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Conserved domains on  [gi|2462510937|ref|XP_054193424|]
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enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X9 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 1-196 9.33e-63

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02600:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 251  Bit Score: 194.64  E-value: 9.33e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR----------- 69
Cdd:PLN02600   10 LDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRstfsslealsi 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 -----------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PLN02600   90 ptiavvegaalggglelALSCDLricgeeavfglpetglaiipgaGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 190
Cdd:PLN02600  170 VNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKRK 245


                  ....*.
gi 2462510937 191 PKFVGK 196
Cdd:PLN02600  246 PVYTGK 251
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
 1-196 9.33e-63

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 194.64  E-value: 9.33e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR----------- 69
Cdd:PLN02600   10 LDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRstfsslealsi 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 -----------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PLN02600   90 ptiavvegaalggglelALSCDLricgeeavfglpetglaiipgaGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 190
Cdd:PLN02600  170 VNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKRK 245


                  ....*.
gi 2462510937 191 PKFVGK 196
Cdd:PLN02600  246 PVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 1-189 7.96e-43

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 143.77  E-value: 7.96e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN------ 73
Cdd:COG1024    14 LNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFRalrrlp 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  74 --------------------------------------------DIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 109
Cdd:COG1024    93 kpviaavngaalggglelalacdlriaaedarfglpevrlglipGGGGTQRLPRLVGLARAKELLLTGRRIDAEEALELG 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 110 LVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKR 189
Cdd:COG1024   173 LVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLEKR 248
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 1-196 4.90e-28

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 105.52  E-value: 4.90e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVF-------VQRLR---- 69
Cdd:pfam00378  11 LNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYrenvldlWTLLYtcpk 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 ---------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:pfam00378  90 pviaavngyaigggcelalacdiiiaadnasfglnetklGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 190
Cdd:pfam00378 170 VDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEKRK 245


                  ....*.
gi 2462510937 191 PKFVGK 196
Cdd:pfam00378 246 PPWEDQ 251
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 1-135 8.82e-27

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 100.71  E-value: 8.82e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGV---------FVQRLR-- 69
Cdd:cd06558    14 LNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAGEEArafirelqeLLRALLrl 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 -----------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 108
Cdd:cd06558    93 pkpviaavngaalggglelalacdiriaaedakfglpevklGLVPGGGGTQRLPRLVGPARARELLLTGRRISAEEALEL 172

                         170       180
                  ....*....|....*....|....*..
gi 2462510937 109 GLVNHAVaqneEGDAAYQRARALAQEI 135
Cdd:cd06558   173 GLVDEVV----PDEELLAAALELARRL 195
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 1-152 1.09e-06

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 48.29  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGAD---------LKEREQMS-EAEVGVF-VQR- 67
Cdd:TIGR02441  28 IDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADiqmiaacktAQEVTQLSqEGQEMFErIEKs 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  68 -----------------------------------------LRGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 106
Cdd:TIGR02441 108 qkpivaaisgsclggglelalachyriatkdrktllglpevMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAK 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2462510937 107 VLGLVNHAVAQNEEG-DAAYQRARALAQEILPQAPIAVRLGKVAIDR 152
Cdd:TIGR02441 188 KMGIVDQLVDPLGPGlKPAEENTIEYLEEVAVKFAQGLANGKLSINR 234
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
 1-196 9.33e-63

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 194.64  E-value: 9.33e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR----------- 69
Cdd:PLN02600   10 LDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRstfsslealsi 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 -----------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PLN02600   90 ptiavvegaalggglelALSCDLricgeeavfglpetglaiipgaGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 190
Cdd:PLN02600  170 VNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKRK 245


                  ....*.
gi 2462510937 191 PKFVGK 196
Cdd:PLN02600  246 PVYTGK 251
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 1-196 4.50e-56

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 178.00  E-value: 4.50e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDI----- 75
Cdd:PRK07657   19 LNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTMEMVeqlpq 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  76 ---------------------------------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PRK07657   99 pviaaingialggglelalacdfriaaesaslgltettlaiipgaGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEIGL 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 190
Cdd:PRK07657  179 VEFVVPAHL----LEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTKDRLEGLQAFKEKRK 254


                  ....*.
gi 2462510937 191 PKFVGK 196
Cdd:PRK07657  255 PMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 1-189 7.96e-43

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 143.77  E-value: 7.96e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN------ 73
Cdd:COG1024    14 LNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFRalrrlp 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  74 --------------------------------------------DIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 109
Cdd:COG1024    93 kpviaavngaalggglelalacdlriaaedarfglpevrlglipGGGGTQRLPRLVGLARAKELLLTGRRIDAEEALELG 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 110 LVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKR 189
Cdd:COG1024   173 LVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLEKR 248
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
1-196 1.47e-35

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 125.24  E-value: 1.47e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAE---VGVFVQRL-RGLMN--- 73
Cdd:PRK05809   19 INRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEgrkFGLLGNKVfRKLENldk 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  74 ---------------------DI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PRK05809   99 pviaaingfalgggcelsmacDIriasekakfgqpevglgitpgfGGTQRLARIVGPGKAKELIYTGDMINAEEALRIGL 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAQNEEGDAAYqrarALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 190
Cdd:PRK05809  179 VNKVVEPEKLMEEAK----ALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGMTAFVEKRE 254


                  ....*.
gi 2462510937 191 PKFVGK 196
Cdd:PRK05809  255 KNFKNK 260
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 1-196 8.69e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 115.35  E-value: 8.69e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE------REQMSEAEVGVFVQRLR----- 69
Cdd:PRK06688   20 INRPDKKNALTAAMYQALADALEAAATDPAVRVVVLT-GAGRAFSAGGDIKDfpkappKPPDELAPVNRFLRAIAalpkp 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 --------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLV 111
Cdd:PRK06688   99 vvaavngpavgvgvslalacdlvyasesakfslpfaklGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSAEEALRIGLV 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 112 NHAVAqNEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTP 191
Cdd:PRK06688  179 NRVVP-AAELDAE---ADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATAFIEKRKP 254


                  ....*
gi 2462510937 192 KFVGK 196
Cdd:PRK06688  255 DFTGF 259
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 1-196 4.90e-28

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 105.52  E-value: 4.90e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVF-------VQRLR---- 69
Cdd:pfam00378  11 LNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYrenvldlWTLLYtcpk 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 ---------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:pfam00378  90 pviaavngyaigggcelalacdiiiaadnasfglnetklGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 190
Cdd:pfam00378 170 VDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEKRK 245


                  ....*.
gi 2462510937 191 PKFVGK 196
Cdd:pfam00378 246 PPWEDQ 251
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 1-196 2.89e-27

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 103.69  E-value: 2.89e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEreqMSEAEVGVFV--------QRLR--- 69
Cdd:PRK09674   17 LNRPEARNALNNALLTQLVNELEAAATDTSIGVCVIT-GNARFFAAGADLNE---MAEKDLAATLndprpqlwQRLQafn 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 ----------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 109
Cdd:PRK09674   93 kpliaavngyalgagcelallcdiviagenarfglpeitlGIMPGAGGTQRLIRSVGKSLASQMVLTGESITAQQAQQAG 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 110 LVNHaVAQNEegdAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKR 189
Cdd:PRK09674  173 LVSE-VFPPE---LTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGISAFLEKR 248


                  ....*..
gi 2462510937 190 TPKFVGK 196
Cdd:PRK09674  249 TPDFKGR 255
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 1-135 8.82e-27

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 100.71  E-value: 8.82e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGV---------FVQRLR-- 69
Cdd:cd06558    14 LNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAGEEArafirelqeLLRALLrl 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 -----------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 108
Cdd:cd06558    93 pkpviaavngaalggglelalacdiriaaedakfglpevklGLVPGGGGTQRLPRLVGPARARELLLTGRRISAEEALEL 172

                         170       180
                  ....*....|....*....|....*..
gi 2462510937 109 GLVNHAVaqneEGDAAYQRARALAQEI 135
Cdd:cd06558   173 GLVDEVV----PDEELLAAALELARRL 195
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 1-196 1.47e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 99.36  E-value: 1.47e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEV------------------- 61
Cdd:PRK08138   23 LNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVL-TGGEKVFAAGADIKEFATAGAIEMylrhteryweaiaqcpkpv 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  62 ---------------------------GVFVQ---RLrGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLV 111
Cdd:PRK08138  102 iaavngyalgggcelamhadiivagesASFGQpeiKV-GLMPGAGGTQRLVRAVGKFKAMRMALTGCMVPAPEALAIGLV 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 112 NHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTP 191
Cdd:PRK08138  181 SEVV----EDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQKEGMDAFLEKRKP 256


                  ....*
gi 2462510937 192 KFVGK 196
Cdd:PRK08138  257 AYKGK 261
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 2-196 6.80e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 97.40  E-value: 6.80e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   2 NRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE------REQMSE-AEVG-VFVQRLR---- 69
Cdd:PRK07658   18 NHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIH-GEGRFFSAGADIKEftsvteAEQATElAQLGqVTFERVEkfsk 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 ---------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PRK07658   96 pviaaihgaalggglelamschirfatesaklglpelnlGLIPGFAGTQRLPRYVGKAKALEMMLTSEPITGAEALKWGL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 190
Cdd:PRK07658  176 VNGVFPEET----LLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEGVQAFLEKRK 251


                  ....*.
gi 2462510937 191 PKFVGK 196
Cdd:PRK07658  252 PSFSGK 257
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 1-193 7.01e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 92.03  E-value: 7.01e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEV--GVF------VQRLR--- 69
Cdd:PRK05862   19 LNRPKALNALNDALMDELGAALAAFDADEGIGAIVI-TGSEKAFAAGADIKEMADLSFMDVykGDYitnwekVARIRkpv 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 ---------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVN 112
Cdd:PRK05862   98 iaavagyalgggcelAMMCDIiiaadtakfgqpeiklgvlpgmGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERAGLVS 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 113 HAVAQNEEGDAAYQRARALAQEILPqapiAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPK 192
Cdd:PRK05862  178 RVVPADKLLDEALAAATTIASFSLP----AVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMAAFVEKRKPV 253


                  .
gi 2462510937 193 F 193
Cdd:PRK05862  254 F 254
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 69-196 1.46e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 88.56  E-value: 1.46e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  69 RGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQnEEGDAAyqrARALAQEILPQAPIAVRLGKV 148
Cdd:PRK06494  134 VGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREGLELGFVNEVVPA-GELLAA---AERWADDILACSPLSIRASKQ 209

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462510937 149 AIDRGTEVDIASGMAIEGMCYAQN--IPTRDRLEGMAAFREKRTPKFVGK 196
Cdd:PRK06494  210 AVYRGLEVSLEEAITAQRDYPAVEarRASQDYIEGPKAFAEKRPPRWKGR 259
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
1-193 2.35e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 88.28  E-value: 2.35e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKE------------------REQMSEAEVG 62
Cdd:PRK05980   18 LNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEfsasvaagadvalrdfvrRGQAMTARLE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  63 VFVQRLRGLMNDI------------------------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAH 106
Cdd:PRK05980   98 AFPKPVIAAVNGLafgggceiteavhlaiaseralfakpeirlgmpptfGGTQRLPRLAGRKRALELLLTGDAFSAERAL 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 107 VLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 186
Cdd:PRK05980  178 EIGLVNAVVPH----EELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAGSADLREGLAAWI 253


                  ....*..
gi 2462510937 187 EKRTPKF 193
Cdd:PRK05980  254 ERRRPAY 260
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 1-187 2.74e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 87.72  E-value: 2.74e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE--------REQMSEAEVGVFVQRLR--- 69
Cdd:PRK06190   19 LNRPEARNALSAALRRALFAALAEADADDDVDVVVL-TGADPAFCAGLDLKElggdgsayGAQDALPNPSPAWPAMRkpv 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 -------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVN 112
Cdd:PRK06190   98 igaingaavtgglelalacdiliaserarfadtharvGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAADALRAGLVT 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462510937 113 HAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEgMCYAQNIPTRDRLEGMAAFRE 187
Cdd:PRK06190  178 EVVPHDE----LLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALE-AEAARAHNRSVSPDGIAARRE 247
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 1-195 5.91e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 86.97  E-value: 5.91e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAE-------VGVFVQRLR- 69
Cdd:PRK07511   18 LSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVL-TGAGGFFCAGGNLNrllENRAKPPSVqaasidgLHDWIRAIRa 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 ------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 107
Cdd:PRK07511   97 fpkpviaavegaaagagfslalacdllvaardakfvmayvkvGLTPDGGGSWFLARALPRQLATELLLEGKPISAERLHA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 108 LGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 187
Cdd:PRK07511  177 LGVVNRLAEPGQALAEALALADQLAA----GSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGIAAFLE 252


                  ....*...
gi 2462510937 188 KRTPKFVG 195
Cdd:PRK07511  253 KRAPDYKR 260
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 2-196 1.68e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 85.91  E-value: 1.68e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVF----------------- 64
Cdd:PRK06127   27 NNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAEAVAayeqaveaaqaaladya 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  65 ---VQRLRG----------LMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 109
Cdd:PRK06127  107 kptIACIRGycigggmgiaLACDIriaaedsrfgipaarlglgygyDGVKNLVDLVGPSAAKDLFYTARRFDAAEALRIG 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 110 LVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDR----GTEVDIASGMAIEGMCYAqnipTRDRLEGMAAF 185
Cdd:PRK06127  187 LVHRVTAADDLETALADYAATIAG----NAPLTLRAAKRAIAEllkdEPERDMAACQALVAACFD----SEDYREGRAAF 258

                         250
                  ....*....|.
gi 2462510937 186 REKRTPKFVGK 196
Cdd:PRK06127  259 MEKRKPVFKGR 269
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
2-194 2.66e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 85.32  E-value: 2.66e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   2 NRPSARNALGNVFVSELLETLAQLREDRQVR-VLLfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMN------- 73
Cdd:PRK07509   19 NRPDKMNALDFAMFEELIATIKRLKKDRGIRaVIL--SGEGGAFCAGLDVKSVASSPGNAVKLLFKRLPGNANlaqrvsl 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  74 --------------------------------------------------DIGGTQRLPRCLGVALAKELIFTGRRLSGT 103
Cdd:PRK07509   97 gwrrlpvpviaalegvcfggglqialgadiriaapdtklsimeakwglvpDMAGTVSLRGLVRKDVARELTYTARVFSAE 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 104 EAHVLGLVNHAVaqneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 183
Cdd:PRK07509  177 EALELGLVTHVS------DDPLAAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARESVEQIRLLLGKNQKIAVK 250

                         250
                  ....*....|.
gi 2462510937 184 AFREKRTPKFV 194
Cdd:PRK07509  251 AQMKKRAPKFL 261
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
1-196 7.69e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 83.89  E-value: 7.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-----EREQMSEAEVGVFVQR-------- 67
Cdd:PRK08252   18 INRPEARNAVNAAVAQGLAAALDELDADPDLSVGIL-TGAGGTFCAGMDLKafargERPSIPGRGFGGLTERpprkplia 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  68 ---------------------------------LRGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHA 114
Cdd:PRK08252   97 avegyalaggfelalacdlivaardakfglpevKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTAERAHELGLVNRL 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 115 VAQNEEGDAayqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPKFV 194
Cdd:PRK08252  177 TEPGQALDA----ALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFTSADAKEGATAFAEKRAPVWT 252


                  ..
gi 2462510937 195 GK 196
Cdd:PRK08252  253 GK 254
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 1-191 9.42e-20

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 83.84  E-value: 9.42e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEreqMSEAEVGVFVQRLRG----LMNDIg 76
Cdd:PRK08139   26 LNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLKE---MRAARGLAYFRALFArcsrVMQAI- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  77 gtQRLPR------------------------------------------CL--GVAL--------AKELIFTGRRLSGTE 104
Cdd:PRK08139  101 --VALPQpviarvhgiataagcqlvascdlavaadtarfavpgvniglfCStpMVALsrnvprkqAMEMLLTGEFIDAAT 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 105 AHVLGLVNHAVAQNEEGDAAyqraRALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAA 184
Cdd:PRK08139  179 AREWGLVNRVVPADALDAAV----ARLAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMMAEDAEEGIDA 254


                  ....*..
gi 2462510937 185 FREKRTP 191
Cdd:PRK08139  255 FLEKRPP 261
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 2-196 1.07e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 83.50  E-value: 1.07e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGV----FVQRLRGLMND--- 74
Cdd:PRK06144   24 NRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAVayerRIDRVLGALEQlrv 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  75 ----------IGG-----------------------------------TQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 109
Cdd:PRK06144  104 ptiaaiagacVGGgaaiaaacdlriatpsarfgfpiartlgnclsmsnLARLVALLGAARVKDMLFTARLLEAEEALAAG 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 110 LVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAqnipTRDRLEGMAAFREKR 189
Cdd:PRK06144  184 LVNEVV----EDAALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDGDDLIRMCYM----SEDFREGVEAFLEKR 255


                  ....*..
gi 2462510937 190 TPKFVGK 196
Cdd:PRK06144  256 PPKWKGR 262
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 1-193 1.51e-19

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 83.41  E-value: 1.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE----REQMSEAEVGVFVQRLR------- 69
Cdd:PLN02664   23 LNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIIL-SGAGDHFCSGIDLKTlnsiSEQSSSGDRGRSGERLRrkikflq 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 --------------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRR 99
Cdd:PLN02664  102 daitaieqcrkpviaaihgacigggvdivtacdirycsedaffsvkevdlAITADLGTLQRLPSIVGYGNAMELALTGRR 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 100 LSGTEAHVLGLVNHAVAQNEEGDaayQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRL 179
Cdd:PLN02664  182 FSGSEAKELGLVSRVFGSKEDLD---EGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNSAMLVSDDLN 258

                         250
                  ....*....|....
gi 2462510937 180 EGMAAFREKRTPKF 193
Cdd:PLN02664  259 EAVSAQIQKRKPVF 272
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
1-195 3.85e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 82.33  E-value: 3.85e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADL-----------KEREQMSEAEVGVFVQRLR 69
Cdd:PRK06142   21 LNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKH-FSYGIDLpamagvfgqlgKDGLARPRTDLRREILRLQ 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 GLMN--------------------------------------------------DIGGTQRLPRCLGVALAKELIFTGRR 99
Cdd:PRK06142  100 AAINavadcrkpviaavqgwcigggvdlisacdmryasadakfsvrevdlgmvaDVGSLQRLPRIIGDGHLRELALTGRD 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 100 LSGTEAHVLGLVNHAVaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRL 179
Cdd:PRK06142  180 IDAAEAEKIGLVNRVY---DDADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAAMLPSKDLT 256

                         250
                  ....*....|....*.
gi 2462510937 180 EGMAAFREKRTPKFVG 195
Cdd:PRK06142  257 EAIAAHMEKRPPEFTG 272
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
1-196 7.97e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 78.86  E-value: 7.97e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNAL-GNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAEVGVFVQRLR------- 69
Cdd:PRK09245   18 MNRPETRNALsDNDAVDALVAACAAINADRSVRAVIL-TGAGTAFSSGGNVKdmrARVGAFGGSPADIRQGYRhgiqrip 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 -------------------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSG 102
Cdd:PRK09245   97 lalynlevpviaavngpaigagcdlACMCDIriasetarfaesfvklglipgdGGAWLLPRIIGMARAAEMAFTGDAIDA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 103 TEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 182
Cdd:PRK09245  177 ATALEWGLVSRVVPA----DQLLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAYQALAHHTADHREAV 252

                         250
                  ....*....|....
gi 2462510937 183 AAFREKRTPKFVGK 196
Cdd:PRK09245  253 DAFLEKRPPVFTGR 266
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 1-196 1.50e-17

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 77.76  E-value: 1.50e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRqVRVLLFRSGVKG-VFCAGADLKEREQ------------------------ 55
Cdd:PRK11423   19 FNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkVWSAGHDIHELPSggrdplsyddplrqilrmiqkfpk 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  56 ----MSEAEV--GVFVQRLR-------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PRK11423   98 pviaMVEGSVwgGAFELIMScdliiaaststfamtpanlGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQRALAVGI 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHaVAQNEEGDAAyqrARALAQEILPQAPIAVRLGKvaidrgTEVDI---ASGMAIEGMCYAQNI-----PTRDRLEGM 182
Cdd:PRK11423  178 LNH-VVEVEELEDF---TLQMAHHISEKAPLAIAVIK------EQLRVlgeAHPMNPDEFERIQGLrravyDSEDYQEGM 247

                         250
                  ....*....|....
gi 2462510937 183 AAFREKRTPKFVGK 196
Cdd:PRK11423  248 NAFLEKRKPVFVGH 261
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
1-196 1.69e-17

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 77.81  E-value: 1.69e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEvGVFVQRLR----------- 69
Cdd:PRK06495   19 LDNPPV-NALSRELRDELIAVFDEISERPDVRVVVL-TGAGKVFCAGADLKGRPDVIKGP-GDLRAHNRrtrecfhaire 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 ------------------GLM--NDI-------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PRK06495   96 cakpviaavngpalgaglGLVasCDIivasenavfglpeidvglaGGGKHAMRLFGHSLTRRMMLTGYRVPAAELYRRGV 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAqneeGDAAYQRARALAQEILPQAPIAVRLGKVAIDrgtevdIASGMAI-EGMCYAQNIP-----TRDRLEGMAA 184
Cdd:PRK06495  176 IEACLP----PEELMPEAMEIAREIASKSPLATRLAKDALN------TIENMSLrDGYRYEQDITaklakTEDAKEAQRA 245

                         250
                  ....*....|..
gi 2462510937 185 FREKRTPKFVGK 196
Cdd:PRK06495  246 FLEKRPPVFKGR 257
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
1-196 1.83e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 77.84  E-value: 1.83e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK------EREQMSE---------------- 58
Cdd:PRK07799   20 MNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKaatkkpPGDSFKDgsydpsridallkgrr 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  59 --------------------------------AEVGVFVQRlRGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 106
Cdd:PRK07799   99 ltkpliaavegpaiaggteilqgtdirvagesAKFGISEAK-WSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEAK 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 107 VLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 186
Cdd:PRK07799  178 EIGLIGHVVPD----GQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEGPRAFA 253

                         250
                  ....*....|
gi 2462510937 187 EKRTPKFVGK 196
Cdd:PRK07799  254 EKRAPNFQGR 263
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
1-196 1.96e-17

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 77.43  E-value: 1.96e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKERE--QMSEAEVGV--F--VQRLR----- 69
Cdd:PRK03580   18 LDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAegEAPDADFGPggFagLTEIFdldkp 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 --------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLV 111
Cdd:PRK03580   97 viaavngyafgggfelalaadfivcadnasfalpeaklGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEEALRWGIV 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 112 NHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP----TRDRLEGMAAFRE 187
Cdd:PRK03580  177 NRVVPQAELMD----RARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRSGVLKHYPsvlhSEDALEGPRAFAE 252


                  ....*....
gi 2462510937 188 KRTPKFVGK 196
Cdd:PRK03580  253 KRDPVWKGR 261
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 1-196 2.55e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 74.74  E-value: 2.55e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSE---------------------- 58
Cdd:PRK06210   21 LNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRG-FCAGADMGELQTIDPsdgrrdtdvrpfvgnrrpdyqt 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  59 ------------------AEVGV-FVQRL-------------------RGLMNDIGGTQRLPRCLGVALAKELIFTGRRL 100
Cdd:PRK06210  100 ryhfltalrkpviaaingACAGIgLTHALmcdvrfaadgakfttafarRGLIAEHGISWILPRLVGHANALDLLLSARTF 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 101 SGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPqAPIAVRLGKVAIDRGTEVDIASGMAIEGMcyAQNIPTRDRLE 180
Cdd:PRK06210  180 YAEEALRLGLVNRVVPPDELMERTLAYAEDLARNVSP-ASMAVIKRQLYEDAFQTLAEATARANREM--HESLQRPDFIE 256

                         250
                  ....*....|....*.
gi 2462510937 181 GMAAFREKRTPKFVGK 196
Cdd:PRK06210  257 GVASFLEKRPPRFPGL 272
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 1-191 4.29e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 71.10  E-value: 4.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK----------------------------- 51
Cdd:PRK09076   18 LNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNlfadgdkavaremarrfgeafealsafrg 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  52 ---------------------------EREQMSEAEVGVfvqrlrGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTE 104
Cdd:PRK09076   97 vsiaaingyamggglecalacdiriaeEQAQMALPEASV------GLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAAT 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 105 AHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAA 184
Cdd:PRK09076  171 ALRIGLVEEVVEKGE----AREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNA 246


                  ....*..
gi 2462510937 185 FREKRTP 191
Cdd:PRK09076  247 FLEKRAP 253
PLN02888 PLN02888
enoyl-CoA hydratase
 1-192 5.82e-15

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 70.94  E-value: 5.82e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVG-------VFVQRLR---- 69
Cdd:PLN02888   25 INRPKALNALTRPMMVELAAAFKRLDEDDSVKVIIL-TGSGRAFCSGVDLTAAEEVFKGDVKdvetdpvAQMERCRkpii 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 GLMN--------------DI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNH 113
Cdd:PLN02888  104 GAINgfaitagfeialacDIlvasrgakfidthakfgifpswGLSQKLSRIIGANRAREVSLTAMPLTAETAERWGLVNH 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 114 AVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIE---GMCYAQNIpTRDRLEGMAAFREKRT 190
Cdd:PLN02888  184 VVEESE----LLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEkerAHDYYNGM-TKEQFQKMQEFIAGRS 258


                  ..
gi 2462510937 191 PK 192
Cdd:PLN02888  259 SK 260
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 1-196 1.49e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 69.57  E-value: 1.49e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQM---SEAEVGVFVQRLRGLMNDI-- 75
Cdd:PRK05995   19 LNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVL-AGAGKAFCAGADLNWMKKMagySDDENRADARRLADMLRAIyr 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  76 ---------------GGT-----------------------------QRLP---RCLGVALAKELIFTGRRLSGTEAHVL 108
Cdd:PRK05995   98 cpkpviarvhgdayaGGMglvaacdiavaadhavfclsevrlglipaTISPyviRAMGERAARRYFLTAERFDAAEALRL 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 109 GLVNHAVAQnEEGDAAYQrarALAQEILPQAPIAVRLGKVAIDrgtevDIAsGMAIEGMCYAQnipTRDRL--------- 179
Cdd:PRK05995  178 GLVHEVVPA-EALDAKVD---ELLAALVANSPQAVRAGKRLVR-----DVA-GRPIDAALIAD---TASRIalirateea 244

                         250
                  ....*....|....*...
gi 2462510937 180 -EGMAAFREKRTPKFVGK 196
Cdd:PRK05995  245 rEGVAAFLEKRKPAWRGR 262
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 1-196 4.50e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 65.71  E-value: 4.50e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKERE-----------QMSEAEVGVFVQRLR 69
Cdd:PRK08140   19 LNRPDKLNSFTREMHRELREALDQV-EDDGARALLLTGAGRG-FCAGQDLADRDvtpggampdlgESIETFYNPLVRRLR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 -------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 106
Cdd:PRK08140   97 alplpviaavngvaagaganlalacdivlaarsasfiqafvkiGLVPDSGGTWFLPRLVGMARALGLALLGEKLSAEQAE 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 107 VLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 186
Cdd:PRK08140  177 QWGLIWRVVDDAALADEAQQLAAHLAT----QPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADYAEGVSAFL 252

                         250
                  ....*....|
gi 2462510937 187 EKRTPKFVGK 196
Cdd:PRK08140  253 EKRAPRFTGR 262
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
1-139 7.28e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 64.92  E-value: 7.28e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK--------------------EREQMS--- 57
Cdd:PRK08259   18 LNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVL-WGAGGTFCAGADLKavgtgrgnrlhpsgdgpmgpSRMRLSkpv 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  58 --------------------------EAEVGVFVQRLRGLMNDiGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLV 111
Cdd:PRK08259   97 iaavsgyavagglelalwcdlrvaeeDAVFGVFCRRWGVPLID-GGTVRLPRLIGHSRAMDLILTGRPVDADEALAIGLA 175

                         170       180       190
                  ....*....|....*....|....*....|
gi 2462510937 112 NHAVAQNEegdaAYQRARALAQEI--LPQA 139
Cdd:PRK08259  176 NRVVPKGQ----ARAAAEELAAELaaFPQT 201
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
8-130 8.19e-13

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 66.07  E-value: 8.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   8 NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK---------EREQMSEAEVGVFVQ------------ 66
Cdd:PRK11154   29 NTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINmlaacktaqEAEALARQGQQLFAEiealpipvvaai 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  67 ---------------RLR-----------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHA 114
Cdd:PRK11154  109 hgaclggglelalacHYRvctddpktvlglpevqlGLLPGSGGTQRLPRLIGVSTALDMILTGKQLRAKQALKLGLVDDV 188

                         170
                  ....*....|....*.
gi 2462510937 115 VAQNEEGDAAYQRARA 130
Cdd:PRK11154  189 VPHSILLEVAVELAKK 204
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 1-196 2.28e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 63.87  E-value: 2.28e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADL---------KEREQMSE------------- 58
Cdd:PRK08260   19 LNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIV-TGAGRAFCAGADLsaggntfdlDAPRTPVEadeedradpsddg 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  59 -------------------------AEVGV--------------------FVQRLRGLMNDIGGTQRLPRCLGVALAKEL 93
Cdd:PRK08260   98 vrdgggrvtlrifdslkpviaavngPAVGVgatmtlamdirlastaarfgFVFGRRGIVPEAASSWFLPRLVGLQTALEW 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  94 IFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEilpQAPIAVRLGKVAIDRGTEVDI-ASGMAIEGMCYAQN 172
Cdd:PRK08260  178 VYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADN---TSPVSVALTRQMMWRMAGADHpMEAHRVDSRAIYSR 254

                         250       260
                  ....*....|....*....|....
gi 2462510937 173 IPTRDRLEGMAAFREKRTPKFVGK 196
Cdd:PRK08260  255 GRSGDGKEGVSSFLEKRPAVFPGK 278
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
1-192 4.37e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 62.73  E-value: 4.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRL------------ 68
Cdd:PRK08150   17 LNRPAKRNALNDGLIAALRAAFARLPEGVRAVVL---HGEGDHFCAGLDLSELRERDAGEGMHHSRRWhrvfdkiqygrv 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  69 --------------------------------------RGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PRK08150   94 pviaalhgavvggglelasaahirvadestyfalpegqRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDAQEGERLGL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMC--YAQNIP-TRDRLegmAAFRE 187
Cdd:PRK08150  174 AQYLVPAGE----ALDKAMELARRIAQNAPLTNFAVLNALPRIADMSADDGLFVESLMaaVAQSAPeAKERL---RAFLE 246


                  ....*
gi 2462510937 188 KRTPK 192
Cdd:PRK08150  247 KKAAK 251
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
69-196 1.94e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 61.13  E-value: 1.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  69 RGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEgdaaYQRARALAQEILPQAPIAVRL--- 145
Cdd:PRK06563  132 RGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQEALRLGLVQEVVPPGEQ----LERAIELAERIARAAPLGVQAtla 207

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462510937 146 -GKVAIDRGTEVDIASGMAIegmcYAQNIPTRDRLEGMAAFREKRTPKFVGK 196
Cdd:PRK06563  208 sARAAVREGEAAAAAQLPPE----LRPLFTSEDAKEGVQAFLERRPARFKGR 255
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
1-195 4.11e-11

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 60.37  E-value: 4.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALgnVFVS--ELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE----REQMSEAEV-------GVFVQR 67
Cdd:PRK08258   32 LNRPERKNPL--TFESyaELRDLFRELVYADDVKAVVLT-GAGGNFCSGGDVHEiigpLTKMDMPELlaftrmtGDLVKA 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  68 LR-------------------------------------------GLMN-DIGGTQRLPRCLGVALAKELIFTGRRLSGT 103
Cdd:PRK08258  109 MRacpqpiiaavdgvcagagailamasdlrlgtpsaktaflftrvGLAGaDMGACALLPRIIGQGRASELLYTGRSMSAE 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 104 EAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRgtEVDIASGMAIEGMCYAQNI--PTRDRLEG 181
Cdd:PRK08258  189 EGERWGFFNRLV----EPEELLAEAQALARRLAAGPTFAHGMTKTMLHQ--EWDMGLEEAIEAEAQAQAIcmQTEDFRRA 262

                         250
                  ....*....|....
gi 2462510937 182 MAAFREKRTPKFVG 195
Cdd:PRK08258  263 YEAFVAKRKPVFEG 276
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
1-193 6.76e-11

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 59.65  E-value: 6.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMS-----------EAEVGVF----- 64
Cdd:PRK07327   27 LNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIR-GEGKAFSAGGDLALVEEMAddfevrarvwrEARDLVYnvinc 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  65 ----VQRLRG----------LMNDIG----------GTQRL------------PRCLGVALAKELIFTGRRLSGTEAHVL 108
Cdd:PRK07327  106 dkpiVSAIHGpavgaglvaaLLADISiaakdariidGHTRLgvaagdhaaivwPLLCGMAKAKYYLLLCEPVSGEEAERI 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 109 GLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAID---RGTEVDIASGMAIEGMCYAqnipTRDRLEGMAAF 185
Cdd:PRK07327  186 GLVSLAVDDDELLPKALEVAERLAA----GSQTAIRWTKYALNnwlRMAGPTFDTSLALEFMGFS----GPDVREGLASL 257


                  ....*...
gi 2462510937 186 REKRTPKF 193
Cdd:PRK07327  258 REKRAPDF 265
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 1-196 1.62e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 58.51  E-value: 1.62e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGAD----LKEREQMSEAEVGVFVQRLR------- 69
Cdd:PRK07659   21 LNRPEALNALDEPMLKELLQALKEV-AESSAHIVVLRGNGRG-FSAGGDikmmLSSNDESKFDGVMNTISEIVvtlytmp 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 ----------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 109
Cdd:PRK07659   99 kltisaihgpaaglglsialtadyviadisaklamnfigiGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSATEALDLG 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 110 LVNhAVAQNEEGDAAYQRARALAQEILpQAPIAVRLGKVAIDRGTEVDIasgMAIEGMCYAQNIPTRDRLEGMAAFREKR 189
Cdd:PRK07659  179 LID-EVIGGDFQTAAKQKISEWLQKPL-KAMIETKQIYCELNRSQLEQV---LQLEKRAQYAMRQTADHKEGIRAFLEKR 253


                  ....*..
gi 2462510937 190 TPKFVGK 196
Cdd:PRK07659  254 LPVFKGE 260
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 1-192 3.58e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 57.66  E-value: 3.58e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKER--------------------------E 54
Cdd:PRK08290   19 LNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKH-FSAGHDLGSGtpgrdrdpgpdqhptlwwdgatkpgvE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  55 QMSEAEVGVFVQ---RLR-----------------GLM-----------ND-----------IGGTQRL--PRCLGVALA 90
Cdd:PRK08290   98 QRYAREWEVYLGmcrRWRdlpkptiaqvqgaciagGLMlawvcdlivasDDaffsdpvvrmgIPGVEYFahPWELGPRKA 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  91 KELIFTGRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVD-----IASGMAIE 165
Cdd:PRK08290  178 KELLFTGDRLTADEAHRLGMVNRVVPRDE----LEAETLELARRIAAMPPFGLRLTKRAVNQTLDAQgfraaLDAVFDLH 253

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2462510937 166 GMCYAQN------IPTRDRLEGMAAFREKRTPK 192
Cdd:PRK08290  254 QLGHAHNaevggdRLGGADARGMADARKAAAAK 286
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
59-196 5.92e-09

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 53.97  E-value: 5.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  59 AEVGVFVQRLR--GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAqeil 136
Cdd:PRK05981  131 ARSAYFLQAFRriGLVPDGGSTWLLPRLVGKARAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELA---- 206

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462510937 137 pQAPiAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP--TRDRLEGMAAFREKRTPKFVGK 196
Cdd:PRK05981  207 -NGP-TVALGLIRKLYWDSPENDFEEQLNLEREAQRIAgkTEDFKEGVGAFLQKRPAQFKGR 266
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 1-192 6.26e-09

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 54.24  E-value: 6.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE--REQMSEAEVGV---------FVQRLR 69
Cdd:PRK09120   23 LNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLT-GAGDAWSAGMDLKEyfRETDAQPEILQerirreaygWWRRLR 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 -------GLMNDI---GGTQRLPRC-LGVAlAKELIF---------------------------------TGRRLSGTEA 105
Cdd:PRK09120  102 wyqkptiAMVNGWcfgGGFSPLVACdLAIA-ADEAQFglseinwgippgggvskamadtvghrdalyyimTGETFTGRKA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 106 HVLGLVNHAV--AQNEEgdaayqRARALAQEILPQAPIAVRLGKVAIDRGTEvdiasgmaiegMCYAQNI---------- 173
Cdd:PRK09120  181 AEMGLVNESVplAQLRA------RTRELAAKLLEKNPVVLRAAKDGFKRVRE-----------LTWDQAEdylyakleqa 243

                         250       260
                  ....*....|....*....|...
gi 2462510937 174 ----PTRDRLEGMAAFREKRTPK 192
Cdd:PRK09120  244 nsldPEGGREEGLKQFLDDKSYK 266
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 8-189 8.30e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 53.50  E-value: 8.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   8 NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDI------------ 75
Cdd:PRK06143   29 NILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISRLRDLCDAVrhfpvpviarip 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  76 -----GGTQ--------------------------------RLPRCLGVALAKELIFTGRRLSGTEAHVLGLVnHAVAQN 118
Cdd:PRK06143  109 gwclgGGLElaaacdlriaahdaqfgmpevrvgipsvihaaLLPRLIGWARTRWLLLTGETIDAAQALAWGLV-DRVVPL 187

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462510937 119 EEGDAAYQRaraLAQEILPQAPIAVRLGKVAI----DRGTEVDIASGMAIEGMCYAQNIPTRDrlegMAAFREKR 189
Cdd:PRK06143  188 AELDAAVER---LAASLAGCGPQALRQQKRLLreweDMPLDVAIDDSVAEFGAAFLTGEPQRH----MAAFLNRK 255
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 1-195 3.79e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 51.70  E-value: 3.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE-REQMSE--------------------- 58
Cdd:PRK06072   15 MSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIV-TGEGRAFCVGADLSEfAPDFAIdlretfypiireirfsdkiyi 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  59 -AEVGV----------------------FV---QRLrGLMNDIGGTQRLPRcLGVALAKELIFTGRRLSGTEAHVLGLVn 112
Cdd:PRK06072   94 sAINGVtagacigialstdfkfasrdvkFVtafQRL-GLASDTGVAYFLLK-LTGQRFYEILVLGGEFTAEEAERWGLL- 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 113 havaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPK 192
Cdd:PRK06072  171 ------KISEDPLSDAEEMANRISNGPFQSYIAAKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFKEGISSFKEKREPK 244


                  ...
gi 2462510937 193 FVG 195
Cdd:PRK06072  245 FKG 247
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 1-193 3.83e-08

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 51.82  E-value: 3.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ---MSEAEVGVF----VQRL-RGLM 72
Cdd:PRK07396   28 INRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYggyVDDDGVPRLnvldLQRLiRTCP 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  73 N---------DIGGTQ----------------------------------RLPRCLGVALAKELIFTGRRLSGTEAHVLG 109
Cdd:PRK07396  108 KpviamvagyAIGGGHvlhlvcdltiaadnaifgqtgpkvgsfdggygasYLARIVGQKKAREIWFLCRQYDAQEALDMG 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 110 LVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDrgTEVDIASGMA-IEG---MCYAQnipTRDRLEGMAAF 185
Cdd:PRK07396  188 LVNTVVPLADLEKETVRWCR----EMLQNSPMALRCLKAALN--ADCDGQAGLQeLAGnatMLFYM---TEEAQEGRNAF 258


                  ....*...
gi 2462510937 186 REKRTPKF 193
Cdd:PRK07396  259 NEKRQPDF 266
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
1-196 9.40e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 50.44  E-value: 9.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-EREQMSE------AEVGVFVQRLRGLmN 73
Cdd:PRK07468   20 LNRPEKHNALSARMIAELTTAARRLAADAAVRVVVL-TGAGKSFCAGGDLGwMRAQMTAdratriEEARRLAMMLKAL-N 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  74 DI--------------GGTQRLPRC--------------------------------LGVALAKELIFTGRRLSGTEAHV 107
Cdd:PRK07468   98 DLpkpligriqgqafgGGVGLISVCdvaiavsgarfgltetrlglipatispyvvarMGEANARRVFMSARLFDAEEAVR 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 108 LGLVNHAVAQnEEGDAAYQRaralaqEILPQ---APIAV-RLGKVAIDRGTEVDIAS-GMAIEGMcyAQNIPTRDRLEGM 182
Cdd:PRK07468  178 LGLLSRVVPA-ERLDAAVEA------EVTPYlscAPGAVaAAKALVRALGAPIDEAViDATIEAL--ADTWETEEAREGI 248

                         250
                  ....*....|....
gi 2462510937 183 AAFREKRTPKFVGK 196
Cdd:PRK07468  249 AAFFDKRAPAWRGG 262
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 68-151 1.18e-07

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 50.22  E-value: 1.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  68 LRGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGK 147
Cdd:PRK05869  138 LAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDEMVAP----DDVYDAAAAWARRFLDGPPHALAAAK 213


                  ....
gi 2462510937 148 VAID 151
Cdd:PRK05869  214 AGIS 217
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 1-196 1.55e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 50.02  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRsGVKGVFCAGADLKEREQMSEaevgvFVQRLRGLMNDI----- 75
Cdd:PRK07854   15 LQRPERRNALNAELCEELREAVRKA-VDESARAIVLT-GQGTVFCAGADLSGDVYADD-----FPDALIEMLHAIdaapv 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  76 ------------GGTQ---------------------------------RLPRCLGVALAKELIFTGRRLSGTEAHVLGL 110
Cdd:PRK07854   88 pviaaingpaigAGLQlamacdlrvvapeayfqfpvakygialdnwtirRLSSLVGGGRARAMLLGAEKLTAEQALATGM 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 111 VNhavaqnEEGDAAyqRARALAQEILPQAPIAVRLGKVAI-DRGTEVDIASG-MAIEGMCYAqnipTRDRLEGMAAFREK 188
Cdd:PRK07854  168 AN------RIGTLA--DAQAWAAEIAGLAPLALQHAKRVLnDDGAIEEAWPAhKELFDKAWA----SQDAIEAQVARIEK 235


                  ....*...
gi 2462510937 189 RTPKFVGK 196
Cdd:PRK07854  236 RPPKFQGA 243
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
 1-193 1.80e-07

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 49.82  E-value: 1.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLF-----RSGVKGVFCAGADLKEREQ---MSEAEVGVF----VQRL 68
Cdd:COG0447    33 INRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLtgngpSKDGGWAFCSGGDQRVRGRggyVYEDGVGRLnileVQRL 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  69 RGLMN--------------------------------------DIG------GTQRLPRCLGVALAKELIFTGRRLSGTE 104
Cdd:COG0447   113 IRFMPkpviamvagwaiggghvlhvvcdltiasenarfgqtgpDVGsfdagyGSAYLARQVGQKKAREIWFLCRQYSAQE 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 105 AHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDRGTEvdiasGMAieG----------MCYAqnip 174
Cdd:COG0447   193 ALEMGLVNKVVPHAELEEEAVEWAR----EILEKSPTAIRMLKAAFNADDD-----GLA--GqqefageatrLAYM---- 257

                         250
                  ....*....|....*....
gi 2462510937 175 TRDRLEGMAAFREKRTPKF 193
Cdd:COG0447   258 TDEAQEGRDAFLEKRKPDF 276
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 2-115 1.88e-07

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 50.16  E-value: 1.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-REQMSEAE------------------- 60
Cdd:pfam16113   7 NRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGaGERA-FCAGGDVRAlYEAAKAGGgeagrdffreeyrlnylia 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  61 ------------------VGVFVQ-RLR---------------GLMNDIGGTQRLPRC---LGVALAkeliFTGRRLSGT 103
Cdd:pfam16113  86 typkpyvalmdgivmgggVGLSVHgSFRvvtertrfampetaiGLFPDVGGSYFLSRLpgeLGLYLA----LTGARLNGA 161

                         170
                  ....*....|..
gi 2462510937 104 EAHVLGLVNHAV 115
Cdd:pfam16113 162 DALAAGLATHYV 173
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 1-152 1.09e-06

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 48.29  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGAD---------LKEREQMS-EAEVGVF-VQR- 67
Cdd:TIGR02441  28 IDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADiqmiaacktAQEVTQLSqEGQEMFErIEKs 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  68 -----------------------------------------LRGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 106
Cdd:TIGR02441 108 qkpivaaisgsclggglelalachyriatkdrktllglpevMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAK 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2462510937 107 VLGLVNHAVAQNEEG-DAAYQRARALAQEILPQAPIAVRLGKVAIDR 152
Cdd:TIGR02441 188 KMGIVDQLVDPLGPGlKPAEENTIEYLEEVAVKFAQGLANGKLSINR 234
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
77-193 1.45e-06

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 47.33  E-value: 1.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  77 GTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVA---IDRG 153
Cdd:PRK08321  184 GSAYLARQVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAR----EINGKSPTAMRMLKYAfnlTDDG 259

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2462510937 154 -TEVDIASGMAIEgMCYAqnipTRDRLEGMAAFREKRTPKF 193
Cdd:PRK08321  260 lVGQQLFAGEATR-LAYM----TDEAQEGRDAFLEKRDPDW 295
PLN02921 PLN02921
naphthoate synthase
 1-193 5.01e-06

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 45.93  E-value: 5.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ-----------MSEAEVGVFVQRL- 68
Cdd:PLN02921   82 INRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKdgyvgpddagrLNVLDLQIQIRRLp 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  69 -------RG----------LMNDIG----------------------GTQRLPRCLGVALAKELIFTGRRLSGTEAHVLG 109
Cdd:PLN02921  162 kpviamvAGyavggghilhMVCDLTiaadnavfgqtgpkvgsfdagyGSSIMARLVGQKKAREMWFLARFYTASEALKMG 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 110 LVNHAV--AQNEEGDAAYQRaralaqEILPQAPIAVRLGKVAIDRGTevDIASGmaIEGMcyAQNIP-----TRDRLEGM 182
Cdd:PLN02921  242 LVNTVVplDELEGETVKWCR------EILRNSPTAIRVLKSALNAAD--DGHAG--LQEL--GGNATllfygSEEGNEGR 309

                         250
                  ....*....|.
gi 2462510937 183 AAFREKRTPKF 193
Cdd:PLN02921  310 TAYLEGRAPDF 320
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
1-71 7.54e-06

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 45.06  E-value: 7.54e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLFRSGvkGVFCAGADLKEREQMSEAEVGVFVQRLRGL 71
Cdd:PRK07827   21 LDSPHNRNALSARLVAQLHDGLRAAAADPAVRaVVLTHTG--GTFCAGADLSEAGGGGGDPYDAAVARAREM 90
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 1-133 1.24e-05

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 44.19  E-value: 1.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLK-----EREQMSEAEVGVFVQRLR------ 69
Cdd:PRK07110   20 MQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILT-GYPNYFATGGTQEgllslQTGKGTFTEANLYSLALNcpipvi 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  70 --------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNH 113
Cdd:PRK07110   99 aamqghaiggglvlGLYADIvvlsresvytanfmkygftpgmGATAILPEKLGLALGQEMLLTARYYRGAELKKRGVPFP 178

                         170       180
                  ....*....|....*....|
gi 2462510937 114 AVAQNEEGDAAYQRARALAQ 133
Cdd:PRK07110  179 VLPRAEVLEKALELARSLAE 198
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
2-124 2.43e-05

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 44.08  E-value: 2.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKERE---QMSEAEV--------GVFVQ---- 66
Cdd:PRK11730   23 DAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSA-KDAFIVGADITEFLslfAAPEEELsqwlhfanSIFNRledl 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  67 -------------------------RLR-------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 108
Cdd:PRK11730  102 pvptvaaingyalgggcecvlatdyRVAspdariglpetklGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKV 181

                         170
                  ....*....|....*.
gi 2462510937 109 GLVNHAVAQNEEGDAA 124
Cdd:PRK11730  182 GAVDAVVAPEKLQEAA 197
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 1-51 3.71e-05

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 43.25  E-value: 3.71e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLK 51
Cdd:PLN02874   26 LNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIK-GAGRAFSAGGDLK 75
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 1-194 8.42e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 42.13  E-value: 8.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGAD-------------------LKEREQMSE--- 58
Cdd:PRK05864   25 LNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG-FSSGADhksagvvphvegltrptyaLRSMELLDDvil 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  59 ---------------------------AEVGVFVQ----RLRGLMN-----DIGGTQRLPRCLGVALAKELIFTGRRLSG 102
Cdd:PRK05864  104 alrrlhqpviaavngpaiggglclalaADIRVASSsayfRAAGINNgltasELGLSYLLPRAIGSSRAFEIMLTGRDVDA 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937 103 TEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTevdIASGMAIEGMcyAQ---NIPTRDRL 179
Cdd:PRK05864  184 EEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSGLDAAS---LEAHMQAEGL--GQlfvRLLTANFE 258

                         250
                  ....*....|....*
gi 2462510937 180 EGMAAFREKRTPKFV 194
Cdd:PRK05864  259 EAVAARAEKRPPVFT 273
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 2-119 1.31e-04

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 41.73  E-value: 1.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   2 NRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-----REQMSEAEVGVFVQ--------- 66
Cdd:PRK05617   19 NRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGaGERG-FCAGGDIRAlyeaaRAGDPLAADRFFREeyrlnalia 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  67 -------------------------RLR---------------GLMNDIGGTQRLPRCLGvALAKELIFTGRRLSGTEAH 106
Cdd:PRK05617   98 rypkpyialmdgivmgggvgisahgSHRivtertkmampetgiGFFPDVGGTYFLSRAPG-ALGTYLALTGARISAADAL 176

                         170
                  ....*....|...
gi 2462510937 107 VLGLVNHAVAQNE 119
Cdd:PRK05617  177 YAGLADHFVPSAD 189
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 1-58 2.08e-04

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 40.95  E-value: 2.08e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSE 58
Cdd:PRK05674   21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLR-GRGRHFSAGADLAWMQQSAD 77
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
3-55 4.89e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 39.67  E-value: 4.89e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462510937   3 RPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQ 55
Cdd:PRK07112   21 RPEAQNTINDRLIAECMDVLDRCEHAATIVVL---EGLPEVFCFGADFSAIAE 70
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
8-150 5.33e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 39.57  E-value: 5.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   8 NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMS--------------------EAEVGVFV-- 65
Cdd:PRK07938   23 NALPSAGWFALADAITAAGADPDTRVVVLRAEGRG-FNAGVDIKELQATPgftalidanrgcfaafravyECAVPVIAav 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937  66 -----------------------------QRLRGLMndiGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVnHAVA 116
Cdd:PRK07938  102 hgfclgggiglvgnadvivasddatfglpEVDRGAL---GAATHLQRLVPQHLMRALFFTAATITAAELHHFGSV-EEVV 177

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2462510937 117 QNEEGDAAyqrARALAQEILPQAPIAVRLGKVAI 150
Cdd:PRK07938  178 PRDQLDEA---ALEVARKIAAKDTRVIRAAKEAL 208
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
1-62 1.44e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 38.48  E-value: 1.44e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKE-REQMSEAEVG 62
Cdd:PRK08272   25 LNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKG-FCAGYDLSAyAEGSSSGGGG 86
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 1-50 4.32e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 37.01  E-value: 4.32e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADL 50
Cdd:PRK05870   18 VNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVV-TGAGKAFCAGADL 66
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 1-83 8.96e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 35.87  E-value: 8.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462510937   1 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIG-GTQ 79
Cdd:PRK07260   17 LNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDEDDVQSLVKIAELVNEISfAIK 95


                  ....
gi 2462510937  80 RLPR 83
Cdd:PRK07260   96 QLPK 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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