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Conserved domains on  [gi|2462589158|ref|XP_054202184|]
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golgin subfamily A member 4 isoform X7 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1467-2162 3.25e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 3.25e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1467 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1546
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1547 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1623
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1624 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1703
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1704 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1768
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1769 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1822
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1823 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1892
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1893 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 1972
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1973 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2052
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2053 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK---YQQKLEQEEnpgndnVTIMEL 2129
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKlaqLELRLEGLE------VRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 2462589158 2130 QTQLAQK--------TTLISDSKLKEQEFREQIHNLEDRLK 2162
Cdd:TIGR02168  942 QERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 762-1686 3.46e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 3.46e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  762 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 837
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  838 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 917
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  918 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 997
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  998 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1077
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1078 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1157
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1158 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1233
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1234 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1313
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1314 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1393
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1394 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1469
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1470 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1549
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1550 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1626
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462589158 1627 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1686
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
PTZ00121 super family cl31754
MAEBL; Provisional
 336-1018 2.80e-13

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.95  E-value: 2.80e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  336 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 415
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  416 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 493
Cdd:PTZ00121  1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  494 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 570
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  571 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 646
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  647 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 724
Cdd:PTZ00121  1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  725 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 804
Cdd:PTZ00121  1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  805 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 883
Cdd:PTZ00121  1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  884 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 963
Cdd:PTZ00121  1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158  964 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1018
Cdd:PTZ00121  1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2193-2236 5.54e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.54e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 2462589158  2193 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2236
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 157-473 1.36e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  157 KEQLIQRLRRMERSLSSYRGKYSElvtAYQMLqREKKKLQGILSQSQDKSLRRIAELREELQMDQQ---AKKHLQEEFDA 233
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSD---ASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  234 SLEEKDQYISVLQTQVSLLKQRLRNGPMNV------DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDgtSVKTLETLQQ 307
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK--EIQELQEQRI 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  308 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmvi 387
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS--- 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  388 aetkrQMHETLEMKEEEIAQLRSRIKQMTTQGEE------LREQKEKSERA----------AFEELEKALSTAQKTEEAR 451
Cdd:TIGR02169  921 -----ELKAKLEALEEELSEIEDPKGEDEEIPEEelsledVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|..
gi 2462589158  452 RKLKAEMDEQIKTIEKTSEEER 473
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKKKR 1017
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1467-2162 3.25e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 3.25e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1467 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1546
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1547 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1623
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1624 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1703
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1704 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1768
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1769 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1822
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1823 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1892
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1893 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 1972
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1973 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2052
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2053 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK---YQQKLEQEEnpgndnVTIMEL 2129
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKlaqLELRLEGLE------VRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 2462589158 2130 QTQLAQK--------TTLISDSKLKEQEFREQIHNLEDRLK 2162
Cdd:TIGR02168  942 QERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 762-1686 3.46e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 3.46e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  762 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 837
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  838 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 917
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  918 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 997
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  998 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1077
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1078 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1157
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1158 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1233
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1234 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1313
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1314 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1393
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1394 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1469
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1470 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1549
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1550 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1626
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462589158 1627 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1686
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
PTZ00121 PTZ00121
MAEBL; Provisional
 336-1018 2.80e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.95  E-value: 2.80e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  336 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 415
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  416 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 493
Cdd:PTZ00121  1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  494 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 570
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  571 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 646
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  647 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 724
Cdd:PTZ00121  1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  725 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 804
Cdd:PTZ00121  1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  805 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 883
Cdd:PTZ00121  1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  884 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 963
Cdd:PTZ00121  1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158  964 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1018
Cdd:PTZ00121  1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 300-822 6.09e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 6.09e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  300 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE----------RLQELEKIKDLHMAEKTKLITQL 369
Cdd:COG1196    239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyellaELARLEQDIARLEERRRELEERL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  370 RDAKNLIEQLEQDKGMVIAETKRQmHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEE 449
Cdd:COG1196    319 EELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  450 ARRKLK--AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 527
Cdd:COG1196    398 LAAQLEelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  528 FQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 607
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  608 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA 687
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  688 HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 767
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158  768 IQRTEKALKDQinQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 822
Cdd:COG1196    718 EEELEEEALEE--QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 308-993 2.01e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.70  E-value: 2.01e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  308 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE-RLQELEKIKDLHMAEKTklitqLRDAKNLIEQLEQDKgMV 386
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLEQQK-QI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  387 IAETKRQMHETLEMKEEEIAQLRSRI-------KQMTTQGEELREQKE------KSERAAFEELEKALSTAQKTEEARRK 453
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLdelaeelAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  454 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkELARKEQELtKKLQTREREFQEQMK 533
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA-ELEELEEEL-EELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  534 VAL----EKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL-------ESSLEKSLQ 602
Cdd:TIGR02168  465 ELReeleEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  603 EN-------KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQ--QYQTEMEK-------- 665
Cdd:TIGR02168  545 GRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDlvKFDPKLRKalsyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  666 ------LREKCEQEKETLLKDKEIIFQAHI-----------EEMNEKTLEK---LDVKQTELESLSSELSEVLKARHKLE 725
Cdd:TIGR02168  625 vlvvddLDNALELAKKLRPGYRIVTLDGDLvrpggvitggsAKTNSSILERrreIEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  726 EELSVLKDQTDKMKQELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK---HLKEHQAHV 800
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDlaRLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  801 ENLEADIKRSEGELQQASAKLDVFQSYQSATHE-----QTKAYEEQLAQLQQKLLDLETERIL--LTKQVAEVEAQKKDV 873
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEeaanlRERLESLERRIAATERRLEDLEEQIeeLSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  874 CTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVyESKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKLS 953
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKLAQLEL----RLEGLEVRID 939

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 2462589158  954 AKEDSihiLNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 993
Cdd:TIGR02168  940 NLQER---LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
PTZ00121 PTZ00121
MAEBL; Provisional
 406-1145 2.21e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.78  E-value: 2.21e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  406 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERiSLQQELSRVKQ 485
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED-AKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  486 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREfqEQMKVALEKSQSEYLKisQEKEQQESLALEELELQK 565
Cdd:PTZ00121  1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE--AARKAEEERKAEEARK--AEDAKKAEAVKKAEEAKK 1237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  566 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvhlEAEKNKHNKEITVMVEKHKTElESLKHQQD 645
Cdd:PTZ00121  1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKADEAKKAEEKKKAD-EAKKKAEE 1313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  646 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 725
Cdd:PTZ00121  1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  726 EELSVLKDQTDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQInqlelllkeRDKHLKEHQAHVENL 803
Cdd:PTZ00121  1394 DEAKKKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEA---------KKKAEEAKKAEEAKK 1464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  804 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV----EAQKKDVCTELDA 879
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeEAKKADEAKKAEE 1544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  880 HKiQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 959
Cdd:PTZ00121  1545 KK-KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  960 HILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDA 1038
Cdd:PTZ00121  1624 ELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1039 VSRLETNQKEQIESLTEVHRRElnDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1118
Cdd:PTZ00121  1704 AEELKKKEAEEKKKAEELKKAE--EENKIKAEEAKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780

                          730       740
                   ....*....|....*....|....*..
gi 2462589158 1119 KEEGVKQDTTLNELQEQLKQKSAHVNS 1145
Cdd:PTZ00121  1781 IEEELDEEDEKRRMEVDKKIKDIFDNF 1807
PTZ00121 PTZ00121
MAEBL; Provisional
 1411-1897 5.77e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.63  E-value: 5.77e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1411 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQiQLEL 1490
Cdd:PTZ00121  1286 AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1491 KSKEAYEKDEQINLLKEELD---QQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARimeledhitqktieiESLNE 1567
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK---------------KKAEE 1429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1568 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQvysMKAELETKKKELEHVNLSVKSKEEELKALE 1647
Cdd:PTZ00121  1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK---KKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1648 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL 1727
Cdd:PTZ00121  1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1728 --IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1804
Cdd:PTZ00121  1587 kkAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1805 EAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDscl 1884
Cdd:PTZ00121  1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDK--- 1743

                          490
                   ....*....|...
gi 2462589158 1885 vRQKEVHRVEMEE 1897
Cdd:PTZ00121  1744 -KKAEEAKKDEEE 1755
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 724-1047 6.34e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 6.34e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  724 LEEELSVLKDQTDKMK--QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 801
Cdd:COG1196    198 LERQLEPLERQAEKAEryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  802 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK 881
Cdd:COG1196    278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  882 IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVekenmILQMREGQKKEIEILTQKLSAKEDSIHI 961
Cdd:COG1196    358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  962 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSR 1041
Cdd:COG1196    433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512


                   ....*.
gi 2462589158 1042 LETNQK 1047
Cdd:COG1196    513 ALLLAG 518
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1482-2107 9.20e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 9.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1482 KELQIQLELKSKEAYEKdeQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1561
Cdd:COG1196    216 RELKEELKELEAELLLL--KLRELEAELEELEAELE----ELEAELEELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1562 IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDN---RVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS 1638
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAEleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1639 KEEELKALEDRLESESAAKLAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKS 1718
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAAEL------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1719 VESSQSETLivprsaknvAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSshfemrcqyqeRL 1798
Cdd:COG1196    444 LEEAAEEEA---------ELEEEEEAL----------LELLAELLEEAALLEAALAELLEELAEAAA-----------RL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1799 IKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENvfDDVQKTLQEKELTCQILEQKIK 1878
Cdd:COG1196    494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ--NIVVEDDEVAAAAIEYLKAAKA 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1879 ELDSCLVRQKEVHRVEMEELTSKYEKLQA--LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1956
Cdd:COG1196    572 GRATFLPLDKIRARAALAAALARGAIGAAvdLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1957 EREKQKLGKEIVRLQ-KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEM 2035
Cdd:COG1196    652 EGEGGSAGGSLTGGSrRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462589158 2036 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEI----LDAREE--EMTAKVRDLQTQLEELQK 2107
Cdd:COG1196    732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAIEEyeELEERYDFLSEQREDLEE 809
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 336-1203 4.09e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 4.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  336 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETkrqmheTLEMKEEEIAQLRSRIKQM 415
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY------LLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  416 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 495
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  496 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS--QSEYLKISQEKEQQESLALEELELQKKAILTESE 573
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  574 NKLRDLQQEAETYRTRILELESSLEKSLQENKnqskdLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ 653
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEE-----ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  654 VLKQQYQTEMEKLREkcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 733
Cdd:pfam02463  480 VKLQEQLELLLSRQK--LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  734 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 813
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  814 LQQASAKLDVFQSYQSATHEQTkayEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 893
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLA---EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  894 QNSEMEQKVKSLTQVYESKL-EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKN 972
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKInEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  973 QEKKMEKVKQKAKEmqetlKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES 1052
Cdd:pfam02463  795 KLKAQEEELRALEE-----ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1053 LTEVHRRELNDVISIWEKKLNQQAEELQEIHE-IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1131
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKElEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462589158 1132 LQEQLKQKSAHVNSLAQDEtklKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1203
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLA---KEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 320-639 8.09e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 60.91  E-value: 8.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  320 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVIAETKRQMH 395
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  396 ETLEMKEEEIAQLRSRIKQMttqgEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKtIEKTSEEERis 475
Cdd:pfam17380  361 ELERIRQEEIAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQ-IRAEQEEAR-- 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  476 lQQELSRVKQEVVDVMKKSSEEQIAK---LQKLHEKELARKEQELTKKLQTRER-EFQEQMKVALEKSQSEYLKISQEKE 551
Cdd:pfam17380  434 -QREVRRLEEERAREMERVRLEEQERqqqVERLRQQEEERKRKKLELEKEKRDRkRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  552 QQESLALEELELQKKAILTESEnklrdlQQEAETYRTRILELESslEKSLQENKNQSKDLAVHLEA-EKNKHNKEITVMV 630
Cdd:pfam17380  513 RKRKLLEKEMEERQKAIYEEER------RREAEEERRKQQEMEE--RRRIQEQMRKATEERSRLEAmEREREMMRQIVES 584


                   ....*....
gi 2462589158  631 EKHKTELES 639
Cdd:pfam17380  585 EKARAEYEA 593
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2193-2236 5.54e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.54e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 2462589158  2193 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2236
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 157-473 1.36e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  157 KEQLIQRLRRMERSLSSYRGKYSElvtAYQMLqREKKKLQGILSQSQDKSLRRIAELREELQMDQQ---AKKHLQEEFDA 233
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSD---ASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  234 SLEEKDQYISVLQTQVSLLKQRLRNGPMNV------DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDgtSVKTLETLQQ 307
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK--EIQELQEQRI 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  308 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmvi 387
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS--- 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  388 aetkrQMHETLEMKEEEIAQLRSRIKQMTTQGEE------LREQKEKSERA----------AFEELEKALSTAQKTEEAR 451
Cdd:TIGR02169  921 -----ELKAKLEALEEELSEIEDPKGEDEEIPEEelsledVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|..
gi 2462589158  452 RKLKAEMDEQIKTIEKTSEEER 473
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKKKR 1017
mukB PRK04863
chromosome partition protein MukB;
158-425 3.20e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 52.65  E-value: 3.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  158 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQS---QDKSL-RRIAELREELQMDQQAKKHLQ----- 228
Cdd:PRK04863   840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllADETLaDRVEEIREQLDEAEEAKRFVQqhgna 919

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  229 ----EEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQlepQAEVFTKEENPESDGEpvvEDGTSvktlET 304
Cdd:PRK04863   920 laqlEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ---RRAHFSYEDAAEMLAK---NSDLN----EK 989

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  305 LQQRVKRQENLLKRCKETIQSHKEQCTL-------LTSEKEALQEQLDERLQELEKI--------KDLHMAEKTKLITQL 369
Cdd:PRK04863   990 LRQRLEQAEQERTRAREQLRQAQAQLAQynqvlasLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELHARL 1069

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462589158  370 RDAKNLIEQLEQdkgmviaetkrqmheTLEMKEEEIAQLRSRIKQMTTQGEELREQ 425
Cdd:PRK04863  1070 SANRSRRNQLEK---------------QLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1357-2173 3.90e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.28  E-value: 3.90e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1357 EKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQ 1436
Cdd:pfam02463  206 AKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1437 DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE--LKSKEAYEKDEQINLLKEELDQQNK 1514
Cdd:pfam02463  286 EELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEelEKELKELEIKREAEEEEEEELEKLQ 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1515 RFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEI----ESLNEVLKNYNQQKDIEHKELVQKLQHF 1590
Cdd:pfam02463  366 EKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELarqlEDLLKEEKKEELEILEEEEESIELKQGK 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1591 QELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIA 1670
Cdd:pfam02463  446 LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRII 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1671 AIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGC 1750
Cdd:pfam02463  526 SAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNL 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1751 VQKTYEE-KISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKY 1829
Cdd:pfam02463  606 AQLDKATlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKA 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1830 SLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT-CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQAL 1908
Cdd:pfam02463  686 ESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADrVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1909 QQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL 1988
Cdd:pfam02463  766 KSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1989 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 2068
Cdd:pfam02463  846 QKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2069 KDDDLKrtaKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQ 2148
Cdd:pfam02463  926 EAEILL---KYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEE 1002

                          810       820
                   ....*....|....*....|....*
gi 2462589158 2149 EFREQIHNLEDRLKKYEKNVYATTV 2173
Cdd:pfam02463 1003 EKKKLIRAIIEETCQRLKEFLELFV 1027
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2194-2233 1.32e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.32e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2462589158 2194 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2233
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
138-425 1.54e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  138 PSDMDSEAEDLVGNSDSLNK-EQLIQRLRRMERSLS---SYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLR-RIAE 212
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERaHEALEDAREQIELLEpirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEaELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  213 LREELQMDQQAKKHLQEEFDASLEEKDQyisvlqtqvsLLKQRLRNGpmnVDVLKPLPQLEPQAEvftkeenpesdgepv 292
Cdd:COG4913    300 LRAELARLEAELERLEARLDALREELDE----------LEAQIRGNG---GDRLEQLEREIERLE--------------- 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  293 vedgtsvKTLETLQQRVKRQENLLKRCKETIQSHKEqctlltsEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDA 372
Cdd:COG4913    352 -------RELEERERRRARLEALLAALGLPLPASAE-------EFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462589158  373 KNLIEQLEQdkgmviaetkrqmhetlemkeeEIAQLRSRIKQMTTQGEELREQ 425
Cdd:COG4913    418 RRELRELEA----------------------EIASLERRKSNIPARLLALRDA 448
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1467-2162 3.25e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 3.25e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1467 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1546
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1547 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1623
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1624 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1703
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1704 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1768
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1769 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1822
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1823 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1892
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1893 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 1972
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1973 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2052
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2053 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK---YQQKLEQEEnpgndnVTIMEL 2129
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKlaqLELRLEGLE------VRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 2462589158 2130 QTQLAQK--------TTLISDSKLKEQEFREQIHNLEDRLK 2162
Cdd:TIGR02168  942 QERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 762-1686 3.46e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 3.46e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  762 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 837
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  838 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 917
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  918 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 997
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  998 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1077
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1078 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1157
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1158 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1233
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1234 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1313
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1314 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1393
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1394 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1469
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1470 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1549
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1550 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1626
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462589158 1627 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1686
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 942-1789 1.47e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.65  E-value: 1.47e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  942 KKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEK------VKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 1015
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKreyegyELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1016 KEKQFNAKMLEMAQANsAGISDAVSRLETNQKEQIESLtEVHRRELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVA 1095
Cdd:TIGR02169  263 LEKRLEEIEQLLEELN-KKIKDLGEEEQLRVKEKIGEL-EAEIASLERSIAEKERELEDAEERLAKL-EAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1096 ELKQKIllfgcekEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1175
Cdd:TIGR02169  340 ELEREI-------EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1176 EQLVELKMLAEEDKRKVSELTSKLKTTDEEfqslkssheksnksLEDKSLEFKKLSEELaiqldiccKKTEALLEAKTNE 1255
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEE--------------KEDKALEIKKQEWKL--------EQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1256 LINISSsKTNAILSRISHCQHRttkvkealliktctVSELEAQLRQLTEEQntlnISFQQAThqlEEKENQIKSMKADIE 1335
Cdd:TIGR02169  471 LYDLKE-EYDRVEKELSKLQRE--------------LAEAEAQARASEERV----RGGRAVE---EVLKASIQGVHGTVA 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1336 SLVTEKE----ALQKEGGNQQQAA-----SEKESCITQLKkelSENINAVTLMKEELKEKKVEISSLSKQ---------L 1397
Cdd:TIGR02169  529 QLGSVGEryatAIEVAAGNRLNNVvveddAVAKEAIELLK---RRKAGRATFLPLNKMRDERRDLSILSEdgvigfavdL 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1398 TDLNVQLQNSIS------------------------------LSEKEAAI---SSLRKQYDEEKCELLDQVQDLSFKVDT 1444
Cdd:TIGR02169  606 VEFDPKYEPAFKyvfgdtlvvedieaarrlmgkyrmvtlegeLFEKSGAMtggSRAPRGGILFSRSEPAELQRLRERLEG 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1445 LSKEKISALEQVDdwsnkfsewkkKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1524
Cdd:TIGR02169  686 LKRELSSLQSELR-----------RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1525 DDKSKM---EKKESNLETELKSQTARIMELEDHITQKTI-EIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNR 1600
Cdd:TIGR02169  755 NVKSELkelEARIEELEEDLHKLEEALNDLEARLSHSRIpEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1601 VKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsesaaKLAELKRKAEQKIAAIKKQLlsqm 1680
Cdd:TIGR02169  835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG-----DLKKERDELEAQLRELERKI---- 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1681 EEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQ------------EEADSQ 1748
Cdd:TIGR02169  906 EELEAQIEK-KRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEiralepvnmlaiQEYEEV 984

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|.
gi 2462589158 1749 GCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE 1789
Cdd:TIGR02169  985 LKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFE 1025
PTZ00121 PTZ00121
MAEBL; Provisional
 336-1018 2.80e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.95  E-value: 2.80e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  336 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 415
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  416 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 493
Cdd:PTZ00121  1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  494 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 570
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  571 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 646
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  647 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 724
Cdd:PTZ00121  1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  725 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 804
Cdd:PTZ00121  1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  805 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 883
Cdd:PTZ00121  1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  884 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 963
Cdd:PTZ00121  1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158  964 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1018
Cdd:PTZ00121  1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1292-2105 1.40e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 1.40e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1292 VSELEAQLRQLtEEQNTLNISFQQATHQLEEKenQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSE 1371
Cdd:TIGR02168  195 LNELERQLKSL-ERQAEKAERYKELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1372 NINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQnsiSLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKIS 1451
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQQKQ---ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1452 ALEQVDDWSNKFSEWKKKAQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELdqqnkrfdclkGEMEDDKSKME 1531
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEEL----ESRLEELEEQLETLRSKVAQLELQIASLNNEI-----------ERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1532 KKESNLETELKSQTARIMELEDHITQKTIEieslnevlknynqQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1611
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAELE-------------ELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1612 ENQVYSMKAELETkkkelehvnlsvkskeeeLKALEDRLESESAAKLAELKrkaEQKIAAIKKQLLSQMEEKEEQYKKGT 1691
Cdd:TIGR02168  481 ERELAQLQARLDS------------------LERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1692 ESHLSE-LNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQR------ 1764
Cdd:TIGR02168  540 EAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkals 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1765 ----------------NLTEKEKLLQRVGQEKEETVSSHF-------EMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEE 1821
Cdd:TIGR02168  620 yllggvlvvddldnalELAKKLRPGYRIVTLDGDLVRPGGvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1822 LEEKNKKYSLIVAQHVEKEggknniQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSK 1901
Cdd:TIGR02168  700 LAELRKELEELEEELEQLR------KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1902 YEKLQALQQMDGRNKPTELLEENTEEKSKSHLvqpkllSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH 1981
Cdd:TIGR02168  774 EEELAEAEAEIEELEAQIEQLKEELKALREAL------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1982 QQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE---- 2057
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKlaql 927

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462589158 2058 ---------ETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEEL 2105
Cdd:TIGR02168  928 elrleglevRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 300-822 6.09e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 6.09e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  300 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE----------RLQELEKIKDLHMAEKTKLITQL 369
Cdd:COG1196    239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyellaELARLEQDIARLEERRRELEERL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  370 RDAKNLIEQLEQDKGMVIAETKRQmHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEE 449
Cdd:COG1196    319 EELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  450 ARRKLK--AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 527
Cdd:COG1196    398 LAAQLEelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  528 FQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 607
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  608 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA 687
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  688 HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 767
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158  768 IQRTEKALKDQinQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 822
Cdd:COG1196    718 EEELEEEALEE--QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 302-586 1.01e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 1.01e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  302 LETLQQRVKRQENLLKRCKETIQSHKEQctllTSEKEALQEQLDERLQELEKikdlhmaEKTKLITQLRDAKNLIEQLEQ 381
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAE----LAELEAELEELRLELEELEL-------ELEEAQAEEYELLAELARLEQ 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  382 DKgMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSEraafEELEKALSTAQKTEEARRKLKAEMDEQ 461
Cdd:COG1196    303 DI-ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE----EELEEAEAELAEAEEALLEAEAELAEA 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  462 IKTIEKTSEEERISLQQELSRVKQ-EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQ 540
Cdd:COG1196    378 EEELEELAEELLEALRAAAELAAQlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 2462589158  541 SEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 586
Cdd:COG1196    458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 568-1337 1.83e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.83e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  568 ILTESENKLRDLQQEAET---YRtRILELESSLEKSLQENKNQSkdlavhLEAEKNKHNKEITVMVEKHKtELESLKHQQ 644
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKaerYK-ELKAELRELELALLVLRLEE------LREELEELQEELKEAEEELE-ELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  645 DALWTEKlqvlkqqyQTEMEKLREKCEQEKETLLKDKEIIfqAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKL 724
Cdd:TIGR02168  266 EEKLEEL--------RLEVSELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  725 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSiikehevsiQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 804
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEEL---------ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  805 ADIKRSEGELQQASakldvfqsyQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKdvctELDAHKIQV 884
Cdd:TIGR02168  407 ARLERLEDRRERLQ---------QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE----ELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  885 QDLMQQLEKQNSEMEQKVKSLtqvyESKLEDGNKEQEQTKQILVEKENM---------ILQMREGQKKEIE--------- 946
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLsgilgvlseLISVDEGYEAAIEaalggrlqa 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  947 ILTQKLSAKEDSIHILNEEYETK-----------FKNQEKKMEKVKQKAKEMQetLKKKLLDQEAKLKKELEN------- 1008
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRvtflpldsikgTEIQGNDREILKNIEGFLG--VAKDLVKFDPKLRKALSYllggvlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1009 -----TALELSQKEK-QFNAKMLEMAQANSAGISdavsrleTNQKEQIESLTEVHRRELNDVisiwEKKLNQQAEELQEI 1082
Cdd:TIGR02168  628 vddldNALELAKKLRpGYRIVTLDGDLVRPGGVI-------TGGSAKTNSSILERRREIEEL----EEKIEELEEKIAEL 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1083 hEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEV 1162
Cdd:TIGR02168  697 -EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1163 DLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEElaiqldicc 1242
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ--------- 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1243 KKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALliktctvSELEAQLRQLTEEQNTLNISFQQATHQLEE 1322
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL-------ALLRSELEELSEELRELESKRSELRRELEE 919

                          810
                   ....*....|....*
gi 2462589158 1323 KENQIKSMKADIESL 1337
Cdd:TIGR02168  920 LREKLAQLELRLEGL 934
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 308-993 2.01e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.70  E-value: 2.01e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  308 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE-RLQELEKIKDLHMAEKTklitqLRDAKNLIEQLEQDKgMV 386
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLEQQK-QI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  387 IAETKRQMHETLEMKEEEIAQLRSRI-------KQMTTQGEELREQKE------KSERAAFEELEKALSTAQKTEEARRK 453
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLdelaeelAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  454 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkELARKEQELtKKLQTREREFQEQMK 533
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA-ELEELEEEL-EELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  534 VAL----EKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL-------ESSLEKSLQ 602
Cdd:TIGR02168  465 ELReeleEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  603 EN-------KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQ--QYQTEMEK-------- 665
Cdd:TIGR02168  545 GRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDlvKFDPKLRKalsyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  666 ------LREKCEQEKETLLKDKEIIFQAHI-----------EEMNEKTLEK---LDVKQTELESLSSELSEVLKARHKLE 725
Cdd:TIGR02168  625 vlvvddLDNALELAKKLRPGYRIVTLDGDLvrpggvitggsAKTNSSILERrreIEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  726 EELSVLKDQTDKMKQELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK---HLKEHQAHV 800
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDlaRLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  801 ENLEADIKRSEGELQQASAKLDVFQSYQSATHE-----QTKAYEEQLAQLQQKLLDLETERIL--LTKQVAEVEAQKKDV 873
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEeaanlRERLESLERRIAATERRLEDLEEQIeeLSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  874 CTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVyESKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKLS 953
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKLAQLEL----RLEGLEVRID 939

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 2462589158  954 AKEDSihiLNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 993
Cdd:TIGR02168  940 NLQER---LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
PTZ00121 PTZ00121
MAEBL; Provisional
 406-1145 2.21e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.78  E-value: 2.21e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  406 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERiSLQQELSRVKQ 485
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED-AKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  486 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREfqEQMKVALEKSQSEYLKisQEKEQQESLALEELELQK 565
Cdd:PTZ00121  1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE--AARKAEEERKAEEARK--AEDAKKAEAVKKAEEAKK 1237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  566 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvhlEAEKNKHNKEITVMVEKHKTElESLKHQQD 645
Cdd:PTZ00121  1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKADEAKKAEEKKKAD-EAKKKAEE 1313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  646 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 725
Cdd:PTZ00121  1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  726 EELSVLKDQTDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQInqlelllkeRDKHLKEHQAHVENL 803
Cdd:PTZ00121  1394 DEAKKKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEA---------KKKAEEAKKAEEAKK 1464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  804 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV----EAQKKDVCTELDA 879
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeEAKKADEAKKAEE 1544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  880 HKiQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 959
Cdd:PTZ00121  1545 KK-KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  960 HILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDA 1038
Cdd:PTZ00121  1624 ELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1039 VSRLETNQKEQIESLTEVHRRElnDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1118
Cdd:PTZ00121  1704 AEELKKKEAEEKKKAEELKKAE--EENKIKAEEAKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780

                          730       740
                   ....*....|....*....|....*..
gi 2462589158 1119 KEEGVKQDTTLNELQEQLKQKSAHVNS 1145
Cdd:PTZ00121  1781 IEEELDEEDEKRRMEVDKKIKDIFDNF 1807
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 339-658 4.30e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.81  E-value: 4.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  339 ALQEQLDERLQELEKIKDLHM-AEKTKLITQLRDAKNLIEQLEqdkgmviaetkrqmhETLEMKEEEIAQLRSRIKQMTT 417
Cdd:COG1196    217 ELKEELKELEAELLLLKLRELeAELEELEAELEELEAELEELE---------------AELAELEAELEELRLELEELEL 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  418 QGEELREQkEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIektsEEERISLQQELSRVKQEVVDVMKK--SS 495
Cdd:COG1196    282 ELEEAQAE-EYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEELEEELEELEEELEEAEEEleEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  496 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENK 575
Cdd:COG1196    357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  576 LRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVL 655
Cdd:COG1196    437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516


                   ...
gi 2462589158  656 KQQ 658
Cdd:COG1196    517 AGL 519
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1070-1865 4.80e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.54  E-value: 4.80e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1070 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQK---------- 1139
Cdd:TIGR02168  203 KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELrlevseleee 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1140 ----SAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEK 1215
Cdd:TIGR02168  283 ieelQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1216 SNKSLEDKSLEFKKLSEE-----------------LAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRT 1278
Cdd:TIGR02168  363 LEAELEELESRLEELEEQletlrskvaqlelqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1279 TKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEK 1358
Cdd:TIGR02168  443 EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1359 ESCITQLKKE----------LSENINAVTLmkEELKEKKVEISSLSKQL--------------TDLNVQLQNSISLSEKE 1414
Cdd:TIGR02168  523 GVLSELISVDegyeaaieaaLGGRLQAVVV--ENLNAAKKAIAFLKQNElgrvtflpldsikgTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1415 AAISSLRKQYDEEKCELLDQVQDLSFKVDTLsKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLElKSKE 1494
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLGGVLVVDDL-DNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILE-RRRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1495 AYEKDEQINLLKEELDQQNKRFDCLKGE---MEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1571
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKEleeLEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1572 YNQQKDIEHKELVQKLQHFQELGEEKdnrvKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE 1651
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEI----EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1652 S--ESAAKLAELKRKAEQKIAAIKKQlLSQMEEKEEQYKKGTESHL---SELNTKLQEREREVHILEEKLKSVES--SQS 1724
Cdd:TIGR02168  835 AteRRLEDLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLnerASLEEALALLRSELEELSEELRELESkrSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1725 ETLIVPRSAKNVAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEmrcQYQERLIKLEHA 1804
Cdd:TIGR02168  914 RRELEELREKLAQLELRLEGL----------EVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE---EARRRLKRLENK 980

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462589158 1805 EAKqhedqsmIGHLQ----EELEEKNKKYSLIVAQHVEKEGGKNNIQ---------AKQNLENVFDDVQKTLQE 1865
Cdd:TIGR02168  981 IKE-------LGPVNlaaiEEYEELKERYDFLTAQKEDLTEAKETLEeaieeidreARERFKDTFDQVNENFQR 1047
PTZ00121 PTZ00121
MAEBL; Provisional
 1411-1897 5.77e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.63  E-value: 5.77e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1411 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQiQLEL 1490
Cdd:PTZ00121  1286 AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1491 KSKEAYEKDEQINLLKEELD---QQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARimeledhitqktieiESLNE 1567
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK---------------KKAEE 1429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1568 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQvysMKAELETKKKELEHVNLSVKSKEEELKALE 1647
Cdd:PTZ00121  1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK---KKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1648 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL 1727
Cdd:PTZ00121  1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1728 --IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1804
Cdd:PTZ00121  1587 kkAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1805 EAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDscl 1884
Cdd:PTZ00121  1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDK--- 1743

                          490
                   ....*....|...
gi 2462589158 1885 vRQKEVHRVEMEE 1897
Cdd:PTZ00121  1744 -KKAEEAKKDEEE 1755
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 724-1047 6.34e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 6.34e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  724 LEEELSVLKDQTDKMK--QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 801
Cdd:COG1196    198 LERQLEPLERQAEKAEryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  802 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK 881
Cdd:COG1196    278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  882 IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVekenmILQMREGQKKEIEILTQKLSAKEDSIHI 961
Cdd:COG1196    358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  962 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSR 1041
Cdd:COG1196    433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512


                   ....*.
gi 2462589158 1042 LETNQK 1047
Cdd:COG1196    513 ALLLAG 518
PTZ00121 PTZ00121
MAEBL; Provisional
 277-804 8.08e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.86  E-value: 8.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  277 EVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKET---IQSHKEQCTLLTSEKEALQEQLDERLQELEK 353
Cdd:PTZ00121  1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkkADAAKKKAEEAKKAAEAAKAEAEAAADEAEA 1361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  354 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmviAETKRQMHETLEMKEEEIAQLRSRIKQmttqGEELREQKEKSERAa 433
Cdd:PTZ00121  1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKK---ADEAKKKAEEDKKKADELKKAAAAKKK----ADEAKKKAEEKKKA- 1433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  434 fEELEKALSTAQKTEEARRKlkAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 513
Cdd:PTZ00121  1434 -DEAKKKAEEAKKADEAKKK--AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK 1510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  514 EQELTKKLQTR----------EREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA 583
Cdd:PTZ00121  1511 KADEAKKAEEAkkadeakkaeEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  584 ETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 663
Cdd:PTZ00121  1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  664 EKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSvLKDQTDKMKQELE 743
Cdd:PTZ00121  1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAK-KEAEEDKKKAEEA 1749

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462589158  744 AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQL-ELLLKERDKHLKEHQAHVENLE 804
Cdd:PTZ00121  1750 KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEdEKRRMEVDKKIKDIFDNFANII 1811
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1025-1910 8.52e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 8.52e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1025 LEMAQANSAGISDAVSRLETN------QKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELK 1098
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlkslerQAEKAERYKELKAELRELELALLVLRLEELREELEELQE-ELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1099 QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1178
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1179 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQldicckktealleakTNELIN 1258
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL---------------NNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1259 ISSSktnaiLSRISHCQHRTTKVKEALLIKTctvseLEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLv 1338
Cdd:TIGR02168  405 LEAR-----LERLEDRRERLQQEIEELLKKL-----EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA- 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1339 teKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEElkekkveisslsKQLTDLNVQLQNSISLSEK-EAAI 1417
Cdd:TIGR02168  474 --EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ------------SGLSGILGVLSELISVDEGyEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1418 SSLrkqydeekceLLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYE 1497
Cdd:TIGR02168  540 EAA----------LGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1498 KDEQINLLKEELDQQNKRFDCLKGEMEDDKSKmekkesnletelkSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKD 1577
Cdd:TIGR02168  610 FDPKLRKALSYLLGGVLVVDDLDNALELAKKL-------------RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1578 IEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESaak 1657
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS--- 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1658 lAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETlivprsaknva 1737
Cdd:TIGR02168  754 -KELTELEAE------IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL----------- 815

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1738 ayteQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH 1817
Cdd:TIGR02168  816 ----NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1818 LQEELEEKNKKyslivaqhvEKEGGKNNIQAKQNLENvfddVQKTLQEKELTCQILEQKIKELdscLVRQKEVHRVEMEE 1897
Cdd:TIGR02168  892 LRSELEELSEE---------LRELESKRSELRRELEE----LREKLAQLELRLEGLEVRIDNL---QERLSEEYSLTLEE 955

                          890
                   ....*....|...
gi 2462589158 1898 LTSKYEKLQALQQ 1910
Cdd:TIGR02168  956 AEALENKIEDDEE 968
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1482-2107 9.20e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 9.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1482 KELQIQLELKSKEAYEKdeQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1561
Cdd:COG1196    216 RELKEELKELEAELLLL--KLRELEAELEELEAELE----ELEAELEELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1562 IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDN---RVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS 1638
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAEleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1639 KEEELKALEDRLESESAAKLAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKS 1718
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAAEL------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1719 VESSQSETLivprsaknvAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSshfemrcqyqeRL 1798
Cdd:COG1196    444 LEEAAEEEA---------ELEEEEEAL----------LELLAELLEEAALLEAALAELLEELAEAAA-----------RL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1799 IKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENvfDDVQKTLQEKELTCQILEQKIK 1878
Cdd:COG1196    494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ--NIVVEDDEVAAAAIEYLKAAKA 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1879 ELDSCLVRQKEVHRVEMEELTSKYEKLQA--LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1956
Cdd:COG1196    572 GRATFLPLDKIRARAALAAALARGAIGAAvdLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1957 EREKQKLGKEIVRLQ-KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEM 2035
Cdd:COG1196    652 EGEGGSAGGSLTGGSrRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462589158 2036 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEI----LDAREE--EMTAKVRDLQTQLEELQK 2107
Cdd:COG1196    732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAIEEyeELEERYDFLSEQREDLEE 809
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 338-954 9.84e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 9.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  338 EALQEQLDERLQELEKikdlhMAEKTklitqlRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTT 417
Cdd:COG1196    192 EDILGELERQLEPLER-----QAEKA------ERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  418 QGEELREQKEKsERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS---EEERISLQQELSRVKQEVVDVmkKS 494
Cdd:COG1196    261 ELAELEAELEE-LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRrelEERLEELEEELAELEEELEEL--EE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  495 SEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEksqseylkisQEKEQQESLALEELELQKKAILTESEN 574
Cdd:COG1196    338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE----------LEELAEELLEALRAAAELAAQLEELEE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  575 KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQV 654
Cdd:COG1196    408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALE-EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  655 LKQQYQTEMEKlrekcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR-HKLEEELSVLKD 733
Cdd:COG1196    487 AEAAARLLLLL-----EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALqNIVVEDDEVAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  734 QTDKMKQELEAKMDEqknhhqQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 813
Cdd:COG1196    562 AIEYLKAAKAGRATF------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  814 LQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 893
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462589158  894 QNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQM--REGQKKEIEILTQKLSA 954
Cdd:COG1196    716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpdLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 389-1008 1.54e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 1.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  389 ETKRQMHETlemkEEEIAQLRSRIKQMTTQGEELREQKEKSERAAfeELEKALSTAQKTEEARRKLKAEMDEQIKTIEKT 468
Cdd:COG1196    176 EAERKLEAT----EENLERLEDILGELERQLEPLERQAEKAERYR--ELKEELKELEAELLLLKLRELEAELEELEAELE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  469 SEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTkklQTREREFQEQMKVALEKSQSEyLKISQ 548
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR---LEQDIARLEERRRELEERLEE-LEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  549 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEitv 628
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL--- 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  629 mvEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEiifQAHIEEMNEKTLEKLDVKQTELE 708
Cdd:COG1196    403 --EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL---EEEEEALLELLAELLEEAALLEA 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  709 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSII---KEHEVSIQ-RTEKALKDQINQLEL 784
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveAAYEAALEaALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  785 LLKERDKHLKEHQAH-VENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV 863
Cdd:COG1196    558 VAAAAIEYLKAAKAGrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  864 AEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK 943
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158  944 EIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLldqeAKLKKELEN 1008
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL----ERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 332-630 1.78e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 1.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  332 LLTSEKEALQEQLDERLQELEKIkDLHMAEKTKLITQLRDAKNLIEQLEQDKGmviaETKRQMHETLEMKEEEIAQLRSR 411
Cdd:COG1196    236 ELEAELEELEAELEELEAELEEL-EAELAELEAELEELRLELEELELELEEAQ----AEEYELLAELARLEQDIARLEER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  412 IKQMTTQGEELREQKEKSERAAfEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM 491
Cdd:COG1196    311 RRELEERLEELEEELAELEEEL-EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  492 KKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEylKISQEKEQQESLALEELELQKKAILTE 571
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE--EEALEEAAEEEAELEEEEEALLELLAE 467

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462589158  572 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMV 630
Cdd:COG1196    468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 309-1101 1.85e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 1.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  309 VKRQENLLKRCKETIQSHKE--------QCTLLTSEKEALQEQLDERLQELEKikdlhmaektkLITQLRDAKNLIEQLE 380
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKElkaelrelELALLVLRLEELREELEELQEELKE-----------AEEELEELTAELQELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  381 QDkgmvIAETKRQMHEtlemKEEEIAQLRSRIKQMTTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEM 458
Cdd:TIGR02168  267 EK----LEELRLEVSE----LEEEIEELQKELYALANEISRLEQQKQilRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  459 DEQIKTIEKTSEEERISLQQELSRVKQEVVDvmkksSEEQIAKLQKLHEKelARKEQELTKKLQTREREFQEQMKVALEK 538
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEE-----LESRLEELEEQLET--LRSKVAQLELQIASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  539 SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLavhleAE 618
Cdd:TIGR02168  412 LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL-----AQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  619 KNKHNKEITVMVEKHKTELESLKHQQDALWTEK--LQVLKQQYQTEmeklrEKCEQEKETLL---------KDKEIIFQA 687
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSgiLGVLSELISVD-----EGYEAAIEAALggrlqavvvENLNAAKKA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  688 hIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQ----------------ELEAKMDEQKN 751
Cdd:TIGR02168  562 -IAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvdDLDNALELAKK 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  752 HHQQ----------------------QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHqahvENLEADIKR 809
Cdd:TIGR02168  641 LRPGyrivtldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL----EELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  810 SEGELQQASAKLdvfqsyqSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQ 889
Cdd:TIGR02168  717 LRKELEELSRQI-------SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  890 QLEKQNSEMEQKVKSLtqvyeSKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETK 969
Cdd:TIGR02168  790 QIEQLKEELKALREAL-----DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  970 FKNQEKKMEKVK--QKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSagisdAVSRLETNQK 1047
Cdd:TIGR02168  865 EELIEELESELEalLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL-----RLEGLEVRID 939

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462589158 1048 EQIESLTEVHRRELndvisiwekklnQQAEELQEIHEIQLQEKEQEVAELKQKI 1101
Cdd:TIGR02168  940 NLQERLSEEYSLTL------------EEAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1574-2135 2.16e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 2.16e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1574 QQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESE 1653
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1654 SAAK--LAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgtESHLSELNTKLQEREREVHILEEKLKSVESSQSETL--IV 1729
Cdd:COG1196    301 EQDIarLEERRRELEERLEELEEELAELEEELEEL-----EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEaeLA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1730 PRSAKNVAAYTEQEEADSQgcvQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQH 1809
Cdd:COG1196    376 EAEEELEELAEELLEALRA---AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1810 EDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKE 1889
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1890 VHRVEMEELTSkyekLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHndlefKLAGAEREKQKLGKEIVR 1969
Cdd:COG1196    533 EAAYEAALEAA----LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR-----AALAAALARGAIGAAVDL 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1970 LQKDLRMLRKEHQQELEILKKEYDQER--EEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEV 2047
Cdd:COG1196    604 VASDLREADARYYVLGDTLLGRTLVAArlEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2048 EAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIM 2127
Cdd:COG1196    684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763


                   ....*...
gi 2462589158 2128 ELQTQLAQ 2135
Cdd:COG1196    764 ELERELER 771
PTZ00121 PTZ00121
MAEBL; Provisional
 337-1064 2.58e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 2.58e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  337 KEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNL--IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 414
Cdd:PTZ00121  1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEErkAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNE 1252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  415 MTTQGEELREQKEKSERAAF--------EELEKAlSTAQKTEEARrklKAEMDEQIKTIEKTSEEERislqqELSRVKQE 486
Cdd:PTZ00121  1253 EIRKFEEARMAHFARRQAAIkaeearkaDELKKA-EEKKKADEAK---KAEEKKKADEAKKKAEEAK-----KADEAKKK 1323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  487 VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKlqtrEREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK 566
Cdd:PTZ00121  1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD----EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  567 AiltESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKdlavhleAEKNKHNKEITVMVEKHKTELESLKHQQDA 646
Cdd:PTZ00121  1400 A---EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK-------AEEAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  647 LWTEKLQVlKQQYQTEMEKLREKCEQEKEtllKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEE 726
Cdd:PTZ00121  1470 KKADEAKK-KAEEAKKADEAKKKAEEAKK---KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK 1545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  727 ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKehQAHVENLEAD 806
Cdd:PTZ00121  1546 KKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK--KAEEAKIKAE 1623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  807 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV--AEVEAQKKDVCTELDAHKIQV 884
Cdd:PTZ00121  1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAkkAEEDEKKAAEALKKEAEEAKK 1703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  885 QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEkenmiLQMREGQKKEIEILTQKLSAKEDSIHI--- 961
Cdd:PTZ00121  1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE-----AKKDEEEKKKIAHLKKEEEKKAEEIRKeke 1778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  962 ------LNEEYETKFKNQEKKMEKVKQKAKEMQE---------TLKKKLLDQEAKLKKELENTALELSQKEKQ--FNAKM 1024
Cdd:PTZ00121  1779 avieeeLDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlviNDSKEMEDSAIKEVADSKNMQLEEADAFEKhkFNKNN 1858

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 2462589158 1025 LEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDV 1064
Cdd:PTZ00121  1859 ENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDI 1898
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 731-1525 4.69e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 4.69e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  731 LKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHE---VSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 807
Cdd:TIGR02168  218 LKAELRELELALLVLRLEELREELEELQEELKEAEeelEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  808 KRSEGELQQASAKLDvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 887
Cdd:TIGR02168  298 SRLEQQKQILRERLA-------NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  888 MQQLEKQNSEMEQKVKSLTQVYEsKLEDGNKEQE----QTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 963
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVAQLEL-QIASLNNEIErleaRLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  964 EEYETKFKNQEKKMEKVKQKAKEMQETLkKKLLDQEAKLKKELENTALELSQKEK-QFNAKMLEMAQANSAGISDAVSRL 1042
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQAL-DAAERELAQLQARLDSLERLQENLEGfSEGVKALLKNQSGLSGILGVLSEL 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1043 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE-------------ELQEIHEIQLQEKEQEVAELKQKILLFGCEKE 1109
Cdd:TIGR02168  529 ISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAflkqnelgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1110 EMNKEIT-----WLkeEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHleklEVDLNKSLKENTFLQEQLVELKML 1184
Cdd:TIGR02168  609 KFDPKLRkalsyLL--GGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPG----GVITGGSAKTNSSILERRREIEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1185 AEEDKR---KVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLdiccKKTEALLEAKTNELINISS 1261
Cdd:TIGR02168  683 EEKIEEleeKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE----AEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1262 SktnailsrishcQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEK 1341
Cdd:TIGR02168  759 L------------EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1342 EALQKEGGNQQQAASEkescITQLKKELSENINAVTLmkeelkekkvEISSLSKQLTDLNVQLQ-NSISLSEKEAAISSL 1420
Cdd:TIGR02168  827 ESLERRIAATERRLED----LEEQIEELSEDIESLAA----------EIEELEELIEELESELEaLLNERASLEEALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1421 RKQYDeekcELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKA---QSRFTQHQNTVKELQIQLELKSKEAYE 1497
Cdd:TIGR02168  893 RSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIdnlQERLSEEYSLTLEEAEALENKIEDDEE 968

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 2462589158 1498 K-DEQINLLK--------------EELDQQNKRFDCLKGEMED 1525
Cdd:TIGR02168  969 EaRRRLKRLEnkikelgpvnlaaiEEYEELKERYDFLTAQKED 1011
PTZ00121 PTZ00121
MAEBL; Provisional
 1412-2123 1.49e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 1.49e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1412 EKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSK-------EKISALEQVDDWSNKFSEWKKKAQ-SRFTQHQNTVKE 1483
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKaeeernnEEIRKFEEARMAHFARRQAAIKAEeARKADELKKAEE 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1484 LQIQLELKSKEAYEKDEQINLLKEE---LDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEdhitqKTI 1560
Cdd:PTZ00121  1289 KKKADEAKKAEEKKKADEAKKKAEEakkADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-----AAE 1363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1561 EIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEkiltlenqvysMKAELETKKKELEhvnlSVKSKE 1640
Cdd:PTZ00121  1364 EKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADE-----------LKKAAAAKKKADE----AKKKAE 1428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1641 EELKALEDRLESESAAKLAELKRKAEQKIAAikkqllsqmeekEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVE 1720
Cdd:PTZ00121  1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKA------------EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK 1496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1721 SSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQrvgQEKEETVSSHFEMRCQYQERlik 1800
Cdd:PTZ00121  1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE---LKKAEELKKAEEKKKAEEAK--- 1570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1801 lehaeaKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVF--DDVQKTLQEKELTCQILEQKIK 1878
Cdd:PTZ00121  1571 ------KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIkaEELKKAEEEKKKVEQLKKKEAE 1644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1879 EldsclVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQpkllsnmeaqhndlEFKLAGAER 1958
Cdd:PTZ00121  1645 E-----KKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK--------------EAEEAKKAE 1705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1959 EKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEydqEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIK 2038
Cdd:PTZ00121  1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE---AEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2039 ETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2118
Cdd:PTZ00121  1783 EELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGE 1862


                   ....*
gi 2462589158 2119 PGNDN 2123
Cdd:PTZ00121  1863 DGNKE 1867
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 761-1508 3.37e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 3.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  761 IKEHEVSIQRTEK---ALKDQINQLELLLKERDKHLKEHQAHVENLEADIKR-SEGELQQASAKLDVFQSYQSATHEQTK 836
Cdd:TIGR02169  232 KEALERQKEAIERqlaSLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIA 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  837 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL------TQVYE 910
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdeLKDYR 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  911 SKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQkAKEMQET 990
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSE----ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ-LAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  991 LKKKLLDQEA---KLKKELENTALELSQKEKQ---------FNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHR 1058
Cdd:TIGR02169  467 YEQELYDLKEeydRVEKELSKLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAG 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1059 RELNDVISIWEKKLNQQAEELQE----------IHEIQLQEKEQEVAELKQKIL----LFGCEKEEMNKEITWLKEEGVK 1124
Cdd:TIGR02169  547 NRLNNVVVEDDAVAKEAIELLKRrkagratflpLNKMRDERRDLSILSEDGVIGfavdLVEFDPKYEPAFKYVFGDTLVV 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1125 QDTT----------LNELQEQLKQKSAHV-------NSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1187
Cdd:TIGR02169  627 EDIEaarrlmgkyrMVTLEGELFEKSGAMtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1188 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELA---IQLDICCKKTEALLEAKTNELINISSSKT 1264
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvkSELKELEARIEELEEDLHKLEEALNDLEA 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1265 NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEAL 1344
Cdd:TIGR02169  787 RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1345 QKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNsisLSEKEAAISSLRKQY 1424
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA---LEEELSEIEDPKGED 943

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1425 DEEKCELLDqVQDLSFKVDTLsKEKISALEQVDdwsNKFSEWKKKAQSRFtqhqNTVKELQIQLELKSKEAYEKDEQINL 1504
Cdd:TIGR02169  944 EEIPEEELS-LEDVQAELQRV-EEEIRALEPVN---MLAIQEYEEVLKRL----DELKEKRAKLEEERKAILERIEEYEK 1014


                   ....
gi 2462589158 1505 LKEE 1508
Cdd:TIGR02169 1015 KKRE 1018
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1465-2104 3.75e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.39  E-value: 3.75e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1465 EWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKgEMEDDKSKMEKKESNLETELKSQ 1544
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE-ELKEEIEELEKELESLEGSKRKL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1545 TARIMELEDHITQKTIEIESLNEVLKNYNQQKdiEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1624
Cdd:PRK03918   258 EEKIRELEERIEELKKEIEELEEKVKELKELK--EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1625 KKKELEHVNLSVKSKEEELKALEDRLES-ESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQ 1703
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEELEERHELyEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIG 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1704 EREREVHILEEKLKSVESSQSETLIVPRSaknvaaYTEQEEADsqgcVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEEt 1783
Cdd:PRK03918   416 ELKKEIKELKKAIEELKKAKGKCPVCGRE------LTEEHRKE----LLEEYTAELKRIEKELKEIEEKERKLRKELRE- 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1784 vsshFEMRCQYQERLIKL-EHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGG----KNNIQAKQNLENVFDD 1858
Cdd:PRK03918   485 ----LEKVLKKESELIKLkELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEikslKKELEKLEELKKKLAE 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1859 VQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLqalqqmdgrnkptelleenteekskshlvqpkl 1938
Cdd:PRK03918   561 LEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL--------------------------------- 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1939 lSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEhqqeLEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 2018
Cdd:PRK03918   608 -KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE----LEELEKKYSEEEYEELREEYLELSRELAGLRAEL 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2019 mrefntqlaqkeqelemtiketinkaqeveaELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE--EEMTAKVR 2096
Cdd:PRK03918   683 -------------------------------EELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALErvEELREKVK 731


                   ....*...
gi 2462589158 2097 DLQTQLEE 2104
Cdd:PRK03918   732 KYKALLKE 739
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 336-1203 4.09e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 4.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  336 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETkrqmheTLEMKEEEIAQLRSRIKQM 415
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY------LLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  416 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 495
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  496 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS--QSEYLKISQEKEQQESLALEELELQKKAILTESE 573
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  574 NKLRDLQQEAETYRTRILELESSLEKSLQENKnqskdLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ 653
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEE-----ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  654 VLKQQYQTEMEKLREkcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 733
Cdd:pfam02463  480 VKLQEQLELLLSRQK--LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  734 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 813
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  814 LQQASAKLDVFQSYQSATHEQTkayEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 893
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLA---EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  894 QNSEMEQKVKSLTQVYESKL-EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKN 972
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKInEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  973 QEKKMEKVKQKAKEmqetlKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES 1052
Cdd:pfam02463  795 KLKAQEEELRALEE-----ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1053 LTEVHRRELNDVISIWEKKLNQQAEELQEIHE-IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1131
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKElEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462589158 1132 LQEQLKQKSAHVNSLAQDEtklKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1203
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLA---KEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1468-1725 7.86e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 7.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1468 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTAR 1547
Cdd:COG1196    249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE----LARLEQDIARLEERRRELEERLEELEEE 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1548 IMELEDHITQKTIEIESLNEVLknynQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK 1627
Cdd:COG1196    325 LAELEEELEELEEELEELEEEL----EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1628 ELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER 1707
Cdd:COG1196    401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                          250
                   ....*....|....*...
gi 2462589158 1708 EVHILEEKLKSVESSQSE 1725
Cdd:COG1196    481 ELLEELAEAAARLLLLLE 498
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 320-639 8.09e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 60.91  E-value: 8.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  320 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVIAETKRQMH 395
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  396 ETLEMKEEEIAQLRSRIKQMttqgEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKtIEKTSEEERis 475
Cdd:pfam17380  361 ELERIRQEEIAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQ-IRAEQEEAR-- 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  476 lQQELSRVKQEVVDVMKKSSEEQIAK---LQKLHEKELARKEQELTKKLQTRER-EFQEQMKVALEKSQSEYLKISQEKE 551
Cdd:pfam17380  434 -QREVRRLEEERAREMERVRLEEQERqqqVERLRQQEEERKRKKLELEKEKRDRkRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  552 QQESLALEELELQKKAILTESEnklrdlQQEAETYRTRILELESslEKSLQENKNQSKDLAVHLEA-EKNKHNKEITVMV 630
Cdd:pfam17380  513 RKRKLLEKEMEERQKAIYEEER------RREAEEERRKQQEMEE--RRRIQEQMRKATEERSRLEAmEREREMMRQIVES 584


                   ....*....
gi 2462589158  631 EKHKTELES 639
Cdd:pfam17380  585 EKARAEYEA 593
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 876-1704 1.06e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 1.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  876 ELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYEsKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAK 955
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLE-RLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  956 EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQAnSAGI 1035
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA-EERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1036 SDAVSRLEtNQKEQIESLTE------VHRRELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQKILLFGCEKE 1109
Cdd:TIGR02169  325 AKLEAEID-KLLAEIEELEReieeerKRRDKLTEEYAELKEELEDLRAELEEV-DKEFAETRDELKDYREKLEKLKREIN 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1110 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLnkslkentflqEQLVELKMLAEEDK 1189
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL-----------EQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1190 RKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAI-- 1267
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLnn 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1268 ----------------------------LSRISHCQHRTTKVKEALLI----------------------KTCTVSELEA 1297
Cdd:TIGR02169  552 vvveddavakeaiellkrrkagratflpLNKMRDERRDLSILSEDGVIgfavdlvefdpkyepafkyvfgDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1298 ------QLRQLTEEQNTL----------NISFQQATHQLEEKEnQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESC 1361
Cdd:TIGR02169  632 arrlmgKYRMVTLEGELFeksgamtggsRAPRGGILFSRSEPA-ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1362 ITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS--------LSEKEAAISSLRKQ----YDEEKC 1429
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSelkelearIEELEEDLHKLEEAlndlEARLSH 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1430 ELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEEL 1509
Cdd:TIGR02169  791 SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE----IQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1510 DQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiehkelvqklqh 1589
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS------------ 934

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1590 fqELGEEKDNRVKEAEEkILTLEnQVYSMKAELETKKKELEHVNlsvkskeeeLKALEDRleSESAAKLAELKRKaEQKI 1669
Cdd:TIGR02169  935 --EIEDPKGEDEEIPEE-ELSLE-DVQAELQRVEEEIRALEPVN---------MLAIQEY--EEVLKRLDELKEK-RAKL 998

                          890       900       910
                   ....*....|....*....|....*....|....*
gi 2462589158 1670 AAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQE 1704
Cdd:TIGR02169  999 EEERKAILERIEEYEKKKREVFMEAFEAINENFNE 1033
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 698-1371 2.04e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 2.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  698 EKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQvdSIIKEHEVSIQRTEKALKD 777
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLER 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  778 QINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI 857
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  858 LLTKQVAEVEAQKKD-------------------VCTELDAHKIQVQDLMQQLEK---QNSEMEQKVKSLTQVYESKLE- 914
Cdd:TIGR02168  397 SLNNEIERLEARLERledrrerlqqeieellkklEEAELKELQAELEELEEELEElqeELERLEEALEELREELEEAEQa 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  915 -DGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKfKNQEKKMEKV------------K 981
Cdd:TIGR02168  477 lDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIEAAlggrlqavvvenL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  982 QKAKEMQETLKKKLLDQEAKL------KKELENTALELSQKEKQFNAKMLEMAQANSAgISDAVS------RLETNQKEQ 1049
Cdd:TIGR02168  556 NAAKKAIAFLKQNELGRVTFLpldsikGTEIQGNDREILKNIEGFLGVAKDLVKFDPK-LRKALSyllggvLVVDDLDNA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1050 IESLTEVHRRE----LNDVISIWEKKLNQQAEElqeiHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEgvkq 1125
Cdd:TIGR02168  635 LELAKKLRPGYrivtLDGDLVRPGGVITGGSAK----TNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE---- 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1126 dttLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEE 1205
Cdd:TIGR02168  707 ---LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1206 FQSLKSSHEKSNKSLEDKSLEFKKLSEELaiqldicckktealleAKTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1285
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAEL----------------TLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1286 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQL 1365
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927


                   ....*.
gi 2462589158 1366 KKELSE 1371
Cdd:TIGR02168  928 ELRLEG 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 672-1209 3.39e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 3.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  672 QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQtelESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKmDEQKN 751
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAEL---EELEAELEELEAELAELEAELEELRLELEELELELEEA-QAEEY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  752 HHQQQVDSIIKEHEVSIQRtEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAT 831
Cdd:COG1196    292 ELLAELARLEQDIARLEER-RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  832 HEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES 911
Cdd:COG1196    371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  912 KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEIltQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKE----- 986
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavav 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  987 ------------------------MQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGI----SDA 1038
Cdd:COG1196    529 ligveaayeaaleaalaaalqnivVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlvaSDL 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1039 VSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1118
Cdd:COG1196    609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1119 KEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSK 1198
Cdd:COG1196    689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                          570
                   ....*....|.
gi 2462589158 1199 LKTTDEEFQSL 1209
Cdd:COG1196    769 LERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 308-701 5.19e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 5.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  308 RVKRQENLLKRCKEtIQSHKEQCTLLTSEKEALQEQLDE---RLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKG 384
Cdd:TIGR02168  665 SAKTNSSILERRRE-IEELEEKIEELEEKIAELEKALAElrkELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  385 MViAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSEraafEELEKALSTAQKTEEARRKLKAEM-DEQIK 463
Cdd:TIGR02168  744 QL-EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE----AQIEQLKEELKALREALDELRAELtLLNEE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  464 TIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkelarkeqeltkKLQTREREFQEQMKVALEKSQSEY 543
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE------------ELEELIEELESELEALLNERASLE 886

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  544 LKISQEKEQQESLALEELELQKKAilTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHN 623
Cdd:TIGR02168  887 EALALLRSELEELSEELRELESKR--SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIE 964

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462589158  624 KEItvmvEKHKTELESLKHQQDALWTEKLQVLkQQYQTEMEKLREKcEQEKETLLKDKEIIFQAhIEEMNEKTLEKLD 701
Cdd:TIGR02168  965 DDE----EEARRRLKRLENKIKELGPVNLAAI-EEYEELKERYDFL-TAQKEDLTEAKETLEEA-IEEIDREARERFK 1035
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2193-2236 5.54e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.54e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 2462589158  2193 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2236
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 389-1147 1.11e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  389 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERaaFEELEKALSTAQKTEEARRKLKAEmdEQIKTIEKt 468
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYELLKEKEALE--RQKEAIER- 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  469 seeERISLQQELSRVKQEVVDVMKKSseEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQmkVALEKSQSEYLKISQ 548
Cdd:TIGR02169  245 ---QLASLEEELEKLTEEISELEKRL--EEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAE--IASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  549 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKeitv 628
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK---- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  629 mVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME---KLREKCEQEKETLLKDKEIifqAHIEEMNEKTLEKLDVKQT 705
Cdd:TIGR02169  394 -LEKLKREINELKRELDRLQEELQRLSEELADLNAAiagIEAKINELEEEKEDKALEI---KKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  706 ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ------QVDSIIKEHEVSIQRTEKALKDQI 779
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASiqgvhgTVAQLGSVGERYATAIEVAAGNRL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  780 NQL----ELLLKERDKHLKEHQA-----------HVENLEADIKRSEGELQQASAKLDVFQSYQSATH------------ 832
Cdd:TIGR02169  550 NNVvvedDAVAKEAIELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKyvfgdtlvvedi 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  833 EQTKAYEEQLAQLQQKLLDLE----------TERILLTKQVAEvEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKv 902
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEksgamtggsrAPRGGILFSRSE-PAELQRLRERLEGLKRELSSLQSELRRIENRLDEL- 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  903 KSLTQVYESKLEDGNKEQEQtkqilvekenmILQMREGQKKEIEILTQKLSAKEDSIhilneeyetkfKNQEKKMEKVKQ 982
Cdd:TIGR02169  708 SQELSDASRKIGEIEKEIEQ-----------LEQEEEKLKERLEELEEDLSSLEQEI-----------ENVKSELKELEA 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  983 KAKEMQETLKKkLLDQEAKLKKELENTALELSQKEKQfnaKMLEMAQANSAGISDAVSRLetNQKEQIESLTEVHRRELN 1062
Cdd:TIGR02169  766 RIEELEEDLHK-LEEALNDLEARLSHSRIPEIQAELS---KLEEEVSRIEARLREIEQKL--NRLTLEKEYLEKEIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1063 DVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAH 1142
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENL-NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918


                   ....*
gi 2462589158 1143 VNSLA 1147
Cdd:TIGR02169  919 LSELK 923
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1943-2161 1.19e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.19e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1943 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRML-----RKEHQQELEILKKEYDQEREEKIKQEQEDLElKHNSTLKQ 2017
Cdd:COG1196    259 EAELAELEAELEELRLELEELELELEEAQAEEYELlaelaRLEQDIARLEERRRELEERLEELEEELAELE-EELEELEE 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2018 LMREFNTQLAQKEQELEMTIKETINKAQEVEA---------ELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE 2088
Cdd:COG1196    338 ELEELEEELEEAEEELEEAEAELAEAEEALLEaeaelaeaeEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE 417

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462589158 2089 EEMTAKVRDLQTQLEELQKKYQQKLEQEEnpgnDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRL 2161
Cdd:COG1196    418 RLEEELEELEEALAELEEEEEEEEEALEE----AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1281-2166 1.92e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.61  E-value: 1.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1281 VKEALLIKTCTVSELEAQLRQLTEEQNTLnISFQQATHQLEEKENQIKSmkADIESLVTEKEALQKEggnqqqaASEKES 1360
Cdd:TIGR02169  182 VEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYELL--KEKEALERQKEAIERQ-------LASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1361 CITQLKKELSENinavtlmKEELKEKKVEISSLSKQLTDLNVQLQNSIS--LSEKEAAISSLRKQYDEEKcellDQVQDL 1438
Cdd:TIGR02169  252 ELEKLTEEISEL-------EKRLEEIEQLLEELNKKIKDLGEEEQLRVKekIGELEAEIASLERSIAEKE----RELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1439 SFKVDTLSKEKISALEQVDDWSNKFSEWKKkaqsRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDC 1518
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERK----RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1519 LKGEMEDdkskMEKKESNLETELKSQTARIMELEdhitqktieieslnevlknyNQQKDIEhkelvQKLQHFQELGEEKD 1598
Cdd:TIGR02169  397 LKREINE----LKRELDRLQEELQRLSEELADLN--------------------AAIAGIE-----AKINELEEEKEDKA 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1599 NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLeseSAAKLAELKRKAEQKIAAIKKQ--- 1675
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA---RASEERVRGGRAVEEVLKASIQgvh 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1676 -LLSQMEEKEEQYKKGTESHLS-ELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSaknvaayteqeeADSQGCVQK 1753
Cdd:TIGR02169  525 gTVAQLGSVGERYATAIEVAAGnRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKM------------RDERRDLSI 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1754 TYEEKISVLQRNLTEKEKLLQRVgqekeetvsshfeMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNkkySLIV 1833
Cdd:TIGR02169  593 LSEDGVIGFAVDLVEFDPKYEPA-------------FKYVFGDTLVVEDIEAARRLMGKYRMVTLEGELFEKS---GAMT 656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1834 AQHVEKEGGKNNiqakqnlenvfddvQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSkyeKLQALQQMDG 1913
Cdd:TIGR02169  657 GGSRAPRGGILF--------------SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ---ELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1914 RNKPTELLEENTEEKSKshlvqpKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKehqqELEILKKEYD 1993
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLK------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE----ALNDLEARLS 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1994 QEREEKIKQEQEDLELKHNSTLKQLmREFNTQLAQKEQELEMTIKETINKAQEVEA--ELLESHQEETNQLLKKIAEKDD 2071
Cdd:TIGR02169  790 HSRIPEIQAELSKLEEEVSRIEARL-REIEQKLNRLTLEKEYLEKEIQELQEQRIDlkEQIKSIEKEIENLNGKKEELEE 868

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2072 DLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKKYQQ-KLEQEENPGNDNVTIMELQTQLAQKTTlISDSKLKEQEF 2150
Cdd:TIGR02169  869 ELEELEAALRD-LESRLGDLKKERDELEAQLRELERKIEElEAQIEKKRKRLSELKAKLEALEEELSE-IEDPKGEDEEI 946

                          890
                   ....*....|....*.
gi 2462589158 2151 REQIHNLEDRLKKYEK 2166
Cdd:TIGR02169  947 PEEELSLEDVQAELQR 962
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
302-539 2.24e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.46  E-value: 2.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  302 LETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQ------------EQLDERLQELEKikDLHMAEKT-----K 364
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeidvASAEREIAELEA--ELERLDASsddlaA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  365 LITQLRDAKNLIEQLEQDKGMVIAETKRqmhetlemKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTA 444
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGR--------LEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD 761

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  445 QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM--KKSSEEQIAKLQKLHEKELARKEQELTKKLQ 522
Cdd:COG4913    762 AVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDadLESLPEYLALLDRLEEDGLPEYEERFKELLN 841

                          250
                   ....*....|....*..
gi 2462589158  523 TREREFQEQMKVALEKS 539
Cdd:COG4913    842 ENSIEFVADLLSKLRRA 858
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 434-1238 4.89e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 4.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  434 FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 513
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  514 EQELTKKLQTREREF----------QEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA 583
Cdd:pfam02463  239 IDLLQELLRDEQEEIesskqeiekeEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  584 ETYRTRILELESSLEKSLQENKNQSKDLavhLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 663
Cdd:pfam02463  319 SEKEKKKAEKELKKEKEEIEELEKELKE---LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  664 EKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELE 743
Cdd:pfam02463  396 ELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  744 AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKrsegelqQASAKLDV 823
Cdd:pfam02463  476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN-------YKVAISTA 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  824 FQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 902
Cdd:pfam02463  549 VIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKlKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  903 KSLTqvYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQ 982
Cdd:pfam02463  629 LKDT--ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  983 KAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQ-FNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRREL 1061
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQkIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1062 NDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCE---KEEMNKEITWLKEEGVKQDTTLNELQEQLKQ 1138
Cdd:pfam02463  787 KVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEeelEELALELKEEQKLEKLAEEELERLEEEITKE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1139 KSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTfLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1218
Cdd:pfam02463  867 ELLQELLLKEEELEEQKLKDELESKEEKEKEEKK-ELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEA 945

                          810       820
                   ....*....|....*....|
gi 2462589158 1219 SLEDKSLEFKKLSEELAIQL 1238
Cdd:pfam02463  946 DEKEKEENNKEEEEERNKRL 965
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1509-2034 6.55e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.05  E-value: 6.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1509 LDQQNKRFDCLKGEMEDDKSK-MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiEHKELVQKL 1587
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEKEEKdLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE-ELETLEAEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1588 QHFQEL-------GEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsESAAKLAE 1660
Cdd:PRK02224   261 EDLRETiaetereREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLE-ECRVAAQA 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1661 LKRKAEQKIAAIKkQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETlivPRSAKNVAAYT 1740
Cdd:PRK02224   340 HNEEAESLREDAD-DLEERAEELREEAAE-LESELEEAREAVEDRREEIEELEEEIEELRERFGDA---PVDLGNAEDFL 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1741 E--QEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQ-----RVGQEKEEtvSSHFEMRCQYQERLIKLEhAEAKQHEDQs 1813
Cdd:PRK02224   415 EelREERDELREREAELEATLRTARERVEEAEALLEagkcpECGQPVEG--SPHVETIEEDRERVEELE-AELEDLEEE- 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1814 mighlQEELEEKNKKYSLIVAQHVEKEGGKNNiqaKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRV 1893
Cdd:PRK02224   491 -----VEEVEERLERAEDLVEAEDRIERLEER---REDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1894 EMEELTSKYEKLQALQQMDGRNKPTELleenteekskshlvqpkllsnmeaQHNDLEFKLAGAErekqKLGKEIVRLQKd 1973
Cdd:PRK02224   563 AEEEAEEAREEVAELNSKLAELKERIE------------------------SLERIRTLLAAIA----DAEDEIERLRE- 613

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462589158 1974 lrmlRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELE 2034
Cdd:PRK02224   614 ----KREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLD 670
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 861-1717 1.24e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.21  E-value: 1.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  861 KQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMilqmreg 940
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD------- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  941 QKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQF 1020
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1021 NAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELN--DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELK 1098
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQleEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1099 QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1178
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1179 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSnksledKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELIN 1258
Cdd:pfam02463  489 LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS------AHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1259 ISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLV 1338
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1339 TEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAIS 1418
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1419 SLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEK 1498
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1499 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELksqtariMELEDHITQKTIEIESLNEVLKNYNQQKDI 1578
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE-------QKLEKLAEEELERLEEEITKEELLQELLLK 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1579 EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1658
Cdd:pfam02463  876 EEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNK 955

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158 1659 AELKRKAEQKIAAIKK------QLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLK 1717
Cdd:pfam02463  956 EEEEERNKRLLLAKEElgkvnlMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 157-473 1.36e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  157 KEQLIQRLRRMERSLSSYRGKYSElvtAYQMLqREKKKLQGILSQSQDKSLRRIAELREELQMDQQ---AKKHLQEEFDA 233
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSD---ASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  234 SLEEKDQYISVLQTQVSLLKQRLRNGPMNV------DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDgtSVKTLETLQQ 307
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK--EIQELQEQRI 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  308 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmvi 387
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS--- 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  388 aetkrQMHETLEMKEEEIAQLRSRIKQMTTQGEE------LREQKEKSERA----------AFEELEKALSTAQKTEEAR 451
Cdd:TIGR02169  921 -----ELKAKLEALEEELSEIEDPKGEDEEIPEEelsledVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|..
gi 2462589158  452 RKLKAEMDEQIKTIEKTSEEER 473
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKKKR 1017
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1531-1875 1.47e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1531 EKKESNLEtELKSQTARIMELEDHITQKTIEIESLNEvlknyNQQKDIEHKELVQKLQHFQelGEEKDNRVKEAEEKILT 1610
Cdd:TIGR02169  170 RKKEKALE-ELEEVEENIERLDLIIDEKRQQLERLRR-----EREKAERYQALLKEKREYE--GYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1611 LENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE---------QKIAAIKKQLLSQME 1681
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGeleaeiaslERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1682 EKEEQYKKGTESHLSELnTKLQEREREVHILEEKLKSVESSQSETLIVPRSAknvaayTEQEEADSQGCVQKT--YEEKI 1759
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEI-EELEREIEEERKRRDKLTEEYAELKEELEDLRAE------LEEVDKEFAETRDELkdYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1760 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRcqyqerlIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK 1839
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLN-------AAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 2462589158 1840 EGGKNNIQAKQN-LENVFDDVQKTLQEKELTCQILEQ 1875
Cdd:TIGR02169  468 EQELYDLKEEYDrVEKELSKLQRELAEAEAQARASEE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1152-1721 1.88e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1152 KLKAHLEKLEVDLnkSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1231
Cdd:COG1196    217 ELKEELKELEAEL--LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1232 EELAiqldicckKTEALLEAKTNELINISSSKTNAILSRISHCQHRttkvkealliktctvSELEAQLRQLTEEQNTLNI 1311
Cdd:COG1196    295 AELA--------RLEQDIARLEERRRELEERLEELEEELAELEEEL---------------EELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1312 SFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEIS 1391
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1392 SLSKQLTDLNVQLQNSIS----LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK 1467
Cdd:COG1196    432 ELEEEEEEEEEALEEAAEeeaeLEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1468 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTAR 1547
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1548 IMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKlqhfQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK 1627
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA----RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1628 ELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER 1707
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                          570
                   ....*....|....
gi 2462589158 1708 EVHILEEKLKSVES 1721
Cdd:COG1196    748 LEEEALEELPEPPD 761
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 210-990 2.16e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 2.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  210 IAELREELQMDQQAKKHLqEEFDASLEEKDQYisvlqTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENpesdg 289
Cdd:TIGR02169  193 IDEKRQQLERLRREREKA-ERYQALLKEKREY-----EGYELLKEKEALERQKEAIERQLASLEEELEKLTEEIS----- 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  290 EPVVEDGTSVKTLETLQQRVKR----QENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKL 365
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  366 ITQLRDAKNLIEQLeQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ 445
Cdd:TIGR02169  342 EREIEEERKRRDKL-TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  446 KTEEARRKLK----------AEMDEQIKTIEKtSEEERISLQQELSRVKQEVVDvmKKSSEEQIAKLQKLHEKELARKEQ 515
Cdd:TIGR02169  421 ELADLNAAIAgieakineleEEKEDKALEIKK-QEWKLEQLAADLSKYEQELYD--LKEEYDRVEKELSKLQRELAEAEA 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  516 ELtKKLQTREREFQEQMKVALEKSQSEYLKISQ---EKEQQESLALEELELQKKAILTESE-------NKLRDLQQEAET 585
Cdd:TIGR02169  498 QA-RASEERVRGGRAVEEVLKASIQGVHGTVAQlgsVGERYATAIEVAAGNRLNNVVVEDDavakeaiELLKRRKAGRAT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  586 Y--RTRILELESSLEKSLqenKNQSKDLAVHLEAEKNKHNKEI------TVMVEkhktELESLKHQQD------------ 645
Cdd:TIGR02169  577 FlpLNKMRDERRDLSILS---EDGVIGFAVDLVEFDPKYEPAFkyvfgdTLVVE----DIEAARRLMGkyrmvtlegelf 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  646 ---------ALWTEKLQVLKQQYQTEMEKLREkceqEKETLLKDKEIIFQ--AHIEEMNEKTLEKLDVKQTELESLSSEL 714
Cdd:TIGR02169  650 eksgamtggSRAPRGGILFSRSEPAELQRLRE----RLEGLKRELSSLQSelRRIENRLDELSQELSDASRKIGEIEKEI 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  715 SEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKnhhqqQVDSIIKEHEVSIQRTEKALKD--------QINQLELLL 786
Cdd:TIGR02169  726 EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELK-----ELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAEL 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  787 KERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV 866
Cdd:TIGR02169  801 SKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  867 EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK--SLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQkKE 944
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKrlSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQ-AE 959

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 2462589158  945 IEILTQKLSAKEDSIHILNEEYET---KFKNQEKKMEKVKQKAKEMQET 990
Cdd:TIGR02169  960 LQRVEEEIRALEPVNMLAIQEYEEvlkRLDELKEKRAKLEEERKAILER 1008
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 191-1030 2.23e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.05  E-value: 2.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  191 EKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNgpmnvdvlkplp 270
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDL------------ 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  271 qlEPQAEVFTKEENPESDGEPVVEdgtsvktlETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQE 350
Cdd:pfam02463  242 --LQELLRDEQEEIESSKQEIEKE--------EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  351 LEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSE 430
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  431 RAAFEELEKALSTAQKTEEARRKLKAEMD-----EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 505
Cdd:pfam02463  392 LKEEELELKSEEEKEAQLLLELARQLEDLlkeekKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  506 HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRD---LQQE 582
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAistAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  583 AETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTE 662
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKD 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  663 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL 742
Cdd:pfam02463  632 TELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  743 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 822
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEE 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  823 VFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 902
Cdd:pfam02463  792 KEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQE 871

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  903 KSLTQVYESKLED-GNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVK 981
Cdd:pfam02463  872 LLLKEEELEEQKLkDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKE 951

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 2462589158  982 QKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQA 1030
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERL 1000
mukB PRK04863
chromosome partition protein MukB;
158-425 3.20e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 52.65  E-value: 3.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  158 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQS---QDKSL-RRIAELREELQMDQQAKKHLQ----- 228
Cdd:PRK04863   840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllADETLaDRVEEIREQLDEAEEAKRFVQqhgna 919

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  229 ----EEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQlepQAEVFTKEENPESDGEpvvEDGTSvktlET 304
Cdd:PRK04863   920 laqlEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ---RRAHFSYEDAAEMLAK---NSDLN----EK 989

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  305 LQQRVKRQENLLKRCKETIQSHKEQCTL-------LTSEKEALQEQLDERLQELEKI--------KDLHMAEKTKLITQL 369
Cdd:PRK04863   990 LRQRLEQAEQERTRAREQLRQAQAQLAQynqvlasLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELHARL 1069

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462589158  370 RDAKNLIEQLEQdkgmviaetkrqmheTLEMKEEEIAQLRSRIKQMTTQGEELREQ 425
Cdd:PRK04863  1070 SANRSRRNQLEK---------------QLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 760-1226 3.40e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.33  E-value: 3.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  760 IIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 839
Cdd:TIGR04523   79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLN 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  840 EQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDA---------HKIQVQDLMQ----QLEKQNSEMEQKVKSLT 906
Cdd:TIGR04523  159 NKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKlelllsnlkKKIQKNKSLEsqisELKKQNNQLKDNIEKKQ 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  907 QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKkEIEILTQKLSAKEDSIHILNEEYE---------------TKFK 971
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQK-ELEQNNKKIKELEKQLNQLKSEISdlnnqkeqdwnkelkSELK 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  972 NQEKKMEKVKQKAKEMQETLKKkLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISdavsrletnQKEQIE 1051
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKIISQ-LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS---------YKQEIK 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1052 SLtEVHRRELNDVISIwEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1131
Cdd:TIGR04523  388 NL-ESQINDLESKIQN-QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRES 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1132 LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1211
Cdd:TIGR04523  466 LETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED 545

                          490
                   ....*....|....*
gi 2462589158 1212 SHEKSNKSLEDKSLE 1226
Cdd:TIGR04523  546 ELNKDDFELKKENLE 560
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1357-2173 3.90e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.28  E-value: 3.90e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1357 EKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQ 1436
Cdd:pfam02463  206 AKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1437 DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE--LKSKEAYEKDEQINLLKEELDQQNK 1514
Cdd:pfam02463  286 EELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEelEKELKELEIKREAEEEEEEELEKLQ 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1515 RFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEI----ESLNEVLKNYNQQKDIEHKELVQKLQHF 1590
Cdd:pfam02463  366 EKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELarqlEDLLKEEKKEELEILEEEEESIELKQGK 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1591 QELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIA 1670
Cdd:pfam02463  446 LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRII 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1671 AIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGC 1750
Cdd:pfam02463  526 SAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNL 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1751 VQKTYEE-KISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKY 1829
Cdd:pfam02463  606 AQLDKATlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKA 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1830 SLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT-CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQAL 1908
Cdd:pfam02463  686 ESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADrVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1909 QQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL 1988
Cdd:pfam02463  766 KSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1989 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 2068
Cdd:pfam02463  846 QKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2069 KDDDLKrtaKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQ 2148
Cdd:pfam02463  926 EAEILL---KYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEE 1002

                          810       820
                   ....*....|....*....|....*
gi 2462589158 2149 EFREQIHNLEDRLKKYEKNVYATTV 2173
Cdd:pfam02463 1003 EKKKLIRAIIEETCQRLKEFLELFV 1027
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1423-2168 4.76e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 4.76e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1423 QYDEEK---CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK----KKAQSRFTQHQNTVKELQIQLELKSKEA 1495
Cdd:TIGR02169  167 EFDRKKekaLEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQallkEKREYEGYELLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1496 YEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESN----LETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1571
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrVKEKIGELEAEIASLERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1572 YNQQ---KDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLS---VKSKEEELKA 1645
Cdd:TIGR02169  327 LEAEidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKlekLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1646 LEDRLESES---AAKLAELKRKAEQKIAAIKkQLLSQMEEKEEQYKKGT-------------ESHLSELNTKLQEREREV 1709
Cdd:TIGR02169  407 ELDRLQEELqrlSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEwkleqlaadlskyEQELYDLKEEYDRVEKEL 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1710 HILEEKLKSVESSQSetLIVPRSAKNVAAyTEQEEADSQGcVQKTYEEKISVLQRNLTEKE----KLLQRVGQEKEETVS 1785
Cdd:TIGR02169  486 SKLQRELAEAEAQAR--ASEERVRGGRAV-EEVLKASIQG-VHGTVAQLGSVGERYATAIEvaagNRLNNVVVEDDAVAK 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1786 SHFEMRCQYQ-ERLIKLEHAEAKQHEDQSMIGHLQE------ELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDD 1858
Cdd:TIGR02169  562 EAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGvigfavDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRM 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1859 VQktlqekeLTCQILEQK--IKELDSCLVRQKEVHRVEMEELTSKYEKLQALQqmdgrnkptelleenteekskshlvqp 1936
Cdd:TIGR02169  642 VT-------LEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLK--------------------------- 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1937 KLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILK------KEYDQEREE----------KI 2000
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEeleedlSSLEQEIENvkselkeleaRI 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2001 KQEQEDL---ELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEEtNQLLKKIAEKDDDLKRTA 2077
Cdd:TIGR02169  768 EELEEDLhklEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK-EYLEKEIQELQEQRIDLK 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2078 KRYEEIlDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGND----NVTIMELQTQLAQKTTLISDSKLKEQEFREQ 2153
Cdd:TIGR02169  847 EQIKSI-EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKErdelEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          810
                   ....*....|....*
gi 2462589158 2154 IHNLEDRLKKYEKNV 2168
Cdd:TIGR02169  926 LEALEEELSEIEDPK 940
PTZ00121 PTZ00121
MAEBL; Provisional
 737-1248 4.81e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 4.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  737 KMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 816
Cdd:PTZ00121  1230 KKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKK 1309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  817 ASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNS 896
Cdd:PTZ00121  1310 KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE----KAEAAEKKKEEAKKKADAAKK 1385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  897 EMEQKVKSlTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 976
Cdd:PTZ00121  1386 KAEEKKKA-DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  977 MEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK-EQIESLTE 1055
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKaDEAKKAEE 1544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1056 VHRRElndviSIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQ 1135
Cdd:PTZ00121  1545 KKKAD-----ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1136 LK----QKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQlveLKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1211
Cdd:PTZ00121  1620 IKaeelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE---EAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696

                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 2462589158 1212 SHEKSNKS--LEDKSLEFKKLSEELAIQLDICCKKTEAL 1248
Cdd:PTZ00121  1697 EAEEAKKAeeLKKKEAEEKKKAEELKKAEEENKIKAEEA 1735
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 889-1721 5.89e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.90  E-value: 5.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  889 QQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET 968
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  969 KfkNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKE 1048
Cdd:pfam02463  249 E--QEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1049 QIESLTEVHRRELndvISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTT 1128
Cdd:pfam02463  327 EKELKKEKEEIEE---LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1129 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1208
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1209 LKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIK 1288
Cdd:pfam02463  484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1289 TCTVSELEAQLRQLTEEQnTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1368
Cdd:pfam02463  564 QKLVRALTELPLGARKLR-LLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1369 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKE 1448
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1449 KISALEQVDDWSNKFSEWKKKAQSRFTQhqntvKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKS 1528
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEE-----EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLK 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1529 KMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1608
Cdd:pfam02463  798 AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEE 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1609 LTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ-----KIAAIKKQLLSQMEEK 1683
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEpeellLEEADEKEKEENNKEE 957

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 2462589158 1684 EEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVES 1721
Cdd:pfam02463  958 EEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDEL 995
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 320-1236 7.89e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.59  E-value: 7.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  320 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLhmaEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 399
Cdd:TIGR00606  151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKAL---ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQIT 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  400 MKEEEIAQLRSRIKQMTTQGEELREQKEKSE--RAAFEELEKALSTAQKTEEARRKLKAEM-----------DEQIKTIE 466
Cdd:TIGR00606  228 SKEAQLESSREIVKSYENELDPLKNRLKEIEhnLSKIMKLDNEIKALKSRKKQMEKDNSELelkmekvfqgtDEQLNDLY 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  467 -------KTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA------KLQKLHEKELARKEQELTKKLQTREREFQEQMK 533
Cdd:TIGR00606  308 hnhqrtvREKERELVDCQRELEKLNKERRLLNQEKTELLVEqgrlqlQADRHQEHIRARDSLIQSLATRLELDGFERGPF 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  534 VALEKSQSEYLKIS-QEKEQQESLALEELELQKKAILTESENKLRDlqqeAETYRTRILELESSLeksLQENKNQSKDLA 612
Cdd:TIGR00606  388 SERQIKNFHTLVIErQEDEAKTAAQLCADLQSKERLKQEQADEIRD----EKKGLGRTIELKKEI---LEKKQEELKFVI 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  613 VHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEM 692
Cdd:TIGR00606  461 KELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  693 NEKTLEKLD----------VKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELeAKMDEQKNHHQQQVDSiIK 762
Cdd:TIGR00606  541 TKDKMDKDEqirkiksrhsDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKEL-ASLEQNKNHINNELES-KE 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  763 EHEVSIQR------TEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK 836
Cdd:TIGR00606  619 EQLSSYEDklfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFIS 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  837 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMeQKVKSLTQVYESKLEDG 916
Cdd:TIGR00606  699 DLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDI-QRLKNDIEEQETLLGTI 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  917 NKEQEQTKQILVEKEnmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEK--KMEKVKQKAKEMQetlkkK 994
Cdd:TIGR00606  778 MPEEESAKVCLTDVT--IMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqhELDTVVSKIELNR-----K 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  995 LLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANsagisdavSRLETNQKEQIESLTEV-HRRELNDVISIWEKKLN 1073
Cdd:TIGR00606  851 LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFE--------EQLVELSTEVQSLIREIkDAKEQDSPLETFLEKDQ 922

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1074 QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQ-DTTLNELQEQLKQKSAHVNSLAQDetk 1152
Cdd:TIGR00606  923 QEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQkETELNTVNAQLEECEKHQEKINED--- 999

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1153 lkahLEKLEVDLNKSLKENTFLQEQLVELKMlaeedKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSE 1232
Cdd:TIGR00606 1000 ----MRLMRQDIDTQKIQERWLQDNLTLRKR-----ENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNH 1070


                   ....
gi 2462589158 1233 ELAI 1236
Cdd:TIGR00606 1071 VLAL 1074
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 457-1167 1.19e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.89  E-value: 1.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  457 EMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIaklqklhekelarkEQELTKKLQTREREFQEQMKVAL 536
Cdd:pfam15921   82 EYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQM--------------ERDAMADIRRRESQSQEDLRNQL 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  537 EKSQSEYLKISQEKEQQESLALEELELQKKAILTEsENKLRDLqqeaetyRTRILELESSLEKSLQENKNQSkdlAVHLE 616
Cdd:pfam15921  148 QNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSH-EGVLQEI-------RSILVDFEEASGKKIYEHDSMS---TMHFR 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  617 AeknkHNKEITVMVEKHKTELESLKHQQDALwTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIifqaHIEEMNEKT 696
Cdd:pfam15921  217 S----LGSAISKILRELDTEISYLKGRIFPV-EDQLEALKSESQNKIELLLQQHQDRIEQLISEHEV----EITGLTEKA 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  697 LEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL-EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEK-- 773
Cdd:pfam15921  288 SSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERdq 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  774 ------ALKDQINQLELLLKERDKHLKEHQAH--------------VENLEADIKRSEGELQQASAKLDVFQSYQSATHE 833
Cdd:pfam15921  368 fsqesgNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQME 447

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  834 QTKAY----EEQLAQLQQKLLDLETERILLTKQVAEVEAQKkdvcTELDAHKIQVQDLMQQLEKQNSEME------QKVK 903
Cdd:pfam15921  448 RQMAAiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKK----MTLESSERTVSDLTASLQEKERAIEatnaeiTKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  904 SLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREgQKKEIEILTQKLsakEDSIHILNEEYETKFKNQEKKMEKVK-- 981
Cdd:pfam15921  524 SRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE-KDKVIEILRQQI---ENMTQLVGQHGRTAGAMQVEKAQLEKei 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  982 -------QKAKEMQETLKKKLLDQEAKLKK-ELENTALELSQKE--------KQFNAKMLEMAQANSAGISDAVSRLET- 1044
Cdd:pfam15921  600 ndrrlelQEFKILKDKKDAKIRELEARVSDlELEKVKLVNAGSErlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVl 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1045 -----NQKEQIESLTEVHRRELNDVISIWEKKLNQ-QAEELQEIHEI--------QLQEKEQEVAELKQKILLFGCEKEE 1110
Cdd:pfam15921  680 krnfrNKSEEMETTTNKLKMQLKSAQSELEQTRNTlKSMEGSDGHAMkvamgmqkQITAKRGQIDALQSKIQFLEEAMTN 759

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462589158 1111 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKS 1167
Cdd:pfam15921  760 ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKA 816
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2194-2233 1.32e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.32e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2462589158 2194 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2233
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1480-1708 1.32e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 50.31  E-value: 1.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1480 TVKELQ----IQLELKSKEayEKDEQINLLKEELDQQNKRFDCLKGEME----DDKSKMEKKESNLETELKSQTARIMEL 1551
Cdd:PRK05771    21 VLEALHelgvVHIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSYLPklnpLREEKKKVSVKSLEELIKDVEEELEKI 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1552 EDHITQKTIEIESLNEVLKNYNQQKDIehkelVQKLQHF----QELGEEKD-----NRVKEAEEKILTLENQVYsmKAEL 1622
Cdd:PRK05771    99 EKEIKELEEEISELENEIKELEQEIER-----LEPWGNFdldlSLLLGFKYvsvfvGTVPEDKLEELKLESDVE--NVEY 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1623 ETKKKELEHVNLSVKSK-----EEELKALE-DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLS 1696
Cdd:PRK05771   172 ISTDKGYVYVVVVVLKElsdevEEELKKLGfERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLA 251

                          250
                   ....*....|..
gi 2462589158 1697 ELNTKLQERERE 1708
Cdd:PRK05771   252 LYEYLEIELERA 263
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 159-700 1.39e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  159 QLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQgilsQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEK 238
Cdd:COG1196    292 ELLAELARLEQDIARLEERRRELEERLEELEEELAELE----EELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  239 DQYISVLQTQVSLLKQRLRngpmnvDVLKPLPQLEPQAEVFTKEENPESDGEpvVEDGTSVKTLETLQQRVKRQENLLKR 318
Cdd:COG1196    368 LEAEAELAEAEEELEELAE------ELLEALRAAAELAAQLEELEEAEEALL--ERLERLEEELEELEEALAELEEEEEE 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  319 CKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETL 398
Cdd:COG1196    440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  399 EMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 478
Cdd:COG1196    520 RGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  479 ELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALE-KSQSEYLKISQEKEQQESLA 557
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAgGSLTGGSRRELLAALLEAEA 679

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  558 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTEL 637
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462589158  638 ESLKHQQdalwtEKLQVLKQQYQT----------EMEKLREKCE---QEKETLLKDKEIIFQAhIEEMNEKTLEKL 700
Cdd:COG1196    760 PDLEELE-----RELERLEREIEAlgpvnllaieEYEELEERYDflsEQREDLEEARETLEEA-IEEIDRETRERF 829
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1118-1743 1.40e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 1.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1118 LKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1197
Cdd:TIGR04523   24 YKNIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1198 KLKTTDEEFQSLKSshEKSNKSLEDKSLE-FKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKT------NAILSR 1270
Cdd:TIGR04523  104 DLSKINSEIKNDKE--QKNKLEVELNKLEkQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEelenelNLLEKE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1271 ISHCQHRTTKVKEALLIKTCTVSELEAqlrqLTEEQNTLNIsfqqathQLEEKENQIKSMKADIESLVTEKEALQKEGGN 1350
Cdd:TIGR04523  182 KLNIQKNIDKIKNKLLKLELLLSNLKK----KIQKNKSLES-------QISELKKQNNQLKDNIEKKQQEINEKTTEISN 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1351 QQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS------LSEKEAAISSLRKQY 1424
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNkelkseLKNQEKKLEEIQNQI 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1425 DEEK---CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQN---TVKELQIQLELKSKEAYEK 1498
Cdd:TIGR04523  331 SQNNkiiSQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNlesQINDLESKIQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1499 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMekkeSNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDI 1578
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEI----KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1579 EHKELVQKLQHFQELGEEKdnrvKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1658
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1659 AELKRKAEQKIAAIKKQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAA 1738
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKQELIDQ-KEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN 641


                   ....*
gi 2462589158 1739 YTEQE 1743
Cdd:TIGR04523  642 KLKQE 646
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1599-2118 1.55e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1599 NRVKEAEEKILT----LENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsesaaklaELKRKAEqKIAAIKK 1674
Cdd:PRK03918   175 KRRIERLEKFIKrtenIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--------ELEELKE-EIEELEK 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1675 QLlsqmeEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGcvQKT 1754
Cdd:PRK03918   246 EL-----ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR--LSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1755 YEEKISVLQRNLTEKEKLLQRVGQEKEETVsshfemrcQYQERLIKLEhaeaKQHEDQSMIGHLQEELEEKNKKYSLIVA 1834
Cdd:PRK03918   319 LEEEINGIEERIKELEEKEERLEELKKKLK--------ELEKRLEELE----ERHELYEEAKAKKEELERLKKRLTGLTP 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1835 QHVEKEGgKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDS----CLVRQKEVHRVEMEELTSKY-------- 1902
Cdd:PRK03918   387 EKLEKEL-EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkCPVCGRELTEEHRKELLEEYtaelkrie 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1903 EKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEF----KLAGAEREKQKLGKEIVRLQKDLRMLR 1978
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKynleELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1979 KEhQQELEILKKEYDQEREEKIKQEQEDLELKHNstLKQLMREFNTQLAQKEQELEMTIKETIN-----KAQEVEAELLE 2053
Cdd:PRK03918   546 KE-LEKLEELKKKLAELEKKLDELEEELAELLKE--LEELGFESVEELEERLKELEPFYNEYLElkdaeKELEREEKELK 622

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158 2054 SHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2118
Cdd:PRK03918   623 KLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEK 687
PTZ00121 PTZ00121
MAEBL; Provisional
 1531-2117 1.57e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 1.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1531 EKKESNLETELKSQTARIMELEDHITQKTIEIES-LNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKIL 1609
Cdd:PTZ00121  1082 DAKEDNRADEATEEAFGKAEEAKKTETGKAEEARkAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1610 TLENQVYSMKAE----LETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEE 1685
Cdd:PTZ00121  1162 DARKAEEARKAEdakkAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1686 QYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEE--KISVLQ 1763
Cdd:PTZ00121  1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAK 1321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1764 RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELE------EKNKKYSLIVAQHV 1837
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADaakkkaEEKKKADEAKKKAE 1401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1838 EKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKP 1917
Cdd:PTZ00121  1402 EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE 1481

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1918 TELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKL-----GKEIVRLQKDLRMLRKEHQQELEILKKEY 1992
Cdd:PTZ00121  1482 AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeeAKKADEAKKAEEKKKADELKKAEELKKAE 1561

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1993 DQEREEKIKQEQED--LELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQE--VEAELLESHQEETNQL--LKKI 2066
Cdd:PTZ00121  1562 EKKKAEEAKKAEEDknMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEakIKAEELKKAEEEKKKVeqLKKK 1641

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462589158 2067 AEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEE 2117
Cdd:PTZ00121  1642 EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1602-1910 1.82e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 1.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1602 KEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE--SESAAKLAELKRKAEQKIAAIKKQLLSQ 1679
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGeiEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1680 MEEKEEQykkgtESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIvprsaknvaaYTEQEEADSQGCVQKTYEEKI 1759
Cdd:TIGR02169  750 EQEIENV-----KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRI----------PEIQAELSKLEEEVSRIEARL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1760 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK 1839
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDEL 894

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462589158 1840 EGGKNNIQAKQN-LENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMeELTSKYEKLQALQQ 1910
Cdd:TIGR02169  895 EAQLRELERKIEeLEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEEL-SLEDVQAELQRVEE 965
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
316-543 1.91e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  316 LKRCKETIQSHKEQCTLLTSEKEALQE--QLDERLQELEKIKdlHMAEKTKLITQLRDAKNLIEQLEQDkgmviaetkrq 393
Cdd:COG4913    237 LERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLR--AALRLWFAQRRLELLEAELEELRAE----------- 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  394 mhetLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER 473
Cdd:COG4913    304 ----LARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASA 379

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  474 islqQELSRVKQEVVDVMKKSSEEQIAKLQKLHekELARKEQELTKKLQTREREFQeqmkvALEKSQSEY 543
Cdd:COG4913    380 ----EEFAALRAEAAALLEALEEELEALEEALA--EAEAALRDLRRELRELEAEIA-----SLERRKSNI 438
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 577-1138 1.97e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 1.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  577 RDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK 656
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  657 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTD 736
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  737 KMKQELEAKMDEQKNHHQQQVDsiIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 816
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAE--LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  817 ASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVcteLDAHKIQVQDLMQQLEKQNS 896
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV---KAALLLAGLRGLAGAVAVLI 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  897 EMEQKVKSLTQVYESKLEDGNkeQEQTKQILVEKENMILQMREGQKKEIEILTQK-LSAKEDSIHILNEEYETKFKNQEK 975
Cdd:COG1196    531 GVEAAYEAALEAALAAALQNI--VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRaRAALAAALARGAIGAAVDLVASDL 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  976 KMEKVKQKAKEMQ---ETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKmLEMAQANSAGISDAVSRLETNQKEQIES 1052
Cdd:COG1196    609 READARYYVLGDTllgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG-GSLTGGSRRELLAALLEAEAELEELAER 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1053 LTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFgcEKEEMNKEITWLKEEGVKQDTTLNEL 1132
Cdd:COG1196    688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE--ELLEEEELLEEEALEELPEPPDLEEL 765


                   ....*.
gi 2462589158 1133 QEQLKQ 1138
Cdd:COG1196    766 ERELER 771
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 208-518 2.93e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.67  E-value: 2.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  208 RRIAELREELQMDQQAKKHLQEEFDASLEEKDQyisvLQTQVSLLKQRLRngpmnvDVLKPLPQLEPQAEVFTKEEnpes 287
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEE----LEEELEQLRKELE------ELSRQISALRKDLARLEAEV---- 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  288 dgepvvedgtsvktlETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLit 367
Cdd:TIGR02168  743 ---------------EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL-- 805

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  368 qlrDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEEL---REQKEKSERAAFEELEKALSTA 444
Cdd:TIGR02168  806 ---DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLaaeIEELEELIEELESELEALLNER 882

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462589158  445 QKTEEARRKLKAEMDEQIKTIEKTsEEERISLQQELSRVKQEVVDVmkkSSEEQIAKLQKLHEKELARKEQELT 518
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELREL-ESKRSELRRELEELREKLAQL---ELRLEGLEVRIDNLQERLSEEYSLT 952
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1939-2166 3.05e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.67  E-value: 3.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1939 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEhQQELEILKKEYDQEREEKIKQEQEDLELKHNST--LK 2016
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER-LANLERQLEELEAQLEELESKLDELAEELAELEekLE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2017 QLMREFNtQLAQKEQELEMTIKETINKAQEVEAELLE------SHQEETNQLLKKIAEKDDDLKRTAKRYE----EILDA 2086
Cdd:TIGR02168  348 ELKEELE-SLEAELEELEAELEELESRLEELEEQLETlrskvaQLELQIASLNNEIERLEARLERLEDRRErlqqEIEEL 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2087 REEEMTAKVRDLQTQLEELQKKYQQKLEQEENPgndNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2166
Cdd:TIGR02168  427 LKKLEEAELKELQAELEELEEELEELQEELERL---EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
PRK12704 PRK12704
phosphodiesterase; Provisional
 1570-1683 3.25e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 49.01  E-value: 3.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1570 KNYNQQKDIEHKELVQKL--QHFQELgEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALE 1647
Cdd:PRK12704    52 EAIKKEALLEAKEEIHKLrnEFEKEL-RERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKE 130

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 2462589158 1648 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEK 1683
Cdd:PRK12704   131 EELEELIEEQLQELERISGLTAEEAKEILLEKVEEE 166
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1470-1693 3.43e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.67  E-value: 3.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1470 AQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET---ELKSQTA 1546
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEErreELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1547 RIMELEDHITQKTI--EIESLNEVLKNYNQQKDIE--HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAEL 1622
Cdd:COG3883     94 ALYRSGGSVSYLDVllGSESFSDFLDRLSALSKIAdaDADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462589158 1623 ETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTES 1693
Cdd:COG3883    174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 244
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1291-1826 3.77e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.27  E-value: 3.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1291 TVSELEAQLRQLTEEQNTLNISFQQATHQL----------EEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKES 1360
Cdd:PRK02224   207 RLNGLESELAELDEEIERYEEQREQARETRdeadevleehEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1361 CITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEekceLLDQVQDLS 1439
Cdd:PRK02224   287 RLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLeECRVAAQAHNEEAESLREDADD----LEERAEELR 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1440 FKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKE-ELDQQNKRFDC 1518
Cdd:PRK02224   363 EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAElEATLRTARERV 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1519 LKGEMEDDKSK-----MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHK--ELVQKLQHFQ 1591
Cdd:PRK02224   443 EEAEALLEAGKcpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRieRLEERREDLE 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1592 ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsESAAKLAELKRKAEqkiaa 1671
Cdd:PRK02224   523 ELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA-ELKERIESLERIRT----- 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1672 ikkqLLSQMEEKEEQYKKGTE--SHLSELNTKLQEREREvhiLEEKLKSVESSQSETLIvprsaknvaayteqEEADSQG 1749
Cdd:PRK02224   597 ----LLAAIADAEDEIERLREkrEALAELNDERRERLAE---KRERKRELEAEFDEARI--------------EEAREDK 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1750 CVQKTYEEKISVLQRNLTEKE-KLLQRVGQEKEE--TVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKN 1826
Cdd:PRK02224   656 ERAEEYLEQVEEKLDELREERdDLQAEIGAVENEleELEELRERREALENRVEALEALYDEAEELESMYGDLRAELRQRN 735
PTZ00121 PTZ00121
MAEBL; Provisional
 191-625 4.57e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.98  E-value: 4.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  191 EKKKLQGILSQSQDKslRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLP 270
Cdd:PTZ00121  1429 EKKKADEAKKKAEEA--KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  271 QLEPQAEVFTK-EENPESDGEPVVEDGTSVKTLETLQQRVKRQEnlLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQ 349
Cdd:PTZ00121  1507 EAKKKADEAKKaEEAKKADEAKKAEEAKKADEAKKAEEKKKADE--LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  350 ELEKIKDLHMAEKTKLITQLRDAKnlIEQLEQdkgmviAETKRQMHETLEMKEEE---IAQLRSRIKQMTTQGEELREQK 426
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYEEEKKMK--AEEAKK------AEEAKIKAEELKKAEEEkkkVEQLKKKEAEEKKKAEELKKAE 1656

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  427 EKSERAAFEELEKALSTAQKTEEARrklKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVV---DVMKKSSEEQIAKLQ 503
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDKKKAEEAK---KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkkaEELKKAEEENKIKAE 1733

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  504 KLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK-----ISQEKEQQESLALEELELQKKAILTESENkLRD 578
Cdd:PTZ00121  1734 EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKekeavIEEELDEEDEKRRMEVDKKIKDIFDNFAN-IIE 1812

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 2462589158  579 LQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKE 625
Cdd:PTZ00121  1813 GGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNE 1859
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
342-905 4.58e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 4.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  342 EQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHEtLEMKEEEIAQLRSRIKQMTTQGEE 421
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSE-LPELREELEKLEKEVKELEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  422 LREQKEK--SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIE--KTSEEERISLQQELSRVKQEVVDVMKKSS-- 495
Cdd:PRK03918   240 IEELEKEleSLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSrl 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  496 EEQIAKLQKLHEK--ELARKEQELTKKLQTREREFQEqmkvaLEKSQSEYLKISQEKEQqeslaleeLELQKKAILTESE 573
Cdd:PRK03918   320 EEEINGIEERIKEleEKEERLEELKKKLKELEKRLEE-----LEERHELYEEAKAKKEE--------LERLKKRLTGLTP 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  574 NKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITV---MVEKHKTELESLKHQQDALWTE 650
Cdd:PRK03918   387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCgreLTEEHRKELLEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  651 KLQVLKQQyqteMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR-HKLEEELS 729
Cdd:PRK03918   467 ELKEIEEK----ERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKlIKLKGEIK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  730 VLKDQTDKmKQELE---AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKhLKEHQAHVENLEAD 806
Cdd:PRK03918   543 SLKKELEK-LEELKkklAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELEREEKE 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  807 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERilLTKQVAEVEAQKKdvctELDAHKIQVQD 886
Cdd:PRK03918   621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLE--LSRELAGLRAELE----ELEKRREEIKK 694

                          570
                   ....*....|....*....
gi 2462589158  887 LMQQLEKQNSEMEQKVKSL 905
Cdd:PRK03918   695 TLEKLKEELEEREKAKKEL 713
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 477-805 4.91e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.58  E-value: 4.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  477 QQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQeltkkLQTREREFQEQMKVALEKSQsEYLKISQEKEQQESL 556
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAE-----MDRQAAIYAEQERMAMERER-ELERIRQEERKRELE 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  557 ALEElelQKKAILTESENKLRDLQQEAETYRTRIL-ELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEitvmvEKHKT 635
Cdd:pfam17380  364 RIRQ---EEIAMEISRMRELERLQMERQQKNERVRqELEAARKVKILEEERQRKIQQQKVEMEQIRAEQE-----EARQR 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  636 ELESLKHQQdALWTEKLQVLKQQYQTEMEKLRE-KCEQEKETLLKDKEIIFQAHIEEMNEKTLEKldvkqtELESLSSEL 714
Cdd:pfam17380  436 EVRRLEEER-AREMERVRLEEQERQQQVERLRQqEEERKRKKLELEKEKRDRKRAEEQRRKILEK------ELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  715 SEVLKARHKLEEElsvLKDQTDKMKQELEAKMDEQKNHHQQQVdsiikEHEVSIQRTEKALKDQINQLELLLKERD--KH 792
Cdd:pfam17380  509 IEEERKRKLLEKE---MEERQKAIYEEERRREAEEERRKQQEM-----EERRRIQEQMRKATEERSRLEAMEREREmmRQ 580

                          330
                   ....*....|...
gi 2462589158  793 LKEHQAHVENLEA 805
Cdd:pfam17380  581 IVESEKARAEYEA 593
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 303-977 6.71e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 6.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  303 ETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLdeRLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ---- 378
Cdd:TIGR00618  215 DTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL--KKQQLLKQLRARIEELRAQEAVLEETQERINRarka 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  379 ----LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKL 454
Cdd:TIGR00618  293 aplaAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISC 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  455 KAEMDEQ----IKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHekelARKEQELTKKLQTREREF-- 528
Cdd:TIGR00618  373 QQHTLTQhihtLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAH----AKKQQELQQRYAELCAAAit 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  529 -QEQMKVALEKSQSEYLKISQEKEQQESLALEELElQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 607
Cdd:TIGR00618  449 cTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHL-QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  608 SKDLAVHLEaeknkhnkeitvmVEKHKTELESLKHQQDALwTEKLQVLKQQYQTEMEKLREKCEQEKET-----LLKDKE 682
Cdd:TIGR00618  528 RRMQRGEQT-------------YAQLETSEEDVYHQLTSE-RKQRASLKEQMQEIQQSFSILTQCDNRSkedipNLQNIT 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  683 IIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKnHHQQQVDSIIK 762
Cdd:TIGR00618  594 VRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVR-EHALSIRVLPK 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  763 EHEVSIQRTEKAL----------KDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDvfQSYQSATH 832
Cdd:TIGR00618  673 ELLASRQLALQKMqsekeqltywKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALN--QSLKELMH 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  833 EQTKAYEEQLAQLQQKLLDLETERILLTkqvaeveaQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESK 912
Cdd:TIGR00618  751 QARTVLKARTEAHFNNNEEVTAALQTGA--------ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQ 822

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158  913 LEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKM 977
Cdd:TIGR00618  823 CETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1266-1828 6.89e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 6.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1266 AILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQlteEQNTLNISFQQATHQLEEKENQ--------IKSMKADIE-- 1335
Cdd:pfam12128  273 LIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG---ELSAADAAVAKDRSELEALEDQhgafldadIETAAADQEql 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1336 -SLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKE 1414
Cdd:pfam12128  350 pSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLE 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1415 AAISSLRkqydEEKCELLDQVQDLSFKVD--TLSKEKISALEQVDDWSNKfsewkkkAQSRFTQHQNTVKELQIQLELKS 1492
Cdd:pfam12128  430 AGKLEFN----EEEYRLKSRLGELKLRLNqaTATPELLLQLENFDERIER-------AREEQEAANAEVERLQSELRQAR 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1493 KEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELED-HITQKTIEI--ESLNEVL 1569
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELlHRTDLDPEVwdGSVGGEL 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1570 KNYNQQKDIEHKELVQKLQHFQELGEEKD---NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1646
Cdd:pfam12128  579 NLYGVKLDLKRIDVPEWAASEEELRERLDkaeEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRL 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1647 EDRLESESAAK---LAELKRKAEQKIAAIKKQlLSQMEEKEEQYKKGTESHLSELNTKLQEREREVhilEEKLKSVESSQ 1723
Cdd:pfam12128  659 FDEKQSEKDKKnkaLAERKDSANERLNSLEAQ-LKQLDKKHQAWLEEQKEQKREARTEKQAYWQVV---EGALDAQLALL 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1724 SETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQY----QERLI 1799
Cdd:pfam12128  735 KAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWlqrrPRLAT 814

                          570       580
                   ....*....|....*....|....*....
gi 2462589158 1800 KLEHAEAKQHEDQSMIGHLQEELEEKNKK 1828
Cdd:pfam12128  815 QLSNIERAISELQQQLARLIADTKLRRAK 843
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 579-1231 8.72e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.91  E-value: 8.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  579 LQQEAETYRTRILEL-------------ESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQD 645
Cdd:pfam12128  246 LQQEFNTLESAELRLshlhfgyksdetlIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  646 ALWTEKLQVLKQQYQTEmeklreKCEQEKETLlkdkeiiFQAHIEEMNEKtLEKLDVKQteLESLSSELSEVLKARHKLE 725
Cdd:pfam12128  326 ALEDQHGAFLDADIETA------AADQEQLPS-------WQSELENLEER-LKALTGKH--QDVTAKYNRRRSKIKEQNN 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  726 EELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKA----------LKDQINQL----ELLLKERDK 791
Cdd:pfam12128  390 RDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEeyrlksrlgeLKLRLNQAtatpELLLQLENF 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  792 -----HLKEHQ----AHVENLEADIKRSEG-------ELQQASAKLDVFQSYQSATHEQTKA---------YEEQLAQLQ 846
Cdd:pfam12128  470 derieRAREEQeaanAEVERLQSELRQARKrrdqaseALRQASRRLEERQSALDELELQLFPqagtllhflRKEAPDWEQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  847 QKLLDLETERILLTKQVAEV-EAQKKDVCT----ELDAHKIQVQDLMQqlekqnseMEQKVKSLTQVYESKLEDGNKEQE 921
Cdd:pfam12128  550 SIGKVISPELLHRTDLDPEVwDGSVGGELNlygvKLDLKRIDVPEWAA--------SEEELRERLDKAEEALQSAREKQA 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  922 QTKQILVEKENmilQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQ--ETLKKKLLDQE 999
Cdd:pfam12128  622 AAEEQLVQANG---ELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNslEAQLKQLDKKH 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1000 AKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELN--DVISIWEKKLNQQAE 1077
Cdd:pfam12128  699 QAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLAslGVDPDVIAKLKREIR 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1078 ELQEIHEiQLQEKEQEVAELKQkillfgCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNS-LAQDETKLKAh 1156
Cdd:pfam12128  779 TLERKIE-RIAVRRQEVLRYFD------WYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLrRAKLEMERKA- 850

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158 1157 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSeLTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1231
Cdd:pfam12128  851 SEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGS-IGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHS 924
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 634-1716 8.83e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 48.12  E-value: 8.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  634 KTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNeKTLEKLDVKQTELESLSSE 713
Cdd:TIGR01612  695 KAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKDLN-KILEDFKNKEKELSNKIND 773

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  714 LSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI----IKEHEVSIQRTE-KALKDQI-NQLELLLK 787
Cdd:TIGR01612  774 YAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIktisIKEDEIFKIINEmKFMKDDFlNKVDKFIN 853

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  788 ERDKHLKEHQAHVENLEADIKRSEGEL--QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILL-TKQVA 864
Cdd:TIGR01612  854 FENNCKEKIDSEHEQFAELTNKIKAEIsdDKLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVDEYIKICEnTKESI 933

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  865 EVEAQKKDVCTELDAHKIQVQDLMQQLEK------QNSEMEQKV---KSLTQVYESKLEDGNKEQEQTKQILVE-----K 930
Cdd:TIGR01612  934 EKFHNKQNILKEILNKNIDTIKESNLIEKsykdkfDNTLIDKINeldKAFKDASLNDYEAKNNELIKYFNDLKAnlgknK 1013

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  931 ENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEmqetlkkkLLDQEAKLKKELENTA 1010
Cdd:TIGR01612 1014 ENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIE--------LLNKEILEEAEINITN 1085

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1011 L-ELSQKEKQFN----AKMLEMAQANSAG-ISDAVSRLETNQKEQIESLTEVHRRELNDVisiweKKLNQQAEELQEIHE 1084
Cdd:TIGR01612 1086 FnEIKEKLKHYNfddfGKEENIKYADEINkIKDDIKNLDQKIDHHIKALEEIKKKSENYI-----DEIKAQINDLEDVAD 1160

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1085 IQLQEKEQEVAELKQKILLFGCEK-----EEMNKEITWLKEEGvKQDTTLNELQEQLKQKSAHVNSL---AQDETKLKAH 1156
Cdd:TIGR01612 1161 KAISNDDPEEIEKKIENIVTKIDKkkniyDEIKKLLNEIAEIE-KDKTSLEEVKGINLSYGKNLGKLfleKIDEEKKKSE 1239

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1157 -----LEKLEVDLNKSLKentflQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1231
Cdd:TIGR01612 1240 hmikaMEAYIEDLDEIKE-----KSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDF 1314

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1232 EELAIQLDICCKKTEALLEAKTNelinisSSKTNAILSRISHCQHrttkvkealLIKTCTVSELEAQLRQLTEEQNTLNi 1311
Cdd:TIGR01612 1315 SEESDINDIKKELQKNLLDAQKH------NSDINLYLNEIANIYN---------ILKLNKIKKIIDEVKEYTKEIEENN- 1378

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1312 sfQQATHQLEEKENQIKSMKADIeslvtekealqkeggNQQQAASEKESCITQlkKELSENINAVTLMKEELKEKKVEIS 1391
Cdd:TIGR01612 1379 --KNIKDELDKSEKLIKKIKDDI---------------NLEECKSKIESTLDD--KDIDECIKKIKELKNHILSEESNID 1439

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1392 SLSKQLTDLNvqlqNSISLSEKEAAISSLRKQYDEeKCELLDQVQDLSFKVDTLsKEKISALEQVDDWSNKFSEWKKKAQ 1471
Cdd:TIGR01612 1440 TYFKNADENN----ENVLLLFKNIEMADNKSQHIL-KIKKDNATNDHDFNINEL-KEHIDKSKGCKDEADKNAKAIEKNK 1513

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1472 SRFTQHQNTVKEL---QIQLELKSKEAYEKDEQINLLKEELDQQNKRFdcLKGEMEDDKSKMEKKEsnlETELKSQTARI 1548
Cdd:TIGR01612 1514 ELFEQYKKDVTELlnkYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFI--LEAEKSEQKIKEIKKE---KFRIEDDAAKN 1588

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1549 MELEDHITQKTIEIESL-NEVLKNYNQQKDI-----EHKELVQKLQHFQElgEEKDNRVKEAEEKILTLENQVYSMKAE- 1621
Cdd:TIGR01612 1589 DKSNKAAIDIQLSLENFeNKFLKISDIKKKIndclkETESIEKKISSFSI--DSQDTELKENGDNLNSLQEFLESLKDQk 1666

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1622 --LETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSElN 1699
Cdd:TIGR01612 1667 knIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDP-N 1745

                         1130
                   ....*....|....*..
gi 2462589158 1700 TKLQEREREVHILEEKL 1716
Cdd:TIGR01612 1746 EKLEEYNTEIGDIYEEF 1762
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
369-840 1.01e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 1.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  369 LRDAKNLIEQLEQDkgmvIAETK-RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSE---------RAAFEELE 438
Cdd:PRK02224   182 LSDQRGSLDQLKAQ----IEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADevleeheerREELETLE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  439 KALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE-------------------ERISLQQE-LSRVKQEVVDVMkksseEQ 498
Cdd:PRK02224   258 AEIEDLRETIAETEREREELAEEVRDLRERLEEleeerddllaeaglddadaEAVEARREeLEDRDEELRDRL-----EE 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  499 IAKLQKLHEKElARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK-----AILTESE 573
Cdd:PRK02224   333 CRVAAQAHNEE-AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdapVDLGNAE 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  574 NKLRDLQQEAETYRTRILELESSLeKSLQENKNQSKDLavhLEA----------EKNKHNKEIT---VMVEKHKTELESL 640
Cdd:PRK02224   412 DFLEELREERDELREREAELEATL-RTARERVEEAEAL---LEAgkcpecgqpvEGSPHVETIEedrERVEELEAELEDL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  641 KHQQDALwTEKLQVLKQQYQTE--MEKLREKCEQEKEtLLKDKEiifqAHIEEMNEKTLEKLDVKQTELESLSSELSEVL 718
Cdd:PRK02224   488 EEEVEEV-EERLERAEDLVEAEdrIERLEERREDLEE-LIAERR----ETIEEKRERAEELRERAAELEAEAEEKREAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  719 KARHKLEEELSVLKdqtdkmkqELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKaLKDQINQLELLLKERDKHLKEH 796
Cdd:PRK02224   562 EAEEEAEEAREEVA--------ELNSKLAELKERIESleRIRTLLAAIADAEDEIER-LREKREALAELNDERRERLAEK 632

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 2462589158  797 QAHVENLEADIkrSEGELQQASAKLDVFQSYQSATHEQTKAYEE 840
Cdd:PRK02224   633 RERKRELEAEF--DEARIEEAREDKERAEEYLEQVEEKLDELRE 674
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 388-609 1.23e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  388 AETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAfEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 467
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  468 TSEE------ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLheKELARKEQELTKKLQTREREFQEQmKVALEKSQS 541
Cdd:COG4942     98 ELEAqkeelaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL--KYLAPARREQAEELRADLAELAAL-RAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462589158  542 EyLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSK 609
Cdd:COG4942    175 E-LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
138-425 1.54e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  138 PSDMDSEAEDLVGNSDSLNK-EQLIQRLRRMERSLS---SYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLR-RIAE 212
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERaHEALEDAREQIELLEpirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEaELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  213 LREELQMDQQAKKHLQEEFDASLEEKDQyisvlqtqvsLLKQRLRNGpmnVDVLKPLPQLEPQAEvftkeenpesdgepv 292
Cdd:COG4913    300 LRAELARLEAELERLEARLDALREELDE----------LEAQIRGNG---GDRLEQLEREIERLE--------------- 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  293 vedgtsvKTLETLQQRVKRQENLLKRCKETIQSHKEqctlltsEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDA 372
Cdd:COG4913    352 -------RELEERERRRARLEALLAALGLPLPASAE-------EFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462589158  373 KNLIEQLEQdkgmviaetkrqmhetlemkeeEIAQLRSRIKQMTTQGEELREQ 425
Cdd:COG4913    418 RRELRELEA----------------------EIASLERRKSNIPARLLALRDA 448
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 975-1722 1.97e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.96  E-value: 1.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  975 KKMEKVKQKAKEMQETL--KKKLLDQEAKLKKELENTALELSQKEKQfnakmLEMAQANSAGISDAVSRLETNQKEQies 1052
Cdd:TIGR00606  210 KYLKQYKEKACEIRDQItsKEAQLESSREIVKSYENELDPLKNRLKE-----IEHNLSKIMKLDNEIKALKSRKKQM--- 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1053 ltEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNEL 1132
Cdd:TIGR00606  282 --EKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRH 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1133 QEQLKQKSAHVNSLAqdetkLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSS 1212
Cdd:TIGR00606  360 QEHIRARDSLIQSLA-----TRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1213 HEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALL 1286
Cdd:TIGR00606  435 KKGLGRTIELKKEILEKKQEELKFvikelqQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1287 IKTCTVSELEAQLRQLTEEQNTLnisfQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK 1366
Cdd:TIGR00606  515 RKLRKLDQEMEQLNHHTTTRTQM----EMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTR 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1367 KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCEL-------------LD 1433
Cdd:TIGR00606  591 DRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRamlagatavysqfIT 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1434 QVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQN 1513
Cdd:TIGR00606  671 QLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELR 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1514 KRFDCLKGEMEDDKSKMEKKESNLETELKSQTA----------------RIMELEDHITQKTIEIESLN-----EVLKNY 1572
Cdd:TIGR00606  751 NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESakvcltdvtimerfqmELKDVERKIAQQAAKLQGSDldrtvQQVNQE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1573 NQQKDIEHKELVQKLQHFQELGEE----------KDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEE 1642
Cdd:TIGR00606  831 KQEKQHELDTVVSKIELNRKLIQDqqeqiqhlksKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQ 910

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1643 LKALEDRLE------SESAAKLAELKRKAEQKIAAIKKQ----------LLSQMEEKEEQYKKGTESHLSELNTKLQERE 1706
Cdd:TIGR00606  911 DSPLETFLEkdqqekEELISSKETSNKKAQDKVNDIKEKvknihgymkdIENKIQDGKDDYLKQKETELNTVNAQLEECE 990

                          810
                   ....*....|....*.
gi 2462589158 1707 REVHILEEKLKSVESS 1722
Cdd:TIGR00606  991 KHQEKINEDMRLMRQD 1006
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 367-520 3.09e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 46.23  E-value: 3.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  367 TQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMttqgeelrEQKEKSERAAFEELekalstaqk 446
Cdd:COG0542    411 EELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEAL--------KARWEAEKELIEEI--------- 473

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  447 teearRKLKAEMDEQ---IKTIEKTSEEERISLQQELSRVKQEVvdvmkksSEEQIAK---------LQKLHEKE---LA 511
Cdd:COG0542    474 -----QELKEELEQRygkIPELEKELAELEEELAELAPLLREEV-------TEEDIAEvvsrwtgipVGKLLEGErekLL 541


                   ....*....
gi 2462589158  512 RKEQELTKK 520
Cdd:COG0542    542 NLEEELHER 550
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
297-681 3.31e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.19  E-value: 3.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  297 TSVKTLETLQQRVKRQENL---LKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAK 373
Cdd:PRK02224   231 QARETRDEADEVLEEHEERreeLETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAE 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  374 NLIEQLE--QDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKekseraafEELEKALSTAQKTEEAR 451
Cdd:PRK02224   311 AVEARREelEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA--------AELESELEEAREAVEDR 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  452 RKLKAEMDEQIKTIEKT----------SEEERISLQQELSRVKQEVVDVMK--KSSEEQIAKLQKLHEkelARKEQELTK 519
Cdd:PRK02224   383 REEIEELEEEIEELRERfgdapvdlgnAEDFLEELREERDELREREAELEAtlRTARERVEEAEALLE---AGKCPECGQ 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  520 KLQTRER-EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTES-ENKLRDLQQEAETYRTRILELESSL 597
Cdd:PRK02224   460 PVEGSPHvETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERlEERREDLEELIAERRETIEEKRERA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  598 EkSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKT---ELESLKHQQDALWT-EKLQVLKQQYQTEMEKLREKCEQ- 672
Cdd:PRK02224   540 E-ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAElnsKLAELKERIESLERiRTLLAAIADAEDEIERLREKREAl 618

                          410
                   ....*....|
gi 2462589158  673 -EKETLLKDK 681
Cdd:PRK02224   619 aELNDERRER 628
PRK12704 PRK12704
phosphodiesterase; Provisional
 1067-1197 3.33e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 3.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1067 IWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGceKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSL 1146
Cdd:PRK12704    24 VRKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEA--KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462589158 1147 AQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1197
Cdd:PRK12704   102 LELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTA 152
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1415-2042 3.64e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 3.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1415 AAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVddwsnkFSEWKKKAQSRFTQHQNTVKELQIQLELKSKE 1494
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL------LQQHQDRIEQLISEHEVEITGLTEKASSARSQ 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1495 AYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkeSNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQ 1574
Cdd:pfam15921  294 ANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLR---SELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQ 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1575 qkdiEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESES 1654
Cdd:pfam15921  371 ----ESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1655 AAKLAELKRKAE--QKIAAIKKQLLSQMEE-----KEEQYKKGT----ESHLSELNTKLQEREREVHILEEKLKSVESSQ 1723
Cdd:pfam15921  447 ERQMAAIQGKNEslEKVSSLTAQLESTKEMlrkvvEELTAKKMTlessERTVSDLTASLQEKERAIEATNAEITKLRSRV 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1724 SETLIVPRSAKNVAAYTEQEEADSQGcVQKTYEEKISVLQRNLTEKEKLLQRVGQ----------EKEETVSSHFEMRCQ 1793
Cdd:pfam15921  527 DLKLQELQHLKNEGDHLRNVQTECEA-LKLQMAEKDKVIEILRQQIENMTQLVGQhgrtagamqvEKAQLEKEINDRRLE 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1794 YQERLIKLEHAEAKQHEDQSMIGHLQEEleeknkKYSLIVAQHVEKEGGKNNIQAKQNL----ENVFDDVQKTLQEKELT 1869
Cdd:pfam15921  606 LQEFKILKDKKDAKIRELEARVSDLELE------KVKLVNAGSERLRAVKDIKQERDQLlnevKTSRNELNSLSEDYEVL 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1870 CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLvqpkllSNMEAQHNDL 1949
Cdd:pfam15921  680 KRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI------DALQSKIQFL 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1950 EFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEILKKEydqerEEKIKQEQEDLELKHNSTLKQLMREFNTQL 2026
Cdd:pfam15921  754 EEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKmagELEVLRSQ-----ERRLKEKVANMEVALDKASLQFAECQDIIQ 828

                          650
                   ....*....|....*.
gi 2462589158 2027 AQKEQELEMTIKETIN 2042
Cdd:pfam15921  829 RQEQESVRLKLQHTLD 844
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 870-1101 3.83e-04

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 45.61  E-value: 3.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  870 KKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES-KLEDGNKEQEQtkQILVEKENMILQMREGQKKEIEIL 948
Cdd:pfam09726  393 KPDALVRLEQDIKKLKAELQASRQTEQELRSQISSLTSLERSlKSELGQLRQEN--DLLQTKLHNAVSAKQKDKQTVQQL 470

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  949 TQKLSAKEDSI----HILNEEYETKFKNQEKKMEKVKQKA---KEMQETLKKKLLDQEAKLKK-------------ELEN 1008
Cdd:pfam09726  471 EKRLKAEQEARasaeKQLAEEKKRKKEEEATAARAVALAAasrGECTESLKQRKRELESEIKKlthdiklkeeqirELEI 550

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1009 TALELSQKEKqfNAKMLEMAQANSAGISDAVSRLEtnqkeqiESLTEVHRRELnDVISiwekKLNQQAEELqEIHEIQLQ 1088
Cdd:pfam09726  551 KVQELRKYKE--SEKDTEVLMSALSAMQDKNQHLE-------NSLSAETRIKL-DLFS----ALGDAKRQL-EIAQGQIY 615

                          250
                   ....*....|...
gi 2462589158 1089 EKEQEVAELKQKI 1101
Cdd:pfam09726  616 QKDQEIKDLKQKI 628
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 334-531 3.94e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  334 TSEKEALQEQLDE---RLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDkgmvIAETKRQMHETlemkEEEIAQLRS 410
Cdd:COG4942     19 ADAAAEAEAELEQlqqEIAELEKELAALKKEEKALLKQLAALERRIAALARR----IRALEQELAAL----EAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  411 RIKQMTTQGEELREQKEKSERAA-----------------FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE-- 471
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALyrlgrqpplalllspedFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEle 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462589158  472 -----------ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLheKELARKEQELTKKLQTREREFQEQ 531
Cdd:COG4942    171 aeraeleallaELEEERAALEALKAERQKLLARLEKELAELAAEL--AELQQEAEELEALIARLEAEAAAA 239
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
375-535 5.21e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 45.23  E-value: 5.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  375 LIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQ-KEKSERAafEELEKALSTAQKteEARRK 453
Cdd:COG2433    385 LIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAElEEKDERI--ERLERELSEARS--EERRE 460

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  454 LKaemdeqiKTIEKTSEEERIS-LQQELSRVKQEVvdvmkKSSEEQIAKLQKLHEKElARKEQELTKKLQ--TRE--REF 528
Cdd:COG2433    461 IR-------KDREISRLDREIErLERELEEERERI-----EELKRKLERLKELWKLE-HSGELVPVKVVEkfTKEaiRRL 527


                   ....*..
gi 2462589158  529 QEQMKVA 535
Cdd:COG2433    528 EEEYGLK 534
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 719-907 5.38e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 5.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  719 KARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQqvdsiIKEHEVSIQRTEKALKD---QINQLELLLKERDKHLKE 795
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ-----LAALERRIAALARRIRAleqELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  796 HQAHVENLEADIKR------------------SEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI 857
Cdd:COG4942     95 LRAELEAQKEELAEllralyrlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462589158  858 LLTKQVAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 907
Cdd:COG4942    175 ELEALLAELEEERA----ALEALKAERQKLLARLEKELAELAAELAELQQ 220
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1563-1715 6.61e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 6.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1563 ESLNEVLKnynqqkDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVysmkAELETKKKELEHvnlSVKSKEEE 1642
Cdd:COG2433    376 LSIEEALE------ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQV----ERLEAEVEELEA---ELEEKDER 442

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462589158 1643 LKALEDRLESESAAKLAELKRKAE-QKIAAIKKQLLSQMEEKEEqykkgtesHLSELNTKLqEREREVHILEEK 1715
Cdd:COG2433    443 IERLERELSEARSEERREIRKDREiSRLDREIERLERELEEERE--------RIEELKRKL-ERLKELWKLEHS 507
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 300-1743 7.20e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 45.04  E-value: 7.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  300 KTLETLQQRVKRQENLLKRCKETIQSHKE--QCTLLTSEKEALQEQLDERLQELEKIKDLHmAEKTKLITQLRDAKNLIE 377
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQINDLEDvaDKAISNDDPEEIEKKIENIVTKIDKKKNIY-DEIKKLLNEIAEIEKDKT 1207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  378 QLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE-------------------ELE 438
Cdd:TIGR01612 1208 SLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEmgiemdikaemetfnishdDDK 1287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  439 KALSTAQKTEEARRKLKaemDEQIKTIEKTSEEERI-----SLQQELSRVKQEVVDVMKKSSE----EQIAKLQKLheKE 509
Cdd:TIGR01612 1288 DHHIISKKHDENISDIR---EKSLKIIEDFSEESDIndikkELQKNLLDAQKHNSDINLYLNEianiYNILKLNKI--KK 1362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  510 LARKEQELTKKLQtrerEFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAIltesenklRDLQQEAETYRTR 589
Cdd:TIGR01612 1363 IIDEVKEYTKEIE----ENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKDI--------DECIKKIKELKNH 1430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  590 ILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEK-------HKTELESLKHQQD------------ALWTE 650
Cdd:TIGR01612 1431 ILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKkdnatndHDFNINELKEHIDkskgckdeadknAKAIE 1510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  651 KLQVLKQQYQTEMEKLREK-----CEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 725
Cdd:TIGR01612 1511 KNKELFEQYKKDVTELLNKysalaIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDK 1590

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  726 EELSVLKDQTDkmKQELEAKMDEQKNhHQQQVDSIIKEHEvSIQRTEKALkdQINQLELLLKERDKHLKEHQAHVENLEA 805
Cdd:TIGR01612 1591 SNKAAIDIQLS--LENFENKFLKISD-IKKKINDCLKETE-SIEKKISSF--SIDSQDTELKENGDNLNSLQEFLESLKD 1664

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  806 DIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVaeVEAQKKDVCTELDAHKIQVQ 885
Cdd:TIGR01612 1665 QKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKEL--IEPTIENLISSFNTNDLEGI 1742

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  886 DLMQQLEKQNSEMEQKVKSLTQVYE---SKLEDGNKEQ---EQTKQILVEKENMILQMREGQKK-----------EIEIL 948
Cdd:TIGR01612 1743 DPNEKLEEYNTEIGDIYEEFIELYNiiaGCLETVSKEPityDEIKNTRINAQNEFLKIIEIEKKsksylddieakEFDRI 1822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  949 TQKLSAKEDSIHI-LNEEYET---KFKNQEKKMEKVKQKAKE---------MQETLKKKLLDQEAKLKKELENTALELSQ 1015
Cdd:TIGR01612 1823 INHFKKKLDHVNDkFTKEYSKineGFDDISKSIENVKNSTDEnllfdilnkTKDAYAGIIGKKYYSYKDEAEKIFINISK 1902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1016 KEKQFNAKMlemaqANSAGIS-------DAVSRLETNQKEQI----------ESLTEVhRRELNDVISIWEKKLNQQAEE 1078
Cdd:TIGR01612 1903 LANSINIQI-----QNNSGIDlfdniniAILSSLDSEKEDTLkfipspekepEIYTKI-RDSYDTLLDIFKKSQDLHKKE 1976

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1079 LQEIHEI----QLQEKEQEVAELKQKILLFGCEKEEMNKEITWLkeegVKQDTTLNELQEQLKQKSAHVNSLAQDETKLK 1154
Cdd:TIGR01612 1977 QDTLNIIfenqQLYEKIQASNELKDTLSDLKYKKEKILNDVKLL----LHKFDELNKLSCDSQNYDTILELSKQDKIKEK 2052

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1155 A-----HLEKLEVDLNKSLKENTFLQ-----EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKS 1224
Cdd:TIGR01612 2053 IdnyekEKEKFGIDFDVKAMEEKFDNdikdiEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNTEIKIIEDKI 2132

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1225 LEFKKLSEELAIQLDICCKKTEA-LLEAKTNELINISSSKTNAilsrishcqhrttkvkeallikTCTVSELEAQLRQLT 1303
Cdd:TIGR01612 2133 IEKNDLIDKLIEMRKECLLFSYAtLVETLKSKVINHSEFITSA----------------------AKFSKDFFEFIEDIS 2190

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1304 EEQNTlNISFQQATHQLEEKENQIKSMKADIESlvTEKEALQKEggnqqQAASEKESCITQLKKELSENINAVTLMKEEL 1383
Cdd:TIGR01612 2191 DSLND-DIDALQIKYNLNQTKKHMISILADATK--DHNNLIEKE-----KEATKIINNLTELFTIDFNNADADILHNNKI 2262

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1384 kekkveisslskQLTDLNVQLQNSislsekeaaISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEkisaleqvddwsnkF 1463
Cdd:TIGR01612 2263 ------------QIIYFNSELHKS---------IESIKKLYKKINAFKLLNISHINEKYFDISKE--------------F 2307

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1464 SEWKKKAQSRFTQHQNTVKELqiqlelkskEAYEKDEQINLLKEELDQQNKRFDCLKgEMEDDKSKMEKKESNLETELKS 1543
Cdd:TIGR01612 2308 DNIIQLQKHKLTENLNDLKEI---------DQYISDKKNIFLHALNENTNFNFNALK-EIYDDIINRENKADEIENINNK 2377

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1544 QTARIMELEDHITQKTIEIESL----------NEVLKNYNQQKDIEH-----KELVQKLQHFQELgeekDNRVKEAEEKI 1608
Cdd:TIGR01612 2378 ENENIMQYIDTITKLTEKIQDIlifvttyendNNIIKQHIQDNDENDvskikDNLKKTIQSFQEI----LNKIDEIKAQF 2453

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1609 LTlENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYK 1688
Cdd:TIGR01612 2454 YG-GNNINNIIITISQNANDVKNHFSKDLTIENELIQIQKRLEDIKNAAHEIRSEQITKYTNAIHNHIEEQFKKIENNSN 2532

                         1530      1540      1550      1560      1570
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462589158 1689 KGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQE 1743
Cdd:TIGR01612 2533 KDEVYKINEIDNIIEKIINYNKEPEVKLHAIIDNKNEFASIIPDIKNLIALIESE 2587
46 PHA02562
endonuclease subunit; Provisional
 1131-1374 7.56e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 7.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1131 ELQEQLKQKSAHVNSLaqdETKLKAHlEKLEVDLNKSLKEN-TFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSL 1209
Cdd:PHA02562   178 ELNQQIQTLDMKIDHI---QQQIKTY-NKNIEEQRKKNGENiARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1210 KSSHEKSNKSLEDKSLEFKKLSEELAIQLD--ICCKKTEALLEakTNELINisssktnAILSRISHCQHRTTKVKEAlli 1287
Cdd:PHA02562   254 SAALNKLNTAAAKIKSKIEQFQKVIKMYEKggVCPTCTQQISE--GPDRIT-------KIKDKLKELQHSLEKLDTA--- 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1288 ktctVSELEAQLRQLTEEQNTLNisfqqathqleEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKK 1367
Cdd:PHA02562   322 ----IDELEEIMDEFNEQSKKLL-----------ELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386


                   ....*..
gi 2462589158 1368 ELSENIN 1374
Cdd:PHA02562   387 ELDKIVK 393
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1129-1720 7.99e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 7.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1129 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELkmlaEEDKRKVSELTSKLKTTDEEFQS 1208
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPEL----REELEKLEKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1209 LK---SSHEKSNKSLEDKSLEFKKLSEELaiqldiccKKTEALLEAKTNELINISSSKTNAIlsRISHCQHRTTKVKEAL 1285
Cdd:PRK03918   243 LEkelESLEGSKRKLEEKIRELEERIEEL--------KKEIEELEEKVKELKELKEKAEEYI--KLSEFYEEYLDELREI 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1286 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLvteKEALQKEGGNQQQAASEKESCITQL 1365
Cdd:PRK03918   313 EKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY---EEAKAKKEELERLKKRLTGLTPEKL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1366 KKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNvqlQNSISLSEKEAAISSLRKQYDEEkcELLDQVQDLSFKVDTL 1445
Cdd:PRK03918   390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELK---KAIEELKKAKGKCPVCGRELTEE--HRKELLEEYTAELKRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1446 SKEKISALEQVDDWSNKFSEWKK--KAQSRFTQHQNTVKELqiqlelksKEAYEKDEQINLlkEELDQQNKRFDCLKGEM 1523
Cdd:PRK03918   465 EKELKEIEEKERKLRKELRELEKvlKKESELIKLKELAEQL--------KELEEKLKKYNL--EELEKKAEEYEKLKEKL 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1524 eddkSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKdNRVKE 1603
Cdd:PRK03918   535 ----IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEY-LELKD 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1604 AEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQlLSQMEEK 1683
Cdd:PRK03918   610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAE-LEELEKR 688

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 2462589158 1684 EEQYKKGTEShLSELNTKLQEREREVHILEEKLKSVE 1720
Cdd:PRK03918   689 REEIKKTLEK-LKEELEEREKAKKELEKLEKALERVE 724
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1152-2010 8.25e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 8.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1152 KLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEfKKLS 1231
Cdd:pfam02463  170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE-LLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1232 EELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNI 1311
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1312 SFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEIS 1391
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1392 S---LSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDwSNKFSEWKK 1468
Cdd:pfam02463  409 LlleLARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ-LVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1469 KAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTA-- 1546
Cdd:pfam02463  488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKlv 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1547 RIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAE------EKILTLENQVYSMKA 1620
Cdd:pfam02463  568 RALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEgilkdtELTKLKESAKAKESG 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1621 ELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNT 1700
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1701 KLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKisvlQRNLTEKEKLLQRVGQEK 1780
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEK----LKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1781 EETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMigHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQ 1860
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEE--LALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1861 KTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRnkptelleenteEKSKSHLVQPKLLS 1940
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE------------EPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1941 NMEAQHNDLEFKLAGAEREKQKLGKEIVRLqkDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELK 2010
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGKVNLMA--IEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1492-1725 1.08e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1492 SKEAYEKDEQINLLKEELDQQNKRFDCLKGE---MEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLnev 1568
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEekaLLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL--- 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1569 lknyNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEhvnlSVKSKEEELKALED 1648
Cdd:COG4942     96 ----RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE----ELRADLAELAALRA 167

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462589158 1649 RLESESAAKLAELKRKAEQkiaaiKKQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSE 1725
Cdd:COG4942    168 ELEAERAELEALLAELEEE-----RAALEALKAERQKLLAR-LEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PRK01156 PRK01156
chromosome segregation protein; Provisional
 775-1371 1.08e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.51  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  775 LKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQ---SATHEQTKAYEEQLAQLQQKLLD 851
Cdd:PRK01156   188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALnelSSLEDMKNRYESEIKTAESDLSM 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  852 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQnSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKE 931
Cdd:PRK01156   268 ELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENK-KQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKS 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  932 nmilqmregQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEA--KLKKELENT 1009
Cdd:PRK01156   347 ---------RYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAikKELNEINVK 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1010 ALELSQKEKQFNAKMLEMAQaNSAGISDAVSRLETNQKEQIESlTEVHRRELNDVISIWEKKLNQQAEELQEIhEIQLQE 1089
Cdd:PRK01156   418 LQDISSKVSSLNQRIRALRE-NLDELSRNMEMLNGQSVCPVCG-TTLGEEKSNHIINHYNEKKSRLEEKIREI-EIEVKD 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1090 KEQEVAELKQkiLLFGCEKEEMNKEITwlkeegvkQDTTLNELQEQLKQKSAHVNSLAQDETKLKA--------HLEKLE 1161
Cdd:PRK01156   495 IDEKIVDLKK--RKEYLESEEINKSIN--------EYNKIESARADLEDIKIKINELKDKHDKYEEiknrykslKLEDLD 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1162 VDLNKSLKENTFLQEQLVE-LKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEF---KKLSEELAIQ 1237
Cdd:PRK01156   565 SKRTSWLNALAVISLIDIEtNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLnnkYNEIQENKIL 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1238 LDICCKKTEALLEaKTNELINISSSKtNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQAT 1317
Cdd:PRK01156   645 IEKLRGKIDNYKK-QIAEIDSIIPDL-KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDIN 722

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462589158 1318 HQLEEKenqiKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSE 1371
Cdd:PRK01156   723 ETLESM----KKIKKAIGDLKRLREAFDKSGVPAMIRKSASQAMTSLTRKYLFE 772
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1528-2168 1.18e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.34  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1528 SKMEKKESNLETELKSQTARIMELEDHItqKTIEIESLNEVLKNYNQQKDiehkelvqklqHFQELGEEKDNRVKEAEEK 1607
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQL--EALKSESQNKIELLLQQHQD-----------RIEQLISEHEVEITGLTEK 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1608 ILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESEsaakLAELKRKAEQKIAAIKKQL-LSQMEEKEEQ 1686
Cdd:pfam15921  287 ASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSE----LREAKRMYEDKIEELEKQLvLANSELTEAR 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1687 YKKGTESHLS-ELNTKLQEREREVHILEEKLkSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-- 1763
Cdd:pfam15921  363 TERDQFSQESgNLDDQLQKLLADLHKREKEL-SLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKse 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1764 -RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL-EHAEAKQ---HEDQSMIGHLQEELEEKNKKyslIVAQHVE 1838
Cdd:pfam15921  442 cQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVvEELTAKKmtlESSERTVSDLTASLQEKERA---IEATNAE 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1839 KEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLvrqkevhrvemEELTSKYEKLQALQQMDGRNKPT 1918
Cdd:pfam15921  519 ITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVI-----------EILRQQIENMTQLVGQHGRTAGA 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1919 ELLEENTEEKS----KSHLVQPKLLSNM-EAQHNDLEFKLAGAEREKQKL---GKEIVRLQKDLRMLRKEHQQELEILKK 1990
Cdd:pfam15921  588 MQVEKAQLEKEindrRLELQEFKILKDKkDAKIRELEARVSDLELEKVKLvnaGSERLRAVKDIKQERDQLLNEVKTSRN 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1991 EYDQEREEkikqeqedlelkhnstLKQLMREFNtqlaQKEQELEMTIKETINKAQEVEAELleshqEETNQLLKKIAEKD 2070
Cdd:pfam15921  668 ELNSLSED----------------YEVLKRNFR----NKSEEMETTTNKLKMQLKSAQSEL-----EQTRNTLKSMEGSD 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2071 DDLKRTAKryeeildAREEEMTAKvrdlQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEF 2150
Cdd:pfam15921  723 GHAMKVAM-------GMQKQITAK----RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGE 791

                          650
                   ....*....|....*...
gi 2462589158 2151 REQIHNLEDRLKKYEKNV 2168
Cdd:pfam15921  792 LEVLRSQERRLKEKVANM 809
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1979-2162 1.19e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1979 KEHQQELEILKKEYDQEREEKIKQEQEDLELKHNStLKQLMREFNTQLAQKEQELEmtikETINKAQEVEAELLESHQEE 2058
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEE-LEAELEELEAELAELEAELE----ELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2059 tNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEnpgndnvtimELQTQLAQKTT 2138
Cdd:COG1196    291 -YELLAELARLEQDIARLEERRRE-LEERLEELEEELAELEEELEELEEELEELEEELE----------EAEEELEEAEA 358

                          170       180
                   ....*....|....*....|....
gi 2462589158 2139 LISDSKLKEQEFREQIHNLEDRLK 2162
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELE 382
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 158-409 1.84e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.79  E-value: 1.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  158 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQS---QDKSL-RRIAELREELQMDQQAKKHLQeEFDA 233
Cdd:COG3096    839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQAnllADETLaDRLEELREELDAAQEAQAFIQ-QHGK 917

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  234 SLEEKDQYISVLQT---QVSLLKQRLRNGPMNVDVLKplPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTlETLQQRVK 310
Cdd:COG3096    918 ALAQLEPLVAVLQSdpeQFEQLQADYLQAKEQQRRLK--QQIFALSEVVQRRPHFSYEDAVGLLGENSDLN-EKLRARLE 994

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  311 RQENLLKRCKETIQSHKEQC-------TLLTSEKEALQEQLDERLQELEKIK---DLHMAEKTK-----LITQLRDAKNL 375
Cdd:COG3096    995 QAEEARREAREQLRQAQAQYsqynqvlASLKSSRDAKQQTLQELEQELEELGvqaDAEAEERARirrdeLHEELSQNRSR 1074

                          250       260       270
                   ....*....|....*....|....*....|....
gi 2462589158  376 IEQLEQDKGMVIAETKrQMHETLEMKEEEIAQLR 409
Cdd:COG3096   1075 RSQLEKQLTRCEAEMD-SLQKRLRKAERDYKQER 1107
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1508-1679 1.89e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1508 ELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiehkeLVQKL 1587
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLG-----NVRNN 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1588 QHFQELGEEKDNrvkeAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA---AKLAELKRK 1664
Cdd:COG1579     89 KEYEALQKEIES----LKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAeleAELEELEAE 164

                          170
                   ....*....|....*
gi 2462589158 1665 AEQKIAAIKKQLLSQ 1679
Cdd:COG1579    165 REELAAKIPPELLAL 179
PRK12704 PRK12704
phosphodiesterase; Provisional
 335-472 1.98e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 1.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  335 SEKEALQEQLDERLQELEKIKDLhmaeKTKLITQLRDAKNLIEQLEQdKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 414
Cdd:PRK12704    47 AKKEAEAIKKEALLEAKEEIHKL----RNEFEKELRERRNELQKLEK-RLLQKEENLDRKLELLEKREEELEKKEKELEQ 121

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462589158  415 MTTQGEELREQKEKSERAAFEELEK--ALSTAQKT----EEARRKLKAEMDEQIKTIEKTSEEE 472
Cdd:PRK12704   122 KQQELEKKEEELEELIEEQLQELERisGLTAEEAKeillEKVEEEARHEAAVLIKEIEEEAKEE 185
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
785-1209 2.10e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 2.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  785 LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERIL-----L 859
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLlqllpL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  860 TKQVAEVEAQKKDVCTELDAHKIQVQDLmQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMRE 939
Cdd:COG4717    131 YQELEALEAELAELPERLEELEERLEEL-RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLA 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  940 GQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKA-------KEMQETLKKKLLDQEAKLKKELENTALE 1012
Cdd:COG4717    210 ELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIaaallalLGLGGSLLSLILTIAGVLFLVLGLLALL 289

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1013 LSQKEKQFNAKMLEMAQANSAGISDAVSRLE-TNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKE 1091
Cdd:COG4717    290 FLLLAREKASLGKEAEELQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELE 369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1092 QEVAELKQKillFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQ--KSAHVNSLAQDETKLKAHLEKLEVDLNKSLK 1169
Cdd:COG4717    370 QEIAALLAE---AGVEDEEELRAALEQAEEYQELKEELEELEEQLEEllGELEELLEALDEEELEEELEELEEELEELEE 446

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 2462589158 1170 ENTFLQEQLVELK--MLAEEDKRKVSELTSKLKTTDEEFQSL 1209
Cdd:COG4717    447 ELEELREELAELEaeLEQLEEDGELAELLQELEELKAELREL 488
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1939-2115 2.11e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1939 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKE----YDQEREEKIK----QEQEDLELK 2010
Cdd:COG4942     57 LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlralYRLGRQPPLAlllsPEDFLDAVR 136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2011 HNSTLKQLMREFNTQLAQKEQELEM--TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDARE 2088
Cdd:COG4942    137 RLQYLKYLAPARREQAEELRADLAElaALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAE-LAAEL 215

                          170       180
                   ....*....|....*....|....*..
gi 2462589158 2089 EEMTAKVRDLQTQLEELQKKYQQKLEQ 2115
Cdd:COG4942    216 AELQQEAEELEALIARLEAEAAAAAER 242
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1070-1664 2.37e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.17  E-value: 2.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1070 KKLNQQAEELQEIHEIQLQEKEQEVAELkqkiLLFGCEKEEMNKEITWLKEEGVKQdttLNELQEQLKQKSAHVNSLAQD 1149
Cdd:pfam05483  218 KEDHEKIQHLEEEYKKEINDKEKQVSLL----LIQITEKENKMKDLTFLLEESRDK---ANQLEEKTKLQDENLKELIEK 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1150 ETKLKAHLEKLEVDLNKSLKENTFLQEQLvelkmlaEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1229
Cdd:pfam05483  291 KDHLTKELEDIKMSLQRSMSTQKALEEDL-------QIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1230 LSEELAIQLDicckKTEALLEAKTNELinisssktnailsrishcQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTL 1309
Cdd:pfam05483  364 LLRTEQQRLE----KNEDQLKIITMEL------------------QKKSSELEEMTKFKNNKEVELEELKKILAEDEKLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1310 --NISFQQATHQLEEKENQIKSMKADIESLVTEKEA-LQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEK 1386
Cdd:pfam05483  422 deKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIqLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLEN 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1387 KVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEW 1466
Cdd:pfam05483  502 KELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYE 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1467 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDC-------LKGEMEDDKSKMEKKESNLET 1539
Cdd:pfam05483  582 VLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAyeikvnkLELELASAKQKFEEIIDNYQK 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1540 ELKSQTARIMELEDHITQKTIEIESLNEVLKNYN---QQKDIEHKELVQKLQH-FQELGEEKDNRVKEAEEKiltlENQV 1615
Cdd:pfam05483  662 EIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDkrcQHKIAEMVALMEKHKHqYDKIIEERDSELGLYKNK----EQEQ 737

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 2462589158 1616 YSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRK 1664
Cdd:pfam05483  738 SSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 300-503 2.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  300 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKD----LHMAEKTKLITQLRDAKNL 375
Cdd:COG4942     55 KQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRalyrLGRQPPLALLLSPEDFLDA 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  376 IEQLEQDKGmvIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERaafeELEKALSTAQKTEEARRKLK 455
Cdd:COG4942    135 VRRLQYLKY--LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA----ALEALKAERQKLLARLEKEL 208

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2462589158  456 AEMDEQIKTIEKtseeERISLQQELSRVKQEVVDVMKKSSEEQIAKLQ 503
Cdd:COG4942    209 AELAAELAELQQ----EAEELEALIARLEAEAAAAAERTPAAGFAALK 252
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 161-553 3.00e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 3.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  161 IQRLRRMERSLSSY-RGKYSELVTAYQMLQREKKKLQGILSQ--SQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEE 237
Cdd:pfam15921  428 VQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTAQleSTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQE 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  238 KDQYISVLQTQVSLLKQRlrngpmnVDV-LKPLPQLEPQAEVFtkeENPESDGEPV-VEDGTSVKTLETLQQRVKRQENL 315
Cdd:pfam15921  508 KERAIEATNAEITKLRSR-------VDLkLQELQHLKNEGDHL---RNVQTECEALkLQMAEKDKVIEILRQQIENMTQL 577

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  316 L---KRCKETIQSHKEQCT-------LLTSEKEALQEQLDERLQELE-KIKDLHMaEKTKLITQLRDAKNLIEQLEQDKG 384
Cdd:pfam15921  578 VgqhGRTAGAMQVEKAQLEkeindrrLELQEFKILKDKKDAKIRELEaRVSDLEL-EKVKLVNAGSERLRAVKDIKQERD 656

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  385 MVIAETKRQMHETLEMKEE-EIAQ--LRSRIKQMTTQGEELREQKeKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 461
Cdd:pfam15921  657 QLLNEVKTSRNELNSLSEDyEVLKrnFRNKSEEMETTTNKLKMQL-KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQ 735

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  462 IktiekTSEEERI-SLQQELSRVKQEVVDVMKKS---SEEQIAKLQKLH----EKELARKEQELTKKLQTREREFQEQMK 533
Cdd:pfam15921  736 I-----TAKRGQIdALQSKIQFLEEAMTNANKEKhflKEEKNKLSQELStvatEKNKMAGELEVLRSQERRLKEKVANME 810

                          410       420
                   ....*....|....*....|...
gi 2462589158  534 VALEKSQSEYLK---ISQEKEQQ 553
Cdd:pfam15921  811 VALDKASLQFAEcqdIIQRQEQE 833
PRK12704 PRK12704
phosphodiesterase; Provisional
 924-1092 3.54e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 3.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  924 KQILVEKENMILQMREGQKKEIEILTQK--LSAKEDsIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEaK 1001
Cdd:PRK12704    30 EAKIKEAEEEAKRILEEAKKEAEAIKKEalLEAKEE-IHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLE-K 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1002 LKKELENTALELSQKEKQFNAKMLEMAQAnsagISDAVSRLetnqkEQIESLTEVHRRELndVISIWEKKLNQQAEELqe 1081
Cdd:PRK12704   108 REEELEKKEKELEQKQQELEKKEEELEEL----IEEQLQEL-----ERISGLTAEEAKEI--LLEKVEEEARHEAAVL-- 174

                          170
                   ....*....|.
gi 2462589158 1082 IHEIQLQEKEQ 1092
Cdd:PRK12704   175 IKEIEEEAKEE 185
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 341-900 3.62e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 3.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  341 QEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIA------ETKRQMHETLEMKEEEIAQLRSRIKQ 414
Cdd:pfam01576   21 QQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAArkqeleEILHELESRLEEEEERSQQLQNEKKK 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  415 MTTQGEELREQKEKSERAafeelEKALSTAQKTEEARRKlkaEMDEQIKTIEktseEERISLQQELSRVKQEVVDVMKKS 494
Cdd:pfam01576  101 MQQHIQDLEEQLDEEEAA-----RQKLQLEKVTTEAKIK---KLEEDILLLE----DQNSKLSKERKLLEERISEFTSNL 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  495 SEEQ-----IAKLQKLHEKELARKEQELTKKLQTRERefQEQMKVALEKSQSEYlkisqekeQQESLALEELELQKKAIL 569
Cdd:pfam01576  169 AEEEekaksLSKLKNKHEAMISDLEERLKKEEKGRQE--LEKAKRKLEGESTDL--------QEQIAELQAQIAELRAQL 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  570 TESENKLRDLQQEAETYRTRilelESSLEKSLQENKNQSKDLAVHLEAEKNKHNKeitvmVEKHKTELEslkHQQDALWT 649
Cdd:pfam01576  239 AKKEEELQAALARLEEETAQ----KNNALKKIRELEAQISELQEDLESERAARNK-----AEKQRRDLG---EELEALKT 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  650 EKLQVLKQQyqTEMEKLREKCEQEKETL---LKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEE 726
Cdd:pfam01576  307 ELEDTLDTT--AAQQELRSKREQEVTELkkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  727 ELSVLKDQTDKMKQeleAKMDEQknHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLlkerdkhlkehQAHVENLEAD 806
Cdd:pfam01576  385 ENAELQAELRTLQQ---AKQDSE--HKRKKLEGQLQELQARLSESERQRAELAEKLSKL-----------QSELESVSSL 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  807 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQD 886
Cdd:pfam01576  449 LNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSD 528

                          570
                   ....*....|....
gi 2462589158  887 LMQQLEKQNSEMEQ 900
Cdd:pfam01576  529 MKKKLEEDAGTLEA 542
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1531-1709 4.06e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1531 EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIE--HKELVQKLQHFQELgEEKDNRVKEAEEKI 1608
Cdd:COG4913    616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAsaEREIAELEAELERL-DASSDDLAALEEQL 694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1609 LTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKqllsqmEEKEEQYK 1688
Cdd:COG4913    695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG------DAVERELR 768

                          170       180
                   ....*....|....*....|.
gi 2462589158 1689 KGTESHLSELNTKLQEREREV 1709
Cdd:COG4913    769 ENLEERIDALRARLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1943-2112 4.09e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1943 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRK-------------------EHQQELEILKKEYDQERE-----E 1998
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQErrealqrlaeyswdeidvaSAEREIAELEAELERLDAssddlA 688

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1999 KIKQEQEDLELKHNsTLKQLMREFNTQLAQKEQELEmTIKETINKAQEVEAELLESHQEETNQLL-KKIAEKDDDlkRTA 2077
Cdd:COG4913    689 ALEEQLEELEAELE-ELEEELDELKGEIGRLEKELE-QAEEELDELQDRLEAAEDLARLELRALLeERFAAALGD--AVE 764

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2462589158 2078 KRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQK 2112
Cdd:COG4913    765 RELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
46 PHA02562
endonuclease subunit; Provisional
 1499-1712 4.26e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 4.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1499 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQK-D 1577
Cdd:PHA02562   187 DMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAaK 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1578 IEHK-ELVQKLQHFQELGEE---KDNRVKEAEEKIltlenqvysmkAELETKKKELEHVNLSVKSKEEELKALEDRLeSE 1653
Cdd:PHA02562   267 IKSKiEQFQKVIKMYEKGGVcptCTQQISEGPDRI-----------TKIKDKLKELQHSLEKLDTAIDELEEIMDEF-NE 334

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462589158 1654 SAAKLAELKRKAEQKIAAIK------KQLLSQMEEKEEQYK------KGTESHLSELNTKLQEREREVHIL 1712
Cdd:PHA02562   335 QSKKLLELKNKISTNKQSLItlvdkaKKVKAAIEELQAEFVdnaeelAKLQDELDKIVKTKSELVKEKYHR 405
PRK09039 PRK09039
peptidoglycan -binding protein;
355-519 4.33e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.88  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  355 KDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAetkrQMHETLEMKEEEiaqlRSRIKQMTTQGEELREQKEKseRAAf 434
Cdd:PRK09039    51 KDSALDRLNSQIAELADLLSLERQGNQDLQDSVA----NLRASLSAAEAE----RSRLQALLAELAGAGAAAEG--RAG- 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  435 eELEKALSTAQKT-EEARRKLkAEMDEQIKtiektseeeriSLQQELSRVkQEVVDVMKKSSEEQIAKLQKLHEK---EL 510
Cdd:PRK09039   120 -ELAQELDSEKQVsARALAQV-ELLNQQIA-----------ALRRQLAAL-EAALDASEKRDRESQAKIADLGRRlnvAL 185


                   ....*....
gi 2462589158  511 ARKEQELTK 519
Cdd:PRK09039   186 AQRVQELNR 194
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 614-1686 4.59e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 4.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  614 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEK------LQVLKQQYQTEMEKLREKCEQEKETL--LKDKEIIF 685
Cdd:pfam01576   50 QAETELCAEAEEMRARLAARKQELEEILHELESRLEEEeersqqLQNEKKKMQQHIQDLEEQLDEEEAARqkLQLEKVTT 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  686 QAHIEEMNEKTLEKLDvkqteleslssELSEVLKARHKLEEELSvlkDQTDKMKQELEAKMDEQKNHHQQQvdSIIKEHE 765
Cdd:pfam01576  130 EAKIKKLEEDILLLED-----------QNSKLSKERKLLEERIS---EFTSNLAEEEEKAKSLSKLKNKHE--AMISDLE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  766 VSIQRTEKALKDQIN---QLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDvfqSYQSATHEQTKAYEEQL 842
Cdd:pfam01576  194 ERLKKEEKGRQELEKakrKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLE---EETAQKNNALKKIRELE 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  843 AQLQQKLLDLETERILLTKqvaeVEAQKKDVCTELDAHKIQVQD----------LMQQLEKQNSEMEQKVKSLTQVYESK 912
Cdd:pfam01576  271 AQISELQEDLESERAARNK----AEKQRRDLGEELEALKTELEDtldttaaqqeLRSKREQEVTELKKALEEETRSHEAQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  913 LEDGNKEQEQTKQILVEKENMILQMR---EGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEmQE 989
Cdd:pfam01576  347 LQEMRQKHTQALEELTEQLEQAKRNKanlEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSE-SE 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  990 TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAgISDAVSRLETNQKEQIESLTEVhrRELNDVISIWE 1069
Cdd:pfam01576  426 RQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQ-LQDTQELLQEETRQKLNLSTRL--RQLEDERNSLQ 502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1070 KKLNQQAEELQEIhEIQLQEKEQEVAELKQKIllfgcekEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQD 1149
Cdd:pfam01576  503 EQLEEEEEAKRNV-ERQLSTLQAQLSDMKKKL-------EEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKT 574

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1150 ETKLKAHLEKLEVDLNKslkentflQEQLVelkmlaeedkrkvseltsklkttdeefqslkSSHEKSNKSLEdkslefKK 1229
Cdd:pfam01576  575 KNRLQQELDDLLVDLDH--------QRQLV-------------------------------SNLEKKQKKFD------QM 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1230 LSEELAIQLDICCKKTEALLEAKTNELINISSSKtnailsrishcqhrttkvkeALLIKTCTVSELEAQLRQLTEEQNTL 1309
Cdd:pfam01576  610 LAEEKAISARYAEERDRAEAEAREKETRALSLAR--------------------ALEEALEAKEELERTNKQLRAEMEDL 669

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1310 NISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAvtlmkeELKEKKVE 1389
Cdd:pfam01576  670 VSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQA------RDEQGEEK 743

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1390 ISSLSKQLTDLNVQLQNSislSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1469
Cdd:pfam01576  744 RRQLVKQVRELEAELEDE---RKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARAS 820

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1470 AQSRFTQHQNTVKELQ------IQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKS 1543
Cdd:pfam01576  821 RDEILAQSKESEKKLKnleaelLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEE 900

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1544 QTARIMELEDHITQKTIEIESLNEVL----------KNYNQQKDIEHKELVQKLQHFQELGEEKdnrvkeAEEKILTLEN 1613
Cdd:pfam01576  901 EQSNTELLNDRLRKSTLQVEQLTTELaaerstsqksESARQQLERQNKELKAKLQEMEGTVKSK------FKSSIAALEA 974

                         1050      1060      1070      1080      1090      1100      1110
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462589158 1614 QVYSMKAELETKKKELEHVNLSVKSKEEELKalEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1686
Cdd:pfam01576  975 KIAQLEEQLEQESRERQAANKLVRRTEKKLK--EVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEE 1045
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 333-604 4.63e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 42.34  E-value: 4.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  333 LTSEK-EALQEQLDERLQELEKIKdlhmaeKTKLITQ-LRDAKNLIEQLEQDKGMViaETKRQMHETLEMKEEEIaQLRS 410
Cdd:PTZ00108  1099 LTKEKvEKLNAELEKKEKELEKLK------NTTPKDMwLEDLDKFEEALEEQEEVE--EKEIAKEQRLKSKTKGK-ASKL 1169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  411 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEqiKTIEKTSEEERISLQQELSRVKQEVVDV 490
Cdd:PTZ00108  1170 RKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSN--SSGSDQEDDEEQKTKPKKSSVKRLKSKK 1247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  491 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQ------SEYLKISQEKEQQESLALEELELQ 564
Cdd:PTZ00108  1248 NNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNggskpsSPTKKKVKKRLEGSLAALKKKKKS 1327

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2462589158  565 KKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQEN 604
Cdd:PTZ00108  1328 EKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSED 1367
PRK12704 PRK12704
phosphodiesterase; Provisional
 370-509 4.78e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  370 RDAKNLIEQLEQDKGMVIAETKRQMHEtleMKEEEIAQLRSRIKQMTTQGE-ELRE------QKEKSERAAFEELEKALS 442
Cdd:PRK12704    27 KIAEAKIKEAEEEAKRILEEAKKEAEA---IKKEALLEAKEEIHKLRNEFEkELRErrnelqKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462589158  443 TAQKTEEARRKLKAEMDEQIKTIEKTSEE-ERISLQQ--ELSRV--------KQEVVDVMKKSSEEQIAKLQKLHEKE 509
Cdd:PRK12704   104 LLEKREEELEKKEKELEQKQQELEKKEEElEELIEEQlqELERIsgltaeeaKEILLEKVEEEARHEAAVLIKEIEEE 181
PRK12704 PRK12704
phosphodiesterase; Provisional
 1654-1830 4.82e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1654 SAAKLAELKRKAEQKIA-------AIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKsvesSQSET 1726
Cdd:PRK12704    29 AEAKIKEAEEEAKRILEeakkeaeAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLD----RKLEL 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1727 LivprSAKNVAAYTEQEEADSQgcvQKTYEEKISVLQRNLTEKEKLLQRV-GQEKEETvsshfemrcqyqeRLIKLEHAE 1805
Cdd:PRK12704   105 L----EKREEELEKKEKELEQK---QQELEKKEEELEELIEEQLQELERIsGLTAEEA-------------KEILLEKVE 164

                          170       180
                   ....*....|....*....|....*.
gi 2462589158 1806 AK-QHEDQSMIGHLQEELEEKNKKYS 1830
Cdd:PRK12704   165 EEaRHEAAVLIKEIEEEAKEEADKKA 190
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
139-617 4.84e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 42.33  E-value: 4.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  139 SDMDSEAEDLVGNS--DSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGilsqsqdkslrRIAELREE 216
Cdd:PRK02224   289 EELEEERDDLLAEAglDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLRE-----------DADDLEER 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  217 LQMDQQAKKHLQEEFDAS---LEEKDQYISVLQTQVSLLKQRLRNGPMNVDvlkplpqlepqaEVFTKEENPESDGEPVV 293
Cdd:PRK02224   358 AEELREEAAELESELEEAreaVEDRREEIEELEEEIEELRERFGDAPVDLG------------NAEDFLEELREERDELR 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  294 EDGTSVK-TLETLQQRVKRQENLLK--RCKETIQSHKEQ---CTLltSEKEALQEQLDERLQELEkikdLHMAEKTKLIT 367
Cdd:PRK02224   426 EREAELEaTLRTARERVEEAEALLEagKCPECGQPVEGSphvETI--EEDRERVEELEAELEDLE----EEVEEVEERLE 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  368 QLRDAKNLIEQLEQDKgmviaetkrqmhETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT 447
Cdd:PRK02224   500 RAEDLVEAEDRIERLE------------ERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  448 EEARRKLK------AEMDEQIKTIEK--TSEEERISLQQELSRVKQevvdvmkksseeqiaKLQKLHEKELARKEQELTK 519
Cdd:PRK02224   568 EEAREEVAelnsklAELKERIESLERirTLLAAIADAEDEIERLRE---------------KREALAELNDERRERLAEK 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  520 KLQTREREfqeqmkvalEKSQSEYLKISQEKEQQEslaleelelqkKAILTESENKLRDLQQEAETYRTRILELESSLEk 599
Cdd:PRK02224   633 RERKRELE---------AEFDEARIEEAREDKERA-----------EEYLEQVEEKLDELREERDDLQAEIGAVENELE- 691

                          490
                   ....*....|....*...
gi 2462589158  600 SLQENKNQSKDLAVHLEA 617
Cdd:PRK02224   692 ELEELRERREALENRVEA 709
HlpA COG2825
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...
 1957-2044 4.89e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442073 [Multi-domain]  Cd Length: 171  Bit Score: 40.20  E-value: 4.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1957 EREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDlelkhnstLKQLMREFNTQLAQKEQELEMT 2036
Cdd:COG2825     49 EKEFKKRQAELQKLEKELQALQEKLQKEAATLSEEERQKKERELQKKQQE--------LQRKQQEAQQDLQKRQQELLQP 120


                   ....*...
gi 2462589158 2037 IKETINKA 2044
Cdd:COG2825    121 ILEKIQKA 128
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 788-1221 5.19e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.12  E-value: 5.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  788 ERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAThEQTKAYEeqlaqlqQKLLDLETERILLTKQVAEVE 867
Cdd:pfam10174  182 ERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDP-AKTKALQ-------TVIEMKDTKISSLERNIRDLE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  868 AQKKDVCTELDAHKIQVQDLMQQLEKQNSE---MEQKVKSLTQvyesklEDGNKEQEQtkQILVEKENMILQMREGQKKE 944
Cdd:pfam10174  254 DEVQMLKTNGLLHTEDREEEIKQMEVYKSHskfMKNKIDQLKQ------ELSKKESEL--LALQTKLETLTNQNSDCKQH 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  945 IEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQET-------------LKKKLLDQEAK---LKKELEN 1008
Cdd:pfam10174  326 IEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLteekstlageirdLKDMLDVKERKinvLQKKIEN 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1009 TALELSQKEKQFnakmlemaqansAGISDAVSRLETNQKEQIESLTEvhrreLNDVISIWEKKLnqqaEELQEIHEIQLQ 1088
Cdd:pfam10174  406 LQEQLRDKDKQL------------AGLKERVKSLQTDSSNTDTALTT-----LEEALSEKERII----ERLKEQREREDR 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1089 EKEQEVAELKQkillfgcEKEEMNKEITWLKEEGVKQDTTLNELQEqlkqksaHVNSLAQDETKLKAHLEKLEVDLNKSL 1168
Cdd:pfam10174  465 ERLEELESLKK-------ENKDLKEKVSALQPELTEKESSLIDLKE-------HASSLASSGLKKDSKLKSLEIAVEQKK 530

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462589158 1169 KENTFLQEQLVELKMlAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1221
Cdd:pfam10174  531 EECSKLENQLKKAHN-AEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVE 582
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1637-1911 5.48e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 5.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1637 KSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKL 1716
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEE 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1717 KSVESS---QSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYeekisvlQRNLTEKEKLLQRVGQEKEEtvSSHFEMRCQ 1793
Cdd:pfam17380  370 IAMEISrmrELERLQMERQQKNERVRQELEAARKVKILEEER-------QRKIQQQKVEMEQIRAEQEE--ARQREVRRL 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1794 YQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNniQAKQNLENVFDDVQKTLQEKELTCQIL 1873
Cdd:pfam17380  441 EEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEE--QRRKILEKELEERKQAMIEEERKRKLL 518

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2462589158 1874 EQKIKELDSCLVRQKEVHRVEMEELTSK--YEKLQALQQM 1911
Cdd:pfam17380  519 EKEMEERQKAIYEEERRREAEEERRKQQemEERRRIQEQM 558
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1983-2126 5.54e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 5.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1983 QELEILKKEYDQEREE--KIKQEQEDLELKhnstLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEEtn 2060
Cdd:PRK00409   523 ASLEELERELEQKAEEaeALLKEAEKLKEE----LEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQL-- 596

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2061 QLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDlQTQLEELQK----KYQQKLEQEENPGNDNVTI 2126
Cdd:PRK00409   597 QKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEK-QEELKVGDEvkylSLGQKGEVLSIPDDKEAIV 665
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 158-741 5.63e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 5.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  158 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLR---RIAELREELQMDQQAKKHLQ---EEF 231
Cdd:TIGR02169  367 EDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRlseELADLNAAIAGIEAKINELEeekEDK 446

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  232 DASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVL--------KPLPQLEPQAEVFTKEENPESDGEPVVEDGTS----- 298
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVekelsklqRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgt 526

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  299 -----------VKTLET-----LQQRVKRQENLLKRCKETIQSHK-EQCTLLTSEKEALQEQLDERLQELEKIKDLhmae 361
Cdd:TIGR02169  527 vaqlgsvgeryATAIEVaagnrLNNVVVEDDAVAKEAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGVIGFA---- 602

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  362 kTKLITQLRDAKNLIEQLEQDKGMV--IAETKRQMHE----TLE-------------------------MKEEEIAQLRS 410
Cdd:TIGR02169  603 -VDLVEFDPKYEPAFKYVFGDTLVVedIEAARRLMGKyrmvTLEgelfeksgamtggsraprggilfsrSEPAELQRLRE 681

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  411 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKA--EMDEQIKTIEKTSEEERISLQQELSRVKQEVV 488
Cdd:TIGR02169  682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQleQEEEKLKERLEELEEDLSSLEQEIENVKSELK 761

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  489 DVMKKSS--EEQIAKLQKLHEKELARKEQELTKKLQtREREFQEQMKVALEKSQSEyLKISQEKEQQESLALEELELQKK 566
Cdd:TIGR02169  762 ELEARIEelEEDLHKLEEALNDLEARLSHSRIPEIQ-AELSKLEEEVSRIEARLRE-IEQKLNRLTLEKEYLEKEIQELQ 839

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  567 AILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvHLEAEKNKHNKEITVM---VEKHKTELESLKHQ 643
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG-DLKKERDELEAQLRELerkIEELEAQIEKKRKR 918

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  644 QDALwTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKeiiFQAHIEEMNE--KTLEKLDVKQTELESLSSELSEVLKAR 721
Cdd:TIGR02169  919 LSEL-KAKLEALEEELSEIEDPKGEDEEIPEEELSLED---VQAELQRVEEeiRALEPVNMLAIQEYEEVLKRLDELKEK 994

                          650       660
                   ....*....|....*....|.
gi 2462589158  722 H-KLEEELSVLKDQTDKMKQE 741
Cdd:TIGR02169  995 RaKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 495-873 5.68e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 5.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  495 SEEQIAKLQKLHEK--ELARKEQELTKKLQTREREFQEqMKVALEKSQSEYLKISQEKEQqeslaLEELELQKKAILTES 572
Cdd:TIGR02169  669 SRSEPAELQRLRERleGLKRELSSLQSELRRIENRLDE-LSQELSDASRKIGEIEKEIEQ-----LEQEEEKLKERLEEL 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  573 ENKLRDLQQEAETYRTRILELESSLEKsLQENKNQSKDLAVHLEAEKNKHN-KEITVMVEKHKTELESLKHQQDAL--WT 649
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELEARIEE-LEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIeqKL 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  650 EKLQVLKQQYQTEMEKLrekceQEKETLLKDKEIIFQAHIEEMN---EKTLEKLDVKQTELESLSSELSEVLKARHKLEE 726
Cdd:TIGR02169  822 NRLTLEKEYLEKEIQEL-----QEQRIDLKEQIKSIEKEIENLNgkkEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  727 ELSVLKDQtdkmKQELEAKMDEQKNHHQQQvdsiikehevsiQRTEKALKDQINQLELLLKErDKHLKEHQAHVENLEAD 806
Cdd:TIGR02169  897 QLRELERK----IEELEAQIEKKRKRLSEL------------KAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAE 959

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462589158  807 IKRSEGELQQasakldvFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDV 873
Cdd:TIGR02169  960 LQRVEEEIRA-------LEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1940-2116 6.22e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 6.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1940 SNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH---------QQELEILKkEYDQEREEkIKQEQEDLELK 2010
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglvdlseeaKLLLQQLS-ELESQLAE-ARAELAEAEAR 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2011 HNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQ---LLKKIAEKDDDLKRTAKRYEEILDAR 2087
Cdd:COG3206    242 LAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDviaLRAQIAALRAQLQQEAQRILASLEAE 321

                          170       180       190
                   ....*....|....*....|....*....|.
gi 2462589158 2088 EEEMTAKVRDLQTQLEELQKKYQQ--KLEQE 2116
Cdd:COG3206    322 LEALQAREASLQAQLAQLEARLAElpELEAE 352
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 329-1099 6.68e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.88  E-value: 6.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  329 QCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLiTQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQL 408
Cdd:TIGR00618  153 EFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKK-KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  409 RSRIKQMTTQGEELREQKEKSERAafEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQElsrvkqevv 488
Cdd:TIGR00618  232 REALQQTQQSHAYLTQKREAQEEQ--LKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIK--------- 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  489 dvmkksSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVAlEKSQSEYLKISQEKEQQESLALEELELQKKAI 568
Cdd:TIGR00618  301 ------AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIE-EQRRLLQTLHSQEIHIRDAHEVATSIREISCQ 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  569 LTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLkHQQDALW 648
Cdd:TIGR00618  374 QHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAA-AITCTAQ 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  649 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNE-KTLEKLDVKQTELESLSSELSEVLKARHKLEEE 727
Cdd:TIGR00618  453 CEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLElQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQR 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  728 LSVLKDQTDKMKQELEAKMDEQKNHHQqqvdsIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 807
Cdd:TIGR00618  533 GEQTYAQLETSEEDVYHQLTSERKQRA-----SLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  808 KRSEGELQQASAKLDVFQS-YQSATHEQTKAYEEQLAqlqqklldleteriLLTKQVAEVEAQKKDVCTELDAHKIQVQD 886
Cdd:TIGR00618  608 DMLACEQHALLRKLQPEQDlQDVRLHLQQCSQELALK--------------LTALHALQLTLTQERVREHALSIRVLPKE 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  887 LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTkqilvEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEY 966
Cdd:TIGR00618  674 LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELE-----THIEEYDREFNEIENASSSLGSDLAAREDALNQSLKEL 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  967 ETKFKNQEKKMEKVKQKAKEmQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQ 1046
Cdd:TIGR00618  749 MHQARTVLKARTEAHFNNNE-EVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLV 827

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462589158 1047 KEQIESLTEVHRR-----ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQ 1099
Cdd:TIGR00618  828 QEEEQFLSRLEEKsatlgEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIK 885
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 273-505 6.74e-03

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 41.57  E-value: 6.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  273 EPQAEVFTKEENPESDGEPVVEDGTS-VKTLETLQQRVKRQEnLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERlqel 351
Cdd:pfam10168  477 PPSPPLLCSKEDVTVDEPLRGLQEDSfEDHIKSILQRSVSNP-ILSADKLSSPSPQECLQLLSRATQVFREEYLKK---- 551

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  352 ekiKDLHMAEKTKLITQLRDAKnliEQLEQDKGMVIAETK--RQMHETLEMKEEEIAQ----LRSRIKQMTTQGEELREQ 425
Cdd:pfam10168  552 ---HDLAREEIQKRVKLLKLQK---EQQLQELQSLEEERKslSERAEKLAEKYEEIKDkqekLMRRCKKVLQRLNSQLPV 625

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  426 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER---ISLQQELSRVKQEVVDVMKKSSEEQIAKL 502
Cdd:pfam10168  626 LSDAEREMKKELETINEQLKHLANAIKQAKKKMNYQRYQIAKSQSIRKkssLSLSEKQRKTIKEILKQLGSEIDELIKQV 705


                   ...
gi 2462589158  503 QKL 505
Cdd:pfam10168  706 KDI 708
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1592-1720 6.97e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 6.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1592 ELGEEKDnrvkEAEEKILTLENQvysmKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAA 1671
Cdd:PRK00409   510 LIGEDKE----KLNELIASLEEL----ERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKE 581

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462589158 1672 IKK---QLLSQMEEKEEQYKKGTESH-----LSELNTKLQEREREVHILEEKLKSVE 1720
Cdd:PRK00409   582 AKKeadEIIKELRQLQKGGYASVKAHelieaRKRLNKANEKKEKKKKKQKEKQEELK 638
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 863-981 6.97e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 6.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  863 VAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKE-QEQTKQILVEKENMILQMREGQ 941
Cdd:PRK00409   522 IASLEELER----ELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEaQQAIKEAKKEADEIIKELRQLQ 597

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 2462589158  942 KKEI-EILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVK 981
Cdd:PRK00409   598 KGGYaSVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELK 638
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 511-1346 7.13e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  511 ARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKIsqEKEQQESLALEELELQKKAiLTESENKLRDLQQEAETYRTRI 590
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRR--EREKAERYQALLKEKREYE-GYELLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  591 LELESSLEKS---LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALwtEKLQVLKQQYQTEMEKLR 667
Cdd:TIGR02169  247 ASLEEELEKLteeISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--ERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  668 EKCEQEKETLLKDKEIIfqahieemnEKTLEKLDVKqteleslsselsevlkaRHKLEEELSVLKDQTDKMKQELEAKMD 747
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEEL---------EREIEEERKR-----------------RDKLTEEYAELKEELEDLRAELEEVDK 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  748 EQKNHHQQQVDSIIKEHEVSIQRTEkaLKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 827
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKREINE--LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  828 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVqdlmQQLEKQNSEMEQKVKSLTQ 907
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE----EVLKASIQGVHGTVAQLGS 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  908 V---YESKLE--DGNKEQE---QTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNE---------EYETKF 970
Cdd:TIGR02169  533 VgerYATAIEvaAGNRLNNvvvEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGvigfavdlvEFDPKY 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  971 KNQEKK-------MEKVKQKAKEMQE----TLKKKLLDQE------AKLKKELENTALELSQKEKQFNAKMLEMaQANSA 1033
Cdd:TIGR02169  613 EPAFKYvfgdtlvVEDIEAARRLMGKyrmvTLEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGL-KRELS 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1034 GISDAVSRLETNQKEQIESLTEVHR--RELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQkillfgcEKEEM 1111
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSDASRkiGEIEKEIEQLEQEEEKLKERLEEL-EEDLSSLEQEIENVKS-------ELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1112 NKEITWLKEEGVKQDTTLNEL-----QEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAE 1186
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1187 EDKRKVSELTSK---LKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEA--KTNELINISS 1261
Cdd:TIGR02169  844 DLKEQIKSIEKEienLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQieKKRKRLSELK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1262 SKTNAILSRISHCQhrtTKVKEALLIKTCTVSE--LEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVT 1339
Cdd:TIGR02169  924 AKLEALEEELSEIE---DPKGEDEEIPEEELSLedVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEE 1000


                   ....*..
gi 2462589158 1340 EKEALQK 1346
Cdd:TIGR02169 1001 ERKAILE 1007
PRK12704 PRK12704
phosphodiesterase; Provisional
 1960-2091 7.26e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 7.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1960 KQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNtQLAQKEQELEMtike 2039
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQKEENLDR---- 100

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462589158 2040 tinkaqevEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM 2091
Cdd:PRK12704   101 --------KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1292-1473 7.74e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 7.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1292 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK----- 1366
Cdd:COG3883     32 LEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDvllgs 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1367 KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQnsiSLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLS 1446
Cdd:COG3883    112 ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKA---ELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLS 188

                          170       180
                   ....*....|....*....|....*..
gi 2462589158 1447 KEKISALEQVDDWSNKFSEWKKKAQSR 1473
Cdd:COG3883    189 AEEAAAEAQLAELEAELAAAEAAAAAA 215
COG5022 COG5022
Myosin heavy chain [General function prediction only];
311-813 7.75e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.60  E-value: 7.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  311 RQENLLKRCKETIQSHKEQCTLltsEKEALQEQLDERLQELEK-IKDLHMAEKTklITQLrdaKNLIEQLEQDKGMVIAE 389
Cdd:COG5022    843 KAEVLIQKFGRSLKAKKRFSLL---KKETIYLQSAQRVELAERqLQELKIDVKS--ISSL---KLVNLELESEIIELKKS 914

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  390 TKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT-EEARRKLKAEMDEQIKTIEKT 468
Cdd:COG5022    915 LSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEyEDLLKKSTILVREGNKANSEL 994

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  469 S---------EEERISLQQELSRVKQEVVDVMKKSSEEQI--------------AKLQKLHEKELARKEQELTKKLQTRE 525
Cdd:COG5022    995 KnfkkelaelSKQYGALQESTKQLKELPVEVAELQSASKIissestelsilkplQKLKGLLLLENNQLQARYKALKLRRE 1074

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  526 REFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK 605
Cdd:COG5022   1075 NSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQL 1154

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  606 ---------------------NQSKDLAVHLEAEKNKhNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME 664
Cdd:COG5022   1155 eldglfweanlealpspppfaALSEKRLYQSALYDEK-SKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVP 1233

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  665 KLREKCEQEKEtllkDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMK-QELE 743
Cdd:COG5022   1234 TEYSTSLKGFN----NLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKaSSLR 1309

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  744 AKMDEQKNHHQQQVDSIIKEHEVS-----------IQRTEKALKDQINQLELLLKERDKHLkehQAHVENLEADIKRSEG 812
Cdd:COG5022   1310 WKSATEVNYNSEELDDWCREFEISdvdeeleeliqAVKVLQLLKDDLNKLDELLDACYSLN---PAEIQNLKSRYDPADK 1386


                   .
gi 2462589158  813 E 813
Cdd:COG5022   1387 E 1387
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 440-618 8.35e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 8.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  440 ALSTAQKTEEARRKLKAEMDEQIKTIEKTsEEERISLQQELSRVKQEVVDVMKK--SSEEQIAKLQKlHEKELARKEQEL 517
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAAL-KKEEKALLKQLAALERRIAALARRirALEQELAALEA-ELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  518 TKKLQTREREFQEQMKVALEKSQSEYLKI---------------------------------SQEKEQQESLALEELELQ 564
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPLALllspedfldavrrlqylkylaparreqaeelraDLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158  565 KKAILTESENKLRDLQQEAETYRTRILELESSLEK------SLQENKNQSKDLAVHLEAE 618
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAElaaelaELQQEAEELEALIARLEAE 235
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1939-2172 9.66e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.21  E-value: 9.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1939 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKE---------HQQELEILKKEYDQEREEKIKQEQEDLEL 2009
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKikdlgeeeqLRVKEKIGELEAEIASLERSIAEKERELE 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2010 KHNSTLKQLMREFNTQLAQKEqELEMTIKETINKAQEVEAELLEShQEETNQLLKKIAEKDDDLKRTakrYEEILDARE- 2088
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIE-ELEREIEEERKRRDKLTEEYAEL-KEELEDLRAELEEVDKEFAET---RDELKDYREk 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 2089 -EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDsKLKEQEfrEQIHNLEDRLKKYEKN 2167
Cdd:TIGR02169  394 lEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL-EIKKQE--WKLEQLAADLSKYEQE 470


                   ....*
gi 2462589158 2168 VYATT 2172
Cdd:TIGR02169  471 LYDLK 475
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1046-1578 9.77e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.04  E-value: 9.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1046 QKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELKQKILLFGCEKEEMNK----EITWLKEE 1121
Cdd:PRK01156   208 DDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSS-LEDMKNRYESEIKTAESDLSMELEKNNYykelEERHMKII 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1122 GVKQDTTLNELQEQLKQKSaHVNSLAQDETKLKAHLEKLEvDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELtsklKT 1201
Cdd:PRK01156   287 NDPVYKNRNYINDYFKYKN-DIENKKQILSNIDAEINKYH-AIIKKLSVLQKDYNDYIKKKSRYDDLNNQILEL----EG 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1202 TDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLE--AKTNELINISSSKTNAILSRISHCQHRTT 1279
Cdd:PRK01156   361 YEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKelNEINVKLQDISSKVSSLNQRIRALRENLD 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1280 KVKEALLI----KTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAA 1355
Cdd:PRK01156   441 ELSRNMEMlngqSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINE 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1356 SEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLD-- 1433
Cdd:PRK01156   521 YNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDle 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462589158 1434 -QVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQhqntVKELQIQLELKSKEAYEKDEQINLLKE---EL 1509
Cdd:PRK01156   601 sRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKIL----IEKLRGKIDNYKKQIAEIDSIIPDLKEitsRI 676

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462589158 1510 DQQNKRFDCLKGEMEDDKSKMEKKESNLETELKsqtaRIMELEDHITQKTIEIESLNEVLKNYNQQKDI 1578
Cdd:PRK01156   677 NDIEDNLKKSRKALDDAKANRARLESTIEILRT----RINELSDRINDINETLESMKKIKKAIGDLKRL 741
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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