|
Name |
Accession |
Description |
Interval |
E-value |
| BRCT_MDC1_rpt2 |
cd18441 |
second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; ... |
1825-1905 |
1.64e-43 |
|
second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the second BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is not conserved in this family.
Pssm-ID: 349394 Cd Length: 81 Bit Score: 152.92 E-value: 1.64e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1825 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEA 1904
Cdd:cd18441 1 LLEGYEIHVTPGVKPEPPQMKDIITCAGGTFLPSMPKTYKPQTVVISCPEDFPHCSPALKAGLPVVSAEFLLTGILRQEA 80
|
.
gi 2462492661 1905 K 1905
Cdd:cd18441 81 D 81
|
|
| FHA_MDC1 |
cd22665 |
forkhead associated (FHA) domain found in mediator of DNA damage checkpoint protein 1 (MDC1) ... |
53-152 |
1.03e-37 |
|
forkhead associated (FHA) domain found in mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also called nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438717 [Multi-domain] Cd Length: 97 Bit Score: 136.98 E-value: 1.03e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 53 GRLHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAwdKAPILRDCGSLNGTQIlRPPKVLSPGV 132
Cdd:cd22665 1 GRLKVFSQAHGPEKDFPLYEGENVIGRDPSCSVVLPDKSVSKQHACIEVDG--GTHLIEDLGSTNGTRI-GNKVRLKPNV 77
|
90 100
....*....|....*....|
gi 2462492661 133 SHRLRDQELILFADLLCQYH 152
Cdd:cd22665 78 RYELIDGDLLLFGDVKCQYV 97
|
|
| BRCT_MDC1_rpt1 |
cd17744 |
first BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; ... |
1723-1793 |
1.92e-27 |
|
first BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the first BRCT domain.
Pssm-ID: 349375 [Multi-domain] Cd Length: 72 Bit Score: 106.93 E-value: 1.92e-27
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462492661 1723 PKVLFTGVVD-ARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1793
Cdd:cd17744 1 PRVLFTGVSDkEEGEKIIKKLGGSVVDSVEDCTHLVTDKVRRTVKFLCALARGIPIVSPDWLEASIKANKFL 72
|
|
| BRCT_PAXIP1_rpt6_like |
cd18432 |
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1), second BRCT domain of mediator of DNA ... |
1825-1903 |
1.39e-26 |
|
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1), second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the sixth BRCT domain of PAXIP1 and the second BRCT domain of MDC1.
Pssm-ID: 349385 [Multi-domain] Cd Length: 85 Bit Score: 104.97 E-value: 1.39e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1825 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMP----RSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVL 1900
Cdd:cd18432 1 LFEGYTFYVTPNVKPPPEELKEIIEAAGGKVLKKLPtkriEDDDPDTIVISCEEDRKLWKPLKKKGIPIYSVEFILTGIL 80
|
...
gi 2462492661 1901 KQE 1903
Cdd:cd18432 81 RQK 83
|
|
| BRCT_PAXIP1_rpt5 |
cd17712 |
fifth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also ... |
1722-1793 |
1.81e-20 |
|
fifth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. This family corresponds to the fifth BRCT domain.
Pssm-ID: 349344 Cd Length: 75 Bit Score: 86.91 E-value: 1.81e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462492661 1722 APKVLFTGVVDARGER---AVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1793
Cdd:cd17712 1 TPRVLFTGFDPVQVRKltkKVTILGGEVVESPQECTHLVAPKVSRTVKFLTAISVCKHIVTPEWLEESFKQGKFL 75
|
|
| BRCT_PAXIP1_rpt6 |
cd18440 |
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also ... |
1825-1903 |
8.13e-20 |
|
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. This family corresponds to the sixth BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is not conserved in this family.
Pssm-ID: 349393 Cd Length: 90 Bit Score: 85.73 E-value: 8.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1825 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSmPRSYKPQR----------VVITCPQDFPHCSIPLRVGLPLLSPEF 1894
Cdd:cd18440 1 LFKGKYFYITPGVKPSPSVLKEIIESAGGKVEKK-RPSLKKIMeknnqgppsyIIITCENDLHLCRDLFRKNIDVYNAEF 79
|
....*....
gi 2462492661 1895 LLTGVLKQE 1903
Cdd:cd18440 80 ILTGVLRQK 88
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1057-1587 |
1.06e-17 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 90.38 E-value: 1.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1057 ATRGRKNRSSVKTPEPVVPTAP-ELQPSTSTDQPVtSEPTYQAT----RGRKNRSSVKTPEPVVPTAPELRPSTsTDRPV 1131
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPsRLAPAILPDEPV-GEPVHPRMltwiRGLEELASDDAGDPPPPLPPAAPPAA-PDRSV 2568
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1132 -TPKPTSRttrsrtnmssvktpetvvPTAPELQiSTSTDQPVTPKPTsrttRSRTNMSSVKNPESTVPIAPeLPPSTSTE 1210
Cdd:PHA03247 2569 pPPRPAPR------------------PSEPAVT-SRARRPDAPPQSA----RPRAPVDDRGDPRGPAPPSP-LPPDTHAP 2624
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1211 QPVTPEPTSRATRGRKNRSSGKTP---ETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSvktPETVVPTAPELQP 1287
Cdd:PHA03247 2625 DPPPPSPSPAANEPDPHPPPTVPPperPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAA---RPTVGSLTSLADP 2701
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1288 StstDQPVTPEPTSQATrgrtdrsSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPEL 1367
Cdd:PHA03247 2702 P---PPPPTPEPAPHAL-------VSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAP 2771
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1368 QPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAP 1447
Cdd:PHA03247 2772 PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP 2851
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1448 -----EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAM 1522
Cdd:PHA03247 2852 lggsvAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462492661 1523 PVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQR 1587
Cdd:PHA03247 2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPL 2996
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
850-1470 |
8.23e-15 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 81.14 E-value: 8.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 850 IRAAEKVSRGDQESPDACLPPTVPeAPAPPQKPLNSQSQKHLAPPPLlspllpsikpTVRKTRqdgsqeaPEAPlsseLE 929
Cdd:PHA03247 2537 IRGLEELASDDAGDPPPPLPPAAP-PAAPDRSVPPPRPAPRPSEPAV----------TSRARR-------PDAP----PQ 2594
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 930 PFHPKPKIRTRKSSRMTPfPATSAAPEPHPststaqpvtPKPTSQATRSRTNRSSVKTPepvVPTAPELQPSTSTDQPVT 1009
Cdd:PHA03247 2595 SARPRAPVDDRGDPRGPA-PPSPLPPDTHA---------PDPPPPSPSPAANEPDPHPP---PTVPPPERPRDDPAPGRV 2661
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1010 SEPTSQVTRGRKSRSSvKTPETVVPTALE--LQPSTSTDRPVTSEPTSQAtrgRKNRSSVKTPEPVVPTAPELQPSTSTD 1087
Cdd:PHA03247 2662 SRPRRARRLGRAAQAS-SPPQRPRRRAARptVGSLTSLADPPPPPPTPEP---APHALVSATPLPPGPAAARQASPALPA 2737
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1088 QPVT-SEPTYQATRGRKNRssvkTPEPVVPTAPElRPSTSTDRPVTPKPtsRTTRSRTNMSSVKTPETVVPTAPelqist 1166
Cdd:PHA03247 2738 APAPpAVPAGPATPGGPAR----PARPPTTAGPP-APAPPAAPAAGPPR--RLTRPAVASLSESRESLPSPWDP------ 2804
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1167 STDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSteQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEP 1246
Cdd:PHA03247 2805 ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP--PPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPP 2882
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1247 STSTDQPVTPEPTSqatrgrtnrssvktPETVVPTAPELQPSTSTDQPVTPEPTSQAtrgrtdrSSVKTPETVVPTAPEL 1326
Cdd:PHA03247 2883 VRRLARPAVSRSTE--------------SFALPPDQPERPPQPQAPPPPQPQPQPPP-------PPQPQPPPPPPPRPQP 2941
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1327 QASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSvktpESIVPIAP 1406
Cdd:PHA03247 2942 PLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWAS----SLALHEET 3017
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492661 1407 ELQPSTSRNQLVTPEPT--SRATRCRTNRSSVKTPEPVVPTAPEPH-PTTSTDQPVTPKLTSRATRR 1470
Cdd:PHA03247 3018 DPPPVSLKQTLWPPDDTedSDADSLFDSDSERSDLEALDPLPPEPHdPFAHEPDPATPEAGARESPS 3084
|
|
| FHA |
cd00060 |
forkhead associated (FHA) domain superfamily; Forkhead-associated (FHA) domains are small ... |
54-131 |
9.49e-14 |
|
forkhead associated (FHA) domain superfamily; Forkhead-associated (FHA) domains are small phosphopeptide recognition modules mostly found in eubacteria and eukaryotes. It is about 95-120 residues long that fold into an 11-stranded beta-sandwich. FHA domains can mediate the recognition of phosphorylated and non-phosphorylated substrates, as well as protein oligomerization. They specifically recognize threonine phosphorylation (pThr) accompanying activation of protein serine/threonine kinases. FHA domains show diverse ligand specificity. They may recognize the pTXXD motif, the pTXXI/L motif, and TQ clusters (singly and multiply phosphorylated). In eukaryotes, FHA superfamily members include forkhead-type transcription factors, as well as other signaling proteins, such as many regulatory proteins, kinases, phosphatases, motor proteins called kinesins, and metabolic enzymes. Many of them localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. FHA domains play important roles in human diseases, particularly in relation to DNA damage responses and cancers. In bacteria, FHA domain-containing proteins may participate in injection of viral proteins into host cells, transmembrane transporters, and cell division. FHA domain-containing proteins rarely include more than one copy of the domain. The only exception in eukaryotes is the checkpoint kinase Rad53 from Saccharomyces cerevisiae, which harbors two FHA domains (FHA1 and FHA2) flanking a central kinase domain. The two FHA domains recognize different phosphorylated targets and function independently from one another. In contrast, Mycobacterium tuberculosis ABC transporter Rv1747 contains two FHA domains but only one of them is essential for protein function.
Pssm-ID: 438714 [Multi-domain] Cd Length: 92 Bit Score: 68.46 E-value: 9.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 54 RLHIFSGAHGPEKdFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQI----LRPPKVLS 129
Cdd:cd00060 1 RLIVLDGDGGGRE-FPLTKGVVTIGRSPDCDIVLDDPSVSRRHARIEVD--GGGVYLEDLGSTNGTFVngkrITPPVPLQ 77
|
..
gi 2462492661 130 PG 131
Cdd:cd00060 78 DG 79
|
|
| FHA |
COG1716 |
Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]; |
53-131 |
2.03e-13 |
|
Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms];
Pssm-ID: 441322 [Multi-domain] Cd Length: 96 Bit Score: 67.68 E-value: 2.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 53 GRLHIFSGAHGpEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEilAWDKAPILRDCGSLNGTQI----LRPPKVL 128
Cdd:COG1716 2 ARLVVLEGPLA-GRRFPLDGGPLTIGRAPDNDIVLDDPTVSRRHARIR--RDGGGWVLEDLGSTNGTFVngqrVTEPAPL 78
|
...
gi 2462492661 129 SPG 131
Cdd:COG1716 79 RDG 81
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1192-1660 |
2.88e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 75.75 E-value: 2.88e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1192 NPESTVPIAPELPPSTSTEQP--VTPEPTSRATRGR-----------KNRSSGKTPETLVPTAPKLEPSTSTDQP-VTPE 1257
Cdd:PHA03247 2497 DPGGGGPPDPDAPPAPSRLAPaiLPDEPVGEPVHPRmltwirgleelASDDAGDPPPPLPPAAPPAAPDRSVPPPrPAPR 2576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1258 PTSQATRGRTNRSSVKtPETVVPTAPeLQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1337
Cdd:PHA03247 2577 PSEPAVTSRARRPDAP-PQSARPRAP-VDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRD 2654
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1338 SEPTSRTTRGRKNRSSVKTPEtvvPAAPELQPSTSTDQPVTPEPTSRATrgrtnrssvktpesivPIAPELQPSTSRNQL 1417
Cdd:PHA03247 2655 DPAPGRVSRPRRARRLGRAAQ---ASSPPQRPRRRAARPTVGSLTSLAD----------------PPPPPPTPEPAPHAL 2715
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1418 VTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPV-TPKLTSRATRRKTNRSSVKTPKP--VEPAASDLEPFT 1494
Cdd:PHA03247 2716 VSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPaRPPTTAGPPAPAPPAAPAAGPPRrlTRPAVASLSESR 2795
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1495 PTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSA 1574
Cdd:PHA03247 2796 ESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKP 2875
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1575 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSrkrSLATMDSPPHQ 1654
Cdd:PHA03247 2876 AAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQP---PLAPTTDPAGA 2952
|
....*.
gi 2462492661 1655 KQPQRG 1660
Cdd:PHA03247 2953 GEPSGA 2958
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
841-1386 |
7.82e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.59 E-value: 7.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 841 MPPAEKASRirAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAP 920
Cdd:PHA03247 2568 VPPPRPAPR--PSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT 2645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 921 EAPLSSELEPFHPkPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQP 1000
Cdd:PHA03247 2646 VPPPERPRDDPAP-GRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1001 STSTDQPVTSEPTSQVtrgrksrssvkTPETVVPTALELQPSTSTDRPVTSEPtsqatrgrknrssvktPEPVVPTAPEL 1080
Cdd:PHA03247 2725 PAAARQASPALPAAPA-----------PPAVPAGPATPGGPARPARPPTTAGP----------------PAPAPPAAPAA 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1081 QPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET----VV 1156
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlggsVA 2857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1157 PTAPelqisTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRA-TRGRKNRSSGKTPE 1235
Cdd:PHA03247 2858 PGGD-----VRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPqPQPQPPPPPQPQPP 2932
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1236 TLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKT 1315
Cdd:PHA03247 2933 PPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLA 3012
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492661 1316 --PETVVPTAPELQASASTDQPVTSEPTSRttrgRKNRSSVKTPETVVPAAPELQ-PSTSTDQPVTPEPTSRAT 1386
Cdd:PHA03247 3013 lhEETDPPPVSLKQTLWPPDDTEDSDADSL----FDSDSERSDLEALDPLPPEPHdPFAHEPDPATPEAGARES 3082
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
950-1290 |
1.69e-12 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 73.03 E-value: 1.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 950 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTApelQPSTSTDQPVTSEPTSQVTR---GRKSRSSV 1026
Cdd:pfam05109 471 ADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTP---TPNATSPTPAVTTPTPNATSptlGKTSPTSA 547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1027 KTPETvvPTALELQPSTSTDRPVTSEPTSQATrgrKNRSSVKTPEP--VVPTAPELQPSTST---------DQPVTSEP- 1094
Cdd:pfam05109 548 VTTPT--PNATSPTPAVTTPTPNATIPTLGKT---SPTSAVTTPTPnaTSPTVGETSPQANTtnhtlggtsSTPVVTSPp 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1095 ---TYQATRGRKNRSSVKTpepvvpTAPELRPStSTDRPVTPKPTSRTTRSRTNMSSVKTP--ETVVPTAPElqiSTSTD 1169
Cdd:pfam05109 623 knaTSAVTTGQHNITSSST------SSMSLRPS-SISETLSPSTSDNSTSHMPLLTSAHPTggENITQVTPA---STSTH 692
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1170 QPVT----PKPTSRTTRSRTNMSSVKNPESTVPIAPELPP--STSTEQPV---TPEPTSRATRGRKNRSSGKTPETLVPT 1240
Cdd:pfam05109 693 HVSTsspaPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPknATSPQAPSgqkTAVPTVTSTGGKANSTTGGKHTTGHGA 772
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492661 1241 APKLEPST----STDQPVT--------PEPTSQATRGRTNRSS--VKTPETVVPTAPELQPSTS 1290
Cdd:pfam05109 773 RTSTEPTTdyggDSTTPRTrynattylPPSTSSKLRPRWTFTSppVTTAQATVPVPPTSQPRFS 836
|
|
| BRCT_BRC1_like_rpt5 |
cd17743 |
fifth BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar ... |
1724-1790 |
1.80e-12 |
|
fifth BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins; Schizosaccharomyces pombe BRC1 is required for mitotic fidelity, specifically in the G2 phase of the cell cycle. It plays a role in chromatin organization. The family also includes Cryptococcus neoformans DNA ligase 4 (LIG4, also known as DNA ligase IV or polydeoxyribonucleotide synthase [ATP] 4), which is involved in dsDNA break repair, and plays a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining. Members in this family contain six BRCT domains. This family corresponds to the fifth one.
Pssm-ID: 349374 Cd Length: 70 Bit Score: 64.19 E-value: 1.80e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462492661 1724 KVLFTGVVDARGE--RAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1790
Cdd:cd17743 2 RLLFTGYKLWTEKeiKKLKKLGISIVEDPDECTHLVAPKIVRTEKFLCALAYAPVIVTTDWLEACLKAG 70
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1152-1513 |
1.38e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 69.95 E-value: 1.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1152 PETVVPTAPELQISTSTDQPVTPK-PTSRTTRSRTNMSSVKNPESTVpiapELPPSTSTEQPVTPEPtsratrgrknrSS 1230
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKVIFSKaPESTTTSPTLNTTGFAAPNTTT----GLPSSTHVPTNLTAPA-----------ST 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1231 GKTPETLVPTAPKLEPSTSTDQPVTPEPTSqatrgRTNRSSVKTPETVVPTAPELQPSTSTDQP----VTPEPTSQA-TR 1305
Cdd:pfam05109 465 GPTVSTADVTSPTPAGTTSGASPVTPSPSP-----RDNGTESKAPDMTSPTSAVTTPTPNATSPtpavTTPTPNATSpTL 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1306 GRTDRSSVKTPETvvPTAPELQASASTDQPVTSEPTSRTTrGRKNRSSVKTPETVVPAAPELQPSTST---------DQP 1376
Cdd:pfam05109 540 GKTSPTSAVTTPT--PNATSPTPAVTTPTPNATIPTLGKT-SPTSAVTTPTPNATSPTVGETSPQANTtnhtlggtsSTP 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1377 VTPEP----TSRATRGRTNRSSVKTPE-SIVP--IAPELQPSTSRNQ------LVTPEPTSRATRCRTNRSSVKTpEPVV 1443
Cdd:pfam05109 617 VVTSPpknaTSAVTTGQHNITSSSTSSmSLRPssISETLSPSTSDNStshmplLTSAHPTGGENITQVTPASTST-HHVS 695
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462492661 1444 PTAPEPHPTTsTDQPVTPKLTSRATrrKTNRSSVKTPKPVEPAASdlePFTPTDQ-SVTPEAIAQGGQSKT 1513
Cdd:pfam05109 696 TSSPAPRPGT-TSQASGPGNSSTST--KPGEVNVTKGTPPKNATS---PQAPSGQkTAVPTVTSTGGKANS 760
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1110-1548 |
2.11e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 69.17 E-value: 2.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1110 TPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPElqiSTSTDQPVTPKPTSRTTRSRTNMSS 1189
Cdd:pfam05109 429 TTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTPAG---TTSGASPVTPSPSPRDNGTESKAPD 505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1190 VKNPESTVPIApelPPSTSTEQPVTPEPTSRATrgrkNRSSGKTPETLVPTAPKlePSTSTDQPVTPEPTSQATRGRTNR 1269
Cdd:pfam05109 506 MTSPTSAVTTP---TPNATSPTPAVTTPTPNAT----SPTLGKTSPTSAVTTPT--PNATSPTPAVTTPTPNATIPTLGK 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1270 SSvktpetvvPTAPELQPSTSTDQPVTPEPTSQA-TRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGR 1348
Cdd:pfam05109 577 TS--------PTSAVTTPTPNATSPTVGETSPQAnTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRP 648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1349 KNRSSVKTPETVVPAAPELqPSTSTDQPVTPEPTSRATRGRTNRSSVKTPesivpiAPELQPSTsrnqlvtpepTSRATR 1428
Cdd:pfam05109 649 SSISETLSPSTSDNSTSHM-PLLTSAHPTGGENITQVTPASTSTHHVSTS------SPAPRPGT----------TSQASG 711
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1429 CRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKL---TSRATRRKTNRSSVKTPKPVEPAASDLEPFTPtdqsvtpeai 1505
Cdd:pfam05109 712 PGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTavpTVTSTGGKANSTTGGKHTTGHGARTSTEPTTD---------- 781
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 2462492661 1506 aQGGQSKTLRS--STVRAMPVPTTPEFQ-------SPVTTDQPISP-EPITQP 1548
Cdd:pfam05109 782 -YGGDSTTPRTryNATTYLPPSTSSKLRprwtftsPPVTTAQATVPvPPTSQP 833
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
933-1340 |
3.31e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 68.79 E-value: 3.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 933 PKPKIRTRKSSRMTPFPAT---SAAPEPHPSTST------AQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPS-- 1001
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKvifSKAPESTTTSPTlnttgfAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTpa 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1002 --TSTDQPVTSEPTSqvtrgRKSRSSVKTPETVVPTALELQPS--TSTDRPVTSEPTSQATRGRKNRSS----VKTPepv 1073
Cdd:pfam05109 480 gtTSGASPVTPSPSP-----RDNGTESKAPDMTSPTSAVTTPTpnATSPTPAVTTPTPNATSPTLGKTSptsaVTTP--- 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1074 VPTAPELQPSTSTDQPVTSEPTYQATrgrKNRSSVKTPEP--VVPTAPELRPSTSTDRPVTPKPTSR---TTRSRTNMSS 1148
Cdd:pfam05109 552 TPNATSPTPAVTTPTPNATIPTLGKT---SPTSAVTTPTPnaTSPTVGETSPQANTTNHTLGGTSSTpvvTSPPKNATSA 628
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1149 VKTPETVVPTAPELQIS---TSTDQPVTPKpTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEP------TS 1219
Cdd:pfam05109 629 VTTGQHNITSSSTSSMSlrpSSISETLSPS-TSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPaprpgtTS 707
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1220 RATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPV---TPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTS-TDQPV 1295
Cdd:pfam05109 708 QASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSgqkTAVPTVTSTGGKANSTTGGKHTTGHGARTSTEPTTDyGGDST 787
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 2462492661 1296 TPEPTSQATRGRTDRSSVK-TPETVVPTAPELQASASTDQPVTSEP 1340
Cdd:pfam05109 788 TPRTRYNATTYLPPSTSSKlRPRWTFTSPPVTTAQATVPVPPTSQP 833
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1180-1566 |
3.81e-11 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 67.68 E-value: 3.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1180 TTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTStdqPVTPEPT 1259
Cdd:pfam17823 53 KSSEQ*NFCAATAAPAPVTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSS---PSSAAQS 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1260 SQATRGRTNRSSVKTPETVVPTAP-ELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA--STDQPV 1336
Cdd:pfam17823 130 LPAAIAALPSEAFSAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSapATLTPA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1337 TSEPTSRTTRGRKNRSSVKTP-ETVVPAAPELQPSTSTDQPVTPepTSRATRGRTNRSSVKTPESIVPIAPELQPST--- 1412
Cdd:pfam17823 210 RGISTAATATGHPAAGTALAAvGNSSPAAGTVTAAVGTVTPAAL--ATLAAAAGTVASAAGTINMGDPHARRLSPAKhmp 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1413 SRNQLVTPEPTSRAtRCRTNRSSVKTPEPVVPTAPEPHPTtstdqpvtpkltsratrrktnrssvktpkpvePAASDLEP 1492
Cdd:pfam17823 288 SDTMARNPAAPMGA-QAQGPIIQVSTDQPVHNTAGEPTPS--------------------------------PSNTTLEP 334
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492661 1493 FTPTDQSVTPEAIAQGGQSKTLRSStvrAMPVPTTPEFQSPVTTdqpiSPEPITQPSCIKRQRAAGNPGSLAAP 1566
Cdd:pfam17823 335 NTPKSVASTNLAVVTTTKAQAKEPS---ASPVPVLHTSMIPEVE----ATSPTTQPSPLLPTQGAAGPGILLAP 401
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1303-1751 |
6.33e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 68.04 E-value: 6.33e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1303 ATRGRTDRSSVKTPETVVPTAPELQASAS-TDQPVTSEPTSRT---TRGRKNRSSVKTPETVVPAAPELQPSTsTDQPV- 1377
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPSRLAPAIlPDEPVGEPVHPRMltwIRGLEELASDDAGDPPPPLPPAAPPAA-PDRSVp 2569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1378 ----TPEPTSRATRGRTNRSSVKtPESIVPIAPELQPSTSRNQLvTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTT 1453
Cdd:PHA03247 2570 pprpAPRPSEPAVTSRARRPDAP-PQSARPRAPVDDRGDPRGPA-PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1454 STDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEP-FTPTDQSVTPEA--IAQGGQSKTLRSSTVRAMPVPTTPEF 1530
Cdd:PHA03247 2648 PPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRaARPTVGSLTSLAdpPPPPPTPEPAPHALVSATPLPPGPAA 2727
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1531 ---QSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLE-PKSQASRNQRWGAVRAAESLTAIPEPASP 1606
Cdd:PHA03247 2728 arqASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAgPPRRLTRPAVASLSESRESLPSPWDPADP 2807
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1607 QLLETPIHASQIQKVEPAGRSRFTPELQPKAS-----------------------QSRKRSLATMDSPPHQKQPQRGEVS 1663
Cdd:PHA03247 2808 PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPppppgppppslplggsvapggdvRRRPPSRSPAAKPAAPARPPVRRLA 2887
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1664 QKTViiKEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALG 1743
Cdd:PHA03247 2888 RPAV--SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLG 2965
|
....*...
gi 2462492661 1744 GSLAGSAA 1751
Cdd:PHA03247 2966 ALVPGRVA 2973
|
|
| FHA |
pfam00498 |
FHA domain; The FHA (Forkhead-associated) domain is a phosphopeptide binding motif. |
76-131 |
1.25e-10 |
|
FHA domain; The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.
Pssm-ID: 459831 [Multi-domain] Cd Length: 66 Bit Score: 58.74 E-value: 1.25e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462492661 76 VVGRMPDCSVALPFPSISKQHAEIEILAwDKAPILRDCGSLNGT-----QILRPPKVLSPG 131
Cdd:pfam00498 2 TIGRSPDCDIVLDDPSVSRRHAEIRYDG-GGRFYLEDLGSTNGTfvngqRLGPEPVRLKDG 61
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
941-1379 |
1.39e-10 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 66.14 E-value: 1.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 941 KSSRMTPFPATSAAPEPHPSTstaqpvtpKPTSQATRSRTNRSSVKTPEpvvptapelqpSTSTDQPVTSEPTSQVTRGR 1020
Cdd:pfam17823 53 KSSEQ*NFCAATAAPAPVTLT--------KGTSAAHLNSTEVTAEHTPH-----------GTDLSEPATREGAADGAASR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1021 ----KSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGrknrSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1096
Cdd:pfam17823 114 alaaAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAA----PRAAIAAASAPHAASPAPRTAASSTTAASSTT 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1097 QATRGrKNRSSVKTPEPVVPTAPELRPSTSTdrpVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKP 1176
Cdd:pfam17823 190 AASSA-PTTAASSAPATLTPARGISTAATAT---GHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVAS 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1177 TSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPeTLVPTAPKLEPSTSTDQPVTP 1256
Cdd:pfam17823 266 AAGTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQAQGPIIQVSTDQPVHNTAGEP-TPSPSNTTLEPNTPKSVASTN 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1257 EPTSQATRGRTNRSSVkTPETVVPTA--PELQPSTSTDQPvTPEPTSQATRGRTdrssvktpetvVPTAPELQASASTDQ 1334
Cdd:pfam17823 345 LAVVTTTKAQAKEPSA-SPVPVLHTSmiPEVEATSPTTQP-SPLLPTQGAAGPG-----------ILLAPEQVATEATAG 411
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 2462492661 1335 PVTSEPTSRTTRGRKnrssvktpetvVPAAPELQPSTS------TDQPVTP 1379
Cdd:pfam17823 412 TASAGPTPRSSGDPK-----------TLAMASCQLSTQgqylvvTTDPLTP 451
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1154-1542 |
4.99e-10 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 64.21 E-value: 4.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1154 TVVPTAP-ELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTV-PIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSG 1231
Cdd:pfam17823 63 ATAAPAPvTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAAdGAASRALAAAASSSPSSAAQSLPAAIAALPSEAF 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1232 KTPETLVPTAP-KLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPST--STDQPVTPEPTSQATRGRT 1308
Cdd:pfam17823 143 SAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSapATLTPARGISTAATATGHP 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1309 DRSSVKTP-ETVVPTAPELQASASTDQPVTSepTSRTTRGRKNRSSVKTPETVVPAAPELQPSTST---DQPVTPEPTSR 1384
Cdd:pfam17823 223 AAGTALAAvGNSSPAAGTVTAAVGTVTPAAL--ATLAAAAGTVASAAGTINMGDPHARRLSPAKHMpsdTMARNPAAPMG 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1385 A-TRGRTNRSSVKTPesIVPIAPELQPSTSRNQLVTPEPTSRATRCRT--NRSSVKTPEPVVPTAPEPH----PTTSTDQ 1457
Cdd:pfam17823 301 AqAQGPIIQVSTDQP--VHNTAGEPTPSPSNTTLEPNTPKSVASTNLAvvTTTKAQAKEPSASPVPVLHtsmiPEVEATS 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1458 PVTPKLTSRATRRKTNRSSVKTPKPVEPAAsdlepfTPTDQSVTPEAIAQGGqSKTLRSSTVRampvPTTpEFQSPVTTD 1537
Cdd:pfam17823 379 PTTQPSPLLPTQGAAGPGILLAPEQVATEA------TAGTASAGPTPRSSGD-PKTLAMASCQ----LST-QGQYLVVTT 446
|
....*
gi 2462492661 1538 QPISP 1542
Cdd:pfam17823 447 DPLTP 451
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
797-1304 |
1.20e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 1.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 797 PCLSPPRAIPGDQHPESPVHTEPmgiqgrgRQTVDKVMGLLNCKMPPAEKASRIRAAEKVSRGDQESPD--ACLPPTVPE 874
Cdd:PHA03247 2609 RGPAPPSPLPPDTHAPDPPPPSP-------SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLgrAAQASSPPQ 2681
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 875 APAPPQKPlnsqsqkhlapppllspllpsikPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAA 954
Cdd:PHA03247 2682 RPRRRAAR-----------------------PTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAA 2738
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 955 PEPHPS-TSTAQPVTPkptsqaTRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVV 1033
Cdd:PHA03247 2739 PAPPAVpAGPATPGGP------ARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVL 2812
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1034 PTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEP----VVPTAPelqpsTSTDQPVTSEPTYQATRGRKNRSSVK 1109
Cdd:PHA03247 2813 APAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlggsVAPGGD-----VRRRPPSRSPAAKPAAPARPPVRRLA 2887
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1110 TPEPVVPTAPELRPSTSTDRPVTPKPTSR-TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMS 1188
Cdd:PHA03247 2888 RPAVSRSTESFALPPDQPERPPQPQAPPPpQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAL 2967
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1189 SVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPEtlVPTAPKLEPSTSTDQPVTPEPTSQATRGRTN 1268
Cdd:PHA03247 2968 VPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALH--EETDPPPVSLKQTLWPPDDTEDSDADSLFDS 3045
|
490 500 510
....*....|....*....|....*....|....*..
gi 2462492661 1269 RSSVKTPETVVPTAPELQ-PSTSTDQPVTPEPTSQAT 1304
Cdd:PHA03247 3046 DSERSDLEALDPLPPEPHdPFAHEPDPATPEAGARES 3082
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
949-1502 |
1.46e-09 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 63.57 E-value: 1.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 949 PATSAAPEPHPSTSTAQPVTPKPTSQAtrsrtnrssVKTPEPVVPTAPE---LQPSTSTDQPVTSEPTSQVTRGRKSRSS 1025
Cdd:PRK10263 339 PVTQTPPVASVDVPPAQPTVAWQPVPG---------PQTGEPVIAPAPEgypQQSQYAQPAVQYNEPLQQPVQPQQPYYA 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1026 VKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGrkNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNR 1105
Cdd:PRK10263 410 PAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAG--NAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQ 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1106 SSVKtPEPVVPTAPELRPSTSTDRPVtpkpTSRTTRSRTNMSS--------VKTPETVVPTAPELqiSTSTDQPVTPKPT 1177
Cdd:PRK10263 488 PVVE-PEPVVEETKPARPPLYYFEEV----EEKRAREREQLAAwyqpipepVKEPEPIKSSLKAP--SVAAVPPVEAAAA 560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1178 SRTTRSRTNMSSVKNPESTVPIAPELPPSTSTeqpvTPEPTSRATRG----RKNRSSGKTPETLVPTAPKLePStstdQP 1253
Cdd:PRK10263 561 VSPLASGVKKATLATGAAATVAAPVFSLANSG----GPRPQVKEGIGpqlpRPKRIRVPTRRELASYGIKL-PS----QR 631
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1254 VTPEPTSQATRGRTNRSSVKTPETVVPTAPE---LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA 1330
Cdd:PRK10263 632 AAEEKAREAQRNQYDSGDQYNDDEIDAMQQDelaRQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRY 711
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1331 STDQPVTSEPTSRTTRgrkNRSSVKTPETVVPAAPELQPS-----TSTDQPVTPEPTSRATRGRTNRSSVKTPESivPIA 1405
Cdd:PRK10263 712 SGEQPAGANPFSLDDF---EFSPMKALLDDGPHEPLFTPIvepvqQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQ--PVA 786
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1406 PELQPSTSRnQLVTPEPTSRATRcRTNRSSVKTPEPVVPTAPEPhPTTSTDQPVTPKLTSRATRRKTNRSSVKTP--KPV 1483
Cdd:PRK10263 787 PQPQYQQPQ-QPVAPQPQYQQPQ-QPVAPQPQYQQPQQPVAPQP-QYQQPQQPVAPQPQDTLLHPLLMRNGDSRPlhKPT 863
|
570
....*....|....*....
gi 2462492661 1484 EPAASdLEPFTPTDQSVTP 1502
Cdd:PRK10263 864 TPLPS-LDLLTPPPSEVEP 881
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
779-1206 |
2.26e-09 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 62.78 E-value: 2.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 779 ESEDSETQpfDTHLEAYGPCLSPPRAiPGDQHPESPVHTEPMGIQG--RGRQTVDKVMGLLNCKMPPAE--KASRIRAAE 854
Cdd:PTZ00449 500 EEEDSDKH--DEPPEGPEASGLPPKA-PGDKEGEEGEHEDSKESDEpkEGGKPGETKEGEVGKKPGPAKehKPSKIPTLS 576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 855 KVSRG--DQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKT----RQDGSQEAPEAPLS--S 926
Cdd:PTZ00449 577 KKPEFpkDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRppppQRPSSPERPEGPKIikS 656
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 927 ELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPelqpstsTDQ 1006
Cdd:PTZ00449 657 PKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLP-------RDE 729
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1007 PVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTsqatrgRKNRSSVKTPEPVVPTAPELQPSTST 1086
Cdd:PTZ00449 730 EFPFEPIGDPDAEQPDDIEFFTPPEEERTFFHETPADTPLPDILAEEF------KEEDIHAETGEPDEAMKRPDSPSEHE 803
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1087 DQPVTSEPTYQATRGRKNRSSVKTPEpvVPTAPELRPSTSTDRPVTPKptsrTTRSRTNMSSVKTPETVVPTAPELQIS- 1165
Cdd:PTZ00449 804 DKPPGDHPSLPKKRHRLDGLALSTTD--LESDAGRIAKDASGKIVKLK----RSKSFDDLTTVEEAEEMGAEARKIVVDd 877
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 2462492661 1166 --TSTD----QPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPS 1206
Cdd:PTZ00449 878 dgTEADdedtHPPEEKHKSEVRRRRPPKKPSKPKKPSKPKKPKKPDS 924
|
|
| BRCT_BRC1_like_rpt6 |
cd18439 |
sixth (C-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) ... |
1806-1903 |
2.65e-09 |
|
sixth (C-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins; Schizosaccharomyces pombe BRC1 is required for mitotic fidelity, specifically in the G2 phase of the cell cycle. It plays a role in chromatin organization. The family also includes Cryptococcus neoformans DNA ligase 4 (LIG4, also known as DNA ligase IV or polydeoxyribonucleotide synthase [ATP] 4), which is involved in dsDNA break repair, and plays a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining. Members in this family contains six BRCT domains. This family corresponds to the sixth repeat.
Pssm-ID: 349392 Cd Length: 116 Bit Score: 56.54 E-value: 2.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1806 EKNFGFSLQDALSRARERR--LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKP--------QRVVITCPQD 1875
Cdd:cd18439 1 EKKYGCTLAESLARAKANKgkLLKGYTVYLTPKVKGGVETFKSIVEANGGICNLLRAAKGKLgdgiaekgPVVLISTTKE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2462492661 1876 ------------FPHCSIPLRvglpllSPEFLLTGVLKQE 1903
Cdd:cd18439 81 kklwpkflknarEGGKEPRVY------STDWLLDVVLRQE 114
|
|
| BRCT |
cd00027 |
C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains; The ... |
1723-1786 |
1.70e-08 |
|
C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains; The BRCT (BRCA1 C-terminus) domain is found within many DNA damage repair and cell cycle checkpoint proteins. BRCT domains interact with each other forming homo/hetero BRCT multimers, but are also involved in BRCT-non-BRCT interactions and interactions within DNA strand breaks. BRCT tandem repeats bind to phosphopeptides; it has been shown that the repeats in human BRCA1 bind specifically to pS-X-X-F motifs, mediating the interaction between BRCA1 and the DNA helicase BACH1, or BRCA1 and CtIP, a transcriptional corepressor. It is assumed that BRCT repeats play similar roles in many signaling pathways associated with the response to DNA damage.
Pssm-ID: 349339 [Multi-domain] Cd Length: 68 Bit Score: 52.75 E-value: 1.70e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462492661 1723 PKVLFTGVVDARGE---RAVLALGGSLAGS-AAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQS 1786
Cdd:cd00027 1 LVICFSGLDDEEREelkKLIEALGGKVSESlSSKVTHLIAKSPSGEKYYLAALAWGIPIVSPEWLLDC 68
|
|
| FHA |
smart00240 |
Forkhead associated domain; Found in eukaryotic and prokaryotic proteins. Putative nuclear ... |
76-121 |
2.96e-08 |
|
Forkhead associated domain; Found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain.
Pssm-ID: 214578 [Multi-domain] Cd Length: 52 Bit Score: 51.41 E-value: 2.96e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 2462492661 76 VVGRMP-DCSVALPFPSISKQHAEIEILAWDKApILRDCGSLNGTQI 121
Cdd:smart00240 2 TIGRSSeDCDIQLDGPSISRRHAVIVYDGGGRF-YLIDLGSTNGTFV 47
|
|
| BRCT_TopBP1_rpt7 |
cd17738 |
seventh BRCT domain of DNA topoisomerase 2-binding protein 1; TopBP1, also termed DNA ... |
1723-1790 |
1.08e-07 |
|
seventh BRCT domain of DNA topoisomerase 2-binding protein 1; TopBP1, also termed DNA topoisomerase II-beta-binding protein 1, or DNA topoisomerase II-binding protein 1, functions in DNA replication and damage response. It binds double-stranded DNA breaks and nicks as well as single-stranded DNA. TopBP1 contains six copies of BRCT domain. The family corresponds to the seventh BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is missing in this group.
Pssm-ID: 349370 [Multi-domain] Cd Length: 75 Bit Score: 50.64 E-value: 1.08e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462492661 1723 PKVLFTGVVDArgERA-----VLALGGSLAGSA---AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1790
Cdd:cd17738 2 PVFLLSGFSED--EKKelisiIEKLGGKVLDSDefdPKCTHLICGKPSRSEKFLAACAAGKWILHPSYIEASAKAG 75
|
|
| FHA_DgcB-like |
cd22682 |
forkhead associated (FHA) domain found in Bdellovibrio bacteriovorus GGDEF domain protein DgcB ... |
59-152 |
1.14e-07 |
|
forkhead associated (FHA) domain found in Bdellovibrio bacteriovorus GGDEF domain protein DgcB and similar proteins; DgcB is a GGDEF enzyme that produces cyclic-di-GMP in response to an unknown stimulus. It appends the C-terminal GGDEF enzymatic domain with an N-terminal forkhead-associated (FHA) domain that acts as a consensus phosphopeptide sensor. The GGDEF and sensory FHA domains form an asymmetrical dimer.
Pssm-ID: 438734 [Multi-domain] Cd Length: 96 Bit Score: 51.37 E-value: 1.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 59 SGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAwdKAPILRDCGSLNGTQIlrPPKVLSPGVSHRLRD 138
Cdd:cd22682 6 IGPPGVGKQFPITESTIVIGRSVESQVQIDDDSVSRYHAKLAVNP--SAVSIIDLGSTNGTIV--NGKKIPKLASCDLQN 81
|
90
....*....|....
gi 2462492661 139 QELILFADLLCQYH 152
Cdd:cd22682 82 GDQIKIGNTIFKFH 95
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1101-1509 |
1.15e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 57.10 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1101 GRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRT 1180
Cdd:PHA03307 38 GSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPP 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1181 TRSrtnMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRgrknrSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTS 1260
Cdd:PHA03307 118 PPT---PPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGA-----SPAAVASDAASSRQAALPLSSPEETARAPSSP 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1261 QATRGrTNRSSVKTPETVVPTAPELQPSTSTDQPVtPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1340
Cdd:PHA03307 190 PAEPP-PSTPPAAASPRPPRRSSPISASASSPAPA-PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPT 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1341 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRatrgRTNRSSVKTPESIVPIAPELQPSTSRNQLVTP 1420
Cdd:PHA03307 268 RIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSS----PRASSSSSSSRESSSSSTSSSSESSRGAAVSP 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1421 EPTSRATRCRTNRSSVKTPEPVvPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPvEPAASDLEPFTPTDQSV 1500
Cdd:PHA03307 344 GPSPSRSPSPSRPPPPADPSSP-RKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDAT-GRFPAGRPRPSPLDAGA 421
|
....*....
gi 2462492661 1501 TPEAIAQGG 1509
Cdd:PHA03307 422 ASGAFYARY 430
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1151-1454 |
1.24e-07 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 56.93 E-value: 1.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1151 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPeSTVPIAPELPPSTSTEQPV---TPEPTSRATRGRKN 1227
Cdd:TIGR00927 103 TPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTP-ATPSRALNHYISTSGRQRVksyTPKPRGEVKSSSPT 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1228 RSSGK----TPETLVPTAPKLEPSTSTDQPvtpeptsqATRGRTNRSSVKTPETvvpTAPELQPSTSTDQPVTPEPTSQA 1303
Cdd:TIGR00927 182 QTREKvrkyTPSPLGRMVNSYAPSTFMTMP--------RSHGITPRTTVKDSEI---TATYKMLETNPSKRTAGKTTPTP 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1304 TRGRTDRSS---VKTPETVVPTAPELQASAST-DQPVTSEPTSRTT-RGRKNRSSVKTPETVV----PAAPELQPSTSTD 1374
Cdd:TIGR00927 251 LKGMTDNTPtflTREVETDLLTSPRSVVEKNTlTTPRRVESNSSTNhWGLVGKNNLTTPQGTVlehtPATSEGQVTISIM 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1375 QPVTPEPTSRATRGRTNRS-SVKTPESIVPIAP------ELQPSTSRNQLVTPE----PTSRATRCrtnrsSVKTPEPVV 1443
Cdd:TIGR00927 331 TGSSPAETKASTAAWKIRNpLSRTSAPAVRIASatfrglEKNPSTAPSTPATPRvravLTTQVHHC-----VVVKPAPAV 405
|
330
....*....|.
gi 2462492661 1444 PTAPEPHPTTS 1454
Cdd:TIGR00927 406 PTTPSPSLTTA 416
|
|
| BRCT_microcephalin_rpt2 |
cd17736 |
second BRCT domain of microcephalin and similar proteins; Microcephalin is a DNA damage ... |
1725-1793 |
1.37e-07 |
|
second BRCT domain of microcephalin and similar proteins; Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. It has been implicated in chromosome condensation and DNA damage induced cellular responses. It may play a role in neurogenesis and regulation of the size of the cerebral cortex. Microcephalin contains three BRCT repeats. This family corresponds to the second repeat.
Pssm-ID: 349368 [Multi-domain] Cd Length: 76 Bit Score: 50.67 E-value: 1.37e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492661 1725 VLFTGVVDARGE---RAVLALGG-SLAGSAAE-ASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1793
Cdd:cd17736 3 LVMTSVHSEEQElleSVVKKLGGfRVEDSVTEkTTHVVVGSPRRTLNVLLGIARGCWILSPDWVLESLEAGKWL 76
|
|
| BRCT_nibrin |
cd17741 |
BRCT domain of nibrin and similar proteins; Nibrin (NBN), also termed Nijmegen breakage ... |
1738-1789 |
1.53e-07 |
|
BRCT domain of nibrin and similar proteins; Nibrin (NBN), also termed Nijmegen breakage syndrome protein 1 (NBS1), or cell cycle regulatory protein p95, is a novel DNA double-strand break repair protein that is mutated in Nijmegen breakage syndrome. It is a component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The BRCT (Breast Cancer Suppressor Protein BRCA1, carboxy-terminal) domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo/hetero BRCT multimers, BRCT-non-BRCT interactions, and interactions within DNA strand breaks. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is absent in this group.
Pssm-ID: 349372 [Multi-domain] Cd Length: 74 Bit Score: 50.29 E-value: 1.53e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2462492661 1738 AVLALGGSLAGSAAEAS-HLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA 1789
Cdd:cd17741 21 IIAKLGGKVVNEWTEECtHLVMSKIKVTVKVICALISGKPIVTPEYLDALLEA 73
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1048-1597 |
1.80e-07 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 56.63 E-value: 1.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1048 PVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSeptYQATRGrknrssVKTPEPVVPTAPELRPstst 1127
Cdd:PRK10263 315 PITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVA---WQPVPG------PQTGEPVIAPAPEGYP---- 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1128 drpvtPKPTSRTTRSRTNMSSVKtpetvvPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPST 1207
Cdd:PRK10263 382 -----QQSQYAQPAVQYNEPLQQ------PVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAE 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1208 STEQPVTPEPTSRATrgrknrssgKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPT-APELQ 1286
Cdd:PRK10263 451 EQQSTFAPQSTYQTE---------QTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKrARERE 521
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1287 PSTSTDQPVtPEPtsqatrgrtdrssVKTPETVVPTAPELQASASTdqPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPE 1366
Cdd:PRK10263 522 QLAAWYQPI-PEP-------------VKEPEPIKSSLKAPSVAAVP--PVEAAAAVSPLASGVKKATLATGAAATVAAPV 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1367 LQPSTSTdqpvTPEPTSRATRG----RTNRSSVKTPESIVPIAPELqPStsrnQLVTPEPTSRATRCRTNRSSVKTPEPV 1442
Cdd:PRK10263 586 FSLANSG----GPRPQVKEGIGpqlpRPKRIRVPTRRELASYGIKL-PS----QRAAEEKAREAQRNQYDSGDQYNDDEI 656
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1443 VPTAPE----------------------PHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQ-- 1498
Cdd:PRK10263 657 DAMQQDelarqfaqtqqqrygeqyqhdvPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKAll 736
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1499 -----------SVTPEAIAQgGQSKTLRSSTVRAMPVPTTPEFQSPvttDQPISPEPITQ--PSCIKRQRAAGNPGSLAA 1565
Cdd:PRK10263 737 ddgpheplftpIVEPVQQPQ-QPVAPQQQYQQPQQPVAPQPQYQQP---QQPVAPQPQYQqpQQPVAPQPQYQQPQQPVA 812
|
570 580 590
....*....|....*....|....*....|...
gi 2462492661 1566 P-IDHKPCSAPLEPKSQASRNQRWGAVRAAESL 1597
Cdd:PRK10263 813 PqPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTL 845
|
|
| RTT107_BRCT_5 |
pfam16770 |
Regulator of Ty1 transposition protein 107 BRCT domain; This is the fifth BRCT domain of ... |
1742-1798 |
6.77e-07 |
|
Regulator of Ty1 transposition protein 107 BRCT domain; This is the fifth BRCT domain of regulator of Ty1 transposition protein 107 (RTT107). It is involved in binding phosphorylated histone H2A.
Pssm-ID: 465266 Cd Length: 91 Bit Score: 49.05 E-value: 6.77e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492661 1742 LGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEY 1798
Cdd:pfam16770 33 LGIKIVQDPSKCNHLIAPKILRTEKFLCALAFAPYILSPDFITDCLKEGKLPDEEDY 89
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1204-1612 |
7.15e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 54.79 E-value: 7.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1204 PPSTSTEQPVTPeptsraTRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAP 1283
Cdd:PHA03307 24 PPATPGDAADDL------LSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1284 ELQPSTSTDQPVTPEPTSqaTRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPA 1363
Cdd:PHA03307 98 ASPAREGSPTPPGPSSPD--PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1364 APELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVV 1443
Cdd:PHA03307 176 LSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENEC 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1444 PtAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSV-----KTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSS- 1517
Cdd:PHA03307 256 P-LPRPAPITLPTRIWEASGWNGPSSRPGPASSSsspreRSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSe 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1518 TVRAMPVPTTPEFQSPVTTDQPisPEPITQPSCIKRQRAAGNPGSLAAPIDHKPC----SAPLEPKSQASRNQRWGAVRA 1593
Cdd:PHA03307 335 SSRGAAVSPGPSPSRSPSPSRP--PPPADPSSPRKRPRPSRAPSSPAASAGRPTRrrarAAVAGRARRRDATGRFPAGRP 412
|
410
....*....|....*....
gi 2462492661 1594 AESLTAIPEPASPQLLETP 1612
Cdd:PHA03307 413 RPSPLDAGAASGAFYARYP 431
|
|
| FHA_Ki67 |
cd22673 |
forkhead associated (FHA) domain found in proliferation marker protein Ki-67 and similar ... |
53-146 |
9.80e-07 |
|
forkhead associated (FHA) domain found in proliferation marker protein Ki-67 and similar proteins; Ki-67, also called antigen identified by monoclonal antibody Ki-67, antigen KI-67, or antigen Ki67, acts as a biological surfactant to disperse mitotic chromosomes. It is required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Ki-67 binds DNA with a preference for supercoiled DNA and AT-rich DNA. It may also play a role in chromatin organization. Ki-67 contains an FHA domain at its N-terminus. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438725 [Multi-domain] Cd Length: 95 Bit Score: 48.75 E-value: 9.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 53 GRLHIF--SGAHGPEkdFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKApILRDCGSLNGTQiLRPPKVLSP 130
Cdd:cd22673 1 GKLVVIkkDGTDGSR--FPLTKKSCTFGRDLSCDIRIQLPGVSREHCRIEVDENGKA-YLENLSTTNPTL-VNGKAIEKS 76
|
90
....*....|....*.
gi 2462492661 131 gvsHRLRDQELILFAD 146
Cdd:cd22673 77 ---AELKDGDVITIGG 89
|
|
| FHA_FhaA-like |
cd22668 |
forkhead associated (FHA) domain found in Mycobacterium tuberculosis FHA domain-containing ... |
62-121 |
1.59e-06 |
|
forkhead associated (FHA) domain found in Mycobacterium tuberculosis FHA domain-containing protein FhaA and similar proteins; FhaA regulates cell growth and peptidoglycan synthesis by binding to MviN. It may inhibit the late stages of peptidoglycan synthesis. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438720 [Multi-domain] Cd Length: 91 Bit Score: 47.85 E-value: 1.59e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462492661 62 HGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIeilAWD-KAPILRDCGSLNGTQI 121
Cdd:cd22668 7 DGSGRVYQLREGSNIIGRGSDADFRLPDTGVSRRHAEI---RWDgQVAHLTDLGSTNGTTV 64
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1088-1668 |
1.78e-06 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 53.17 E-value: 1.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1088 QPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTsrttrsrtnMSSVKTPETVVPTAPElqisTS 1167
Cdd:PRK10263 314 APITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQP---------VPGPQTGEPVIAPAPE----GY 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1168 TDQPVTPKPTSRttrsrtnmssvKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPS 1247
Cdd:PRK10263 381 PQQSQYAQPAVQ-----------YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1248 TSTDQPVTPEPTSQATRgrtnrssvKTPETVVPTAPELQPStSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPT-APEL 1326
Cdd:PRK10263 450 EEQQSTFAPQSTYQTEQ--------TYQQPAAQEPLYQQPQ-PVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKrARER 520
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1327 QASASTDQPVtSEPtsrttrgrknrssVKTPETVVPAAPelQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAP 1406
Cdd:PRK10263 521 EQLAAWYQPI-PEP-------------VKEPEPIKSSLK--APSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAP 584
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1407 ELQPSTSRnqlvTPEPtsratrcrtnrssvKTPEPVVPTAPEPH----PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKP 1482
Cdd:PRK10263 585 VFSLANSG----GPRP--------------QVKEGIGPQLPRPKrirvPTRRELASYGIKLPSQRAAEEKAREAQRNQYD 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1483 VEPAASDLEpftpTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEfqspvTTDQPISPEPITQPSCIKRQRAAG---- 1558
Cdd:PRK10263 647 SGDQYNDDE----IDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAE-----DADAAAEAELARQFAQTQQQRYSGeqpa 717
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1559 --NPGSLA----APID-------HKPCSAP-LEPKSQASRNQRWGAVRAAESLTAIPEPA--SPQLLETPIHASQIQKVE 1622
Cdd:PRK10263 718 gaNPFSLDdfefSPMKallddgpHEPLFTPiVEPVQQPQQPVAPQQQYQQPQQPVAPQPQyqQPQQPVAPQPQYQQPQQP 797
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 2462492661 1623 PAGRSRFTPELQPKASQSRKRSLATMDSPP---HQKQPQRGEVSQKTVI 1668
Cdd:PRK10263 798 VAPQPQYQQPQQPVAPQPQYQQPQQPVAPQpqyQQPQQPVAPQPQDTLL 846
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1001-1359 |
1.95e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 53.25 E-value: 1.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1001 STSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEP----VVPT 1076
Cdd:PHA03307 61 ACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPdlseMLRP 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1077 APELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRtnmssvktpetvv 1156
Cdd:PHA03307 141 VGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPP------------- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1157 PTAPELQISTSTDQPVTPKpTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPET 1236
Cdd:PHA03307 208 RRSSPISASASSPAPAPGR-SAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPAS 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1237 LVPTAPKLEPSTSTDQPVTPEPTSQAT--RGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVK 1314
Cdd:PHA03307 287 SSSSPRERSPSPSPSSPGSGPAPSSPRasSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPR 366
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462492661 1315 TPETVVPTAPELQASAST-----------DQPVTSEPTSRTTRGRKNRSSVKTPET 1359
Cdd:PHA03307 367 KRPRPSRAPSSPAASAGRptrrraraavaGRARRRDATGRFPAGRPRPSPLDAGAA 422
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
963-1189 |
3.45e-06 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 51.73 E-value: 3.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 963 TAQPVTPKP-------TSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRS-SVKTPETVVP 1034
Cdd:PRK13914 144 TSTPVAPTQevkkettTQQAAPAAETKTEVKQTTQATTPAPKVAETKETPVVDQNATTHAVKSGDTIWAlSVKYGVSVQD 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1035 TALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVP--TAPELQPSTSTDQPVTSeptyqatrgrknRSSVKTPE 1112
Cdd:PRK13914 224 IMSWNNLSSSSIYVGQKLAIKQTANTATPKAEVKTEAPAAEkqAAPVVKENTNTNTATTE------------KKETTTQQ 291
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492661 1113 PVVPTAPelrpsTSTDRPvTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS 1189
Cdd:PRK13914 292 QTAPKAP-----TEAAKP-APAPSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSSNNNS 362
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
869-1243 |
3.59e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 52.38 E-value: 3.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 869 PPTVPEAPA-PPQKPLNSQSQ-KHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAP-------EAPLSSEL-----EPFHPK 934
Cdd:PTZ00449 510 PPEGPEASGlPPKAPGDKEGEeGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPakehkpsKIPTLSKKpefpkDPKHPK 589
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 935 PKIRTRKSSRmtpfPATSAAPEPHPSTSTAQPVT-PKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTS-EP 1012
Cdd:PTZ00449 590 DPEEPKKPKR----PRSAQRPTRPKSPKLPELLDiPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSpKP 665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1013 TSQVTRGRK-----SRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGR-------KNRSSVKTPePVVPTAPEL 1080
Cdd:PTZ00449 666 PFDPKFKEKfyddyLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRplppklpRDEEFPFEP-IGDPDAEQP 744
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1081 QPSTSTDQPVTSEPTYQATRGRKNRSSV-----KTP----EPVVPTAPELRPSTST---DRPVTPKPTSRTTRSRTNMSS 1148
Cdd:PTZ00449 745 DDIEFFTPPEEERTFFHETPADTPLPDIlaeefKEEdihaETGEPDEAMKRPDSPSeheDKPPGDHPSLPKKRHRLDGLA 824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1149 VKTPEtvVPTAPELQISTSTDQPVTPKptsrttRSRTNmssvkNPESTVPIAPELPPSTS--------TE------QPVT 1214
Cdd:PTZ00449 825 LSTTD--LESDAGRIAKDASGKIVKLK------RSKSF-----DDLTTVEEAEEMGAEARkivvdddgTEaddedtHPPE 891
|
410 420
....*....|....*....|....*....
gi 2462492661 1215 PEPTSRATRGRKNRSSGKTPETLVPTAPK 1243
Cdd:PTZ00449 892 EKHKSEVRRRRPPKKPSKPKKPSKPKKPK 920
|
|
| FHA_PP2C70-like |
cd22678 |
forkhead associated (FHA) domain found in Arabidopsis thaliana protein phosphatase 2C 70 ... |
77-143 |
3.90e-06 |
|
forkhead associated (FHA) domain found in Arabidopsis thaliana protein phosphatase 2C 70 (AtPP2C70) and similar proteins; AtPP2C70, also called kinase-associated protein phosphatase, or protein ROOT ATTENUATED GROWTH 1, dephosphorylates the serine/threonine receptor-like kinase RLK5. It may function as a signaling component in a pathway involving RLK5. It acts as a negative regulator of the CLAVATA1 signaling in plant development by binding and dephosphorylating CLAVATA1. It is also a component of a signaling pathway which mediates adaptation to NaCl stress. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438730 [Multi-domain] Cd Length: 102 Bit Score: 47.36 E-value: 3.90e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462492661 77 VGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQI-LRPPKVlsPGVSHRLRDQELIL 143
Cdd:cd22678 27 IGRIQRGDIALKDDEVSGKHARIEWNSTGSKWELVDLGSLNGTLVnGESISP--NGRPVVLSSGDVIT 92
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
1072-1506 |
5.39e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 51.61 E-value: 5.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1072 PVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAP----ELRPS---TSTDRPVTPKPTsrttrsrt 1144
Cdd:PTZ00449 514 PEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPgpakEHKPSkipTLSKKPEFPKDP-------- 585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1145 nmssvKTPETvvPTAPElqistSTDQPVTP-KPTSRttrsrtnmSSVKNPEST-VPIAPELPPSTSTeqPVTPEPTSRAT 1222
Cdd:PTZ00449 586 -----KHPKD--PEEPK-----KPKRPRSAqRPTRP--------KSPKLPELLdIPKSPKRPESPKS--PKRPPPPQRPS 643
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1223 RGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSq 1302
Cdd:PTZ00449 644 SPERPEGPKIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLP- 722
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1303 ATRGRTDRSSVKTPETvvPTAPElqasaSTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPept 1382
Cdd:PTZ00449 723 PKLPRDEEFPFEPIGD--PDAEQ-----PDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEEDIHAETGEPDEA--- 792
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1383 srATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATR---------CRTNRSSVKTPEPVVPTAPEPHP-- 1451
Cdd:PTZ00449 793 --MKRPDSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDLESDAGRiakdasgkiVKLKRSKSFDDLTTVEEAEEMGAea 870
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492661 1452 ---------TTSTDQPVTP---KLTSRATRRKTNRSSVKTPKPVEPAasdlEPFTPtDQSVTPEAIA 1506
Cdd:PTZ00449 871 rkivvdddgTEADDEDTHPpeeKHKSEVRRRRPPKKPSKPKKPSKPK----KPKKP-DSAFIPSIIA 932
|
|
| FHA_Kanadaptin |
cd22677 |
forkhead associated (FHA) domain found in kanadaptin and similar proteins; Kanadaptin, also ... |
76-137 |
5.56e-06 |
|
forkhead associated (FHA) domain found in kanadaptin and similar proteins; Kanadaptin, also called human lung cancer oncogene 3 protein (HLC-3), kidney anion exchanger adapter protein, or solute carrier family 4 anion exchanger member 1 adapter protein (SLC4A1AP), is a nuclear protein widely expressed in mammalian tissues. It was originally isolated as a kidney Cl-/HCO3- anion exchanger 1 (kAE1)-binding protein. It is a highly mobile nucleocytoplasmic shuttling and multilocalizing protein. Its role in mammalian cells remains unclear. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438729 [Multi-domain] Cd Length: 106 Bit Score: 46.78 E-value: 5.56e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462492661 76 VVGRMPDCSVALPFPSISKQHAeieILAWDKAPI-------LRDCGSLNGTQILRPPkvLSPGVSHRLR 137
Cdd:cd22677 25 VFGRLPGCDVVLEHPSISRYHA---VLQYRGDADdhdggfyLYDLGSTHGTFLNKQR--IPPKQYYRLR 88
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
1245-1372 |
6.72e-06 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 51.25 E-value: 6.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1245 EPSTSTDQPVTPEPTSQATrgrtnrssvkTPETVVPTAPELQPSTsTDQPVTPEPTSQATRGrTDRSSVKTPETVVPTAP 1324
Cdd:NF033875 49 QPGTTTVQPDNPDPQSGSE----------TPKTAVSEEATVQKDT-TSQPTKVEEVASEKNG-AEQSSATPNDTTNAQQP 116
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2462492661 1325 ELQASAST-DQPVTSEPTSRTTRGRknrssvktPETVVPAAPELQPSTS 1372
Cdd:NF033875 117 TVGAEKSAqEQPVVSPETTNEPLGQ--------PTEVAPAENEANKSTS 157
|
|
| BRCT_p53bp1_rpt1 |
cd17745 |
first (central) BRCT domain in p53-binding protein 1 (p53BP1) and similar proteins; p53BP1, ... |
1756-1790 |
7.93e-06 |
|
first (central) BRCT domain in p53-binding protein 1 (p53BP1) and similar proteins; p53BP1, also termed 53BP1, or TP53-binding protein 1 (TP53BP1) , is a double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. TP53BP1 contains two tandem BRCT repeats. This family also includes Schizosaccharomyces pombe Crb2, which is a checkpoint mediator required for the cellular response to DNA damage. This model corresponds to the first BRCT domain.
Pssm-ID: 349376 [Multi-domain] Cd Length: 99 Bit Score: 46.15 E-value: 7.93e-06
10 20 30
....*....|....*....|....*....|....*
gi 2462492661 1756 LVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1790
Cdd:cd17745 64 LIADSPSRTPKYLQALALGIPCVSHKWILDCIEAG 98
|
|
| FHA_PS1-like |
cd22691 |
forkhead associated (FHA) domain found in Arabidopsis thaliana Protein PARALLEL SPINDLE 1 (PS1) ... |
76-119 |
1.00e-05 |
|
forkhead associated (FHA) domain found in Arabidopsis thaliana Protein PARALLEL SPINDLE 1 (PS1) and similar proteins; PS1 is an FHA domain-containing protein required for normal spindle orientation at male meiosis II and normal formation of tetrad of microspores. It is not involved in female meiosis. Mutations in PS1 lead to the production of diploid pollen grains. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438743 [Multi-domain] Cd Length: 113 Bit Score: 46.26 E-value: 1.00e-05
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 2462492661 76 VVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGT 119
Cdd:cd22691 32 VVGRHPDCDIVLDHPSISRFHLEIRIIPSRRKITLTDLSSVHGT 75
|
|
| FHA_ArnA-like |
cd22680 |
forkhead associated (FHA) domain found in Sulfolobus Acidocaldarius FHA domain-containing ... |
55-131 |
1.29e-05 |
|
forkhead associated (FHA) domain found in Sulfolobus Acidocaldarius FHA domain-containing protein ArnA and similar proteins; ArnA is an FHA domain-containing protein from Sulfolobus acidocaldarius that was shown to strongly interact with ArnB, a von Willebrand domain-containing protein. They act synergistically and negatively to modulate motility. ArnA is involved in regulating archaella expression in S. acidocaldarius. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438732 [Multi-domain] Cd Length: 96 Bit Score: 45.41 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 55 LHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQI-----LRPPKVLS 129
Cdd:cd22680 3 LEILSSPNLTGKKFPFDFSSVSIGRDPENVIVIPDPFVSRNHARITVD--SNEIYIEDLGSTNGTFVndfkrIKGPAKLH 80
|
..
gi 2462492661 130 PG 131
Cdd:cd22680 81 PN 82
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
851-1234 |
1.51e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 851 RAAEKVSRGDQESPDACLPPTVPEAPAP-PQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELE 929
Cdd:PHA03307 46 DSAELAAVTVVAGAAACDRFEPPTGPPPgPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPAS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 930 PFHPkpkirtrkssrmTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTdqPVT 1009
Cdd:PHA03307 126 PPPS------------PAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSS--PPA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1010 SEPTSQVTRGRKSRSSVKTPetvvptalELQPSTSTDRPVtSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQP 1089
Cdd:PHA03307 192 EPPPSTPPAAASPRPPRRSS--------PISASASSPAPA-PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1090 VTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRttrsRTNMSSVKTPETVVPTAPELQISTSTD 1169
Cdd:PHA03307 263 ITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSS----PRASSSSSSSRESSSSSTSSSSESSRG 338
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492661 1170 QPVTPKPTSRT--TRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTP 1234
Cdd:PHA03307 339 AAVSPGPSPSRspSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATG 405
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1019-1387 |
1.60e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 1.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1019 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTyqA 1098
Cdd:PHA03307 38 GSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSP--D 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1099 TRGRKNRSSVKTPEPVVPTAPELR---PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPElqistSTDQPVTPK 1175
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSEMLRpvgSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEE-----TARAPSSPP 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1176 PTSRTTRSRTNMSSVKNPEStVPIAPELPPSTSTeqpvtPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVT 1255
Cdd:PHA03307 191 AEPPPSTPPAAASPRPPRRS-SPISASASSPAPA-----PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPIT 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1256 PEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQAtrgRTDRSSVKTPETVvpTAPELQASASTDQP 1335
Cdd:PHA03307 265 LPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP---RASSSSSSSRESS--SSSTSSSSESSRGA 339
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 2462492661 1336 VTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATR 1387
Cdd:PHA03307 340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
916-1262 |
1.67e-05 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 49.99 E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 916 SQEAPEAPLSSELEPFHPKPkirTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPePVVPTA 995
Cdd:TIGR00927 76 SSDPPKSSSEMEGEMLAPQA---TVGRDEATPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTP-ATPSRA 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 996 PELQPSTSTDQPVTSepTSQVTRG-RKSRSSVKTPETVvptalelqpststdRPVTSEPtsqatRGRKNRSSVKTPEPVV 1074
Cdd:TIGR00927 152 LNHYISTSGRQRVKS--YTPKPRGeVKSSSPTQTREKV--------------RKYTPSP-----LGRMVNSYAPSTFMTM 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1075 PTAPELQP-STSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTD---------RPVTPKPTSRTTRSRT 1144
Cdd:TIGR00927 211 PRSHGITPrTTVKDSEITATYKMLETNPSKRTAGKTTPTPLKGMTDNTPTFLTREvetdlltspRSVVEKNTLTTPRRVE 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1145 NMSS-----------VKTPETVV----PTAPELQISTSTDQPVTPKptsrTTRSRTNMSSVKNPES-----TVPIAP--- 1201
Cdd:TIGR00927 291 SNSStnhwglvgknnLTTPQGTVlehtPATSEGQVTISIMTGSSPA----ETKASTAAWKIRNPLSrtsapAVRIASatf 366
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462492661 1202 ---ELPPSTSTEQPVTPEPTSRATRgRKNRSSGKTPETLVPTAPklEPS-TSTDQPVTPEPTSQA 1262
Cdd:TIGR00927 367 rglEKNPSTAPSTPATPRVRAVLTT-QVHHCVVVKPAPAVPTTP--SPSlTTALFPEAPSPSPSA 428
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
790-1142 |
2.44e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.78 E-value: 2.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 790 THLEAYGPClspPRAIPGDQHPESPVHTEPMGiqgrgrqtvdKVMGLLNCKMPPAEKASrIRAAEKVSRGDQESPDACLP 869
Cdd:PHA03307 54 TVVAGAAAC---DRFEPPTGPPPGPGTEAPAN----------ESRSTPTWSLSTLAPAS-PAREGSPTPPGPSSPDPPPP 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 870 PTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEA--PLSSELEPFHPKPKIRTRKSSRMTP 947
Cdd:PHA03307 120 TPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAalPLSSPEETARAPSSPPAEPPPSTPP 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 948 FPATSAAPEPHPSTSTAQP---VTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRS 1024
Cdd:PHA03307 200 AAASPRPPRRSSPISASASspaPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPS 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1025 SVKTPETVVPTALELQPSTSTDRPVTSEPTSQATrgrkNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKN 1104
Cdd:PHA03307 280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPR----ASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSR 355
|
330 340 350
....*....|....*....|....*....|....*...
gi 2462492661 1105 RSSVKTPEPvVPTAPELRPSTSTDRPVTPKPTSRTTRS 1142
Cdd:PHA03307 356 PPPPADPSS-PRKRPRPSRAPSSPAASAGRPTRRRARA 392
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
942-1249 |
2.61e-05 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 49.23 E-value: 2.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 942 SSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPStSTDQPVTSEPTSQVTRGRK 1021
Cdd:PHA03369 349 KTASLTAPSRVLAAAAKVAVIAAPQTHTGPADRQRPQRPDGIPYSVPARSPMTAYPPVPQ-FCGDPGLVSPYNPQSPGTS 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1022 SRSSVKTPETVVPTALELQPSTSTDRPVTSEPT-SQATRGRKNRSSVKtpEPVVPTAPELQPSTSTDQPVTSEPTYQATR 1100
Cdd:PHA03369 428 YGPEPVGPVPPQPTNPYVMPISMANMVYPGHPQeHGHERKRKRGGELK--EELIETLKLVKKLKEEQESLAKELEATAHK 505
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1101 GRKNRSS--------VKTPEPVV---PTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVP----TAPELQIS 1165
Cdd:PHA03369 506 SEIKKIAesefknagAKTAAANIepnCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSftstTLAAAAGQ 585
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1166 TSTDQPVTPKPTSRTTrsrTNMSSVKNPESTVpiAPELPPSTSTEQPvTPEPTSRATRGRKNRSSGKTpETLVPTAPKLE 1245
Cdd:PHA03369 586 GSDTAEALAGAIETLL---TQASAQPAGLSLP--APAVPVNASTPAS-TPPPLAPQEPPQPGTSAPSL-ETSLPQQKPVL 658
|
....
gi 2462492661 1246 PSTS 1249
Cdd:PHA03369 659 SKGA 662
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
949-1394 |
2.84e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.21 E-value: 2.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 949 PATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSsvkt 1028
Cdd:PRK07764 390 GAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ---- 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1029 petvvPTALELQPSTSTDRPVTSEPTSQATrgrknrssvkTPEPVVPTAPELQPSTSTDQPVTSE-PTYQATRGRKNRSS 1107
Cdd:PRK07764 466 -----PAPAPAAAPEPTAAPAPAPPAAPAP----------AAAPAAPAAPAAPAGADDAATLRERwPEILAAVPKRSRKT 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1108 --VKTPEPVVPtapELRPSTSTdrpvtpkPTSRTTRSRTNMSSVKTPETVVpTApelqISTSTDQPVTPKPTSRTTRSRT 1185
Cdd:PRK07764 531 waILLPEATVL---GVRGDTLV-------LGFSTGGLARRFASPGNAEVLV-TA----LAEELGGDWQVEAVVGPAPGAA 595
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1186 NMSSVKNPESTVPI--APELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQAT 1263
Cdd:PRK07764 596 GGEGPPAPASSGPPeeAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG 675
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1264 RGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPePTSQATRGRTDRSSVKTpetvvpTAPELQASASTDQPVTSEPTSR 1343
Cdd:PRK07764 676 AAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATP-PAGQADDPAAQPPQAAQ------GASAPSPAADDPVPLPPEPDDP 748
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 2462492661 1344 TTRGRKNRSSVKTPETVVPAAP--ELQPSTSTDQPVTPEPTSRATRGRTNRSS 1394
Cdd:PRK07764 749 PDPAGAPAQPPPPPAPAPAAAPaaAPPPSPPSEEEEMAEDDAPSMDDEDRRDA 801
|
|
| FHA_MEK1-like |
cd22670 |
forkhead associated (FHA) domain found in Saccharomyces cerevisiae meiosis-specific serine ... |
52-131 |
3.37e-05 |
|
forkhead associated (FHA) domain found in Saccharomyces cerevisiae meiosis-specific serine/threonine-protein kinase MEK1 and similar proteins; MEK1 (EC 2.7.11.1), also known as MRE4, is a meiosis-specific protein kinase required for chromosome synapsis and meiotic recombination. The recruitment and activation of MEK1 require the phosphorylation of the chromosome axis protein Hop1 at Thr318 (pT318), which is necessary for recognition by the MEK1 FHA domain. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438722 [Multi-domain] Cd Length: 105 Bit Score: 44.53 E-value: 3.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 52 VGRLHIFSGAhGPEKDFPLHLGKNV-VGRMPDCSVALPFPSISKQHAEIEILAWDK--API--LRDCgSLNGTQI----- 121
Cdd:cd22670 1 VGKLEVSSPG-STDIVLPIYKNQVItIGRSPSCDIVINDPFVSRTHCRIYSVQFDEssAPLvyVEDL-SSNGTYLngkli 78
|
90
....*....|.
gi 2462492661 122 -LRPPKVLSPG 131
Cdd:cd22670 79 gRNNTVLLSDG 89
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
1200-1491 |
1.53e-04 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 46.60 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1200 APELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAP-KLEPSTSTDQPVTPEPTSQAT--RGRTNRSSVKTPE 1276
Cdd:pfam04747 189 APAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPaSVEQVVEQPKVVTEEPHQQAApqEKKNKKNKRKSES 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1277 TVVPTAPE--LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTsrTTRGRKNRSSV 1354
Cdd:pfam04747 269 ENVPAASEtpVEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLDFV--TAKEEPKDEPA 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1355 KTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKT------PESIVPIAPELQPSTSRNQLVTPEPTSRATR 1428
Cdd:pfam04747 347 ETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESekvteqPVESAPAPPQVEQVVETTPPASENKKKNKKD 426
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462492661 1429 CRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLE 1491
Cdd:pfam04747 427 KKKSESEKAVEEPVQAAPSSKKPTADDNMDFLDFVTAKPDKSESVEEHIAAPMIVEPAHADEE 489
|
|
| FHA_AGGF1 |
cd22686 |
forkhead associated (FHA) domain found in angiogenic factor with G patch and FHA domains 1 ... |
46-153 |
2.92e-04 |
|
forkhead associated (FHA) domain found in angiogenic factor with G patch and FHA domains 1 (AGGF1) and similar proteins; AGGF1, also called angiogenic factor VG5Q, or G patch domain-containing protein 7 (GPATC7), or vasculogenesis gene on 5q protein, is an angiogenic factor involved in vascular development, angiogenesis, specification of hemangioblasts, and differentiation of veins. It promotes angiogenesis and the proliferation of endothelial cells. It inhibits inflammatory effect and preserve vascular integrity in non-nervous system diseases. Mutated AGGF1 causes susceptibility to Klippel-Trenaunay syndrome, a vascular disorder. Increased AGGF1 expression is associated with tumor angiogenesis. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438738 [Multi-domain] Cd Length: 123 Bit Score: 42.27 E-value: 2.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 46 RCNVEPVGRLHIFS--GAhgpekdfplhlgknVVGRMPDCSVALPFP--SISKQHAEIEILAWDKAPILRDCGS-----L 116
Cdd:cd22686 11 ESPSLQVGSLFIVTatGA--------------TIGREKDHGHTIRIPelGVSKFHAEIYYDDDEQSYTIVDLGSqngtyL 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 2462492661 117 NGTQILRPPKVLSP-GVSHrlRDQELILFADLLCQYHR 153
Cdd:cd22686 77 NGVRISQPKEKSDPyPLTH--GDELKIGETTLLFHIHP 112
|
|
| DUF4775 |
pfam16001 |
Domain of unknown function (DUF4775); This family of proteins is functionally uncharacterized. ... |
1019-1397 |
3.00e-04 |
|
Domain of unknown function (DUF4775); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 308 and 484 amino acids in length.
Pssm-ID: 406411 [Multi-domain] Cd Length: 456 Bit Score: 45.50 E-value: 3.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1019 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRS-SVKTPEPVVPTAPELQPSTSTDQPV-----TS 1092
Cdd:pfam16001 30 GRRTRSSTRGTPTRSAETVTPPPSKKARTSPATATKSSGGKGRGARKlDVGAEEPVEQETKKKKKVQNEPEAKeekekVS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1093 EPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET-VVPTAPE-LQISTSTDQ 1170
Cdd:pfam16001 110 EPVKGKPAAKKEKKEEKKQKKKEADEKEVVEEKEKEDKEEEKTETKETDAKTAESKDQPDGVgQLPAVAEeKQNHVDEDK 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1171 PVTPKPTSR------TTRSRTNMSSVKNPEST-VPIAPELPPST------STEQPVTPEPTSRATRGRKNRSSGKTPETL 1237
Cdd:pfam16001 190 PETEEPEEKektpeeVAKAEEPPKTSENGAATdTPAAVPESESAmevdeeEKLQENTPQATADAPSDDKAVPDIKVEEKV 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1238 VPTAPKLEPSTSTDQPV---TPEPTSQATrgrTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVK 1314
Cdd:pfam16001 270 AAVSESSEEPKETSEPAkepTPEPMEVDS---SSKGSSDTAQVDTPVKEVVPAAPATESAVAAESTEASNSNNEVVEVAT 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1315 TPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPeLQPSTSTDQPVTPEPTSRATRGRTNRSS 1394
Cdd:pfam16001 347 EVKEDVPEVPPKEAESSEEPAKEAESTTAENSTPVADEVATAPASNDVSKP-VAPVAVIDTTLVETPESPVKEPQVICEV 425
|
...
gi 2462492661 1395 VKT 1397
Cdd:pfam16001 426 NKS 428
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
942-1133 |
3.76e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 3.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 942 SSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRtnrssvktpEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRK 1021
Cdd:PRK07764 600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA---------EASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1022 SRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTD--QPVTSEPTYQAT 1099
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADdpVPLPPEPDDPPD 750
|
170 180 190
....*....|....*....|....*....|....*.
gi 2462492661 1100 RGRKNRSSVKTPEPVVPTAP--ELRPSTSTDRPVTP 1133
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPaaAPPPSPPSEEEEMA 786
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
970-1138 |
4.32e-04 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 45.04 E-value: 4.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 970 KPTSQATRSRTNRSSVKTPEPVVPT--APELQPSTSTDQPVTSEPTSQVT---RGRKSRSSVKTPETVVPTALELQPSTS 1044
Cdd:pfam05539 167 EPKTAVTTSKTTSWPTEVSHPTYPSqvTPQSQPATQGHQTATANQRLSSTepvGTQGTTTSSNPEPQTEPPPSQRGPSGS 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1045 TDRPVTSEPTSQATRGRKNRSsvkTPEPVVPTAPElqPSTSTDQPVTSEPTYQATRGRKnrssvKTPEPVVPTAPELRPS 1124
Cdd:pfam05539 247 PQHPPSTTSQDQSTTGDGQEH---TQRRKTPPATS--NRRSPHSTATPPPTTKRQETGR-----PTPRPTATTQSGSSPP 316
|
170
....*....|....
gi 2462492661 1125 TSTDRPVTPKPTSR 1138
Cdd:pfam05539 317 HSSPPGVQANPTTQ 330
|
|
| Yop-YscD_cpl |
pfam16697 |
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain ... |
57-140 |
5.16e-04 |
|
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus.
Pssm-ID: 465238 [Multi-domain] Cd Length: 94 Bit Score: 41.09 E-value: 5.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 57 IFSGAH-GpeKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILA--WdkapILRDCGSLNGT-----------QIL 122
Cdd:pfam16697 2 VLSGPHaG--AEFPLEGGRYRIGSDPDCDIVLSDKEVSRVHLKLEVDDegW----RLDDLGSGNGTlvngqrvtelgIAL 75
|
90
....*....|....*....
gi 2462492661 123 RPPKVLSPGVSH-RLRDQE 140
Cdd:pfam16697 76 RPGDRIELGQTEfCLVPAD 94
|
|
| FHA_EspA-like |
cd22698 |
forkhead associated (FHA) domain found in Myxococcus xanthus EspA and similar proteins; EspA ... |
63-121 |
5.34e-04 |
|
forkhead associated (FHA) domain found in Myxococcus xanthus EspA and similar proteins; EspA is a histidine protein kinase with a fork head-associated (FHA) domain at the N-terminus and a receiver domain at the C-terminus. It functions as an inhibitor of sporulation during early fruiting body development while cells are aggregating into raised mounds. EspA is part of a two-component signal transduction system that regulates the timing of sporulation initiation. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438750 [Multi-domain] Cd Length: 93 Bit Score: 40.86 E-value: 5.34e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462492661 63 GPEKDFPLHL--GKNVVGRMPDCSVALPFPSISKQHAEIEiLAWDKApILRDCGSLNGTQI 121
Cdd:cd22698 9 GSEEGKDYELdqDEFTIGRSSNNDIRLNDHSVSRHHARIV-RQGDKC-NLTDLGSTNGTFL 67
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1163-1302 |
6.71e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 44.32 E-value: 6.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1163 QISTSTDQPVTPKPTSrttrSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAP 1242
Cdd:PRK12799 292 QIDTHGTVPVAAVTPS----SAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALP 367
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1243 KLEPSTSTDQPVTPEPTSQATRGRTNRSSvKTPETVVPTAPelqpststDQPVTPEPTSQ 1302
Cdd:PRK12799 368 AAEPVNMQPQPMSTTETQQSSTGNITSTA-NGPTTSLPAAP--------ASNIPVSPTSR 418
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
843-1180 |
8.32e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 44.37 E-value: 8.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 843 PAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTrQDGSQEAPEA 922
Cdd:pfam03154 191 TTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPS-QVSPQPLPQP 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 923 PLSSELEPF------------HPKP----KIRTRKSSRMTPFPATSAAPEPHPSTSTaqpvTPKPTSQATRSRTNRSSVK 986
Cdd:pfam03154 270 SLHGQMPPMphslqtgpshmqHPVPpqpfPLTPQSSQSQVPPGPSPAAPGQSQQRIH----TPPSQSQLQSQQPPREQPL 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 987 TPEPVvpTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQP--STSTDRPVTSEP-------TSQA 1057
Cdd:pfam03154 346 PPAPL--SMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPlsSLSTHHPPSAHPpplqlmpQSQQ 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1058 TRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYqatrgrknrssvkTPEPVVPTAPELRPSTSTDRPVTPK--P 1135
Cdd:pfam03154 424 LPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPF-------------PQHPFVPGGPPPITPPSGPPTSTSSamP 490
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 2462492661 1136 TSRTTRSRTNMSSVKTPETVVPTAPELQIST----STDQPVTPKPTSRT 1180
Cdd:pfam03154 491 GIQPPSSASVSSSGPVPAAVSCPLPPVQIKEealdEAEEPESPPPPPRS 539
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1273-1494 |
9.99e-04 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 44.15 E-value: 9.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1273 KTPETVVPTAPELQPSTSTDQPVTPEPTSQATRG---RTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTrgrk 1349
Cdd:PLN03209 337 DGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPlspYTAYEDLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDV---- 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1350 nrSSVKTPETVVPAAPELQPSTSTDQPVTP--------EPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPE 1421
Cdd:PLN03209 413 --VPSPGSASNVPEVEPAQVEAKKTRPLSPyaryedlkPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPP 490
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492661 1422 PT-SRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPvepaaSDLEPFT 1494
Cdd:PLN03209 491 PAnMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQPKP-----RPLSPYT 559
|
|
| PHA03255 |
PHA03255 |
BDLF3; Provisional |
1300-1459 |
1.12e-03 |
|
BDLF3; Provisional
Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 42.58 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1300 TSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPelqpstSTDQPVTP 1379
Cdd:PHA03255 27 SGSSTASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVP------TTSNASTI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1380 EPTSRATRGRTNRSSVKTPESivpiapelQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPV-----------VPTAP- 1447
Cdd:PHA03255 101 NVTTKVTAQNITATEAGTGTS--------TGVTSNVTTRSSSTTSATTRITNATTLAPTLSSKgtsnatkttaeLPTVPd 172
|
170
....*....|..
gi 2462492661 1448 EPHPTTSTDQPV 1459
Cdd:PHA03255 173 ERQPSLSYGLPL 184
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
906-1312 |
1.15e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.82 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 906 PTVRKTRQDGSQEAPEAPlsselEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV 985
Cdd:PRK07764 418 AAAAAPAPAAAPQPAPAP-----APAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 986 KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVV----PTALELQPSTSTDR-----PVTSEPTSQ 1056
Cdd:PRK07764 493 APAAPAAPAAPAGADDAATLRERWPEILAAVPKRSRKTWAILLPEATVlgvrGDTLVLGFSTGGLArrfasPGNAEVLVT 572
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1057 ATRGRKNRssVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRgrknrssvktpepvvPTAPElrpstSTDRPVTPKPT 1136
Cdd:PRK07764 573 ALAEELGG--DWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAAR---------------PAAPA-----APAAPAAPAPA 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1137 SRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSrtnmssvknPESTVPIAPELPPSTSTEQPVTPE 1216
Cdd:PRK07764 631 GAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAA---------PAAPPPAPAPAAPAAPAGAAPAQP 701
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1217 PTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTD--QPVTPEPTSQATRGRTNRSSVKTPETVVPTAP--ELQPSTSTD 1292
Cdd:PRK07764 702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADdpVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPaaAPPPSPPSE 781
|
410 420
....*....|....*....|
gi 2462492661 1293 QPVTPEPTSQATRGRTDRSS 1312
Cdd:PRK07764 782 EEEMAEDDAPSMDDEDRRDA 801
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
1082-1282 |
1.17e-03 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 43.64 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1082 PSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPelRPSTSTDRPVTPK-PTSRTTRSR----------------- 1143
Cdd:PRK13914 147 PVAPTQEVKKETTTQQAAPAAETKTEVKQTTQATTPAP--KVAETKETPVVDQnATTHAVKSGdtiwalsvkygvsvqdi 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1144 ---TNMSS--------VKTPETVVPTAPELQisTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE-- 1210
Cdd:PRK13914 225 mswNNLSSssiyvgqkLAIKQTANTATPKAE--VKTEAPAAEKQAAPVVKENTNTNTATTEKKETTTQQQTAPKAPTEaa 302
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462492661 1211 QPvTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTA 1282
Cdd:PRK13914 303 KP-APAPSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSSNNNSNSSASAIIAEA 373
|
|
| FHA_Cep170 |
cd22704 |
forkhead associated (FHA) domain found in the centrosomal protein of 170 kDa protein (Cep170) ... |
77-119 |
1.20e-03 |
|
forkhead associated (FHA) domain found in the centrosomal protein of 170 kDa protein (Cep170) family; The Cep170 family includes Cep170 and Cep170B. Cep170, also called Cep170A, KARP-1-binding protein, or KARP1-binding protein, is a protein that localizes to centrosomes as well as spindle microtubules and plays a role in microtubule organization and microtubule assembly. It is required for centriole subdistal appendage assembly. Cep170 is phosphorylated during M phase and interacts with Polo-like kinase 1 (Plk1). Cep170B, also called centrosomal protein 170B, plays a role in microtubule organization. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438756 [Multi-domain] Cd Length: 102 Bit Score: 40.00 E-value: 1.20e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2462492661 77 VGRmPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGT 119
Cdd:cd22704 21 VGR-EDCDLILQSRSVDKQHAVITYDQIDNEFKIKDLGSLNGT 62
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
866-1377 |
1.30e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.92 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 866 ACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELE-PFHPKPKIRTRKSSR 944
Cdd:PRK10263 335 APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQqPVQPQQPYYAPAAEQ 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 945 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTP-----------EPVVPTAPELQPStSTDQPVTSEPT 1013
Cdd:PRK10263 415 PAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPqstyqteqtyqQPAAQEPLYQQPQ-PVEQQPVVEPE 493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1014 SQVTRGRKSRSSVKTPETVVPT-ALELQPSTSTDRPVtSEPtsqatrgrknrssVKTPEPVVPTAPelQPSTSTDQPVTS 1092
Cdd:PRK10263 494 PVVEETKPARPPLYYFEEVEEKrAREREQLAAWYQPI-PEP-------------VKEPEPIKSSLK--APSVAAVPPVEA 557
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1093 EPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTS-TDRPVT--------PKPTSRTTRSRTNMSS--VKTPETVV----- 1156
Cdd:PRK10263 558 AAAVSPLASGVKKATLATGAAATVAAPVFSLANSgGPRPQVkegigpqlPRPKRIRVPTRRELASygIKLPSQRAaeeka 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1157 ------PTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSS 1230
Cdd:PRK10263 638 reaqrnQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPA 717
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1231 GKTPETL--------------VPTAPKLEPS-----TSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQpstST 1291
Cdd:PRK10263 718 GANPFSLddfefspmkallddGPHEPLFTPIvepvqQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ---QP 794
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1292 DQPVTPEPTSQATRGRT-DRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSS-VKTPETVVPAAPELQP 1369
Cdd:PRK10263 795 QQPVAPQPQYQQPQQPVaPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRpLHKPTTPLPSLDLLTP 874
|
....*...
gi 2462492661 1370 STSTDQPV 1377
Cdd:PRK10263 875 PPSEVEPV 882
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1243-1384 |
1.31e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 43.55 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1243 KLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPT 1322
Cdd:PRK12799 286 KATGLKQIDTHGTVPVAAVTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVA 365
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462492661 1323 APELQASASTDQPVTSEPTSRTTRGRKNRSSvKTPETVVPAAPelqpststDQPVTPEPTSR 1384
Cdd:PRK12799 366 LPAAEPVNMQPQPMSTTETQQSSTGNITSTA-NGPTTSLPAAP--------ASNIPVSPTSR 418
|
|
| COG3456 |
COG3456 |
Predicted component of the type VI protein secretion system, contains a FHA domain [Signal ... |
76-147 |
1.58e-03 |
|
Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442679 [Multi-domain] Cd Length: 402 Bit Score: 43.21 E-value: 1.58e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492661 76 VVGRMPDCSVALPFPS--ISKQHAEIEILawDKAPILRDCgSLNGTQILRPPKVLSPGVSHRLRDQELILFADL 147
Cdd:COG3456 29 TIGRSADCDWVLPDPDrsVSRRHAEIRFR--DGAFCLTDL-STNGTFLNGSDHPLGPGRPVRLRDGDRLRIGDY 99
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
933-1047 |
1.66e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 43.17 E-value: 1.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 933 PKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEP 1012
Cdd:PRK12799 304 VTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQPQPMSTTE 383
|
90 100 110
....*....|....*....|....*....|....*.
gi 2462492661 1013 TSQVTRGrKSRSSVKTPETVVPTALELQ-PSTSTDR 1047
Cdd:PRK12799 384 TQQSSTG-NITSTANGPTTSLPAAPASNiPVSPTSR 418
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1212-1343 |
1.87e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.78 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1212 PVTPEPTSRATrgrkNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTST 1291
Cdd:PRK12799 300 PVAAVTPSSAV----TQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQ 375
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462492661 1292 DQPVTPEPTSQATRGRTDRSSvKTPETVVPTAPELQASAStdqpvtsePTSR 1343
Cdd:PRK12799 376 PQPMSTTETQQSSTGNITSTA-NGPTTSLPAAPASNIPVS--------PTSR 418
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
931-1120 |
1.93e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.93 E-value: 1.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 931 FHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQatrsrtnrssvktPEPVVPTAPELQPSTSTDQPvtS 1010
Cdd:PRK07994 359 FHPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPP-------------PASAPQQAPAVPLPETTSQL--L 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1011 EPTSQVTRgRKSRSSVKTPETVVPTALELQPStSTDRPVTSEPTSQATrgrknrssvkTPEPVVPTAPELQPSTSTDQPV 1090
Cdd:PRK07994 424 AARQQLQR-AQGATKAKKSEPAAASRARPVNS-ALERLASVRPAPSAL----------EKAPAKKEAYRWKATNPVEVKK 491
|
170 180 190
....*....|....*....|....*....|
gi 2462492661 1091 TSEPTYQATrgRKNRSSVKTPEPVVPTAPE 1120
Cdd:PRK07994 492 EPVATPKAL--KKALEHEKTPELAAKLAAE 519
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1123-1372 |
1.99e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.99 E-value: 1.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1123 PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTS-RTTRSRTNMSSVKNPESTVPIap 1201
Cdd:PLN03209 312 PLTPMEELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVpRPLSPYTAYEDLKPPTSPIPT-- 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1202 elPPSTSTEQPVTPEPTSRATRGRKNRSSGKT---PETLVPTAPK-----LEPSTSTDQ---PVTPEPTSQATRGRTNRS 1270
Cdd:PLN03209 390 --PPSSSPASSKSVDAVAKPAEPDVVPSPGSAsnvPEVEPAQVEAkktrpLSPYARYEDlkpPTSPSPTAPTGVSPSVSS 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1271 S---VKTPETVVPTA--PELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTT 1345
Cdd:PLN03209 468 TssvPAVPDTAPATAatDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHH 547
|
250 260
....*....|....*....|....*..
gi 2462492661 1346 RGRKNRssvktPETVVPAAPELQPSTS 1372
Cdd:PLN03209 548 AQPKPR-----PLSPYTMYEDLKPPTS 569
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
1282-1413 |
2.04e-03 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 43.16 E-value: 2.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1282 APEL--QPSTSTDQPVTPEPTSQATrgrtdrssvkTPETVVPTAPELQASaSTDQPVTSEPTSRTTRGRKNRSSVKTPET 1359
Cdd:NF033875 43 AAELdtQPGTTTVQPDNPDPQSGSE----------TPKTAVSEEATVQKD-TTSQPTKVEEVASEKNGAEQSSATPNDTT 111
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2462492661 1360 VVPAAPELQPSTSTDQPVTPEPTSRATRGRtnrssvktPESIVPIAPELQPSTS 1413
Cdd:NF033875 112 NAQQPTVGAEKSAQEQPVVSPETTNEPLGQ--------PTEVAPAENEANKSTS 157
|
|
| FHA_SNIP1_DDL-like |
cd22676 |
forkhead associated (FHA) domain found in Smad nuclear-interacting protein 1 (SNIP1), FHA ... |
54-145 |
2.11e-03 |
|
forkhead associated (FHA) domain found in Smad nuclear-interacting protein 1 (SNIP1), FHA domain-containing protein DDL, and similar proteins; SNIP1 is an FHA domain-containing protein required for pre-mRNA splicing as a component of the spliceosome. It inhibits NF-kappaB signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. It is involved in microRNA (miRNA) biogenesis. SNIP1 is a regulator of the cell cycle and cyclin D1 expression and may be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. This family also includes Arabidopsis thaliana FHA domain-containing protein DDL and similar proteins. DDL, also called protein DAWDLE, is involved in the microRNA (miRNA) and short interfering RNA (siRNA) biogenesis. It may facilitate DCL1 to access or recognize primary miRNAs. DDL binds RNA non-specifically. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438728 [Multi-domain] Cd Length: 111 Bit Score: 39.59 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 54 RLHIFSGAHGPEkdfPLHLGKN---VVGRMPD-CSVALPFPSISKQHAEIEILAWDK----------APILRDCGSLNGT 119
Cdd:cd22676 2 RLYVFKGGEQLE---TIDIHRQsayLIGRDRRvADIPLDHPSCSKQHAVIQFREVEKrnegdvieniRPYIIDLGSTNGT 78
|
90 100
....*....|....*....|....*.
gi 2462492661 120 QILRPPkvLSPGVSHRLRDQELILFA 145
Cdd:cd22676 79 FLNGEK--IEPRRYYELREKDVLKFG 102
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
861-1221 |
2.14e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 43.22 E-value: 2.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 861 QESPDACLPPTVPEAPAPPQKPLNSQSQKhLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPK--PKIR 938
Cdd:pfam03154 168 QTQPPVLQAQSGAASPPSPPPPGTTQAAT-AGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQrlPSPH 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 939 TRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTS-QATRSRTNRSSVKTPEPVVPTAPELQ--PSTSTDQPVTSEPTSQ 1015
Cdd:pfam03154 247 PPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSlQTGPSHMQHPVPPQPFPLTPQSSQSQvpPGPSPAAPGQSQQRIH 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1016 VTRGRKSRSSVKTP-ETVVPTALELQPSTSTDrPVTSEPTSQATRGRKNRSSVKTPEPV-----VPTAPELQP--STSTD 1087
Cdd:pfam03154 327 TPPSQSQLQSQQPPrEQPLPPAPLSMPHIKPP-PTTPIPQLPNPQSHKHPPHLSGPSPFqmnsnLPPPPALKPlsSLSTH 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1088 QPVTSEP-------TYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTap 1160
Cdd:pfam03154 406 HPPSAHPpplqlmpQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPT-- 483
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462492661 1161 elqiSTSTDQPVTPKPTSRTTRSRTNMSSVKNPeSTVPIAPELPPSTSTEQPVTPEPTSRA 1221
Cdd:pfam03154 484 ----STSSAMPGIQPPSSASVSSSGPVPAAVSC-PLPPVQIKEEALDEAEEPESPPPPPRS 539
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
971-1544 |
2.39e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.83 E-value: 2.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 971 PTSQATRS--RTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRP 1048
Cdd:pfam03154 34 PTNEDLRSsgRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSAKRQREKGASDTEEPERATAKKSKTQEISRPNSP 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1049 VTSEPTSQATRGRKNRSSvKTPEPVVPTAPELQPSTST--DQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTS 1126
Cdd:pfam03154 114 SEGEGESSDGRSVNDEGS-SDPKDIDQDNRSTSPSIPSpqDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTT 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1127 TDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSrttrsrtnmssvknPESTVPIAPELPPS 1206
Cdd:pfam03154 193 QAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPS--------------PHPPLQPMTQPPPP 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1207 TSTEQPVTPEPTSRATRGRKNRSSGKTPETL---VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPEtvvPTAP 1283
Cdd:pfam03154 259 SQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMqhpVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQ---SQLQ 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1284 ELQPstSTDQPVTPEPTSQatrgrtdrssvktpetvvptaPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPA 1363
Cdd:pfam03154 336 SQQP--PREQPLPPAPLSM---------------------PHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPP 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1364 APELQP--STSTDQPVTPEPtsratrgrtnrssvkTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEP 1441
Cdd:pfam03154 393 PPALKPlsSLSTHHPPSAHP---------------PPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVP 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1442 VVPTAPEPHPTTSTDQPVTPKLTsratrrktnrssvkTPKPVEPAASDLEPftPTDQSVTPEAIAQGGQSKTLRSSTVRA 1521
Cdd:pfam03154 458 SQSPFPQHPFVPGGPPPITPPSG--------------PPTSTSSAMPGIQP--PSSASVSSSGPVPAAVSCPLPPVQIKE 521
|
570 580
....*....|....*....|...
gi 2462492661 1522 MPVPTTPEFQSPVTTDQPISPEP 1544
Cdd:pfam03154 522 EALDEAEEPESPPPPPRSPSPEP 544
|
|
| FHA_ZEP-like |
cd22702 |
forkhead associated (FHA) domain found in chloroplastic zeaxanthin epoxidase (ZEP) and similar ... |
69-144 |
3.09e-03 |
|
forkhead associated (FHA) domain found in chloroplastic zeaxanthin epoxidase (ZEP) and similar proteins; ZEP, also called protein ABA DEFICIENT 1, ABA1, protein IMPAIRED IN BABA-INDUCED STERILITY 3, protein LOW EXPRESSION OF OSMOTIC STRESS-RESPONSIVE GENES 6, or protein NON-PHOTOCHEMICAL QUENCHING 2, plays an important role in the xanthophyll cycle and abscisic acid (ABA) biosynthesis. It converts zeaxanthin into antheraxanthin and subsequently violaxanthin. ZEP is required for resistance to osmotic and drought stresses, ABA-dependent stomatal closure, seed development and dormancy, modulation of defense gene expression, and disease resistance and non-photochemical quencing (NPQ). The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438754 [Multi-domain] Cd Length: 123 Bit Score: 39.33 E-value: 3.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 69 PLHLGKN-----VVGRMPDC-----SVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQILRPP---KVLSPGVSHR 135
Cdd:cd22702 23 PIRLTRDekqpcIIGSDPHQaisgiSVVIPSPQVSELHARITCK--NGAFFLTDLGSEHGTWINDNEgrrYRAPPNFPVR 100
|
....*....
gi 2462492661 136 LRDQELILF 144
Cdd:cd22702 101 LHPSDVIEF 109
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
952-1220 |
3.23e-03 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 42.36 E-value: 3.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 952 SAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAP-ELQPSTSTDQPVTSEPTSQVTRGRK--SRSSVKT 1028
Cdd:pfam04747 187 SAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPaSVEQVVEQPKVVTEEPHQQAAPQEKknKKNKRKS 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1029 PETVVPTALE--LQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQpvTSEPTYQATRGRKNRS 1106
Cdd:pfam04747 267 ESENVPAASEtpVEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDN--MDFLDFVTAKEEPKDE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1107 SVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETvvptapelqistsTDQPV--TPKPTSRTTRSR 1184
Cdd:pfam04747 345 PAETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESEKV-------------TEQPVesAPAPPQVEQVVE 411
|
250 260 270
....*....|....*....|....*....|....*.
gi 2462492661 1185 TNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSR 1220
Cdd:pfam04747 412 TTPPASENKKKNKKDKKKSESEKAVEEPVQAAPSSK 447
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1146-1413 |
3.44e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.22 E-value: 3.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1146 MSSVKTPETVVPTAPELqisTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPvtpePTSRATRGR 1225
Cdd:PLN03209 297 LSYCKVVEVIAETTAPL---TPMEELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPIEEEP----PQPKAVVPR 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1226 KNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPeLQPSTSTDQPVTP-------- 1297
Cdd:PLN03209 370 PLSPYTAYEDLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEP-AQVEAKKTRPLSPyaryedlk 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1298 EPTSQATRGRTDRSSVKTPETVVPTAPELQ-ASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQP 1376
Cdd:PLN03209 449 PPTSPSPTAPTGVSPSVSSTSSVPAVPDTApATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNE 528
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2462492661 1377 VTP----EPTSRATRGRTNRSSVKTPESIVPIAPELQPSTS 1413
Cdd:PLN03209 529 VVKvgnsAPPTALADEQHHAQPKPRPLSPYTMYEDLKPPTS 569
|
|
| Chi1 |
COG3469 |
Chitinase [Carbohydrate transport and metabolism]; |
950-1179 |
4.16e-03 |
|
Chitinase [Carbohydrate transport and metabolism];
Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 42.05 E-value: 4.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 950 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTP 1029
Cdd:COG3469 1 SSSVSTAASPTAGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1030 ETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNrSSVK 1109
Cdd:COG3469 81 TATAAAAAATSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSG-TETA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1110 TPEPVVPTAPELRPSTSTDRPVTPKPTsrttrsrtnmssvkTPETVVPTAPELQISTSTDQPVTPKPTSR 1179
Cdd:COG3469 160 TGGTTTTSTTTTTTSASTTPSATTTAT--------------ATTASGATTPSATTTATTTGPPTPGLPKH 215
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
1202-1492 |
4.66e-03 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 41.59 E-value: 4.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1202 ELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLV--------PTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVK 1273
Cdd:pfam04747 142 KLQAEKKKEKAVKAEKAEKAEKTKKASTPAPVEEEIVvkkvandrSAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKK 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1274 TPETVVPTAP-ELQPSTSTDQPVTPEPTSQAT--RGRTDRSSVKTPETVVPTAPELQASASTD-QPVTSEPTSRTTRGRK 1349
Cdd:pfam04747 222 KSESEATAAPaSVEQVVEQPKVVTEEPHQQAApqEKKNKKNKRKSESENVPAASETPVEPVVEtTPPASENQKKNKKDKK 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1350 NRSSVKTPETVVPA-APELQPSTSTDQPVTPEPTSraTRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATR 1428
Cdd:pfam04747 302 KSESEKVVEEPVQAeAPKSKKPTADDNMDFLDFVT--AKEEPKDEPAETPAAPVEEVVENVVENVVEKSTTPPATENKKK 379
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1429 CRTNR----SSVKTPEPV--VPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEP 1492
Cdd:pfam04747 380 NKKDKkkseSEKVTEQPVesAPAPPQVEQVVETTPPASENKKKNKKDKKKSESEKAVEEPVQAAPSSKKP 449
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
1264-1548 |
5.16e-03 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 41.91 E-value: 5.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1264 RGRTNRSSVKTPETVVPTAPeLQPSTSTDQPVTPEPTSQAT---RGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1340
Cdd:PHA03369 340 GLKAHNEILKTASLTAPSRV-LAAAAKVAVIAAPQTHTGPAdrqRPQRPDGIPYSVPARSPMTAYPPVPQFCGDPGLVSP 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1341 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRAT-RGRTNRSSVKtpESIVPIAPELQPSTSRNQLVT 1419
Cdd:PHA03369 419 YNPQSPGTSYGPEPVGPVPPQPTNPYVMPISMANMVYPGHPQEHGHeRKRKRGGELK--EELIETLKLVKKLKEEQESLA 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1420 PEPTSRATRCRTNRSS--------VKTPEPVV---PTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAAS 1488
Cdd:PHA03369 497 KELEATAHKSEIKKIAesefknagAKTAAANIepnCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSFTS 576
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492661 1489 DLEPFTPTDQSVTPEAIAqgGQSKTLrSSTVRAMPVPTTPEFQ-------SPVTTDQPISPEPITQP 1548
Cdd:PHA03369 577 TTLAAAAGQGSDTAEALA--GAIETL-LTQASAQPAGLSLPAPavpvnasTPASTPPPLAPQEPPQP 640
|
|
| FHA_RAD53-like_rpt2 |
cd22690 |
second forkhead associated (FHA) domain found in Saccharomyces cerevisiae Serine ... |
53-148 |
5.47e-03 |
|
second forkhead associated (FHA) domain found in Saccharomyces cerevisiae Serine/threonine-protein kinase RAD53 and similar proteins; RAD53, also called CHEK2 homolog, or serine-protein kinase 1 (Spk1), is a nuclear protein kinase that phosphorylates proteins on serine, threonine, and tyrosine. It controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints and prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. It may be involved in the phosphorylation of RPH1. RAD53 contains two FHA domains. This model corresponds to the second one. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438742 [Multi-domain] Cd Length: 105 Bit Score: 38.43 E-value: 5.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 53 GRLHIFSGAHgpeKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPI---LRDCgSLNGTQILRppKVLS 129
Cdd:cd22690 2 GRLKSLNPSY---PDIELTQNTTFIGRSKDCDEEITDPRISKHHCIITRKRSGKGLDdvyVTDT-STNGTFINN--NRLG 75
|
90 100
....*....|....*....|
gi 2462492661 130 PGVSHRLRD-QELILFADLL 148
Cdd:cd22690 76 KGSQSLLQDgDEIVLIWDKN 95
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
860-1185 |
6.79e-03 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 41.20 E-value: 6.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 860 DQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPlSSELEPFHPKPKIRT 939
Cdd:pfam04747 185 DRSAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPASVEQVVEQPKVVTEEP-HQQAAPQEKKNKKNK 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 940 RKSSRMTpFPATSAAPePHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQP--VTSEPTSQVT 1017
Cdd:pfam04747 264 RKSESEN-VPAASETP-VEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDNMdfLDFVTAKEEP 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1018 RGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPV--VPTAPELQPSTSTDQPVTSEPT 1095
Cdd:pfam04747 342 KDEPAETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESEKVTEQPVesAPAPPQVEQVVETTPPASENKK 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1096 YQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPK 1175
Cdd:pfam04747 422 KNKKDKKKSESEKAVEEPVQAAPSSKKPTADDNMDFLDFVTAKPDKSESVEEHIAAPMIVEPAHADEETAAAAEGKKKNK 501
|
330
....*....|
gi 2462492661 1176 PTSRTTRSRT 1185
Cdd:pfam04747 502 KDKKKKESEK 511
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1258-1497 |
6.96e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 41.37 E-value: 6.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1258 PTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1337
Cdd:PRK07003 381 PAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASAD 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1338 SEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPvtPEPTSRATRGRTNRSSVKTPESIVPIAPElQPSTSRNQL 1417
Cdd:PRK07003 461 SRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAP--SAATPAAVPDARAPAAASREDAPAAAAPP-APEARPPTP 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1418 VTPEPTSRAT--------------RCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTpKPV 1483
Cdd:PRK07003 538 AAAAPAARAGgaaaaldvlrnagmRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGA-ARA 616
|
250
....*....|....
gi 2462492661 1484 EPAASDLEPFTPTD 1497
Cdd:PRK07003 617 EQAAESRGAPPPWE 630
|
|
| FHA_Rv1747-like_rpt2 |
cd22737 |
second forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ... |
77-119 |
7.26e-03 |
|
second forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ATP-binding/permease protein Rv1747 and similar proteins; Rv1747 is a putative ATP-binding cassette (ABC) transporter involved in the translocation of an unknown substrate across the membrane. It is required for normal virulent infection by M. tuberculosis. Rv1747 has a cytoplasmic regulatory module consisting of two pThr-interacting forkhead-associated (FHA) domains connected by a conformationally disordered linker with two phospho-acceptor threonines (pThr). Recruitment and phosphorylation of Rv1747 depend on the interaction between its two non-redundant FHA domains and the autophosphorylated form of serine/threonine protein kinase PknF. This model corresponds to the second FHA domain, which has a circularly permuted FHA domain fold with a conserved pThr-binding interface.
Pssm-ID: 439356 [Multi-domain] Cd Length: 93 Bit Score: 37.86 E-value: 7.26e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2462492661 77 VGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGT 119
Cdd:cd22737 25 IGRASDNDIVIPEGSVSRHHATLVPT--PGGTQIRDLRSTNGT 65
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1368-1710 |
7.41e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.31 E-value: 7.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1368 QPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPvvptAP 1447
Cdd:PHA03307 40 QGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSS----PD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1448 EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAiaqggqsktlrsSTVRAMPVPTT 1527
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQA------------ALPLSSPEETA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1528 PEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPK-SQASRNQRWGAVRAAESLTAIPEPaSP 1606
Cdd:PHA03307 184 RAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASsSDSSSSESSGCGWGPENECPLPRP-AP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1607 QLLETPIHASQIQKVE-----PAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQ--PQRGEVSQKTVIIKEEEEDTAEK 1679
Cdd:PHA03307 263 ITLPTRIWEASGWNGPssrpgPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSssSSRESSSSSTSSSSESSRGAAVS 342
|
330 340 350
....*....|....*....|....*....|.
gi 2462492661 1680 PGKEEDvvtpKPGKRKRDQAEEEPNRIPSRS 1710
Cdd:PHA03307 343 PGPSPS----RSPSPSRPPPPADPSSPRKRP 369
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1199-1441 |
8.55e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 41.07 E-value: 8.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1199 IAPELPPSTSTEQPVTPEPTSRATRgrKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRG---RTNRSSVKTP 1275
Cdd:PLN03209 306 IAETTAPLTPMEELLAKIPSQRVPP--KESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPlspYTAYEDLKPP 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1276 ETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSvKTPETVVPTAPELQA---SASTDQPVTSEPTSRTTRGRKNRS 1352
Cdd:PLN03209 384 TSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSAS-NVPEVEPAQVEAKKTrplSPYARYEDLKPPTSPSPTAPTGVS 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1353 SVKTPETVVPAAPELQPSTS-TDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRT 1431
Cdd:PLN03209 463 PSVSSTSSVPAVPDTAPATAaTDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALA 542
|
250
....*....|
gi 2462492661 1432 NRSSVKTPEP 1441
Cdd:PLN03209 543 DEQHHAQPKP 552
|
|
| PHA03255 |
PHA03255 |
BDLF3; Provisional |
1110-1295 |
9.67e-03 |
|
BDLF3; Provisional
Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 39.89 E-value: 9.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1110 TPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS 1189
Cdd:PHA03255 28 GSSTASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVPTTSNASTINVTTKVT 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 1190 VKNPESTvpiapelPPSTSTEQPVTPEPTSRATrgrknrsSGKTPETLVPTAPKLepststdqpvTPEPTSQAtrgrTNR 1269
Cdd:PHA03255 108 AQNITAT-------EAGTGTSTGVTSNVTTRSS-------STTSATTRITNATTL----------APTLSSKG----TSN 159
|
170 180
....*....|....*....|....*..
gi 2462492661 1270 SSVKTPEtvVPTAP-ELQPSTSTDQPV 1295
Cdd:PHA03255 160 ATKTTAE--LPTVPdERQPSLSYGLPL 184
|
|
| FHA_Rv1747-like_rpt1 |
cd22694 |
first forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ... |
76-119 |
9.90e-03 |
|
first forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ATP-binding/permease protein Rv1747 and similar proteins; Rv1747 is a putative ATP-binding cassette (ABC) transporter involved in the translocation of an unknown substrate across the membrane. It is required for normal virulent infection by M. tuberculosis. Rv1747 has a cytoplasmic regulatory module consisting of two pThr-interacting forkhead-associated (FHA) domains connected by a conformationally disordered linker with two phospho-acceptor threonines (pThr). Recruitment and phosphorylation of Rv1747 depend on the interaction between its two non-redundant FHA domains and the autophosphorylated form of serine/threonine protein kinase PknF. This model corresponds to the first FHA domain. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438746 [Multi-domain] Cd Length: 93 Bit Score: 37.31 E-value: 9.90e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 2462492661 76 VVGRMPDCSVALPFPSISKQHAEIEIL--AWdkapILRDCGSLNGT 119
Cdd:cd22694 19 RIGRDPDADVRLDDPRVSRRHALLEFDgdGW----VYTDLGSRNGT 60
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
869-1069 |
9.92e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.01 E-value: 9.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 869 PPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPkiRTRKSSRMTPF 948
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQAS--ARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492661 949 PATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEP-VVPTAPELQPSTSTDQPVTSEPT-SQVTRGRKSRSSV 1026
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADdDPPPWEELPPEFASPAPAQPDAApAGWVAESIPDPAT 531
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2462492661 1027 KTPETVVPTALELQPSTSTDRP-VTSEPTSQATRGRKNRSSVKT 1069
Cdd:PRK12323 532 ADPDDAFETLAPAPAAAPAPRAaAATEPVVAPRPPRASASGLPD 575
|
|
| |
