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Conserved domains on  [gi|2462506899|ref|XP_054191478|]
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flavin-containing monooxygenase 5 isoform X2 [Homo sapiens]

Protein Classification

flavin-binding monooxygenase-like family protein( domain architecture ID 1000557)

flavin-binding monooxygenase-like family protein; such as flavin-containing monooxygenases (FMOs) that catalyze the monooxygenation of a variety of substrates

EC:  1.14.13.-
Gene Ontology:  GO:0004497

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FMO-like super family cl30939
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 3-469 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


The actual alignment was detected with superfamily member pfam00743:

Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 829.04  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899   3 KKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRF-------------------------------------- 44
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFtenveegrasiyksvitntskemscfsdfpfpedypnf 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899  45 -------------------------QTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFP 99
Cdd:pfam00743  81 mhnskfleyfrmfakefdllkyiqfKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 100 GIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTH 179
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 180 FIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDD 259
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 260 IDAVIFATGYSFDFPFLEDS-VKVVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPS 338
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESlVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 339 QSEMMAEISKAQEEIDKRYVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKW 418
Cdd:pfam00743 401 QSEMMAEINKRQEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKW 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462506899 419 DGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAY 469
Cdd:pfam00743 481 EGARNAILTQWDRILKPLKTRVVEKSSSPASSFTLKIFGLPVVLVAIFLIL 531
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 3-469 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 829.04  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899   3 KKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRF-------------------------------------- 44
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFtenveegrasiyksvitntskemscfsdfpfpedypnf 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899  45 -------------------------QTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFP 99
Cdd:pfam00743  81 mhnskfleyfrmfakefdllkyiqfKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 100 GIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTH 179
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 180 FIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDD 259
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 260 IDAVIFATGYSFDFPFLEDS-VKVVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPS 338
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESlVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 339 QSEMMAEISKAQEEIDKRYVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKW 418
Cdd:pfam00743 401 QSEMMAEINKRQEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKW 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462506899 419 DGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAY 469
Cdd:pfam00743 481 EGARNAILTQWDRILKPLKTRVVEKSSSPASSFTLKIFGLPVVLVAIFLIL 531
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-365 1.81e-54

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 187.38  E-value: 1.81e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899   1 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLW-------------------------------------- 42
Cdd:COG2072     4 TEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWrdnrypglrldtpshlyslpffpnwsddpdfptgdeil 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899  43 ----------------RFQTTVCSVKKQPDfatSGQWEVVTESEGKKEmnvFDGVMVCTGHHTNAHLPleSFPGIEKFKG 106
Cdd:COG2072    84 ayleayadkfglrrpiRFGTEVTSARWDEA---DGRWTVTTDDGETLT---ARFVVVATGPLSRPKIP--DIPGLEDFAG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 107 QYFHSRDYKNPEGFTGKRViiigignsggDLAVEISQTAKQVFLSTRRGAWILNRVgDYGyPADVLFSSRLTHFIWKICG 186
Cdd:COG2072   156 EQLHSADWRNPVDLAGKRVlvvgtgasavQIAPELARVAAHVTVFQRTPPWVLPRP-NYD-PERGRPANYLGLEAPPALN 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 187 QSLANKYLEKKINQRFDHEMFG-LKPKHRALSQHPTLNDDLPNRIISGLVK-VKGNVKEFTETAAIFEDGSREdDIDAVI 264
Cdd:COG2072   234 RRDARAWLRRLLRAQVKDPELGlLTPDYPPGCKRPLLSTDYYEALRRGNVElVTGGIERITEDGVVFADGTEH-EVDVIV 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 265 FATGYSFDFPFLeDSVKVV----KNKISLYKKVFPPNLerPTLAIIGLIQPLG--AIMPISELQGRWATQVFKGLKTLPS 338
Cdd:COG2072   313 WATGFRADLPWL-APLDVRgrdgRSGPRAYLGVVVPGF--PNLFFLGPNSPSGhsSLTLGAERQARYIARLIAHMRRRGA 389

                         410       420
                  ....*....|....*....|....*..
gi 2462506899 339 QSemMAEISKAQEEIDKRYVESQRHTI 365
Cdd:COG2072   390 AA--IEVRPEAEDAFNARLQRRAARTV 414
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 32-376 1.48e-22

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 99.94  E-value: 1.48e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899  32 FERTDDIGGLWRFQTTVcsVKKQPdfaTSGQWEVVTE-SEGKKEMNVFDGVMVCTGHHTN---AHLPlesfpGIEKFKGQ 107
Cdd:PLN02172  120 FAREFKIEEMVRFETEV--VRVEP---VDGKWRVQSKnSGGFSKDEIFDAVVVCNGHYTEpnvAHIP-----GIKSWPGK 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 108 YFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRrgawilnrvgdygypadvlfsSRLTHFIWKI-CG 186
Cdd:PLN02172  190 QIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASR---------------------ASESDTYEKLpVP 248

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 187 QSlaNKYLEKKINqrFDHEmfglkpkhralsqhptlnddlpnriisglvkvkgnvkeftETAAIFEDGsREDDIDAVIFA 266
Cdd:PLN02172  249 QN--NLWMHSEID--TAHE----------------------------------------DGSIVFKNG-KVVYADTIVHC 283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 267 TGYSFDFPFLEDS--VKVVKNKIS-LYKKVFPPNLErPTLAIIGLiQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMM 343
Cdd:PLN02172  284 TGYKYHFPFLETNgyMRIDENRVEpLYKHVFPPALA-PGLSFIGL-PAMGIQFVMFEIQSKWVAAVLSGRVTLPSEDKMM 361

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 2462506899 344 AEISKAQEEID-----KRYVesqrHT---IQGDYIDTMEEL 376
Cdd:PLN02172  362 EDINAWYASLEalgipKRYT----HKlgkIQSEYLNWIAEE 398
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 3-469 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 829.04  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899   3 KKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRF-------------------------------------- 44
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFtenveegrasiyksvitntskemscfsdfpfpedypnf 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899  45 -------------------------QTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFP 99
Cdd:pfam00743  81 mhnskfleyfrmfakefdllkyiqfKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 100 GIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTH 179
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 180 FIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDD 259
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 260 IDAVIFATGYSFDFPFLEDS-VKVVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPS 338
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESlVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 339 QSEMMAEISKAQEEIDKRYVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKW 418
Cdd:pfam00743 401 QSEMMAEINKRQEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKW 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462506899 419 DGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAY 469
Cdd:pfam00743 481 EGARNAILTQWDRILKPLKTRVVEKSSSPASSFTLKIFGLPVVLVAIFLIL 531
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-365 1.81e-54

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 187.38  E-value: 1.81e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899   1 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLW-------------------------------------- 42
Cdd:COG2072     4 TEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWrdnrypglrldtpshlyslpffpnwsddpdfptgdeil 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899  43 ----------------RFQTTVCSVKKQPDfatSGQWEVVTESEGKKEmnvFDGVMVCTGHHTNAHLPleSFPGIEKFKG 106
Cdd:COG2072    84 ayleayadkfglrrpiRFGTEVTSARWDEA---DGRWTVTTDDGETLT---ARFVVVATGPLSRPKIP--DIPGLEDFAG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 107 QYFHSRDYKNPEGFTGKRViiigignsggDLAVEISQTAKQVFLSTRRGAWILNRVgDYGyPADVLFSSRLTHFIWKICG 186
Cdd:COG2072   156 EQLHSADWRNPVDLAGKRVlvvgtgasavQIAPELARVAAHVTVFQRTPPWVLPRP-NYD-PERGRPANYLGLEAPPALN 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 187 QSLANKYLEKKINQRFDHEMFG-LKPKHRALSQHPTLNDDLPNRIISGLVK-VKGNVKEFTETAAIFEDGSREdDIDAVI 264
Cdd:COG2072   234 RRDARAWLRRLLRAQVKDPELGlLTPDYPPGCKRPLLSTDYYEALRRGNVElVTGGIERITEDGVVFADGTEH-EVDVIV 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 265 FATGYSFDFPFLeDSVKVV----KNKISLYKKVFPPNLerPTLAIIGLIQPLG--AIMPISELQGRWATQVFKGLKTLPS 338
Cdd:COG2072   313 WATGFRADLPWL-APLDVRgrdgRSGPRAYLGVVVPGF--PNLFFLGPNSPSGhsSLTLGAERQARYIARLIAHMRRRGA 389

                         410       420
                  ....*....|....*....|....*..
gi 2462506899 339 QSemMAEISKAQEEIDKRYVESQRHTI 365
Cdd:COG2072   390 AA--IEVRPEAEDAFNARLQRRAARTV 414
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 32-376 1.48e-22

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 99.94  E-value: 1.48e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899  32 FERTDDIGGLWRFQTTVcsVKKQPdfaTSGQWEVVTE-SEGKKEMNVFDGVMVCTGHHTN---AHLPlesfpGIEKFKGQ 107
Cdd:PLN02172  120 FAREFKIEEMVRFETEV--VRVEP---VDGKWRVQSKnSGGFSKDEIFDAVVVCNGHYTEpnvAHIP-----GIKSWPGK 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 108 YFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRrgawilnrvgdygypadvlfsSRLTHFIWKI-CG 186
Cdd:PLN02172  190 QIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASR---------------------ASESDTYEKLpVP 248

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 187 QSlaNKYLEKKINqrFDHEmfglkpkhralsqhptlnddlpnriisglvkvkgnvkeftETAAIFEDGsREDDIDAVIFA 266
Cdd:PLN02172  249 QN--NLWMHSEID--TAHE----------------------------------------DGSIVFKNG-KVVYADTIVHC 283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462506899 267 TGYSFDFPFLEDS--VKVVKNKIS-LYKKVFPPNLErPTLAIIGLiQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMM 343
Cdd:PLN02172  284 TGYKYHFPFLETNgyMRIDENRVEpLYKHVFPPALA-PGLSFIGL-PAMGIQFVMFEIQSKWVAAVLSGRVTLPSEDKMM 361

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 2462506899 344 AEISKAQEEID-----KRYVesqrHT---IQGDYIDTMEEL 376
Cdd:PLN02172  362 EDINAWYASLEalgipKRYT----HKlgkIQSEYLNWIAEE 398
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-41 5.90e-05

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 45.21  E-value: 5.90e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2462506899   3 KKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGL 41
Cdd:COG1232     1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGL 39
PRK07233 PRK07233
hypothetical protein; Provisional
 5-41 9.48e-05

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 44.49  E-value: 9.48e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2462506899   5 RIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGL 41
Cdd:PRK07233    1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGL 37
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 2-44 2.56e-04

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 43.23  E-value: 2.56e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2462506899   2 TKKRIAVIGGGVSGLSsikcCVEE----GLEPVCFERTDDIGGLWRF 44
Cdd:PRK12810  142 TGKKVAVVGSGPAGLA----AADQlaraGHKVTVFERADRIGGLLRY 184
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
8-43 6.15e-04

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 38.28  E-value: 6.15e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462506899   8 VIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWR 43
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAY 36
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
1-18 6.46e-04

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 42.03  E-value: 6.46e-04
                          10
                  ....*....|....*...
gi 2462506899   1 MTKKRIAVIGGGVSGLSS 18
Cdd:COG2907     1 MARMRIAVIGSGISGLTA 18
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 2-44 1.84e-03

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 40.50  E-value: 1.84e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2462506899   2 TKKRIAVIGGGVSGLSsikcC----VEEGLEPVCFERTDDIGGLWRF 44
Cdd:COG0493   120 TGKKVAVVGSGPAGLA----AayqlARAGHEVTVFEALDKPGGLLRY 162
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-40 2.12e-03

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 40.22  E-value: 2.12e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2462506899   1 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGG 40
Cdd:COG3349     1 MMPPRVVVVGGGLAGLAAAVELAEAGFRVTLLEARPRLGG 40
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 2-44 2.38e-03

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 40.50  E-value: 2.38e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2462506899   2 TKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRF 44
Cdd:PRK12769  326 SDKRVAIIGAGPAGLACADVLARNGVAVTVYDRHPEIGGLLTF 368
PRK07208 PRK07208
hypothetical protein; Provisional
 1-44 4.03e-03

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 39.49  E-value: 4.03e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462506899   1 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGL--------WRF 44
Cdd:PRK07208    2 TNKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGIsrtvtykgNRF 53
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
1-50 4.56e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 39.46  E-value: 4.56e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462506899   1 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWR-----FQTTVCS 50
Cdd:COG1148   138 PVNKRALVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGRAAqlhktFPGLDCP 192
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
230-286 5.57e-03

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 38.74  E-value: 5.57e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462506899 230 IISGLVKVKGN--VKEFTETAAI----FEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNK 286
Cdd:pfam13738 213 VKNGKIKAHFNaeVKEITEVDVSykvhTEDGRKVTSNDDPILATGYHPDLSFLKKGLFELDED 275
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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