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Conserved domains on  [gi|2296769121|ref|XP_050462989|]
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DDB1- and CUL4-associated factor 7 [Cataglyphis hispanica]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 1000017)

WD40 repeat domain-containing protein folds into a beta-propeller structure and functions as a scaffold, providing a platform for the interaction and assembly of several proteins into a signalosome; similar to a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
Gene Ontology:  GO:0005515
PubMed:  10322433|8090199|30069656|29026209
SCOP:  4002744

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
WD40 super family cl29593
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 21-298 4.71e-17

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


The actual alignment was detected with superfamily member cd00200:

Pssm-ID: 475233 [Multi-domain]  Cd Length: 289  Bit Score: 80.07  E-value: 4.71e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  21 PLYSMNWSvrPDKRFrLALGSfveeYNNKVQIVSLDEETSEFSAKStfdHPYPTTKIMWIPDSKglfpdLLATSGD--YL 98
Cdd:cd00200    11 GVTCVAFS--PDGKL-LATGS----GDGTIKVWDLETGELLRTLKG---HTGPVRDVAASADGT-----YLASGSSdkTI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  99 RVWRAAEPE--TRLECvlnnnknsdFCAPLTSFDWNeVDPNLIGTSSIDTTCTIWGLETGQVL-------GRVNMV---- 165
Cdd:cd00200    76 RLWDLETGEcvRTLTG---------HTSYVSSVAFS-PDGRILSSSSRDKTIKVWDVETGKCLttlrghtDWVNSVafsp 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 166 --------------------TGHVKTQLIAHDKEVYDIAFSraGGGRDMFASvGADGSVRMFDLRHLEHSTIIyedPQHT 225
Cdd:cd00200   146 dgtfvasssqdgtiklwdlrTGKCVATLTGHTGEVNSVAFS--PDGEKLLSS-SSDGTIKLWDLSTGKCLGTL---RGHE 219

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2296769121 226 -PLLRLAWNkQDPNYLATVAMDaCEVIILDVRvPCTPVARLSNHRASVNGIAWAPhSSCHICTAGDDNQALIWD 298
Cdd:cd00200   220 nGVNSVAFS-PDGYLLASGSED-GTIRVWDLR-TGECVQTLSGHTNSVTSLAWSP-DGKRLASGSADGTIRIWD 289
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 21-298 4.71e-17

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 80.07  E-value: 4.71e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  21 PLYSMNWSvrPDKRFrLALGSfveeYNNKVQIVSLDEETSEFSAKStfdHPYPTTKIMWIPDSKglfpdLLATSGD--YL 98
Cdd:cd00200    11 GVTCVAFS--PDGKL-LATGS----GDGTIKVWDLETGELLRTLKG---HTGPVRDVAASADGT-----YLASGSSdkTI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  99 RVWRAAEPE--TRLECvlnnnknsdFCAPLTSFDWNeVDPNLIGTSSIDTTCTIWGLETGQVL-------GRVNMV---- 165
Cdd:cd00200    76 RLWDLETGEcvRTLTG---------HTSYVSSVAFS-PDGRILSSSSRDKTIKVWDVETGKCLttlrghtDWVNSVafsp 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 166 --------------------TGHVKTQLIAHDKEVYDIAFSraGGGRDMFASvGADGSVRMFDLRHLEHSTIIyedPQHT 225
Cdd:cd00200   146 dgtfvasssqdgtiklwdlrTGKCVATLTGHTGEVNSVAFS--PDGEKLLSS-SSDGTIKLWDLSTGKCLGTL---RGHE 219

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2296769121 226 -PLLRLAWNkQDPNYLATVAMDaCEVIILDVRvPCTPVARLSNHRASVNGIAWAPhSSCHICTAGDDNQALIWD 298
Cdd:cd00200   220 nGVNSVAFS-PDGYLLASGSED-GTIRVWDLR-TGECVQTLSGHTNSVTSLAWSP-DGKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
70-300 2.41e-16

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 79.18  E-value: 2.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  70 HPYPTTKIMWIPDSKglfpdLLATSGDY--LRVWRAAEPETRLecVLNNNKNsdfcaPLTSFDWNEvDPNLIGTSSIDTT 147
Cdd:COG2319   161 HSGAVTSVAFSPDGK-----LLASGSDDgtVRLWDLATGKLLR--TLTGHTG-----AVRSVAFSP-DGKLLASGSADGT 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 148 CTIWGLETGQVLGRvnmvtghvktqLIAHDKEVYDIAFSRAGggrDMFASVGADGSVRMFDLRHLEHSTIIyeDPQHTPL 227
Cdd:COG2319   228 VRLWDLATGKLLRT-----------LTGHSGSVRSVAFSPDG---RLLASGSADGTVRLWDLATGELLRTL--TGHSGGV 291

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2296769121 228 LRLAWNKqDPNYLATVAMDAcEVIILDVRVPcTPVARLSNHRASVNGIAWAPHSScHICTAGDDNQALIWDIQ 300
Cdd:COG2319   292 NSVAFSP-DGKLLASGSDDG-TVRLWDLATG-KLLRTLTGHTGAVRSVAFSPDGK-TLASGSDDGTVRLWDLA 360
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 260-298 3.00e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 40.76  E-value: 3.00e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2296769121  260 TPVARLSNHRASVNGIAWAPHSScHICTAGDDNQALIWD 298
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGK-YLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
260-298 6.61e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 36.94  E-value: 6.61e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2296769121 260 TPVARLSNHRASVNGIAWAPHSScHICTAGDDNQALIWD 298
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGK-LLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 21-298 4.71e-17

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 80.07  E-value: 4.71e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  21 PLYSMNWSvrPDKRFrLALGSfveeYNNKVQIVSLDEETSEFSAKStfdHPYPTTKIMWIPDSKglfpdLLATSGD--YL 98
Cdd:cd00200    11 GVTCVAFS--PDGKL-LATGS----GDGTIKVWDLETGELLRTLKG---HTGPVRDVAASADGT-----YLASGSSdkTI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  99 RVWRAAEPE--TRLECvlnnnknsdFCAPLTSFDWNeVDPNLIGTSSIDTTCTIWGLETGQVL-------GRVNMV---- 165
Cdd:cd00200    76 RLWDLETGEcvRTLTG---------HTSYVSSVAFS-PDGRILSSSSRDKTIKVWDVETGKCLttlrghtDWVNSVafsp 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 166 --------------------TGHVKTQLIAHDKEVYDIAFSraGGGRDMFASvGADGSVRMFDLRHLEHSTIIyedPQHT 225
Cdd:cd00200   146 dgtfvasssqdgtiklwdlrTGKCVATLTGHTGEVNSVAFS--PDGEKLLSS-SSDGTIKLWDLSTGKCLGTL---RGHE 219

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2296769121 226 -PLLRLAWNkQDPNYLATVAMDaCEVIILDVRvPCTPVARLSNHRASVNGIAWAPhSSCHICTAGDDNQALIWD 298
Cdd:cd00200   220 nGVNSVAFS-PDGYLLASGSED-GTIRVWDLR-TGECVQTLSGHTNSVTSLAWSP-DGKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
70-300 2.41e-16

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 79.18  E-value: 2.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  70 HPYPTTKIMWIPDSKglfpdLLATSGDY--LRVWRAAEPETRLecVLNNNKNsdfcaPLTSFDWNEvDPNLIGTSSIDTT 147
Cdd:COG2319   161 HSGAVTSVAFSPDGK-----LLASGSDDgtVRLWDLATGKLLR--TLTGHTG-----AVRSVAFSP-DGKLLASGSADGT 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 148 CTIWGLETGQVLGRvnmvtghvktqLIAHDKEVYDIAFSRAGggrDMFASVGADGSVRMFDLRHLEHSTIIyeDPQHTPL 227
Cdd:COG2319   228 VRLWDLATGKLLRT-----------LTGHSGSVRSVAFSPDG---RLLASGSADGTVRLWDLATGELLRTL--TGHSGGV 291

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2296769121 228 LRLAWNKqDPNYLATVAMDAcEVIILDVRVPcTPVARLSNHRASVNGIAWAPHSScHICTAGDDNQALIWDIQ 300
Cdd:COG2319   292 NSVAFSP-DGKLLASGSDDG-TVRLWDLATG-KLLRTLTGHTGAVRSVAFSPDGK-TLASGSDDGTVRLWDLA 360
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 124-300 7.92e-16

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 76.60  E-value: 7.92e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 124 APLTSFDWNEvDPNLIGTSSIDTTCTIWGLETGQVLGR-------------------------------VNMVTGHVKTQ 172
Cdd:cd00200    10 GGVTCVAFSP-DGKLLATGSGDGTIKVWDLETGELLRTlkghtgpvrdvaasadgtylasgssdktirlWDLETGECVRT 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 173 LIAHDKEVYDIAFSRAGggrDMFASVGADGSVRMFDLRHLEHSTIIyedPQHT-PLLRLAWNkQDPNYLATVAMDACeVI 251
Cdd:cd00200    89 LTGHTSYVSSVAFSPDG---RILSSSSRDKTIKVWDVETGKCLTTL---RGHTdWVNSVAFS-PDGTFVASSSQDGT-IK 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2296769121 252 ILDVRvPCTPVARLSNHRASVNGIAWAPhSSCHICTAGDDNQALIWDIQ 300
Cdd:cd00200   161 LWDLR-TGKCVATLTGHTGEVNSVAFSP-DGEKLLSSSSDGTIKLWDLS 207
WD40 COG2319
WD40 repeat [General function prediction only];
20-300 2.52e-14

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 73.41  E-value: 2.52e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  20 WPLYSMNWSvrPDKRfRLALGSfveeYNNKVQIVSLD--EETSEFSAkstfdHPYPTTKIMWIPDSKglfpdLLATSGD- 96
Cdd:COG2319   163 GAVTSVAFS--PDGK-LLASGS----DDGTVRLWDLAtgKLLRTLTG-----HTGAVRSVAFSPDGK-----LLASGSAd 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121  97 -YLRVWRAAEPEtrLECVLNNNKNSdfcapLTSFDWNEvDPNLIGTSSIDTTCTIWGLETGQVLGRvnmvtghvktqLIA 175
Cdd:COG2319   226 gTVRLWDLATGK--LLRTLTGHSGS-----VRSVAFSP-DGRLLASGSADGTVRLWDLATGELLRT-----------LTG 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 176 HDKEVYDIAFSRAGggrDMFASVGADGSVRMFDLRHLEhstIIYEDPQHT-PLLRLAWNkQDPNYLATVAMDaCEVIILD 254
Cdd:COG2319   287 HSGGVNSVAFSPDG---KLLASGSDDGTVRLWDLATGK---LLRTLTGHTgAVRSVAFS-PDGKTLASGSDD-GTVRLWD 358

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 2296769121 255 VRVPcTPVARLSNHRASVNGIAWAPHSScHICTAGDDNQALIWDIQ 300
Cdd:COG2319   359 LATG-ELLRTLTGHTGAVTSVAFSPDGR-TLASGSADGTVRLWDLA 402
WD40 COG2319
WD40 repeat [General function prediction only];
135-300 8.98e-13

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 68.78  E-value: 8.98e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 135 DPNLIGTSSIDTTCTIWGLETGQVLgrvnmvtghvkTQLIAHDKEVYDIAFSRAGggrDMFASVGADGSVRMFDLRHLEH 214
Cdd:COG2319    89 DGRLLASASADGTVRLWDLATGLLL-----------RTLTGHTGAVRSVAFSPDG---KTLASGSADGTVRLWDLATGKL 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2296769121 215 STIIyedPQHTPLLR-LAWNkQDPNYLATVAMDAcEVIILDVRVPcTPVARLSNHRASVNGIAWAPHSScHICTAGDDNQ 293
Cdd:COG2319   155 LRTL---TGHSGAVTsVAFS-PDGKLLASGSDDG-TVRLWDLATG-KLLRTLTGHTGAVRSVAFSPDGK-LLASGSADGT 227


                  ....*..
gi 2296769121 294 ALIWDIQ 300
Cdd:COG2319   228 VRLWDLA 234
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 260-298 3.00e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 40.76  E-value: 3.00e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 2296769121  260 TPVARLSNHRASVNGIAWAPHSScHICTAGDDNQALIWD 298
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGK-YLASGSDDGTIKLWD 40
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 261-336 3.23e-04

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 41.94  E-value: 3.23e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2296769121 261 PVARLSNHRASVNGIAWAPHSScHICTAGDDNQALIWDIQQMpraieDPILAYTAAEGEVNQIQWGATQpDWIAIC 336
Cdd:cd00200     1 LRRTLKGHTGGVTCVAFSPDGK-LLATGSGDGTIKVWDLETG-----ELLRTLKGHTGPVRDVAASADG-TYLASG 69
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 166-208 3.27e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.68  E-value: 3.27e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2296769121  166 TGHVKTQLIAHDKEVYDIAFSRAGggrDMFASVGADGSVRMFD 208
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDG---KYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
260-298 6.61e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 36.94  E-value: 6.61e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2296769121 260 TPVARLSNHRASVNGIAWAPHSScHICTAGDDNQALIWD 298
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGK-LLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
167-208 5.44e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 34.24  E-value: 5.44e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2296769121 167 GHVKTQLIAHDKEVYDIAFSRAGggrDMFASVGADGSVRMFD 208
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDG---KLLASGSDDGTVKVWD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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