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Conserved domains on  [gi|2462631396|ref|XP_054183982|]
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centriole and centriolar satellite protein OFD1 isoform X6 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LisH_2 pfam16045
LisH;
82-108 9.08e-11

LisH;


:

Pssm-ID: 464992  Cd Length: 28  Bit Score: 57.09  E-value: 9.08e-11
                          10        20
                  ....*....|....*....|....*..
gi 2462631396  82 NSLVADHLQRCGYEYSLSVFFPESGLA 108
Cdd:pfam16045   2 NSLIAEYLQSQGYNYTLSVFLPESGLA 28
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 280-563 1.11e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 1.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 280 KHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNEL-- 357
Cdd:COG1196   214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYel 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 358 ----------LKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQsvnRVKELELELESVKAQSLAI 427
Cdd:COG1196   294 laelarleqdIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE---ELEEAEAELAEAEEALLEA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 428 TKQnhmLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQpapELAVFQKELRKAEKAIVVEHEEF 507
Cdd:COG1196   371 EAE---LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462631396 508 ESCRQALHKQLQDEIEH---SAQLKAQILGYKASVKSLTTQVADLKLQLKQTQTALENE 563
Cdd:COG1196   445 EEAAEEEAELEEEEEALlelLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 198-961 5.16e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member pfam02463:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1161  Bit Score: 47.27  E-value: 5.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  198 IKFESLEIKLNEYKREIEEQLRAEMCQKLKffKDTEIAKIKMEAKKKYEKEltmfqndfekacqakSEALVLREKSTLER 277
Cdd:pfam02463  158 IEEEAAGSRLKRKKKEALKKLIEETENLAE--LIIDLEELKLQELKLKEQA---------------KKALEYYQLKEKLE 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  278 IHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRrqEQNIKSFEETYDRKLKNEL 357
Cdd:pfam02463  221 LEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK--EKKLQEEELKLLAKEEEEL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  358 LKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELnQSVNRVKELELELESVKAQSLaiTKQNHMLNEK 437
Cdd:pfam02463  299 KSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL-KELEIKREAEEEEEEELEKLQ--EKLEQLEEEL 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  438 VKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRlaqpapeLAVFQKELRKAEKAIVVEHEEFESCRQALHKQ 517
Cdd:pfam02463  376 LAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQ-------LEDLLKEEKKEELEILEEEEESIELKQGKLTE 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  518 LQDEIEHSAQLKaqiLGYKASVKSLTTQVADLKLQLKQTQTALENEVYCNPKQSVIDRSVNGLINGNvVPCNGEISGDFL 597
Cdd:pfam02463  449 EKEELEKQELKL---LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVL-LALIKDGVGGRI 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  598 NNPFKQENVLARMVASRITNYPTAWVEGSSPDSDLEFVANTKARVKELQqeaeRLEKAFRSYHRRVIKNSAKSPLAAKSP 677
Cdd:pfam02463  525 ISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL----PLGARKLRLLIPKLKLPLKSIAVLEID 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  678 PSLHLLEAFKNITSSSPERHIFGEDRVVSEQPQVGTLEERNDVVEALTGSAASRLRGGTSSRRLSSTPLPKAKRSLESEM 757
Cdd:pfam02463  601 PILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQE 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  758 YLEGLgrshiaspspcpdRMPLPSPTESRHSLSIPPVSSPPEQKVglyRRQTELQDKSEFSDVDKLAFKDNEEFESSFEC 837
Cdd:pfam02463  681 LQEKA-------------ESELAKEEILRRQLEIKKKEQREKEEL---KKLKLEAEELLADRVQEAQDKINEELKLLKQK 744

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  838 VDQKQIEEQKEEEKIREQQVKERRQREERRQSNLQEVLERERRELEKLYQERKMIEESLKIKIKKELEMENELEMSNQEI 917
Cdd:pfam02463  745 IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI 824

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 2462631396  918 KDKSAHSENPLEKYMKIIQQEQDQESADKSSKKMVQEGSLVDTL 961
Cdd:pfam02463  825 EQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868
 
Name Accession Description Interval E-value
LisH_2 pfam16045
LisH;
82-108 9.08e-11

LisH;


Pssm-ID: 464992  Cd Length: 28  Bit Score: 57.09  E-value: 9.08e-11
                          10        20
                  ....*....|....*....|....*..
gi 2462631396  82 NSLVADHLQRCGYEYSLSVFFPESGLA 108
Cdd:pfam16045   2 NSLIAEYLQSQGYNYTLSVFLPESGLA 28
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 280-563 1.11e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 1.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 280 KHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNEL-- 357
Cdd:COG1196   214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYel 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 358 ----------LKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQsvnRVKELELELESVKAQSLAI 427
Cdd:COG1196   294 laelarleqdIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE---ELEEAEAELAEAEEALLEA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 428 TKQnhmLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQpapELAVFQKELRKAEKAIVVEHEEF 507
Cdd:COG1196   371 EAE---LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462631396 508 ESCRQALHKQLQDEIEH---SAQLKAQILGYKASVKSLTTQVADLKLQLKQTQTALENE 563
Cdd:COG1196   445 EEAAEEEAELEEEEEALlelLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
PTZ00121 PTZ00121
MAEBL; Provisional
 206-529 2.51e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.68  E-value: 2.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  206 KLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSEALVLRE----KSTLERIHKH 281
Cdd:PTZ00121  1367 EAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKadeaKKKAEEAKKA 1446

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  282 QEIETKEIYAQRQLLLKDMDLLRGREAELKQRVE----AFELNQKLQEEKHKSitEALRRQEQNIKSFEE---------- 347
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEeakkADEAKKKAEEAKKKA--DEAKKAAEAKKKADEakkaeeakka 1524

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  348 -----TYDRKLKNELLKYQLELKDDYIIRTNRLIEDERKNK-EKAVHLQEELIAINSKKEELNQS----VNRVKELELEL 417
Cdd:PTZ00121  1525 deakkAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKaEEAKKAEEDKNMALRKAEEAKKAeearIEEVMKLYEEE 1604

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  418 ESVKAQSLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLA-------QPAPELAVFQ 490
Cdd:PTZ00121  1605 KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAkkaeedkKKAEEAKKAE 1684

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 2462631396  491 KELRKAEKAIVVEHEEFESCRQaLHKQLQDEIEHSAQLK 529
Cdd:PTZ00121  1685 EDEKKAAEALKKEAEEAKKAEE-LKKKEAEEKKKAEELK 1722
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 268-561 3.19e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 3.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  268 VLRE-KSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIkSFE 346
Cdd:TIGR02168  194 ILNElERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL-EEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  347 ETYDRKLKNELLKYQLELKDdYIIRTNRLIEDERKNKEKAVHLQEELIAIN-------SKKEELNQSVNRVKElelELES 419
Cdd:TIGR02168  273 RLEVSELEEEIEELQKELYA-LANEISRLEQQKQILRERLANLERQLEELEaqleeleSKLDELAEELAELEE---KLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  420 VKAQSLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQN-KLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEK 498
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKvAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462631396  499 AIVVE-----HEEFESCRQALHKQLQDEIEHSAQLKAQilgyKASVKSLTTQVADLKLQLKQTQTALE 561
Cdd:TIGR02168  429 KLEEAelkelQAELEELEEELEELQEELERLEEALEEL----REELEEAEQALDAAERELAQLQARLD 492
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 198-961 5.16e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 47.27  E-value: 5.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  198 IKFESLEIKLNEYKREIEEQLRAEMCQKLKffKDTEIAKIKMEAKKKYEKEltmfqndfekacqakSEALVLREKSTLER 277
Cdd:pfam02463  158 IEEEAAGSRLKRKKKEALKKLIEETENLAE--LIIDLEELKLQELKLKEQA---------------KKALEYYQLKEKLE 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  278 IHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRrqEQNIKSFEETYDRKLKNEL 357
Cdd:pfam02463  221 LEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK--EKKLQEEELKLLAKEEEEL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  358 LKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELnQSVNRVKELELELESVKAQSLaiTKQNHMLNEK 437
Cdd:pfam02463  299 KSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL-KELEIKREAEEEEEEELEKLQ--EKLEQLEEEL 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  438 VKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRlaqpapeLAVFQKELRKAEKAIVVEHEEFESCRQALHKQ 517
Cdd:pfam02463  376 LAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQ-------LEDLLKEEKKEELEILEEEEESIELKQGKLTE 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  518 LQDEIEHSAQLKaqiLGYKASVKSLTTQVADLKLQLKQTQTALENEVYCNPKQSVIDRSVNGLINGNvVPCNGEISGDFL 597
Cdd:pfam02463  449 EKEELEKQELKL---LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVL-LALIKDGVGGRI 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  598 NNPFKQENVLARMVASRITNYPTAWVEGSSPDSDLEFVANTKARVKELQqeaeRLEKAFRSYHRRVIKNSAKSPLAAKSP 677
Cdd:pfam02463  525 ISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL----PLGARKLRLLIPKLKLPLKSIAVLEID 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  678 PSLHLLEAFKNITSSSPERHIFGEDRVVSEQPQVGTLEERNDVVEALTGSAASRLRGGTSSRRLSSTPLPKAKRSLESEM 757
Cdd:pfam02463  601 PILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQE 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  758 YLEGLgrshiaspspcpdRMPLPSPTESRHSLSIPPVSSPPEQKVglyRRQTELQDKSEFSDVDKLAFKDNEEFESSFEC 837
Cdd:pfam02463  681 LQEKA-------------ESELAKEEILRRQLEIKKKEQREKEEL---KKLKLEAEELLADRVQEAQDKINEELKLLKQK 744

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  838 VDQKQIEEQKEEEKIREQQVKERRQREERRQSNLQEVLERERRELEKLYQERKMIEESLKIKIKKELEMENELEMSNQEI 917
Cdd:pfam02463  745 IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI 824

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 2462631396  918 KDKSAHSENPLEKYMKIIQQEQDQESADKSSKKMVQEGSLVDTL 961
Cdd:pfam02463  825 EQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 205-441 6.05e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.04  E-value: 6.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 205 IKLNEYKREIEEQLRAEMCQKLKffKDTEIAKIKMEAKKKYEK-----ELTMFQNDFEKACQAKsealVLREKSTLERIH 279
Cdd:pfam17380 353 IRQEERKRELERIRQEEIAMEIS--RMRELERLQMERQQKNERvrqelEAARKVKILEEERQRK----IQQQKVEMEQIR 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 280 KHQEiETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQklQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLK 359
Cdd:pfam17380 427 AEQE-EARQREVRRLEEERAREMERVRLEEQERQQQVERLRQ--QEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE 503

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 360 yqlelkddyiiRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELEL-ELESVKAQSLAITKQNHMLN--E 436
Cdd:pfam17380 504 -----------RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMeERRRIQEQMRKATEERSRLEamE 572


                  ....*
gi 2462631396 437 KVKEM 441
Cdd:pfam17380 573 REREM 577
 
Name Accession Description Interval E-value
LisH_2 pfam16045
LisH;
82-108 9.08e-11

LisH;


Pssm-ID: 464992  Cd Length: 28  Bit Score: 57.09  E-value: 9.08e-11
                          10        20
                  ....*....|....*....|....*..
gi 2462631396  82 NSLVADHLQRCGYEYSLSVFFPESGLA 108
Cdd:pfam16045   2 NSLIAEYLQSQGYNYTLSVFLPESGLA 28
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 280-563 1.11e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 1.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 280 KHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNEL-- 357
Cdd:COG1196   214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYel 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 358 ----------LKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQsvnRVKELELELESVKAQSLAI 427
Cdd:COG1196   294 laelarleqdIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE---ELEEAEAELAEAEEALLEA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 428 TKQnhmLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQpapELAVFQKELRKAEKAIVVEHEEF 507
Cdd:COG1196   371 EAE---LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462631396 508 ESCRQALHKQLQDEIEH---SAQLKAQILGYKASVKSLTTQVADLKLQLKQTQTALENE 563
Cdd:COG1196   445 EEAAEEEAELEEEEEALlelLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
PTZ00121 PTZ00121
MAEBL; Provisional
 206-529 2.51e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.68  E-value: 2.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  206 KLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSEALVLRE----KSTLERIHKH 281
Cdd:PTZ00121  1367 EAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKadeaKKKAEEAKKA 1446

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  282 QEIETKEIYAQRQLLLKDMDLLRGREAELKQRVE----AFELNQKLQEEKHKSitEALRRQEQNIKSFEE---------- 347
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEeakkADEAKKKAEEAKKKA--DEAKKAAEAKKKADEakkaeeakka 1524

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  348 -----TYDRKLKNELLKYQLELKDDYIIRTNRLIEDERKNK-EKAVHLQEELIAINSKKEELNQS----VNRVKELELEL 417
Cdd:PTZ00121  1525 deakkAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKaEEAKKAEEDKNMALRKAEEAKKAeearIEEVMKLYEEE 1604

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  418 ESVKAQSLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLA-------QPAPELAVFQ 490
Cdd:PTZ00121  1605 KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAkkaeedkKKAEEAKKAE 1684

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 2462631396  491 KELRKAEKAIVVEHEEFESCRQaLHKQLQDEIEHSAQLK 529
Cdd:PTZ00121  1685 EDEKKAAEALKKEAEEAKKAEE-LKKKEAEEKKKAEELK 1722
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 268-561 3.19e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 3.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  268 VLRE-KSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIkSFE 346
Cdd:TIGR02168  194 ILNElERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL-EEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  347 ETYDRKLKNELLKYQLELKDdYIIRTNRLIEDERKNKEKAVHLQEELIAIN-------SKKEELNQSVNRVKElelELES 419
Cdd:TIGR02168  273 RLEVSELEEEIEELQKELYA-LANEISRLEQQKQILRERLANLERQLEELEaqleeleSKLDELAEELAELEE---KLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  420 VKAQSLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQN-KLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEK 498
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKvAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462631396  499 AIVVE-----HEEFESCRQALHKQLQDEIEHSAQLKAQilgyKASVKSLTTQVADLKLQLKQTQTALE 561
Cdd:TIGR02168  429 KLEEAelkelQAELEELEEELEELQEELERLEEALEEL----REELEEAEQALDAAERELAQLQARLD 492
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
271-563 4.68e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 4.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 271 EKSTLERIHKHQEIETKEIYAQRQL-----LLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSF 345
Cdd:PRK03918  199 EKELEEVLREINEISSELPELREELeklekEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEEL 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 346 EETYDR--KLKNELLKYQL--ELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVK 421
Cdd:PRK03918  279 EEKVKElkELKEKAEEYIKlsEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELE 358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 422 AQSLAItkqnHMLNEKVKEMSDYSLLKEEKLELLAQNKLL-----KQQLEESRNENLRLLNRLAQPAPELAVFQKELRKA 496
Cdd:PRK03918  359 ERHELY----EEAKAKKEELERLKKRLTGLTPEKLEKELEelekaKEEIEEEISKITARIGELKKEIKELKKAIEELKKA 434

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462631396 497 EKAIVVeheefesCRQALHKQLQDEIehSAQLKAQILGYKASVKSLTTQVADLKLQLKQTQTALENE 563
Cdd:PRK03918  435 KGKCPV-------CGRELTEEHRKEL--LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKE 492
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 304-561 2.08e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 2.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  304 RGREAELK--------QRVE--AFELNQKLqeekhksitEALRRQEQNIKSFeetydRKLKNELLKYQLELkddYIIRTN 373
Cdd:TIGR02168  173 RRKETERKlertrenlDRLEdiLNELERQL---------KSLERQAEKAERY-----KELKAELRELELAL---LVLRLE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  374 RLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNrvkELELELESVKAQSLAITKQNHMLNEKVKEMSD----YSLLKE 449
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLE---ELRLEVSELEEEIEELQKELYALANEISRLEQqkqiLRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  450 EKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLK 529
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          250       260       270
                   ....*....|....*....|....*....|..
gi 2462631396  530 AQILGYKASVKSLTTQVADLKLQLKQTQTALE 561
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIE 424
PTZ00121 PTZ00121
MAEBL; Provisional
 209-499 2.15e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 2.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  209 EYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEK-----ELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQE 283
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEernneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  284 IETKEiYAQRQLLLKDMDLLRgREAELKQRVEafELNQKLQEEKHKSitEALRRQEQniksfeetyDRKLKNELLKYQLE 363
Cdd:PTZ00121  1289 KKKAD-EAKKAEEKKKADEAK-KKAEEAKKAD--EAKKKAEEAKKKA--DAAKKKAE---------EAKKAAEAAKAEAE 1353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  364 LKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSLAiTKQNHMLNEKVKEMSD 443
Cdd:PTZ00121  1354 AAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA-KKKADEAKKKAEEKKK 1432

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462631396  444 YSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEKA 499
Cdd:PTZ00121  1433 ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA 1488
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 270-561 4.61e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 4.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  270 REKSTLERIH----KHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFelnQKLQEEKHKSITEALRRQEQ---NI 342
Cdd:TIGR02169  205 REREKAERYQallkEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL---TEEISELEKRLEEIEQLLEElnkKI 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  343 KSFEETYDRKLKNELLKYQLElkddyIIRTNRLIEDERKNKEKAVHLQEELIA-INSKKEELNQSVNRVKELELELESVK 421
Cdd:TIGR02169  282 KDLGEEEQLRVKEKIGELEAE-----IASLERSIAEKERELEDAEERLAKLEAeIDKLLAEIEELEREIEEERKRRDKLT 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  422 AqslAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEKAIV 501
Cdd:TIGR02169  357 E---EYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE 433

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  502 VEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQVADLKLQLKQTQTALE 561
Cdd:TIGR02169  434 AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELA 493
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 198-961 5.16e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 47.27  E-value: 5.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  198 IKFESLEIKLNEYKREIEEQLRAEMCQKLKffKDTEIAKIKMEAKKKYEKEltmfqndfekacqakSEALVLREKSTLER 277
Cdd:pfam02463  158 IEEEAAGSRLKRKKKEALKKLIEETENLAE--LIIDLEELKLQELKLKEQA---------------KKALEYYQLKEKLE 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  278 IHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRrqEQNIKSFEETYDRKLKNEL 357
Cdd:pfam02463  221 LEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK--EKKLQEEELKLLAKEEEEL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  358 LKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELnQSVNRVKELELELESVKAQSLaiTKQNHMLNEK 437
Cdd:pfam02463  299 KSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL-KELEIKREAEEEEEEELEKLQ--EKLEQLEEEL 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  438 VKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRlaqpapeLAVFQKELRKAEKAIVVEHEEFESCRQALHKQ 517
Cdd:pfam02463  376 LAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQ-------LEDLLKEEKKEELEILEEEEESIELKQGKLTE 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  518 LQDEIEHSAQLKaqiLGYKASVKSLTTQVADLKLQLKQTQTALENEVYCNPKQSVIDRSVNGLINGNvVPCNGEISGDFL 597
Cdd:pfam02463  449 EKEELEKQELKL---LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVL-LALIKDGVGGRI 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  598 NNPFKQENVLARMVASRITNYPTAWVEGSSPDSDLEFVANTKARVKELQqeaeRLEKAFRSYHRRVIKNSAKSPLAAKSP 677
Cdd:pfam02463  525 ISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL----PLGARKLRLLIPKLKLPLKSIAVLEID 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  678 PSLHLLEAFKNITSSSPERHIFGEDRVVSEQPQVGTLEERNDVVEALTGSAASRLRGGTSSRRLSSTPLPKAKRSLESEM 757
Cdd:pfam02463  601 PILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQE 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  758 YLEGLgrshiaspspcpdRMPLPSPTESRHSLSIPPVSSPPEQKVglyRRQTELQDKSEFSDVDKLAFKDNEEFESSFEC 837
Cdd:pfam02463  681 LQEKA-------------ESELAKEEILRRQLEIKKKEQREKEEL---KKLKLEAEELLADRVQEAQDKINEELKLLKQK 744

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  838 VDQKQIEEQKEEEKIREQQVKERRQREERRQSNLQEVLERERRELEKLYQERKMIEESLKIKIKKELEMENELEMSNQEI 917
Cdd:pfam02463  745 IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI 824

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 2462631396  918 KDKSAHSENPLEKYMKIIQQEQDQESADKSSKKMVQEGSLVDTL 961
Cdd:pfam02463  825 EQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 205-441 6.05e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.04  E-value: 6.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 205 IKLNEYKREIEEQLRAEMCQKLKffKDTEIAKIKMEAKKKYEK-----ELTMFQNDFEKACQAKsealVLREKSTLERIH 279
Cdd:pfam17380 353 IRQEERKRELERIRQEEIAMEIS--RMRELERLQMERQQKNERvrqelEAARKVKILEEERQRK----IQQQKVEMEQIR 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 280 KHQEiETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQklQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLK 359
Cdd:pfam17380 427 AEQE-EARQREVRRLEEERAREMERVRLEEQERQQQVERLRQ--QEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE 503

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 360 yqlelkddyiiRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELEL-ELESVKAQSLAITKQNHMLN--E 436
Cdd:pfam17380 504 -----------RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMeERRRIQEQMRKATEERSRLEamE 572


                  ....*
gi 2462631396 437 KVKEM 441
Cdd:pfam17380 573 REREM 577
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
201-562 1.18e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.21  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 201 ESLEIKLNEYKREIEEqlRAEMCQKLKffkdtEIAKIKMEAKKKYEkELTMFQNDFEKACQAKSEALVLREKSTLERIHK 280
Cdd:PRK03918  317 SRLEEEINGIEERIKE--LEEKEERLE-----ELKKKLKELEKRLE-ELEERHELYEEAKAKKEELERLKKRLTGLTPEK 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 281 HQEiETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELN---------------QKLQEEKHKSI----TEALRRQEQN 341
Cdd:PRK03918  389 LEK-ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEEHRKELleeyTAELKRIEKE 467

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 342 IKSFEETyDRKLKNELLKYQLELKDDYIIRTNRLIEDE----------------RKNKEKAVHLQEELIAINSKKEELNQ 405
Cdd:PRK03918  468 LKEIEEK-ERKLRKELRELEKVLKKESELIKLKELAEQlkeleeklkkynleelEKKAEEYEKLKEKLIKLKGEIKSLKK 546

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 406 SVNRVKELELELEsvkaqslAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLlkQQLEESRNENLRLLN---RLAQP 482
Cdd:PRK03918  547 ELEKLEELKKKLA-------ELEKKLDELEEELAELLKELEELGFESVEELEERL--KELEPFYNEYLELKDaekELERE 617

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 483 APELAVFQKELRKAEKAIVVEHEEFESCRQALH--KQLQDEIEHsAQLKAQILGYKASVKSLTTQVADLKLQLKQTQTAL 560
Cdd:PRK03918  618 EKELKKLEEELDKAFEELAETEKRLEELRKELEelEKKYSEEEY-EELREEYLELSRELAGLRAELEELEKRREEIKKTL 696


                  ..
gi 2462631396 561 EN 562
Cdd:PRK03918  697 EK 698
PRK12704 PRK12704
phosphodiesterase; Provisional
 325-495 1.62e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 1.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 325 EEKHKSITEALRRQEQNIKSFEETydrKLKNELLKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELN 404
Cdd:PRK12704   37 EEEAKRILEEAKKEAEAIKKEALL---EAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELE 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 405 QSVNRVKELELELESVKAqslaitKQNHMLNEKVKEMSDYSllkeEKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAP 484
Cdd:PRK12704  114 KKEKELEQKQQELEKKEE------ELEELIEEQLQELERIS----GLTAEEAKEILLEKVEEEARHEAAVLIKEIEEEAK 183

                         170
                  ....*....|.
gi 2462631396 485 ELAvfQKELRK 495
Cdd:PRK12704  184 EEA--DKKAKE 192
PTZ00121 PTZ00121
MAEBL; Provisional
 204-528 1.79e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 1.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  204 EIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSE-ALVLREKSTLERIHKHQ 282
Cdd:PTZ00121  1514 EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDkNMALRKAEEAKKAEEAR 1593

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  283 EIETKEIYAQRqlllKDMDLLRGREAElKQRVEAFELnqKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQL 362
Cdd:PTZ00121  1594 IEEVMKLYEEE----KKMKAEEAKKAE-EAKIKAEEL--KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  363 ELKDDyiiRTNRLIEDERKNKEKAVHLQEELiainSKKEELNQSVNRVKELELElESVKAQSLaiTKQNHMLNEKVKEMS 442
Cdd:PTZ00121  1667 AKKAE---EDKKKAEEAKKAEEDEKKAAEAL----KKEAEEAKKAEELKKKEAE-EKKKAEEL--KKAEEENKIKAEEAK 1736

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  443 DYSLLKeeklellaqnkllKQQLEESRNENLRlLNRLAQPAPELAVFQKELRKAEKAIVVE--HEEFESCRQALHKQLQD 520
Cdd:PTZ00121  1737 KEAEED-------------KKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEKEAVIEEelDEEDEKRRMEVDKKIKD 1802


                   ....*...
gi 2462631396  521 EIEHSAQL 528
Cdd:PTZ00121  1803 IFDNFANI 1810
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 283-516 7.77e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 7.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  283 EIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEEtYDRKLKNELLKYQL 362
Cdd:TIGR02168  697 EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA-EIEELEERLEEAEE 775

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  363 ELKDdyiirtnrlIEDER-KNKEKAVHLQEELIAINSKKEELNQSVNRVKE----LELELESVKAQSLAITKQNHMLNEK 437
Cdd:TIGR02168  776 ELAE---------AEAEIeELEAQIEQLKEELKALREALDELRAELTLLNEeaanLRERLESLERRIAATERRLEDLEEQ 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  438 VKEMS-DYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAPELAVFQKELRKAEKAIVVEHEEFESCRQALHK 516
Cdd:TIGR02168  847 IEELSeDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926
PTZ00121 PTZ00121
MAEBL; Provisional
 199-563 4.44e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 4.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  199 KFESLEIKLNEYKREIEE-QLRAEMCQKLKFFKDTEIAKIKMEAKKKYEKEltmfQNDFEKACQAKSEALVLREKStlER 277
Cdd:PTZ00121  1316 KADEAKKKAEEAKKKADAaKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKA----EAAEKKKEEAKKKADAAKKKA--EE 1389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  278 IHKHQEIETK-EIYAQRQLLLKDMDLLRGREAELKQRVE----AFELNQKLQEEKH----KSITEALRRQEQNIKSFEET 348
Cdd:PTZ00121  1390 KKKADEAKKKaEEDKKKADELKKAAAAKKKADEAKKKAEekkkADEAKKKAEEAKKadeaKKKAEEAKKAEEAKKKAEEA 1469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  349 Y---DRKLKNELLKYQLELKDDyiIRTNRLIEDERKNKEKAVHLQEELIAINSKK--EELNQSVNRVKELELELESVKAQ 423
Cdd:PTZ00121  1470 KkadEAKKKAEEAKKADEAKKK--AEEAKKKADEAKKAAEAKKKADEAKKAEEAKkaDEAKKAEEAKKADEAKKAEEKKK 1547

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  424 SLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQP--APELAVFQKELRKAEKaiV 501
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKmkAEEAKKAEEAKIKAEE--L 1625

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462631396  502 VEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQVADLKLQLKQTQTALENE 563
Cdd:PTZ00121  1626 KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 179-407 5.42e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 40.61  E-value: 5.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 179 LAEKLQLIDDQFADAYPQRIKFESLEIKLNEYK-----------REIEEQLRAEMCQKLKFFKDTEIAKIKMEA-KKKYE 246
Cdd:PLN03229  509 LMEKIEKLKDEFNKRLSRAPNYLSLKYKLDMLNefsrakalsekKSKAEKLKAEINKKFKEVMDRPEIKEKMEAlKAEVA 588

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 247 KELTMFQNDFEKAcqaksealvLREKstLERIHKHQEIETKEIyaqrqllLKDMDL----LRGREAELKQRVEAFELNQK 322
Cdd:PLN03229  589 SSGASSGDELDDD---------LKEK--VEKMKKEIELELAGV-------LKSMGLevigVTKKNKDTAEQTPPPNLQEK 650

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396 323 ---LQEEKHKSITEALRRQEQNIK----SFEETYDRKLKNELLKYQLELKDDYIIRTNRLIEDERKNKEKAVHLQEELIA 395
Cdd:PLN03229  651 iesLNEEINKKIERVIRSSDLKSKiellKLEVAKASKTPDVTEKEKIEALEQQIKQKIAEALNSSELKEKFEELEAELAA 730

                         250
                  ....*....|..
gi 2462631396 396 INSKKEELNQSV 407
Cdd:PLN03229  731 ARETAAESNGSL 742
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 239-555 6.06e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 40.72  E-value: 6.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  239 MEAKKKYEKELTMFQNDFEKACQakseaLVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGREAELKQRVEAFE 318
Cdd:TIGR00618  158 LKAKSKEKKELLMNLFPLDQYTQ-----LALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLR 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  319 LNQKLQEEKHKSITEALRRQEQNIKSFEETydRKLKNELLKYQLELKDdyIIRTNRLIEDERKnKEKAVHLQEELIAINS 398
Cdd:TIGR00618  233 EALQQTQQSHAYLTQKREAQEEQLKKQQLL--KQLRARIEELRAQEAV--LEETQERINRARK-AAPLAAHIKAVTQIEQ 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  399 KKEELNQSVN-RVKELELEL---ESVKAQSLAITKQNHMLNE----------------KVKEMSDYSLLKEEKLELLAQN 458
Cdd:TIGR00618  308 QAQRIHTELQsKMRSRAKLLmkrAAHVKQQSSIEEQRRLLQTlhsqeihirdahevatSIREISCQQHTLTQHIHTLQQQ 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631396  459 K-LLKQQLEESRNENLRLLNRLAQPAPELAVF---QKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILG 534
Cdd:TIGR00618  388 KtTLTQKLQSLCKELDILQREQATIDTRTSAFrdlQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS 467

                          330       340
                   ....*....|....*....|.
gi 2462631396  535 YKAsvksLTTQVADLKLQLKQ 555
Cdd:TIGR00618  468 LKE----REQQLQTKEQIHLQ 484
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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