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Conserved domains on  [gi|2462559931|ref|XP_054174339|]
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microtubule cross-linking factor 1 isoform X9 [Homo sapiens]

Protein Classification

SOGA and DUF4482 domain-containing protein( domain architecture ID 13530637)

protein containing domains SMC_prok_B, SOGA, and DUF4482

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SOGA pfam11365
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ...
527-621 2.33e-38

Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.


:

Pssm-ID: 463264 [Multi-domain]  Cd Length: 95  Bit Score: 138.97  E-value: 2.33e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  527 DSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANI 606
Cdd:pfam11365    1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSDSSREAELQEELKLARLQINE 80
                           90
                   ....*....|....*
gi 2462559931  607 LGRKIVELEVENRGL 621
Cdd:pfam11365   81 LSGKVMKLQYENRVL 95
SOGA pfam11365
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ...
656-748 5.68e-38

Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.


:

Pssm-ID: 463264 [Multi-domain]  Cd Length: 95  Bit Score: 137.81  E-value: 5.68e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  656 SSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREPGWLGEGASPGA--GGGAPLQEELKSARLQISE 733
Cdd:pfam11365    1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSdsSREAELQEELKLARLQINE 80
                           90
                   ....*....|....*
gi 2462559931  734 LSGKVLKLQHENHAL 748
Cdd:pfam11365   81 LSGKVMKLQYENRVL 95
DUF4482 pfam14818
Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately ...
1295-1390 7.35e-36

Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with pfam11365.


:

Pssm-ID: 464333 [Multi-domain]  Cd Length: 138  Bit Score: 133.27  E-value: 7.35e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931 1295 MDLRWQIHHSEKNWNREKVELLDRLDRDRQEWERQKKEFLWRIEQ----------------------------------- 1339
Cdd:pfam14818    1 MDLRWQLQHTEKNWHREKMELLDRFDRERQEWESQKKIMQKKIEQlqrevslrrkinmnerakvidgekfvpdqkesssp 80
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462559931 1340 -----GSLRMPR--PVAMWPCADADSIPFEDRPLSKLKESDRCSASENLYLDALSLDD 1390
Cdd:pfam14818   81 pfpdsGQCEFPRmnHPGSLSKSDSDEESFLDEGNQKLKEQKRCKASENLFLDALSLDN 138
PHA03247 super family cl33720
large tegument protein UL36; Provisional
12-326 2.31e-14

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 79.60  E-value: 2.31e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   12 APDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFL----KDLHARPAAPGPAVP---------SSGRAPAPAAPRSP 78
Cdd:PHA03247  2563 APDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRApvddRGDPRGPAPPSPLPPdthapdpppPSPSPAANEPDPHP 2642
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   79 NLAGKAPPSPGSLAAPGRLSR----RSGGVPGAKDKPPpgagaraaggakaALGSRRAARvAPAEPLSRAGKPPGAEPPS 154
Cdd:PHA03247  2643 PPTVPPPERPRDDPAPGRVSRprraRRLGRAAQASSPP-------------QRPRRRAAR-PTVGSLTSLADPPPPPPTP 2708
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  155 AAAKgRKVKRGSRAPP----ARTVGPPTPAARIPAVTLAVTSVAGSPARCSRiSHTDSSSDLSDCPSEPLSDEQRLLPAA 230
Cdd:PHA03247  2709 EPAP-HALVSATPLPPgpaaARQASPALPAAPAPPAVPAGPATPGGPARPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  231 SSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVS------GGFAGPGvaEDVRG 304
Cdd:PHA03247  2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPppslplGGSVAPG--GDVRR 2864
                          330       340
                   ....*....|....*....|....
gi 2462559931  305 RSPPERPV--PGTPKEPSLGEQSR 326
Cdd:PHA03247  2865 RPPSRSPAakPAAPARPPVRRLAR 2888
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
353-682 2.12e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.70  E-value: 2.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  353 ELDELRAEMEEMRDSY---------LEEDVYQLQE----LRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIR 419
Cdd:TIGR02168  678 EIEELEEKIEELEEKIaelekalaeLRKELEELEEeleqLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  420 SLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKtfnq 499
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI---- 833
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  500 qnggmerpgncrpatKTQRKLAPRRKDDSADLRCQLQFAKEEaflmrkkMAKLGREKDELEQELQKYKSLYGDVDSPLpt 579
Cdd:TIGR02168  834 ---------------AATERRLEDLEEQIEELSEDIESLAAE-------IEELEELIEELESELEALLNERASLEEAL-- 889
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  580 geaggppstreAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLEsstE 659
Cdd:TIGR02168  890 -----------ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---E 955
                          330       340
                   ....*....|....*....|...
gi 2462559931  660 LRRHLQFVEEEAELLRRSISEIE 682
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLE 978
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1197-1372 3.71e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931 1197 KQVVENQQ-LFSAFKALLEDFRAELREDERARLRLQ---QQYASDKAAWDVEWAVLKCRLEQLEEKTENKLGELGSSAES 1272
Cdd:TIGR02168  788 EAQIEQLKeELKALREALDELRAELTLLNEEAANLRerlESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931 1273 KGALKKEREVHQKLLADSHSLVMDLRWQIH---HSEKNWNREKVELLDRLDRDRQEWER-------------QKKEFLWr 1336
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEelsEELRELESKRSELRRELEELREKLAQlelrleglevridNLQERLS- 946
                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 2462559931 1337 iEQGSLRMPRPVAMWPCADADSIPFEDRpLSKLKES 1372
Cdd:TIGR02168  947 -EEYSLTLEEAEALENKIEDDEEEARRR-LKRLENK 980
 
Name Accession Description Interval E-value
SOGA pfam11365
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ...
527-621 2.33e-38

Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.


Pssm-ID: 463264 [Multi-domain]  Cd Length: 95  Bit Score: 138.97  E-value: 2.33e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  527 DSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANI 606
Cdd:pfam11365    1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSDSSREAELQEELKLARLQINE 80
                           90
                   ....*....|....*
gi 2462559931  607 LGRKIVELEVENRGL 621
Cdd:pfam11365   81 LSGKVMKLQYENRVL 95
SOGA pfam11365
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ...
656-748 5.68e-38

Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.


Pssm-ID: 463264 [Multi-domain]  Cd Length: 95  Bit Score: 137.81  E-value: 5.68e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  656 SSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREPGWLGEGASPGA--GGGAPLQEELKSARLQISE 733
Cdd:pfam11365    1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSdsSREAELQEELKLARLQINE 80
                           90
                   ....*....|....*
gi 2462559931  734 LSGKVLKLQHENHAL 748
Cdd:pfam11365   81 LSGKVMKLQYENRVL 95
DUF4482 pfam14818
Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately ...
1295-1390 7.35e-36

Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with pfam11365.


Pssm-ID: 464333 [Multi-domain]  Cd Length: 138  Bit Score: 133.27  E-value: 7.35e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931 1295 MDLRWQIHHSEKNWNREKVELLDRLDRDRQEWERQKKEFLWRIEQ----------------------------------- 1339
Cdd:pfam14818    1 MDLRWQLQHTEKNWHREKMELLDRFDRERQEWESQKKIMQKKIEQlqrevslrrkinmnerakvidgekfvpdqkesssp 80
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462559931 1340 -----GSLRMPR--PVAMWPCADADSIPFEDRPLSKLKESDRCSASENLYLDALSLDD 1390
Cdd:pfam14818   81 pfpdsGQCEFPRmnHPGSLSKSDSDEESFLDEGNQKLKEQKRCKASENLFLDALSLDN 138
PHA03247 PHA03247
large tegument protein UL36; Provisional
12-326 2.31e-14

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 79.60  E-value: 2.31e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   12 APDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFL----KDLHARPAAPGPAVP---------SSGRAPAPAAPRSP 78
Cdd:PHA03247  2563 APDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRApvddRGDPRGPAPPSPLPPdthapdpppPSPSPAANEPDPHP 2642
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   79 NLAGKAPPSPGSLAAPGRLSR----RSGGVPGAKDKPPpgagaraaggakaALGSRRAARvAPAEPLSRAGKPPGAEPPS 154
Cdd:PHA03247  2643 PPTVPPPERPRDDPAPGRVSRprraRRLGRAAQASSPP-------------QRPRRRAAR-PTVGSLTSLADPPPPPPTP 2708
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  155 AAAKgRKVKRGSRAPP----ARTVGPPTPAARIPAVTLAVTSVAGSPARCSRiSHTDSSSDLSDCPSEPLSDEQRLLPAA 230
Cdd:PHA03247  2709 EPAP-HALVSATPLPPgpaaARQASPALPAAPAPPAVPAGPATPGGPARPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  231 SSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVS------GGFAGPGvaEDVRG 304
Cdd:PHA03247  2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPppslplGGSVAPG--GDVRR 2864
                          330       340
                   ....*....|....*....|....
gi 2462559931  305 RSPPERPV--PGTPKEPSLGEQSR 326
Cdd:PHA03247  2865 RPPSRSPAakPAAPARPPVRRLAR 2888
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
353-682 2.12e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.70  E-value: 2.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  353 ELDELRAEMEEMRDSY---------LEEDVYQLQE----LRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIR 419
Cdd:TIGR02168  678 EIEELEEKIEELEEKIaelekalaeLRKELEELEEeleqLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  420 SLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKtfnq 499
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI---- 833
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  500 qnggmerpgncrpatKTQRKLAPRRKDDSADLRCQLQFAKEEaflmrkkMAKLGREKDELEQELQKYKSLYGDVDSPLpt 579
Cdd:TIGR02168  834 ---------------AATERRLEDLEEQIEELSEDIESLAAE-------IEELEELIEELESELEALLNERASLEEAL-- 889
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  580 geaggppstreAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLEsstE 659
Cdd:TIGR02168  890 -----------ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---E 955
                          330       340
                   ....*....|....*....|...
gi 2462559931  660 LRRHLQFVEEEAELLRRSISEIE 682
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLE 978
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
352-568 2.08e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  352 DELDELRAEMEEMRDSY--LEedvyQLQELRRELDRANKNCRILQYRLRKAEqkslkvAETGQVDGELIRSLEQDLKVAK 429
Cdd:COG4913    235 DDLERAHEALEDAREQIelLE----PIRELAERYAAARERLAELEYLRAALR------LWFAQRRLELLEAELEELRAEL 304
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  430 DvsvRLHHELKTVEEKRAKAEDENETLRQQMIEVE-ISKQALQNELERLKESSLKRRSTREMYKEKktfnQQNGGMERPG 508
Cdd:COG4913    305 A---RLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEAL----LAALGLPLPA 377
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  509 NcRPATKTQRKLAPRRKDDSADLRCQLQfakEEAFLMRKKMAKLGREKDELEQELQKYKS 568
Cdd:COG4913    378 S-AEEFAALRAEAAALLEALEEELEALE---EALAEAEAALRDLRRELRELEAEIASLER 433
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
350-568 1.99e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 56.27  E-value: 1.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDsyleedvyqlqELRRELDRANKNCRILQYRLRKAEqKSLKVAETG------QVD--GELIRSL 421
Cdd:pfam05483  546 LRDELESVREEFIQKGD-----------EVKCKLDKSEENARSIEYEVLKKE-KQMKILENKcnnlkkQIEnkNKNIEEL 613
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQAlQNELERLKESSLkrrsTREMYKEKKTFNQqn 501
Cdd:pfam05483  614 HQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQK-EIEDKKISEEKL----LEEVEKAKAIADE-- 686
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462559931  502 ggmerpgncrpATKTQRKLaprrkddsaDLRCQLQFAkEEAFLMRKKMAKLGREKDELEQELQKYKS 568
Cdd:pfam05483  687 -----------AVKLQKEI---------DKRCQHKIA-EMVALMEKHKHQYDKIIEERDSELGLYKN 732
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
350-696 5.78e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 5.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDRANKNCRILQYRLR---------KAEQKSL--KVAETGQVDG--- 415
Cdd:PRK03918   219 LREELEKLEKEVKE-----LEELKEEIEELEKELESLEGSKRKLEEKIReleerieelKKEIEELeeKVKELKELKEkae 293
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  416 ---ELIRSLEQDLKVAKDVSVRL---HHELKTVEEKRAKAEDENETLRqqmiEVEISKQALQNELERLKESSlkrrstrE 489
Cdd:PRK03918   294 eyiKLSEFYEEYLDELREIEKRLsrlEEEINGIEERIKELEEKEERLE----ELKKKLKELEKRLEELEERH-------E 362
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  490 MYKEKKTFNQQNGGMERPGNCRPATKTQRKLAPRRKddsadlrcqlqfAKEEaflMRKKMAKLGREKDELEQELQKYKSL 569
Cdd:PRK03918   363 LYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEK------------AKEE---IEEEISKITARIGELKKEIKELKKA 427
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  570 YGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIvELEVENRGLKAEMEDMRGQQEREgpgRDHAPSIPTSP 649
Cdd:PRK03918   428 IEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELK-EIEEKERKLRKELRELEKVLKKE---SELIKLKELAE 503
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 2462559931  650 FGDSLESSTEL--RRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFK 696
Cdd:PRK03918   504 QLKELEEKLKKynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE 552
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
13-319 2.27e-04

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 46.21  E-value: 2.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   13 PDAKLQPPGQHHRHHHLHPVAERrrLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLA 92
Cdd:COG5180    158 SDPILAKDPDGDSASTLPPPAEK--LDKVLTEPRDALKDSPEKLDRPKVEVKDEAQEEPPDLTGGADHPRPEAASSPKVD 235
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   93 APGRLSRRSGgvPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAA-AKGRKVKRGSRAPPA 171
Cdd:COG5180    236 PPSTSEARSR--PATVDAQPEMRPPADAKERRRAAIGDTPAAEPPGLPVLEAGSEPQSDAPEAEtARPIDVKGVASAPPA 313
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  172 RTVGPPTPAAR---IPAVTLAVTSVAGSPARCSRISHTDSSSDlsdcPSEPLSDEQRLLPAASSDAESGTGSSDREPPRG 248
Cdd:COG5180    314 TRPVRPPGGARdpgTPRPGQPTERPAGVPEAASDAGQPPSAYP----PAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNG 389
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462559931  249 APTPSPaARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAedvrgRSPPERPVPGTPKEP 319
Cdd:COG5180    390 APQPGL-GRRGAPGPPMGAGDLVQAALDGGGRETASLGGAAGGAGQGPKAD-----FVPGDAESVSGPAGL 454
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1197-1372 3.71e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931 1197 KQVVENQQ-LFSAFKALLEDFRAELREDERARLRLQ---QQYASDKAAWDVEWAVLKCRLEQLEEKTENKLGELGSSAES 1272
Cdd:TIGR02168  788 EAQIEQLKeELKALREALDELRAELTLLNEEAANLRerlESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931 1273 KGALKKEREVHQKLLADSHSLVMDLRWQIH---HSEKNWNREKVELLDRLDRDRQEWER-------------QKKEFLWr 1336
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEelsEELRELESKRSELRRELEELREKLAQlelrleglevridNLQERLS- 946
                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 2462559931 1337 iEQGSLRMPRPVAMWPCADADSIPFEDRpLSKLKES 1372
Cdd:TIGR02168  947 -EEYSLTLEEAEALENKIEDDEEEARRR-LKRLENK 980
 
Name Accession Description Interval E-value
SOGA pfam11365
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ...
527-621 2.33e-38

Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.


Pssm-ID: 463264 [Multi-domain]  Cd Length: 95  Bit Score: 138.97  E-value: 2.33e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  527 DSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANI 606
Cdd:pfam11365    1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSDSSREAELQEELKLARLQINE 80
                           90
                   ....*....|....*
gi 2462559931  607 LGRKIVELEVENRGL 621
Cdd:pfam11365   81 LSGKVMKLQYENRVL 95
SOGA pfam11365
Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, ...
656-748 5.68e-38

Protein SOGA; The SOGA (suppressor of glucose by autophagy) family consists of proteins SOGA1, SOGA2, and SOGA3. SOGA1 regulates autophagy by playing a role in the reduction of glucose production in an adiponectin and insulin dependent manner.


Pssm-ID: 463264 [Multi-domain]  Cd Length: 95  Bit Score: 137.81  E-value: 5.68e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  656 SSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREPGWLGEGASPGA--GGGAPLQEELKSARLQISE 733
Cdd:pfam11365    1 SSAELRRQLQFVEEEAELLRRSLSEIEDHNKQLTNELNKYKSKYGPDESSLSDGEGGGSdsSREAELQEELKLARLQINE 80
                           90
                   ....*....|....*
gi 2462559931  734 LSGKVLKLQHENHAL 748
Cdd:pfam11365   81 LSGKVMKLQYENRVL 95
DUF4482 pfam14818
Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately ...
1295-1390 7.35e-36

Domain of unknown function (DUF4482); This family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with pfam11365.


Pssm-ID: 464333 [Multi-domain]  Cd Length: 138  Bit Score: 133.27  E-value: 7.35e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931 1295 MDLRWQIHHSEKNWNREKVELLDRLDRDRQEWERQKKEFLWRIEQ----------------------------------- 1339
Cdd:pfam14818    1 MDLRWQLQHTEKNWHREKMELLDRFDRERQEWESQKKIMQKKIEQlqrevslrrkinmnerakvidgekfvpdqkesssp 80
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462559931 1340 -----GSLRMPR--PVAMWPCADADSIPFEDRPLSKLKESDRCSASENLYLDALSLDD 1390
Cdd:pfam14818   81 pfpdsGQCEFPRmnHPGSLSKSDSDEESFLDEGNQKLKEQKRCKASENLFLDALSLDN 138
PHA03247 PHA03247
large tegument protein UL36; Provisional
12-326 2.31e-14

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 79.60  E-value: 2.31e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   12 APDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFL----KDLHARPAAPGPAVP---------SSGRAPAPAAPRSP 78
Cdd:PHA03247  2563 APDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRApvddRGDPRGPAPPSPLPPdthapdpppPSPSPAANEPDPHP 2642
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   79 NLAGKAPPSPGSLAAPGRLSR----RSGGVPGAKDKPPpgagaraaggakaALGSRRAARvAPAEPLSRAGKPPGAEPPS 154
Cdd:PHA03247  2643 PPTVPPPERPRDDPAPGRVSRprraRRLGRAAQASSPP-------------QRPRRRAAR-PTVGSLTSLADPPPPPPTP 2708
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  155 AAAKgRKVKRGSRAPP----ARTVGPPTPAARIPAVTLAVTSVAGSPARCSRiSHTDSSSDLSDCPSEPLSDEQRLLPAA 230
Cdd:PHA03247  2709 EPAP-HALVSATPLPPgpaaARQASPALPAAPAPPAVPAGPATPGGPARPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  231 SSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVS------GGFAGPGvaEDVRG 304
Cdd:PHA03247  2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPppslplGGSVAPG--GDVRR 2864
                          330       340
                   ....*....|....*....|....
gi 2462559931  305 RSPPERPV--PGTPKEPSLGEQSR 326
Cdd:PHA03247  2865 RPPSRSPAakPAAPARPPVRRLAR 2888
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
353-682 2.12e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.70  E-value: 2.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  353 ELDELRAEMEEMRDSY---------LEEDVYQLQE----LRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIR 419
Cdd:TIGR02168  678 EIEELEEKIEELEEKIaelekalaeLRKELEELEEeleqLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  420 SLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKtfnq 499
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI---- 833
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  500 qnggmerpgncrpatKTQRKLAPRRKDDSADLRCQLQFAKEEaflmrkkMAKLGREKDELEQELQKYKSLYGDVDSPLpt 579
Cdd:TIGR02168  834 ---------------AATERRLEDLEEQIEELSEDIESLAAE-------IEELEELIEELESELEALLNERASLEEAL-- 889
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  580 geaggppstreAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLEsstE 659
Cdd:TIGR02168  890 -----------ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---E 955
                          330       340
                   ....*....|....*....|...
gi 2462559931  660 LRRHLQFVEEEAELLRRSISEIE 682
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLE 978
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
7-316 1.64e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 66.73  E-value: 1.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931    7 PAGGGAPDAklqPPGQHHRHHHLHPVAERRRLHRAPSPA-RPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAP 85
Cdd:PHA03307   122 PPASPPPSP---APDLSEMLRPVGSPGPPPAASPPAAGAsPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTP 198
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   86 PSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSR-RAARVAPAEPLSRAGKPPGAEPPSAAAKGRKVKR 164
Cdd:PHA03307   199 PAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSEsSGCGWGPENECPLPRPAPITLPTRIWEASGWNGP 278
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  165 GSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDRE 244
Cdd:PHA03307   279 SSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPP 358
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462559931  245 PPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGP-----GVAEDVRGRSPPERPVPGTP 316
Cdd:PHA03307   359 PADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGrprpsPLDAGAASGAFYARYPLLTP 435
PHA03247 PHA03247
large tegument protein UL36; Provisional
10-319 2.80e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.65  E-value: 2.80e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   10 GGAPDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPG 89
Cdd:PHA03247  2639 DPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSA 2718
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   90 SLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAAR---VAPAEPLSRAGKPPGAEPPSAAAKGRKVKRGS 166
Cdd:PHA03247  2719 TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTagpPAPAPPAAPAAGPPRRLTRPAVASLSESRESL 2798
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  167 RAPPARTVGPPTPAARIPAVTLAVTSVAGSPArcsrishtdSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSsdREPP 246
Cdd:PHA03247  2799 PSPWDPADPPAAVLAPAAALPPAASPAGPLPP---------PTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVR--RRPP 2867
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462559931  247 RGAPTPSPAARGAPPGSPEPPALLAAPLAAGACP--GGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEP 319
Cdd:PHA03247  2868 SRSPAAKPAAPARPPVRRLARPAVSRSTESFALPpdQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
39-320 3.78e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 62.11  E-value: 3.78e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   39 HRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLS--RRSGGVPGAKDKPPPGAG 116
Cdd:PHA03307    77 TEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEmlRPVGSPGPPPAASPPAAG 156
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  117 ARAAGGAKAALGSRRAARVAP-AEPLSRAGKPPGAEPPSAAakgrkvkrgSRAPPARTVGPPTPAARIPAVTLAVTSVAG 195
Cdd:PHA03307   157 ASPAAVASDAASSRQAALPLSsPEETARAPSSPPAEPPPST---------PPAAASPRPPRRSSPISASASSPAPAPGRS 227
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  196 SPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPA-----ASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALL 270
Cdd:PHA03307   228 AADDAGASSSDSSSSESSGCGWGPENECPLPRPApitlpTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGP 307
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462559931  271 AAPLAAGACPGGRSIPSGVSGGFAGPGVAEDV---RGRSPPERPVPGTPKEPS 320
Cdd:PHA03307   308 APSSPRASSSSSSSRESSSSSTSSSSESSRGAavsPGPSPSRSPSPSRPPPPA 360
PHA03247 PHA03247
large tegument protein UL36; Provisional
8-330 6.49e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.49  E-value: 6.49e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931    8 AGGGAPDAKLQPPGQHHRHHHLHPVAERRRlHRAPSPARPflkdlharPAAPGPAVPSSGRapapaaprspnlAGKAPPS 87
Cdd:PHA03247  2728 ARQASPALPAAPAPPAVPAGPATPGGPARP-ARPPTTAGP--------PAPAPPAAPAAGP------------PRRLTRP 2786
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   88 PGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAA-AKGRKVKRgs 166
Cdd:PHA03247  2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSvAPGGDVRR-- 2864
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  167 RAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAEsgtgssdrePP 246
Cdd:PHA03247  2865 RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP---------PP 2935
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  247 RGAPTPSPAARGAPPGSPEppallaaplAAGACPGGRSipsgvsgGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSR 326
Cdd:PHA03247  2936 PPRPQPPLAPTTDPAGAGE---------PSGAVPQPWL-------GALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGH 2999

                   ....
gi 2462559931  327 LVPA 330
Cdd:PHA03247  3000 SLSR 3003
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
352-568 2.08e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  352 DELDELRAEMEEMRDSY--LEedvyQLQELRRELDRANKNCRILQYRLRKAEqkslkvAETGQVDGELIRSLEQDLKVAK 429
Cdd:COG4913    235 DDLERAHEALEDAREQIelLE----PIRELAERYAAARERLAELEYLRAALR------LWFAQRRLELLEAELEELRAEL 304
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  430 DvsvRLHHELKTVEEKRAKAEDENETLRQQMIEVE-ISKQALQNELERLKESSLKRRSTREMYKEKktfnQQNGGMERPG 508
Cdd:COG4913    305 A---RLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEAL----LAALGLPLPA 377
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  509 NcRPATKTQRKLAPRRKDDSADLRCQLQfakEEAFLMRKKMAKLGREKDELEQELQKYKS 568
Cdd:COG4913    378 S-AEEFAALRAEAAALLEALEEELEALE---EALAEAEAALRDLRRELRELEAEIASLER 433
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
353-568 2.73e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 2.73e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  353 ELDELRAEMEEMRDsylEEDVYQ--LQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQ-------VDGELIRSLEQ 423
Cdd:TIGR02168  268 KLEELRLEVSELEE---EIEELQkeLYALANEISRLEQQKQILRERLANLERQLEELEAQLEeleskldELAEELAELEE 344
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  424 DLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQM-------IEVEISKQALQNELERLKE--SSLKRRSTRemykek 494
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLetlrskvAQLELQIASLNNEIERLEArlERLEDRRER------ 418
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462559931  495 ktfNQQNGGMERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKS 568
Cdd:TIGR02168  419 ---LQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
350-688 3.19e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.63  E-value: 3.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDSYLE--------EDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETgqvdGELIRSL 421
Cdd:COG4717     93 LQEELEELEEELEELEAELEElreeleklEKLLQLLPLYQELEALEAELAELPERLEELEERLEELREL----EEELEEL 168
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  422 EQDLKVAK--------DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKE 493
Cdd:COG4717    169 EAELAELQeeleelleQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEA 248
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  494 KKTFNQQNGGMERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGR--EKDELEQ-ELQKYKSLY 570
Cdd:COG4717    249 RLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAlpALEELEEeELEELLAAL 328
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  571 GdVDSPLPTGEAGGPPST-----------REAELKLRLKLVEEEANILG-----------RKIVELEVENRGLKAEMEDM 628
Cdd:COG4717    329 G-LPPDLSPEELLELLDRieelqellreaEELEEELQLEELEQEIAALLaeagvedeeelRAALEQAEEYQELKEELEEL 407
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462559931  629 RGQQEREGPGRDHAPSIPTspfGDSLES-STELRRHLQFVEEEAELLRRSISEIEDHNRQL 688
Cdd:COG4717    408 EEQLEELLGELEELLEALD---EEELEEeLEELEEELEELEEELEELREELAELEAELEQL 465
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
351-734 6.78e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.16  E-value: 6.78e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  351 KDELDELRAEMEEMrDSYLEEDVYQLQELRRELDRANKNcRILQYRLRKAEQ----KSLKVAETG--QVDGElIRSLEQD 424
Cdd:TIGR02169  176 LEELEEVEENIERL-DLIIDEKRQQLERLRREREKAERY-QALLKEKREYEGyellKEKEALERQkeAIERQ-LASLEEE 252
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  425 LkvaKDVSVRLHHELKTVEEKRAKAEDENEtlrqqmievEISKQAlQNELERLKESSLKRRSTREMYKEKKTFNQQNggm 504
Cdd:TIGR02169  253 L---EKLTEEISELEKRLEEIEQLLEELNK---------KIKDLG-EEEQLRVKEKIGELEAEIASLERSIAEKERE--- 316
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  505 erpgncrpatktQRKLAPRRKDDSADLRCQlqfaKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLptgeagG 584
Cdd:TIGR02169  317 ------------LEDAEERLAKLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAEL------E 374
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  585 PPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMedmrgqQEREGPGRDHAPSIPtspfgDSLESSTELrrhl 664
Cdd:TIGR02169  375 EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL------QRLSEELADLNAAIA-----GIEAKINEL---- 439
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  665 qfvEEEAELLRRSISEIEDHNRQLTHELSKFKFEpprepgwlgegASPGAGGGAPLQEELKSARLQISEL 734
Cdd:TIGR02169  440 ---EEEKEDKALEIKKQEWKLEQLAADLSKYEQE-----------LYDLKEEYDRVEKELSKLQRELAEA 495
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
370-1102 1.21e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  370 EEDVYQLQELRRELDRANKNCRI-----LQYRLRKAEQKSLKVAETGQVDGELIRSLEQdLKVAKDVSVRLHHELktvEE 444
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKSLERqaekaERYKELKAELRELELALLVLRLEELREELEE-LQEELKEAEEELEEL---TA 260
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  445 KRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRRstREMYKEKKTFNQQNggmerpgncRPATKTQRKLAP 522
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANeiSRLEQQ--KQILRERLANLERQ---------LEELEAQLEELE 329
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  523 RRKD----DSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVdsplptgeaggppSTREAELKLRLK 598
Cdd:TIGR02168  330 SKLDelaeELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL-------------RSKVAQLELQIA 396
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  599 LVEEEANILGRKIVELEVENRGLKAEMEDMRGQQErEGPGRDHAPSIPTSPfgdslESSTELRRHLQFVEEEAELLRRSI 678
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQQEIEELLKKLE-EAELKELQAELEELE-----EELEELQEELERLEEALEELREEL 470
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  679 SEIEDHNRQLTHELSKFKFEpprepgwlGEGASPGAGGGAPLQEELKSARLQISELSGKVlklqhenhALLSNIQRCD-- 756
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQAR--------LDSLERLQENLEGFSEGVKALLKNQSGLSGIL--------GVLSELISVDeg 534
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  757 ----LAAHLGLRAPSPRDSDAES-----DAGKKESDGEESRLPqPKREGPVGGESDSEEMFEKTSGF-GSGKPSEASEPC 826
Cdd:TIGR02168  535 yeaaIEAALGGRLQAVVVENLNAakkaiAFLKQNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFlGVAKDLVKFDPK 613
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  827 PTELLKAREDSEYLVTLKHEAQRL---ERTVERLITDTDSFLHDAGLRGGAPLPGPGLQG------EEERGEGDQQEPQL 897
Cdd:TIGR02168  614 LRKALSYLLGGVLVVDDLDNALELakkLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerrreiEELEEKIEELEEKI 693
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  898 LgTINAKMKAFKKELQAF---LEQVNRIGDGLSPLPHLTESSSFLSTVTSVSRDSPIGNLGKELGpDLQSRLKEQLEwQL 974
Cdd:TIGR02168  694 A-ELEKALAELRKELEELeeeLEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT-ELEAEIEELEE-RL 770
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  975 GPARG------DERESL----------------RLRAARELHRRADGDTGSHGLGGQtcfSLELRgppvLPEQSVSIEEL 1032
Cdd:TIGR02168  771 EEAEEelaeaeAEIEELeaqieqlkeelkalreALDELRAELTLLNEEAANLRERLE---SLERR----IAATERRLEDL 843
                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462559931 1033 QGQL------VQAARLHQEETETFTNKIHKMEEEHLYALRWKELEMHSL--ALQNTLHE-RTWSDEKNLMQQELRSLKQ 1102
Cdd:TIGR02168  844 EEQIeelsedIESLAAEIEELEELIEELESELEALLNERASLEEALALLrsELEELSEElRELESKRSELRRELEELRE 922
PHA03247 PHA03247
large tegument protein UL36; Provisional
85-331 1.37e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.26  E-value: 1.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   85 PPSPGSLAAPGRLSRRSggVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPlsrAGKPPGAEPPSAAakgrkvkr 164
Cdd:PHA03247  2551 PPPPLPPAAPPAAPDRS--VPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDD---RGDPRGPAPPSPL-------- 2617
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  165 gsraPPARTVGPPTPAARIPAVTLA------------VTSVAGSPARCSRISHTDSSSDlsdcPSEPLSDEQRLLPAASS 232
Cdd:PHA03247  2618 ----PPDTHAPDPPPPSPSPAANEPdphppptvpppeRPRDDPAPGRVSRPRRARRLGR----AAQASSPPQRPRRRAAR 2689
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  233 DAESGTGSSDREPPRGaPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPV 312
Cdd:PHA03247  2690 PTVGSLTSLADPPPPP-PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPA 2768
                          250
                   ....*....|....*....
gi 2462559931  313 PGTPKEPSLGEQSRLVPAA 331
Cdd:PHA03247  2769 PAPPAAPAAGPPRRLTRPA 2787
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
443-795 1.69e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.61  E-value: 1.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  443 EEKRAKAEDENETLRQQMIEVEISKQALQNELERLKesslKRRSTREMYKEKKTFNQQNGGMERPGNCRPATKTQRKLAP 522
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLR----REREKAERYQALLKEKREYEGYELLKEKEALERQKEAIER 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  523 RRkddsADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSlygdvDSPLPTGEAGGPPSTREAELKLRLKLVEE 602
Cdd:TIGR02169  245 QL----ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE-----EEQLRVKEKIGELEAEIASLERSIAEKER 315
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  603 EANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHApsipTSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIE 682
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKL----TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  683 DHNRQLTHELSKFKFEPPRepgwLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQRcdLAAHLG 762
Cdd:TIGR02169  392 EKLEKLKREINELKRELDR----LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ--LAADLS 465
                          330       340       350
                   ....*....|....*....|....*....|...
gi 2462559931  763 lrapsprDSDAESDAGKKESDGEESRLPQPKRE 795
Cdd:TIGR02169  466 -------KYEQELYDLKEEYDRVEKELSKLQRE 491
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
7-264 1.77e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 56.40  E-value: 1.77e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931    7 PAGGGAPDAKLQPP---GQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGK 83
Cdd:PRK07003   362 VTGGGAPGGGVPARvagAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDD 441
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   84 APPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKVK 163
Cdd:PRK07003   442 AADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDA 521
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  164 RGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCS--RIShtdsssdlsdcpseplSDEQRLLPAASSDAESGTGSS 241
Cdd:PRK07003   522 PAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAgmRVS----------------SDRGARAAAAAKPAAAPAAAP 585
                          250       260
                   ....*....|....*....|....
gi 2462559931  242 DREPPRGA-PTPSPAARGAPPGSP 264
Cdd:PRK07003   586 KPAAPRVAvQVPTPRARAATGDAP 609
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
350-568 1.99e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 56.27  E-value: 1.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDsyleedvyqlqELRRELDRANKNCRILQYRLRKAEqKSLKVAETG------QVD--GELIRSL 421
Cdd:pfam05483  546 LRDELESVREEFIQKGD-----------EVKCKLDKSEENARSIEYEVLKKE-KQMKILENKcnnlkkQIEnkNKNIEEL 613
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQAlQNELERLKESSLkrrsTREMYKEKKTFNQqn 501
Cdd:pfam05483  614 HQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQK-EIEDKKISEEKL----LEEVEKAKAIADE-- 686
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462559931  502 ggmerpgncrpATKTQRKLaprrkddsaDLRCQLQFAkEEAFLMRKKMAKLGREKDELEQELQKYKS 568
Cdd:pfam05483  687 -----------AVKLQKEI---------DKRCQHKIA-EMVALMEKHKHQYDKIIEERDSELGLYKN 732
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
6-262 3.66e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 55.27  E-value: 3.66e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931    6 GPAGGGAPDAklqppgqhhrHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPaaprspnlAGKAP 85
Cdd:PRK12323   366 GQSGGGAGPA----------TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA--------PARRS 427
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   86 PSPGSLAAP-GRLSRRSGGVPGAKDKPPPGAgaraaggakaalgsrrAARVAPAEPLSRAGKPPGAEPPSAAAKGRKVKR 164
Cdd:PRK12323   428 PAPEALAAArQASARGPGGAPAPAPAPAAAP----------------AAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  165 GSRAPPARTVGPPTPAARIPAVTLAvtsvagSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDRE 244
Cdd:PRK12323   492 ADDDPPPWEELPPEFASPAPAQPDA------APAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRP 565
                          250
                   ....*....|....*...
gi 2462559931  245 PPRGAPTPSPAARGAPPG 262
Cdd:PRK12323   566 PRASASGLPDMFDGDWPA 583
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
133-383 4.07e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 55.38  E-value: 4.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  133 ARVAPAEPLSRAGKPPGAEPPSAAAKGRKVKRGSR-APPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSSSD 211
Cdd:PRK07764   586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAApAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  212 LSDCPSEPLSdeqrllPAASSDAESGTGSSDRePPRGAPTPSPAARGAPPGSPEPPallaaplaagacPGGRSIPSGVSG 291
Cdd:PRK07764   666 GDGWPAKAGG------AAPAAPPPAPAPAAPA-APAGAAPAQPAPAPAATPPAGQA------------DDPAAQPPQAAQ 726
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  292 GFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVPAAEEEELLREMEELRSEndylkdELDELRAEMEEMRDSYLEE 371
Cdd:PRK07764   727 GASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE------EEEMAEDDAPSMDDEDRRD 800
                          250
                   ....*....|...
gi 2462559931  372 -DVYQLQELRREL 383
Cdd:PRK07764   801 aEEVAMELLEEEL 813
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
39-317 5.37e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 55.18  E-value: 5.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   39 HRAPSPARPFLKDLHARPAA--PGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAP---GRLSRRSGGVPGAKDKP-P 112
Cdd:PHA03307   118 PPTPPPASPPPSPAPDLSEMlrPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPlssPEETARAPSSPPAEPPPsT 197
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  113 PGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKVKRGSRA-----PPARTVGPPTPAARIPAVT 187
Cdd:PHA03307   198 PPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENecplpRPAPITLPTRIWEASGWNG 277
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  188 LAVTSVAGSPARCSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARG--------- 258
Cdd:PHA03307   278 PSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSrspspsrpp 357
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462559931  259 --APPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPK 317
Cdd:PHA03307   358 ppADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLD 418
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
350-696 5.78e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 5.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDRANKNCRILQYRLR---------KAEQKSL--KVAETGQVDG--- 415
Cdd:PRK03918   219 LREELEKLEKEVKE-----LEELKEEIEELEKELESLEGSKRKLEEKIReleerieelKKEIEELeeKVKELKELKEkae 293
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  416 ---ELIRSLEQDLKVAKDVSVRL---HHELKTVEEKRAKAEDENETLRqqmiEVEISKQALQNELERLKESSlkrrstrE 489
Cdd:PRK03918   294 eyiKLSEFYEEYLDELREIEKRLsrlEEEINGIEERIKELEEKEERLE----ELKKKLKELEKRLEELEERH-------E 362
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  490 MYKEKKTFNQQNGGMERPGNCRPATKTQRKLAPRRKddsadlrcqlqfAKEEaflMRKKMAKLGREKDELEQELQKYKSL 569
Cdd:PRK03918   363 LYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEK------------AKEE---IEEEISKITARIGELKKEIKELKKA 427
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  570 YGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIvELEVENRGLKAEMEDMRGQQEREgpgRDHAPSIPTSP 649
Cdd:PRK03918   428 IEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELK-EIEEKERKLRKELRELEKVLKKE---SELIKLKELAE 503
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 2462559931  650 FGDSLESSTEL--RRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFK 696
Cdd:PRK03918   504 QLKELEEKLKKynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE 552
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
81-331 5.81e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 54.86  E-value: 5.81e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   81 AGKAPPS-PGSLAAPGrlsRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKG 159
Cdd:PRK07003   369 GGGVPARvAGAVPAPG---ARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADG 445
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  160 RKVKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARcsrishtdsssdlSDCPSEPLSdeqrllPAASSDAESGTG 239
Cdd:PRK07003   446 DAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAP-------------PDAAFEPAP------RAAAPSAATPAA 506
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  240 SSDREPPRGAPTPSPAARGAPPgSPEPPALLAAPLAAGACPGGRSIP---------------SGVSGGFAGPGVAEDVRG 304
Cdd:PRK07003   507 VPDARAPAAASREDAPAAAAPP-APEARPPTPAAAAPAARAGGAAAAldvlrnagmrvssdrGARAAAAAKPAAAPAAAP 585
                          250       260       270
                   ....*....|....*....|....*....|
gi 2462559931  305 RSPPER---PVPgTPKEPSLGEQSRLVPAA 331
Cdd:PRK07003   586 KPAAPRvavQVP-TPRARAATGDAPPNGAA 614
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
348-694 9.63e-07

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 53.37  E-value: 9.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  348 DYLKDELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKsLKVAETGQvdgeliRSLEQDLKV 427
Cdd:COG4372     41 DKLQEELEQLREELEQARE--------ELEQLEEELEQARSELEQLEEELEELNEQ-LQAAQAEL------AQAQEELES 105
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  428 AKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKEsslkrrstremykEKKTFNQQNGGMERP 507
Cdd:COG4372    106 LQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEE-------------QLESLQEELAALEQE 172
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  508 GNCRPATKTQRKLAPRRKddsaDLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPS 587
Cdd:COG4372    173 LQALSEAEAEQALDELLK----EANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDK 248
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  588 T---REAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTSPFGDSLESSTELRRHL 664
Cdd:COG4372    249 EellEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKL 328
                          330       340       350
                   ....*....|....*....|....*....|
gi 2462559931  665 QFVEEEAELLRRSISEIEDHNRQLTHELSK 694
Cdd:COG4372    329 ELALAILLAELADLLQLLLVGLLDNDVLEL 358
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
346-921 1.05e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.28  E-value: 1.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  346 ENDYLKDE----LDELRAEMEEMRD-SYLEEDVYQLQELRRelDRANKNCRILQYRLRKAEQKSLKVAE---TGQVDgEL 417
Cdd:TIGR00606  502 EVKSLQNEkadlDRKLRKLDQEMEQlNHHTTTRTQMEMLTK--DKMDKDEQIRKIKSRHSDELTSLLGYfpnKKQLE-DW 578
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  418 IRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVE------ISKQALQNELERLKESSLKRRSTREMY 491
Cdd:TIGR00606  579 LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEdklfdvCGSQDEESDLERLKEEIEKSSKQRAML 658
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  492 KEKKTFNQQ--NGGMERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSL 569
Cdd:TIGR00606  659 AGATAVYSQfiTQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSI 738
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  570 YGDVDSPLP-TGEAGGPPSTREAELKLRLklvEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGPGRDHAPSIPTS 648
Cdd:TIGR00606  739 IDLKEKEIPeLRNKLQKVNRDIQRLKNDI---EEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKL 815
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  649 PFGDSLESSTELRrhlQFVEEEAELLRRSISEIE-------DHNRQLTHELSKFKfepprepgwlgegaspgagggaplq 721
Cdd:TIGR00606  816 QGSDLDRTVQQVN---QEKQEKQHELDTVVSKIElnrkliqDQQEQIQHLKSKTN------------------------- 867
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  722 eELKSARLQISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRAPSPRDSDAESDAGKKE----SDGEESRLPQPKREgp 797
Cdd:TIGR00606  868 -ELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEelisSKETSNKKAQDKVN-- 944
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  798 vggesDSEEMFEKTSGFGSGKPSEASEPCPTELL-KAREDSEYLVTLKHEAQRLERTVERLITDTDSFlhdaglrggapl 876
Cdd:TIGR00606  945 -----DIKEKVKNIHGYMKDIENKIQDGKDDYLKqKETELNTVNAQLEECEKHQEKINEDMRLMRQDI------------ 1007
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 2462559931  877 pgpGLQGEEERGEGDQQEpqlLGTINAKMKAFKKELQAFLEQVNR 921
Cdd:TIGR00606 1008 ---DTQKIQERWLQDNLT---LRKRENELKEVEEELKQHLKEMGQ 1046
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
350-751 1.14e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.87  E-value: 1.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRD------SYLEEDVYQLQELRRELDRANKNCRILQYRLR--KAEQKSLKvaetGQVDGELIRSL 421
Cdd:TIGR04523  237 KQQEINEKTTEISNTQTqlnqlkDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNqlKSEISDLN----NQKEQDWNKEL 312
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERlKESSLKRrstreMYKEKKTFNQQN 501
Cdd:TIGR04523  313 KSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE-KQNEIEK-----LKKENQSYKQEI 386
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  502 ggmerpgncrpatktqRKLaprrKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGE 581
Cdd:TIGR04523  387 ----------------KNL----ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  582 aggppsTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMrgQQEREGPGRDHapSIPTSPFGDSLESSTELR 661
Cdd:TIGR04523  447 ------NQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQK--QKELKSKEKEL--KKLNEEKKELEEKVKDLT 516
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  662 RHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFepprepgwlgegaspgagggaplqeELKSARL--QISELSGKVL 739
Cdd:TIGR04523  517 KKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF-------------------------ELKKENLekEIDEKNKEIE 571
                          410
                   ....*....|..
gi 2462559931  740 KLQHENHALLSN 751
Cdd:TIGR04523  572 ELKQTQKSLKKK 583
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
350-635 1.51e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKslkvaetgqvdgelIRSLEQDLKVAK 429
Cdd:COG1196    258 LEAELAELEAELEELRL--------ELEELELELEEAQAEEYELLAELARLEQD--------------IARLEERRRELE 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  430 DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKtfnqqnggmerpgn 509
Cdd:COG1196    316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL-------------- 381
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  510 crpATKTQRKLAPRRkdDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVdsplptgeaggppSTR 589
Cdd:COG1196    382 ---EELAEELLEALR--AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE-------------EEA 443
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 2462559931  590 EAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERE 635
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
350-615 1.67e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDSY---------LEEDVY----QLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGE 416
Cdd:COG1196    272 LRLELEELELELEEAQAEEyellaelarLEQDIArleeRRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  417 LIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKT 496
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  497 FNQQNGGMERpgncRPATKTQRKLApRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDvdsp 576
Cdd:COG1196    432 ELEEEEEEEE----EALEEAAEEEA-ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD---- 502
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462559931  577 lptgEAGGPPSTREAELKLRLKLVEEEANILGRKIVELE 615
Cdd:COG1196    503 ----YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
346-484 1.70e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 1.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  346 ENDYLKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDL 425
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAELEEVDK-EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI 429
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462559931  426 KVAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKR 484
Cdd:TIGR02169  430 AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKelSKLQR 490
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
60-265 2.93e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 52.68  E-value: 2.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   60 GPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAE 139
Cdd:PRK07764   590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGW 669
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  140 PLSRAGKPPGAEPPSAAAKGRKVKRGSRAPPARTVGPPTPAARipavtlAVTSVAGSPARCSRISHTDSSSDLSDCPSEP 219
Cdd:PRK07764   670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAG------QADDPAAQPPQAAQGASAPSPAADDPVPLPP 743
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462559931  220 LSDEQRLLPAASSDAESGTGSSDREPPrgAPTPSPAARGAPPGSPE 265
Cdd:PRK07764   744 EPDDPPDPAGAPAQPPPPPAPAPAAAP--AAAPPPSPPSEEEEMAE 787
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
345-687 4.81e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 4.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  345 SENDYLKDELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKslkvaetgqvdgelIRSLEQD 424
Cdd:TIGR02169  695 SELRRIENRLDELSQELSDASR--------KIGEIEKEIEQLEQEEEKLKERLEELEED--------------LSSLEQE 752
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  425 LKVAKDVSVRLHHELKTVEEKRAKAEDENETL-----RQQMIEVEISKQALQNELERLK------ESSLKRRSTREMYKE 493
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEarlreiEQKLNRLTLEKEYLE 832
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  494 KKTFNQQNGgmerpgncRPATKTQRKLAPRRKDDS-ADLRCQLQFAKE-EAFL--MRKKMAKLGREKDELEQELQKYKSL 569
Cdd:TIGR02169  833 KEIQELQEQ--------RIDLKEQIKSIEKEIENLnGKKEELEEELEElEAALrdLESRLGDLKKERDELEAQLRELERK 904
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  570 YGDVDSPLPTGEaggppsTREAELKLRLKLVEEEANILGRKIVELEVEN------RGLKAEMEDMRGQQEREGPGRDHAP 643
Cdd:TIGR02169  905 IEELEAQIEKKR------KRLSELKAKLEALEEELSEIEDPKGEDEEIPeeelslEDVQAELQRVEEEIRALEPVNMLAI 978
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 2462559931  644 siptSPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHNRQ 687
Cdd:TIGR02169  979 ----QEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
350-485 4.84e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 4.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKncrilqyRLRKAEQKSLKVAetgqvdgELIRSLEQDLKVAK 429
Cdd:COG4913    314 LEARLDALREELDELEAQIRGNGGDRLEQLEREIERLER-------ELEERERRRARLE-------ALLAALGLPLPASA 379
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462559931  430 DVSVRLHHELKtveEKRAKAEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRR 485
Cdd:COG4913    380 EEFAALRAEAA---ALLEALEEELEALEEALAEAEAALRDLRRELRELEAeiASLERR 434
PTZ00121 PTZ00121
MAEBL; Provisional
351-635 6.57e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.68  E-value: 6.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  351 KDELDELRAEMEEMRDSylEEDVYQLQELRRELDRANKNCRILQY--RLRKAEQK----SLKVAETGQVDGELIRSLE-- 422
Cdd:PTZ00121  1469 AKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADEAKKAAEAKKKadEAKKAEEAkkadEAKKAEEAKKADEAKKAEEkk 1546
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  423 --QDLKVAKDVsvRLHHELKTVEEKRAKAEDENETLRQqmieVEISKQAlqnELERLKESSLKRRSTREMYKEKktFNQQ 500
Cdd:PTZ00121  1547 kaDELKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRK----AEEAKKA---EEARIEEVMKLYEEEKKMKAEE--AKKA 1615
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  501 NGGMERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFAKEEaflmRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTG 580
Cdd:PTZ00121  1616 EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE----EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA 1691
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462559931  581 EAggppSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERE 635
Cdd:PTZ00121  1692 EA----LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
350-696 6.78e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 6.78e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDRANK--------NCRILQYRLRKAEQKSLKVAETGQVDGELIRSL 421
Cdd:PRK03918   343 LKKKLKELEKRLEE-----LEERHELYEEAKAKKEELERlkkrltglTPEKLEKELEELEKAKEEIEEEISKITARIGEL 417
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  422 EQ----------DLKVAK----------------DVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVE--ISKQ----A 469
Cdd:PRK03918   418 KKeikelkkaieELKKAKgkcpvcgrelteehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvLKKEseliK 497
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  470 LQNELERLK--ESSLKRRSTREMYKEKKTF---NQQNGGMErpGNCRPATKTQRKLAPRRKdDSADLRCQLQFAKEEAFL 544
Cdd:PRK03918   498 LKELAEQLKelEEKLKKYNLEELEKKAEEYeklKEKLIKLK--GEIKSLKKELEKLEELKK-KLAELEKKLDELEEELAE 574
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  545 MRKKMAKLGREK-DELEQELQKYKSLYGDVDsplptgEAGGPPSTREAELKlRLKLVEEEANILGRKIVELEVENRGLKA 623
Cdd:PRK03918   575 LLKELEELGFESvEELEERLKELEPFYNEYL------ELKDAEKELEREEK-ELKKLEEELDKAFEELAETEKRLEELRK 647
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462559931  624 EMEDMRGQQEREgpgrdhapsiptsPFGDSLESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFK 696
Cdd:PRK03918   648 ELEELEKKYSEE-------------EYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
350-696 6.80e-06

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 51.28  E-value: 6.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEmRDSYLEEDVYQLQELRRELDRANKNCR---ILQYRLRKAeQKSLKVAEtgQVDGELIRSL---EQ 423
Cdd:pfam05557  109 LKNELSELRRQIQR-AELELQSTNSELEELQERLDLLKAKASeaeQLRQNLEKQ-QSSLAEAE--QRIKELEFEIqsqEQ 184
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  424 DLKVAKDVSV-------------RLHHELK--------------TVEEKRAKAEDEnETLRQQMIEVEISKQALQNEL-- 474
Cdd:pfam05557  185 DSEIVKNSKSelaripelekeleRLREHNKhlnenienklllkeEVEDLKRKLERE-EKYREEAATLELEKEKLEQELqs 263
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  475 -ERLKESS--------LKRRSTREMYKEKKTFNQQNGGMERpgNCRPATKTQRKLAPRRKDDSA---DLRCQLQFAKEEA 542
Cdd:pfam05557  264 wVKLAQDTglnlrspeDLSRRIEQLQQREIVLKEENSSLTS--SARQLEKARRELEQELAQYLKkieDLNKKLKRHKALV 341
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  543 FLMRKKMAKLGREKDELEQELQKYkslygdvDSPLPTGEAGGPPSTREAEL-----KLRLKLVEEEANI--LGRKIVELE 615
Cdd:pfam05557  342 RRLQRRVLLLTKERDGYRAILESY-------DKELTMSNYSPQLLERIEEAedmtqKMQAHNEEMEAQLsvAEEELGGYK 414
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  616 VENRGLKAEMEDMRGQQEREGPGRdhapsiptspfgdSLESSTELRRHLQFVEEEAELLRRSI----SEIEDHNRQLTHE 691
Cdd:pfam05557  415 QQAQTLERELQALRQQESLADPSY-------------SKEEVDSLRRKLETLELERQRLREQKneleMELERRCLQGDYD 481

                   ....*
gi 2462559931  692 LSKFK 696
Cdd:pfam05557  482 PKKTK 486
PTZ00121 PTZ00121
MAEBL; Provisional
358-567 7.97e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 7.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  358 RAEMEEMRDSYLEEDVYQLQELRREldranKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHH 437
Cdd:PTZ00121  1591 EARIEEVMKLYEEEKKMKAEEAKKA-----EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  438 ELKTVEEKRAKAEdenETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKE---KKTFNQQNGGMERPGncRPAT 514
Cdd:PTZ00121  1666 EAKKAEEDKKKAE---EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAeelKKAEEENKIKAEEAK--KEAE 1740
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462559931  515 KTQRKLAPRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYK 567
Cdd:PTZ00121  1741 EDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR 1793
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
54-313 8.51e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 51.00  E-value: 8.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   54 ARPAAPGPAVPSS-----GRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKD-------KPPPGAGARAAG 121
Cdd:PRK07003   361 AVTGGGAPGGGVParvagAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATraeappaAPAPPATADRGD 440
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  122 GAKAALGSRRAARVAPAEPLSRAGkPPGAEPPSAAAKgrKVKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCS 201
Cdd:PRK07003   441 DAADGDAPVPAKANARASADSRCD-ERDAQPPADSGS--ASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  202 RishtdssSDLSDCPSEPLSDEQRLLPAASSDAESGTG---------------SSDREPPRGAPTPSPAARGAPPGSPEP 266
Cdd:PRK07003   518 R-------EDAPAAAAPPAPEARPPTPAAAAPAARAGGaaaaldvlrnagmrvSSDRGARAAAAAKPAAAPAAAPKPAAP 590
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 2462559931  267 PALLAAPLaagacPGGRSIPSGVSGGFAGPGV-AEDVRGRSPPERPVP 313
Cdd:PRK07003   591 RVAVQVPT-----PRARAATGDAPPNGAARAEqAAESRGAPPPWEDIP 633
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
351-645 2.36e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.66  E-value: 2.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  351 KDELDELR---AEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLkv 427
Cdd:TIGR00606  244 ENELDPLKnrlKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKEREL-- 321
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  428 akdvsVRLHHELKtveekraKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNqqngGMERP 507
Cdd:TIGR00606  322 -----VDCQRELE-------KLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELD----GFERG 385
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  508 GNCRPATKTQRKLAPRRKDDSA--------DLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPT 579
Cdd:TIGR00606  386 PFSERQIKNFHTLVIERQEDEAktaaqlcaDLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQ 465
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462559931  580 GEaGGPPSTREAELKLR-----LKLVEEEANILGRKIVELEVEN------RGLKAEMEDMRgQQEREGPGRDHAPSI 645
Cdd:TIGR00606  466 LE-GSSDRILELDQELRkaereLSKAEKNSLTETLKKEVKSLQNekadldRKLRKLDQEME-QLNHHTTTRTQMEML 540
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
352-694 3.16e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.16  E-value: 3.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  352 DELDELRAEMEEmrdsyleedvyQLQELRRELDRANKNcRILQYRLRKAEQKSLKVAetgqvdgelIRSLEQDLKVAKDV 431
Cdd:COG1196    189 ERLEDILGELER-----------QLEPLERQAEKAERY-RELKEELKELEAELLLLK---------LRELEAELEELEAE 247
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  432 SVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQQNggMERpgncr 511
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER--LEE----- 320
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  512 pATKTQRKLAPRRKDDSAdlrcQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVDsplptgeaggppSTREA 591
Cdd:COG1196    321 -LEEELAELEEELEELEE----ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE------------EELEE 383
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  592 ELKLRLKLVEEEANILgRKIVELEVENRGLKAEMEDMRGQQEREGpgrdhapsiptspfGDSLESSTELRRHLQFVEEEA 671
Cdd:COG1196    384 LAEELLEALRAAAELA-AQLEELEEAEEALLERLERLEEELEELE--------------EALAELEEEEEEEEEALEEAA 448
                          330       340
                   ....*....|....*....|...
gi 2462559931  672 ELLRRSISEIEDHNRQLTHELSK 694
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEE 471
PHA03247 PHA03247
large tegument protein UL36; Provisional
6-264 3.21e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 3.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931    6 GPAGGGAPDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPFLKDLHARPAAPGP----AVPSSGRAPAPAAPRSPNLA 81
Cdd:PHA03247  2774 APAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPpptsAQPTAPPPPPGPPPPSLPLG 2853
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   82 GKAPP------------SPGSLAAPGR----------LSRRSGGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAE 139
Cdd:PHA03247  2854 GSVAPggdvrrrppsrsPAAKPAAPARppvrrlarpaVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  140 PLSRAGKPPGAEPPSAAAKGR-----------KVKRGSRAPPARTVGPPTPAARIPAVTlaVTSVAGSPArcSRISHTDS 208
Cdd:PHA03247  2934 PPPPRPQPPLAPTTDPAGAGEpsgavpqpwlgALVPGRVAVPRFRVPQPAPSREAPASS--TPPLTGHSL--SRVSSWAS 3009
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  209 SSDLS-DCPSEPLSDEQRLLPAASSDAESGTGSSDREPPR---GAPTPSPAARGAPPGSP 264
Cdd:PHA03247  3010 SLALHeETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERsdlEALDPLPPEPHDPFAHE 3069
PTZ00121 PTZ00121
MAEBL; Provisional
351-629 3.81e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.98  E-value: 3.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  351 KDELDELRaEMEEMRDSyleEDVYQLQELRRELDRANKNCRILQyRLRKAEQKslKVAETGQVDGELIRSLEQDLKVAKD 430
Cdd:PTZ00121  1545 KKKADELK-KAEELKKA---EEKKKAEEAKKAEEDKNMALRKAE-EAKKAEEA--RIEEVMKLYEEEKKMKAEEAKKAEE 1617
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  431 VSVRLhHELKTVEEKRAKAEDENETLRQQMIEVEISKQAlqNELERLKESSLKRRSTREMYKEKKTFNQQNGGMERPGNC 510
Cdd:PTZ00121  1618 AKIKA-EELKKAEEEKKKVEQLKKKEAEEKKKAEELKKA--EEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEAL 1694
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  511 RPATKTQRKLAPRRKDDSADLRCQLQFAKEEaflmRKKMAKLGREKDELEQELQKYKSLYGDvdsplpTGEaggppSTRE 590
Cdd:PTZ00121  1695 KKEAEEAKKAEELKKKEAEEKKKAEELKKAE----EENKIKAEEAKKEAEEDKKKAEEAKKD------EEE-----KKKI 1759
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462559931  591 AELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMR 629
Cdd:PTZ00121  1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
358-645 5.33e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.58  E-value: 5.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  358 RAEME-EMRDSYLEedvyqLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQvdgELIRSLeQDLKVAKDvsvRLH 436
Cdd:pfam15921  592 KAQLEkEINDRRLE-----LQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGS---ERLRAV-KDIKQERD---QLL 659
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  437 HELKTVEEKRAKAEDENETL----RQQMIEVEISKQALQNELerlkesslkRRSTREMYKEKKTFNQQNGGmerPGNC-R 511
Cdd:pfam15921  660 NEVKTSRNELNSLSEDYEVLkrnfRNKSEEMETTTNKLKMQL---------KSAQSELEQTRNTLKSMEGS---DGHAmK 727
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  512 PATKTQRKLAPRRKDDSAdLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVdsplptgeAGGPPSTREA 591
Cdd:pfam15921  728 VAMGMQKQITAKRGQIDA-LQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM--------AGELEVLRSQ 798
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462559931  592 ELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQ-------QEREGPGRDHAPSI 645
Cdd:pfam15921  799 ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKlqhtldvKELQGPGYTSNSSM 859
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
59-261 5.50e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 48.33  E-value: 5.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   59 PGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPgrlsrrsgGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPA 138
Cdd:PRK12323   365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPA--------APPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAA 436
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  139 EPLSRAGKPPGAEPPSAAAkgrkvkrgsrAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDSS--SDLSDCP 216
Cdd:PRK12323   437 RQASARGPGGAPAPAPAPA----------AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPpwEELPPEF 506
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462559931  217 SEPLSDEQRLLPA-ASSDAESGTGSSDREPPRGAPTPSPAARGAPP 261
Cdd:PRK12323   507 ASPAPAQPDAAPAgWVAESIPDPATADPDDAFETLAPAPAAAPAPR 552
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
41-297 5.54e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 48.63  E-value: 5.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   41 APSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPgsLAAPGRLSRRSGGVPGAKDKPPPGAGARAA 120
Cdd:PHA03307    48 AELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTL--APASPAREGSPTPPGPSSPDPPPPTPPPAS 125
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  121 GGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKVKRGSRAPPARTVGPPTPAARIPAVTLAV-TSVAGSPAR 199
Cdd:PHA03307   126 PPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPsTPPAAASPR 205
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  200 CSRISHTDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPA--------ARGAPPGSPEPPALLA 271
Cdd:PHA03307   206 PPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPApitlptriWEASGWNGPSSRPGPA 285
                          250       260
                   ....*....|....*....|....*.
gi 2462559931  272 APLAAGACPGGRSIPSGVSGGFAGPG 297
Cdd:PHA03307   286 SSSSSPRERSPSPSPSSPGSGPAPSS 311
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
354-585 6.04e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 6.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  354 LDELRAEMEEmrdsyLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGElIRSLEQDLKVAKDVSV 433
Cdd:COG4913    612 LAALEAELAE-----LEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAERE-IAELEAELERLDASSD 685
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  434 rlhhELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKEsslkrrstremykEKKTFNQQNGGMERPGNCRPA 513
Cdd:COG4913    686 ----DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEE-------------ELDELQDRLEAAEDLARLELR 748
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462559931  514 TKTQRKLA-----PRRKDDSADLRCQLQFAKeeaflmrkkmAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGP 585
Cdd:COG4913    749 ALLEERFAaalgdAVERELRENLEERIDALR----------ARLNRAEEELERAMRAFNREWPAETADLDADLESLP 815
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
375-565 6.27e-05

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 48.21  E-value: 6.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  375 QLQELRRELDRANKNcriLQYRLRKAEQKSLKVAETGQVD----GELIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAE 450
Cdd:pfam07111  482 ELEQLREERNRLDAE---LQLSAHLIQQEVGRAREQGEAErqqlSEVAQQLEQELQRAQESLASVGQQLEVARQGQQEST 558
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  451 DENETLRQQMI-EVEISKQALQN---ELE-RLKE--SSLKRR---STREMYKEKKTFNQqnggmerpgncrpatkTQRKl 520
Cdd:pfam07111  559 EEAASLRQELTqQQEIYGQALQEkvaEVEtRLREqlSDTKRRlneARREQAKAVVSLRQ----------------IQHR- 621
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462559931  521 APRRKDDSADL-RCQLQFAKEEAFLMRKKMAKLGREKDELEQELQK 565
Cdd:pfam07111  622 ATQEKERNQELrRLQDEARKEEGQRLARRVQELERDKNLMLATLQQ 667
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
86-218 1.09e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 47.37  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   86 PSPGSLAAPGRLSRRSGGVPGAKDKPPPGagaraaggakaalgSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGRKVKRG 165
Cdd:PRK14959   373 PSGGGASAPSGSAAEGPASGGAATIPTPG--------------TQGPQGTAPAAGMTPSSAAPATPAPSAAPSPRVPWDD 438
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462559931  166 SRAPPARTVGPPTPAARIPavtlAVTSVAGSPARCSRISHTDSSSDLSDCPSE 218
Cdd:PRK14959   439 APPAPPRSGIPPRPAPRMP----EASPVPGAPDSVASASDAPPTLGDPSDTAE 487
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
350-494 1.44e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 1.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDG---ElIRSLEQDLK 426
Cdd:COG1579     29 LPAELAELEDELAALEARLEAAKT-ELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEAlqkE-IESLKRRIS 106
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462559931  427 VAKDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVeisKQALQNELERLKESSLKRRSTREMYKEK 494
Cdd:COG1579    107 DLEDEILELMERIEELEEELAELEAELAELEAELEEK---KAELDEELAELEAELEELEAEREELAAK 171
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
352-617 1.45e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  352 DELDELRAEMEEMRDsyleedvyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETgqvdgelIRSLEQDLKVAKDv 431
Cdd:COG4942     20 DAAAEAEAELEQLQQ--------EIAELEKELAALKKEEKALLKQLAALERRIAALARR-------IRALEQELAALEA- 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  432 svrlhhELKTVEEKRAKAEDENETLRQQMIEV--EISKQALQNELERLkessLKRRSTREMYKEKKTFNQQNggmerpgn 509
Cdd:COG4942     84 ------ELAELEKEIAELRAELEAQKEELAELlrALYRLGRQPPLALL----LSPEDFLDAVRRLQYLKYLA-------- 145
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  510 crPATKTQRKLAPRRKDDSADLRCQLQFAKEEaflMRKKMAKLGREKDELEQELQKYKSLYGDVdsplptgeaggppSTR 589
Cdd:COG4942    146 --PARREQAEELRADLAELAALRAELEAERAE---LEALLAELEEERAALEALKAERQKLLARL-------------EKE 207
                          250       260
                   ....*....|....*....|....*...
gi 2462559931  590 EAELKLRLKLVEEEANILGRKIVELEVE 617
Cdd:COG4942    208 LAELAAELAELQQEAEELEALIARLEAE 235
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
350-635 1.96e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 1.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQK------SLKVAETGQVDGELIRSLEQ 423
Cdd:COG4717    168 LEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEleeleeELEQLENELEAAALEERLKE 247
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  424 DLKVAKDVSVRLHHE----------------------------LKTVEEKRAKAEDENETLRQQMIEvEISKQALQNELE 475
Cdd:COG4717    248 ARLLLLIAAALLALLglggsllsliltiagvlflvlgllallfLLLAREKASLGKEAEELQALPALE-ELEEEELEELLA 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  476 RLK-ESSLKRRSTREMYKEKKTFNQQNGGMERpgncrpaTKTQRKLAPRRKDDSADLRcQLQFAKEEAFLMRkkmAKLGR 554
Cdd:COG4717    327 ALGlPPDLSPEELLELLDRIEELQELLREAEE-------LEEELQLEELEQEIAALLA-EAGVEDEEELRAA---LEQAE 395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  555 EKDELEQELQKYKSLYGDVDSPLPTGEAGGPPST---REAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQ 631
Cdd:COG4717    396 EYQELKEELEELEEQLEELLGELEELLEALDEEEleeELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELL 475

                   ....
gi 2462559931  632 QERE 635
Cdd:COG4717    476 QELE 479
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
144-264 1.99e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 46.25  E-value: 1.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  144 AGKPPGAEPPSAAAKGRKVKRGSRAPPARTVGPPTPAARIPAVTL-AVTSVAGSPArcSRISHTDSSSDLSDCPSEPLSD 222
Cdd:PRK14951   363 AFKPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPaAAASAPAAPP--AAAPPAPVAAPAAAAPAAAPAA 440
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 2462559931  223 EQRLLPAASSDAESGTGSSDREPPRGAPTPSPA-ARGAPPGSP 264
Cdd:PRK14951   441 APAAVALAPAPPAQAAPETVAIPVRVAPEPAVAsAAPAPAAAP 483
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
350-479 2.20e-04

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 46.00  E-value: 2.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDSYL--EEDVYQLQELRRELDRANKNCRILQYRLRKAEQ-------------KSLKVAETGQVD 414
Cdd:pfam06160  303 AEEQNKELKEELERVQQSYTlnENELERVRGLEKQLEELEKRYDEIVERLEEKEVayselqeeleeilEQLEEIEEEQEE 382
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  415 G-ELIRSLEQDLKVAKDVSVRLHHELKTVE---EKR-------------AKAEDENETLRQQMIEV-----EISKQAL-- 470
Cdd:pfam06160  383 FkESLQSLRKDELEAREKLDEFKLELREIKrlvEKSnlpglpesyldyfFDVSDEIEDLADELNEVplnmdEVNRLLDea 462

                   ....*....
gi 2462559931  471 QNELERLKE 479
Cdd:pfam06160  463 QDDVDTLYE 471
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
13-319 2.27e-04

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 46.21  E-value: 2.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   13 PDAKLQPPGQHHRHHHLHPVAERrrLHRAPSPARPFLKDLHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLA 92
Cdd:COG5180    158 SDPILAKDPDGDSASTLPPPAEK--LDKVLTEPRDALKDSPEKLDRPKVEVKDEAQEEPPDLTGGADHPRPEAASSPKVD 235
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   93 APGRLSRRSGgvPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAA-AKGRKVKRGSRAPPA 171
Cdd:COG5180    236 PPSTSEARSR--PATVDAQPEMRPPADAKERRRAAIGDTPAAEPPGLPVLEAGSEPQSDAPEAEtARPIDVKGVASAPPA 313
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  172 RTVGPPTPAAR---IPAVTLAVTSVAGSPARCSRISHTDSSSDlsdcPSEPLSDEQRLLPAASSDAESGTGSSDREPPRG 248
Cdd:COG5180    314 TRPVRPPGGARdpgTPRPGQPTERPAGVPEAASDAGQPPSAYP----PAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNG 389
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462559931  249 APTPSPaARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAedvrgRSPPERPVPGTPKEP 319
Cdd:COG5180    390 APQPGL-GRRGAPGPPMGAGDLVQAALDGGGRETASLGGAAGGAGQGPKAD-----FVPGDAESVSGPAGL 454
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
350-499 3.24e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 3.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVA- 428
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAe 434
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462559931  429 -KDVSVRLHHELKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQ 499
Cdd:TIGR02168  435 lKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSE 506
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
82-326 4.18e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.55  E-value: 4.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   82 GKAPPSPGSLAAPGRLSRRSGGvPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAG-------KPPGAEPPS 154
Cdd:PHA03307    69 TGPPPGPGTEAPANESRSTPTW-SLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPApdlsemlRPVGSPGPP 147
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  155 AAAKGRKVKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAG----SPARCSRISHTDSSSDLSDcPSEPLSDEQRLLPAA 230
Cdd:PHA03307   148 PAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSppaePPPSTPPAAASPRPPRRSS-PISASASSPAPAPGR 226
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  231 SSDAESGTGSSDREPPRGAPTPSpAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPgvaedvRGRSPPer 310
Cdd:PHA03307   227 SAADDAGASSSDSSSSESSGCGW-GPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSP------RERSPS-- 297
                          250
                   ....*....|....*.
gi 2462559931  311 PVPGTPKEPSLGEQSR 326
Cdd:PHA03307   298 PSPSSPGSGPAPSSPR 313
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
338-694 4.70e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 45.35  E-value: 4.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  338 REMEELRSENDYLKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRankncRILQYRLRKAEQKSLKvaetgqVDGEL 417
Cdd:pfam02463  177 KLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-----YLLYLDYLKLNEERID------LLQEL 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  418 IRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDEnetlrQQMIEVEISKQALQNELERLKESSLKRRSTREmyKEKKTF 497
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE-----KKLQEEELKLLAKEEEELKSELLKLERRKVDD--EEKLKE 318
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  498 NQQNggmerpgncrpATKTQRKLAPRRKDdsadlrcQLQFAKEEAFLMRKKmAKLGREKDELEQELQKYKSLYGDVDSPL 577
Cdd:pfam02463  319 SEKE-----------KKKAEKELKKEKEE-------IEELEKELKELEIKR-EAEEEEEEELEKLQEKLEQLEEELLAKK 379
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  578 PTGEAGGPPSTREAELKLRLKLVEEeaNILGRKIVELEVENRGLKAEMEDMRGQQEREGpgrdhapsiptsPFGDSLESS 657
Cdd:pfam02463  380 KLESERLSSAAKLKEEELELKSEEE--KEAQLLLELARQLEDLLKEEKKEELEILEEEE------------ESIELKQGK 445
                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 2462559931  658 TELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSK 694
Cdd:pfam02463  446 LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKL 482
PTZ00121 PTZ00121
MAEBL; Provisional
352-496 5.03e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 5.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  352 DELDELRAEMEEMRDsylEEDVYQLQELRRELDRANKNCRILQyrlRKAEQKSlKVAETGQVDGELIRSLEQDLKVAKDV 431
Cdd:PTZ00121  1656 EEENKIKAAEEAKKA---EEDKKKAEEAKKAEEDEKKAAEALK---KEAEEAK-KAEELKKKEAEEKKKAEELKKAEEEN 1728
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462559931  432 SVRLHHELKTVEEKRAKAE----DENETLRQQMIEVEISKQALQNELER---LKESSLKRRSTREMYKEKKT 496
Cdd:PTZ00121  1729 KIKAEEAKKEAEEDKKKAEeakkDEEEKKKIAHLKKEEEKKAEEIRKEKeavIEEELDEEDEKRRMEVDKKI 1800
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
346-500 5.25e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 5.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  346 ENDYLKDELDELRAE--MEEMRDSYLEEDVYQLQELRRELDRANKN--CRILQYRLRKAEQKSLKVAETgQVDGELIRSL 421
Cdd:pfam17380  390 KNERVRQELEAARKVkiLEEERQRKIQQQKVEMEQIRAEQEEARQRevRRLEEERAREMERVRLEEQER-QQQVERLRQQ 468
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  422 EQDLKVAKDVSVRLHHELKTVEEKRAKA-EDENETLRQQMIEVEISKQALQNELE----------RLKESSLKRRSTREM 490
Cdd:pfam17380  469 EEERKRKKLELEKEKRDRKRAEEQRRKIlEKELEERKQAMIEEERKRKLLEKEMEerqkaiyeeeRRREAEEERRKQQEM 548
                          170
                   ....*....|
gi 2462559931  491 yKEKKTFNQQ 500
Cdd:pfam17380  549 -EERRRIQEQ 557
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
345-569 5.98e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 44.13  E-value: 5.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  345 SENDYLKDELDELRAEMEEMRDSYLE---------EDVYQLQELRRELDRANKNCRILQYRLRKAEQKSlkvaETGQVDG 415
Cdd:COG1340     57 EEAQELREKRDELNEKVKELKEERDElneklnelrEELDELRKELAELNKAGGSIDKLRKEIERLEWRQ----QTEVLSP 132
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  416 EL-------IRSLEQDLKVAKDvSVRLHHELKTVEEKRAKAEDENETLRQQMieveiskQALQNELERLKESSLKRRSTR 488
Cdd:COG1340    133 EEekelvekIKELEKELEKAKK-ALEKNEKLKELRAELKELRKEAEEIHKKI-------KELAEEAQELHEEMIELYKEA 204
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  489 -EMYKEKKTFNQQNggmerpGNCRPATKTQRKLAPRRKDDSADLRCQL--QFAKEEAFLMRKKMAKLGREKDELEQELQK 565
Cdd:COG1340    205 dELRKEADELHKEI------VEAQEKADELHEEIIELQKELRELRKELkkLRKKQRALKREKEKEELEEKAEEIFEKLKK 278

                   ....
gi 2462559931  566 YKSL 569
Cdd:COG1340    279 GEKL 282
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
102-323 6.19e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.98  E-value: 6.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  102 GGVPGAKDKPPPGAGARAAGGAKAalgSRRAARVAPAEPlSRAGKPPGAEPPSAAAkgrkvkrgsrAPPARTVGPPTPAA 181
Cdd:PRK07764   589 GPAPGAAGGEGPPAPASSGPPEEA---ARPAAPAAPAAP-AAPAPAGAAAAPAEAS----------AAPAPGVAAPEHHP 654
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  182 RIPAVTLAVTSVAGSPArcsrishtDSSSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPP 261
Cdd:PRK07764   655 KHVAVPDASDGGDGWPA--------KAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQ 726
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462559931  262 GSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGE 323
Cdd:PRK07764   727 GASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAED 788
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
12-265 6.45e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.98  E-value: 6.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   12 APDAKLQPPGQHHRHHHLHPVAERRRLHRAPSPARPflkdlhARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSL 91
Cdd:PRK07764   583 QVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAP------AAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKH 656
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   92 AAPGRLSRRSGGVPGAKDKPPPGAGARAaggakaalgSRRAARVAPAEPlsrAGKPPGAEPPSAAAKGRkvkrgSRAPPA 171
Cdd:PRK07764   657 VAVPDASDGGDGWPAKAGGAAPAAPPPA---------PAPAAPAAPAGA---APAQPAPAPAATPPAGQ-----ADDPAA 719
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  172 RTVGPPTPAARIPAVTLAVTSVAGSParcsrishtdsssDLSDCPSEPLSDEQrllPAASSDAESGTGSSDREPPRGAPT 251
Cdd:PRK07764   720 QPPQAAQGASAPSPAADDPVPLPPEP-------------DDPPDPAGAPAQPP---PPPAPAPAAAPAAAPPPSPPSEEE 783
                          250
                   ....*....|....
gi 2462559931  252 PSPAARGAPPGSPE 265
Cdd:PRK07764   784 EMAEDDAPSMDDED 797
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
349-570 8.44e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 8.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  349 YLKDELDELRAEMEEMRDsYLEEdvyQLQELRRELDRANKncRILQYRlrkAEQKSLKVAETGQVDGELIRSLEQDLKVA 428
Cdd:COG3206    161 YLEQNLELRREEARKALE-FLEE---QLPELRKELEEAEA--ALEEFR---QKNGLVDLSEEAKLLLQQLSELESQLAEA 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  429 KDVSVRLHHELKTVEEKRAKAEDEN---------ETLRQQMIEVEiskQALQNELERLKESSLKRRSTREMYKEKKTFNQ 499
Cdd:COG3206    232 RAELAEAEARLAALRAQLGSGPDALpellqspviQQLRAQLAELE---AELAELSARYTPNHPDVIALRAQIAALRAQLQ 308
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462559931  500 QnggmeRPGNCRPATKTQRKLAPRRKddsADLRCQLQFAKEEAflmrKKMAKLGREKDELEQELQKYKSLY 570
Cdd:COG3206    309 Q-----EAQRILASLEAELEALQARE---ASLQAQLAQLEARL----AELPELEAELRRLEREVEVARELY 367
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
345-683 8.44e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.40  E-value: 8.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  345 SENDYLKDELDEL-RAEME-EMRDSYLEEdvyQLQELRRELDRANKNCRILQYRLRKAEqkslkvAETGQVDGELIRSLE 422
Cdd:pfam01576  384 SENAELQAELRTLqQAKQDsEHKRKKLEG---QLQELQARLSESERQRAELAEKLSKLQ------SELESVSSLLNEAEG 454
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  423 QDLKVAKDVSvRLHHELKTV-----EEKRAK---------AEDENETLRQQMIEVEISKQALQNELERLKE--SSLKRR- 485
Cdd:pfam01576  455 KNIKLSKDVS-SLESQLQDTqellqEETRQKlnlstrlrqLEDERNSLQEQLEEEEEAKRNVERQLSTLQAqlSDMKKKl 533
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  486 ------------STREMYKEKKTFNQQNGgmERPGNCRPATKTQRKLAPRRKDDSADLRCQLQFA-----KEEAF---LM 545
Cdd:pfam01576  534 eedagtlealeeGKKRLQRELEALTQQLE--EKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVsnlekKQKKFdqmLA 611
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  546 RKKM--AKLGREKDELEQElqkykslygdvdsplptgeaggppsTREAELK-LRLKLVEEEANilgRKIVELEVENRGLK 622
Cdd:pfam01576  612 EEKAisARYAEERDRAEAE-------------------------AREKETRaLSLARALEEAL---EAKEELERTNKQLR 663
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462559931  623 AEMEDMRGQQEREGpgrdhapsiptspfgdslESSTELRRHLQFVEEEAELLRRSISEIED 683
Cdd:pfam01576  664 AEMEDLVSSKDDVG------------------KNVHELERSKRALEQQVEEMKTQLEELED 706
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
149-314 9.28e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.10  E-value: 9.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  149 GAEPPSAAAKGRKVKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRishtdsssdlsdcpseplsdeqRLLP 228
Cdd:PRK12323   371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPA----------------------RRSP 428
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  229 AASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSGVSGGFAGPGVAEDVrgrsPP 308
Cdd:PRK12323   429 APEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEEL----PP 504

                   ....*.
gi 2462559931  309 ERPVPG 314
Cdd:PRK12323   505 EFASPA 510
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
130-313 1.13e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  130 RRAARVAPAEPLSRA-GKPPGAEPPSAAAKGRKVKRGSRAPPARTVGPPTPAARIPAVTLAVTSVAGSPARCSRISHTDS 208
Cdd:PHA03307   742 RRARARASAWDITDAlFSNPSLVPAKLAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRKS 821
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  209 SSDLSDCPSEPLSDEQRLLPAASSDAESGTGSSDREPPRGAPTPSPAARGAPPGSPEPPALLAAPLAAGACPGGRSIPSG 288
Cdd:PHA03307   822 RSHTPDGGSESSGPARPPGAAARPPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAP 901
                          170       180
                   ....*....|....*....|....*
gi 2462559931  289 VSggfAGPGVAEDVRGRSPPERPVP 313
Cdd:PHA03307   902 AP---RPRPAPRVKLGPMPPGGPDP 923
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
345-634 1.15e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 43.96  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  345 SENDYLKDELDELRAEMEEMRDSYLEEDVYQLQE---LRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSL 421
Cdd:pfam05557    2 AELIESKARLSQLQNEKKQMELEHKRARIELEKKasaLKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLK 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  422 EQDL---------KVAKDVSVR-LHHELKT-VEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREM 490
Cdd:pfam05557   82 KKYLealnkklneKESQLADAReVISCLKNeLSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQ 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  491 YKEKKTFNQQNGGMER-------------PGNCRPAT--KTQRKLAPRR----------------KDDSADLRCQLQfaK 539
Cdd:pfam05557  162 QSSLAEAEQRIKELEFeiqsqeqdseivkNSKSELARipELEKELERLRehnkhlnenienklllKEEVEDLKRKLE--R 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  540 EEAflMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPP----STREAELKLRLKLVEEEANILGRKIVELE 615
Cdd:pfam05557  240 EEK--YREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRieqlQQREIVLKEENSSLTSSARQLEKARRELE 317
                          330
                   ....*....|....*....
gi 2462559931  616 VENRGLKAEMEDMRGQQER 634
Cdd:pfam05557  318 QELAQYLKKIEDLNKKLKR 336
DUF4201 pfam13870
Domain of unknown function (DUF4201); This is a family of coiled-coil proteins from eukaryotes. ...
376-507 1.19e-03

Domain of unknown function (DUF4201); This is a family of coiled-coil proteins from eukaryotes. The function is not known.


Pssm-ID: 464008 [Multi-domain]  Cd Length: 177  Bit Score: 41.82  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  376 LQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQ----VD-----------GELIRSLEQDLKVAKDVSVRLHHELK 440
Cdd:pfam13870    1 MRAKRNELSKLRLELITLKHTLAKIQEKLEQKEELGEgltmIDflqlqienqalNEKIEERNKELKRLKLKVTNTVHALT 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462559931  441 TVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRstremyKEKKTFNQQNGGMERP 507
Cdd:pfam13870   81 HLKEKLHFLSAELSRLKKELRERQELLAKLRKELYRVKLERDKLR------KQNKKLRQQGGLLHVP 141
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
362-697 1.40e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 1.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  362 EEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVD--GELIRSLEQDLKVakdvsvrlhHEL 439
Cdd:PRK03918   447 EEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKelAEQLKELEEKLKK---------YNL 517
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  440 KTVEEKrakaEDENETLRQQMIEVEISKQALQNELERLKEssLKRRST------REMYKEKKTFNQQNGGM--------- 504
Cdd:PRK03918   518 EELEKK----AEEYEKLKEKLIKLKGEIKSLKKELEKLEE--LKKKLAelekklDELEEELAELLKELEELgfesveele 591
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  505 ERPGNCRPATKTQRKLAPRRKDDSADLRcQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDvdsplptgEAGG 584
Cdd:PRK03918   592 ERLKELEPFYNEYLELKDAEKELEREEK-ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--------EEYE 662
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  585 PPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERegpgrdhapsipTSPFGDSLESSTELRRhl 664
Cdd:PRK03918   663 ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE------------LEKLEKALERVEELRE-- 728
                          330       340       350
                   ....*....|....*....|....*....|...
gi 2462559931  665 QFVEEEAELLRRSISEIEDHNRQLTHELSKFKF 697
Cdd:PRK03918   729 KVKKYKALLKERALSKVGEIASEIFEELTEGKY 761
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
110-262 1.46e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.55  E-value: 1.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  110 KPPPGAGaraaggakaalgsrrAARVAPAEPLSRAGKP-PGAEPPSAAAKGRKVKrgsRAPPARTVGPPTPAARI-PAVT 187
Cdd:PRK14951   365 KPAAAAE---------------AAAPAEKKTPARPEAAaPAAAPVAQAAAAPAPA---AAPAAAASAPAAPPAAApPAPV 426
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462559931  188 LAVTSVAGSPARcsriSHTDSSSDLSDCPSEPLSDEQRLLPAAssdAESGTGSSDREPPRGAPTPSPAARGAPPG 262
Cdd:PRK14951   427 AAPAAAAPAAAP----AAAPAAVALAPAPPAQAAPETVAIPVR---VAPEPAVASAAPAPAAAPAAARLTPTEEG 494
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
391-493 1.74e-03

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 41.56  E-value: 1.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  391 RILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDL-----KVAKDVSVRLHHELKTVEEKRAKAED---ENETLRQQMIE 462
Cdd:pfam15035   24 KVLQYKKRCSELEQQLLEKTSELEKTELLLRKLTLeprlqRLEREHSADLEEALIRLEEERQRSESlsqVNSLLREQLEQ 103
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2462559931  463 VEISKQALQNELERL-------------KESSLKRRstREMYKE 493
Cdd:pfam15035  104 ASRANEALREDLQKLtndwerareeleqKESEWRKE--EEAFNE 145
PRK01156 PRK01156
chromosome segregation protein; Provisional
348-740 1.90e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.35  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  348 DYLKDELDELRAEMEEMrdSYLEEDVY----QLQELRRELDRANKNCRILqyrLRKAEQKSlkvAETGQVDGELI--RSL 421
Cdd:PRK01156   169 DKLKDVIDMLRAEISNI--DYLEEKLKssnlELENIKKQIADDEKSHSIT---LKEIERLS---IEYNNAMDDYNnlKSA 240
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  422 EQDLKVAKDVSVRLHHELKTVEEKRAKAEDENetlrqqmieVEISkqALQNELERLKESSL--KRRSTREMYKEKKTFNQ 499
Cdd:PRK01156   241 LNELSSLEDMKNRYESEIKTAESDLSMELEKN---------NYYK--ELEERHMKIINDPVykNRNYINDYFKYKNDIEN 309
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  500 QNGGMER-PGNCRPATKTQRKLAPRRKDDSadlrcqlQFAKeeaflMRKKMAKLGREKDELEQELQKYKSLYGDVDS--- 575
Cdd:PRK01156   310 KKQILSNiDAEINKYHAIIKKLSVLQKDYN-------DYIK-----KKSRYDDLNNQILELEGYEMDYNSYLKSIESlkk 377
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  576 ------------PLPTGEAGGPPSTREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQEREGpGRDHAP 643
Cdd:PRK01156   378 kieeyskniermSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLN-GQSVCP 456
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  644 SIPTSpFGDslESSTELRRH----LQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPPREpgwlgegASPGAGGGAP 719
Cdd:PRK01156   457 VCGTT-LGE--EKSNHIINHynekKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINK-------SINEYNKIES 526
                          410       420
                   ....*....|....*....|.
gi 2462559931  720 LQEELKSARLQISELSGKVLK 740
Cdd:PRK01156   527 ARADLEDIKIKINELKDKHDK 547
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
416-696 2.66e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  416 ELIRSLEQDLKVAKDVSVRLhhelKTVEEKRAKAEDENETLRQQMIEVEISKQALQNELERLKESslkRRSTREMYKEKK 495
Cdd:PRK03918   176 RRIERLEKFIKRTENIEELI----KEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL---KEEIEELEKELE 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  496 TFNQQNGGME-RPGNCRPATKTQRKLAPRRKDDSADLRcQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYKSLYGDVD 574
Cdd:PRK03918   249 SLEGSKRKLEeKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIE 327
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  575 SPLPTGEAggpPSTREAELKLRLKLVEEEANILGRKIVELEVenrgLKAEMEDMRGQQEREGPgrdhapsiptspfgdsl 654
Cdd:PRK03918   328 ERIKELEE---KEERLEELKKKLKELEKRLEELEERHELYEE----AKAKKEELERLKKRLTG----------------- 383
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2462559931  655 ESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFK 696
Cdd:PRK03918   384 LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELK 425
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
350-487 2.70e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDSYLEEDVyQLQELRRELDRANKncrilqyRLRKAEQKSLKVAETgqvDGELIRSLEQDLKvak 429
Cdd:COG3206    268 LRAQLAELEAELAELSARYTPNHP-DVIALRAQIAALRA-------QLQQEAQRILASLEA---ELEALQAREASLQ--- 333
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462559931  430 dvsvrlhhelKTVEEKRAKAEDENETLRQQMI---EVEISKQALQNELERLKESSLKRRST 487
Cdd:COG3206    334 ----------AQLAQLEARLAELPELEAELRRlerEVEVARELYESLLQRLEEARLAEALT 384
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
340-633 2.74e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  340 MEELRSENDYLKDELDELRAEMEEMRDSYLEEDVYQLQELRRELDRANKNCRILQYRLRKAEQKsLKVAETGQVDGELIR 419
Cdd:COG4717    165 LEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE-LEQLENELEAAALEE 243
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  420 SLEQDLKVAKDVSVRLHHE----------------------------LKTVEEKRAKAEDENETLRQQMIEvEISKQALQ 471
Cdd:COG4717    244 RLKEARLLLLIAAALLALLglggsllsliltiagvlflvlgllallfLLLAREKASLGKEAEELQALPALE-ELEEEELE 322
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  472 NELERLK-ESSLKRRSTREMYKEKKTFNQQNGGMERpgncrpaTKTQRKLAPRRKDDSADLRcQLQFAKEEAFLMRkkmA 550
Cdd:COG4717    323 ELLAALGlPPDLSPEELLELLDRIEELQELLREAEE-------LEEELQLEELEQEIAALLA-EAGVEDEEELRAA---L 391
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  551 KLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPpstrEAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRG 630
Cdd:COG4717    392 EQAEEYQELKEELEELEEQLEELLGELEELLEALD----EEELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467

                   ...
gi 2462559931  631 QQE 633
Cdd:COG4717    468 DGE 470
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
31-156 2.78e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.78  E-value: 2.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   31 PVAERRRLHRaPSPARPFLKDLHARPAAPGPAVPSSGrapapaaprspnlAGKAPPSPGSLAAPGRLSRRSGGVPGAKDK 110
Cdd:PRK14951   374 APAEKKTPAR-PEAAAPAAAPVAQAAAAPAPAAAPAA-------------AASAPAAPPAAAPPAPVAAPAAAAPAAAPA 439
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2462559931  111 PPPGAGARAAGGAKAALGSRRA--ARVAPAEPLSRAGKPPGAEPPSAA 156
Cdd:PRK14951   440 AAPAAVALAPAPPAQAAPETVAipVRVAPEPAVASAAPAPAAAPAAAR 487
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
40-331 3.66e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 3.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   40 RAPSPARPflkdlHARPAAPGPAVPSSGRAPAPAAPRSPNLAGKAPPSPGSLAAPGRLSRRSGGVPGAKDKPPPGAGARA 119
Cdd:PRK07764   392 GAPAAAAP-----SAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQP 466
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  120 AGGAKAALGSRRAARVAPAEPLSRAGKPPGAEPPSAAAKGR--------------KVKRGSRAPPARTVGPPTPAA-RIP 184
Cdd:PRK07764   467 APAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADdaatlrerwpeilaAVPKRSRKTWAILLPEATVLGvRGD 546
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  185 AVTLAVTSvAGSPARCSRISHTDSSSDL------SDC-------PSEPLSDEQRllPAASSDAESGTGSSDREPPRGAPT 251
Cdd:PRK07764   547 TLVLGFST-GGLARRFASPGNAEVLVTAlaeelgGDWqveavvgPAPGAAGGEG--PPAPASSGPPEEAARPAAPAAPAA 623
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  252 PSPAARGAPPGSPEPPALLAAPLA--AGACPGGRSIPSGVSGGFAGPGVAEDVRGRSPPERPVPGTPKEPSLGEQSRLVP 329
Cdd:PRK07764   624 PAAPAPAGAAAAPAEASAAPAPGVaaPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAP 703

                   ..
gi 2462559931  330 AA 331
Cdd:PRK07764   704 AP 705
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1197-1372 3.71e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931 1197 KQVVENQQ-LFSAFKALLEDFRAELREDERARLRLQ---QQYASDKAAWDVEWAVLKCRLEQLEEKTENKLGELGSSAES 1272
Cdd:TIGR02168  788 EAQIEQLKeELKALREALDELRAELTLLNEEAANLRerlESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931 1273 KGALKKEREVHQKLLADSHSLVMDLRWQIH---HSEKNWNREKVELLDRLDRDRQEWER-------------QKKEFLWr 1336
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEelsEELRELESKRSELRRELEELREKLAQlelrleglevridNLQERLS- 946
                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 2462559931 1337 iEQGSLRMPRPVAMWPCADADSIPFEDRpLSKLKES 1372
Cdd:TIGR02168  947 -EEYSLTLEEAEALENKIEDDEEEARRR-LKRLENK 980
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
526-754 4.32e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  526 DDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYkslygdvdsplptgeaggppSTREAELKLRLKLVEEEAN 605
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL--------------------ERRIAALARRIRALEQELA 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  606 ILGRKIVELEVENRGLKAEMEDMRGQQER-----EGPGRDHAPSIPTSP--FGDSLESSTELRRHLQFVEEEAELLRRSI 678
Cdd:COG4942     80 ALEAELAELEKEIAELRAELEAQKEELAEllralYRLGRQPPLALLLSPedFLDAVRRLQYLKYLAPARREQAEELRADL 159
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462559931  679 SEIEDHNRQLTHELSKfkfepprepgwLGEGASPGAGGGAPLQEELKSARLQISELSGKVLKLQHENHALLSNIQR 754
Cdd:COG4942    160 AELAALRAELEAERAE-----------LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
374-489 4.33e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  374 YQLQELRRELDRANKNCRILQYRLRKAEQKslkvaetgqvdgelIRSLEQDLKVAKDVSVRLHHELKTVEEKRAKAEDEN 453
Cdd:COG1579     10 LDLQELDSELDRLEHRLKELPAELAELEDE--------------LAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI 75
                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 2462559931  454 ETLRQQMIEVEISK--QALQNELERLKesslKRRSTRE 489
Cdd:COG1579     76 KKYEEQLGNVRNNKeyEALQKEIESLK----RRISDLE 109
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
356-688 4.81e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 42.05  E-value: 4.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  356 ELRAEMEEMRDSyLEEDVYQLQELRRELDRANKNCRILQYRLRKaeqkslKVAETgQVDGELIRSLEQDLKVAKDVSVRL 435
Cdd:pfam07111  321 QLKAQDLEHRDS-VKQLRGQVAELQEQVTSQSQEQAILQRALQD------KAAEV-EVERMSAKGLQMELSRAQEARRRQ 392
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  436 HHELKTVEEKR----AKAEDENETLRQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQQNGGMERPGNCR 511
Cdd:pfam07111  393 QQQTASAEEQLkfvvNAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLRQESCPPPPPA 472
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  512 PATKTQRKLAPRR-KDDSADLRCQLQF-----------AKEEAFLMRKKMAKLGREkdeLEQELQKYKSLYGDVDSPLPT 579
Cdd:pfam07111  473 PPVDADLSLELEQlREERNRLDAELQLsahliqqevgrAREQGEAERQQLSEVAQQ---LEQELQRAQESLASVGQQLEV 549
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  580 GEAGGPPSTREAElKLRLKLVEEEaNILGRKIVE--LEVENRgLKAEMEDM--RGQQERegpgRDHAPSIPT-----SPF 650
Cdd:pfam07111  550 ARQGQQESTEEAA-SLRQELTQQQ-EIYGQALQEkvAEVETR-LREQLSDTkrRLNEAR----REQAKAVVSlrqiqHRA 622
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 2462559931  651 GDSLESSTELRR-HLQFVEEEAELLRRSISEIE-DHNRQL 688
Cdd:pfam07111  623 TQEKERNQELRRlQDEARKEEGQRLARRVQELErDKNLML 662
PHA03247 PHA03247
large tegument protein UL36; Provisional
7-311 6.26e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 6.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931    7 PAGGGAPD------AKLQPPGQHHRHHHLHPVAERRRLHRAPsparpflkdLHARPAAPGPAVPSSGRAPAPAAPRSPNL 80
Cdd:PHA03247   206 PSGPGPAApadltaAALHLYGASETYLQDEPFVERRVVISHP---------LRGDIAAPAPPPVVGEGADRAPETARGAT 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   81 AGKAPPSPGSLAAPGRLSRRS-----GGVPGAKDKPPPGAGARAAGGAKAALGSRRAARVAPAEPLSRAGKP-------- 147
Cdd:PHA03247   277 GPPPPPEAAAPNGAAAPPDGVwgaalAGAPLALPAPPDPPPPAPAGDAEEEDDEDGAMEVVSPLPRPRQHYPlgfpkrrr 356
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  148 PGAEPPSAA---AKGRKVKRgsRAPPARTVGPPTPAARIPavtlavtsVAGSPArcsrishtdssSDLSDCPSEPlsdeq 224
Cdd:PHA03247   357 PTWTPPSSLedlSAGRHHPK--RASLPTRKRRSARHAATP--------FARGPG-----------GDDQTRPAAP----- 410
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  225 rlLPAASSDAESGTGSSDREPPRGAPTPSP-AARGAPPGSPeppallaaplAAGACPGGRSIPSGVSGGFAGPGVAEDVR 303
Cdd:PHA03247   411 --VPASVPTPAPTPVPASAPPPPATPLPSAePGSDDGPAPP----------PERQPPAPATEPAPDDPDDATRKALDALR 478

                   ....*...
gi 2462559931  304 GRSPPERP 311
Cdd:PHA03247   479 ERRPPEPP 486
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
392-624 6.80e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 6.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  392 ILQYRLRKAEQKSLKV-AETGQVDGELIRSLEQDLKvakdvsvrlhhELKTVEEKRAKAEDENETLRQQMIEVEISKQAL 470
Cdd:COG4717     46 MLLERLEKEADELFKPqGRKPELNLKELKELEEELK-----------EAEEKEEEYAELQEELEELEEELEELEAELEEL 114
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  471 QNELERLKesslKRRSTREMYKEKKTFNQQ-NGGMERpgncrpATKTQRKLAPRRkddsaDLRCQLQFAKEEAFLMRKKM 549
Cdd:COG4717    115 REELEKLE----KLLQLLPLYQELEALEAElAELPER------LEELEERLEELR-----ELEEELEELEAELAELQEEL 179
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462559931  550 AKLGREKD-ELEQELQKYKSLYGDVDSplptgeaggppstREAELKLRLKLVEEEANILGRKIVELEVENRGLKAE 624
Cdd:COG4717    180 EELLEQLSlATEEELQDLAEELEELQQ-------------RLAELEEELEEAQEELEELEEELEQLENELEAAALE 242
PHA03378 PHA03378
EBNA-3B; Provisional
36-184 6.87e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 41.59  E-value: 6.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931   36 RRLHRAPSPARPflkdlhaRPAAPGPAVPSSGRAPAPAAPrspnlAGKAPPSPGSLAAPGRLsRRSGGVPGAKdkPPPGA 115
Cdd:PHA03378   685 LPIQWAPGTMQP-------PPRAPTPMRPPAAPPGRAQRP-----AAATGRARPPAAAPGRA-RPPAAAPGRA--RPPAA 749
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462559931  116 GARAAGGAKAALGSRRAARVAPaeplsraGKPPGAEPPSAAAKGRKVKRGSRAPPARTVGPPTPAARIP 184
Cdd:PHA03378   750 APGRARPPAAAPGRARPPAAAP-------GAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMP 811
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
344-695 7.10e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 7.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  344 RSENDYLKDELDELRAEMEEmrdsyLEEDVYQLQELRRELDranKNCRILQ--YRLRKAEQKSLKVAETGQvdGELIRSL 421
Cdd:TIGR04523  376 KKENQSYKQEIKNLESQIND-----LESKIQNQEKLNQQKD---EQIKKLQqeKELLEKEIERLKETIIKN--NSEIKDL 445
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  422 EQDLKVAKdvsvrlhhelKTVEEKRAKAEDENETLRQQMIEVEISKQALQN---ELERlKESSLKR--RSTREMYKEKKT 496
Cdd:TIGR04523  446 TNQDSVKE----------LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQkqkELKS-KEKELKKlnEEKKELEEKVKD 514
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  497 FNQQNGGMerpgncrpaTKTQRKLAPRRKDDSADLRcqlqfAKEEAFL---MRKKMAKLGREKDELEQELQKYKSLYGDV 573
Cdd:TIGR04523  515 LTKKISSL---------KEKIEKLESEKKEKESKIS-----DLEDELNkddFELKKENLEKEIDEKNKEIEELKQTQKSL 580
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  574 DSplptgeaggppstREAELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERegpgrdhapsipTSPFGDS 653
Cdd:TIGR04523  581 KK-------------KQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEK------------LSSIIKN 635
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 2462559931  654 LESSTE-LRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKF 695
Cdd:TIGR04523  636 IKSKKNkLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDI 678
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
350-635 8.53e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 40.28  E-value: 8.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  350 LKDELDELRAEMEEMRDSyLEEDVYQLQELRRELDraNKNCRILQYRLRKAEQKSLKvaetgqvdGELIRSLeQDLKVAK 429
Cdd:COG1340     13 LEEKIEELREEIEELKEK-RDELNEELKELAEKRD--ELNAQVKELREEAQELREKR--------DELNEKV-KELKEER 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  430 DvsvrlhhELKT-VEEKRAKAEDENEtLRQQMIEVEISKQALQNELERLKESSLKRRSTREmyKEKKTFNQqnggmerpg 508
Cdd:COG1340     81 D-------ELNEkLNELREELDELRK-ELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPE--EEKELVEK--------- 141
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462559931  509 ncrpATKTQRKLapRRKDDSADLRCQLQFAKEEAFLMRKKMAKLGREKDELEQELQKYK----SLYGDVDSplptgeagg 584
Cdd:COG1340    142 ----IKELEKEL--EKAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHeemiELYKEADE--------- 206
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462559931  585 ppSTREA--------ELKLRLKLVEEEANILGRKIVELEVENRGLKAEMEDMRGQQERE 635
Cdd:COG1340    207 --LRKEAdelhkeivEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKE 263
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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