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Conserved domains on  [gi|2462626554|ref|XP_054219836|]
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caspase activity and apoptosis inhibitor 1 isoform X1 [Homo sapiens]

Protein Classification

CAAP1 domain-containing protein( domain architecture ID 10633997)

CAAP1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAAP1 pfam15335
Caspase activity and apoptosis inhibitor 1; CAAP1, or caspase activity and apoptosis inhibitor ...
 133-195 2.46e-28

Caspase activity and apoptosis inhibitor 1; CAAP1, or caspase activity and apoptosis inhibitor 1, is a family of eukaryotic proteins involved in the regulation of apoptosis. It modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop.


:

Pssm-ID: 464655 [Multi-domain]  Cd Length: 63  Bit Score: 101.90  E-value: 2.46e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462626554 133 LKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQEQLELLSEKKILKIL 195
Cdd:pfam15335   1 LKPLSAYIDDREELLEQCFSVLKPKKLKKMLPDELKDCSLEELKELCLEQLLGMSEKRLLSIL 63
 
Name Accession Description Interval E-value
CAAP1 pfam15335
Caspase activity and apoptosis inhibitor 1; CAAP1, or caspase activity and apoptosis inhibitor ...
 133-195 2.46e-28

Caspase activity and apoptosis inhibitor 1; CAAP1, or caspase activity and apoptosis inhibitor 1, is a family of eukaryotic proteins involved in the regulation of apoptosis. It modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop.


Pssm-ID: 464655 [Multi-domain]  Cd Length: 63  Bit Score: 101.90  E-value: 2.46e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462626554 133 LKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQEQLELLSEKKILKIL 195
Cdd:pfam15335   1 LKPLSAYIDDREELLEQCFSVLKPKKLKKMLPDELKDCSLEELKELCLEQLLGMSEKRLLSIL 63
 
Name Accession Description Interval E-value
CAAP1 pfam15335
Caspase activity and apoptosis inhibitor 1; CAAP1, or caspase activity and apoptosis inhibitor ...
 133-195 2.46e-28

Caspase activity and apoptosis inhibitor 1; CAAP1, or caspase activity and apoptosis inhibitor 1, is a family of eukaryotic proteins involved in the regulation of apoptosis. It modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop.


Pssm-ID: 464655 [Multi-domain]  Cd Length: 63  Bit Score: 101.90  E-value: 2.46e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462626554 133 LKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQEQLELLSEKKILKIL 195
Cdd:pfam15335   1 LKPLSAYIDDREELLEQCFSVLKPKKLKKMLPDELKDCSLEELKELCLEQLLGMSEKRLLSIL 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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