NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2462551705|ref|XP_054170356|]
View 

zinc finger protein 276 isoform X6 [Homo sapiens]

Protein Classification

zinc-finger associated domain-containing protein( domain architecture ID 10544311)

zinc-finger associated domain (ZAD)-containing protein similar to Drosophila melanogaster zinc finger protein hangover, zinc finger protein kipf and protein phyllopod

CATH:  3.40.1800.20
Gene Ontology:  GO:0008270
SCOP:  4001830

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
78-160 2.20e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


:

Pssm-ID: 462262  Cd Length: 75  Bit Score: 50.53  E-value: 2.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462551705  78 HCRLCHgkFSSRSLRSISErapgasmerPSAEERVLVRDFQRLLGVAVRQDPTLSPFVCKSCHAQFYQCHsllkSFLQRV 157
Cdd:pfam07776   1 VCRLCL--DESDELIPIFD---------PSDSEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFY----SFRERC 65

                  ...
gi 2462551705 158 NAS 160
Cdd:pfam07776  66 LES 68
 
Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
78-160 2.20e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 50.53  E-value: 2.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462551705  78 HCRLCHgkFSSRSLRSISErapgasmerPSAEERVLVRDFQRLLGVAVRQDPTLSPFVCKSCHAQFYQCHsllkSFLQRV 157
Cdd:pfam07776   1 VCRLCL--DESDELIPIFD---------PSDSEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFY----SFRERC 65

                  ...
gi 2462551705 158 NAS 160
Cdd:pfam07776  66 LES 68
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
79-155 7.82e-06

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 43.27  E-value: 7.82e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462551705   79 CRLCHGkfSSRSLRSISERAPGASmerpsaeervLVRDFQRLLGVAVRQDPTLSPFVCKSCHAQFYQCHSLLKSFLQ 155
Cdd:smart00868   2 CRLCLS--ESENLVSIFDESSEAS----------LAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRE 66
 
Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
78-160 2.20e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 50.53  E-value: 2.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462551705  78 HCRLCHgkFSSRSLRSISErapgasmerPSAEERVLVRDFQRLLGVAVRQDPTLSPFVCKSCHAQFYQCHsllkSFLQRV 157
Cdd:pfam07776   1 VCRLCL--DESDELIPIFD---------PSDSEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFY----SFRERC 65

                  ...
gi 2462551705 158 NAS 160
Cdd:pfam07776  66 LES 68
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
79-155 7.82e-06

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 43.27  E-value: 7.82e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462551705   79 CRLCHGkfSSRSLRSISERAPGASmerpsaeervLVRDFQRLLGVAVRQDPTLSPFVCKSCHAQFYQCHSLLKSFLQ 155
Cdd:smart00868   2 CRLCLS--ESENLVSIFDESSEAS----------LAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRE 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH