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Conserved domains on  [gi|2462513798|ref|XP_054194809|]
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dehydrodolichyl diphosphate synthase complex subunit DHDDS isoform X4 [Homo sapiens]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10087541)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates

CATH:  3.40.1180.10
EC:  2.5.1.-
Gene Ontology:  GO:0004659|GO:0016094
PubMed:  16900467|12636086|12135472
SCOP:  4003318

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 28-214 4.91e-97

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


:

Pssm-ID: 259850  Cd Length: 219  Bit Score: 284.65  E-value: 4.91e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEE 107
Cdd:cd00475     1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 108 kekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYN----------------------------------NDISESL 153
Cdd:cd00475    81 ---LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTgltlnialnyggrdeivravrkiardvkageldpEDITEEL 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462513798 154 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:cd00475   158 ISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
 
Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 28-214 4.91e-97

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 284.65  E-value: 4.91e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEE 107
Cdd:cd00475     1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 108 kekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYN----------------------------------NDISESL 153
Cdd:cd00475    81 ---LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTgltlnialnyggrdeivravrkiardvkageldpEDITEEL 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462513798 154 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:cd00475   158 ISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 32-217 9.85e-90

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 266.15  E-value: 9.85e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  32 IMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFsrLMEEKEKL 111
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEY--LRRELPEL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 112 QKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYN--------------------------------NDISESLLDKCLY 159
Cdd:pfam01255  79 HKNGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTgltlnialnyggrdeivdavrkivkegkkldpEDIDEELISSHLY 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462513798 160 TNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNH 217
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRE 216
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
20-214 3.19e-81

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 245.74  E-value: 3.19e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:COG0020    10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 100 KfsrLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNN-------------------------------- 147
Cdd:COG0020    90 Y---LRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGltlnialnyggrweivdavrkiardvaageld 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462513798 148 --DISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:COG0020   167 peDIDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQ 235
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 27-218 2.05e-69

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 214.96  E-value: 2.05e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  27 KHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRlme 106
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDR--- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 107 EKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNN----------------------------------DISES 152
Cdd:TIGR00055  78 EVKELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDftlniafnyggrneilhavkqiaekvksgkllpeDIDEE 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462513798 153 LLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNHS 218
Cdd:TIGR00055 158 TLNKHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHR 223
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 20-214 3.85e-57

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 184.31  E-value: 3.85e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14830   17 LDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 100 KFSRLMEEkekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATK-----------NYN---------------------- 146
Cdd:PRK14830   97 FLDKFVPE---LIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKnntglilnfalNYGgraeivsavkeiakdvldgkln 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462513798 147 -NDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:PRK14830  174 pEDITEELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQ 242
 
Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 28-214 4.91e-97

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 284.65  E-value: 4.91e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEE 107
Cdd:cd00475     1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 108 kekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYN----------------------------------NDISESL 153
Cdd:cd00475    81 ---LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTgltlnialnyggrdeivravrkiardvkageldpEDITEEL 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462513798 154 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:cd00475   158 ISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 32-217 9.85e-90

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 266.15  E-value: 9.85e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  32 IMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFsrLMEEKEKL 111
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEY--LRRELPEL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 112 QKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYN--------------------------------NDISESLLDKCLY 159
Cdd:pfam01255  79 HKNGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTgltlnialnyggrdeivdavrkivkegkkldpEDIDEELISSHLY 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462513798 160 TNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNH 217
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRE 216
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
20-214 3.19e-81

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 245.74  E-value: 3.19e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:COG0020    10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 100 KfsrLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNN-------------------------------- 147
Cdd:COG0020    90 Y---LRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGltlnialnyggrweivdavrkiardvaageld 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462513798 148 --DISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:COG0020   167 peDIDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQ 235
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 27-218 2.05e-69

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 214.96  E-value: 2.05e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  27 KHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRlme 106
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDR--- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 107 EKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNN----------------------------------DISES 152
Cdd:TIGR00055  78 EVKELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDftlniafnyggrneilhavkqiaekvksgkllpeDIDEE 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462513798 153 LLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNHS 218
Cdd:TIGR00055 158 TLNKHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHR 223
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 20-214 3.85e-57

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 184.31  E-value: 3.85e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14830   17 LDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 100 KFSRLMEEkekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATK-----------NYN---------------------- 146
Cdd:PRK14830   97 FLDKFVPE---LIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKnntglilnfalNYGgraeivsavkeiakdvldgkln 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462513798 147 -NDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:PRK14830  174 pEDITEELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQ 242
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 25-214 3.33e-54

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 176.68  E-value: 3.33e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLarqkFSR- 103
Cdd:PRK14831   20 LPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTL----FERv 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 104 LMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNN----------------------------------DI 149
Cdd:PRK14831   96 LRRELEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGihfnvctnyggrqeivqaaraiaqqvqqgeldpsEI 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462513798 150 SESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:PRK14831  176 DENLFESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQ 240
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 19-239 7.74e-47

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 157.92  E-value: 7.74e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  19 IIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAR 98
Cdd:PRK14836    8 IPANENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  99 QKfsrLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATK-----------NYN--------------------- 146
Cdd:PRK14836   88 KA---LDREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTAsntrlilslavSYGgrwdivtaaralarevaagkl 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 147 --NDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYtfwnlfeailqfqmNHSVLQKAR 224
Cdd:PRK14836  165 apDEIDEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDF--------------DAQELQQAL 230

                         250       260
                  ....*....|....*....|
gi 2462513798 225 DMYAEERKR-----QQLERD 239
Cdd:PRK14836  231 EDYASRERRfgktsAQIADR 250
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 24-214 8.42e-47

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 157.70  E-value: 8.42e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  24 PMPKHIAFIMDGNRRYAKK----CQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDL--- 96
Cdd:PRK14840   17 SLPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLfns 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  97 -ARQKFSRLMEEKeklqkhgVCIRVLGDLHLLPLDLQELIAQAVQATKNYN----------------------------- 146
Cdd:PRK14840   97 qLDSQLPYLHENE-------IRLRCIGDLSKLPQELQNNIEQASSATAHYSrmelvlainyggkdelvrafkklhqdlan 169

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462513798 147 -----NDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:PRK14840  170 kkissDDISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQ 242
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 25-215 1.58e-45

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 154.39  E-value: 1.58e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLarqkFSRL 104
Cdd:PRK14832   18 IPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLL----FERL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 105 M-EEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKN-------------YNNDIS-------------------- 150
Cdd:PRK14832   94 LrRELAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNnqaihftvavnygSRNEITracrqvaelvqqgklsadav 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462513798 151 -ESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQM 215
Cdd:PRK14832  174 nEQLVEQHLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQK 239
PRK14834 PRK14834
isoprenyl transferase;
26-213 1.22e-44

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 151.83  E-value: 1.22e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  26 PKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLM 105
Cdd:PRK14834   15 PRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLRLFIRRDL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 106 EEkekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATK-----------NYNN-----------------------DISE 151
Cdd:PRK14834   95 AE---LHRNGVRVRVIGERAGLEADICALLNEAEELTRnntglnlviafNYGSrdeiaravrrlarevaegrldpaSIDA 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462513798 152 SLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 213
Cdd:PRK14834  172 ETISANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEY 233
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
25-213 3.05e-44

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 150.35  E-value: 3.05e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQkfsRL 104
Cdd:PRK14833    4 TLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKK---YL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 105 MEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATK-----------NYNN----------------------DISE 151
Cdd:PRK14833   81 KDERSTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRsfkgftqvlalNYGSkdeisrafkkllesppshigelESLE 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462513798 152 SLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 213
Cdd:PRK14833  161 EEISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDF 222
PRK14835 PRK14835
isoprenyl transferase;
11-214 1.58e-42

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 147.30  E-value: 1.58e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  11 LWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEV 90
Cdd:PRK14835   27 GYEQRLEREVKHGKLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEV 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  91 DGLMDLARQKfSRLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNN----------------DISESLL 154
Cdd:PRK14835  107 ETLMNLFERE-ARRMAVDPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGmllniavgyggreeivDAVKSLL 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 155 DKC----------------------LYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQ 212
Cdd:PRK14835  186 LEAaatgkspeevaaeltpehisahLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRD 265


                  ..
gi 2462513798 213 FQ 214
Cdd:PRK14835  266 YQ 267
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 25-210 2.81e-36

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 129.73  E-value: 2.81e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRl 104
Cdd:PRK14841    3 IPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDR- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 105 meEKEKLQKHGVCIRVLGDLHLLP----------------------------------LDLQELIAQAVQATKNYnnDIS 150
Cdd:PRK14841   82 --EMELLRRERVRVRILGRKEGLPekvlkkwqeveektkefdrmtlviafnyggrreiLDAVESILKDVSQGKKI--ELT 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 151 ESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAI 210
Cdd:PRK14841  158 EETFRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAI 217
PRK14838 PRK14838
isoprenyl transferase;
25-214 5.46e-36

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 129.22  E-value: 5.46e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFsrl 104
Cdd:PRK14838   10 IPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLDSI--- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 105 meEKEKLQKHGVCIRVLGDLHLLPLDLQE----------------------------------LIAQAVQATKNYNNDIS 150
Cdd:PRK14838   87 --EEETFMKNNIRFRIIGDIAKLPEEVQErlneceehtakntgmclvlalsyssrweiteatrQIATLVQNGELNPEEIT 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462513798 151 ESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:PRK14838  165 EESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQ 228
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 11-217 8.85e-35

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 126.40  E-value: 8.85e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  11 LWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVER-QEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSE 89
Cdd:PRK14828   12 VYARRLLGELDGAQVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  90 VDGLMDLarqkfsrLMEEKEKLQKHGVC-IRVLGDLHLLPLDLQELIAQAVQATKNYN---------------------- 146
Cdd:PRK14828   92 LNPLLDI-------IEDVVRQLAPDGRWrVRHVGSLDLLPAPSANRLKEAEEATVGNDgikvnvavgyggrqeivdavrs 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 147 ----------------NDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAI 210
Cdd:PRK14828  165 lltehkdkgtsidelaESVTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRAL 244


                  ....*..
gi 2462513798 211 LQFQMNH 217
Cdd:PRK14828  245 RDYSQRE 251
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 25-214 4.91e-33

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 121.63  E-value: 4.91e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDL-------- 96
Cdd:PRK14842    8 IPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLlvefietr 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  97 ---------------ARQKFSRLMEEK-----EKLQKH-----GVCIRVLGDLHLLPlDLQELIAQAVQATKNYNNDISE 151
Cdd:PRK14842   88 ldtihargirihhsgSRKKLTRTVLDKidfamAKTKKNknltvNFCLNYGSHDELLR-AAQEVFLARKAKKVTLEKPLKE 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462513798 152 SLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:PRK14842  167 KEFEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYE 229
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 23-201 8.03e-32

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 118.00  E-value: 8.03e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  23 GPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARqkfS 102
Cdd:PRK14837    4 NSLPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIA---D 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 103 RLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNN------------------------------DISES 152
Cdd:PRK14837   81 YLSSEFNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGlvlnlainyggrneivravkkflssgldleTLNEN 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2462513798 153 LLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEY 201
Cdd:PRK14837  161 VFSKFLDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEY 209
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 20-213 1.40e-31

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 117.58  E-value: 1.40e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14829    9 IPKNKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRD 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 100 KFSRlmeEKEKLQKHGVCIR-----------VLGDLHllplDLQEL---------------------------IAQAVQA 141
Cdd:PRK14829   89 VIHR---RREQMDEWGVRVRwsgrrprlwksVIDELE----AAEELtknnttmdlvfcvnyggraeiadaaaaIAREVRD 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462513798 142 TKNYNNDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 213
Cdd:PRK14829  162 GKISGDRVTEKMISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEY 233
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 20-209 4.30e-31

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 117.75  E-value: 4.30e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14827   62 IPADRLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRD 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 100 KFSRlmeEKEKLQKHGVCIRVLGDLHLL------PLDLQEL----------------------------IAQAVQATKNY 145
Cdd:PRK14827  142 VVRR---RRDNLNKMGVRIRWVGSRPRLwrsvinELAIAEEmtksndvitinycvnyggrteiteatreIAREAAAGRLN 218

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462513798 146 NNDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEA 209
Cdd:PRK14827  219 PERITESTIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAA 282
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
28-214 1.14e-30

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 115.24  E-value: 1.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARqkfSRLMEE 107
Cdd:PRK14839   12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLR---AYLRNE 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 108 KEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATK-----------NY-------NNDISESLLDKC-------LYTNR 162
Cdd:PRK14839   89 TERLARNGVRLTVIGRRDRLPDGIPEAIARAEAATAggdrlhlriavDYsardailAAAAKALGPEGLsreafsdLLTGD 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2462513798 163 SPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 214
Cdd:PRK14839  169 GGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFH 220
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
33-224 5.76e-27

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 105.07  E-value: 5.76e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  33 MDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLarqkFSRLME-EKEKL 111
Cdd:PRK10240    1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMEL----FVWALDsEVKSL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 112 QKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYN----------------------------------NDISESLLDKC 157
Cdd:PRK10240   77 HRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTgltlniaanyggrwdivqgvrqlaeqvqqgnlqpDQIDEEMLNQH 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462513798 158 LYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTfWNLFEAILqfqmnHSVLQKAR 224
Cdd:PRK10240  157 ICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFD-EQDFEGAL-----NAFANRER 217
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 9-215 2.61e-18

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 83.51  E-value: 2.61e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798   9 LSLWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKS 88
Cdd:PTZ00349    3 LNIIERFITSLLRDFINIKHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798  89 EVD-----GLMDLARQKFSRLMEEKEKLQkhgvcIRVLGDLHLLPLDLQELIAQAVQATKNYNN---------------- 147
Cdd:PTZ00349   83 EIHflfylNLLILINEDFFFKFIKDNKIK-----IKIIGNLSYINDAYRKIIHDIEEKTENFDNillniffsytsrnems 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462513798 148 ----------DISESLL---------------------------DKCLYTNRS--------------------------- 163
Cdd:PTZ00349  158 lckfnpnlyfDTYKNLLeekkilcgsniltdpikegtfaipddeDECDYLDHEleneridldlkfdgdcicgeksflnee 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462513798 164 ----------------PHPDILIRTSGEVRLSDFLLWQTSH-SCLVFQPVLWPEYTFWNLFEAILQFQM 215
Cdd:PTZ00349  238 qieivnyhkklltsdlPPPNILIRTSGEKRLSDFMLYQISEfTEIYFINEYWPIFNFLQFIYIILHYTI 306
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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