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Conserved domains on  [gi|2462601311|ref|XP_054207976|]
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coiled-coil domain-containing protein 125 isoform X15 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DR0291 super family cl34310
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 34-179 2.54e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


The actual alignment was detected with superfamily member COG1579:

Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.14  E-value: 2.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462601311  34 EELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAilgkatshtqAVLQKTMEQNRSlEKEINALQWEIEFDH 113
Cdd:COG1579    34 AELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI----------KKYEEQLGNVRN-NKEYEALQKEIESLK 102

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462601311 114 NRFKNIEESWIQKYDRLncenAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQE 179
Cdd:COG1579   103 RRISDLEDEILELMERI----EELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
 
Name Accession Description Interval E-value
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 34-179 2.54e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.14  E-value: 2.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462601311  34 EELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAilgkatshtqAVLQKTMEQNRSlEKEINALQWEIEFDH 113
Cdd:COG1579    34 AELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI----------KKYEEQLGNVRN-NKEYEALQKEIESLK 102

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462601311 114 NRFKNIEESWIQKYDRLncenAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQE 179
Cdd:COG1579   103 RRISDLEDEILELMERI----EELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
 
Name Accession Description Interval E-value
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 34-179 2.54e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.14  E-value: 2.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462601311  34 EELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAilgkatshtqAVLQKTMEQNRSlEKEINALQWEIEFDH 113
Cdd:COG1579    34 AELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI----------KKYEEQLGNVRN-NKEYEALQKEIESLK 102

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462601311 114 NRFKNIEESWIQKYDRLncenAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQE 179
Cdd:COG1579   103 RRISDLEDEILELMERI----EELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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