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Conserved domains on  [gi|2462632128|ref|XP_054184333|]
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histone demethylase UTY isoform X26 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 18770923)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|22404999|21153002
SCOP:  4001344

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 168-441 2.19e-25

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 107.12  E-value: 2.19e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  168 LRLGLMFKVNTDYKSSLKHFQLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLpaqvKATVLQQLG 247
Cdd:COG2956     12 YFKGLNYLLNGQPDKAIDLLEEAL-ELDP---ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPD----RAEALLELA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  248 WMHHNMDLVgDKAtkesyaIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQ 327
Cdd:COG2956     84 QDYLKAGLL-DRA------EELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLE 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  328 QNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKrcSNTSTLAARIKFLQAQLCNLPQ--SS 405
Cdd:COG2956    157 QGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD--PDYLPALPRLAELYEKLGDPEEalEL 234

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 2462632128  406 LQNKTKLLPSIEEAWSLpipAELTSRQGAMNTAQQQ 441
Cdd:COG2956    235 LRKALELDPSDDLLLAL---ADLLERKEGLEAALAL 267
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 95-230 3.40e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.44  E-value: 3.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   95 QLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFcraKEIHLRLGLMF 174
Cdd:COG4783      9 ALAQALLLAGDYDEAEALLEKALELDPD---NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE---PEARLNLGLAL 82

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462632128  175 KVNTDYKSSLKHFQLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQ 230
Cdd:COG4783     83 LKAGDYDEALALLEKAL-KLDP---EHPEAYLRLARAYRALGRPDEAIAALEKALE 134
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 168-441 2.19e-25

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 107.12  E-value: 2.19e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  168 LRLGLMFKVNTDYKSSLKHFQLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLpaqvKATVLQQLG 247
Cdd:COG2956     12 YFKGLNYLLNGQPDKAIDLLEEAL-ELDP---ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPD----RAEALLELA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  248 WMHHNMDLVgDKAtkesyaIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQ 327
Cdd:COG2956     84 QDYLKAGLL-DRA------EELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLE 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  328 QNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKrcSNTSTLAARIKFLQAQLCNLPQ--SS 405
Cdd:COG2956    157 QGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD--PDYLPALPRLAELYEKLGDPEEalEL 234

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 2462632128  406 LQNKTKLLPSIEEAWSLpipAELTSRQGAMNTAQQQ 441
Cdd:COG2956    235 LRKALELDPSDDLLLAL---ADLLERKEGLEAALAL 267
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 95-230 3.40e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.44  E-value: 3.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   95 QLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFcraKEIHLRLGLMF 174
Cdd:COG4783      9 ALAQALLLAGDYDEAEALLEKALELDPD---NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE---PEARLNLGLAL 82

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462632128  175 KVNTDYKSSLKHFQLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQ 230
Cdd:COG4783     83 LKAGDYDEALALLEKAL-KLDP---EHPEAYLRLARAYRALGRPDEAIAALEKALE 134
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 84-419 9.53e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 56.63  E-value: 9.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   84 AEGKVESD--FFCQLGHFNLLLEDYSKALSAYQRYYSLQAdywKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFC 161
Cdd:TIGR02917  355 ALGLDPDDpaALSLLGEAYLALGDFEKAAEYLAKATELDP---ENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELG 431

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  162 RAKEI----HLRLGLMFKVNTDYKSSLKHfqlalidcnpcTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTEnlPAQ 237
Cdd:TIGR02917  432 RADLLlilsYLRSGQFDKALAAAKKLEKK-----------QPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIE--PDF 498

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  238 VKATVLQQlgwmhhNMDLVGDKATKesyAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADT 317
Cdd:TIGR02917  499 FPAAANLA------RIDIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEP 569

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  318 WCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAArsKRCSNTSTLAARIKFLQAq 397
Cdd:TIGR02917  570 ALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLL--ALQPDSALALLLLADAYA- 646

                          330       340
                   ....*....|....*....|..
gi 2462632128  398 lcnlpqsSLQNKTKLLPSIEEA 419
Cdd:TIGR02917  647 -------VMKNYAKAITSLKRA 661
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 167-231 4.34e-03

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 40.80  E-value: 4.34e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462632128  167 HLRLGLMFK-VNTDYKSSLKHFQLALIDCNPCTLS--NAE---IQFHIAHLYEtqrKYHSAKEAYEQLLQT 231
Cdd:cd24145     10 ILRKALYYEsDKPDPQKALKYYKEALEQADELGMDpfSDEvtgIRIKIAEMLE---KLGMYKAAYEVLERL 77
TPR_1 pfam00515
Tetratricopeptide repeat;
127-160 5.15e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 5.15e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2462632128  127 AAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSF 160
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_17 pfam13431
Tetratricopeptide repeat;
269-300 7.96e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 35.21  E-value: 7.96e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2462632128  269 YLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA 300
Cdd:pfam13431    1 LYLKALELDPNNADAYYNLAVLLLELGQSETA 32
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 168-441 2.19e-25

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 107.12  E-value: 2.19e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  168 LRLGLMFKVNTDYKSSLKHFQLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLpaqvKATVLQQLG 247
Cdd:COG2956     12 YFKGLNYLLNGQPDKAIDLLEEAL-ELDP---ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPD----RAEALLELA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  248 WMHHNMDLVgDKAtkesyaIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQ 327
Cdd:COG2956     84 QDYLKAGLL-DRA------EELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLE 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  328 QNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKrcSNTSTLAARIKFLQAQLCNLPQ--SS 405
Cdd:COG2956    157 QGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD--PDYLPALPRLAELYEKLGDPEEalEL 234

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 2462632128  406 LQNKTKLLPSIEEAWSLpipAELTSRQGAMNTAQQQ 441
Cdd:COG2956    235 LRKALELDPSDDLLLAL---ADLLERKEGLEAALAL 267
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 127-377 7.05e-25

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 105.58  E-value: 7.05e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  127 AAFLYG---LGLVYFYYNAFHWAIKAFQDVLYVDPSfcrAKEIHLRLGLMFKVNTDYKSSLKHFQlALIDCNPctlSNAE 203
Cdd:COG2956      5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQ-KLLERDP---DRAE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  204 IQFHIAHLYETQRKYHSAKEAYEQLLQTE--NLPAQVK-ATVLQQLG-WmhhnmdlvgDKatkesyAIQYLQKSLEADPN 279
Cdd:COG2956     78 ALLELAQDYLKAGLLDRAEELLEKLLELDpdDAEALRLlAEIYEQEGdW---------EK------AIEVLERLLKLGPE 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  280 SGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLY 359
Cdd:COG2956    143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                          250
                   ....*....|....*...
gi 2462632128  360 ESCNQPQDAIKCYLNAAR 377
Cdd:COG2956    223 EKLGDPEEALELLRKALE 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
201-445 1.27e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 104.32  E-value: 1.27e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  201 NAEIQFHIAHLYETQRKYHSAKEAYEQLLQTEnlPAQVKAtvLQQLGWMHHNMdlvGDKATkesyAIQYLQKSLEADPNS 280
Cdd:COG0457      7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELD--PDDAEA--LYNLGLAYLRL---GRYEE----ALADYEQALELDPDD 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  281 GQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE 360
Cdd:COG0457     76 AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  361 SCNQPQDAIKCYlNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQ 440
Cdd:COG0457    156 KLGRYEEALELL-EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALR 234


                   ....*
gi 2462632128  441 QSLSL 445
Cdd:COG0457    235 LAALA 239
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 266-372 7.27e-20

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 86.60  E-value: 7.27e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  266 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 345
Cdd:COG4235      2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                           90       100
                   ....*....|....*....|....*..
gi 2462632128  346 HGHAAAWMDLGTLYESCNQPQDAIKCY 372
Cdd:COG4235     82 PDNPEALYLLGLAAFQQGDYAEAIAAW 108
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 72-377 2.37e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 89.40  E-value: 2.37e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   72 KAVRCYESLILKAEGKVESDFfcQLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQ 151
Cdd:COG2956     26 KAIDLLEEALELDPETVEAHL--ALGNLYRRRGEYDRAIRIHQKLLERDPD---RAEALLELAQDYLKAGLLDRAEELLE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  152 DVLYVDPsfcrakeihlrlglmfkvntdyksslkhfqlalidcnpctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQT 231
Cdd:COG2956    101 KLLELDP-----------------------------------------DDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  232 ENLPAQV---KATVLQQLgwmhhnmdlvGDKATkesyAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSI 308
Cdd:COG2956    140 GPENAHAyceLAELYLEQ----------GDYDE----AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL 205

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462632128  309 DKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGhAAAWMDLGTLYESCNQPQDAIKCYLNAAR 377
Cdd:COG2956    206 EQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLR 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
274-375 2.19e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 85.83  E-value: 2.19e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  274 LEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWM 353
Cdd:COG0457      1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                           90       100
                   ....*....|....*....|..
gi 2462632128  354 DLGTLYESCNQPQDAIKCYLNA 375
Cdd:COG0457     81 NLGLALQALGRYEEALEDYDKA 102
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
125-316 2.67e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 85.83  E-value: 2.67e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  125 KNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAkeiHLRLGLMFKVNTDYKSSLKHFQLALiDCNPctlSNAEI 204
Cdd:COG0457      6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---LYNLGLAYLRLGRYEEALADYEQAL-ELDP---DDAEA 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  205 QFHIAHLYETQRKYHSAKEAYEQLLQTEnlPAQVKAtvLQQLGWMHHNMdlvGDKATkesyAIQYLQKSLEADPNSGQSW 284
Cdd:COG0457     79 LNNLGLALQALGRYEEALEDYDKALELD--PDDAEA--LYNLGLALLEL---GRYDE----AIEAYERALELDPDDADAL 147

                          170       180       190
                   ....*....|....*....|....*....|..
gi 2462632128  285 YFLGRCYSSIGKVQDAFISYRQSIDKSEASAD 316
Cdd:COG0457    148 YNLGIALEKLGRYEEALELLEKLEAAALAALL 179
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 186-421 5.89e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 89.28  E-value: 5.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  186 HFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVK--------ATVLQQLGWMHHNMDLVG 257
Cdd:COG3914      6 LLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALlalaageaAAAAAALLLLAALLELAA 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  258 DKATKESY---AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDA 334
Cdd:COG3914     86 LLLQALGRyeeALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEA 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  335 LQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAArsKRCSNTSTLAARIKFLQAQLCNLPQSS-LQNKTKLL 413
Cdd:COG3914    166 IAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRAL--ELDPDNADAHSNLLFALRQACDWEVYDrFEELLAAL 243


                   ....*...
gi 2462632128  414 PSIEEAWS 421
Cdd:COG3914    244 ARGPSELS 251
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 266-377 3.21e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 73.69  E-value: 3.21e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  266 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 345
Cdd:COG4783     23 AEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLD 102

                           90       100       110
                   ....*....|....*....|....*....|..
gi 2462632128  346 HGHAAAWMDLGTLYESCNQPQDAIKCYLNAAR 377
Cdd:COG4783    103 PEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 202-345 9.49e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.45  E-value: 9.49e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  202 AEIQFHIAHLYETQRKYHSAKEAYEQLLQTEnlPAQVKAtvLQQLGWMHHNMdlvGDKATkesyAIQYLQKSLEADPNSG 281
Cdd:COG4783      4 AEALYALAQALLLAGDYDEAEALLEKALELD--PDNPEA--FALLGEILLQL---GDLDE----AIVLLHEALELDPDEP 72

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462632128  282 QSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 345
Cdd:COG4783     73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
72-277 1.02e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 66.18  E-value: 1.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   72 KAVRCYESLILKAEGKVESdfFCQLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQ 151
Cdd:COG0457     26 EAIEDYEKALELDPDDAEA--LYNLGLAYLRLGRYEEALADYEQALELDPD---DAEALNNLGLALQALGRYEEALEDYD 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  152 DVLYVDPSFCRAK----EIHLRLGlmfkvntDYKSSLKHFQLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQ 227
Cdd:COG0457    101 KALELDPDDAEALynlgLALLELG-------RYDEAIEAYERAL-ELDP---DDADALYNLGIALEKLGRYEEALELLEK 169

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462632128  228 LLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEAD 277
Cdd:COG0457    170 LEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAAL 219
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 72-277 4.58e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.75  E-value: 4.58e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   72 KAVRCYESLILKAEGKVESdfFCQLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQ 151
Cdd:COG2956     94 RAEELLEKLLELDPDDAEA--LRLLAEIYEQEGDWEKAIEVLERLLKLGPE---NAHAYCELAELYLEQGDYDEAIEALE 168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  152 DVLYVDPSFCRAK----EIHLRLGlmfkvntDYKSSLKHFQlALIDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQ 227
Cdd:COG2956    169 KALKLDPDCARALlllaELYLEQG-------DYEEAIAALE-RALEQDP---DYLPALPRLAELYEKLGDPEEALELLRK 237

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462632128  228 LLQTENLPAQV--KATVLQQLGwmhhnmdlvGDKAtkesyAIQYLQKSLEAD 277
Cdd:COG2956    238 ALELDPSDDLLlaLADLLERKE---------GLEA-----ALALLERQLRRH 275
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
266-345 1.29e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.03  E-value: 1.29e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  266 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAfISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 345
Cdd:COG3063     11 AEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELD 89
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 95-230 3.40e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.44  E-value: 3.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   95 QLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFcraKEIHLRLGLMF 174
Cdd:COG4783      9 ALAQALLLAGDYDEAEALLEKALELDPD---NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE---PEARLNLGLAL 82

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462632128  175 KVNTDYKSSLKHFQLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQ 230
Cdd:COG4783     83 LKAGDYDEALALLEKAL-KLDP---EHPEAYLRLARAYRALGRPDEAIAALEKALE 134
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
275-370 2.32e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 58.77  E-value: 2.32e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  275 EADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMD 354
Cdd:COG4785     67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                           90
                   ....*....|....*.
gi 2462632128  355 LGTLYESCNQPQDAIK 370
Cdd:COG4785    147 RGIALYYLGRYELAIA 162
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 95-191 4.23e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 4.23e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   95 QLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAkeiHLRLGLMF 174
Cdd:COG4235     22 LLGRAYLRLGRYDEALAAYEKALRLDPD---NADALLDLAEALLAAGDTEEAEELLERALALDPDNPEA---LYLLGLAA 95

                           90
                   ....*....|....*..
gi 2462632128  175 KVNTDYKSSLKHFQLAL 191
Cdd:COG4235     96 FQQGDYAEAIAAWQKLL 112
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 266-345 4.49e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.51  E-value: 4.49e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  266 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 345
Cdd:COG5010     73 SLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 282-377 5.74e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.97  E-value: 5.74e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  282 QSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYES 361
Cdd:COG4783      5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                           90
                   ....*....|....*.
gi 2462632128  362 CNQPQDAIKCYLNAAR 377
Cdd:COG4783     85 AGDYDEALALLEKALK 100
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 266-378 2.01e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.58  E-value: 2.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  266 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 345
Cdd:COG5010     39 EDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALS 118

                           90       100       110
                   ....*....|....*....|....*....|...
gi 2462632128  346 HGHAAAWMDLGTLYESCNQPQDAIKCYLNAARS 378
Cdd:COG5010    119 PDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 201-316 2.29e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.86  E-value: 2.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  201 NAEIQFHIAHLYETQRKYHSAKEAYEQLLQTEnlPAqvKATVLQQLGWMhhnmdLVGDKATKEsyAIQYLQKSLEADPNS 280
Cdd:COG4235     16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--PD--NADALLDLAEA-----LLAAGDTEE--AEELLERALALDPDN 84

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 2462632128  281 GQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASAD 316
Cdd:COG4235     85 PEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
290-377 5.12e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.71  E-value: 5.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  290 CYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQaYICAVQLDHGHAAAWMDLGTLYESCNQPQDAI 369
Cdd:COG3063      1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                   ....*...
gi 2462632128  370 KCYLNAAR 377
Cdd:COG3063     80 AYLERALE 87
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 283-397 7.45e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.12  E-value: 7.45e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  283 SWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESC 362
Cdd:COG2956     10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 2462632128  363 NQPQDAIKCYLNAARSKRcSNTSTLAARIKFLQAQ 397
Cdd:COG2956     90 GLLDRAEELLEKLLELDP-DDAEALRLLAEIYEQE 123
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 84-419 9.53e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 56.63  E-value: 9.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   84 AEGKVESD--FFCQLGHFNLLLEDYSKALSAYQRYYSLQAdywKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFC 161
Cdd:TIGR02917  355 ALGLDPDDpaALSLLGEAYLALGDFEKAAEYLAKATELDP---ENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELG 431

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  162 RAKEI----HLRLGLMFKVNTDYKSSLKHfqlalidcnpcTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTEnlPAQ 237
Cdd:TIGR02917  432 RADLLlilsYLRSGQFDKALAAAKKLEKK-----------QPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIE--PDF 498

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  238 VKATVLQQlgwmhhNMDLVGDKATKesyAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADT 317
Cdd:TIGR02917  499 FPAAANLA------RIDIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEP 569

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  318 WCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAArsKRCSNTSTLAARIKFLQAq 397
Cdd:TIGR02917  570 ALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLL--ALQPDSALALLLLADAYA- 646

                          330       340
                   ....*....|....*....|..
gi 2462632128  398 lcnlpqsSLQNKTKLLPSIEEA 419
Cdd:TIGR02917  647 -------VMKNYAKAITSLKRA 661
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 72-191 3.83e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.58  E-value: 3.83e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   72 KAVRCYESLIlkAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQ 151
Cdd:COG4783     22 EAEALLEKAL--ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD---EPEARLNLGLALLKAGDYDEALALLE 96

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 2462632128  152 DVLYVDPSFcraKEIHLRLGLMFKVNTDYKSSLKHFQLAL 191
Cdd:COG4783     97 KALKLDPEH---PEAYLRLARAYRALGRPDEAIAALEKAL 133
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 266-338 3.66e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.91  E-value: 3.66e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462632128  266 AIQYLQKSLEADPNS---GQSWYFLGRCYSSIGKVQDAFISYRQSID---KSEASADTWCSIGVLYQQQNQPMDALQAY 338
Cdd:COG1729     12 AIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKrypDSPKAPDALLKLGLSYLELGDYDKARATL 90
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 127-280 4.28e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.49  E-value: 4.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  127 AAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAkeiHLRLGLMFKVNTDYKSSLKHFQLALIDcNPctlSNAEIQF 206
Cdd:COG4783      4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEA---FALLGEILLQLGDLDEAIVLLHEALEL-DP---DEPEARL 76

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462632128  207 HIAHLYETQRKYHSAKEAYEQLLQTEnlPAQvkATVLQQLGWMHHNMdlvGDKAtkesYAIQYLQKSLEADPNS 280
Cdd:COG4783     77 NLGLALLKAGDYDEALALLEKALKLD--PEH--PEAYLRLARAYRAL---GRPD----EAIAALEKALELDPDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 108-278 7.23e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.26  E-value: 7.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  108 KALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGlmfkvntDYKSSLKHF 187
Cdd:COG5010      5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLG-------DFEESLALL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  188 QLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTEnlPAQVKAtvlqqlgwmHHNMDLVGDKATKESYAI 267
Cdd:COG5010     78 EQAL-QLDP---NNPELYYNLALLYSRSGDKDEAKEYYEKALALS--PDNPNA---------YSNLAALLLSLGQDDEAK 142

                          170
                   ....*....|.
gi 2462632128  268 QYLQKSLEADP 278
Cdd:COG5010    143 AALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 100-234 1.46e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.49  E-value: 1.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  100 NLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHW------AIKAFQDVLYVDPSFcraKEIHLRLGLM 173
Cdd:COG5010     21 RTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKlgdfeeSLALLEQALQLDPNN---PELYYNLALL 97

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462632128  174 FKVNTDYKSSLKHFQLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENL 234
Cdd:COG5010     98 YSRSGDKDEAKEYYEKAL-ALSP---DNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 108-246 2.83e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.00  E-value: 2.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  108 KALSAYQRYysLQADYwKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFcraKEIHLRLGLMFKVNTDYKSSLKHF 187
Cdd:COG4235      1 EAIARLRQA--LAANP-NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN---ADALLDLAEALLAAGDTEEAEELL 74

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462632128  188 QLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLqtENLPAQVKATVLQQL 246
Cdd:COG4235     75 ERAL-ALDP---DNPEALYLLGLAAFQQGDYAEAIAAWQKLL--ALLPADAPARLLEAS 127
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 162-372 2.91e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 2.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  162 RAKEIHLRLGLMFKVNTDYKSSLKHFQlALIDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTE--NLPAQVk 239
Cdd:TIGR02917  599 DSPEAWLMLGRAQLAAGDLNKAVSSFK-KLLALQP---DSALALLLLADAYAVMKNYAKAITSLKRALELKpdNTEAQI- 673

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  240 atVLQQLgwmhhnmdLVGDKATKESYAI-QYLQKsleADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIdKSEASADTW 318
Cdd:TIGR02917  674 --GLAQL--------LLAAKRTESAKKIaKSLQK---QHPKAALGFELEGDLYLRQKDYPAAIQAYRKAL-KRAPSSQNA 739

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462632128  319 CSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCY 372
Cdd:TIGR02917  740 IKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHY 793
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 82-317 8.77e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 8.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   82 LKAEGKVESDFF-CQLGHFNLLLEDySKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSF 160
Cdd:TIGR02917  658 LKRALELKPDNTeAQIGLAQLLLAA-KRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSS 736

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  161 CRAKEIHLRLGLmfkvNTDYKSSLKHFQLALIDcNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTenlpAQVKA 240
Cdd:TIGR02917  737 QNAIKLHRALLA----SGNTAEAVKTLEAWLKT-HP---NDAVLRTALAELYLAQKDYDKAIKHYQTVVKK----APDNA 804

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462632128  241 TVLQQLGWMHHNMdlvgdkatKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADT 317
Cdd:TIGR02917  805 VVLNNLAWLYLEL--------KDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAI 873
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 105-372 8.92e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 8.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  105 DYSKALSAYQRYYSLQADYWkNAAFLygLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKE----IHLRLGLMfkvnTDY 180
Cdd:TIGR02917  276 NYEDARETLQDALKSAPEYL-PALLL--AGASEYQLGNLEQAYQYLNQILKYAPNSHQARRllasIQLRLGRV----DEA 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  181 KSSLKHFqLALIDCNPCTLSNAEIqfhiAHLyeTQRKYHSAKEAYEQLlqTENLPAQVKATVLQQLGWMHHNmdlvgdka 260
Cdd:TIGR02917  349 IATLSPA-LGLDPDDPAALSLLGE----AYL--ALGDFEKAAEYLAKA--TELDPENAAARTQLGISKLSQG-------- 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  261 tKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYIC 340
Cdd:TIGR02917  412 -DPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEK 490

                          250       260       270
                   ....*....|....*....|....*....|..
gi 2462632128  341 AVQLDHGHAAAWMDLGTLYESCNQPQDAIKCY 372
Cdd:TIGR02917  491 ALSIEPDFFPAAANLARIDIQEGNPDDAIQRF 522
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 72-158 9.80e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 9.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   72 KAVRCYESLILKAEGkvESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQ 151
Cdd:COG5010     72 ESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAALQ 146


                   ....*..
gi 2462632128  152 DVLYVDP 158
Cdd:COG5010    147 RALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
136-230 1.10e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.08  E-value: 1.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  136 VYFYYNAFHWAIKAFQDVLYVDPSFCRAkeiHLRLGLMFKVNTDYKSSLKhFQLALiDCNPctlSNAEIQFHIAHLYETQ 215
Cdd:COG3063      1 LYLKLGDLEEAEEYYEKALELDPDNADA---LNNLGLLLLEQGRYDEAIA-LEKAL-KLDP---NNAEALLNLAELLLEL 72

                           90
                   ....*....|....*
gi 2462632128  216 RKYHSAKEAYEQLLQ 230
Cdd:COG3063     73 GDYDEALAYLERALE 87
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 105-191 2.22e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.90  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  105 DYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSL 184
Cdd:COG1729      8 DYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDKAR 87


                   ....*..
gi 2462632128  185 KHFQLAL 191
Cdd:COG1729     88 ATLEELI 94
TPR COG0790
TPR repeat [General function prediction only];
202-377 3.30e-04

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 43.76  E-value: 3.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  202 AEIQFHIAHLYE----TQRKYHSAKEAYEQLLQTENLPAQVkatvlqQLGWMHHNmdlvGdKATKESY--AIQYLQKSle 275
Cdd:COG0790     63 AEAQYNLGLMYAegrgVPKDYEKALEWFEKAAEQGDAEAQY------NLGLMYEE----G-LGVPQDYakALEWYEKA-- 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  276 ADPNSGQSWYFLGRCYSS-IGKVQD---AFISYRQSIDKSEASADTwcSIGVLYQQ-QNQPMD---ALQAYICAVqlDHG 347
Cdd:COG0790    130 AEQGDADAQYNLGLLYLNgEGVPKDpakAAEWYRKAAEQGDADAQY--NLGVLYENgRGVPKDpakALEWYRKAA--EQG 205

                          170       180       190
                   ....*....|....*....|....*....|....
gi 2462632128  348 HAAAWMDLGTLYESCNQ-PQD---AIKCYLNAAR 377
Cdd:COG0790    206 DADAQYNLGRLYLNGEGvEKDlekALRWLRKAAE 239
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 146-231 3.67e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 3.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  146 AIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQlALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAY 225
Cdd:COG1729     12 AIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFE-KLLKRYPDSPKAPDALLKLGLSYLELGDYDKARATL 90


                   ....*.
gi 2462632128  226 EQLLQT 231
Cdd:COG1729     91 EELIKK 96
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
93-163 4.23e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.98  E-value: 4.23e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462632128   93 FCQLGHFNLLLEDYSKALSAYQRYYSLQADYwknAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRA 163
Cdd:COG4785    110 YNNRGLAYLLLGDYDAALEDFDRALELDPDY---AYAYLNRGIALYYLGRYELAIADLEKALELDPNDPER 177
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 201-347 7.33e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 42.98  E-value: 7.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  201 NAEIQFHIAHLYETQRKYHSAKEAYEQLLQtenlpAQVKATVLQQLGwmhhnmDLVGDKATKesyAIQYLQKSLEADPNS 280
Cdd:COG3071    192 DPELAAAYARALIALGDHDEAERLLREALK-----RQWDPRLVRLYG------RLQGGDPAK---QLKRAEKWLKKHPND 257

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  281 GQSWYFLGR-CYSS--IGKVQDAFisyRQSIdKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHG 347
Cdd:COG3071    258 PDLLLALGRlCLRNqlWGKAREYL---EAAL-ALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 179-280 1.04e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.97  E-value: 1.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  179 DYKSSLKHFQlALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTEnlPAQVKA-TVLQQLGWMHHNMdlvG 257
Cdd:COG1729      8 DYDEAIAAFK-AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY--PDSPKApDALLKLGLSYLEL---G 81

                           90       100
                   ....*....|....*....|...
gi 2462632128  258 DKATkesyAIQYLQKSLEADPNS 280
Cdd:COG1729     82 DYDK----ARATLEELIKKYPDS 100
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
101-191 1.31e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  101 LLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIkAFQDVLYVDPSFCRAkeiHLRLGLMFKVNTDY 180
Cdd:COG3063      3 LKLGDLEEAEEYYEKALELDPD---NADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEA---LLNLAELLLELGDY 75

                           90
                   ....*....|.
gi 2462632128  181 KSSLKHFQLAL 191
Cdd:COG3063     76 DEALAYLERAL 86
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 215-310 2.12e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.20  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  215 QRKYHSAKEAYEQLLQtENLPAQVKATVLQQLGWMHHNMdlvGDKATkesyAIQYLQKSLEADPNS---GQSWYFLGRCY 291
Cdd:COG1729      6 AGDYDEAIAAFKAFLK-RYPNSPLAPDALYWLGEAYYAL---GDYDE----AAEAFEKLLKRYPDSpkaPDALLKLGLSY 77

                           90
                   ....*....|....*....
gi 2462632128  292 SSIGKVQDAFISYRQSIDK 310
Cdd:COG1729     78 LELGDYDKARATLEELIKK 96
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
166-279 2.42e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 2.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  166 IHLRLGlmfkvntDYKSSLKHFQLALiDCNPctlSNAEIQFHIAHLYETQRKYHSAkEAYEQLLQTEnlPAQVKAtvLQQ 245
Cdd:COG3063      1 LYLKLG-------DLEEAEEYYEKAL-ELDP---DNADALNNLGLLLLEQGRYDEA-IALEKALKLD--PNNAEA--LLN 64

                           90       100       110
                   ....*....|....*....|....*....|....
gi 2462632128  246 LGWMHHNMdlvGDKATkesyAIQYLQKSLEADPN 279
Cdd:COG3063     65 LAELLLEL---GDYDE----ALAYLERALELDPS 91
TPR COG0790
TPR repeat [General function prediction only];
215-377 3.29e-03

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 40.68  E-value: 3.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  215 QRKYHSAKEAYEQLLQTENLPAQVkatvlqQLGWMHHNMDLVgDKATKEsyAIQYLQKSleADPNSGQSWYFLGRCYSS- 293
Cdd:COG0790     44 AAGAAAAAAAAAAAAAAGGAEAQY------NLGLMYAEGRGV-PKDYEK--ALEWFEKA--AEQGDAEAQYNLGLMYEEg 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  294 IGKVQD---AFISYRQSIDKSEASAdtWCSIGVLYQQ-QNQPMDALQA---YICAVqlDHGHAAAWMDLGTLYES---CN 363
Cdd:COG0790    113 LGVPQDyakALEWYEKAAEQGDADA--QYNLGLLYLNgEGVPKDPAKAaewYRKAA--EQGDADAQYNLGVLYENgrgVP 188

                          170
                   ....*....|....*
gi 2462632128  364 Q-PQDAIKCYLNAAR 377
Cdd:COG0790    189 KdPAKALEWYRKAAE 203
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
72-162 3.82e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 3.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   72 KAVRCYESLILKAEGkvESDFFCQLGHFNLLLEDYSKALsAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKAFQ 151
Cdd:COG3063     10 EAEEYYEKALELDPD--NADALNNLGLLLLEQGRYDEAI-ALEKALKLDPN---NAEALLNLAELLLELGDYDEALAYLE 83

                           90
                   ....*....|.
gi 2462632128  152 DVLYVDPSFCR 162
Cdd:COG3063     84 RALELDPSALR 94
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 133-317 3.86e-03

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 40.40  E-value: 3.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  133 LGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAkeiHLRLGLMFKVNTDYKSSLKHFQLALidcnpcTLSNAEIQFHI---A 209
Cdd:TIGR02521   37 LALGYLEQGDLEVAKENLDKALEHDPDDYLA---YLALALYYQQLGELEKAEDSFRRAL------TLNPNNGDVLNnygT 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  210 HLYEtQRKYHSAKEAYEQLLQTENLPAQVKAtvlqqlgwmHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGR 289
Cdd:TIGR02521  108 FLCQ-QGKYEQAMQQFEQAIEDPLYPQPARS---------LENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAE 177

                          170       180
                   ....*....|....*....|....*...
gi 2462632128  290 CYSSIGKVQDAFISYRQSIDKSEASADT 317
Cdd:TIGR02521  178 LYYLRGQYKDARAYLERYQQTYNQTAES 205
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 70-238 4.09e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.13  E-value: 4.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128   70 LGKAVRCYESLILKAEGKVEsdFFCQLGHFNLLLEDYSKALSAYQRYYSLQADywkNAAFLYGLGLVYFYYNAFHWAIKA 149
Cdd:COG3914    128 LEEALAALRRALALNPDFAE--AYLNLGEALRRLGRLEEAIAALRRALELDPD---NAEALNNLGNALQDLGRLEEAIAA 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462632128  150 FQDVLYVDPSFCRAkeIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTLSNaeiqFHIAHLY----ETQRKYHsakEAY 225
Cdd:COG3914    203 YRRALELDPDNADA--HSNLLFALRQACDWEVYDRFEELLAALARGPSELSP----FALLYLPdddpAELLALA---RAW 273

                          170
                   ....*....|...
gi 2462632128  226 EQLLQTENLPAQV 238
Cdd:COG3914    274 AQLVAAAAAPELP 286
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 167-231 4.34e-03

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 40.80  E-value: 4.34e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462632128  167 HLRLGLMFK-VNTDYKSSLKHFQLALIDCNPCTLS--NAE---IQFHIAHLYEtqrKYHSAKEAYEQLLQT 231
Cdd:cd24145     10 ILRKALYYEsDKPDPQKALKYYKEALEQADELGMDpfSDEvtgIRIKIAEMLE---KLGMYKAAYEVLERL 77
TPR_1 pfam00515
Tetratricopeptide repeat;
127-160 5.15e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 5.15e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2462632128  127 AAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSF 160
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_17 pfam13431
Tetratricopeptide repeat;
269-300 7.96e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 35.21  E-value: 7.96e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2462632128  269 YLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA 300
Cdd:pfam13431    1 LYLKALELDPNNADAYYNLAVLLLELGQSETA 32
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 312-377 8.46e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 8.46e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462632128  312 EASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAAR 377
Cdd:COG4783      1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALE 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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