|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
84-196 |
3.70e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription]; :
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 80.75 E-value: 3.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 84 SLGNfgvhLPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLE 163
Cdd:COG4886 200 PLGN----LTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLK 275
|
90 100 110
....*....|....*....|....*....|...
gi 2462490166 164 VLDLEGNSVEDLgQVRYLQLCPRLAMLTLEGNL 196
Cdd:COG4886 276 TLDLSNNQLTDL-KLKELELLLGLNSLLLLLLL 307
|
|
| PABP-1234 super family |
cl31127 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
315-483 |
3.02e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range. The actual alignment was detected with superfamily member TIGR01628:
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 43.64 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 315 PEDNTSSLTHGAGQVLCGNPTK-GLRERRHQ---------CQAREPPEQLPQHRP-----GDPAASTSTPepdpadssdf 379
Cdd:TIGR01628 336 PEEANRAVTEMHGRMLGGKPLYvALAQRKEQrrahlqdqfMQLQPRMRQLPMGSPmggamGQPPYYGQGP---------- 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 380 LALAGLRAWREHGVRPLPYRHPESQQEGAV--APWGPRRVPEEQVHQAEPKTPSSPpslASEPSGTSSQHLVPSPPKHPR 457
Cdd:TIGR01628 406 QQQFNGQPLGWPRMSMMPTPMGPGGPLRPNglAPMNAVRAPSRNAQNAAQKPPMQP---VMYPPNYQSLPLSQDLPQPQS 482
|
170 180
....*....|....*....|....*...
gi 2462490166 458 PRDSGSSSPRWSTDLQSR--GRRLRVLG 483
Cdd:TIGR01628 483 TASQGGQNKKLAQVLASAtpQMQKQVLG 510
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
84-196 |
3.70e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 80.75 E-value: 3.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 84 SLGNfgvhLPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLE 163
Cdd:COG4886 200 PLGN----LTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLK 275
|
90 100 110
....*....|....*....|....*....|...
gi 2462490166 164 VLDLEGNSVEDLgQVRYLQLCPRLAMLTLEGNL 196
Cdd:COG4886 276 TLDLSNNQLTDL-KLKELELLLGLNSLLLLLLL 307
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
91-233 |
1.23e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 73.28 E-value: 1.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 91 HLPNLDQLKLNGSHLGSLRDLGtSLGHLQVLWLARCGLADLDGIASLPALKELY-------------------------- 144
Cdd:cd21340 44 FLTNLTHLYLQNNQIEKIENLE-NLVNLKKLYLGGNRISVVEGLENLTNLEELHienqrlppgekltfdprslaalsnsl 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 145 ----ASYNNISDLSPLCLLEQLEVLDLEGNSVEDLGQV-RYLQLCPRLAMLTLEGNLVCLQPapgptnkvprgyNYRAEV 219
Cdd:cd21340 123 rvlnISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELlDLLSSWPSLRELDLTGNPVCKKP------------KYRDKI 190
|
170
....*....|....
gi 2462490166 220 RKLIPQLQVLDEVP 233
Cdd:cd21340 191 ILASKSLEVLDGKE 204
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
117-156 |
1.08e-06 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 45.31 E-value: 1.08e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 2462490166 117 HLQVLWLARCGLADLDGIASLPALKELYASYNN-ISDLSPL 156
Cdd:pfam12799 2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNNkITDLSDL 42
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
315-483 |
3.02e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 43.64 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 315 PEDNTSSLTHGAGQVLCGNPTK-GLRERRHQ---------CQAREPPEQLPQHRP-----GDPAASTSTPepdpadssdf 379
Cdd:TIGR01628 336 PEEANRAVTEMHGRMLGGKPLYvALAQRKEQrrahlqdqfMQLQPRMRQLPMGSPmggamGQPPYYGQGP---------- 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 380 LALAGLRAWREHGVRPLPYRHPESQQEGAV--APWGPRRVPEEQVHQAEPKTPSSPpslASEPSGTSSQHLVPSPPKHPR 457
Cdd:TIGR01628 406 QQQFNGQPLGWPRMSMMPTPMGPGGPLRPNglAPMNAVRAPSRNAQNAAQKPPMQP---VMYPPNYQSLPLSQDLPQPQS 482
|
170 180
....*....|....*....|....*...
gi 2462490166 458 PRDSGSSSPRWSTDLQSR--GRRLRVLG 483
Cdd:TIGR01628 483 TASQGGQNKKLAQVLASAtpQMQKQVLG 510
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
201-466 |
3.68e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.77 E-value: 3.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 201 PAPGPTNKVPRGYNYRAEVRKLIPQLqvldeVPAAHTGPPAPPRL-----SQDWLAVKEAIKKGNGLPPLDCP----RGA 271
Cdd:PHA03247 2494 AAPDPGGGGPPDPDAPPAPSRLAPAI-----LPDEPVGEPVHPRMltwirGLEELASDDAGDPPPPLPPAAPPaapdRSV 2568
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 272 PIRRLDPELSLPETQSRASRP----------------WPFSLLVHGGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPT 335
Cdd:PHA03247 2569 PPPRPAPRPSEPAVTSRARRPdappqsarprapvddrGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPP 2648
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 336 KGL-----------RERRHQCQAREPPEQLPQHRP---------------GDPAASTSTPEPDPADSSDFLALAGLRAWR 389
Cdd:PHA03247 2649 PERprddpapgrvsRPRRARRLGRAAQASSPPQRPrrraarptvgsltslADPPPPPPTPEPAPHALVSATPLPPGPAAA 2728
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 390 EHGVRPLPYRH-PESQQEGAVAPWGPRRVPEEQVHQAEPKT------PSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSG 462
Cdd:PHA03247 2729 RQASPALPAAPaPPAVPAGPATPGGPARPARPPTTAGPPAPappaapAAGPPRRLTRPAVASLSESRESLPSPWDPADPP 2808
|
....
gi 2462490166 463 SSSP 466
Cdd:PHA03247 2809 AAVL 2812
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
84-196 |
3.70e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 80.75 E-value: 3.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 84 SLGNfgvhLPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLE 163
Cdd:COG4886 200 PLGN----LTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLK 275
|
90 100 110
....*....|....*....|....*....|...
gi 2462490166 164 VLDLEGNSVEDLgQVRYLQLCPRLAMLTLEGNL 196
Cdd:COG4886 276 TLDLSNNQLTDL-KLKELELLLGLNSLLLLLLL 307
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
91-195 |
1.97e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 78.44 E-value: 1.97e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 91 HLPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADL-DGIASLPALKELYASYNNISDLS-PLCLLEQLEVLDLE 168
Cdd:COG4886 134 NLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLS 213
|
90 100
....*....|....*....|....*..
gi 2462490166 169 GNSVEDLGQVryLQLCPRLAMLTLEGN 195
Cdd:COG4886 214 GNQLTDLPEP--LANLTNLETLDLSNN 238
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
91-233 |
1.23e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 73.28 E-value: 1.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 91 HLPNLDQLKLNGSHLGSLRDLGtSLGHLQVLWLARCGLADLDGIASLPALKELY-------------------------- 144
Cdd:cd21340 44 FLTNLTHLYLQNNQIEKIENLE-NLVNLKKLYLGGNRISVVEGLENLTNLEELHienqrlppgekltfdprslaalsnsl 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 145 ----ASYNNISDLSPLCLLEQLEVLDLEGNSVEDLGQV-RYLQLCPRLAMLTLEGNLVCLQPapgptnkvprgyNYRAEV 219
Cdd:cd21340 123 rvlnISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELlDLLSSWPSLRELDLTGNPVCKKP------------KYRDKI 190
|
170
....*....|....
gi 2462490166 220 RKLIPQLQVLDEVP 233
Cdd:cd21340 191 ILASKSLEVLDGKE 204
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
47-195 |
7.04e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 70.35 E-value: 7.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 47 EQLVEEYLSPARLQALARVDDLRLVRTLEMCVDTREGSLGNFGVHLPNLDQLKLNGShlgslrDLGTSLGHLQVLWLARC 126
Cdd:COG4886 50 TLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGN 123
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462490166 127 GLADL-DGIASLPALKELYASYNNISDL-SPLCLLEQLEVLDLEGNSVEDLGQVryLQLCPRLAMLTLEGN 195
Cdd:COG4886 124 QLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLPEE--LGNLTNLKELDLSNN 192
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
117-156 |
1.08e-06 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 45.31 E-value: 1.08e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 2462490166 117 HLQVLWLARCGLADLDGIASLPALKELYASYNN-ISDLSPL 156
Cdd:pfam12799 2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNNkITDLSDL 42
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
138-170 |
1.41e-06 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 44.93 E-value: 1.41e-06
10 20 30
....*....|....*....|....*....|...
gi 2462490166 138 PALKELYASYNNISDLSPLCLLEQLEVLDLEGN 170
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGN 33
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
117-170 |
2.24e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.82 E-value: 2.24e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462490166 117 HLQVLWLARCGLADLDGIA--SLPALKELYASYNNISDLSPLCL--LEQLEVLDLEGN 170
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAfkGLSNLKVLDLSNNLLTTLSPGAFsgLPSLRYLDLSGN 59
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
315-483 |
3.02e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 43.64 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 315 PEDNTSSLTHGAGQVLCGNPTK-GLRERRHQ---------CQAREPPEQLPQHRP-----GDPAASTSTPepdpadssdf 379
Cdd:TIGR01628 336 PEEANRAVTEMHGRMLGGKPLYvALAQRKEQrrahlqdqfMQLQPRMRQLPMGSPmggamGQPPYYGQGP---------- 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 380 LALAGLRAWREHGVRPLPYRHPESQQEGAV--APWGPRRVPEEQVHQAEPKTPSSPpslASEPSGTSSQHLVPSPPKHPR 457
Cdd:TIGR01628 406 QQQFNGQPLGWPRMSMMPTPMGPGGPLRPNglAPMNAVRAPSRNAQNAAQKPPMQP---VMYPPNYQSLPLSQDLPQPQS 482
|
170 180
....*....|....*....|....*...
gi 2462490166 458 PRDSGSSSPRWSTDLQSR--GRRLRVLG 483
Cdd:TIGR01628 483 TASQGGQNKKLAQVLASAtpQMQKQVLG 510
|
|
| LRR_9 |
pfam14580 |
Leucine-rich repeat; |
97-230 |
3.25e-04 |
|
Leucine-rich repeat;
Pssm-ID: 405295 [Multi-domain] Cd Length: 175 Bit Score: 41.67 E-value: 3.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 97 QLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDLSPlcLLEQ----LEVLDLEGNSV 172
Cdd:pfam14580 23 ELDLRGYKIPIIENLGATLDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIGE--GLGEalpnLTELILTNNNL 100
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462490166 173 EDLGQVRYLQLCPRLAMLTLEGNLVCLQPapgptnkvprgyNYRAEVRKLIPQLQVLD 230
Cdd:pfam14580 101 QELGDLDPLASLKKLTFLSLLRNPVTNKP------------HYRLYVIYKVPQLRLLD 146
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
201-466 |
3.68e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.77 E-value: 3.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 201 PAPGPTNKVPRGYNYRAEVRKLIPQLqvldeVPAAHTGPPAPPRL-----SQDWLAVKEAIKKGNGLPPLDCP----RGA 271
Cdd:PHA03247 2494 AAPDPGGGGPPDPDAPPAPSRLAPAI-----LPDEPVGEPVHPRMltwirGLEELASDDAGDPPPPLPPAAPPaapdRSV 2568
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 272 PIRRLDPELSLPETQSRASRP----------------WPFSLLVHGGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPT 335
Cdd:PHA03247 2569 PPPRPAPRPSEPAVTSRARRPdappqsarprapvddrGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPP 2648
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 336 KGL-----------RERRHQCQAREPPEQLPQHRP---------------GDPAASTSTPEPDPADSSDFLALAGLRAWR 389
Cdd:PHA03247 2649 PERprddpapgrvsRPRRARRLGRAAQASSPPQRPrrraarptvgsltslADPPPPPPTPEPAPHALVSATPLPPGPAAA 2728
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 390 EHGVRPLPYRH-PESQQEGAVAPWGPRRVPEEQVHQAEPKT------PSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSG 462
Cdd:PHA03247 2729 RQASPALPAAPaPPAVPAGPATPGGPARPARPPTTAGPPAPappaapAAGPPRRLTRPAVASLSESRESLPSPWDPADPP 2808
|
....
gi 2462490166 463 SSSP 466
Cdd:PHA03247 2809 AAVL 2812
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
54-186 |
5.54e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 42.34 E-value: 5.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 54 LSPARLQALArvDDLRLVRTLEMcVDTREGSLGNFGV--------HLPNLDQLKLNGShlgSLRDLG--------TSLGH 117
Cdd:cd00116 149 LEGASCEALA--KALRANRDLKE-LNLANNGIGDAGIralaeglkANCNLEVLDLNNN---GLTDEGasalaetlASLKS 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 118 LQVLWLARCGLADLdGIASL--------PALKELYASYNNISDLSPLCLLE------QLEVLDLEGNSV--EDLGQVRYL 181
Cdd:cd00116 223 LEVLNLGDNNLTDA-GAAALasallspnISLLTLSLSCNDITDDGAKDLAEvlaekeSLLELDLRGNKFgeEGAQLLAES 301
|
....*
gi 2462490166 182 QLCPR 186
Cdd:cd00116 302 LLEPG 306
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
138-197 |
5.61e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.27 E-value: 5.61e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462490166 138 PALKELYASYNNISDLSPLCL--LEQLEVLDLEGNSVEDLGQvRYLQLCPRLAMLTLEGNLV 197
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFkgLSNLKVLDLSNNLLTTLSP-GAFSGLPSLRYLDLSGNRL 61
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
201-501 |
2.72e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 40.69 E-value: 2.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 201 PAPGPTNKVPRGYNYRAEvrkliPQLQVLDEVPAAHTGPPAPPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPEL 280
Cdd:PHA03247 2742 PAVPAGPATPGGPARPAR-----PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA 2816
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 281 SLPETQSRAS-RPWPFSLLVHGGPLPEGLLSEDLAPEdntsslthgaGQVLCGNPTkglrerrhqcqAREPPeqlpqhrP 359
Cdd:PHA03247 2817 ALPPAASPAGpLPPPTSAQPTAPPPPPGPPPPSLPLG----------GSVAPGGDV-----------RRRPP-------S 2868
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 360 GDPAASTSTPEPDPADSSdflalaglrawrehgVRPLPYRHPESQqegavapwgprrvPEEQVHQAEPKTPSSPPSLASE 439
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRL---------------ARPAVSRSTESF-------------ALPPDQPERPPQPQAPPPPQPQ 2920
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462490166 440 PSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGrrlRVLGSWGPGLGDGVAAVPVLRA 501
Cdd:PHA03247 2921 PQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG---AVPQPWLGALVPGRVAVPRFRV 2979
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
346-513 |
8.82e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 38.81 E-value: 8.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 346 QAREPPEQLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQA 425
Cdd:PRK07764 611 EAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAP 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 426 EPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVA 505
Cdd:PRK07764 691 AAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAP 770
|
....*...
gi 2462490166 506 SGLSPRAQ 513
Cdd:PRK07764 771 AAAPPPSP 778
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
231-444 |
9.84e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 38.65 E-value: 9.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 231 EVPAAHTGP--PAPPRLSQDWLAVKEAIKKGNGLPPLDcprGAPIRRldpelslPETQSRASRPWPfsllvhgGPLPEGl 308
Cdd:PRK14086 100 PHARRTSEPelPRPGRRPYEGYGGPRADDRPPGLPRQD---QLPTAR-------PAYPAYQQRPEP-------GAWPRA- 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462490166 309 lSEDLAPEDNTSSLTHGAgqvlcgNPTKGLRERRHQCQAREPP-EQLPQHRPGDPAASTSTPEPDPAdssdflalaglRA 387
Cdd:PRK14086 162 -ADDYGWQQQRLGFPPRA------PYASPASYAPEQERDREPYdAGRPEYDQRRRDYDHPRPDWDRP-----------RR 223
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462490166 388 WRehgvRPLPYRHPESQQEGAVAPWGPRRVPEEQvhqaEPKTPSSPPSLASEPSGTS 444
Cdd:PRK14086 224 DR----TDRPEPPPGAGHVHRGGPGPPERDDAPV----VPIRPSAPGPLAAQPAPAP 272
|
|
|