NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2462510636|ref|XP_054193277|]
View 

sushi domain-containing protein 4 isoform X2 [Homo sapiens]

Protein Classification

CCP domain-containing protein( domain architecture ID 13269567)

CCP domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PHA02639 super family cl31493
EEV host range protein; Provisional
 114-295 8.26e-14

EEV host range protein; Provisional


The actual alignment was detected with superfamily member PHA02639:

Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 72.00  E-value: 8.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 114 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLgWiPSDNSICVQEDCR-IPQIEDAEIHNK 192
Cdd:PHA02639   22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W-SNKAPFCMLKECNdPPSIINGKIYNK 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 193 --TYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRPlASSNGYVNISELQTSFPVGTVISYRC 267
Cdd:PHA02639  100 reMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP-ALQNGYINGIPSNKKFYYKTRVGFSC 178

                         170       180
                  ....*....|....*....|....*...
gi 2462510636 268 FPGFKLDGSAYLECLQNLIWSSSPPRCL 295
Cdd:PHA02639  179 KSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 302-356 3.42e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 3.42e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462510636  302 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 356
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
 
Name Accession Description Interval E-value
PHA02639 PHA02639
EEV host range protein; Provisional
 114-295 8.26e-14

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 72.00  E-value: 8.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 114 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLgWiPSDNSICVQEDCR-IPQIEDAEIHNK 192
Cdd:PHA02639   22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W-SNKAPFCMLKECNdPPSIINGKIYNK 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 193 --TYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRPlASSNGYVNISELQTSFPVGTVISYRC 267
Cdd:PHA02639  100 reMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP-ALQNGYINGIPSNKKFYYKTRVGFSC 178

                         170       180
                  ....*....|....*....|....*...
gi 2462510636 268 FPGFKLDGSAYLECLQNLIWSSSPPRCL 295
Cdd:PHA02639  179 KSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 237-294 9.22e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 9.22e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462510636 237 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 294
Cdd:cd00033     1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 237-294 1.73e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 1.73e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462510636  237 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 294
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
247-294 3.52e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.89  E-value: 3.52e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2462510636 247 YVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 294
Cdd:pfam00084   9 NGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 302-356 3.42e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 3.42e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462510636  302 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 356
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 302-353 7.56e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 7.56e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462510636 302 CPLPPMVSHGDFVCHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 353
Cdd:cd00033     1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
302-353 4.74e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.03  E-value: 4.74e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462510636 302 CPLPPMVSHGDFVChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 353
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
 
Name Accession Description Interval E-value
PHA02639 PHA02639
EEV host range protein; Provisional
 114-295 8.26e-14

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 72.00  E-value: 8.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 114 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLgWiPSDNSICVQEDCR-IPQIEDAEIHNK 192
Cdd:PHA02639   22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W-SNKAPFCMLKECNdPPSIINGKIYNK 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 193 --TYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRPlASSNGYVNISELQTSFPVGTVISYRC 267
Cdd:PHA02639  100 reMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP-ALQNGYINGIPSNKKFYYKTRVGFSC 178

                         170       180
                  ....*....|....*....|....*...
gi 2462510636 268 FPGFKLDGSAYLECLQNLIWSSSPPRCL 295
Cdd:PHA02639  179 KSGFDLVGEKYSTCNINATWFPSIPTCV 206
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 114-295 1.67e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 67.76  E-value: 1.67e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 114 CADPGIPENGfRTPSGGVFFeGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPsDNSICVQEDCRIPQIEDAEIHN-- 191
Cdd:PHA02927   86 CPSPRDIDNG-QLDIGGVDF-GSSITYSCNSGYQLIGESKSYCELGSTGSMVWNP-EAPICESVKCQSPPSISNGRHNgy 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 192 -KTYRHGEKLIITCHEGFKIrypdLHNMVSLCrDDGTWNNLPICQ--GCLRPlASSNGYVNiSELQTSFPVGTVISYRCF 268
Cdd:PHA02927  163 eDFYTDGSVVTYSCNSGYSL----IGNSGVLC-SGGEWSDPPTCQivKCPHP-TISNGYLS-SGFKRSYSYNDNVDFKCK 235

                         170       180
                  ....*....|....*....|....*..
gi 2462510636 269 PGFKLDGSAYLECLQNLIWSSSPPRCL 295
Cdd:PHA02927  236 YGYKLSGSSSSTCSPGNTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 237-294 9.22e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 9.22e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462510636 237 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 294
Cdd:cd00033     1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 237-294 1.73e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 1.73e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462510636  237 CLRPLASSNGYVNISelQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 294
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 191-353 5.66e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 60.05  E-value: 5.66e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 191 NKTYRHGEKLIITCHEGFkiRYPDLHNMVSLCRDDG-TWNNLPICQGCLRPLASSNGYVNISELQtsfpVGTVISYRCFP 269
Cdd:PHA02927   41 NANYNIGDTIEYLCLPGY--RKQKMGPIYAKCTGTGwTLFNQCIKRRCPSPRDIDNGQLDIGGVD----FGSSITYSCNS 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 270 GFKLDGSAYLEC----LQNLIWSSSPPRClalEAQVCPLPPMVSHGDfvcHPRPCERYNHGTVVEFYCDPGYSLTSDYKy 345
Cdd:PHA02927  115 GYQLIGESKSYCelgsTGSMVWNPEAPIC---ESVKCQSPPSISNGR---HNGYEDFYTDGSVVTYSCNSGYSLIGNSG- 187


                  ....*...
gi 2462510636 346 ITCQYGEW 353
Cdd:PHA02927  188 VLCSGGEW 195
PHA02817 PHA02817
EEV Host range protein; Provisional
 172-294 6.24e-10

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 59.57  E-value: 6.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 172 SICVQEDCRIP-QIEDAEIHNK--TYRHGEKLIITCHEGFK-IRYPDLHNMVSLCRDDGTWN-NLPICQ--GCLRPlASS 244
Cdd:PHA02817   17 SLCDLNKCCYPpSIKNGYIYNKktEYNIGSNVTFFCGNNTRgVRYTLVGEKNIICEKDGKWNkEFPVCKiiRCRFP-ALQ 95

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462510636 245 NGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 294
Cdd:PHA02817   96 NGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
Sushi pfam00084
Sushi repeat (SCR repeat);
247-294 3.52e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.89  E-value: 3.52e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2462510636 247 YVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 294
Cdd:pfam00084   9 NGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 302-356 3.42e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 3.42e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462510636  302 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 356
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 302-353 7.56e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 7.56e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462510636 302 CPLPPMVSHGDFVCHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 353
Cdd:cd00033     1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 114-159 1.53e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.23  E-value: 1.53e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2462510636 114 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKH 159
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN 46
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 114-157 9.67e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.98  E-value: 9.67e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2462510636  114 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCL 157
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL 44
PHA02639 PHA02639
EEV host range protein; Provisional
 237-355 1.18e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.43  E-value: 1.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 237 CLRPLASSNGYvnISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQ---NLIWSSSPPRCLALEaqvCPLPPMVSHGDf 313
Cdd:PHA02639   22 CDKPDDISNGF--ITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKdknNAIWSNKAPFCMLKE---CNDPPSIINGK- 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2462510636 314 VCHPRpcERYNHGTVVEFYCDP----GYSLTSDYKYITCQYGEWFP 355
Cdd:PHA02639   96 IYNKR--EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKP 139
PHA02831 PHA02831
EEV host range protein; Provisional
 161-295 1.36e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 49.99  E-value: 1.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 161 NGTlgWipSDNSICV-QEDCRIP-QIEDAEIHNKT--YRHGEKLIITCHEGFKIRYPDLHNMVSLCRDdGTW-NNLPICQ 235
Cdd:PHA02831   63 NGS--W--STKNMCIgKRNCKDPvTILNGYIKNKKdqYSFGDSVTYACKVNKLEKYSIVGNETVKCIN-KQWvPKYPVCK 137

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462510636 236 --GCLRPlASSNGYVNIseLQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCL 295
Cdd:PHA02831  138 liRCKYP-ALQNGFLNV--FEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCV 196
Sushi pfam00084
Sushi repeat (SCR repeat);
302-353 4.74e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.03  E-value: 4.74e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462510636 302 CPLPPMVSHGDFVChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 353
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
114-161 5.60e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 5.60e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2462510636 114 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFN 161
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT 48
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 111-355 8.56e-06

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 47.34  E-value: 8.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 111 LQVCADPGIP-----ENGFRTPSGGVFFEGSVARFHCQDGFKLK--GATKRLClkhfNGTlGWIPSDNsiCVQEDCRIPQ 183
Cdd:PHA02927   18 LSCCTIPSRPinmkfKNSVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKC----TGT-GWTLFNQ--CIKRRCPSPR 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 184 -IEDAEIHNKTYRHGEKLIITCHEGFKIrypdLHNMVSLCRDDGT----WN-NLPICQG--CLRPLASSNGYVNISElqT 255
Cdd:PHA02927   91 dIDNGQLDIGGVDFGSSITYSCNSGYQL----IGESKSYCELGSTgsmvWNpEAPICESvkCQSPPSISNGRHNGYE--D 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 256 SFPVGTVISYRCFPGFKLDGSAYLEClQNLIWSSsPPRCLALEaqvCPlPPMVSHGDFVCHPRpcERYNHGTVVEFYCDP 335
Cdd:PHA02927  165 FYTDGSVVTYSCNSGYSLIGNSGVLC-SGGEWSD-PPTCQIVK---CP-HPTISNGYLSSGFK--RSYSYNDNVDFKCKY 236

                         250       260
                  ....*....|....*....|.
gi 2462510636 336 GYSLTSDYKYiTCQYGE-WFP 355
Cdd:PHA02927  237 GYKLSGSSSS-TCSPGNtWQP 256
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 149-304 1.16e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 47.39  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 149 KGATKRLCLKHFNGTLGWipSDNSICVQEDCRIPQIEDAEIH--NKTYRHGEKLIITCHEGFKIRYPDLHNMVSlcrddG 226
Cdd:PHA02954  102 KDETKYFRCEEKNGNTSW--NDTVTCPNAECQPLQLEHGSCQpvKEKYSFGEHITINCDVGYEVIGASYISCTA-----N 174

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462510636 227 TWNNLPICQGCLRPLASSNGYVNISelqtSFPVGTVISYRCFPGFKLDGSAYLECLQNLiWSSSPPRCLALEAQVCPL 304
Cdd:PHA02954  175 SWNVIPSCQQKCDIPSLSNGLISGS----TFSIGGVIHLSCKSGFTLTGSPSSTCIDGK-WNPVLPICVRSNEEFDPV 247
PHA02831 PHA02831
EEV host range protein; Provisional
 172-363 1.50e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.91  E-value: 1.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 172 SICV--QEDCRIPQIEDAEihNKTYRHGEKLIITCHEGFkirypdlhNMVSLCRDDGTWNNLPICQG---CLRPLASSNG 246
Cdd:PHA02831   18 CICVfnKNDAKYSNVDSYE--NKVYEENENLEYKCNNNF--------DKVFVTCNNGSWSTKNMCIGkrnCKDPVTILNG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 247 YVNISELQTSFpvGTVISYRC----FPGFKLDGSAYLECLqNLIWSSSPPRCLALEAQVcplpPMVSHGDFVCHPRpceR 322
Cdd:PHA02831   88 YIKNKKDQYSF--GDSVTYACkvnkLEKYSIVGNETVKCI-NKQWVPKYPVCKLIRCKY----PALQNGFLNVFEK---K 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2462510636 323 YNHGTVVEFYCDPGY----SLTSdykyiTCQYGE-WFPSYQvYCIK 363
Cdd:PHA02831  158 FYYGDIVNFKCKKGFillgSSVS-----TCDINSiWYPGIP-KCVK 197
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 182-234 1.54e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.74  E-value: 1.54e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462510636  182 PQIEDAEI--HNKTYRHGEKLIITCHEGFKIRYPDlhnmVSLCRDDGTWNN-LPIC 234
Cdd:smart00032   5 PDIENGTVtsSSGTYSYGDTVTYSCDPGYTLIGSS----TITCLENGTWSPpPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 182-235 7.23e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 35.13  E-value: 7.23e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462510636 182 PQIEDAEI--HNKTYRHGEKLIITCHEGFKIRYPDlhnmVSLCRDDGTWNN-LPICQ 235
Cdd:cd00033     5 PVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSS----TITCTENGGWSPpPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
179-234 8.38e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 34.78  E-value: 8.38e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510636 179 CRIPQ-IEDAEIH--NKTYRHGEKLIITCHEGFkiRYPDlhNMVSLCRDDGTWNNL-PIC 234
Cdd:pfam00084   1 CPPPPdIPNGKVSatKNEYNYGASVSYECDPGY--RLVG--SPTITCQEDGTWSPPfPEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH