary rootlet component, centrosome cohesion; |
391-493 |
1.27e-03 |
|
Ciliary rootlet component, centrosome cohesion;
Pssm-ID: 464459 [Multi-domain] Cd Length: 190 Bit Score: 41.95 E-value: 1.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 391 RILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDL-----KVAKDVSVRLHHELKTVEEKRAKAED---ENETLRQQMIE 462
Cdd:pfam15035 24 KVLQYKKRCSELEQQLLEKTSELEKTELLLRKLTLeprlqRLEREHSADLEEALIRLEEERQRSESlsqVNSLLREQLEQ 103
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2217316421 463 VEISKQALQNELERL-------------KESSLKRRstREMYKE 493
Cdd:pfam15035 104 ASRANEALREDLQKLtndwerareeleqKESEWRKE--EEAFNE 145
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
499-728 |
1.29e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.21 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 499 QDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVdsplptgeaggppSTREAELKLRLKLVEEEA 578
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL-------------ARRIRALEQELAALEAEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 579 NILGRKIVELEVENRGLKAEMEDMRGQQEREgpGRDHAPSIPTSP--FGDSLESSTELRRHLQFVEEEAELLRRSISEIE 656
Cdd:COG4942 86 AELEKEIAELRAELEAQKEELAELLRALYRL--GRQPPLALLLSPedFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217316421 657 DHNRQLTHELSKfkfepprepgwLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQR 728
Cdd:COG4942 164 ALRAELEAERAE-----------LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
340-607 |
1.33e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 340 MEELRSENDYLKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKsLKVAETGQVDGELIR 419
Cdd:COG4717 165 LEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE-LEQLENELEAAALEE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 420 SLEQDLKVAKDVSVRL------------------------------------HHELKTVEEKRAKAEDENETLRQQMIEV 463
Cdd:COG4717 244 RLKEARLLLLIAAALLallglggsllsliltiagvlflvlgllallflllarEKASLGKEAEELQALPALEELEEEELEE 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 464 EISKQALQNELERLKESSLKRRSTRemYKEKKTFNQDDSADLRCQLQFAKEEAFLMRKKM------AKLGREKDELEQEL 537
Cdd:COG4717 324 LLAALGLPPDLSPEELLELLDRIEE--LQELLREAEELEEELQLEELEQEIAALLAEAGVedeeelRAALEQAEEYQELK 401
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 538 QKYKSLYGDVDSPLPTGEAGGPPSTREaELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQE 607
Cdd:COG4717 402 EELEELEEQLEELLGELEELLEALDEE-ELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE 470
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
392-609 |
1.33e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 392 ILQYRLRKAEQKSLKV-AETGQVDGELIRSLEQDLKvakdvsvrlhhELKTVEEKRAKAEDENETLRQQMIEVEISKQAL 470
Cdd:COG4717 46 MLLERLEKEADELFKPqGRKPELNLKELKELEEELK-----------EAEEKEEEYAELQEELEELEEELEELEAELEEL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 471 QNELERLKesslKRRSTREMYKEKKTFNQDDsADLRCQLQFAKEEaflmRKKMAKLGREKDELEQELQKYKSLygdvdsp 550
Cdd:COG4717 115 REELEKLE----KLLQLLPLYQELEALEAEL-AELPERLEELEER----LEELRELEEELEELEAELAELQEE------- 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316421 551 LPTGEAGGPPSTREA--ELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERE 609
Cdd:COG4717 179 LEELLEQLSLATEEElqDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA 239
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
110-262 |
1.46e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 43.55 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 110 KPPPGAGaraaggakaalgsrrAARVAPAEPLSRAGKP-PGAEPPSAAAKGRKAKrgsRAPPARTVGPPTPAARI-PAVT 187
Cdd:PRK14951 365 KPAAAAE---------------AAAPAEKKTPARPEAAaPAAAPVAQAAAAPAPA---AAPAAAASAPAAPPAAApPAPV 426
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217316421 188 LAVTSVAGSPARcsriSHTDSSSDLSDCPSEPLSDEQRLLPAAssdAESGTGSSDREPPRGAPTPSPAARGAPPG 262
Cdd:PRK14951 427 AAPAAAAPAAAP----AAAPAAVALAPAPPAQAAPETVAIPVR---VAPEPAVASAAPAPAAAPAAARLTPTEEG 494
|
|
| KASH_CCD |
pfam14662 |
Coiled-coil region of CCDC155 or KASH; This coiled-coil region is found in the central part of ... |
418-598 |
1.50e-03 |
|
Coiled-coil region of CCDC155 or KASH; This coiled-coil region is found in the central part of KASH or Klarsicht/ANC-1/Syne/homology proteins. KASH are a meiosis-specific proteins that localize at telomeres and interact with SUN1, thus being implicated in meiotic chromosome dynamics and homolog pairing.
Pssm-ID: 405365 [Multi-domain] Cd Length: 191 Bit Score: 41.70 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 418 IRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMievEISKQALQNELE--------RLKESSLKRRSTRE 489
Cdd:pfam14662 10 VEDLQANNQKLLQENSKLKATVETREETNAKLLEENLNLRKQA---KSQQQAVQKEKLleeeledlKLIVNSLEEARRSL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 490 MYKEK-KTFNQDDSA----DLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDvdsplptgeaggppstRE 564
Cdd:pfam14662 87 LAQNKqLEKENQSLLqeieSLQEENKKNQAERDKLQKKKKELLKSKACLKEQLHSCEDLACN----------------RE 150
|
170 180 190
....*....|....*....|....*....|....
gi 2217316421 565 AELKLRLKLVEEEAnilgRKIVELEVENRGLKAE 598
Cdd:pfam14662 151 TILIEKTTQIEELK----STVEEYSSIEEELRAE 180
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
351-619 |
1.97e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.50 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 351 KDELDELR---AEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLkv 427
Cdd:TIGR00606 244 ENELDPLKnrlKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKEREL-- 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 428 akdvsVRLHHELKtveekraKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTRE------------------ 489
Cdd:TIGR00606 322 -----VDCQRELE-------KLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQslatrleldgfergpfse 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 490 -------------MYKEKKTFNQdDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEa 556
Cdd:TIGR00606 390 rqiknfhtlvierQEDEAKTAAQ-LCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLE- 467
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217316421 557 GGPPSTREAELKLR-----LKLVEEEANILGRKIVELEVEN------RGLKAEMEDMRgQQEREGPGRDHAPSI 619
Cdd:TIGR00606 468 GSSDRILELDQELRkaereLSKAEKNSLTETLKKEVKSLQNekadldRKLRKLDQEME-QLNHHTTTRTQMEML 540
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
434-601 |
1.97e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 434 RLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEK--KTFNQDDSADLRCQLQF 511
Cdd:COG1579 21 RLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQlgNVRNNKEYEALQKEIES 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 512 AKEEAFLMRKKMAKLGREKDELEQELQKYKSLYgdvdsplptgeaggppSTREAELKLRLKLVEEEANILGRKIVELEVE 591
Cdd:COG1579 101 LKRRISDLEDEILELMERIEELEEELAELEAEL----------------AELEAELEEKKAELDEELAELEAELEELEAE 164
|
170
....*....|
gi 2217316421 592 NRGLKAEMED 601
Cdd:COG1579 165 REELAAKIPP 174
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
350-487 |
2.09e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 2.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKncrilqyRLRKAEQKSLKVAETgqvDGELIRSLEQDLKvak 429
Cdd:COG3206 268 LRAQLAELEAELAELSARYTPNHP-DVIALRAQIAALRA-------QLQQEAQRILASLEA---ELEALQAREASLQ--- 333
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2217316421 430 dvsvrlhhelKTVEEKRAKAEDENETLRQQMI---EVEISKQALQNELERLKESSLKRRST 487
Cdd:COG3206 334 ----------AQLAQLEARLAELPELEAELRRlerEVEVARELYESLLQRLEEARLAEALT 384
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
347-600 |
2.12e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.29 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 347 NDYLKDELDELRAEMEEMRDSY--LEEDVYQ----LQELRRELDRAN---KNCRILQYRLrKAEQKSLKVAETGQVD--- 414
Cdd:pfam12128 599 EEELRERLDKAEEALQSAREKQaaAEEQLVQangeLEKASREETFARtalKNARLDLRRL-FDEKQSEKDKKNKALAerk 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 415 ---GELIRSLEQDLKVakdvsvrLHHELKTVEEKRAKAEDENETLRQQMIEVEISkqALQNELERLKESSLKRRSTREmy 491
Cdd:pfam12128 678 dsaNERLNSLEAQLKQ-------LDKKHQAWLEEQKEQKREARTEKQAYWQVVEG--ALDAQLALLKAAIAARRSGAK-- 746
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 492 KEKKTFNQDDSADLRCQ-------LQFAKEEAFLMRKKMAKLGREKDELE----------QELQKYKSLYGDVDSPLPtg 554
Cdd:pfam12128 747 AELKALETWYKRDLASLgvdpdviAKLKREIRTLERKIERIAVRRQEVLRyfdwyqetwlQRRPRLATQLSNIERAIS-- 824
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2217316421 555 EAGGPPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEME 600
Cdd:pfam12128 825 ELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMS 870
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
31-156 |
2.53e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.78 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 31 PVAERRRLHRaPSPARPFLKDLHARPAAPGPAVPSSGrapapaaprspnlAGKAPPSPGSLAAPGRLSRRSGGVPGAKDK 110
Cdd:PRK14951 374 APAEKKTPAR-PEAAAPAAAPVAQAAAAPAPAAAPAA-------------AASAPAAPPAAAPPAPVAAPAAAAPAAAPA 439
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2217316421 111 PPPGAGARAAGGAKAALGSRRA--ARVAPAEPLSRAGKPPGAEPPSAA 156
Cdd:PRK14951 440 AAPAAVALAPAPPAQAAPETVAipVRVAPEPAVASAAPAPAAAPAAAR 487
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
12-185 |
2.59e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.94 E-value: 2.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 12 APDAKLQPPGQHHRHHHLHPV--AERRRLHRAPSPARPFLKDL----HARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAP 85
Cdd:PRK12323 391 APAAAAPAPAAPPAAPAAAPAaaAAARAVAAAPARRSPAPEALaaarQASARGPGGAPAPAPAPAAAPAAAARPAAAGPR 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 86 PSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRagkPPGAEPPSAAAKGRKAKRG 165
Cdd:PRK12323 471 PVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPD---PATADPDDAFETLAPAPAA 547
|
170 180
....*....|....*....|
gi 2217316421 166 SRAPPARTVGPPTPAARIPA 185
Cdd:PRK12323 548 APAPRAAAATEPVVAPRPPR 567
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
7-311 |
3.63e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.62 E-value: 3.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 7 PAGGGAPD------AKLQPPGQHHRHHHLHPVAERRRLHRAPsparpflkdLHARPAAPGPAVPSSGRAPAPAAPRSPNL 80
Cdd:PHA03247 206 PSGPGPAApadltaAALHLYGASETYLQDEPFVERRVVISHP---------LRGDIAAPAPPPVVGEGADRAPETARGAT 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 81 AGKAPPSPGSLAAPGRLSRRS-----GGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKP-------- 147
Cdd:PHA03247 277 GPPPPPEAAAPNGAAAPPDGVwgaalAGAPLALPAPPDPPPPAPAGDAEEEDDEDGAMEVVSPLPRPRQHYPlgfpkrrr 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 148 PGAEPPSAA---AKGRKAKRgsRAPPARTVGPPTPAARIPavtlavtsVAGSPArcsrishtdssSDLSDCPSEPlsdeq 224
Cdd:PHA03247 357 PTWTPPSSLedlSAGRHHPK--RASLPTRKRRSARHAATP--------FARGPG-----------GDDQTRPAAP----- 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 225 rlLPAASSDAESGTGSSDREPPRGAPTPSP-AARGAPPGSPeppallaaplAAGACPGGRSIPSGVSGGFAGPGVAEDVR 303
Cdd:PHA03247 411 --VPASVPTPAPTPVPASAPPPPATPLPSAePGSDDGPAPP----------PERQPPAPATEPAPDDPDDATRKALDALR 478
|
....*...
gi 2217316421 304 GRSPPERP 311
Cdd:PHA03247 479 ERRPPEPP 486
|
|
| EzrA |
COG4477 |
Septation ring formation regulator EzrA [Cell cycle control, cell division, chromosome ... |
350-541 |
3.88e-03 |
|
Septation ring formation regulator EzrA [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443574 [Multi-domain] Cd Length: 567 Bit Score: 42.14 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMR-DSY------LEEdvyQLQELRRELDRANKNcrILQYRLRKAEQKsLKVAETgQVDgELIRSLE 422
Cdd:COG4477 227 LPDQLEELKSGYREMKeQGYvlehlnIEK---EIEQLEEQLKEALEL--LEELDLDEAEEE-LEEIEE-EID-ELYDLLE 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 423 QDLKVAKDVsvrlHHELKTVEEKRAKAEDENETLRqqmIEVEISKQALQ---NELERLKE-----SSLKRR---STREMY 491
Cdd:COG4477 299 KEVEAKKYV----DKNQEELEEYLEHLKEQNRELK---EEIDRVQQSYRlneNELEKVRNlekqiEELEKRydeIDERIE 371
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2217316421 492 KEKKTFN--QDDSADLRCQLQFAKEEAFLMRKKMAKLgrEKDELE--QELQKYK 541
Cdd:COG4477 372 EEKVAYSelQEELEEIEEQLEEIEEEQEEFSEKLKSL--RKDELEarEKLDELK 423
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
36-184 |
4.07e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 42.36 E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 36 RRLHRAPSPARPflkdlhaRPAAPGPAVPSSGRAPAPAAPrspnlAGKAPPSPGSLAAPGRLsRRSGGVPGAKdkPPPGA 115
Cdd:PHA03378 685 LPIQWAPGTMQP-------PPRAPTPMRPPAAPPGRAQRP-----AAATGRARPPAAAPGRA-RPPAAAPGRA--RPPAA 749
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217316421 116 GARAAGGAKAALGSRRAARVAPaeplsraGKPPGAEPPSAAAKGRKAKRGSRAPPARTVGPPTPAARIP 184
Cdd:PHA03378 750 APGRARPPAAAPGRARPPAAAP-------GAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMP 811
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
355-561 |
4.77e-03 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 41.92 E-value: 4.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 355 DELRAEMEEMRDSYLEEdvyQLQELRRELDRA---------NKNCRILQ---YRLRKAEQKSlKVAETGQVDGELIRSLE 422
Cdd:NF033838 53 NESQKEHAKEVESHLEK---ILSEIQKSLDKRkhtqnvalnKKLSDIKTeylYELNVLKEKS-EAELTSKTKKELDAAFE 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 423 QDLKVAKDVSVRLHHELKTVEEKRAKAEDENE-------TLRQQMIEVEISKQALQnelerLKESSLkrrstrEMYKEKK 495
Cdd:NF033838 129 QFKKDTLEPGKKVAEATKKVEEAEKKAKDQKEedrrnypTNTYKTLELEIAESDVE-----VKKAEL------ELVKEEA 197
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217316421 496 TFNQDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPS 561
Cdd:NF033838 198 KEPRDEEKIKQAKAKVESKKAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKR 263
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
350-516 |
5.02e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 5.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQdLKVAK 429
Cdd:COG3883 35 AQAELDALQAELEELNEEYNELQA-ELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDV-LLGSE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 430 DVS-------------------VRLHHELK-TVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTRE 489
Cdd:COG3883 113 SFSdfldrlsalskiadadadlLEELKADKaELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEA 192
|
170 180
....*....|....*....|....*..
gi 2217316421 490 MYKEKKTFNQDDSADLRCQLQFAKEEA 516
Cdd:COG3883 193 AAEAQLAELEAELAAAEAAAAAAAAAA 219
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
350-542 |
6.30e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 41.38 E-value: 6.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYLE-EDVY--QLQELR---RELDRANkncrilqYRLrkaeqKSLKVAET-GQVDGELIRSLE 422
Cdd:pfam06160 184 LEEETDALEELMEDIPPLYEElKTELpdQLEELKegyREMEEEG-------YAL-----EHLNVDKEiQQLEEQLEENLA 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 423 Q----DLKVAKDVSVRLHHELKTV-----EEKRAKAE-DEN-ETLRQQMIEVEISKQALQNELERLKES----------- 480
Cdd:pfam06160 252 LlenlELDEAEEALEEIEERIDQLydlleKEVDAKKYvEKNlPEIEDYLEHAEEQNKELKEELERVQQSytlnenelerv 331
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217316421 481 --------SLKRR---STREMYKEKKTFN--QDDSADLRCQLQFAKEEAFLMRKKMAKLgrEKDELE--QELQKYKS 542
Cdd:pfam06160 332 rglekqleELEKRydeIVERLEEKEVAYSelQEELEEILEQLEEIEEEQEEFKESLQSL--RKDELEarEKLDEFKL 406
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
350-543 |
7.86e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.20 E-value: 7.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEMRDSYLEEDVYQLQELRR------ELDRANKNCRILQYRLRKAEQKslkvaetgqvdgelirsLEQ 423
Cdd:PRK03918 568 LEEELAELLKELEELGFESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEEE-----------------LDK 630
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 424 DLKVAKDVSVRLHHELKTVEEKRAK-AEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTfnqdds 502
Cdd:PRK03918 631 AFEELAETEKRLEELRKELEELEKKySEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE------ 704
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2217316421 503 adlrcQLQFAKEEAFLMRKKMAKLgrekDELEQELQKYKSL 543
Cdd:PRK03918 705 -----EREKAKKELEKLEKALERV----EELREKVKKYKAL 736
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
56-329 |
7.97e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 41.10 E-value: 7.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 56 PAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRS---------GGVP---GAKDKPPPGAGARAAGGA 123
Cdd:pfam17823 115 LAAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAaiaaasaphAASPaprTAASSTTAASSTTAASSA 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 124 KAALGSRRAARVAPAEPLSRAGKPPGAepPSAAAKgrKAKRGSRAPPART----VGPPTPA--ARIPAVTLAVTSVAGSP 197
Cdd:pfam17823 195 PTTAASSAPATLTPARGISTAATATGH--PAAGTA--LAAVGNSSPAAGTvtaaVGTVTPAalATLAAAAGTVASAAGTI 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 198 ARCSRISHTDSSSdlSDCPSEPLSDEqrllPAASSDAES-GTGS--SDREP---PRGAPTPSPAARGAPPGSPEPPALLA 271
Cdd:pfam17823 271 NMGDPHARRLSPA--KHMPSDTMARN----PAAPMGAQAqGPIIqvSTDQPvhnTAGEPTPSPSNTTLEPNTPKSVASTN 344
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217316421 272 APLAAGACPGGRSiPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVP 329
Cdd:pfam17823 345 LAVVTTTKAQAKE-PSASPVPVLHTSMIPEVEATSPTTQPSPLLPTQGAAGPGILLAP 401
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
438-711 |
8.21e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.03 E-value: 8.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 438 ELKTVEEKRAKAEDENETL----RQQMIEVEISK-QALQNELERLKESSLKRRST-REMYKEKKTFNQDDSADLRCQLQF 511
Cdd:pfam07888 5 ELVTLEEESHGEEGGTDMLlvvpRAELLQNRLEEcLQERAELLQAQEAANRQREKeKERYKRDREQWERQRRELESRVAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 512 AKEEaflmrkkmakLGREKDELEQELQKYKSLygdVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIVELEVE 591
Cdd:pfam07888 85 LKEE----------LRQSREKHEELEEKYKEL---SASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETE 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 592 NRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLESSTE---LRRHLQFVEEEAELLRRSISEIED-----HNRQLT 663
Cdd:pfam07888 152 LERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEfqeLRNSLAQRDTQVLQLQDTITTLTQklttaHRKEAE 231
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2217316421 664 HELSKFKFEPPRE--------PGWLGEGASPGAGGGAPLQEELKSARLQISELSGK 711
Cdd:pfam07888 232 NEALLEELRSLQErlnaserkVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQ 287
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
350-538 |
8.32e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.21 E-value: 8.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 350 LKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDRANKNCR-ILQYRLRKAEQKSLKVAETGQVDGELIRSLEQ----- 423
Cdd:TIGR02169 327 LEAEIDKLLAEIEE-----LEREIEEERKRRDKLTEEYAELKeELEDLRAELEEVDKEFAETRDELKDYREKLEKlkrei 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 424 -DLKVAKDvsvRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERlKESSLKRrstremykekktfNQDDS 502
Cdd:TIGR02169 402 nELKRELD---RLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK-QEWKLEQ-------------LAADL 464
|
170 180 190
....*....|....*....|....*....|....*.
gi 2217316421 503 ADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQ 538
Cdd:TIGR02169 465 SKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500
|
|
| Tropomyosin |
pfam00261 |
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ... |
418-539 |
8.43e-03 |
|
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.
Pssm-ID: 459736 [Multi-domain] Cd Length: 235 Bit Score: 40.01 E-value: 8.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 418 IRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETL--RQQMIEVEI--SKQALQNELERLKESSLKRRSTREMYK- 492
Cdd:pfam00261 3 MQQIKEELDEAEERLKEAMKKLEEAEKRAEKAEAEVAALnrRIQLLEEELerTEERLAEALEKLEEAEKAADESERGRKv 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2217316421 493 -EKKTFNQDDS-ADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQK 539
Cdd:pfam00261 83 lENRALKDEEKmEILEAQLKEAKEIAEEADRKYEEVARKLVVVEGDLER 131
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
369-603 |
8.54e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 40.67 E-value: 8.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 369 LEEDVYQLQELRRELDRAnKNCRILQYRLrkAEQKSLKVAETgqvdgelirslEQDLKVAKDVSVRLHHELKTVEEKRAK 448
Cdd:pfam13868 1 LRENSDELRELNSKLLAA-KCNKERDAQI--AEKKRIKAEEK-----------EEERRLDEMMEEERERALEEEEEKEEE 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 449 AEDENETLRQqmievEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSAD----------LRCQLQFAKEEAFL 518
Cdd:pfam13868 67 RKEERKRYRQ-----ELEEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEaeeklekqrqLREEIDEFNEEQAE 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 519 MRKKMAKLGREKDELEQELQKYKSLygdvdsplptgeaggppstREAELKLRLKLVEEEANILGRKIVELEVENRGLKAE 598
Cdd:pfam13868 142 WKELEKEEEREEDERILEYLKEKAE-------------------REEEREAEREEIEEEKEREIARLRAQQEKAQDEKAE 202
|
....*
gi 2217316421 599 MEDMR 603
Cdd:pfam13868 203 RDELR 207
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
443-662 |
9.39e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.05 E-value: 9.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 443 EEKRAKAEDENETLRQQMIEVEISKQALQNELERLKEsslkRRSTREMYKEKkTFNQDDSADLRcqlqfakeeaflmrkk 522
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQE----RREALQRLAEY-SWDEIDVASAE---------------- 667
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 523 maklgREKDELEQELQKYKSLYGDVdsplptgeaggppstreAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDM 602
Cdd:COG4913 668 -----REIAELEAELERLDASSDDL-----------------AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA 725
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217316421 603 RGQQEREGPGRDHAPSIPTSPFGDSLEsstELRRHLQFVEEEAELLRRSISEIEDHNRQL 662
Cdd:COG4913 726 EEELDELQDRLEAAEDLARLELRALLE---ERFAAALGDAVERELRENLEERIDALRARL 782
|
|
| |
