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Conserved domains on  [gi|2462603775|ref|XP_054209166|]
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excitatory amino acid transporter 1 isoform X3 [Homo sapiens]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
5-389 2.83e-102

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 310.12  E-value: 2.83e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775   5 DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADaFLDLIRNMFPPNLVEAcfkqfk 84
Cdd:COG1301    63 DLKKLGRIGGKTLLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------ 135
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775  85 tnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgSVNGvNALGLVVFSMCFGFVIGNMKEQGQALREFF 164
Cdd:COG1301   136 ---------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFF 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 165 DSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMeDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGG 244
Cdd:COG1301   170 ESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRA 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 245 LLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISI 324
Cdd:COG1301   248 IRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVL 327
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462603775 325 TATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEH 389
Cdd:COG1301   328 TAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
5-389 2.83e-102

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 310.12  E-value: 2.83e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775   5 DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADaFLDLIRNMFPPNLVEAcfkqfk 84
Cdd:COG1301    63 DLKKLGRIGGKTLLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------ 135
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775  85 tnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgSVNGvNALGLVVFSMCFGFVIGNMKEQGQALREFF 164
Cdd:COG1301   136 ---------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFF 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 165 DSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMeDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGG 244
Cdd:COG1301   170 ESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRA 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 245 LLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISI 324
Cdd:COG1301   248 IRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVL 327
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462603775 325 TATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEH 389
Cdd:COG1301   328 TAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
5-390 8.34e-99

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 300.59  E-value: 8.34e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775   5 DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKeNMHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQfk 84
Cdd:pfam00375  58 DGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG-- 134
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775  85 tnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgsvngvNALGLVVFSMCFGFVIGNMKEQGQALREFF 164
Cdd:pfam00375 135 --------------------------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFI 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 165 DSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEmEDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGG 244
Cdd:pfam00375 165 ESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKK 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 245 LLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISI 324
Cdd:pfam00375 243 MLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVL 322
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462603775 325 TATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHL 390
Cdd:pfam00375 323 TATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
127-379 1.15e-32

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 128.10  E-value: 1.15e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 127 VPGSVNGVNALG----LVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIvemedmGV 202
Cdd:PRK01663  137 IPTTVVGAFASGdilqVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFGAMAFTI------GK 210
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 203 IG----GQLAMYTVTVIVGLLIHAVIVLPLlyflVTRK---NPWVFIGGLLQALITALGTSSSSATLPITFKCLEeNNGV 275
Cdd:PRK01663  211 YGvgslVQLGQLIGCFYITCILFVFVVLGA----IARLtgfSIFKFIRYIKEELLIVLGTSSSESALPRMMEKME-KLGC 285
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 276 DKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LP 354
Cdd:PRK01663  286 KKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIP 365
                         250       260
                  ....*....|....*....|....*
gi 2462603775 355 TDDITLIIAVDWFLDRLRTTTNVLG 379
Cdd:PRK01663  366 VAGLALILGIDRFMSEARALTNLIG 390
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
5-389 2.83e-102

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 310.12  E-value: 2.83e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775   5 DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADaFLDLIRNMFPPNLVEAcfkqfk 84
Cdd:COG1301    63 DLKKLGRIGGKTLLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------ 135
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775  85 tnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgSVNGvNALGLVVFSMCFGFVIGNMKEQGQALREFF 164
Cdd:COG1301   136 ---------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFF 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 165 DSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMeDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGG 244
Cdd:COG1301   170 ESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRA 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 245 LLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISI 324
Cdd:COG1301   248 IRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVL 327
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462603775 325 TATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEH 389
Cdd:COG1301   328 TAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
5-390 8.34e-99

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 300.59  E-value: 8.34e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775   5 DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKeNMHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQfk 84
Cdd:pfam00375  58 DGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG-- 134
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775  85 tnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgsvngvNALGLVVFSMCFGFVIGNMKEQGQALREFF 164
Cdd:pfam00375 135 --------------------------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFI 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 165 DSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEmEDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGG 244
Cdd:pfam00375 165 ESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKK 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 245 LLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISI 324
Cdd:pfam00375 243 MLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVL 322
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462603775 325 TATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHL 390
Cdd:pfam00375 323 TATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
127-379 1.15e-32

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 128.10  E-value: 1.15e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 127 VPGSVNGVNALG----LVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIvemedmGV 202
Cdd:PRK01663  137 IPTTVVGAFASGdilqVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFGAMAFTI------GK 210
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 203 IG----GQLAMYTVTVIVGLLIHAVIVLPLlyflVTRK---NPWVFIGGLLQALITALGTSSSSATLPITFKCLEeNNGV 275
Cdd:PRK01663  211 YGvgslVQLGQLIGCFYITCILFVFVVLGA----IARLtgfSIFKFIRYIKEELLIVLGTSSSESALPRMMEKME-KLGC 285
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 276 DKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LP 354
Cdd:PRK01663  286 KKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIP 365
                         250       260
                  ....*....|....*....|....*
gi 2462603775 355 TDDITLIIAVDWFLDRLRTTTNVLG 379
Cdd:PRK01663  366 VAGLALILGIDRFMSEARALTNLIG 390
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
137-382 2.57e-30

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 121.41  E-value: 2.57e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 137 LGLVVFSMCFGFVIGNM-KEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIggQLAMYTVTVI 215
Cdd:PRK11283  161 LPIIFFSVLFGLGLSSLpATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLW--PLAKLVLLVY 238
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 216 VGLLIHAVIVLPLLYFLVtRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENnGVDKRVTRFVLPVGATINMDGT 295
Cdd:PRK11283  239 FAILFFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAY-GAPKSITSFVVPTGYSFNLDGS 316
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 296 ALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTT 375
Cdd:PRK11283  317 TLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTAL 396

                  ....*..
gi 2462603775 376 NVLGDSL 382
Cdd:PRK11283  397 NVVGNAL 403
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
135-380 4.60e-30

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 120.54  E-value: 4.60e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 135 NALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIA---GK--IVEMEDMGVIggqLAM 209
Cdd:PRK13027  149 DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPLGVLGAIAfttGKygVGSLKQLGML---VAV 225
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 210 YTVTVIVGLLIHAVIVLPLLYFLVtrknpWVFIGGLLQALITALGTSSSSATLPITFKCLEeNNGVDKRVTRFVLPVGAT 289
Cdd:PRK13027  226 FYLTCFVFVVVVLGAVMRLAGFSV-----FKLIRYLREELLIVLGTASSDAVLPQVMRKLE-HMGIKDSTVGLVIPTGYS 299
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 290 INMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LPTDDITLIIAVDWFL 368
Cdd:PRK13027  300 FNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFM 379
                         250
                  ....*....|..
gi 2462603775 369 DRLRTTTNVLGD 380
Cdd:PRK13027  380 GIARALTNLIGN 391
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
91-389 4.89e-16

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 78.55  E-value: 4.89e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775  91 SFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVP-GSVNGVNALGLVVFSMCFGFVignMKEQGQALREFFDSLNE 169
Cdd:PRK14695   15 SFIVPIEITLNSANTEIAPPDGIGQVLSNLLLKLVDSPvNALLTANYIGILSWAVIFGIA---MREASKNSKELLKTIAD 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 170 AIMRLVAVIMWYAPVGILFLIAGKIvemEDMGVigGQLAMY---TVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLL 246
Cdd:PRK14695   92 VTSKIVEWIINLAPFGILGLVFKTI---SDKGV--GSLANYgilLVLLVTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCL 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 247 Q-ALITALGTSSSSATLPITFKcLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISIT 325
Cdd:PRK14695  167 RvSGVTAFFTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTINMAGVAITINLLTLVTVNTLGIPVDFATAFVLSVV 245
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462603775 326 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFL----DRLRTTTNVLGDSLGAGIVEH 389
Cdd:PRK14695  246 AAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqDSCETALNSSTDVLFTAVAEY 313
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
132-336 1.88e-15

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 77.60  E-value: 1.88e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 132 NGVNAL------GLVVFSMCFGFVignMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIG- 204
Cdd:PRK13628  137 NPINALlnanyiGILAWAIGLGLA---LRHASDTTKNVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAETGFSALAGy 213
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 205 GQLAMytvtVIVG-LLIHAVIVLPLLYFLVTRKNPW--VFIgGLLQALITALGTSSSSATLPITFKcLEENNGVDKRVTR 281
Cdd:PRK13628  214 AQLLA----VLVGcMLFVALVVNPLIVFWKIRRNPYplVFT-CLRESGVTAFFTRSSAANIPVNMA-LCEKLGLDEDTYS 287
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462603775 282 FVLPVGATINMDGtalyealAAIFI-----AQVNNF--ELNFGQIITISITATAASIGAAGI 336
Cdd:PRK13628  288 VSIPLGATINMAG-------AAITItvltlAAVHTLgiPVDLPTALLLSVVAAISACGASGV 342
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
126-337 2.42e-14

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 74.44  E-value: 2.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 126 PVPGSVNGvNALGLVVFSMCFGFVignMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMedmGVigG 205
Cdd:COG3633   137 PVNALANA-NYIGILAWAIGLGLA---LRHASDTTKTVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATT---GF--S 207
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462603775 206 QLAMYT--VTVIVG-LLIHAVIVLPLLYFLVTRKNPW--VFIGgLLQALITALGTSSSSATLPITFKcLEENNGVDKRVT 280
Cdd:COG3633   208 ALLGYAhlLAVLVGcMLFVALVVNPLIVFLKIRRNPYplVFTC-LRESGITAFFTRSSAANIPVNMA-LCEKLGLDEDTY 285
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462603775 281 RFVLPVGATINMDGtalyealAAIFI-----AQVN--NFELNFGQIITISITATAASIGAAGIP 337
Cdd:COG3633   286 SVSIPLGATINMAG-------AAITItvltlAAVHtlGIEVDLPTALLLSVVAAVSACGASGVA 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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