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coiled-coil domain-containing protein 146 isoform X8 [Homo sapiens]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
Smc super family
cl34174 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
22-292
2.49e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
COG1196 :Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 57.64
E-value: 2.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 22 E M E KKMKI L RESTE EL RK E IMQKK LE IKN L RED L ASK Q KQLLKEQK EL EE L LGHQVV L KDEVA hhqtipv QIGKEI E KIT 101
Cdd:COG1196 250 E L E AELEE L EAELA EL EA E LEELR LE LEE L ELE L EEA Q AEEYELLA EL AR L EQDIAR L EERRR ------- ELEERL E ELE 322
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 102 RKKV E M E KKKIV LE Q E VKT L NDS L KKV E N kvsaivd E K E NVIK E VEGKRAL L EIK E R E HNQLVKL LE LAR E NEATS L TER 181
Cdd:COG1196 323 EELA E L E EELEE LE E E LEE L EEE L EEA E E ------- E L E EAEA E LAEAEEA L LEA E A E LAEAEEE LE ELA E ELLEA L RAA 395
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 182 GI L DLN L RNSLIDKQNYHDE L S R KQR E K E RDFRN L RKM E LLLKVSWD AL RQTQALHQR L LL E M EA IPKDDST L S E RRRE L 261
Cdd:COG1196 396 AE L AAQ L EELEEAEEALLER L E R LEE E L E ELEEA L AEL E EEEEEEEE AL EEAAEEEAE L EE E E EA LLELLAE L L E EAAL L 475
250 260 270
....*....|....*....|....*....|.
gi 2462615508 262 HKEVEVAKRN LA QQKIISEMESKLVEQQLAE 292
Cdd:COG1196 476 EAALAELLEE LA EAAARLLLLLEAEADYEGF 506
SMC_prok_B super family
cl37069 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
35-696
2.02e-07
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
TIGR02168 :Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 55.06
E-value: 2.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 35 EELR K E IMQKKL E I K NLR E D L ASKQKQ L LKEQKE LEEL LGHQVV L KD E VAHH Q TIPVQIGK EI EKITRK K VEMEKKKIV L 114
Cdd:TIGR02168 235 EELR E E LEELQE E L K EAE E E L EELTAE L QELEEK LEEL RLEVSE L EE E IEEL Q KELYALAN EI SRLEQQ K QILRERLAN L 314
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 115 E QEVKT L NDS L KKV E N K ------- VSAIVDEK E NVIK E V E GKR A L LE IK E R E HNQ L VKL LE LAR E ----- NEATSLT E RG 182
Cdd:TIGR02168 315 E RQLEE L EAQ L EEL E S K ldelaee LAELEEKL E ELKE E L E SLE A E LE EL E A E LEE L ESR LE ELE E qletl RSKVAQL E LQ 394
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 183 I LD LN LRNSLIDKQNYHD E LS R KQREK E RDFRNLRKM E LL LK VSWDA L RQTQALHQR L LL E M E AIPKDDST L S E RRR E LH 262
Cdd:TIGR02168 395 I AS LN NEIERLEARLERL E DR R ERLQQ E IEELLKKLE E AE LK ELQAE L EELEEELEE L QE E L E RLEEALEE L R E ELE E AE 474
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 263 KEVEV A K R N LAQ QKIISEMESK L V E -- QQLA E EN K L L KEQENMKELVVNL L r MTQ I KI DE KEQKSK -------------- 326
Cdd:TIGR02168 475 QALDA A E R E LAQ LQARLDSLER L Q E nl EGFS E GV K A L LKNQSGLSGILGV L - SEL I SV DE GYEAAI eaalggrlqavvve 553
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 327 --------- D FLK - AQQKYTNIVKEMKA K DL EI RIHKKKKCEIYRRLREF AK LYDTIRNERN K FVNL L HKAHQK V NEIKE 396
Cdd:TIGR02168 554 nlnaakkai A FLK q NELGRVTFLPLDSI K GT EI QGNDREILKNIEGFLGV AK DLVKFDPKLR K ALSY L LGGVLV V DDLDN 633
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 397 ---- RH K MSLNEL ------ EIL R NSA V S -- QER K LQN S M L KH ---- ANNVTIR E SMQNDVRKIVSK L Q E MKEKK E AQLNN 460
Cdd:TIGR02168 634 alel AK K LRPGYR ivtldg DLV R PGG V I tg GSA K TNS S I L ER rrei EELEEKI E ELEEKIAELEKA L A E LRKEL E ELEEE 713
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 461 IDR L ANTITMIEEEMVQ LRK RYEKAVQHRNESGVQLIEREE E ICIFYEK I NIQ E KMKLNG E I E IHLL E EK I QF L KMK I AE 540
Cdd:TIGR02168 714 LEQ L RKELEELSRQISA LRK DLARLEAEVEQLEERIAQLSK E LTELEAE I EEL E ERLEEA E E E LAEA E AE I EE L EAQ I EQ 793
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 541 KQRQI cvt QK L LP A KRS L D A D L AV L QIQFSQCTD R IKD LE KQFVKPDGENRARFLPGKD L T E K -- EMIQKLDK LE LQLAK 618
Cdd:TIGR02168 794 LKEEL --- KA L RE A LDE L R A E L TL L NEEAANLRE R LES LE RRIAATERRLEDLEEQIEE L S E D ie SLAAEIEE LE ELIEE 870
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462615508 619 K E EK L LEKDFIYEQVSRLTDR L C S KTQGCKQDTLL L AK K MNGYQ R RIKNAT EK MMA L VAE L SMKQALTIE LQ KEVR E K 696
Cdd:TIGR02168 871 L E SE L EALLNERASLEEALAL L R S ELEELSEELRE L ES K RSELR R ELEELR EK LAQ L ELR L EGLEVRIDN LQ ERLS E E 948
Name
Accession
Description
Interval
E-value
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
22-292
2.49e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 57.64
E-value: 2.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 22 E M E KKMKI L RESTE EL RK E IMQKK LE IKN L RED L ASK Q KQLLKEQK EL EE L LGHQVV L KDEVA hhqtipv QIGKEI E KIT 101
Cdd:COG1196 250 E L E AELEE L EAELA EL EA E LEELR LE LEE L ELE L EEA Q AEEYELLA EL AR L EQDIAR L EERRR ------- ELEERL E ELE 322
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 102 RKKV E M E KKKIV LE Q E VKT L NDS L KKV E N kvsaivd E K E NVIK E VEGKRAL L EIK E R E HNQLVKL LE LAR E NEATS L TER 181
Cdd:COG1196 323 EELA E L E EELEE LE E E LEE L EEE L EEA E E ------- E L E EAEA E LAEAEEA L LEA E A E LAEAEEE LE ELA E ELLEA L RAA 395
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 182 GI L DLN L RNSLIDKQNYHDE L S R KQR E K E RDFRN L RKM E LLLKVSWD AL RQTQALHQR L LL E M EA IPKDDST L S E RRRE L 261
Cdd:COG1196 396 AE L AAQ L EELEEAEEALLER L E R LEE E L E ELEEA L AEL E EEEEEEEE AL EEAAEEEAE L EE E E EA LLELLAE L L E EAAL L 475
250 260 270
....*....|....*....|....*....|.
gi 2462615508 262 HKEVEVAKRN LA QQKIISEMESKLVEQQLAE 292
Cdd:COG1196 476 EAALAELLEE LA EAAARLLLLLEAEADYEGF 506
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
35-696
2.02e-07
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 55.06
E-value: 2.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 35 EELR K E IMQKKL E I K NLR E D L ASKQKQ L LKEQKE LEEL LGHQVV L KD E VAHH Q TIPVQIGK EI EKITRK K VEMEKKKIV L 114
Cdd:TIGR02168 235 EELR E E LEELQE E L K EAE E E L EELTAE L QELEEK LEEL RLEVSE L EE E IEEL Q KELYALAN EI SRLEQQ K QILRERLAN L 314
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 115 E QEVKT L NDS L KKV E N K ------- VSAIVDEK E NVIK E V E GKR A L LE IK E R E HNQ L VKL LE LAR E ----- NEATSLT E RG 182
Cdd:TIGR02168 315 E RQLEE L EAQ L EEL E S K ldelaee LAELEEKL E ELKE E L E SLE A E LE EL E A E LEE L ESR LE ELE E qletl RSKVAQL E LQ 394
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 183 I LD LN LRNSLIDKQNYHD E LS R KQREK E RDFRNLRKM E LL LK VSWDA L RQTQALHQR L LL E M E AIPKDDST L S E RRR E LH 262
Cdd:TIGR02168 395 I AS LN NEIERLEARLERL E DR R ERLQQ E IEELLKKLE E AE LK ELQAE L EELEEELEE L QE E L E RLEEALEE L R E ELE E AE 474
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 263 KEVEV A K R N LAQ QKIISEMESK L V E -- QQLA E EN K L L KEQENMKELVVNL L r MTQ I KI DE KEQKSK -------------- 326
Cdd:TIGR02168 475 QALDA A E R E LAQ LQARLDSLER L Q E nl EGFS E GV K A L LKNQSGLSGILGV L - SEL I SV DE GYEAAI eaalggrlqavvve 553
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 327 --------- D FLK - AQQKYTNIVKEMKA K DL EI RIHKKKKCEIYRRLREF AK LYDTIRNERN K FVNL L HKAHQK V NEIKE 396
Cdd:TIGR02168 554 nlnaakkai A FLK q NELGRVTFLPLDSI K GT EI QGNDREILKNIEGFLGV AK DLVKFDPKLR K ALSY L LGGVLV V DDLDN 633
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 397 ---- RH K MSLNEL ------ EIL R NSA V S -- QER K LQN S M L KH ---- ANNVTIR E SMQNDVRKIVSK L Q E MKEKK E AQLNN 460
Cdd:TIGR02168 634 alel AK K LRPGYR ivtldg DLV R PGG V I tg GSA K TNS S I L ER rrei EELEEKI E ELEEKIAELEKA L A E LRKEL E ELEEE 713
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 461 IDR L ANTITMIEEEMVQ LRK RYEKAVQHRNESGVQLIEREE E ICIFYEK I NIQ E KMKLNG E I E IHLL E EK I QF L KMK I AE 540
Cdd:TIGR02168 714 LEQ L RKELEELSRQISA LRK DLARLEAEVEQLEERIAQLSK E LTELEAE I EEL E ERLEEA E E E LAEA E AE I EE L EAQ I EQ 793
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 541 KQRQI cvt QK L LP A KRS L D A D L AV L QIQFSQCTD R IKD LE KQFVKPDGENRARFLPGKD L T E K -- EMIQKLDK LE LQLAK 618
Cdd:TIGR02168 794 LKEEL --- KA L RE A LDE L R A E L TL L NEEAANLRE R LES LE RRIAATERRLEDLEEQIEE L S E D ie SLAAEIEE LE ELIEE 870
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462615508 619 K E EK L LEKDFIYEQVSRLTDR L C S KTQGCKQDTLL L AK K MNGYQ R RIKNAT EK MMA L VAE L SMKQALTIE LQ KEVR E K 696
Cdd:TIGR02168 871 L E SE L EALLNERASLEEALAL L R S ELEELSEELRE L ES K RSELR R ELEELR EK LAQ L ELR L EGLEVRIDN LQ ERLS E E 948
SMC_N
pfam02463 RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
23-749
1.17e-06
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain]
Cd Length: 1161
Bit Score: 52.28
E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 23 MEKKMKILR E STEELR KE IMQKKL E I K NLR E D L ASKQ K QLLKEQK EL EE L LGHQ V VLKDEVAHHQTIPVQIG KE IE K ITR 102
Cdd:pfam02463 256 SKQEIEKEE E KLAQVL KE NKEEEK E K K LQE E E L KLLA K EEEELKS EL LK L ERRK V DDEEKLKESEKEKKKAE KE LK K EKE 335
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 103 KKV E M EK KKIV L ----------- E QEV K TLNDSLKKV E NKVSAIVD E K E NVIKEVEG K RAL LE I K ER E HNQLVK LLELAR 171
Cdd:pfam02463 336 EIE E L EK ELKE L eikreaeeeee E ELE K LQEKLEQLE E ELLAKKKL E S E RLSSAAKL K EEE LE L K SE E EKEAQL LLELAR 415
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 172 EN E -- ATSLTERGILD L NLRNSL I DKQNYHDELSRKQR EK ERDFRNLRKM EL LLKVSWDALR Q TQA L HQR L L L EMEAIPK 249
Cdd:pfam02463 416 QL E dl LKEEKKEELEI L EEEEES I ELKQGKLTEEKEEL EK QELKLLKDEL EL KKSEDLLKET Q LVK L QEQ L E L LLSRQKL 495
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 250 DDSTLS E R rrelh K EVEVA K RN LA QQ K IISEMESKLVEQQ L AEENKLLKEQENMKELV V NLLRMTQIKID E KE QK SKDF L 329
Cdd:pfam02463 496 EERSQK E S ----- K ARSGL K VL LA LI K DGVGGRIISAHGR L GDLGVAVENYKVAISTA V IVEVSATADEV E ER QK LVRA L 570
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 330 KAQQKYTNIVKEMKA K DLEIRIHKKKKCEIYRRLREFAKLYDTIRN E RN K FVNLLHKAHQKVNEI K ER ---------- H K 399
Cdd:pfam02463 571 TELPLGARKLRLLIP K LKLPLKSIAVLEIDPILNLAQLDKATLEAD E DD K RAKVVEGILKDTELT K LK esakakesgl R K 650
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 400 MSLN E LEILRN S A V SQERKLQNSM L KHANNVTIRESMQNDVRK I VSKLQ E M K E K KEAQLNNIDR L ANTITMIEEEM VQ L r 479
Cdd:pfam02463 651 GVSL E EGLAEK S E V KASLSELTKE L LEIQELQEKAESELAKEE I LRRQL E I K K K EQREKEELKK L KLEAEELLADR VQ E - 729
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 480 KRYEKAVQHRNESGVQLI E R EEE ICIFYE K INIQ E KMKLNGEI E IH L L EE KIQFL K M K IA E KQRQICVT Q KLLPAKRSLD 559
Cdd:pfam02463 730 AQDKINEELKLLKQKIDE E E EEE EKSRLK K EEKE E EKSELSLK E KE L A EE REKTE K L K VE E EKEEKLKA Q EEELRALEEE 809
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 560 ADLAVLQIQFS Q CTDRIKDLE K QFV --- KPDGENRARF L PGKDLT E K E MIQKLDKL E LQ L AKKEE K LL E KDFI y EQVSR L 636
Cdd:pfam02463 810 LKEEAELLEEE Q LLIEQEEKI K EEE lee LALELKEEQK L EKLAEE E L E RLEEEITK E EL L QELLL K EE E LEEQ - KLKDE L 888
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 637 TDRLCSKTQGC K QDTLLLA K KMNGYQRRIKNA - TE K MM A LVAELSMKQALTIE L QKEVREKEDFIFTCNSRIEKGLP L NK 715
Cdd:pfam02463 889 ESKEEKEKEEK K ELEEESQ K LNLLEEKENEIE e RI K EE A EILLKYEEEPEELL L EEADEKEKEENNKEEEEERNKRL L LA 968
730 740 750
....*....|....*....|....*....|....
gi 2462615508 716 EI E KEWLKVLRD EE MHALAIAEKSQ E FLEADNRQ 749
Cdd:pfam02463 969 KE E LGKVNLMAI EE FEEKEERYNKD E LEKERLEE 1002
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
21-344
1.04e-05
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 49.28
E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 21 G E M E KKM K I L REST E elrkeimq K KLEI K N L RED L ASKQKQ LL K ----- EQK ELEEL LGHQVVLKD E VAHHQTIPVQIGK 95
Cdd:TIGR02168 196 N E L E RQL K S L ERQA E -------- K AERY K E L KAE L RELELA LL V lrlee LRE ELEEL QEELKEAEE E LEELTAELQELEE 267
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 96 EI E KITRKKV E M E KKKIV L EQ E VKT L NDSLKKV E NKVSAIVDEKE N VIKEV E GKR A L LE IK E REHNQ L VKL L ELAR E NEA 175
Cdd:TIGR02168 268 KL E ELRLEVS E L E EEIEE L QK E LYA L ANEISRL E QQKQILRERLA N LERQL E ELE A Q LE EL E SKLDE L AEE L AELE E KLE 347
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 176 TSLT E R gild LN L RNS L IDKQNYHD EL SRKQR E K E RDFRN LR KME lllkvsw DA L RQTQ A LHQRLLLEM EA IPKD dst L S 255
Cdd:TIGR02168 348 ELKE E L ---- ES L EAE L EELEAELE EL ESRLE E L E EQLET LR SKV ------- AQ L ELQI A SLNNEIERL EA RLER --- L E 413
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 256 E RR RE L HK E V E vakrnl AQQ K IIS E M E S K LVEQQ L A E ENKL L K E QENMK E LVVNL L RMTQIKID E K EQ KSKDFLKAQQKY 335
Cdd:TIGR02168 414 D RR ER L QQ E I E ------ ELL K KLE E A E L K ELQAE L E E LEEE L E E LQEEL E RLEEA L EELREELE E A EQ ALDAAERELAQL 487
....*....
gi 2462615508 336 TNIVKEMKA 344
Cdd:TIGR02168 488 QARLDSLER 496
PTZ00121
PTZ00121 MAEBL; Provisional
12-476
2.39e-05
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 48.21
E-value: 2.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 12 K EF E KIT K PG E ME KK MKILRESTEELR K -- E IMQ K KL E IKNLREDL A SKQKQLLK E QK E LE E LLGHQVVL K DEV A HHQTI 89
Cdd:PTZ00121 1309 K KA E EAK K AD E AK KK AEEAKKKADAAK K ka E EAK K AA E AAKAEAEA A ADEAEAAE E KA E AA E KKKEEAKK K ADA A KKKAE 1388
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 90 PVQIGK E IE K ITR --------- KK VEME KKK I ---- VLEQ E V K TLNDSL KK V E NKVS A IVDE K -------- E NVI K EV E G 148
Cdd:PTZ00121 1389 EKKKAD E AK K KAE edkkkadel KK AAAA KKK A deak KKAE E K K KADEAK KK A E EAKK A DEAK K kaeeakka E EAK K KA E E 1468
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 149 KRALL E I K E ----- REHNQLV K LL E L A RE -- N EA TSLT E RGILDLNLRNS li DKQNYH DE L sr K QR E KERDFRNLR K M E L 221
Cdd:PTZ00121 1469 AKKAD E A K K kaeea KKADEAK K KA E E A KK ka D EA KKAA E AKKKADEAKKA -- EEAKKA DE A -- K KA E EAKKADEAK K A E E 1544
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 222 LL K V sw D A L RQTQA L --- HQRLLL E MEAIPKD D STLSE R RR E LH K EV E V A KRNLAQQKIIS E MES K LV E QQL AEE N K LLK 298
Cdd:PTZ00121 1545 KK K A -- D E L KKAEE L kka EEKKKA E EAKKAEE D KNMAL R KA E EA K KA E E A RIEEVMKLYEE E KKM K AE E AKK AEE A K IKA 1622
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 299 E QENMK E LVVNLLRMTQI K ID E KEQ K SKDFL KA QQKYTNIVK E MKA K DL E irih K KKK C E IYRRLR E faklydtir N E RN 378
Cdd:PTZ00121 1623 E ELKKA E EEKKKVEQLKK K EA E EKK K AEELK KA EEENKIKAA E EAK K AE E ---- D KKK A E EAKKAE E --------- D E KK 1689
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 379 KFVN L LHK A HQ -- K VN E I K ERHKMSLNEL E I L RNS av SQ E R K LQNSML K hannvti R E SMQNDVRKIVS K LQ E MKE KK E A 456
Cdd:PTZ00121 1690 AAEA L KKE A EE ak K AE E L K KKEAEEKKKA E E L KKA -- EE E N K IKAEEA K ------- K E AEEDKKKAEEA K KD E EEK KK I A 1760
490 500
....*....|....*....|
gi 2462615508 457 Q L NNIDRLANTITMI E E E M V 476
Cdd:PTZ00121 1761 H L KKEEEKKAEEIRK E K E A V 1780
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
355-626
3.66e-03
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 41.08
E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 355 K K C E I YR R L R E FA K LYD tirne RNKFVNL L HKAHQKVN E IKERHKMSLN ELE I L RNSAVSQ E RK L QNSM L KHANNVTIR E 434
Cdd:COG1196 210 E K A E R YR E L K E EL K ELE ----- AELLLLK L RELEAELE E LEAELEELEA ELE E L EAELAEL E AE L EELR L ELEELELEL E 284
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 435 SM Q NDVRKIVSK L QEMKEKKEAQLNNIDR L ANTITMI EEE MVQ L RKRY E KAVQHRN E SGVQ L I E R EEE ICIFYEKINIQ E 514
Cdd:COG1196 285 EA Q AEEYELLAE L ARLEQDIARLEERRRE L EERLEEL EEE LAE L EEEL E ELEEELE E LEEE L E E A EEE LEEAEAELAEA E 364
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 515 KMK L NG E I E IHLL EE KIQF L KMKIA E KQ R QICVTQKL L PAKRSLDAD L AVLQIQFSQCTDRIKDLEKQFVKPDG E NRA rf 594
Cdd:COG1196 365 EAL L EA E A E LAEA EE ELEE L AEELL E AL R AAAELAAQ L EELEEAEEA L LERLERLEEELEELEEALAELEEEEE E EEE -- 442
250 260 270
....*....|....*....|....*....|..
gi 2462615508 595 lpg KDLTEK E MIQK L DKL E LQ L AKKEEK LLE K 626
Cdd:COG1196 443 --- ALEEAA E EEAE L EEE E EA L LELLAE LLE E 471
PTZ00121
PTZ00121 MAEBL; Provisional
6-627
3.94e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 40.89
E-value: 3.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 6 E KIIIVKEF E KITKPG E ME KK MKILRESTEELRK E IMQ K KLEIKNLR E DLASKQKQLLK E QKEL E ELLGHQVVL K D E V A H 85
Cdd:PTZ00121 1085 E DNRADEAT E EAFGKA E EA KK TETGKAEEARKAE E AKK K AEDARKAE E ARKAEDARKAE E ARKA E DAKRVEIAR K A E D A R 1164
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 86 HQTIP -- VQIG K EI E K i T RK KV E ME K KKIVLEQ E VKTLNDSLK K V E NKVS A IVDE K ENVI K EV E GKRALL E I K EREH n QL 163
Cdd:PTZ00121 1165 KAEEA rk AEDA K KA E A - A RK AE E VR K AEELRKA E DARKAEAAR K A E EERK A EEAR K AEDA K KA E AVKKAE E A K KDAE - EA 1242
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 164 V K LL E LAREN E ATSLT E RGILDLNL R NSL I DKQNYHDELSR K QR E KERDFRNLR K M E LLL K VSWDALRQTQ A LH - QRLLL 242
Cdd:PTZ00121 1243 K K AE E ERNNE E IRKFE E ARMAHFAR R QAA I KAEEARKADEL K KA E EKKKADEAK K A E EKK K ADEAKKKAEE A KK a DEAKK 1322
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 243 EM E AIP K DDSTLSERRR E LH K EV E V AK RNLAQQKIIS E MESKLV E QQLAEENKLL K EQENM K ELVVNLLRMTQI K IDEK E 322
Cdd:PTZ00121 1323 KA E EAK K KADAAKKKAE E AK K AA E A AK AEAEAAADEA E AAEEKA E AAEKKKEEAK K KADAA K KKAEEKKKADEA K KKAE E 1402
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 323 Q K S K - D F LK AQQKYTNIVK E M K A K DL E IRIHK -- KKK C E IYRRLR E FA K LYD tirn E RN K FVNLLH KA HQ -- K VN E I K ER 397
Cdd:PTZ00121 1403 D K K K a D E LK KAAAAKKKAD E A K K K AE E KKKAD ea KKK A E EAKKAD E AK K KAE ---- E AK K AEEAKK KA EE ak K AD E A K KK 1478
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 398 HKMS l NELEILRNS A VSQER K LQNSMLKHANNVTIR E SMQNDVR K IVSKLQEMK E K K E A - QLNNIDRLANTITMIEE E MV 476
Cdd:PTZ00121 1479 AEEA - KKADEAKKK A EEAKK K ADEAKKAAEAKKKAD E AKKAEEA K KADEAKKAE E A K K A d EAKKAEEKKKADELKKA E EL 1557
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 477 QLRKRYE KA VQ - HRN E SGVQLIE R EE E ICIFY E KIN I Q E K MKL NG E ieihll E E K IQFLKM K I AE KQR qicvt Q K LLPA K 555
Cdd:PTZ00121 1558 KKAEEKK KA EE a KKA E EDKNMAL R KA E EAKKA E EAR I E E V MKL YE E ------ E K K MKAEEA K K AE EAK ----- I K AEEL K 1626
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462615508 556 RSLDADLA V L Q IQFSQCTDRI K DL E KQFVKPDGENR A RFLPG K DLTE K EMIQKLD K L E LQLA K KE E K L LEKD 627
Cdd:PTZ00121 1627 KAEEEKKK V E Q LKKKEAEEKK K AE E LKKAEEENKIK A AEEAK K AEED K KKAEEAK K A E EDEK K AA E A L KKEA 1698
Name
Accession
Description
Interval
E-value
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
22-292
2.49e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 57.64
E-value: 2.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 22 E M E KKMKI L RESTE EL RK E IMQKK LE IKN L RED L ASK Q KQLLKEQK EL EE L LGHQVV L KDEVA hhqtipv QIGKEI E KIT 101
Cdd:COG1196 250 E L E AELEE L EAELA EL EA E LEELR LE LEE L ELE L EEA Q AEEYELLA EL AR L EQDIAR L EERRR ------- ELEERL E ELE 322
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 102 RKKV E M E KKKIV LE Q E VKT L NDS L KKV E N kvsaivd E K E NVIK E VEGKRAL L EIK E R E HNQLVKL LE LAR E NEATS L TER 181
Cdd:COG1196 323 EELA E L E EELEE LE E E LEE L EEE L EEA E E ------- E L E EAEA E LAEAEEA L LEA E A E LAEAEEE LE ELA E ELLEA L RAA 395
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 182 GI L DLN L RNSLIDKQNYHDE L S R KQR E K E RDFRN L RKM E LLLKVSWD AL RQTQALHQR L LL E M EA IPKDDST L S E RRRE L 261
Cdd:COG1196 396 AE L AAQ L EELEEAEEALLER L E R LEE E L E ELEEA L AEL E EEEEEEEE AL EEAAEEEAE L EE E E EA LLELLAE L L E EAAL L 475
250 260 270
....*....|....*....|....*....|.
gi 2462615508 262 HKEVEVAKRN LA QQKIISEMESKLVEQQLAE 292
Cdd:COG1196 476 EAALAELLEE LA EAAARLLLLLEAEADYEGF 506
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
35-696
2.02e-07
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 55.06
E-value: 2.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 35 EELR K E IMQKKL E I K NLR E D L ASKQKQ L LKEQKE LEEL LGHQVV L KD E VAHH Q TIPVQIGK EI EKITRK K VEMEKKKIV L 114
Cdd:TIGR02168 235 EELR E E LEELQE E L K EAE E E L EELTAE L QELEEK LEEL RLEVSE L EE E IEEL Q KELYALAN EI SRLEQQ K QILRERLAN L 314
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 115 E QEVKT L NDS L KKV E N K ------- VSAIVDEK E NVIK E V E GKR A L LE IK E R E HNQ L VKL LE LAR E ----- NEATSLT E RG 182
Cdd:TIGR02168 315 E RQLEE L EAQ L EEL E S K ldelaee LAELEEKL E ELKE E L E SLE A E LE EL E A E LEE L ESR LE ELE E qletl RSKVAQL E LQ 394
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 183 I LD LN LRNSLIDKQNYHD E LS R KQREK E RDFRNLRKM E LL LK VSWDA L RQTQALHQR L LL E M E AIPKDDST L S E RRR E LH 262
Cdd:TIGR02168 395 I AS LN NEIERLEARLERL E DR R ERLQQ E IEELLKKLE E AE LK ELQAE L EELEEELEE L QE E L E RLEEALEE L R E ELE E AE 474
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 263 KEVEV A K R N LAQ QKIISEMESK L V E -- QQLA E EN K L L KEQENMKELVVNL L r MTQ I KI DE KEQKSK -------------- 326
Cdd:TIGR02168 475 QALDA A E R E LAQ LQARLDSLER L Q E nl EGFS E GV K A L LKNQSGLSGILGV L - SEL I SV DE GYEAAI eaalggrlqavvve 553
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 327 --------- D FLK - AQQKYTNIVKEMKA K DL EI RIHKKKKCEIYRRLREF AK LYDTIRNERN K FVNL L HKAHQK V NEIKE 396
Cdd:TIGR02168 554 nlnaakkai A FLK q NELGRVTFLPLDSI K GT EI QGNDREILKNIEGFLGV AK DLVKFDPKLR K ALSY L LGGVLV V DDLDN 633
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 397 ---- RH K MSLNEL ------ EIL R NSA V S -- QER K LQN S M L KH ---- ANNVTIR E SMQNDVRKIVSK L Q E MKEKK E AQLNN 460
Cdd:TIGR02168 634 alel AK K LRPGYR ivtldg DLV R PGG V I tg GSA K TNS S I L ER rrei EELEEKI E ELEEKIAELEKA L A E LRKEL E ELEEE 713
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 461 IDR L ANTITMIEEEMVQ LRK RYEKAVQHRNESGVQLIEREE E ICIFYEK I NIQ E KMKLNG E I E IHLL E EK I QF L KMK I AE 540
Cdd:TIGR02168 714 LEQ L RKELEELSRQISA LRK DLARLEAEVEQLEERIAQLSK E LTELEAE I EEL E ERLEEA E E E LAEA E AE I EE L EAQ I EQ 793
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 541 KQRQI cvt QK L LP A KRS L D A D L AV L QIQFSQCTD R IKD LE KQFVKPDGENRARFLPGKD L T E K -- EMIQKLDK LE LQLAK 618
Cdd:TIGR02168 794 LKEEL --- KA L RE A LDE L R A E L TL L NEEAANLRE R LES LE RRIAATERRLEDLEEQIEE L S E D ie SLAAEIEE LE ELIEE 870
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462615508 619 K E EK L LEKDFIYEQVSRLTDR L C S KTQGCKQDTLL L AK K MNGYQ R RIKNAT EK MMA L VAE L SMKQALTIE LQ KEVR E K 696
Cdd:TIGR02168 871 L E SE L EALLNERASLEEALAL L R S ELEELSEELRE L ES K RSELR R ELEELR EK LAQ L ELR L EGLEVRIDN LQ ERLS E E 948
SMC_N
pfam02463 RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
23-749
1.17e-06
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain]
Cd Length: 1161
Bit Score: 52.28
E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 23 MEKKMKILR E STEELR KE IMQKKL E I K NLR E D L ASKQ K QLLKEQK EL EE L LGHQ V VLKDEVAHHQTIPVQIG KE IE K ITR 102
Cdd:pfam02463 256 SKQEIEKEE E KLAQVL KE NKEEEK E K K LQE E E L KLLA K EEEELKS EL LK L ERRK V DDEEKLKESEKEKKKAE KE LK K EKE 335
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 103 KKV E M EK KKIV L ----------- E QEV K TLNDSLKKV E NKVSAIVD E K E NVIKEVEG K RAL LE I K ER E HNQLVK LLELAR 171
Cdd:pfam02463 336 EIE E L EK ELKE L eikreaeeeee E ELE K LQEKLEQLE E ELLAKKKL E S E RLSSAAKL K EEE LE L K SE E EKEAQL LLELAR 415
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 172 EN E -- ATSLTERGILD L NLRNSL I DKQNYHDELSRKQR EK ERDFRNLRKM EL LLKVSWDALR Q TQA L HQR L L L EMEAIPK 249
Cdd:pfam02463 416 QL E dl LKEEKKEELEI L EEEEES I ELKQGKLTEEKEEL EK QELKLLKDEL EL KKSEDLLKET Q LVK L QEQ L E L LLSRQKL 495
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 250 DDSTLS E R rrelh K EVEVA K RN LA QQ K IISEMESKLVEQQ L AEENKLLKEQENMKELV V NLLRMTQIKID E KE QK SKDF L 329
Cdd:pfam02463 496 EERSQK E S ----- K ARSGL K VL LA LI K DGVGGRIISAHGR L GDLGVAVENYKVAISTA V IVEVSATADEV E ER QK LVRA L 570
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 330 KAQQKYTNIVKEMKA K DLEIRIHKKKKCEIYRRLREFAKLYDTIRN E RN K FVNLLHKAHQKVNEI K ER ---------- H K 399
Cdd:pfam02463 571 TELPLGARKLRLLIP K LKLPLKSIAVLEIDPILNLAQLDKATLEAD E DD K RAKVVEGILKDTELT K LK esakakesgl R K 650
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 400 MSLN E LEILRN S A V SQERKLQNSM L KHANNVTIRESMQNDVRK I VSKLQ E M K E K KEAQLNNIDR L ANTITMIEEEM VQ L r 479
Cdd:pfam02463 651 GVSL E EGLAEK S E V KASLSELTKE L LEIQELQEKAESELAKEE I LRRQL E I K K K EQREKEELKK L KLEAEELLADR VQ E - 729
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 480 KRYEKAVQHRNESGVQLI E R EEE ICIFYE K INIQ E KMKLNGEI E IH L L EE KIQFL K M K IA E KQRQICVT Q KLLPAKRSLD 559
Cdd:pfam02463 730 AQDKINEELKLLKQKIDE E E EEE EKSRLK K EEKE E EKSELSLK E KE L A EE REKTE K L K VE E EKEEKLKA Q EEELRALEEE 809
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 560 ADLAVLQIQFS Q CTDRIKDLE K QFV --- KPDGENRARF L PGKDLT E K E MIQKLDKL E LQ L AKKEE K LL E KDFI y EQVSR L 636
Cdd:pfam02463 810 LKEEAELLEEE Q LLIEQEEKI K EEE lee LALELKEEQK L EKLAEE E L E RLEEEITK E EL L QELLL K EE E LEEQ - KLKDE L 888
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 637 TDRLCSKTQGC K QDTLLLA K KMNGYQRRIKNA - TE K MM A LVAELSMKQALTIE L QKEVREKEDFIFTCNSRIEKGLP L NK 715
Cdd:pfam02463 889 ESKEEKEKEEK K ELEEESQ K LNLLEEKENEIE e RI K EE A EILLKYEEEPEELL L EEADEKEKEENNKEEEEERNKRL L LA 968
730 740 750
....*....|....*....|....*....|....
gi 2462615508 716 EI E KEWLKVLRD EE MHALAIAEKSQ E FLEADNRQ 749
Cdd:pfam02463 969 KE E LGKVNLMAI EE FEEKEERYNKD E LEKERLEE 1002
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
15-626
3.92e-06
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 50.83
E-value: 3.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 15 E KITKPG E M E KKMKI L RESTEE L RK EI MQKKLEIKN LRE D LA SKQK QL LKEQKE LEEL LGHQVV L KD E V A HHQTIPVQIG 94
Cdd:TIGR02168 271 E LRLEVS E L E EEIEE L QKELYA L AN EI SRLEQQKQI LRE R LA NLER QL EELEAQ LEEL ESKLDE L AE E L A ELEEKLEELK 350
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 95 K E I E KITRKKV E M E KKKIV LE QEVKT L NDS L KKVEN KV SAIVDEKENVIK E V E GKR A L LE IK E REHNQ L V -------- KL 166
Cdd:TIGR02168 351 E E L E SLEAELE E L E AELEE LE SRLEE L EEQ L ETLRS KV AQLELQIASLNN E I E RLE A R LE RL E DRRER L Q qeieellk KL 430
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 167 L E LARENEATS L T E RGILDLN L RNS L IDKQNYHD EL SRKQR E K E RDFRNLRKMELL L KVSW D A L RQT Q ALHQ ------- R 239
Cdd:TIGR02168 431 E E AELKELQAE L E E LEEELEE L QEE L ERLEEALE EL REELE E A E QALDAAERELAQ L QARL D S L ERL Q ENLE gfsegvk A 510
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 240 LL LEMEAIPKDDST LSE R --- RRELHKEV E V A KRNLA Q QKIISEMESKLVEQQLAEE N K L LK ------ EQENMK E LVV N L 310
Cdd:TIGR02168 511 LL KNQSGLSGILGV LSE L isv DEGYEAAI E A A LGGRL Q AVVVENLNAAKKAIAFLKQ N E L GR vtflpl DSIKGT E IQG N D 590
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 311 LRMTQ ------------ I K I D E K EQ K SKDF L ------------------ K AQQK Y TNIVKE ------------------- 341
Cdd:TIGR02168 591 REILK niegflgvakdl V K F D P K LR K ALSY L lggvlvvddldnalelak K LRPG Y RIVTLD gdlvrpggvitggsaktns 670
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 342 - MKAKDL EI RIHKK K KC E IYRRLR E FA K LYDTI R N E RNKFVNL L HKAHQKVN E IKERHKMSLNE L EI L RNSAVSQ E RKLQ 420
Cdd:TIGR02168 671 s ILERRR EI EELEE K IE E LEEKIA E LE K ALAEL R K E LEELEEE L EQLRKELE E LSRQISALRKD L AR L EAEVEQL E ERIA 750
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 421 NSMLKHANNVTIR E SMQNDVRKIVSK L Q E MKEKK E AQLNN I DR L ANTITMIE E EMVQ LR KRY -- EKAVQHRNESGVQLI E 498
Cdd:TIGR02168 751 QLSKELTELEAEI E ELEERLEEAEEE L A E AEAEI E ELEAQ I EQ L KEELKALR E ALDE LR AEL tl LNEEAANLRERLESL E 830
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 499 R EEEICIFYEKINIQEKMK L NGE IE I hl L EEK I QF L KMK I A E KQRQI cvt QK LL PAKR SL DAD LA V L QIQFSQCTDRIKD 578
Cdd:TIGR02168 831 R RIAATERRLEDLEEQIEE L SED IE S -- L AAE I EE L EEL I E E LESEL --- EA LL NERA SL EEA LA L L RSELEELSEELRE 905
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 2462615508 579 LE KQFVKPDG E NRA rflpg KDLTEKEMIQK L DK LE LQLAKKE E K L L E K 626
Cdd:TIGR02168 906 LE SKRSELRR E LEE ----- LREKLAQLELR L EG LE VRIDNLQ E R L S E E 948
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
21-344
1.04e-05
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 49.28
E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 21 G E M E KKM K I L REST E elrkeimq K KLEI K N L RED L ASKQKQ LL K ----- EQK ELEEL LGHQVVLKD E VAHHQTIPVQIGK 95
Cdd:TIGR02168 196 N E L E RQL K S L ERQA E -------- K AERY K E L KAE L RELELA LL V lrlee LRE ELEEL QEELKEAEE E LEELTAELQELEE 267
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 96 EI E KITRKKV E M E KKKIV L EQ E VKT L NDSLKKV E NKVSAIVDEKE N VIKEV E GKR A L LE IK E REHNQ L VKL L ELAR E NEA 175
Cdd:TIGR02168 268 KL E ELRLEVS E L E EEIEE L QK E LYA L ANEISRL E QQKQILRERLA N LERQL E ELE A Q LE EL E SKLDE L AEE L AELE E KLE 347
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 176 TSLT E R gild LN L RNS L IDKQNYHD EL SRKQR E K E RDFRN LR KME lllkvsw DA L RQTQ A LHQRLLLEM EA IPKD dst L S 255
Cdd:TIGR02168 348 ELKE E L ---- ES L EAE L EELEAELE EL ESRLE E L E EQLET LR SKV ------- AQ L ELQI A SLNNEIERL EA RLER --- L E 413
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 256 E RR RE L HK E V E vakrnl AQQ K IIS E M E S K LVEQQ L A E ENKL L K E QENMK E LVVNL L RMTQIKID E K EQ KSKDFLKAQQKY 335
Cdd:TIGR02168 414 D RR ER L QQ E I E ------ ELL K KLE E A E L K ELQAE L E E LEEE L E E LQEEL E RLEEA L EELREELE E A EQ ALDAAERELAQL 487
....*....
gi 2462615508 336 TNIVKEMKA 344
Cdd:TIGR02168 488 QARLDSLER 496
PTZ00121
PTZ00121 MAEBL; Provisional
12-476
2.39e-05
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 48.21
E-value: 2.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 12 K EF E KIT K PG E ME KK MKILRESTEELR K -- E IMQ K KL E IKNLREDL A SKQKQLLK E QK E LE E LLGHQVVL K DEV A HHQTI 89
Cdd:PTZ00121 1309 K KA E EAK K AD E AK KK AEEAKKKADAAK K ka E EAK K AA E AAKAEAEA A ADEAEAAE E KA E AA E KKKEEAKK K ADA A KKKAE 1388
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 90 PVQIGK E IE K ITR --------- KK VEME KKK I ---- VLEQ E V K TLNDSL KK V E NKVS A IVDE K -------- E NVI K EV E G 148
Cdd:PTZ00121 1389 EKKKAD E AK K KAE edkkkadel KK AAAA KKK A deak KKAE E K K KADEAK KK A E EAKK A DEAK K kaeeakka E EAK K KA E E 1468
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 149 KRALL E I K E ----- REHNQLV K LL E L A RE -- N EA TSLT E RGILDLNLRNS li DKQNYH DE L sr K QR E KERDFRNLR K M E L 221
Cdd:PTZ00121 1469 AKKAD E A K K kaeea KKADEAK K KA E E A KK ka D EA KKAA E AKKKADEAKKA -- EEAKKA DE A -- K KA E EAKKADEAK K A E E 1544
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 222 LL K V sw D A L RQTQA L --- HQRLLL E MEAIPKD D STLSE R RR E LH K EV E V A KRNLAQQKIIS E MES K LV E QQL AEE N K LLK 298
Cdd:PTZ00121 1545 KK K A -- D E L KKAEE L kka EEKKKA E EAKKAEE D KNMAL R KA E EA K KA E E A RIEEVMKLYEE E KKM K AE E AKK AEE A K IKA 1622
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 299 E QENMK E LVVNLLRMTQI K ID E KEQ K SKDFL KA QQKYTNIVK E MKA K DL E irih K KKK C E IYRRLR E faklydtir N E RN 378
Cdd:PTZ00121 1623 E ELKKA E EEKKKVEQLKK K EA E EKK K AEELK KA EEENKIKAA E EAK K AE E ---- D KKK A E EAKKAE E --------- D E KK 1689
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 379 KFVN L LHK A HQ -- K VN E I K ERHKMSLNEL E I L RNS av SQ E R K LQNSML K hannvti R E SMQNDVRKIVS K LQ E MKE KK E A 456
Cdd:PTZ00121 1690 AAEA L KKE A EE ak K AE E L K KKEAEEKKKA E E L KKA -- EE E N K IKAEEA K ------- K E AEEDKKKAEEA K KD E EEK KK I A 1760
490 500
....*....|....*....|
gi 2462615508 457 Q L NNIDRLANTITMI E E E M V 476
Cdd:PTZ00121 1761 H L KKEEEKKAEEIRK E K E A V 1780
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
95-396
3.36e-05
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 47.74
E-value: 3.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 95 K EIE KITR K KV E M E K K KIV LE QEVKT L NDS L KKV E NKVSAIVD E K E NVIKEVEGK R AL L EIK E R E HN QL VKLLELARENE 174
Cdd:TIGR02168 677 R EIE ELEE K IE E L E E K IAE LE KALAE L RKE L EEL E EELEQLRK E L E ELSRQISAL R KD L ARL E A E VE QL EERIAQLSKEL 756
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 175 ATSLT E RGI L DLN L RNSLIDKQNYHD E LSRKQREK E RDFRN L RKMELL L KVSWDA L RQTQALHQR L LLEM E AIPKDDSTL 254
Cdd:TIGR02168 757 TELEA E IEE L EER L EEAEEELAEAEA E IEELEAQI E QLKEE L KALREA L DELRAE L TLLNEEAAN L RERL E SLERRIAAT 836
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 255 SE R RRE L HKEV E VAKRNLA qq KIIS E M E S -- K L V E QQLA E ENK LL K E QENMK E LVVN L LRMTQIKID E KEQKSKDFLKAQ 332
Cdd:TIGR02168 837 ER R LED L EEQI E ELSEDIE -- SLAA E I E E le E L I E ELES E LEA LL N E RASLE E ALAL L RSELEELSE E LRELESKRSELR 914
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462615508 333 QKYTNIVKEMKAKD L EIRIHKKKKCEIYR RL R E FAK L - YDTIRNER NK FVNLLHK A HQKVNEIKE 396
Cdd:TIGR02168 915 RELEELREKLAQLE L RLEGLEVRIDNLQE RL S E EYS L t LEEAEALE NK IEDDEEE A RRRLKRLEN 979
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
256-649
6.15e-05
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 46.97
E-value: 6.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 256 ERR R E LHKEV E VAKR NL AQ - QK I IS E M E SK L V ---- EQQL AE EN K L LK EQENMK EL VVNL LR MTQ i KID E K E QKSKDFLK 330
Cdd:TIGR02168 172 ERR K E TERKL E RTRE NL DR l ED I LN E L E RQ L K sler QAEK AE RY K E LK AELREL EL ALLV LR LEE - LRE E L E ELQEELKE 250
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 331 A QQKYTNIVK E MKAKDLEIRIHKKKK ceiyrrlrefaklydtirnernkfvnll HKAHQKVN E IKER hkms L NE L EILRN 410
Cdd:TIGR02168 251 A EEELEELTA E LQELEEKLEELRLEV ---------------------------- SELEEEIE E LQKE ---- L YA L ANEIS 298
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 411 SAVS Q ERK L QNSM lkh AN NVTIR E SMQNDVRKIV SKL Q E MK E KKEAQLNNIDR L ANTITMI E E E MVQ L RKRY E KAVQHRN 490
Cdd:TIGR02168 299 RLEQ Q KQI L RERL --- AN LERQL E ELEAQLEELE SKL D E LA E ELAELEEKLEE L KEELESL E A E LEE L EAEL E ELESRLE 375
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 491 E sgvqliereeeicifyekiniqekmklngeieihl LEE KIQF L KM K I A EKQR QI CVTQKLL pak RS L D A D L AV L QIQFS 570
Cdd:TIGR02168 376 E ----------------------------------- LEE QLET L RS K V A QLEL QI ASLNNEI --- ER L E A R L ER L EDRRE 417
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462615508 571 QCTDR I KD L E K QFVKPDGENRARF L PGKDLTEK E MIQK L DK LE LQ L AKKE E K L L E KDFIYEQVS R LTDR L CSKTQGCKQ 649
Cdd:TIGR02168 418 RLQQE I EE L L K KLEEAELKELQAE L EELEEELE E LQEE L ER LE EA L EELR E E L E E AEQALDAAE R ELAQ L QARLDSLER 496
PRK03918
PRK03918 DNA double-strand break repair ATPase Rad50;
15-420
1.72e-04
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain]
Cd Length: 880
Bit Score: 45.05
E-value: 1.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 15 E KIT K PGEME K KMKI L R E ST EEL R KE IMQKKLEIKN L R E DLASKQKQLLKEQ KE L EE l L GHQ V VLKD E VAHHQTIPVQIG 94
Cdd:PRK03918 221 E ELE K LEKEV K ELEE L K E EI EEL E KE LESLEGSKRK L E E KIRELEERIEELK KE I EE - L EEK V KELK E LKEKAEEYIKLS 299
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 95 KEI E KITRKKV E M EK KKIV LE Q E VKTLNDSL K KV E N K VSAI v D E KENVI KE V E GKRAL LE IKEREHNQLVKLL E LARENE 174
Cdd:PRK03918 300 EFY E EYLDELR E I EK RLSR LE E E INGIEERI K EL E E K EERL - E E LKKKL KE L E KRLEE LE ERHELYEEAKAKK E ELERLK 378
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 175 A t S LT ERGILD L NLRNSLID K QN yh D E LSRKQREKERDFRN L R K MELL LK VSWDA L RQTQA ---------------- L HQ 238
Cdd:PRK03918 379 K - R LT GLTPEK L EKELEELE K AK -- E E IEEEISKITARIGE L K K EIKE LK KAIEE L KKAKG kcpvcgrelteehrke L LE 455
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 239 RLLL E MEA I P K DDSTLS E RR R E L H KE - V E VA K RNLAQQKI I S --------- E M E S KL VEQQ L A E EN K LLK E Q E NM KE LVV 308
Cdd:PRK03918 456 EYTA E LKR I E K ELKEIE E KE R K L R KE l R E LE K VLKKESEL I K lkelaeqlk E L E E KL KKYN L E E LE K KAE E Y E KL KE KLI 535
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 309 N L lr MTQ IK IDE KE QKSKDF LK aqqkytniv K EMKAKDLEIRIHKKKKC E IYRR L R E FAKLYDTIRN ER N K FVNLLHKAH 388
Cdd:PRK03918 536 K L -- KGE IK SLK KE LEKLEE LK --------- K KLAELEKKLDELEEELA E LLKE L E E LGFESVEELE ER L K ELEPFYNEY 604
410 420 430
....*....|....*....|....*....|..
gi 2462615508 389 QKVNEIKERHKMSLN EL EI L RNSAVSQERK L Q 420
Cdd:PRK03918 605 LELKDAEKELEREEK EL KK L EEELDKAFEE L A 636
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
96-349
3.91e-04
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 44.16
E-value: 3.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 96 EIEKITRKKV E M E KKKIV LE Q E VKT L NDS L KKV E NKVSAIVD E K E NVIK E V E GKR A LLEIKER E HNQ L VKLLELAR E NEA 175
Cdd:COG1196 233 KLRELEAELE E L E AELEE LE A E LEE L EAE L AEL E AELEELRL E L E ELEL E L E EAQ A EEYELLA E LAR L EQDIARLE E RRR 312
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 176 TSLTERGI L DLN L RNSLIDKQNYHD EL SRKQR E K E RDFRN L RKM E LL L KVSWD AL RQTQ A LHQRLLL E M E AIPKDDSTLS 255
Cdd:COG1196 313 ELEERLEE L EEE L AELEEELEELEE EL EELEE E L E EAEEE L EEA E AE L AEAEE AL LEAE A ELAEAEE E L E ELAEELLEAL 392
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 256 ERRR EL HKEV E VAKRNLAQQKIIS E MESKLV E QQLAEENK L LK E Q E NMK E LVVNLLRMTQIKID E K E QKSKDFLKAQQKY 335
Cdd:COG1196 393 RAAA EL AAQL E ELEEAEEALLERL E RLEEEL E ELEEALAE L EE E E E EEE E ALEEAAEEEAELEE E E E ALLELLAELLEEA 472
250
....*....|....
gi 2462615508 336 TNIVKEMKAKDL E I 349
Cdd:COG1196 473 ALLEAALAELLE E L 486
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
22-328
4.64e-04
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 43.89
E-value: 4.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 22 E M E K K MKI L RESTE ELRKE IMQKKL E IKN LR ED L ASKQK Q LLKEQ K E L EE L LGHQVV L KDEV A HHQTIPVQIGK EIE KIT 101
Cdd:TIGR02168 688 E L E E K IAE L EKALA ELRKE LEELEE E LEQ LR KE L EELSR Q ISALR K D L AR L EAEVEQ L EERI A QLSKELTELEA EIE ELE 767
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 102 RKKV E M E KKKIVL E Q E VKT L NDSLKKVENKVS A IVDEKENVIK E VE gkrall EIK E REH N QLVK L LE L A R ENE A tsl TER 181
Cdd:TIGR02168 768 ERLE E A E EELAEA E A E IEE L EAQIEQLKEELK A LREALDELRA E LT ------ LLN E EAA N LRER L ES L E R RIA A --- TER 838
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 182 GIL DL NLR nsl I DKQNYHD E LSRKQR E KERDFRN -- LRKM E L LL KVSWDALRQTQA L HQR L LLEM E AIPKDD S TL SE R RR 259
Cdd:TIGR02168 839 RLE DL EEQ --- I EELSEDI E SLAAEI E ELEELIE el ESEL E A LL NERASLEEALAL L RSE L EELS E ELRELE S KR SE L RR 915
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462615508 260 EL HK - EVEV A KRN L AQQKI is E MESKLVEQQ L A EE NK L - L K E Q E NMKELVVNLLRMTQIKIDEK E Q K S K DF 328
Cdd:TIGR02168 916 EL EE l REKL A QLE L RLEGL -- E VRIDNLQER L S EE YS L t L E E A E ALENKIEDDEEEARRRLKRL E N K I K EL 984
CwlO1
COG3883 Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
22-175
5.48e-04
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain]
Cd Length: 379
Bit Score: 43.28
E-value: 5.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 22 EMEKKMKI L R E STE EL RK E IMQKKL EI KN L REDL A SKQKQLLKEQK EL E E LLGHQ ------------------------- 76
Cdd:COG3883 41 ALQAELEE L N E EYN EL QA E LEALQA EI DK L QAEI A EAEAEIEERRE EL G E RARAL yrsggsvsyldvllgsesfsdfldr 120
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 77 - VV L KDEVAHHQTIPVQIGKEIEKITR KK V E M E K K KIV LE QEVKT L NDSLKKV E NKVS aivd E K E NVIKEVEGKR A LL E I 155
Cdd:COG3883 121 l SA L SKIADADADLLEELKADKAELEA KK A E L E A K LAE LE ALKAE L EAAKAEL E AQQA ---- E Q E ALLAQLSAEE A AA E A 196
170 180
....*....|....*....|
gi 2462615508 156 KER E HNQLVKLL E L A RENE A 175
Cdd:COG3883 197 QLA E LEAELAAA E A A AAAA A 216
CCDC158
pfam15921 Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
22-585
6.89e-04
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain]
Cd Length: 1112
Bit Score: 43.18
E-value: 6.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 22 E MEK K MKI L - RESTEELRKE I MQKKL EI KN L R E DLA S KQK Q LLKE Q KE LE ellghqv VLKDEVAHHQTIPVQIGKEI E K - 99
Cdd:pfam15921 253 E SQN K IEL L l QQHQDRIEQL I SEHEV EI TG L T E KAS S ARS Q ANSI Q SQ LE ------- IIQEQARNQNSMYMRQLSDL E S t 325
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 100 ITRKKV E MEKK K IVL E QEVKT L NDS L KKVENKVSAIVD E KENVIK E V ----- EGKRA L LEIKE RE H nqlvkll EL AR E N E 174
Cdd:pfam15921 326 VSQLRS E LREA K RMY E DKIEE L EKQ L VLANSELTEART E RDQFSQ E S gnldd QLQKL L ADLHK RE K ------- EL SL E K E 398
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 175 ATSL ----- T ERG I LDLN LR NS L I D KQNYHDE L -------- S RK Q REK ER DFRNLR - K M E L L L KVS -- WDA L RQ T QALHQ 238
Cdd:pfam15921 399 QNKR lwdrd T GNS I TIDH LR RE L D D RNMEVQR L eallkamk S EC Q GQM ER QMAAIQ g K N E S L E KVS sl TAQ L ES T KEMLR 478
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 239 RLLL E ME A ---- IPKDDS T L S ERRRE L H - KE VEVAKR N LAQQ K II S EMES KL V E ----------- QQLAE E NKL LK E Q EN 302
Cdd:pfam15921 479 KVVE E LT A kkmt LESSER T V S DLTAS L Q e KE RAIEAT N AEIT K LR S RVDL KL Q E lqhlknegdhl RNVQT E CEA LK L Q MA 558
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 303 M K EL V VNL LR ----- MTQ IK idek E Q KSKDFLKA Q QKYTNIV KE MKAKD LE IRIH K KK K CEIYRRL RE FAKLYDTIRN E R 377
Cdd:pfam15921 559 E K DK V IEI LR qqien MTQ LV ---- G Q HGRTAGAM Q VEKAQLE KE INDRR LE LQEF K IL K DKKDAKI RE LEARVSDLEL E K 634
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 378 N K F VN LLHKAHQK V NE IK ERHKMS LNE LEIL RN -- SAV S QERKLQNSMLKHAN nvtir E S M QNDVR K IVSK L QEMKEKK E 455
Cdd:pfam15921 635 V K L VN AGSERLRA V KD IK QERDQL LNE VKTS RN el NSL S EDYEVLKRNFRNKS ----- E E M ETTTN K LKMQ L KSAQSEL E 709
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 456 AQL N NIDRLANTITMIEEEMVQLR K ryekavqhrnesgv Q LIEREEE I CIFYE KI NIQ E KMKL N GEI E I H L L E E KIQF L K 535
Cdd:pfam15921 710 QTR N TLKSMEGSDGHAMKVAMGMQ K -------------- Q ITAKRGQ I DALQS KI QFL E EAMT N ANK E K H F L K E EKNK L S 775
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462615508 536 MKIA ---- EK QRQICVTQK L LPAK R S L DADL A VLQI ------- QF SQ C T D R I KDL E KQF V K 585
Cdd:pfam15921 776 QELS tvat EK NKMAGELEV L RSQE R R L KEKV A NMEV aldkasl QF AE C Q D I I QRQ E QES V R 836
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
150-420
8.13e-04
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 42.98
E-value: 8.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 150 RA L L EIK E R E HNQ L VKL L EL A R E NEATSLT E RGI L D --------- LNLRNSL ID KQNYHD E LSRKQR E K ER dfrnlrkme 220
Cdd:COG4913 609 RA K L AAL E A E LAE L EEE L AE A E E RLEALEA E LDA L Q errealqrl AEYSWDE ID VASAER E IAELEA E L ER --------- 679
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 221 ll L KV S W D A L RQTQALHQR L LL E M E AIPKDDST L SERRRE L H KE V E V A KRN L AQQK ---- IISEMESKLVEQQ L A E ENKL 296
Cdd:COG4913 680 -- L DA S S D D L AALEEQLEE L EA E L E ELEEELDE L KGEIGR L E KE L E Q A EEE L DELQ drle AAEDLARLELRAL L E E RFAA 757
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 297 LKEQENMK EL VV NL LRMTQIKIDEKEQKSKDFLK A QQKY t N IVKEMKAK DL EIRI hkkkkceiy RR L R E FAK L Y D TIRNE 376
Cdd:COG4913 758 ALGDAVER EL RE NL EERIDALRARLNRAEEELER A MRAF - N REWPAETA DL DADL --------- ES L P E YLA L L D RLEED 827
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462615508 377 R ----------------- NKFVN LL H K AHQKVN EIKER hkms LNE L - EI L RNSAVSQE R K L Q 420
Cdd:COG4913 828 G lpeyeerfkellnensi EFVAD LL S K LRRAIR EIKER ---- IDP L n DS L KRIPFGPG R Y L R 885
DUF5401
pfam17380 Family of unknown function (DUF5401); This is a family of unknown function found in ...
138-458
8.34e-04
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain]
Cd Length: 722
Bit Score: 42.80
E-value: 8.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 138 EKE NVIK EVE GK R A L L E IKEREHNQLVKLLELAR E N E ATSL t ER gildlnlrnslidkqny HD EL S R - K Q R E KE R DFRNL 216
Cdd:pfam17380 304 EKE EKAR EVE RR R K L E E AEKARQAEMDRQAAIYA E Q E RMAM - ER ----------------- ER EL E R i R Q E E RK R ELERI 365
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 217 R KM E LLLKV S wd AL R QTQA L ------- HQ R LLL E M EA IP K DDSTLS ER R R ELHKEVEVAKRNL A Q Q KIISEM E SKLV E QQ 289
Cdd:pfam17380 366 R QE E IAMEI S -- RM R ELER L qmerqqk NE R VRQ E L EA AR K VKILEE ER Q R KIQQQKVEMEQIR A E Q EEARQR E VRRL E EE 443
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 290 L A E E NKLLKEQ E NMKELV V NL LR MTQ ikid E KEQKS K DF L KAQQKYTNIVK E MKA K D LE IRIHKK K KCE I yrrlrefakl 369
Cdd:pfam17380 444 R A R E MERVRLE E QERQQQ V ER LR QQE ---- E ERKRK K LE L EKEKRDRKRAE E QRR K I LE KELEER K QAM I ---------- 509
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 370 ydtir N E RN K FVN L LHKAHQKVNE I K E RHKMSLN E L E ILRNSAVSQE R KL Q NS M L K HANNVTIR E S M QND v R KIVSKLQ E 449
Cdd:pfam17380 510 ----- E E ER K RKL L EKEMEERQKA I Y E EERRREA E E E RRKQQEMEER R RI Q EQ M R K ATEERSRL E A M ERE - R EMMRQIV E 583
....*....
gi 2462615508 450 m K EK KE A QL 458
Cdd:pfam17380 584 - S EK AR A EY 591
DUF3584
pfam12128 Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
122-502
2.38e-03
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain]
Cd Length: 1191
Bit Score: 41.75
E-value: 2.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 122 NDSLKK V ENKVS AI VDEKEN V IKEVEGK R ALL E IKE R EHNQLVKLLELAR E NEATSLTERGILDLN LR N S LIDKQNYH DE 201
Cdd:pfam12128 192 EGKFRD V KSMIV AI LEDDGV V PPKSRLN R QQV E HWI R DIQAIAGIMKIRP E FTKLQQEFNTLESAE LR L S HLHFGYKS DE 271
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 202 LSRKQ R EK ER DFRNLRKME LL L kvswdalrqtqalhqrlllemeaip KD D STLS E R R R EL HK E VEV A KRNL A QQK ii SE M 281
Cdd:pfam12128 272 TLIAS R QE ER QETSAELNQ LL R ------------------------- TL D DQWK E K R D EL NG E LSA A DAAV A KDR -- SE L 324
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 282 E sklveqq LA E ENKLLKEQENMKELVVNLLRMTQIKID -- EK E QKS K DFLKAQ Q KY T N ivkem K AKDLEIR I HKKKKCE I 359
Cdd:pfam12128 325 E ------- AL E DQHGAFLDADIETAAADQEQLPSWQSE le NL E ERL K ALTGKH Q DV T A ----- K YNRRRSK I KEQNNRD I 392
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 360 YRRLREF AK LYDTIRNERNKFVNL L HKAHQKVN E IK E RH K MSL NE L E ILRN S AVSQERKLQ N S mlkhann V T IRESMQND 439
Cdd:pfam12128 393 AGIKDKL AK IREARDRQLAVAEDD L QALESELR E QL E AG K LEF NE E E YRLK S RLGELKLRL N Q ------- A T ATPELLLQ 465
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462615508 440 VRKIVSKLQEMK E KK EA QLNNID RL AN titmiee E MV Q L RKR YEK A VQHRNESGVQ L I ER EEE 502
Cdd:pfam12128 466 LENFDERIERAR E EQ EA ANAEVE RL QS ------- E LR Q A RKR RDQ A SEALRQASRR L E ER QSA 521
PTZ00121
PTZ00121 MAEBL; Provisional
11-502
2.56e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 41.67
E-value: 2.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 11 V K EFEKIT K PG E ME K KMKILREST E ELRKEIMQ KK L E IKNLRE D L A S K QKQLL K EQK E LEELLGHQVVLKD E V A HHQTIP 90
Cdd:PTZ00121 1289 K K KADEAK K AE E KK K ADEAKKKAE E AKKADEAK KK A E EAKKKA D A A K K KAEEA K KAA E AAKAEAEAAADEA E A A EEKAEA 1368
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 91 VQIG KE IE K itr KK VEME KKK ivl EQ E V K TLNDSL KK V E -- N K VSAIVDEKENVI K EVEGKRALL E I K EREHNQLV K LL E 168
Cdd:PTZ00121 1369 AEKK KE EA K --- KK ADAA KKK --- AE E K K KADEAK KK A E ed K K KADELKKAAAAK K KADEAKKKA E E K KKADEAKK K AE E 1442
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 169 LAREN EA TSLT E RGILDLNLRNSLIDKQN y H DE LSR K QR E KERDFRNLR K M E LLL K VSWD A LRQTQ A lh QRLLL E MEAIP 248
Cdd:PTZ00121 1443 AKKAD EA KKKA E EAKKAEEAKKKAEEAKK - A DE AKK K AE E AKKADEAKK K A E EAK K KADE A KKAAE A -- KKKAD E AKKAE 1519
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 249 KDDSTLSERRR E LH K EVEV AK R nl A QQ K IISEMES K LV E QQL AEE N K LLK E QENMK E LVVNL LR mtqi K ID E KEQKSKDF 328
Cdd:PTZ00121 1520 EAKKADEAKKA E EA K KADE AK K -- A EE K KKADELK K AE E LKK AEE K K KAE E AKKAE E DKNMA LR ---- K AE E AKKAEEAR 1593
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 329 LKAQQ K YTNIV K E MKA KDLEIRIHK K K K C E IYRRLR E FA K LYDTIRN --- E RN K FVNL L H KA HQ ---- K VN E IKERHKMS 401
Cdd:PTZ00121 1594 IEEVM K LYEEE K K MKA EEAKKAEEA K I K A E ELKKAE E EK K KVEQLKK kea E EK K KAEE L K KA EE enki K AA E EAKKAEED 1673
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 402 LNEL E ILR n S A VSQ E R K LQNSML K H A NNVTIR E SMQNDVRKIVS K LQ E M K EKK E AQLNNIDRLA ntitmi E E EMVQLR K R 481
Cdd:PTZ00121 1674 KKKA E EAK - K A EED E K K AAEALK K E A EEAKKA E ELKKKEAEEKK K AE E L K KAE E ENKIKAEEAK ------ K E AEEDKK K A 1746
490 500
....*....|....*....|.
gi 2462615508 482 Y E KAVQHRNESGVQLIER EEE 502
Cdd:PTZ00121 1747 E E AKKDEEEKKKIAHLKK EEE 1767
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
11-362
2.60e-03
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 41.59
E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 11 VK E FEKITKPG E MEKKM K ILRE S tee L RK E IMQKKLEIKN L RED L ASKQKQLLKEQ KE L E E L LGHQVV LK DEVAHHQTIP 90
Cdd:TIGR02169 670 RS E PAELQRLR E RLEGL K RELS S --- L QS E LRRIENRLDE L SQE L SDASRKIGEIE KE I E Q L EQEEEK LK ERLEELEEDL 746
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 91 VQIGK EIE KITRKKV E M E KKKIV LE QEVKT L NDS L KKV E ----- NKVSA I VD E KENVIK EV EGKR A L L EIK E REH N Q L VK 165
Cdd:TIGR02169 747 SSLEQ EIE NVKSELK E L E ARIEE LE EDLHK L EEA L NDL E arlsh SRIPE I QA E LSKLEE EV SRIE A R L REI E QKL N R L TL 826
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 166 LL E LARENEATSLTE R GI L DLN l RN S LIDKQ nyh DE L SR K QR E K E RDFRN L RKMELL L KVSWDA L RQTQALHQRL L L E M E 245
Cdd:TIGR02169 827 EK E YLEKEIQELQEQ R ID L KEQ - IK S IEKEI --- EN L NG K KE E L E EELEE L EAALRD L ESRLGD L KKERDELEAQ L R E L E 902
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 246 AIPKDDSTLS E RR R ELHK E VEVAKRN L AQQKIIS E MESKLV E QQLA EE NK L LKE Q ENMKELVVNLLRMTQIK --- I D E K E 322
Cdd:TIGR02169 903 RKIEELEAQI E KK R KRLS E LKAKLEA L EEELSEI E DPKGED E EIPE EE LS L EDV Q AELQRVEEEIRALEPVN mla I Q E Y E 982
330 340 350 360
....*....|....*....|....*....|....*....|
gi 2462615508 323 QKS K DFLKAQQ K YTNIVK E M KA KDLE I RIHK KKK C E IYRR 362
Cdd:TIGR02169 983 EVL K RLDELKE K RAKLEE E R KA ILER I EEYE KKK R E VFME 1022
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
30-545
2.62e-03
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 41.59
E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 30 L REST EEL RK EI MQKKLEIKN L R E DL A SKQKQ L LKEQK ELEE LLGHQVVLK DE VAHHQ tipvqig KEI EK IT R KKV E MEK 109
Cdd:TIGR02169 334 L LAEI EEL ER EI EEERKRRDK L T E EY A ELKEE L EDLRA ELEE VDKEFAETR DE LKDYR ------- EKL EK LK R EIN E LKR 406
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 110 KKIV L EQ E VKT L NDS L KKVENKVSA I VDEKENVIK E V E G K RALLEIK E REHN QL VKL L ELARE neatsltergildlnlr 189
Cdd:TIGR02169 407 ELDR L QE E LQR L SEE L ADLNAAIAG I EAKINELEE E K E D K ALEIKKQ E WKLE QL AAD L SKYEQ ----------------- 469
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 190 n S L I D KQNYH D ELSRKQREKE R D frn L RKM E LLLKV S WDAL R QTQ A LHQR L LLEMEAIPKDDST L SERRRELHKEV EVA K 269
Cdd:TIGR02169 470 - E L Y D LKEEY D RVEKELSKLQ R E --- L AEA E AQARA S EERV R GGR A VEEV L KASIQGVHGTVAQ L GSVGERYATAI EVA A 545
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 270 R N LAQQKIISE mesklv EQQLA E ENK LLK E qenmkelv VNLL R M T QIKIDEKEQKSK --------------- D FLKAQQ K 334
Cdd:TIGR02169 546 G N RLNNVVVED ------ DAVAK E AIE LLK R -------- RKAG R A T FLPLNKMRDERR dlsilsedgvigfav D LVEFDP K 611
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 335 Y TNIV K EM ----------- K A KD L EIRIH -------------------------------- KKKKCEIYR RL REFAKLYD 371
Cdd:TIGR02169 612 Y EPAF K YV fgdtlvvedie A A RR L MGKYR mvtlegelfeksgamtggsraprggilfsrse PAELQRLRE RL EGLKRELS 691
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 372 TIRN E RNKFV N L L HKAH Q KVNEIKERHKMSLN E L E I L RNSAVSQERK L QNSMLKHA --- NNVTIRE S MQNDVRKIVSK L Q 448
Cdd:TIGR02169 692 SLQS E LRRIE N R L DELS Q ELSDASRKIGEIEK E I E Q L EQEEEKLKER L EELEEDLS sle QEIENVK S ELKELEARIEE L E 771
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 449 E MKE K K E AQ LN NIDR --------- LANTITMI EEE MVQLRK R YEKAV Q HR N ESGVQLIER E E EI CIFY E KINIQEKMKLN 519
Cdd:TIGR02169 772 E DLH K L E EA LN DLEA rlshsripe IQAELSKL EEE VSRIEA R LREIE Q KL N RLTLEKEYL E K EI QELQ E QRIDLKEQIKS 851
570 580
....*....|....*....|....*.
gi 2462615508 520 G E I EI HL L EE K IQF L KMKIA E KQRQI 545
Cdd:TIGR02169 852 I E K EI EN L NG K KEE L EEELE E LEAAL 877
CCDC158
pfam15921 Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
108-682
3.02e-03
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain]
Cd Length: 1112
Bit Score: 41.26
E-value: 3.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 108 EK K K IV L E Q E V KT L NDS L KKVENKVS A IV D -------------- EKE N VIK E V E GKRA L L E - IK E REHN Q LVK L LELARE 172
Cdd:pfam15921 102 EK Q K FY L R Q S V ID L QTK L QEMQMERD A MA D irrresqsqedlrn QLQ N TVH E L E AAKC L K E d ML E DSNT Q IEQ L RKMMLS 181
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 173 N E ATSLTE R G IL d LNLRNSLID K QNY HD EL S ------------ RKQ RE KERDFRN L R ------------------- K M EL 221
Cdd:pfam15921 182 H E GVLQEI R S IL - VDFEEASGK K IYE HD SM S tmhfrslgsais KIL RE LDTEISY L K grifpvedqlealksesqn K I EL 260
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 222 LL KVSW D ALR Q TQAL H Q rll L E MEAIPKDD S TLSERRRELHKEV E VAKRNLAQ Q K ------------ II S EME S K L V E QQ 289
Cdd:pfam15921 261 LL QQHQ D RIE Q LISE H E --- V E ITGLTEKA S SARSQANSIQSQL E IIQEQARN Q N smymrqlsdles TV S QLR S E L R E AK 337
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 290 LAE E N K L lke Q E NM K E LV VNLLRM T QIKI d E KE Q K S KDFLKAQQKYTNIVKEMKAKDL E IRIH K KKKCEIYR R LREFAKL 369
Cdd:pfam15921 338 RMY E D K I --- E E LE K Q LV LANSEL T EART - E RD Q F S QESGNLDDQLQKLLADLHKREK E LSLE K EQNKRLWD R DTGNSIT 413
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 370 Y D TI R N E rnkfvnl L HKAHQK V NEIKERH K MSLN E LEILRNSAVSQERKLQN S ML K HANNVTIR ES MQNDV RK I V SK L Q e 449
Cdd:pfam15921 414 I D HL R R E ------- L DDRNME V QRLEALL K AMKS E CQGQMERQMAAIQGKNE S LE K VSSLTAQL ES TKEML RK V V EE L T - 485
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 450 mke K K EAQ L NNID R LANTI T MIEE E M vqlrkry E K A VQHR N ESGVQ L IE R EE eicifyek INI QE KMK L NG E IE i HL -- L 527
Cdd:pfam15921 486 --- A K KMT L ESSE R TVSDL T ASLQ E K ------- E R A IEAT N AEITK L RS R VD -------- LKL QE LQH L KN E GD - HL rn V 546
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 528 EEKIQF LK MKI AEK QRQ I CVTQKLLPAKRS L DAD ---- LAVL Q IQFS Q CTDR I K D -- LE K Q FV K PDGEN rarflpg KD LT 601
Cdd:pfam15921 547 QTECEA LK LQM AEK DKV I EILRQQIENMTQ L VGQ hgrt AGAM Q VEKA Q LEKE I N D rr LE L Q EF K ILKDK ------- KD AK 619
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 602 EK E MIQKLDK LEL QLA K KEEKLL E KDFIYEQVSRLT D R L CSKTQGCKQDTLL L AKKMNGYQ R RIK N AT E K M MALVAE L S M 681
Cdd:pfam15921 620 IR E LEARVSD LEL EKV K LVNAGS E RLRAVKDIKQER D Q L LNEVKTSRNELNS L SEDYEVLK R NFR N KS E E M ETTTNK L K M 699
.
gi 2462615508 682 K 682
Cdd:pfam15921 700 Q 700
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
355-626
3.66e-03
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 41.08
E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 355 K K C E I YR R L R E FA K LYD tirne RNKFVNL L HKAHQKVN E IKERHKMSLN ELE I L RNSAVSQ E RK L QNSM L KHANNVTIR E 434
Cdd:COG1196 210 E K A E R YR E L K E EL K ELE ----- AELLLLK L RELEAELE E LEAELEELEA ELE E L EAELAEL E AE L EELR L ELEELELEL E 284
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 435 SM Q NDVRKIVSK L QEMKEKKEAQLNNIDR L ANTITMI EEE MVQ L RKRY E KAVQHRN E SGVQ L I E R EEE ICIFYEKINIQ E 514
Cdd:COG1196 285 EA Q AEEYELLAE L ARLEQDIARLEERRRE L EERLEEL EEE LAE L EEEL E ELEEELE E LEEE L E E A EEE LEEAEAELAEA E 364
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 515 KMK L NG E I E IHLL EE KIQF L KMKIA E KQ R QICVTQKL L PAKRSLDAD L AVLQIQFSQCTDRIKDLEKQFVKPDG E NRA rf 594
Cdd:COG1196 365 EAL L EA E A E LAEA EE ELEE L AEELL E AL R AAAELAAQ L EELEEAEEA L LERLERLEEELEELEEALAELEEEEE E EEE -- 442
250 260 270
....*....|....*....|....*....|..
gi 2462615508 595 lpg KDLTEK E MIQK L DKL E LQ L AKKEEK LLE K 626
Cdd:COG1196 443 --- ALEEAA E EEAE L EEE E EA L LELLAE LLE E 471
PTZ00121
PTZ00121 MAEBL; Provisional
6-627
3.94e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 40.89
E-value: 3.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 6 E KIIIVKEF E KITKPG E ME KK MKILRESTEELRK E IMQ K KLEIKNLR E DLASKQKQLLK E QKEL E ELLGHQVVL K D E V A H 85
Cdd:PTZ00121 1085 E DNRADEAT E EAFGKA E EA KK TETGKAEEARKAE E AKK K AEDARKAE E ARKAEDARKAE E ARKA E DAKRVEIAR K A E D A R 1164
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 86 HQTIP -- VQIG K EI E K i T RK KV E ME K KKIVLEQ E VKTLNDSLK K V E NKVS A IVDE K ENVI K EV E GKRALL E I K EREH n QL 163
Cdd:PTZ00121 1165 KAEEA rk AEDA K KA E A - A RK AE E VR K AEELRKA E DARKAEAAR K A E EERK A EEAR K AEDA K KA E AVKKAE E A K KDAE - EA 1242
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 164 V K LL E LAREN E ATSLT E RGILDLNL R NSL I DKQNYHDELSR K QR E KERDFRNLR K M E LLL K VSWDALRQTQ A LH - QRLLL 242
Cdd:PTZ00121 1243 K K AE E ERNNE E IRKFE E ARMAHFAR R QAA I KAEEARKADEL K KA E EKKKADEAK K A E EKK K ADEAKKKAEE A KK a DEAKK 1322
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 243 EM E AIP K DDSTLSERRR E LH K EV E V AK RNLAQQKIIS E MESKLV E QQLAEENKLL K EQENM K ELVVNLLRMTQI K IDEK E 322
Cdd:PTZ00121 1323 KA E EAK K KADAAKKKAE E AK K AA E A AK AEAEAAADEA E AAEEKA E AAEKKKEEAK K KADAA K KKAEEKKKADEA K KKAE E 1402
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 323 Q K S K - D F LK AQQKYTNIVK E M K A K DL E IRIHK -- KKK C E IYRRLR E FA K LYD tirn E RN K FVNLLH KA HQ -- K VN E I K ER 397
Cdd:PTZ00121 1403 D K K K a D E LK KAAAAKKKAD E A K K K AE E KKKAD ea KKK A E EAKKAD E AK K KAE ---- E AK K AEEAKK KA EE ak K AD E A K KK 1478
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 398 HKMS l NELEILRNS A VSQER K LQNSMLKHANNVTIR E SMQNDVR K IVSKLQEMK E K K E A - QLNNIDRLANTITMIEE E MV 476
Cdd:PTZ00121 1479 AEEA - KKADEAKKK A EEAKK K ADEAKKAAEAKKKAD E AKKAEEA K KADEAKKAE E A K K A d EAKKAEEKKKADELKKA E EL 1557
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 477 QLRKRYE KA VQ - HRN E SGVQLIE R EE E ICIFY E KIN I Q E K MKL NG E ieihll E E K IQFLKM K I AE KQR qicvt Q K LLPA K 555
Cdd:PTZ00121 1558 KKAEEKK KA EE a KKA E EDKNMAL R KA E EAKKA E EAR I E E V MKL YE E ------ E K K MKAEEA K K AE EAK ----- I K AEEL K 1626
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462615508 556 RSLDADLA V L Q IQFSQCTDRI K DL E KQFVKPDGENR A RFLPG K DLTE K EMIQKLD K L E LQLA K KE E K L LEKD 627
Cdd:PTZ00121 1627 KAEEEKKK V E Q LKKKEAEEKK K AE E LKKAEEENKIK A AEEAK K AEED K KKAEEAK K A E EDEK K AA E A L KKEA 1698
235kDa-fam
TIGR01612 reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
250-472
5.51e-03
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain]
Cd Length: 2757
Bit Score: 40.42
E-value: 5.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 250 D DSTLSERRR E LH K EV E VAKRNLAQQ K I I SEMES KL veqq L A E ENKLL K EQENMK E LV ------- V NL LRMTQI KIDE KE 322
Cdd:TIGR01612 1160 D KAISNDDPE E IE K KI E NIVTKIDKK K N I YDEIK KL ---- L N E IAEIE K DKTSLE E VK ginlsyg K NL GKLFLE KIDE EK 1235
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 323 Q KS KDFL KA QQK Y TNIVK E M K A K DL EI RIHKKKKCE I YRRLRE F A ------ K LYDT I RNERNKFVNLLHKAHQ K VN E IKE 396
Cdd:TIGR01612 1236 K KS EHMI KA MEA Y IEDLD E I K E K SP EI ENEMGIEMD I KAEMET F N ishddd K DHHI I SKKHDENISDIREKSL K II E DFS 1315
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462615508 397 R h KMSL N ELEILRNSAVSQER K LQNSMLKHA N NVTIRESM -- Q N DVR KI VSKLQ E MKEKK E AQLN NI - D R L ANTITM I E 472
Cdd:TIGR01612 1316 E - ESDI N DIKKELQKNLLDAQ K HNSDINLYL N EIANIYNI lk L N KIK KI IDEVK E YTKEI E ENNK NI k D E L DKSEKL I K 1393
PRK00409
PRK00409 recombination and DNA strand exchange inhibitor protein; Reviewed
21-176
7.08e-03
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain]
Cd Length: 782
Bit Score: 39.81
E-value: 7.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 21 GE MEK K MKI L RE S T EEL RK E IM QK KL E IKN L REDLASKQKQ L LKEQKE L E E LL g HQVVLKD E VAHH Q T I p VQIG KE IEK I 100
Cdd:PRK00409 512 GE DKE K LNE L IA S L EEL ER E LE QK AE E AEA L LKEAEKLKEE L EEKKEK L Q E EE - DKLLEEA E KEAQ Q A I - KEAK KE ADE I 589
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462615508 101 TRKKVEME K KKIV ------ L EQEV K T LN DSLK K V E N K V sai VDE KE NVIKEVE G KR alle I K EREHN Q LVKL L ELAREN E 174
Cdd:PRK00409 590 IKELRQLQ K GGYA svkahe L IEAR K R LN KANE K K E K K K --- KKQ KE KQEELKV G DE ---- V K YLSLG Q KGEV L SIPDDK E 662
..
gi 2462615508 175 A T 176
Cdd:PRK00409 663 A I 664
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
