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Conserved domains on  [gi|2217341969|ref|XP_047303441|]
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tetratricopeptide repeat protein 14 isoform X4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 260-380 3.11e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.37  E-value: 3.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 260 KIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGgq 339
Cdd:COG4783     9 ALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG-- 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2217341969 340 leeeeKFLNAESYYKKALALDETFKDAEDALQKLHKYMQRK 380
Cdd:COG4783    87 -----DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRP 122
S1 smart00316
Ribosomal protein S1-like RNA-binding domain;
124-207 2.24e-06

Ribosomal protein S1-like RNA-binding domain;


:

Pssm-ID: 197648 [Multi-domain]  Cd Length: 72  Bit Score: 44.90  E-value: 2.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969  124 ERGDIVIGRISSIREFGFFmVLICLGsgimrdiahleITALCPLRDVpSHSNHGDPLSYYQTGDIIRAGIKDIDRYHEKL 203
Cdd:smart00316   1 EVGDVVEGTVTEITPGGAF-VDLGNG-----------VEGLIPISEL-SDKRVKDPEEVLKVGDEVKVKVLSVDEEKGRI 67


                   ....
gi 2217341969  204 AVSL 207
Cdd:smart00316  68 ILSL 71
 
Name Accession Description Interval E-value
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 260-380 3.11e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.37  E-value: 3.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 260 KIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGgq 339
Cdd:COG4783     9 ALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG-- 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2217341969 340 leeeeKFLNAESYYKKALALDETFKDAEDALQKLHKYMQRK 380
Cdd:COG4783    87 -----DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRP 122
S1 smart00316
Ribosomal protein S1-like RNA-binding domain;
124-207 2.24e-06

Ribosomal protein S1-like RNA-binding domain;


Pssm-ID: 197648 [Multi-domain]  Cd Length: 72  Bit Score: 44.90  E-value: 2.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969  124 ERGDIVIGRISSIREFGFFmVLICLGsgimrdiahleITALCPLRDVpSHSNHGDPLSYYQTGDIIRAGIKDIDRYHEKL 203
Cdd:smart00316   1 EVGDVVEGTVTEITPGGAF-VDLGNG-----------VEGLIPISEL-SDKRVKDPEEVLKVGDEVKVKVLSVDEEKGRI 67


                   ....
gi 2217341969  204 AVSL 207
Cdd:smart00316  68 ILSL 71
TPR_11 pfam13414
TPR repeat;
265-303 2.84e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 40.92  E-value: 2.84e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2217341969 265 YFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKG 303
Cdd:pfam13414   4 YYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 278-359 5.97e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.54  E-value: 5.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 278 YNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHrNARKYLCqtLvergGQLEEEEkflNAESYYKKAL 357
Cdd:cd24142    23 LQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG-GYEKYLY--L----GQLSGGE---EALQYYEKGI 92


                  ..
gi 2217341969 358 AL 359
Cdd:cd24142    93 EI 94
PRK00087 PRK00087
bifunctional 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/30S ribosomal protein S1;
115-207 2.11e-04

bifunctional 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/30S ribosomal protein S1;


Pssm-ID: 234623 [Multi-domain]  Cd Length: 647  Bit Score: 43.40  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 115 RRELFFRDIERGDIVIGRISSIREFGFFMvliclgsgimrDIAHLEitALCPLRDVpSHSNHGDPLSYYQTGDIIRAGIK 194
Cdd:PRK00087  467 KKEETWNSLEEGDVVEGEVKRLTDFGAFV-----------DIGGVD--GLLHVSEI-SWGRVEKPSDVLKVGDEIKVYIL 532

                          90
                  ....*....|...
gi 2217341969 195 DIDRYHEKLAVSL 207
Cdd:PRK00087  533 DIDKENKKLSLSL 545
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 238-373 3.21e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 3.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 238 SEDDFASALRKKQSASWAlkcvKIGVDYFKV--GRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELA 315
Cdd:TIGR02917 144 AQKSYEQALAIDPRSLYA----KLGLAQLALaeNRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKA 219

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217341969 316 LENCPTHRNARKYLCQTLVERgGQLEEEEKFLNA---------ESYYKKALaLDETFKDAEDALQKL 373
Cdd:TIGR02917 220 IALRPNNIAVLLALATILIEA-GEFEEAEKHADAllkkapnspLAHYLKAL-VDFQKKNYEDARETL 284
RpsA COG0539
Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S1 ...
 115-207 7.09e-04

Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S1 is part of the Pathway/BioSystem: Ribosome 30S subunit


Pssm-ID: 440305 [Multi-domain]  Cd Length: 348  Bit Score: 41.18  E-value: 7.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 115 RRELFFRDIERGDIVIGRISSIREFGFFmvlICLGsGI-----MRDIAHleitalcplrdvpSHSNHgdPLSYYQTGDII 189
Cdd:COG0539   179 KREELLEKLEEGDVVEGTVKNITDFGAF---VDLG-GVdgllhISEISW-------------GRVKH--PSEVLKVGDEV 239

                          90
                  ....*....|....*...
gi 2217341969 190 RAGIKDIDRYHEKLAVSL 207
Cdd:COG0539   240 EVKVLKIDREKERISLSL 257
S1_like cd00164
S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of ...
 129-206 1.88e-03

S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. Both domains are members of the Oligonucleotide/oligosaccharide Binding (OB) fold.


Pssm-ID: 238094 [Multi-domain]  Cd Length: 65  Bit Score: 36.59  E-value: 1.88e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217341969 129 VIGRISSIREFGFFmvlICLGSGImrdiahleiTALCPLRDVpSHSNHGDPLSYYQTGDIIRAGIKDIDRYHEKLAVS 206
Cdd:cd00164     1 VTGKVVSITKFGVF---VELEDGV---------EGLVHISEL-SDKFVKDPSEVFKVGDEVEVKVLEVDPEKGRISLS 65
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 237-362 2.38e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 40.07  E-value: 2.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969  237 FSEDDFASALRK------KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIE 310
Cdd:PRK11447   245 FSDGDSVAAARSqlaeqqKQLADPAFRARAQGLAAVDSGQGGKAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVA 324

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217341969  311 DFELALENCPTHRNARKY--LCQT-----LVERGGQLEEEEKFLNAESYYKKALALDET 362
Cdd:PRK11447   325 QFEKALALDPHSSNRDKWesLLKVnrywlLIQQGDAALKANNLAQAERLYQQARQVDNT 383
S1 pfam00575
S1 RNA binding domain; The S1 domain occurs in a wide range of RNA associated proteins. It is ...
 124-207 4.85e-03

S1 RNA binding domain; The S1 domain occurs in a wide range of RNA associated proteins. It is structurally similar to cold shock protein which binds nucleic acids. The S1 domain has an OB-fold structure.


Pssm-ID: 425760 [Multi-domain]  Cd Length: 72  Bit Score: 35.34  E-value: 4.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 124 ERGDIVIGRISSIREFGFFmvlICLGSGimrdiahleITALCPLRDVPSHSnHGDPLSYYQTGDIIRAGIKDIDRYHEKL 203
Cdd:pfam00575   2 EKGDVVEGEVTRVTKGGAF---VDLGNG---------VEGFIPISELSDDH-VEDPDEVIKVGDEVKVKVLKVDKDRRRI 68


                  ....
gi 2217341969 204 AVSL 207
Cdd:pfam00575  69 ILSI 72
 
Name Accession Description Interval E-value
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 260-380 3.11e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.37  E-value: 3.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 260 KIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGgq 339
Cdd:COG4783     9 ALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG-- 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2217341969 340 leeeeKFLNAESYYKKALALDETFKDAEDALQKLHKYMQRK 380
Cdd:COG4783    87 -----DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRP 122
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
261-379 3.94e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.41  E-value: 3.94e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 261 IGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGgQL 340
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALG-RY 92

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2217341969 341 EEeekflnAESYYKKALALDETFKDAEDALQKLHKYMQR 379
Cdd:COG0457    93 EE------ALEDYDKALELDPDDAEALYNLGLALLELGR 125
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 265-360 2.03e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.79  E-value: 2.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 265 YFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLcqtlverGGQLEEEE 344
Cdd:COG4235    27 YLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLL-------GLAAFQQG 99

                          90
                  ....*....|....*.
gi 2217341969 345 KFLNAESYYKKALALD 360
Cdd:COG4235   100 DYAEAIAAWQKLLALL 115
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 261-366 2.63e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.01  E-value: 2.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 261 IGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLvERGGQL 340
Cdd:COG3914   118 LGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNAL-QDLGRL 196

                          90       100
                  ....*....|....*....|....*.
gi 2217341969 341 EEeekflnAESYYKKALALDETFKDA 366
Cdd:COG3914   197 EE------AIAAYRRALELDPDNADA 216
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 242-380 3.04e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.21  E-value: 3.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 242 FASALRKKQSASWALkcVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPT 321
Cdd:COG2956    65 HQKLLERDPDRAEAL--LELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPE 142

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217341969 322 HRNArkylcqtLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLhkYMQRK 380
Cdd:COG2956   143 NAHA-------YCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAEL--YLEQG 192
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
239-376 3.92e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 3.92e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 239 EDDFASALRKKQSASWALkcVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALEN 318
Cdd:COG0457    62 LADYEQALELDPDDAEAL--NNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL 139

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217341969 319 CPTHRNARKYLCQTLVERgGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKY 376
Cdd:COG0457   140 DPDDADALYNLGIALEKL-GRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVL 196
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
265-360 1.86e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.10  E-value: 1.86e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 265 YFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEdFELALENCPTHRNARKYLCQTLVERGgqleeee 344
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELG------- 73

                          90
                  ....*....|....*.
gi 2217341969 345 KFLNAESYYKKALALD 360
Cdd:COG3063    74 DYDEALAYLERALELD 89
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 265-360 3.26e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.05  E-value: 3.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 265 YFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGgqleeee 344
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLG------- 136

                          90
                  ....*....|....*.
gi 2217341969 345 KFLNAESYYKKALALD 360
Cdd:COG5010   137 QDDEAKAALQRALGTS 152
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 262-380 6.18e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.36  E-value: 6.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 262 GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERgGQLE 341
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA-GLLD 93

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2217341969 342 EeekflnAESYYKKALALDEtfkDAEDALQKL-HKYMQRK 380
Cdd:COG2956    94 R------AEELLEKLLELDP---DDAEALRLLaEIYEQEG 124
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 239-360 6.79e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.74  E-value: 6.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 239 EDDFASALRKKQSASWALkcVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALEN 318
Cdd:COG4783    24 EALLEKALELDPDNPEAF--ALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKL 101

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2217341969 319 CPTHRNARKYLCQTLVERGgqleeeeKFLNAESYYKKALALD 360
Cdd:COG4783   102 DPEHPEAYLRLARAYRALG-------RPDEAIAALEKALELD 136
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 269-366 3.27e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 3.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 269 GRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERgGQLEEeekfln 348
Cdd:COG3914    92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL-GRLEE------ 164

                          90
                  ....*....|....*...
gi 2217341969 349 AESYYKKALALDETFKDA 366
Cdd:COG3914   165 AIAALRRALELDPDNAEA 182
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
191-370 6.23e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 55.69  E-value: 6.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 191 AGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYSKNFSEDDFASALRKKQSASWALKCVKI----GVDYF 266
Cdd:COG4785     5 ALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLyyerGVAYD 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 267 KVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLvERGGQLEEeekf 346
Cdd:COG4785    85 SLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIAL-YYLGRYEL---- 159

                         170       180
                  ....*....|....*....|....
gi 2217341969 347 lnAESYYKKALALDEtfKDAEDAL 370
Cdd:COG4785   160 --AIADLEKALELDP--NDPERAL 179
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 241-380 2.63e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 2.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 241 DFASALRKKQSASWALKCvKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCP 320
Cdd:COG2956   131 EVLERLLKLGPENAHAYC-ELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDP 209

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217341969 321 THRNARKYLCQTLVERgGQLEEeekflnAESYYKKALALD-------------ETFKDAEDALQKLHKYMQRK 380
Cdd:COG2956   210 DYLPALPRLAELYEKL-GDPEE------ALELLRKALELDpsddlllaladllERKEGLEAALALLERQLRRH 275
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
262-358 1.53e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.84  E-value: 1.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 262 GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTH--RNARKYLCQTLV----- 334
Cdd:COG4785   114 GLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDpeRALWLYLAERKLdpeka 193

                          90       100       110
                  ....*....|....*....|....*....|
gi 2217341969 335 ------ERGGQLEEEEKFLNAESYYKKALA 358
Cdd:COG4785   194 lallleDWATAYLLQGDTEEARELFKLALA 223
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 239-379 4.30e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.92  E-value: 4.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 239 EDDFASALRKKqsASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALEN 318
Cdd:COG3914   132 LAALRRALALN--PDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALEL 209

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217341969 319 CPTHRNARKYLCQTLVERGGqLEEEEKFLNAESYYKKALALDETFK-------DAEDALQKLHKYMQR 379
Cdd:COG3914   210 DPDNADAHSNLLFALRQACD-WEVYDRFEELLAALARGPSELSPFAllylpddDPAELLALARAWAQL 276
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
239-380 8.94e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.62  E-value: 8.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 239 EDDFASALRKKQSASWALkcVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALEN 318
Cdd:COG0457    96 LEDYDKALELDPDDAEAL--YNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217341969 319 cptHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQRK 380
Cdd:COG0457   174 ---ALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLA 232
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
282-376 1.33e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.23  E-value: 1.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 282 LEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERgGQLEEeekflnAESYYKKALALDE 361
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRL-GRYEE------ALADYEQALELDP 73

                          90
                  ....*....|....*....
gi 2217341969 362 TFKDA----EDALQKLHKY 376
Cdd:COG0457    74 DDAEAlnnlGLALQALGRY 92
S1 smart00316
Ribosomal protein S1-like RNA-binding domain;
124-207 2.24e-06

Ribosomal protein S1-like RNA-binding domain;


Pssm-ID: 197648 [Multi-domain]  Cd Length: 72  Bit Score: 44.90  E-value: 2.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969  124 ERGDIVIGRISSIREFGFFmVLICLGsgimrdiahleITALCPLRDVpSHSNHGDPLSYYQTGDIIRAGIKDIDRYHEKL 203
Cdd:smart00316   1 EVGDVVEGTVTEITPGGAF-VDLGNG-----------VEGLIPISEL-SDKRVKDPEEVLKVGDEVKVKVLSVDEEKGRI 67


                   ....
gi 2217341969  204 AVSL 207
Cdd:smart00316  68 ILSL 71
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 273-366 1.53e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 1.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 273 DAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGGQLEeeekflnAESY 352
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEE-------AEEL 73

                          90
                  ....*....|....
gi 2217341969 353 YKKALALDETFKDA 366
Cdd:COG4235    74 LERALALDPDNPEA 87
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
239-320 1.73e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.85  E-value: 1.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 239 EDDFASALRKKQSASWALkcVKIGVDYFKVGRHVDAMnEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALEN 318
Cdd:COG3063    12 EEYYEKALELDPDNADAL--NNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88


                  ..
gi 2217341969 319 CP 320
Cdd:COG3063    89 DP 90
TPR_11 pfam13414
TPR repeat;
265-303 2.84e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 40.92  E-value: 2.84e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2217341969 265 YFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKG 303
Cdd:pfam13414   4 YYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 231-322 4.26e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.87  E-value: 4.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 231 LYYSKNFSE--DDFASALRKKQSASWALkcVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA 308
Cdd:COG4783    48 LLQLGDLDEaiVLLHEALELDPDEPEAR--LNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEA 125

                          90
                  ....*....|....
gi 2217341969 309 IEDFELALENCPTH 322
Cdd:COG4783   126 IAALEKALELDPDD 139
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 278-359 5.97e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.54  E-value: 5.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 278 YNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHrNARKYLCqtLvergGQLEEEEkflNAESYYKKAL 357
Cdd:cd24142    23 LQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG-GYEKYLY--L----GQLSGGE---EALQYYEKGI 92


                  ..
gi 2217341969 358 AL 359
Cdd:cd24142    93 EI 94
PRK00087 PRK00087
bifunctional 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/30S ribosomal protein S1;
115-207 2.11e-04

bifunctional 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/30S ribosomal protein S1;


Pssm-ID: 234623 [Multi-domain]  Cd Length: 647  Bit Score: 43.40  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 115 RRELFFRDIERGDIVIGRISSIREFGFFMvliclgsgimrDIAHLEitALCPLRDVpSHSNHGDPLSYYQTGDIIRAGIK 194
Cdd:PRK00087  467 KKEETWNSLEEGDVVEGEVKRLTDFGAFV-----------DIGGVD--GLLHVSEI-SWGRVEKPSDVLKVGDEIKVYIL 532

                          90
                  ....*....|...
gi 2217341969 195 DIDRYHEKLAVSL 207
Cdd:PRK00087  533 DIDKENKKLSLSL 545
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 238-373 3.21e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 3.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 238 SEDDFASALRKKQSASWAlkcvKIGVDYFKV--GRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELA 315
Cdd:TIGR02917 144 AQKSYEQALAIDPRSLYA----KLGLAQLALaeNRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKA 219

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217341969 316 LENCPTHRNARKYLCQTLVERgGQLEEEEKFLNA---------ESYYKKALaLDETFKDAEDALQKL 373
Cdd:TIGR02917 220 IALRPNNIAVLLALATILIEA-GEFEEAEKHADAllkkapnspLAHYLKAL-VDFQKKNYEDARETL 284
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
287-379 4.00e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.44  E-value: 4.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 287 QNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYlcqtlveRGGQLEEEEKFLNAESYYKKALALDETFKDA 366
Cdd:COG4785    71 DLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNN-------RGLAYLLLGDYDAALEDFDRALELDPDYAYA 143

                          90
                  ....*....|...
gi 2217341969 367 EDALQKLHKYMQR 379
Cdd:COG4785   144 YLNRGIALYYLGR 156
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 277-380 4.82e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.33  E-value: 4.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 277 EYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERgGQLEEeekflnAESYYKKA 356
Cdd:COG5010    42 LAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRS-GDKDE------AKEYYEKA 114

                          90       100
                  ....*....|....*....|....
gi 2217341969 357 LALDETFKDAEDALQKLHKYMQRK 380
Cdd:COG5010   115 LALSPDNPNAYSNLAALLLSLGQD 138
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 261-320 5.60e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.33  E-value: 5.60e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 261 IGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCP 320
Cdd:COG5010    94 LALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
RpsA COG0539
Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S1 ...
 115-207 7.09e-04

Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S1 is part of the Pathway/BioSystem: Ribosome 30S subunit


Pssm-ID: 440305 [Multi-domain]  Cd Length: 348  Bit Score: 41.18  E-value: 7.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 115 RRELFFRDIERGDIVIGRISSIREFGFFmvlICLGsGI-----MRDIAHleitalcplrdvpSHSNHgdPLSYYQTGDII 189
Cdd:COG0539   179 KREELLEKLEEGDVVEGTVKNITDFGAF---VDLG-GVdgllhISEISW-------------GRVKH--PSEVLKVGDEV 239

                          90
                  ....*....|....*...
gi 2217341969 190 RAGIKDIDRYHEKLAVSL 207
Cdd:COG0539   240 EVKVLKIDREKERISLSL 257
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 287-370 8.69e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.40  E-value: 8.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 287 QNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERgGQLEEeekflnAESYYKKALALDETFKDA 366
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQL-GDLDE------AIVLLHEALELDPDEPEA 74


                  ....
gi 2217341969 367 EDAL 370
Cdd:COG4783    75 RLNL 78
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 243-379 1.57e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 1.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 243 ASALRKKQSASWALKcvkiGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTH 322
Cdd:TIGR02917 593 AADAAPDSPEAWLML----GRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDN 668

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217341969 323 RNARKYLCQTLVErGGQLEEEEKFLNA-ESYYKKALALDE-------TFKDAEDALQKLHKYMQR 379
Cdd:TIGR02917 669 TEAQIGLAQLLLA-AKRTESAKKIAKSlQKQHPKAALGFElegdlylRQKDYPAAIQAYRKALKR 732
S1_like cd00164
S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of ...
 129-206 1.88e-03

S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. Both domains are members of the Oligonucleotide/oligosaccharide Binding (OB) fold.


Pssm-ID: 238094 [Multi-domain]  Cd Length: 65  Bit Score: 36.59  E-value: 1.88e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217341969 129 VIGRISSIREFGFFmvlICLGSGImrdiahleiTALCPLRDVpSHSNHGDPLSYYQTGDIIRAGIKDIDRYHEKLAVS 206
Cdd:cd00164     1 VTGKVVSITKFGVF---VELEDGV---------EGLVHISEL-SDKFVKDPSEVFKVGDEVEVKVLEVDPEKGRISLS 65
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 231-327 2.02e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 2.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 231 LYYSKNFSE--DDFASALRKKQSASWALKC-VKIGVDYFKVGRHVDAMNEYNKALEIDKQNV---EALVARGALYATKGS 304
Cdd:COG1729     3 LLKAGDYDEaiAAFKAFLKRYPNSPLAPDAlYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkapDALLKLGLSYLELGD 82

                          90       100
                  ....*....|....*....|...
gi 2217341969 305 LNKAIEDFELALENCPTHRNARK 327
Cdd:COG1729    83 YDKARATLEELIKKYPDSEAAKE 105
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 237-362 2.38e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 40.07  E-value: 2.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969  237 FSEDDFASALRK------KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIE 310
Cdd:PRK11447   245 FSDGDSVAAARSqlaeqqKQLADPAFRARAQGLAAVDSGQGGKAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVA 324

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217341969  311 DFELALENCPTHRNARKY--LCQT-----LVERGGQLEEEEKFLNAESYYKKALALDET 362
Cdd:PRK11447   325 QFEKALALDPHSSNRDKWesLLKVnrywlLIQQGDAALKANNLAQAERLYQQARQVDNT 383
TPR_1 pfam00515
Tetratricopeptide repeat;
289-322 4.19e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 4.19e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2217341969 289 VEALVARGALYATKGSLNKAIEDFELALENCPTH 322
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 285-359 4.49e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 4.49e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217341969 285 DKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGgqleeeeKFLNAESYYKKALAL 359
Cdd:TIGR02917  18 GDQSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALG-------DYAAAEKELRKALSL 85
S1 pfam00575
S1 RNA binding domain; The S1 domain occurs in a wide range of RNA associated proteins. It is ...
 124-207 4.85e-03

S1 RNA binding domain; The S1 domain occurs in a wide range of RNA associated proteins. It is structurally similar to cold shock protein which binds nucleic acids. The S1 domain has an OB-fold structure.


Pssm-ID: 425760 [Multi-domain]  Cd Length: 72  Bit Score: 35.34  E-value: 4.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217341969 124 ERGDIVIGRISSIREFGFFmvlICLGSGimrdiahleITALCPLRDVPSHSnHGDPLSYYQTGDIIRAGIKDIDRYHEKL 203
Cdd:pfam00575   2 EKGDVVEGEVTRVTKGGAF---VDLGNG---------VEGFIPISELSDDH-VEDPDEVIKVGDEVKVKVLKVDKDRRRI 68


                  ....
gi 2217341969 204 AVSL 207
Cdd:pfam00575  69 ILSI 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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